GREMLIN Database
Q7LXR0 - Ribosomal protein S6 modification protein (RimK-2)
UniProt: Q7LXR0 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 282 (263)
Sequences: 30117 (17703)
Seq/√Len: 1091.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
103_D168_E3.9831.00
220_E224_K3.1871.00
142_D145_E3.1161.00
241_H245_G3.0271.00
118_E143_V2.9271.00
114_M147_K2.6561.00
94_L248_I2.4711.00
122_F143_V2.4711.00
105_I119_Q2.4691.00
94_L225_S2.2981.00
100_P245_G2.2971.00
109_S112_A2.2471.00
65_A82_G2.2421.00
223_V227_K2.2371.00
91_Y167_Q2.1651.00
88_I106_I2.1581.00
143_V147_K2.0911.00
139_L169_Y1.9911.00
116_A120_M1.9011.00
141_R145_E1.8461.00
88_I92_S1.8341.00
95_F103_D1.8271.00
89_L92_S1.8251.00
65_A69_A1.8021.00
92_S96_K1.7861.00
156_L160_A1.7741.00
86_D129_P1.7651.00
217_N245_G1.7501.00
66_I70_A1.7471.00
114_M143_V1.7421.00
90_T94_L1.7331.00
177_I240_E1.7131.00
226_V234_V1.6941.00
97_H228_L1.6801.00
270_E274_D1.6711.00
92_S95_F1.6691.00
83_T89_L1.6681.00
83_T93_K1.6571.00
43_A70_A1.6431.00
147_K151_E1.6311.00
21_L28_Y1.6161.00
116_A119_Q1.6081.00
105_I116_A1.6071.00
20_A23_E1.5981.00
50_G72_V1.5891.00
96_K228_L1.5871.00
117_Y122_F1.5741.00
221_L246_Y1.5681.00
217_N221_L1.5441.00
221_L224_K1.5361.00
267_N270_E1.5271.00
82_G89_L1.5051.00
100_P221_L1.5031.00
240_E246_Y1.4911.00
224_K228_L1.4801.00
224_K227_K1.4741.00
77_S80_A1.4711.00
125_I139_L1.4671.00
157_N160_A1.4441.00
108_A163_V1.4331.00
138_S152_H1.4251.00
88_I129_P1.4171.00
124_L166_I1.4161.00
24_R274_D1.4111.00
114_M118_E1.4091.00
60_A85_G1.3981.00
148_T152_H1.3871.00
175_R191_A1.3841.00
239_L249_N1.3831.00
199_W202_N1.3811.00
236_I251_L1.3781.00
93_K228_L1.3741.00
99_I248_I1.3701.00
125_I169_Y1.3651.00
129_P163_V1.3601.00
93_K96_K1.3601.00
168_E247_V1.3401.00
79_D83_T1.3391.00
66_I69_A1.3311.00
115_K119_Q1.3291.00
24_R270_E1.3291.00
217_N220_E1.3241.00
95_F101_I1.3221.00
271_K274_D1.3201.00
91_Y101_I1.3151.00
241_H247_V1.3091.00
125_I137_V1.3061.00
219_R223_V1.3031.00
182_I271_K1.3011.00
182_I233_F1.2891.00
103_D119_Q1.2791.00
110_P114_M1.2771.00
141_R171_K1.2741.00
68_E78_T1.2741.00
225_S228_L1.2701.00
110_P151_E1.2531.00
93_K97_H1.2441.00
23_E270_E1.2441.00
20_A270_E1.2331.00
181_V226_V1.2151.00
122_F142_D1.2131.00
110_P147_K1.2101.00
179_C218_I1.1941.00
29_D47_Y1.1911.00
104_S167_Q1.1891.00
26_I273_V1.1821.00
18_I22_N1.1821.00
215_D219_R1.1821.00
216_D220_E1.1791.00
19_K23_E1.1771.00
106_I163_V1.1671.00
175_R240_E1.1551.00
179_C222_A1.1501.00
120_M124_L1.1501.00
108_A112_A1.1441.00
225_S229_V1.1371.00
68_E77_S1.1361.00
68_E74_T1.1351.00
184_D187_L1.1311.00
140_I149_I1.1281.00
100_P247_V1.1221.00
67_L74_T1.1221.00
181_V222_A1.1121.00
65_A78_T1.1051.00
197_N201_A1.1041.00
216_D219_R1.0971.00
84_C229_V1.0951.00
188_G192_R1.0921.00
266_I271_K1.0821.00
111_D114_M1.0801.00
170_I247_V1.0781.00
