Q7LXX7 - SULSO - GREMLIN Contacts

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Q7LXX7 - Uncharacterized protein

UniProt:	Q7LXX7	Sequences: MIKLKLKLFKKMNLFELMNTRINENIKYYGDDMERLRKEYIVMLFLMPLISSISIILYLKISPYFLLLNIMNVFIYFFPILITQIRKDEQRKLIENEMPVFLLFAYVNSLLGRNLYKTFEEIRNSKVFKGLRREAMLLVKEVEVLGKSSFSAMESRAKAHRGDFLGKIYTVYTSGESIGISMPERLKDLLNETIDGLNSNFQGYVEKVNELVEILFMLFLITPMILLAFQYISSSINIFELIFPLLLFPIIFFYISLIQPNIGYDIKIDIKEVKNSLYILPIPFILVFLFHLSLEYEILVFYSIFIMFSFFIYRKISVADAILNNLPYILSDIADYLKIGYSIKSAILKLNVDNTHFRMFLGELAAKIRKNEAISNVRTNIWIVNAILELIENIDKKGFADTYTFKDLSLILYNYTSLRKKVLQNLRLFSILATITPIVFYFALGIMSKIRAVGNLDLIIVLYTMALSIIYAKVSRFTVFNFPLLVLALMNLIIVLLFGNVILTFI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	506 (465)
Sequences:	417 (334)
Seq/√Len:	15.5

HALSA - Q9HQY4 Q9HR80
SULSO - Q7LXX7 Q97VE7 Q97W54 Q97WB8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
373_A	376_N	4.528	1.00
434_T	485_L	4.333	1.00
277_L	282_I	4.006	1.00
278_Y	282_I	3.846	1.00
105_A	118_T	3.784	1.00
239_F	243_F	3.622	1.00
148_S	151_S	3.555	0.99
442_F	446_I	3.514	0.99
120_E	143_E	3.214	0.99
138_L	169_Y	3.193	0.99
94_I	160_H	3.080	0.98
277_L	281_P	2.896	0.98
284_F	288_F	2.879	0.97
468_S	472_A	2.729	0.96
45_F	362_G	2.702	0.96
375_S	452_A	2.639	0.96
280_L	284_F	2.529	0.95
470_I	476_R	2.440	0.93
210_E	233_S	2.416	0.93
94_I	168_I	2.379	0.93
278_Y	281_P	2.327	0.92
295_E	305_F	2.326	0.92
469_I	479_V	2.299	0.91
468_S	482_F	2.277	0.91
63_P	66_L	2.254	0.90
45_F	61_I	2.136	0.88
277_L	280_L	2.098	0.87
277_L	290_F	2.095	0.87
48_P	324_N	2.081	0.86
246_L	347_I	2.066	0.86
470_I	474_V	2.060	0.86
42_V	75_I	2.047	0.85
231_Y	467_L	2.003	0.84
54_S	208_V	2.003	0.84
280_L	285_I	1.978	0.83
297_E	301_F	1.977	0.83
138_L	153_M	1.969	0.83
482_F	485_L	1.968	0.83
323_L	381_I	1.932	0.82
57_L	124_N	1.914	0.81
35_R	42_V	1.890	0.80
109_S	128_F	1.890	0.80
62_S	78_F	1.880	0.80
171_V	189_L	1.873	0.80
294_L	298_I	1.829	0.78
140_K	312_I	1.824	0.78
322_I	447_M	1.818	0.77
104_F	334_A	1.814	0.77
243_F	249_P	1.812	0.77
168_I	356_H	1.799	0.77
479_V	482_F	1.796	0.77
219_F	344_K	1.788	0.76
47_M	57_L	1.783	0.76
71_M	74_F	1.781	0.76
179_G	213_E	1.769	0.75
255_I	263_G	1.769	0.75
288_F	291_H	1.754	0.75
55_I	74_F	1.722	0.73
171_V	185_R	1.699	0.72
276_S	283_P	1.699	0.72
240_E	247_L	1.684	0.72
444_L	448_S	1.667	0.71
292_L	300_V	1.663	0.71
55_I	452_A	1.644	0.70
205_V	422_V	1.642	0.70
99_P	390_L	1.632	0.69
46_L	59_L	1.630	0.69
101_F	105_A	1.620	0.69
330_L	405_F	1.618	0.69
487_L	490_M	1.613	0.68
