Q7LXX6 - SULSO - GREMLIN Contacts

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Q7LXX6 - Type II secretion system protein, virB homolog (GspE-1)

UniProt:	Q7LXX6	Sequences: MSIFFLNNGIMNILQEYSVLNAKVIIYEENGIGYYKVNEPNLDQNEIEILNSILEYIYSTPSVPNIEETVVKILKNKGISDQGIIEKIIYYLRKRIGYDELTVPLADPYVEEIECKGFSYPVTVVHRIVTRFPRLYTNIILEQEDHVLKVIEKLANKADKPVSIAKPYLEFSLPEGHRVAATVSREVSLPGSTFDIRKFPLKPISPISLIKNESISSLMLAYIWFLLDYKPFFLIIGSTGSGKTTLLNSILSMINPFFKVITIEDTPEINIIHDNWIRFFARQSISSQFEVSLMDLAKLSLRYRPDYLVIGEIRGKEIEALVHASASGHGSLATFHAGNPHEALTRLLSLLNKDVAKLFLQNLWGIIVLGTLRDRNGNIRRIIRSIYEIVYTRGKLRFRPVLRWSFSSNTFMPNNIDDLIKRSYRISYISKTYEIPISEITKEISNRVKTLNNFVSNNILDLEEFSVYLKKISQGDKVETKAI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	483 (432)
Sequences:	5023 (3581)
Seq/√Len:	172.3

ECOLI - GSPE HOFB YGGR
BACSU - COMGA
HALSA - Q9HQY3 Q9HR79
SULSO - Q7LXX6 Q97WB7 Q97VE6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
423_S	449_K	4.656	1.00
375_R	399_R	4.595	1.00
222_Y	250_I	3.989	1.00
225_F	365_G	3.863	1.00
381_R	400_P	3.698	1.00
429_I	443_E	3.691	1.00
151_I	194_F	3.541	1.00
193_T	259_K	3.508	1.00
339_N	342_E	3.354	1.00
380_R	397_R	3.310	1.00
258_F	307_Y	3.146	1.00
382_I	395_K	3.125	1.00
378_N	404_W	3.124	1.00
223_I	253_M	3.048	1.00
381_R	398_F	2.944	1.00
234_L	333_A	2.812	1.00
261_I	300_S	2.781	1.00
429_I	434_E	2.725	1.00
375_R	468_Y	2.702	1.00
458_N	472_I	2.528	1.00
383_I	396_L	2.509	1.00
263_I	296_L	2.480	1.00
374_D	414_N	2.473	1.00
447_R	456_S	2.384	1.00
443_E	449_K	2.379	1.00
189_L	267_P	2.363	1.00
236_I	335_F	2.355	1.00
423_S	443_E	2.339	1.00
383_I	398_F	2.317	1.00
375_R	380_R	2.282	1.00
177_H	200_P	2.279	1.00
219_M	223_I	2.270	1.00
367_I	419_L	2.264	1.00
226_L	250_I	2.263	1.00
313_I	321_L	2.257	1.00
167_P	289_F	2.238	1.00
66_I	74_L	2.228	1.00
422_R	430_S	2.185	1.00
122_V	147_V	2.183	1.00
181_A	196_I	2.158	1.00
443_E	448_V	2.133	1.00
426_I	440_I	2.131	1.00
386_I	390_V	2.126	1.00
224_W	421_K	2.114	1.00
385_S	388_E	2.102	1.00
436_P	439_E	2.091	1.00
425_R	449_K	2.075	1.00
452_N	460_L	2.062	1.00
414_N	466_S	2.055	1.00
186_E	277_I	2.044	1.00
457_N	461_D	2.016	1.00
101_L	150_V	1.958	1.00
460_L	464_E	1.922	1.00
399_R	468_Y	1.922	1.00
70_V	74_L	1.917	1.00
109_Y	411_F	1.907	1.00
137_T	140_I	1.905	1.00
193_T	275_N	1.895	1.00
339_N	441_T	1.851	1.00
217_S	452_N	1.842	1.00