92_S104_S1.0761.00
181_V234_V1.0711.00
17_I51_I1.0611.00
138_S149_I1.0581.00
103_D120_M1.0531.00
88_I163_V1.0491.00
208_N211_P1.0471.00
115_K118_E1.0401.00
182_I275_H1.0361.00
170_I249_N1.0331.00
79_D82_G1.0331.00
183_G186_L1.0311.00
102_P170_I1.0281.00
67_L72_V1.0271.00
168_E241_H1.0261.00
214_L217_N1.0241.00
122_F146_G1.0171.00
200_R204_A1.0161.00
84_C251_L1.0091.00
23_E269_A1.0031.00
124_L140_I1.0011.00
117_Y124_L0.9991.00
221_L225_S0.9931.00
213_Q216_D0.9931.00
110_P150_I0.9851.00
107_A116_A0.9831.00
226_V229_V0.9831.00
112_A115_K0.9811.00
138_S153_R0.9801.00
50_G67_L0.9781.00
177_I218_I0.9741.00
81_I253_D0.9701.00
95_F104_S0.9581.00
32_N37_P0.9581.00
218_I246_Y0.9541.00
117_Y143_V0.9521.00
107_A110_P0.9521.00
26_I277_V0.9471.00
212_I263_A0.9471.00
183_G187_L0.9451.00
18_I28_Y0.9431.00
214_L240_E0.9391.00
188_G191_A0.9371.00
126_D166_I0.9341.00
222_A238_I0.9321.00
273_V277_V0.9301.00
233_F254_V0.9291.00
181_V236_I0.9241.00
145_E148_T0.9231.00
220_E223_V0.9221.00
86_D130_I0.9111.00
151_E155_M0.9071.00
209_P212_I0.9021.00
199_W204_A0.9011.00
107_A113_A0.8941.00
19_K22_N0.8921.00
129_P165_I0.8891.00
21_L26_I0.8891.00
130_I161_L0.8801.00
148_T151_E0.8761.00
179_C219_R0.8731.00
65_A79_D0.8721.00
25_Q273_V0.8681.00
217_N224_K0.8621.00
113_A146_G0.8621.00
152_H155_M0.8571.00
202_N205_L0.8511.00
189_C192_R0.8511.00
111_D115_K0.8361.00
20_A24_R0.8361.00
88_I165_I0.8321.00
113_A150_I0.8301.00
70_A73_H0.8271.00
21_L273_V0.8221.00
218_I238_I0.8181.00
170_I241_H0.8141.00
86_D163_V0.8131.00
56_S61_L0.8111.00
240_E244_K0.8101.00
236_I248_I0.8101.00
49_V52_I0.8081.00
144_Y147_K0.8081.00
15_K19_K0.8041.00
43_A47_Y0.8021.00
244_K247_V0.7981.00
126_D149_I0.7971.00
171_K241_H0.7921.00
34_G37_P0.7841.00
86_D89_L0.7781.00
80_A230_K0.7761.00
171_K243_S0.7751.00
114_M117_Y0.7731.00
191_A194_I0.7731.00
126_D140_I0.7721.00
49_V75_I0.7721.00
238_I246_Y0.7701.00
221_L238_I0.7691.00
207_G210_T0.7681.00
153_R164_H0.7671.00
198_E202_N0.7591.00
273_V276_I0.7571.00
17_I20_A0.7511.00
65_A68_E0.7471.00
226_V231_G0.7401.00
222_A236_I0.7381.00
88_I104_S0.7361.00
121_G168_E0.7341.00
62_Y65_A0.7271.00
16_L268_V0.7261.00
121_G124_L0.7231.00
64_S74_T0.7211.00
59_R62_Y0.7211.00
218_I221_L0.7201.00
177_I238_I0.7201.00
170_I174_E0.7201.00
130_I163_V0.7171.00
205_L208_N0.7161.00
18_I30_V0.7161.00
181_V223_V0.7121.00
186_L223_V0.7091.00
169_Y239_L0.7091.00
94_L251_L0.7031.00
153_R157_N0.7021.00
171_K174_E0.7011.00
193_N209_P0.6991.00
118_E147_K0.6971.00
120_M168_E0.6971.00
241_H244_K0.6961.00
201_A204_A0.6961.00
144_Y148_T0.6951.00
100_P217_N0.6931.00
73_H277_V0.6931.00
79_D89_L0.6931.00
199_W203_V0.6921.00
89_L93_K0.6911.00
233_F255_P0.6891.00
188_G219_R0.6841.00
219_R222_A0.6821.00
37_P40_F0.6811.00
22_N28_Y0.6801.00
171_K239_L0.6771.00
112_A116_A0.6741.00
99_I221_L0.6741.00
