GREMLIN Database
Q7LXQ7 - Uncharacterized protein
UniProt: Q7LXQ7 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 178 (153)
Sequences: 1100 (653)
Seq/√Len: 52.8

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
124_S149_H4.8891.00
55_L119_R3.2241.00
123_Y130_K3.0041.00
133_W149_H2.9951.00
133_W157_C2.7511.00
34_F37_Y2.5201.00
124_S133_W2.4991.00
50_K53_K2.4691.00
167_L171_L2.4411.00
121_R155_D2.3501.00
127_G145_E2.3061.00
107_H147_H2.3051.00
60_R63_E2.2451.00
23_Q60_R2.1911.00
125_V128_K2.1221.00
121_R134_K2.0491.00
45_K48_L2.0221.00
22_K25_E2.0021.00
28_D31_V1.9291.00
25_E28_D1.7560.99
100_P151_N1.7280.99
87_L93_A1.7170.99
28_D32_V1.6860.99
123_Y150_V1.6680.99
27_D31_V1.6550.98
109_H147_H1.6540.98
61_I64_S1.6200.98
126_I131_I1.5360.97
27_D32_V1.5230.97
33_T36_E1.5150.97
53_K56_P1.4740.97
115_Y141_V1.4680.97
54_V95_F1.4380.96
27_D30_K1.4300.96
55_L59_E1.4160.96
62_A67_I1.3570.95
125_V148_Y1.3360.94
74_I94_G1.3330.94
133_W139_F1.3330.94
113_S161_D1.3280.94
151_N155_D1.2680.93
25_E29_L1.2480.92
25_E30_K1.2470.92
51_F158_I1.2440.92
127_G146_I1.2350.92
119_R155_D1.2330.92
109_H113_S1.2270.91
58_L97_L1.2190.91
103_A150_V1.2140.91
151_N156_D1.2140.91
123_Y132_E1.2100.91
106_P146_I1.2050.91
33_T37_Y1.2020.91
113_S163_T1.1930.90
115_Y161_D1.1800.90
73_K96_Q1.1470.88
108_S144_N1.1300.88
33_T38_T1.1200.87
130_K150_V1.1050.86
168_L173_I1.0970.86
122_G133_W1.0940.86
109_H149_H1.0770.85
79_P137_D1.0730.85
118_F158_I1.0600.84
130_K149_H1.0560.84
111_M174_L1.0520.84
101_G122_G1.0480.83
94_G161_D1.0450.83
37_Y174_L1.0310.82
59_E63_E1.0280.82
97_L158_I1.0260.82
132_E152_T1.0250.82
74_I117_V1.0140.81
105_K123_Y1.0080.81
107_H113_S1.0030.80
116_L138_V0.9990.80
115_Y159_L0.9960.80
119_R124_S0.9950.80
107_H149_H0.9790.79
141_V147_H0.9780.79
146_I149_H0.9770.79
98_I132_E0.9770.79
29_L32_V0.9760.79
98_I151_N0.9750.79
149_H157_C0.9600.77
88_T93_A0.9580.77
73_K94_G0.9510.77
110_N144_N0.9510.77
54_V58_L0.9430.76
59_E62_A0.9420.76
96_Q115_Y0.9390.76
106_P148_Y0.9370.76
23_Q26_Q0.9360.76
95_F158_I0.9230.75
23_Q28_D0.9210.74
51_F55_L0.9170.74
89_P122_G0.9110.74
51_F119_R0.9090.73
107_H115_Y0.8940.72
26_Q30_K0.8750.71
35_M166_G0.8730.70
55_L158_I0.8680.70
139_F157_C0.8640.70
24_I28_D0.8610.69
119_R135_A0.8600.69
58_L158_I0.8580.69
28_D117_V0.8550.69
99_K102_I0.8540.69
36_E111_M0.8520.69
92_M166_G0.8490.68
72_A102_I0.8380.67
96_Q161_D0.8360.67
125_V130_K0.8350.67
43_K60_R0.8290.66
125_V150_V0.8270.66
98_I114_I0.8260.66
113_S147_H0.8230.66
35_M80_S0.8170.65
67_I72_A0.8070.64
50_K154_D0.8040.64
96_Q159_L0.7990.64
91_M162_V0.7890.63