341_H	420_I	1.837	1.00
446_N	450_T	1.815	1.00
69_T	74_L	1.787	1.00
218_L	417_D	1.786	1.00
263_I	300_S	1.785	1.00
292_S	295_D	1.785	1.00
280_F	288_Q	1.783	1.00
134_R	474_Q	1.776	1.00
428_Y	432_T	1.766	1.00
160_K	185_R	1.762	1.00
218_L	419_L	1.726	1.00
254_I	307_Y	1.718	1.00
459_I	463_E	1.715	1.00
158_A	183_V	1.697	1.00
121_P	140_I	1.690	1.00
239_T	305_P	1.686	1.00
184_S	303_Y	1.672	1.00
185_R	194_F	1.646	1.00
181_A	198_K	1.640	1.00
216_S	220_L	1.636	1.00
215_I	218_L	1.635	1.00
39_E	42_L	1.634	1.00
199_F	269_I	1.628	1.00
378_N	411_F	1.623	1.00
49_I	57_I	1.614	1.00
188_S	275_N	1.610	1.00
228_D	364_W	1.588	1.00
32_I	58_Y	1.588	1.00
344_L	363_L	1.584	1.00
208_S	211_K	1.583	1.00
462_L	472_I	1.568	1.00
434_E	439_E	1.562	1.00
402_L	405_S	1.551	1.00
414_N	461_D	1.539	1.00
461_D	466_S	1.513	1.00
35_Y	49_I	1.499	1.00
396_L	462_L	1.483	1.00
43_D	47_I	1.478	1.00
348_L	359_F	1.473	1.00
425_R	443_E	1.456	1.00
376_N	379_I	1.452	1.00
115_C	122_V	1.449	1.00
218_L	457_N	1.443	1.00
154_L	183_V	1.441	1.00
62_S	65_N	1.435	1.00
102_T	106_A	1.426	1.00
420_I	451_L	1.420	1.00
218_L	221_A	1.414	1.00
34_Y	60_T	1.414	1.00
233_F	330_G	1.405	1.00
453_N	456_S	1.395	1.00
442_K	448_V	1.393	1.00
376_N	405_S	1.392	1.00
379_I	405_S	1.388	1.00
66_I	69_T	1.383	1.00
424_Y	427_S	1.382	1.00
239_T	329_H	1.374	1.00
379_I	402_L	1.373	1.00
134_R	373_R	1.371	1.00
217_S	221_A	1.361	1.00
116_K	125_V	1.361	1.00
439_E	442_K	1.360	1.00
246_L	369_L	1.360	1.00
255_N	260_V	1.356	1.00
375_R	400_P	1.349	1.00
387_Y	390_V	1.348	1.00
382_I	397_R	1.344	1.00
123_T	137_T	1.331	1.00
425_R	448_V	1.331	1.00
280_F	289_F	1.328	1.00
376_N	402_L	1.326	1.00
375_R	397_R	1.326	1.00
319_E	323_H	1.312	1.00
277_I	300_S	1.312	1.00
234_L	313_I	1.308	1.00
296_L	300_S	1.305	1.00
214_S	417_D	1.300	1.00
377_G	380_R	1.294	1.00
102_T	105_L	1.283	1.00
398_F	470_K	1.274	1.00
227_L	253_M	1.262	1.00
126_H	138_N	1.262	1.00
220_L	224_W	1.260	1.00
46_E	59_S	1.260	1.00
214_S	222_Y	1.259	1.00
233_F	365_G	1.247	1.00
69_T	72_K	1.227	1.00
224_W	228_D	1.226	1.00
66_I	70_V	1.224	1.00
193_T	261_I	1.212	1.00
302_R	314_R	1.202	1.00
318_I	353_K	1.195	1.00
221_A	421_K	1.187	1.00
225_F	419_L	1.184	1.00
354_D	357_K	1.183	1.00
348_L	356_A	1.181	1.00
210_I	223_I	1.177	1.00
37_V	59_S	1.173	1.00
313_I	333_A	1.166	1.00
335_F	343_A	1.161	1.00
386_I	389_I	1.155	1.00