40_Y	48_P	1.606	0.68
103_L	176_E	1.603	0.68
464_T	468_S	1.598	0.68
471_Y	476_R	1.593	0.67
282_I	285_I	1.575	0.66
285_I	298_I	1.566	0.66
482_F	486_V	1.557	0.65
49_L	305_F	1.534	0.64
470_I	479_V	1.534	0.64
215_L	485_L	1.533	0.64
145_L	323_L	1.532	0.64
256_S	260_P	1.525	0.64
37_R	242_I	1.516	0.63
302_Y	461_V	1.515	0.63
316_I	347_I	1.514	0.63
40_Y	245_L	1.506	0.63
138_L	229_F	1.495	0.62
373_A	421_K	1.491	0.62
66_L	301_F	1.476	0.61
96_N	334_A	1.451	0.60
285_I	292_L	1.449	0.60
46_L	69_N	1.448	0.60
56_I	306_I	1.444	0.59
24_E	27_K	1.441	0.59
46_L	52_S	1.440	0.59
243_F	247_L	1.439	0.59
145_L	334_A	1.432	0.59
53_I	58_Y	1.426	0.58
215_L	357_F	1.402	0.57
52_S	55_I	1.398	0.57
301_F	304_I	1.395	0.57
107_V	178_I	1.391	0.56
286_L	372_E	1.390	0.56
440_F	445_G	1.386	0.56
394_I	404_T	1.385	0.56
71_M	285_I	1.383	0.56
472_A	482_F	1.377	0.56
46_L	71_M	1.376	0.56
45_F	53_I	1.376	0.56
471_Y	477_F	1.369	0.55
62_S	494_I	1.367	0.55
373_A	461_V	1.366	0.55
334_A	378_R	1.352	0.54
338_K	371_N	1.350	0.54
469_I	473_K	1.348	0.54
52_S	58_Y	1.343	0.54
442_F	445_G	1.339	0.54
160_H	213_E	1.337	0.53
225_I	232_I	1.335	0.53
280_L	298_I	1.326	0.53
191_N	455_N	1.326	0.53
59_L	67_L	1.325	0.53
305_F	483_P	1.320	0.52
287_V	291_H	1.320	0.52
138_L	491_N	1.315	0.52
158_K	300_V	1.314	0.52
109_S	205_V	1.312	0.52
334_A	381_I	1.311	0.52
57_L	292_L	1.309	0.52
65_F	69_N	1.303	0.51
277_L	285_I	1.302	0.51
128_F	386_A	1.292	0.51
276_S	280_L	1.288	0.51
289_L	487_L	1.287	0.51
242_I	249_P	1.283	0.50
128_F	422_V	1.279	0.50
439_V	444_L	1.276	0.50
167_K	434_T	1.271	0.50
48_P	293_S	1.270	0.50
204_Y	223_P	1.257	0.49
91_R	483_P	1.246	0.48
41_I	46_L	1.241	0.48
45_F	66_L	1.241	0.48
289_L	304_I	1.238	0.48
111_L	337_L	1.236	0.48
436_T	440_F	1.234	0.48
239_F	250_I	1.228	0.47
168_I	334_A	1.222	0.47
219_F	223_P	1.213	0.46
292_L	299_L	1.212	0.46
248_F	286_L	1.207	0.46
39_E	79_P	1.207	0.46
56_I	294_L	1.202	0.46
484_L	496_L	1.200	0.46
106_Y	404_T	1.192	0.45
70_I	290_F	1.192	0.45
310_F	324_N	1.189	0.45
151_S	322_I	1.186	0.45
56_I	246_L	1.181	0.45
57_L	300_V	1.181	0.45
278_Y	291_H	1.176	0.44
280_L	290_F	1.172	0.44
329_I	434_T	1.169	0.44
275_N	310_F	1.167	0.44
46_L	288_F	1.166	0.44
329_I	354_N	1.166	0.44
433_A	436_T	1.164	0.44
467_L	472_A	1.163	0.44
51_S	253_F	1.154	0.43
56_I	62_S	1.154	0.43
195_D	462_L	1.150	0.43
491_N	499_G	1.149	0.43
488_A	493_I	1.144	0.42
354_N	434_T	1.142	0.42
283_P	302_Y	1.142	0.42
178_I	422_V	1.141	0.42
285_I	288_F	1.138	0.42
115_L	255_I	1.136	0.42
