GREMLIN Database
Q7LXZ8 - N-terminal acetyltransferase complex ard1 subunit
UniProt: Q7LXZ8 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 151 (130)
Sequences: 12108 (9565)
Seq/√Len: 838.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
5_T47_K3.2421.00
91_E122_Y3.0481.00
21_E74_E2.9391.00
46_A82_I2.5081.00
84_A120_N2.4441.00
56_I90_I2.4431.00
5_T11_D2.3571.00
84_A119_A2.3441.00
58_G90_I2.1361.00
124_I127_V2.1031.00
88_N120_N2.0201.00
45_V52_V2.0011.00
53_V77_Y1.9981.00
91_E102_S1.8291.00
44_L89_E1.7961.00
13_D29_Y1.7711.00
7_A15_I1.7711.00
114_I118_R1.7491.00
115_S118_R1.7381.00
54_G73_V1.7271.00
118_R124_I1.7241.00
66_G94_F1.7171.00
93_R96_L1.6941.00
48_Q77_Y1.6721.00
7_A45_V1.6461.00
89_E92_E1.6451.00
43_Y57_I1.6281.00
77_Y80_Q1.6021.00
78_R112_S1.5521.00
93_R97_N1.5411.00
22_S72_A1.5261.00
104_L117_Y1.5161.00
48_Q53_V1.4981.00
14_Q17_Q1.4911.00
87_L120_N1.4751.00
21_E75_P1.4551.00
42_L93_R1.4251.00
16_F20_T1.3821.00
114_I124_I1.3741.00
51_K74_E1.3001.00
47_K52_V1.2891.00
60_I99_A1.2701.00
73_V82_I1.2571.00
17_Q21_E1.2571.00
29_Y33_R1.2541.00
14_Q52_V1.2261.00
84_A88_N1.2261.00
44_L93_R1.2181.00
11_D47_K1.2111.00
108_T127_V1.1991.00
16_F29_Y1.1921.00
48_Q80_Q1.1911.00
9_E33_R1.1481.00
106_V110_N1.1341.00
47_K50_E1.1301.00
21_E76_I1.1281.00
51_K76_I1.1271.00
42_L97_N1.1221.00
56_I86_L1.0951.00
58_G94_F1.0531.00
65_R103_Y1.0521.00
113_A117_Y1.0481.00
89_E93_R1.0391.00
18_I22_S1.0081.00
9_E37_F1.0021.00
23_F72_A0.9941.00
85_K88_N0.9871.00
94_F102_S0.9851.00
111_L114_I0.9831.00
111_L115_S0.9791.00
65_R101_Y0.9741.00
81_G84_A0.9631.00
19_E55_Y0.9561.00
56_I68_I0.9491.00
14_Q51_K0.9271.00
4_I89_E0.9261.00
19_E32_L0.9091.00
67_H103_Y0.9091.00
33_R37_F0.9051.00
92_E96_L0.9001.00
7_A43_Y0.8951.00
102_S122_Y0.8951.00
30_S34_A0.8821.00
66_G99_A0.8781.00
17_Q74_E0.8671.00
48_Q51_K0.8671.00
4_I85_K0.8631.00
59_I69_V0.8611.00
68_I87_L0.8581.00
42_L58_G0.8571.00
79_K112_S0.8571.00
51_K77_Y0.8531.00
74_E77_Y0.8461.00
22_S75_P0.8451.00
4_I44_L0.8451.00
116_F120_N0.8441.00
13_D17_Q0.8381.00
94_F99_A0.8371.00
103_Y125_M0.8291.00
8_T11_D0.8291.00
101_Y125_M0.8271.00
46_A53_V0.8221.00
31_L35_Y0.8191.00
32_L35_Y0.7991.00
53_V82_I0.7911.00
17_Q51_K0.7901.00
19_E70_S0.7751.00
60_I97_N0.7741.00
15_I55_Y0.7731.00
104_L113_A0.7711.00
28_P31_L0.7711.00
19_E23_F0.7671.00
12_L16_F0.7661.00
22_S78_R0.7611.00
18_I74_E0.7571.00
106_V114_I0.7481.00
106_V113_A0.7481.00
91_E120_N0.7431.00
87_L116_F0.7421.00
67_H105_E0.7321.00
18_I52_V0.7191.00
110_N113_A0.7191.00
46_A54_G0.7181.00
57_I69_V0.7151.00
30_S33_R0.7031.00
7_A12_L0.6951.00
9_E12_L0.6911.00
85_K89_E0.6901.00
46_A86_L0.6821.00
6_D44_L0.6791.00
6_D42_L0.6751.00
88_N92_E0.6501.00
54_G82_I0.6481.00
5_T45_V0.6441.00
87_L117_Y0.6401.00
46_A85_K0.6391.00
34_A38_L0.6351.00
16_F32_L0.6351.00
12_L36_L0.6341.00
73_V83_G0.6301.00
14_Q47_K0.6261.00
113_A116_F0.6231.00
35_Y57_I0.6231.00
118_R123_L0.6211.00
14_Q18_I0.6201.00
82_I85_K0.6191.00
91_E95_K0.6091.00
79_K119_A0.6061.00
89_E96_L0.6051.00
61_Q65_R0.6041.00
31_L34_A0.6041.00
112_S115_S0.5961.00
56_I71_I0.5931.00
54_G86_L0.5861.00
79_K115_S0.5851.00
7_A11_D0.5831.00
92_E95_K0.5811.00
73_V86_L0.5801.00
88_N91_E0.5781.00
23_F70_S0.5781.00
75_P78_R0.5771.00
60_I66_G0.5761.00
42_L60_I0.5751.00
35_Y41_K0.5721.00
18_I72_A0.5711.00
111_L118_R0.5711.00
68_I122_Y0.5701.00
87_L122_Y0.5681.00
46_A73_V0.5681.00
61_Q67_H0.5671.00
14_Q74_E0.5661.00
13_D16_F0.5611.00
71_I87_L0.5571.00
77_Y82_I0.5561.00
57_I70_S0.5561.00
35_Y38_L0.5551.00
58_G93_R0.5511.00
6_D93_R0.5481.00
27_Y70_S0.5461.00
38_L41_K0.5301.00
83_G116_F0.5291.00
4_I46_A0.5231.00
62_Y65_R0.5221.00
17_Q20_T0.5211.00
71_I117_Y0.5201.00
55_Y72_A0.5171.00
65_R128_R0.5171.00
31_L59_I0.5171.00
58_G66_G0.5141.00
106_V117_Y0.5131.00
5_T8_T0.5101.00
58_G102_S0.5091.00
68_I71_I0.5061.00
110_N114_I0.5031.00
34_A37_F0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4kvxA 1 0.9536 99.9 0.278 Contact Map
4pv6C 3 0.9934 99.9 0.292 Contact Map
2ob0A 1 0.9934 99.9 0.301 Contact Map
2cntA 1 0.9801 99.9 0.303 Contact Map
4r3lA 1 0.9603 99.9 0.305 Contact Map
2reeA 1 0.9801 99.9 0.312 Contact Map
2r7hA 2 0.9669 99.9 0.315 Contact Map
1s3zA 2 0.894 99.9 0.334 Contact Map
3fixA 2 0.9073 99.9 0.335 Contact Map
3kkwA 1 0.9603 99.9 0.335 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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