254_I	332_L	1.154	1.00
214_S	246_L	1.154	1.00
27_Y	34_Y	1.151	1.00
36_K	40_P	1.144	1.00
366_I	420_I	1.141	1.00
318_I	347_L	1.141	1.00
416_I	458_N	1.140	1.00
432_T	439_E	1.129	1.00
210_I	219_M	1.122	1.00
410_T	468_Y	1.118	1.00
33_G	53_I	1.113	1.00
173_L	181_A	1.107	1.00
410_T	467_V	1.096	1.00
297_A	320_A	1.094	1.00
48_E	51_N	1.091	1.00
322_V	353_K	1.080	1.00
323_H	326_A	1.076	1.00
53_I	57_I	1.071	1.00
341_H	440_I	1.069	1.00
368_V	454_F	1.063	1.00
66_I	73_I	1.061	1.00
218_L	367_I	1.056	1.00
308_L	324_A	1.055	1.00
100_E	104_P	1.047	0.99
341_H	441_T	1.043	0.99
316_K	319_E	1.041	0.99
61_P	65_N	1.039	0.99
236_I	337_A	1.030	0.99
447_R	451_L	1.026	0.99
67_E	71_V	1.020	0.99
463_E	466_S	1.016	0.99
459_I	462_L	1.016	0.99
61_P	64_P	1.015	0.99
426_I	443_E	1.014	0.99
446_N	451_L	1.010	0.99
50_L	56_Y	1.005	0.99
215_I	460_L	1.001	0.99
300_S	308_L	0.995	0.99
235_I	246_L	0.994	0.99
215_I	464_E	0.990	0.99
401_V	405_S	0.987	0.99
323_H	349_S	0.986	0.99
326_A	358_L	0.982	0.99
209_L	249_S	0.979	0.99
385_S	390_V	0.979	0.99
143_Q	147_V	0.978	0.99
157_K	173_L	0.977	0.99
312_E	336_H	0.976	0.99
178_R	201_L	0.975	0.99
179_V	198_K	0.972	0.99
363_L	366_I	0.968	0.99
232_F	331_S	0.968	0.99
33_G	40_P	0.966	0.99
385_S	389_I	0.965	0.99
462_L	469_L	0.964	0.99
459_I	469_L	0.963	0.99
193_T	303_Y	0.959	0.99
294_M	317_E	0.956	0.99
391_Y	394_G	0.954	0.99
461_D	464_E	0.952	0.99
298_K	317_E	0.947	0.99
96_I	99_D	0.945	0.99
441_T	447_R	0.943	0.99
28_E	34_Y	0.938	0.99
238_S	370_G	0.937	0.99
372_L	467_V	0.937	0.99
50_L	57_I	0.935	0.99
37_V	42_L	0.930	0.99
46_E	50_L	0.929	0.99
42_L	45_N	0.929	0.99
98_Y	102_T	0.926	0.99
32_I	56_Y	0.922	0.99
343_A	366_I	0.917	0.99
460_L	463_E	0.912	0.99
69_T	73_I	0.910	0.99
70_V	73_I	0.901	0.98
76_N	80_S	0.899	0.98
215_I	461_D	0.896	0.98
167_P	291_V	0.896	0.98
261_I	277_I	0.895	0.98
255_N	273_H	0.891	0.98
246_L	367_I	0.890	0.98
179_V	200_P	0.890	0.98
241_S	369_L	0.890	0.98
77_K	80_S	0.889	0.98
153_K	157_K	0.885	0.98
359_F	363_L	0.883	0.98
254_I	260_V	0.883	0.98
373_R	471_K	0.878	0.98
341_H	437_I	0.877	0.98
428_Y	442_K	0.877	0.98
68_E	72_K	0.875	0.98
33_G	36_K	0.874	0.98
31_G	55_E	0.874	0.98
452_N	456_S	0.873	0.98
267_P	278_R	0.873	0.98
341_H	451_L	0.869	0.98
170_E	184_S	0.868	0.98
348_L	433_Y	0.868	0.98
121_P	272_I	0.867	0.98
247_L	309_V	0.863	0.98
230_K	339_N	0.863	0.98