248_F	251_I	1.131	0.42
52_S	361_L	1.131	0.42
276_S	289_L	1.130	0.42
170_T	442_F	1.129	0.42
198_N	414_N	1.128	0.42
299_L	304_I	1.127	0.42
294_L	452_A	1.127	0.42
40_Y	182_M	1.126	0.41
472_A	486_V	1.126	0.41
318_V	498_F	1.124	0.41
377_V	432_L	1.118	0.41
207_K	388_L	1.115	0.41
135_A	368_I	1.115	0.41
44_L	48_P	1.109	0.41
195_D	459_I	1.107	0.40
202_Q	342_S	1.106	0.40
154_E	185_R	1.105	0.40
168_I	211_L	1.105	0.40
425_N	461_V	1.103	0.40
238_I	279_I	1.099	0.40
295_E	298_I	1.096	0.40
130_G	218_L	1.093	0.40
251_I	279_I	1.092	0.40
426_L	475_S	1.090	0.39
203_G	259_Q	1.088	0.39
55_I	242_I	1.087	0.39
313_Y	317_S	1.085	0.39
214_I	230_Q	1.084	0.39
224_M	337_L	1.083	0.39
82_I	260_P	1.082	0.39
43_M	373_A	1.082	0.39
162_G	213_E	1.080	0.39
282_I	291_H	1.079	0.39
119_F	122_I	1.073	0.39
225_I	424_Q	1.071	0.38
64_Y	452_A	1.071	0.38
26_I	47_M	1.070	0.38
172_Y	259_Q	1.063	0.38
107_V	408_L	1.062	0.38
94_I	134_E	1.058	0.38
240_E	250_I	1.057	0.38
237_N	286_L	1.051	0.37
351_N	424_Q	1.051	0.37
240_E	243_F	1.051	0.37
218_L	233_S	1.050	0.37
472_A	475_S	1.050	0.37
353_D	364_L	1.050	0.37
295_E	300_V	1.049	0.37
276_S	288_F	1.048	0.37
154_E	168_I	1.048	0.37
241_L	476_R	1.044	0.37
362_G	494_I	1.043	0.37
487_L	494_I	1.043	0.37
255_I	260_P	1.042	0.37
251_I	293_S	1.041	0.37
354_N	485_L	1.040	0.37
44_L	279_I	1.037	0.37
84_Q	87_K	1.036	0.37
49_L	78_F	1.035	0.37
407_D	436_T	1.028	0.36
168_I	231_Y	1.028	0.36
169_Y	306_I	1.021	0.36
99_P	190_L	1.018	0.36
61_I	70_I	1.015	0.35
49_L	282_I	1.011	0.35
57_L	494_I	1.009	0.35
46_L	49_L	1.008	0.35
242_I	364_L	1.003	0.35
68_L	420_K	1.001	0.35
35_R	154_E	0.998	0.35
256_S	261_N	0.997	0.35
27_K	30_G	0.997	0.35
44_L	320_D	0.996	0.34
70_I	310_F	0.994	0.34
329_I	361_L	0.991	0.34
201_F	327_P	0.991	0.34
297_E	304_I	0.991	0.34
48_P	306_I	0.987	0.34
275_N	494_I	0.986	0.34
57_L	61_I	0.986	0.34
488_A	491_N	0.985	0.34
216_F	474_V	0.980	0.34
407_D	422_V	0.979	0.34
191_N	433_A	0.979	0.34
301_F	305_F	0.979	0.34
39_E	67_L	0.977	0.34
286_L	290_F	0.975	0.33
278_Y	283_P	0.972	0.33
26_I	241_L	0.969	0.33
277_L	487_L	0.968	0.33
361_L	373_A	0.968	0.33
55_I	265_D	0.964	0.33
493_I	496_L	0.960	0.33
110_L	216_F	0.958	0.33
49_L	359_M	0.957	0.32
100_V	397_K	0.957	0.32
361_L	368_I	0.956	0.32
285_I	291_H	0.953	0.32
139_V	241_L	0.952	0.32
300_V	304_I	0.952	0.32
40_Y	361_L	0.951	0.32
57_L	65_F	0.947	0.32
124_N	359_M	0.947	0.32
97_E	411_I	0.945	0.32
25_N	120_E	0.945	0.32
162_G	482_F	0.940	0.32
106_Y	463_Y	0.937	0.31
135_A	165_L	0.929	0.31
197_L	418_L	0.926	0.31