111_M165_S0.7870.62
103_A155_D0.7860.62
49_I159_L0.7810.62
45_K80_S0.7800.62
103_A148_Y0.7680.60
62_A97_L0.7670.60
76_F85_R0.7640.60
120_G137_D0.7630.60
30_K76_F0.7590.60
113_S146_I0.7590.60
123_Y152_T0.7530.59
86_G169_E0.7520.59
99_K156_D0.7490.59
93_A162_V0.7450.58
51_F95_F0.7440.58
96_Q149_H0.7440.58
51_F54_V0.7430.58
59_E156_D0.7410.58
144_N175_E0.7390.58
124_S139_F0.7330.57
81_T85_R0.7280.56
31_V34_F0.7280.56
167_L172_G0.7240.56
131_I145_E0.7240.56
121_R154_D0.7180.55
66_K69_N0.7140.55
26_Q29_L0.7100.55
110_N168_L0.7080.54
115_Y140_V0.7040.54
109_H124_S0.6970.53
82_C160_F0.6920.53
121_R152_T0.6840.52
112_A120_G0.6790.51
89_P172_G0.6770.51
73_K161_D0.6700.50
115_Y139_F0.6700.50
22_K27_D0.6680.50
98_I155_D0.6650.50
98_I153_G0.6640.50
115_Y147_H0.6630.50
24_I27_D0.6590.49
40_P46_P0.6540.49
87_L143_A0.6530.49
22_K39_N0.6520.48
124_S157_C0.6480.48
64_S126_I0.6470.48
128_K147_H0.6430.47
57_L60_R0.6340.47
87_L110_N0.6310.46
35_M38_T0.6300.46
25_E82_C0.6220.45
70_G75_M0.6190.45
130_K152_T0.6120.44
30_K34_F0.6100.44
23_Q27_D0.6100.44
90_T160_F0.6070.44
22_K26_Q0.6070.44
133_W147_H0.6050.44
129_E132_E0.6050.44
70_G161_D0.6030.43
57_L171_L0.6030.43
126_I145_E0.5930.42
76_F160_F0.5900.42
121_R135_A0.5900.42
117_V139_F0.5890.42
111_M143_A0.5860.42
38_T41_P0.5840.41
78_S116_L0.5820.41
94_G102_I0.5820.41
22_K30_K0.5810.41
115_Y126_I0.5810.41
97_L156_D0.5750.40
40_P91_M0.5750.40
58_L162_V0.5730.40
66_K80_S0.5710.40
56_P60_R0.5690.40
116_L136_G0.5690.40
104_T163_T0.5680.40
82_C90_T0.5680.40
57_L86_G0.5680.40
109_H163_T0.5580.39
24_I30_K0.5560.39
87_L111_M0.5530.38
115_Y163_T0.5510.38
58_L159_L0.5500.38
107_H163_T0.5500.38
93_A164_D0.5480.38
112_A168_L0.5480.38
123_Y148_Y0.5440.37
87_L94_G0.5400.37
71_V86_G0.5400.37
49_I78_S0.5390.37
23_Q154_D0.5290.36
43_K52_E0.5270.36
137_D166_G0.5260.36
124_S147_H0.5260.36
112_A145_E0.5240.35
93_A144_N0.5200.35
61_I124_S0.5190.35
125_V152_T0.5180.35
104_T159_L0.5150.35
167_L170_S0.5080.34
63_E153_G0.5050.34
113_S141_V0.5030.33
122_G157_C0.5020.33
69_N98_I0.5020.33
58_L95_F0.5010.33
41_P52_E0.5000.33
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3nw4A 3 0.9888 100 0.498 Contact Map
2d40A 3 0.7135 99.9 0.518 Contact Map
3bu7A 3 0.9494 99.9 0.536 Contact Map
2vqaA 3 0.7528 99.4 0.727 Contact Map
1j58A 5 0.927 99.3 0.737 Contact Map
3jzvA 5 0.7303 99.3 0.744 Contact Map
3ibmA 2 0.7191 99.2 0.754 Contact Map
2d5fA 5 0.6798 98.9 0.777 Contact Map
1dgwA 3 0.7135 98.9 0.778 Contact Map
1uijA 3 0.736 98.9 0.778 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0073 seconds.