67_E	70_V	0.862	0.98
447_R	453_N	0.861	0.98
396_L	399_R	0.860	0.98
114_E	195_D	0.855	0.98
268_E	336_H	0.855	0.98
433_Y	436_P	0.855	0.98
53_I	56_Y	0.855	0.98
215_I	457_N	0.855	0.98
226_L	233_F	0.853	0.98
230_K	364_W	0.852	0.98
429_I	439_E	0.851	0.98
214_S	415_N	0.849	0.98
158_A	173_L	0.847	0.98
55_E	59_S	0.845	0.98
74_L	81_D	0.844	0.98
155_A	192_S	0.844	0.98
247_L	332_L	0.843	0.98
395_K	398_F	0.843	0.98
118_F	123_T	0.843	0.98
277_I	296_L	0.839	0.98
236_I	343_A	0.839	0.98
243_K	312_E	0.838	0.98
239_T	327_S	0.836	0.97
222_Y	419_L	0.833	0.97
225_F	364_W	0.831	0.97
236_I	368_V	0.831	0.97
209_L	223_I	0.831	0.97
47_I	50_L	0.829	0.97
344_L	430_S	0.828	0.97
422_R	426_I	0.828	0.97
243_K	336_H	0.826	0.97
38_N	41_N	0.824	0.97
259_K	275_N	0.823	0.97
42_L	46_E	0.823	0.97
259_K	303_Y	0.822	0.97
239_T	306_D	0.821	0.97
301_L	324_A	0.821	0.97
261_I	275_N	0.818	0.97
468_Y	471_K	0.817	0.97
291_V	296_L	0.812	0.97
360_L	431_K	0.811	0.97
374_D	466_S	0.811	0.97
226_L	332_L	0.809	0.97
108_P	406_F	0.804	0.97
37_V	40_P	0.802	0.97
467_V	471_K	0.802	0.97
322_V	358_L	0.799	0.97
457_N	460_L	0.795	0.97
379_I	401_V	0.795	0.97
221_A	224_W	0.794	0.97
29_E	55_E	0.793	0.97
426_I	446_N	0.789	0.96
31_G	34_Y	0.785	0.96
183_V	196_I	0.785	0.96
105_L	181_A	0.784	0.96
442_K	447_R	0.783	0.96
101_L	154_L	0.782	0.96
27_Y	30_N	0.778	0.96
50_L	54_L	0.778	0.96
68_E	74_L	0.777	0.96
446_N	449_K	0.775	0.96
313_I	318_I	0.774	0.96
155_A	169_L	0.774	0.96
225_F	233_F	0.773	0.96
447_R	450_T	0.769	0.96
111_E	195_D	0.767	0.96
345_T	437_I	0.766	0.96
66_I	72_K	0.765	0.96
416_I	475_G	0.764	0.96
268_E	312_E	0.764	0.96
263_I	279_F	0.762	0.96
37_V	46_E	0.762	0.96
232_F	363_L	0.762	0.96
305_P	329_H	0.761	0.96
160_K	184_S	0.760	0.96
302_R	312_E	0.757	0.95
36_K	62_S	0.754	0.95
127_R	304_R	0.753	0.95
27_Y	60_T	0.752	0.95
425_R	429_I	0.751	0.95
76_N	79_I	0.750	0.95
385_S	400_P	0.744	0.95
184_S	195_D	0.743	0.95
254_I	258_F	0.743	0.95
44_Q	48_E	0.741	0.95
90_Y	93_R	0.741	0.95
302_R	336_H	0.741	0.95
337_A	340_P	0.740	0.95
195_D	303_Y	0.739	0.95
329_H	346_R	0.738	0.95
232_F	321_L	0.736	0.95
29_E	32_I	0.734	0.95
339_N	454_F	0.733	0.95
290_E	295_D	0.733	0.95
31_G	35_Y	0.732	0.95
265_D	278_R	0.728	0.94
422_R	427_S	0.726	0.94
424_Y	442_K	0.725	0.94
108_P	136_Y	0.724	0.94
35_Y	40_P	0.722	0.94
36_K	60_T	0.719	0.94
118_F	121_P	0.717	0.94