171_V	408_L	0.926	0.31
77_F	80_I	0.925	0.31
74_F	294_L	0.923	0.31
168_I	179_G	0.923	0.31
183_P	491_N	0.922	0.31
32_D	78_F	0.921	0.31
152_A	175_G	0.920	0.31
87_K	99_P	0.920	0.31
283_P	294_L	0.920	0.31
168_I	226_L	0.916	0.30
458_L	463_Y	0.915	0.30
34_E	49_L	0.915	0.30
216_F	220_L	0.914	0.30
231_Y	368_I	0.912	0.30
331_S	439_V	0.911	0.30
175_G	180_I	0.909	0.30
290_F	491_N	0.908	0.30
144_V	219_F	0.907	0.30
51_S	55_I	0.906	0.30
330_L	340_G	0.904	0.30
476_R	481_N	0.902	0.30
48_P	295_E	0.902	0.30
114_N	138_L	0.901	0.30
96_N	200_N	0.900	0.30
49_L	292_L	0.897	0.30
48_P	452_A	0.895	0.29
95_E	164_F	0.894	0.29
39_E	47_M	0.893	0.29
117_K	494_I	0.892	0.29
294_L	305_F	0.888	0.29
33_M	63_P	0.887	0.29
469_I	476_R	0.887	0.29
216_F	219_F	0.886	0.29
284_F	293_S	0.886	0.29
299_L	305_F	0.885	0.29
122_I	182_M	0.884	0.29
312_I	481_N	0.883	0.29
26_I	30_G	0.880	0.29
29_Y	53_I	0.879	0.29
45_F	297_E	0.876	0.29
237_N	494_I	0.876	0.29
229_F	447_M	0.875	0.29
293_S	296_Y	0.874	0.28
165_L	217_M	0.873	0.28
450_I	491_N	0.870	0.28
370_K	449_K	0.868	0.28
245_L	462_L	0.867	0.28
108_N	113_R	0.866	0.28
162_G	357_F	0.865	0.28
248_F	285_I	0.865	0.28
57_L	60_K	0.864	0.28
442_F	448_S	0.864	0.28
132_R	490_M	0.864	0.28
102_L	159_A	0.862	0.28
171_V	365_A	0.862	0.28
442_F	451_R	0.857	0.28
32_D	41_I	0.856	0.28
236_I	335_D	0.855	0.28
280_L	283_P	0.854	0.28
220_L	460_I	0.854	0.28
33_M	48_P	0.853	0.28
119_F	345_S	0.853	0.28
443_A	447_M	0.848	0.27
36_L	56_I	0.846	0.27
26_I	31_D	0.846	0.27
335_D	439_V	0.845	0.27
51_S	289_L	0.845	0.27
212_V	220_L	0.841	0.27
333_I	350_L	0.840	0.27
61_I	292_L	0.839	0.27
147_K	442_F	0.836	0.27
196_G	377_V	0.835	0.27
148_S	333_I	0.835	0.27
438_I	448_S	0.830	0.26
119_F	410_L	0.830	0.26
440_F	444_L	0.829	0.26
265_D	299_L	0.829	0.26
334_A	428_L	0.826	0.26
165_L	227_L	0.825	0.26
65_F	275_N	0.824	0.26
60_K	352_V	0.824	0.26
69_N	465_M	0.822	0.26
62_S	114_N	0.822	0.26
371_N	490_M	0.822	0.26
238_I	276_S	0.822	0.26
99_P	145_L	0.817	0.26
37_R	41_I	0.816	0.26
294_L	297_E	0.816	0.26
476_R	484_L	0.814	0.26
361_L	487_L	0.812	0.26
36_L	39_E	0.811	0.26
158_K	373_A	0.809	0.26
284_F	466_A	0.809	0.26
202_Q	421_K	0.809	0.26
49_L	57_L	0.806	0.25
57_L	288_F	0.806	0.25
112_G	482_F	0.806	0.25
338_K	357_F	0.804	0.25
187_K	452_A	0.803	0.25
131_L	171_V	0.803	0.25
171_V	405_F	0.800	0.25
148_S	412_L	0.799	0.25
259_Q	323_L	0.797	0.25
319_A	380_N	0.796	0.25
52_S	302_Y	0.794	0.25
52_S	78_F	0.793	0.25
323_L	330_L	0.792	0.25
77_F	452_A	0.790	0.25