184_D227_K0.6741.00
102_P247_V0.6711.00
117_Y146_G0.6701.00
64_S68_E0.6691.00
22_N25_Q0.6671.00
30_V41_N0.6651.00
213_Q217_N0.6641.00
196_P201_A0.6631.00
193_N196_P0.6601.00
188_G193_N0.6591.00
149_I153_R0.6501.00
168_E245_G0.6461.00
18_I21_L0.6451.00
149_I152_H0.6451.00
99_I224_K0.6431.00
84_C253_D0.6431.00
61_L82_G0.6411.00
141_R169_Y0.6401.00
51_I272_L0.6391.00
192_R195_P0.6371.00
185_E227_K0.6341.00
274_D277_V0.6341.00
268_V272_L0.6311.00
93_K225_S0.6281.00
171_K175_R0.6271.00
16_L20_A0.6241.00
176_D237_D0.6211.00
126_D164_H0.6191.00
204_A207_G0.6181.00
140_I145_E0.6161.00
189_C193_N0.6131.00
93_K229_V0.6121.00
190_Y193_N0.6121.00
91_Y104_S0.6111.00
225_S248_I0.6101.00
78_T82_G0.6091.00
140_I146_G0.6081.00
262_L265_G0.6041.00
146_G150_I0.6041.00
80_A231_G0.6041.00
50_G53_R0.6021.00
16_L19_K0.6011.00
63_S67_L0.6001.00
201_A205_L0.5971.00
59_R64_S0.5961.00
91_Y165_I0.5961.00
187_L191_A0.5921.00
179_C238_I0.5911.00
105_I120_M0.5871.00
207_G263_A0.5861.00
153_R156_L0.5831.00
117_Y123_P0.5821.00
33_V37_P0.5811.00
231_G234_V0.5801.00
77_S230_K0.5781.00
35_Q38_I0.5751.00
199_W205_L0.5751.00
92_S106_I0.5711.00
97_H225_S0.5691.00
60_A63_S0.5681.00
180_I233_F0.5661.00
198_E201_A0.5651.00
31_I38_I0.5641.00
150_I164_H0.5621.00
203_V206_G0.5591.00
64_S67_L0.5581.00
116_A166_I0.5581.00
74_T78_T0.5571.00
269_A273_V0.5571.00
217_N246_Y0.5551.00
67_L70_A0.5551.00
207_G211_P0.5541.00
255_P268_V0.5511.00
17_I21_L0.5501.00
208_N212_I0.5481.00
269_A272_L0.5471.00
94_L97_H0.5471.00
101_I104_S0.5461.00
102_P168_E0.5431.00
123_P169_Y0.5411.00
102_P249_N0.5371.00
25_Q270_E0.5371.00
79_D230_K0.5361.00
235_S256_E0.5351.00
194_I199_W0.5351.00
145_E149_I0.5351.00
91_Y95_F0.5341.00
60_A64_S0.5341.00
222_A226_V0.5331.00
268_V271_K0.5331.00
138_S148_T0.5321.00
58_Y63_S0.5301.00
80_A84_C0.5301.00
226_V236_I0.5291.00
106_I129_P0.5271.00
94_L101_I0.5271.00
99_I225_S0.5271.00
272_L276_I0.5251.00
22_N30_V0.5231.00
202_N208_N0.5221.00
59_R63_S0.5211.00
174_E243_S0.5201.00
266_I274_D0.5171.00
16_L259_G0.5161.00
204_A210_T0.5151.00
110_P113_A0.5151.00
105_I112_A0.5141.00
222_A225_S0.5141.00
55_V59_R0.5141.00
122_F141_R0.5121.00
180_I235_S0.5121.00
221_L248_I0.5111.00
155_M160_A0.5101.00
60_A67_L0.5091.00
62_Y82_G0.5071.00
198_E205_L0.5071.00
84_C90_T0.5031.00
15_K40_F0.5011.00
200_R205_L0.5001.00
224_K229_V0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3vpbA 3 1 100 0.221 Contact Map
3vpdA 3 0.9858 100 0.242 Contact Map
4iwxA 3 0.9823 100 0.263 Contact Map
1a9xA 3 0.9858 100 0.283 Contact Map
3r5xA 2 0.9716 100 0.289 Contact Map
3e5nA 2 0.9326 100 0.294 Contact Map
4eg0A 2 0.9184 100 0.297 Contact Map
3i12A 2 0.9716 100 0.299 Contact Map
4fu0A 2 0.9645 100 0.299 Contact Map
2qf7A 4 0.8369 100 0.304 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0102 seconds.