314_R	336_H	0.717	0.94
167_P	295_D	0.717	0.94
372_L	416_I	0.716	0.94
174_P	178_R	0.714	0.94
469_L	473_S	0.712	0.94
218_L	452_N	0.710	0.94
384_R	395_K	0.710	0.94
438_S	442_K	0.709	0.94
251_L	309_V	0.708	0.94
104_P	124_V	0.708	0.94
420_I	426_I	0.707	0.94
33_G	55_E	0.703	0.93
421_K	451_L	0.703	0.93
190_P	278_R	0.702	0.93
356_A	433_Y	0.702	0.93
434_E	440_I	0.701	0.93
252_S	255_N	0.700	0.93
396_L	463_E	0.700	0.93
424_Y	438_S	0.700	0.93
42_L	48_E	0.698	0.93
61_P	66_I	0.696	0.93
160_K	194_F	0.695	0.93
37_V	43_D	0.693	0.93
298_K	315_G	0.692	0.93
189_L	270_N	0.692	0.93
316_K	352_N	0.690	0.93
235_I	247_L	0.689	0.93
37_V	45_N	0.689	0.93
425_R	428_Y	0.688	0.93
420_I	440_I	0.688	0.93
397_R	400_P	0.688	0.93
114_E	304_R	0.688	0.93
217_S	460_L	0.685	0.92
235_I	367_I	0.685	0.92
42_L	47_I	0.684	0.92
209_L	219_M	0.684	0.92
71_V	74_L	0.683	0.92
161_P	288_Q	0.682	0.92
300_S	310_I	0.682	0.92
74_L	77_K	0.679	0.92
162_V	166_K	0.679	0.92
428_Y	438_S	0.678	0.92
32_I	38_N	0.677	0.92
376_N	401_V	0.677	0.92
325_S	331_S	0.677	0.92
319_E	354_D	0.676	0.92
455_V	459_I	0.675	0.92
184_S	299_L	0.675	0.92
115_C	147_V	0.674	0.92
34_Y	58_Y	0.672	0.92
30_N	33_G	0.668	0.91
244_T	269_I	0.668	0.91
458_N	467_V	0.667	0.91
197_R	336_H	0.666	0.91
372_L	414_N	0.666	0.91
204_I	208_S	0.665	0.91
99_D	103_V	0.662	0.91
45_N	49_I	0.662	0.91
116_K	259_K	0.662	0.91
103_V	107_D	0.661	0.91
311_G	336_H	0.661	0.91
182_T	187_V	0.660	0.91
154_L	196_I	0.660	0.91
197_R	312_E	0.660	0.91
88_I	92_L	0.658	0.91
287_S	291_V	0.656	0.91
244_T	271_I	0.655	0.91
134_R	257_F	0.654	0.91
40_P	43_D	0.653	0.91
119_S	190_P	0.653	0.91
154_L	194_F	0.653	0.91
439_E	443_E	0.651	0.90
263_I	277_I	0.647	0.90
365_G	419_L	0.646	0.90
360_L	364_W	0.646	0.90
322_V	326_A	0.645	0.90
234_L	335_F	0.643	0.90
136_Y	406_F	0.642	0.90
48_E	52_S	0.641	0.90
39_E	45_N	0.640	0.90
292_S	317_E	0.639	0.90
443_E	446_N	0.636	0.89
186_E	303_Y	0.634	0.89
28_E	31_G	0.633	0.89
120_Y	272_I	0.633	0.89
208_S	253_M	0.633	0.89
40_P	60_T	0.631	0.89
458_N	461_D	0.630	0.89
84_I	87_K	0.630	0.89
94_K	104_P	0.630	0.89
30_N	58_Y	0.630	0.89
381_R	384_R	0.629	0.89
210_I	216_S	0.628	0.89
141_L	150_V	0.628	0.89
98_Y	104_P	0.627	0.89
287_S	292_S	0.627	0.89
116_K	165_A	0.626	0.89
96_I	104_P	0.625	0.89
334_T	337_A	0.624	0.88
197_R	243_K	0.622	0.88
232_F	322_V	0.621	0.88
98_Y	153_K	0.620	0.88