37_R	40_Y	0.789	0.25
229_F	234_S	0.789	0.25
41_I	45_F	0.786	0.25
53_I	306_I	0.780	0.24
53_I	93_L	0.779	0.24
238_I	277_L	0.778	0.24
277_L	283_P	0.777	0.24
186_L	369_R	0.776	0.24
71_M	82_I	0.774	0.24
141_E	309_S	0.773	0.24
215_L	434_T	0.769	0.24
40_Y	488_A	0.767	0.24
56_I	71_M	0.764	0.24
27_K	31_D	0.757	0.23
47_M	58_Y	0.755	0.23
101_F	131_L	0.755	0.23
71_M	288_F	0.755	0.23
45_F	359_M	0.753	0.23
245_L	278_Y	0.753	0.23
61_I	124_N	0.753	0.23
99_P	340_G	0.753	0.23
319_A	459_I	0.751	0.23
65_F	237_N	0.750	0.23
167_K	256_S	0.747	0.23
459_I	463_Y	0.744	0.23
326_L	394_I	0.742	0.23
41_I	44_L	0.741	0.23
168_I	189_L	0.740	0.23
445_G	495_V	0.740	0.23
122_I	389_E	0.740	0.23
225_I	419_R	0.738	0.23
421_K	459_I	0.738	0.23
61_I	78_F	0.737	0.23
44_L	78_F	0.734	0.22
90_Q	129_K	0.734	0.22
238_I	285_I	0.734	0.22
461_V	464_T	0.733	0.22
70_I	245_L	0.731	0.22
73_V	284_F	0.729	0.22
171_V	180_I	0.728	0.22
148_S	370_K	0.727	0.22
50_I	71_M	0.725	0.22
487_L	495_V	0.724	0.22
331_S	413_Y	0.723	0.22
77_F	282_I	0.721	0.22
369_R	444_L	0.721	0.22
256_S	259_Q	0.720	0.22
123_R	423_L	0.720	0.22
162_G	168_I	0.720	0.22
34_E	38_K	0.719	0.22
69_N	481_N	0.718	0.22
46_L	275_N	0.716	0.22
281_P	285_I	0.715	0.22
53_I	282_I	0.715	0.22
71_M	286_L	0.714	0.22
98_M	363_E	0.712	0.22
242_I	265_D	0.711	0.22
287_V	462_L	0.710	0.21
278_Y	452_A	0.710	0.21
240_E	248_F	0.710	0.21
229_F	441_Y	0.708	0.21
69_N	487_L	0.708	0.21
101_F	132_R	0.706	0.21
237_N	251_I	0.706	0.21
130_G	134_E	0.704	0.21
265_D	288_F	0.704	0.21
126_K	369_R	0.703	0.21
212_V	475_S	0.703	0.21
86_R	278_Y	0.703	0.21
334_A	409_S	0.703	0.21
309_S	483_P	0.702	0.21
223_P	340_G	0.701	0.21
104_F	340_G	0.700	0.21
45_F	183_P	0.700	0.21
73_V	305_F	0.700	0.21
319_A	323_L	0.699	0.21
201_F	229_F	0.699	0.21
101_F	138_L	0.698	0.21
171_V	398_G	0.696	0.21
48_P	77_F	0.693	0.21
204_Y	219_F	0.692	0.21
133_R	284_F	0.690	0.21
282_I	299_L	0.690	0.21
97_E	225_I	0.689	0.21
46_L	285_I	0.689	0.21
59_L	275_N	0.687	0.21
227_L	328_Y	0.686	0.21
276_S	281_P	0.683	0.20
200_N	280_L	0.683	0.20
62_S	186_L	0.683	0.20
52_S	66_L	0.682	0.20
285_I	289_L	0.680	0.20
379_T	383_I	0.680	0.20
459_I	464_T	0.679	0.20
104_F	107_V	0.679	0.20
104_F	393_N	0.678	0.20
160_H	432_L	0.678	0.20
115_L	204_Y	0.678	0.20
390_L	499_G	0.677	0.20
286_L	310_F	0.677	0.20
206_E	456_L	0.676	0.20
35_R	39_E	0.675	0.20
154_E	464_T	0.674	0.20
262_I	477_F	0.674	0.20
276_S	287_V	0.673	0.20
366_A	420_K	0.670	0.20
117_K	342_S	0.670	0.20
300_V	303_S	0.669	0.20
175_G	216_F	0.667	0.20