225_F	421_K	0.619	0.88
378_N	469_L	0.616	0.88
97_G	102_T	0.616	0.88
243_K	268_E	0.612	0.87
75_K	79_I	0.612	0.87
47_I	51_N	0.609	0.87
375_R	381_R	0.607	0.87
49_I	53_I	0.607	0.87
427_S	431_K	0.607	0.87
405_S	409_N	0.607	0.87
173_L	183_V	0.606	0.87
180_A	201_L	0.606	0.87
455_V	458_N	0.605	0.87
217_S	220_L	0.604	0.87
397_R	401_V	0.604	0.87
201_L	269_I	0.603	0.87
29_E	33_G	0.603	0.87
216_S	219_M	0.601	0.87
167_P	290_E	0.600	0.86
421_K	424_Y	0.596	0.86
340_P	420_I	0.595	0.86
263_I	320_A	0.595	0.86
244_T	248_N	0.595	0.86
308_L	329_H	0.595	0.86
100_E	141_L	0.594	0.86
405_S	412_M	0.594	0.86
86_E	89_I	0.593	0.86
68_E	71_V	0.593	0.86
243_K	302_R	0.593	0.86
147_V	151_I	0.592	0.86
67_E	74_L	0.592	0.86
74_L	82_Q	0.592	0.86
425_R	432_T	0.592	0.86
221_A	419_L	0.591	0.86
197_R	268_E	0.591	0.86
400_P	403_R	0.590	0.86
156_N	162_V	0.590	0.86
66_I	76_N	0.588	0.85
326_A	362_N	0.587	0.85
112_E	336_H	0.587	0.85
233_F	367_I	0.587	0.85
73_I	76_N	0.586	0.85
37_V	44_Q	0.585	0.85
456_S	460_L	0.585	0.85
35_Y	41_N	0.584	0.85
100_E	150_V	0.584	0.85
467_V	472_I	0.584	0.85
327_S	346_R	0.583	0.85
170_E	302_R	0.582	0.85
297_A	300_S	0.581	0.85
35_Y	59_S	0.580	0.85
212_N	417_D	0.580	0.85
112_E	293_L	0.579	0.84
30_N	34_Y	0.579	0.84
104_P	107_D	0.577	0.84
416_I	461_D	0.576	0.84
268_E	314_R	0.575	0.84
248_N	271_I	0.573	0.84
311_G	314_R	0.572	0.84
156_N	259_K	0.570	0.84
56_Y	59_S	0.570	0.84
193_T	277_I	0.570	0.84
36_K	41_N	0.568	0.83
132_F	373_R	0.568	0.83
342_E	345_T	0.568	0.83
94_K	99_D	0.566	0.83
289_F	295_D	0.565	0.83
104_P	139_I	0.564	0.83
147_V	194_F	0.564	0.83
168_Y	299_L	0.564	0.83
112_E	243_K	0.563	0.83
151_I	192_S	0.563	0.83
29_E	34_Y	0.562	0.83
447_R	452_N	0.562	0.83
177_H	202_K	0.561	0.83
49_I	54_L	0.559	0.82
309_V	333_A	0.558	0.82
137_T	256_P	0.556	0.82
161_P	166_K	0.555	0.82
122_V	151_I	0.554	0.82
232_F	364_W	0.554	0.82
96_I	102_T	0.554	0.82
455_V	473_S	0.552	0.82
112_E	302_R	0.552	0.82
39_E	47_I	0.551	0.81
170_E	298_K	0.551	0.81
373_R	410_T	0.550	0.81
245_T	269_I	0.548	0.81
42_L	50_L	0.547	0.81
51_N	54_L	0.545	0.81
377_G	404_W	0.545	0.81
115_C	194_F	0.545	0.81
104_P	115_C	0.545	0.81
434_E	443_E	0.544	0.81
232_F	365_G	0.544	0.81
43_D	46_E	0.544	0.81
46_E	57_I	0.544	0.81
170_E	314_R	0.543	0.81
112_E	304_R	0.541	0.80
239_T	346_R	0.541	0.80
459_I	472_I	0.541	0.80
112_E	312_E	0.541	0.80