284_F	291_H	0.667	0.20
279_I	322_I	0.665	0.20
431_I	477_F	0.665	0.20
194_I	418_L	0.664	0.20
67_L	70_I	0.661	0.20
112_G	128_F	0.660	0.20
132_R	467_L	0.660	0.20
145_L	333_I	0.660	0.20
67_L	81_L	0.659	0.20
78_F	289_L	0.657	0.20
50_I	56_I	0.657	0.20
247_L	251_I	0.657	0.20
158_K	265_D	0.653	0.19
40_Y	44_L	0.653	0.19
239_F	459_I	0.652	0.19
219_F	435_I	0.650	0.19
329_I	355_T	0.650	0.19
165_L	232_I	0.650	0.19
91_R	165_L	0.646	0.19
301_F	358_R	0.645	0.19
149_S	218_L	0.644	0.19
282_I	302_Y	0.643	0.19
479_V	484_L	0.643	0.19
476_R	479_V	0.641	0.19
238_I	466_A	0.640	0.19
24_E	53_I	0.638	0.19
28_Y	410_L	0.636	0.19
174_S	217_M	0.636	0.19
346_A	351_N	0.635	0.19
179_G	422_V	0.635	0.19
289_L	306_I	0.635	0.19
62_S	290_F	0.635	0.19
294_L	348_L	0.635	0.19
411_I	432_L	0.634	0.19
28_Y	40_Y	0.633	0.19
62_S	277_L	0.628	0.19
39_E	43_M	0.628	0.19
75_I	290_F	0.628	0.19
111_L	215_L	0.627	0.18
55_I	275_N	0.627	0.18
313_Y	484_L	0.626	0.18
283_P	303_S	0.623	0.18
220_L	423_L	0.622	0.18
419_R	435_I	0.619	0.18
293_S	297_E	0.619	0.18
483_P	491_N	0.618	0.18
306_I	348_L	0.618	0.18
491_N	495_V	0.617	0.18
263_G	350_L	0.616	0.18
439_V	475_S	0.616	0.18
51_S	54_S	0.615	0.18
198_N	369_R	0.615	0.18
47_M	54_S	0.614	0.18
67_L	71_M	0.613	0.18
426_L	429_F	0.613	0.18
58_Y	487_L	0.613	0.18
57_L	275_N	0.612	0.18
152_A	205_V	0.612	0.18
327_P	440_F	0.612	0.18
281_P	292_L	0.611	0.18
24_E	34_E	0.610	0.18
66_L	226_L	0.609	0.18
359_M	491_N	0.607	0.18
69_N	362_G	0.607	0.18
478_T	486_V	0.605	0.18
467_L	470_I	0.604	0.18
279_I	452_A	0.604	0.18
323_L	380_N	0.603	0.18
111_L	167_K	0.600	0.18
109_S	256_S	0.599	0.18
108_N	111_L	0.598	0.17
432_L	474_V	0.597	0.17
62_S	241_L	0.596	0.17
265_D	489_L	0.596	0.17
50_I	74_F	0.595	0.17
387_I	441_Y	0.595	0.17
365_A	408_L	0.595	0.17
73_V	77_F	0.594	0.17
65_F	246_L	0.592	0.17
286_L	289_L	0.591	0.17
109_S	361_L	0.591	0.17
224_M	439_V	0.591	0.17
49_L	487_L	0.590	0.17
378_R	484_L	0.588	0.17
70_I	489_L	0.587	0.17
220_L	263_G	0.587	0.17
237_N	248_F	0.587	0.17
111_L	339_I	0.586	0.17
56_I	290_F	0.586	0.17
24_E	285_I	0.585	0.17
426_L	436_T	0.584	0.17
329_I	383_I	0.583	0.17
281_P	284_F	0.582	0.17
244_P	374_I	0.582	0.17
418_L	422_V	0.581	0.17
198_N	494_I	0.579	0.17
122_I	135_A	0.575	0.17
186_L	410_L	0.574	0.17
31_D	403_Y	0.574	0.17
323_L	374_I	0.573	0.17
246_L	377_V	0.573	0.17
70_I	74_F	0.572	0.17
293_S	300_V	0.572	0.17
140_K	145_L	0.572	0.17
52_S	56_I	0.571	0.17
197_L	201_F	0.571	0.17
133_R	206_E	0.570	0.17
47_M	50_I	0.569	0.17
59_L	310_F	0.567	0.16
311_F	390_L	0.567	0.16
41_I	245_L	0.566	0.16
150_F	425_N	0.566	0.16
460_I	492_L	0.566	0.16
334_A	419_R	0.566	0.16
309_S	398_G	0.566	0.16
161_R	485_L	0.565	0.16
123_R	286_L	0.564	0.16
36_L	44_L	0.563	0.16
337_L	340_G	0.563	0.16
36_L	80_I	0.562	0.16
235_S	361_L	0.562	0.16
41_I	142_V	0.559	0.16
169_Y	387_I	0.558	0.16
102_L	301_F	0.558	0.16
96_N	446_I	0.558	0.16
34_E	67_L	0.557	0.16
67_L	314_R	0.555	0.16
69_N	289_L	0.555	0.16
204_Y	461_V	0.554	0.16
70_I	280_L	0.554	0.16
92_K	129_K	0.553	0.16
77_F	123_R	0.551	0.16
55_I	352_V	0.550	0.16
179_G	189_L	0.549	0.16
347_I	452_A	0.548	0.16
91_R	300_V	0.547	0.16
149_S	373_A	0.547	0.16
48_P	358_R	0.546	0.16
436_T	444_L	0.545	0.16
352_V	376_N	0.544	0.16
110_L	405_F	0.544	0.16
45_F	290_F	0.543	0.16
50_I	285_I	0.543	0.16
141_E	330_L	0.543	0.16
147_K	373_A	0.543	0.16
223_P	496_L	0.542	0.16
243_F	452_A	0.541	0.16
279_I	310_F	0.541	0.16
119_F	328_Y	0.540	0.16
302_Y	305_F	0.540	0.16
133_R	136_M	0.539	0.16
318_V	469_I	0.539	0.16
178_I	342_S	0.538	0.16
36_L	45_F	0.538	0.16
135_A	433_A	0.537	0.16
241_L	244_P	0.536	0.16
196_G	432_L	0.535	0.16
338_K	406_K	0.534	0.15
275_N	289_L	0.534	0.15
224_M	472_A	0.532	0.15
215_L	422_V	0.531	0.15
256_S	263_G	0.529	0.15
335_D	338_K	0.527	0.15
241_L	291_H	0.524	0.15
56_I	462_L	0.524	0.15
275_N	291_H	0.521	0.15
404_T	407_D	0.521	0.15
265_D	304_I	0.520	0.15
436_T	473_K	0.520	0.15
129_K	134_E	0.519	0.15
283_P	305_F	0.519	0.15
153_M	295_E	0.519	0.15
288_F	369_R	0.519	0.15
213_E	468_S	0.518	0.15
108_N	420_K	0.516	0.15
73_V	282_I	0.516	0.15
296_Y	300_V	0.513	0.15
354_N	358_R	0.513	0.15
376_N	492_L	0.509	0.15
98_M	108_N	0.509	0.15
168_I	215_L	0.509	0.15
189_L	329_I	0.509	0.15
117_K	242_I	0.508	0.15
55_I	183_P	0.508	0.15
49_L	86_R	0.508	0.15
178_I	228_A	0.507	0.15
65_F	359_M	0.504	0.15
228_A	392_E	0.503	0.15
278_Y	284_F	0.503	0.15
243_F	468_S	0.503	0.15
177_S	342_S	0.502	0.15
333_I	426_L	0.501	0.15
57_L	498_F	0.500	0.14
242_I	284_F	0.500	0.14

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2whnA	1	0.2134	98	0.916	Contact Map
3c1qA	2	0.2332	97.8	0.92	Contact Map
4hhxA	1	0.1957	97.6	0.923	Contact Map
1rh1A	1	0.1976	12.3	0.974	Contact Map
3aqpA	1	0.1581	10.5	0.975	Contact Map
3w9iA	3	0.166	8.3	0.976	Contact Map
3tweA	2	0.0514	6.9	0.977	Contact Map
2lv7A	1	0.1858	6.6	0.977	Contact Map
2o3lA	1	0.1443	6.3	0.978	Contact Map
3fx7A	2	0.1581	6.1	0.978	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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