100_E	103_V	0.537	0.80
95_R	104_P	0.537	0.80
54_L	57_I	0.535	0.80
104_P	113_I	0.535	0.80
360_L	430_S	0.534	0.79
45_N	48_E	0.534	0.79
378_N	403_R	0.534	0.79
240_G	329_H	0.534	0.79
319_E	349_S	0.533	0.79
54_L	58_Y	0.533	0.79
456_S	459_I	0.532	0.79
396_L	407_S	0.532	0.79
243_K	314_R	0.531	0.79
70_V	76_N	0.531	0.79
101_L	105_L	0.530	0.79
341_H	345_T	0.530	0.79
431_K	437_I	0.530	0.79
275_N	303_Y	0.530	0.79
220_L	227_L	0.529	0.79
215_I	452_N	0.529	0.79
95_R	100_E	0.529	0.79
172_S	180_A	0.529	0.79
46_E	51_N	0.529	0.79
249_S	253_M	0.529	0.79
230_K	245_T	0.528	0.79
302_R	311_G	0.528	0.79
114_E	293_L	0.527	0.79
94_K	102_T	0.526	0.78
98_Y	101_L	0.526	0.78
232_F	325_S	0.526	0.78
321_L	331_S	0.526	0.78
237_G	243_K	0.525	0.78
186_E	300_S	0.525	0.78
101_L	104_P	0.524	0.78
271_I	274_D	0.524	0.78
172_S	323_H	0.523	0.78
455_V	472_I	0.522	0.78
112_E	195_D	0.522	0.78
448_V	451_L	0.522	0.78
32_I	55_E	0.521	0.78
240_G	268_E	0.520	0.78
222_Y	226_L	0.519	0.78
116_K	123_T	0.517	0.77
431_K	438_S	0.515	0.77
416_I	472_I	0.514	0.77
260_V	274_D	0.514	0.77
36_K	39_E	0.514	0.77
437_I	440_I	0.513	0.77
49_I	52_S	0.512	0.77
138_N	178_R	0.512	0.77
200_P	203_P	0.511	0.76
339_N	418_D	0.511	0.76
471_K	474_Q	0.510	0.76
37_V	41_N	0.509	0.76
305_P	346_R	0.509	0.76
325_S	362_N	0.508	0.76
276_W	369_L	0.507	0.76
402_L	409_N	0.507	0.76
115_C	196_I	0.507	0.76
30_N	81_D	0.506	0.76
152_E	162_V	0.506	0.76
437_I	441_T	0.506	0.76
37_V	57_I	0.505	0.76
203_P	208_S	0.505	0.76
302_R	334_T	0.504	0.75
268_E	346_R	0.504	0.75
71_V	75_K	0.504	0.75
34_Y	38_N	0.503	0.75
170_E	299_L	0.503	0.75
98_Y	107_D	0.502	0.75
58_Y	65_N	0.502	0.75
166_K	289_F	0.502	0.75
420_I	450_T	0.501	0.75
186_E	299_L	0.501	0.75
466_S	472_I	0.501	0.75
240_G	336_H	0.500	0.75
114_E	266_T	0.500	0.75
237_G	311_G	0.500	0.75
38_N	63_V	0.500	0.75

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4phtA	1	0.8758	100	0.357	Contact Map
4ksrA	3	0.7329	100	0.426	Contact Map
2oap1	3	0.9441	100	0.449	Contact Map
1p9rA	1	0.7598	100	0.45	Contact Map
4ihqA	3	0.9731	100	0.47	Contact Map
2ewvA	3	0.6832	100	0.561	Contact Map
3jvvA	3	0.6729	100	0.575	Contact Map
2gzaA	3	0.6232	100	0.633	Contact Map
2eyuA	1	0.4845	100	0.68	Contact Map
4bloA	4	0.5424	100	0.755	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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