GREMLIN Database
Q7LXN5 - Molybdopterin-guanine dinucleotide biosynthesis protein B (MobB)
UniProt: Q7LXN5 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 169 (152)
Sequences: 1390 (1018)
Seq/√Len: 82.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
20_E52_R6.1551.00
35_V53_Y4.3431.00
11_K48_K3.7751.00
27_K59_D3.5591.00
146_S149_A3.4991.00
34_A88_V3.1941.00
29_D152_L3.0441.00
9_G13_T2.7791.00
69_E75_P2.5091.00
34_A86_L2.4661.00
25_E29_D2.3361.00
6_H101_I2.2871.00
25_E148_N2.2741.00
19_I53_Y2.2551.00
23_L35_V2.1341.00
51_Y55_N1.9941.00
4_I83_I1.9151.00
29_D155_Y1.8611.00
68_E74_M1.8101.00
31_L155_Y1.8051.00
93_V101_I1.7971.00
22_V150_L1.7811.00
71_V75_P1.7071.00
6_H93_V1.6811.00
25_E151_L1.6771.00
70_S74_M1.6101.00
25_E147_D1.6051.00
44_D47_G1.5190.99
78_S81_T1.5160.99
108_N144_V1.4950.99
69_E73_F1.4700.99
109_N130_K1.4580.99
44_D51_Y1.4400.99
142_V153_T1.4390.99
70_S75_P1.4190.99
50_T63_F1.4100.99
83_I91_I1.3900.99
18_V150_L1.3740.99
104_K125_K1.3690.99
25_E28_K1.3490.99
17_S147_D1.3390.99
22_V151_L1.3160.98
54_R74_M1.3090.98
105_Y117_S1.2950.98
96_F99_V1.2840.98
36_V91_I1.2770.98
13_T106_I1.2460.98
36_V79_S1.2360.98
19_I24_R1.2340.98
129_Q145_T1.2180.97
62_L82_L1.2050.97
66_G76_S1.2040.97
140_V153_T1.2030.97
97_S103_K1.1980.97
143_E146_S1.1730.97
60_L74_M1.1710.97
7_I22_V1.1430.96
60_L87_P1.0840.95
33_V90_V1.0640.94
35_V58_S1.0570.94
19_I23_L1.0570.94
39_S65_E1.0510.94
19_I92_L1.0470.94
10_K97_S1.0340.94
5_F104_K1.0230.93
148_N152_L1.0190.93
64_Q82_L1.0140.93
5_F92_L1.0000.92
5_F157_L0.9700.91
152_L156_N0.9500.90
20_E55_N0.9470.90
31_L90_V0.9450.90
12_D48_K0.9420.90
107_I115_A0.9410.90
105_Y118_K0.9380.90
39_S53_Y0.9370.90
137_L141_K0.9340.90
25_E152_L0.9230.89
7_I104_K0.9180.89
26_I155_Y0.9140.89
20_E56_S0.8980.88
127_E144_V0.8980.88
43_L72_L0.8870.87
115_A126_K0.8830.87
132_N141_K0.8800.87
9_G61_I0.8790.87
105_Y123_D0.8770.86
125_K128_C0.8760.86
21_S147_D0.8560.85
34_A53_Y0.8480.84
142_V150_L0.8430.84
4_I101_I0.8380.84
5_F154_L0.8320.83
9_G106_I0.8310.83
69_E72_L0.8300.83
4_I91_I0.8270.83
47_G51_Y0.8260.83
39_S66_G0.8220.83
147_D150_L0.8210.83
26_I92_L0.8140.82
9_G95_G0.8120.82
70_S73_F0.8090.82
143_E149_A0.8060.81
22_V26_I0.8060.81
9_G53_Y0.7920.80
40_H64_Q0.7900.80
72_L75_P0.7810.79
136_I156_N0.7720.79
128_C131_T0.7690.78
38_H65_E0.7670.78
82_L96_F0.7630.78
42_K68_E0.7600.77
40_H50_T0.7600.77
79_S99_V0.7600.77
60_L85_L0.7590.77
142_V147_D0.7540.77
138_D141_K0.7460.76
10_K103_K0.7400.76
9_G14_G0.7360.75
18_V104_K0.7320.75
124_I157_L0.7300.75
26_I151_L0.7260.74
84_T158_M0.7230.74
107_I130_K0.7230.74
81_T84_T0.7220.74
9_G15_K0.7190.73
149_A152_L0.7190.73
154_L158_M0.7180.73
46_A55_N0.7180.73
53_Y56_S0.7160.73
43_L70_S0.7080.72
50_T53_Y0.7070.72
98_N120_V0.7050.72
128_C132_N0.7040.72
104_K127_E0.7020.72
65_E68_E0.6930.71
31_L89_D0.6910.70
137_L140_V0.6900.70
42_K66_G0.6840.70
23_L53_Y0.6830.70
44_D48_K0.6820.69
38_H95_G0.6800.69
6_H123_D0.6750.69
44_D70_S0.6750.69
71_V74_M0.6710.68
40_H43_L0.6710.68
38_H103_K0.6700.68
22_V147_D0.6640.67
10_K115_A0.6620.67
24_R27_K0.6620.67
39_S63_F0.6610.67
80_L99_V0.6590.67
136_I140_V0.6590.67
39_S73_F0.6560.66
38_H41_H0.6550.66
45_L51_Y0.6500.66
36_V82_L0.6400.65
32_K59_D0.6380.64
105_Y119_Q0.6360.64
39_S42_K0.6310.63
12_D19_I0.6310.63
142_V157_L0.6290.63
97_S102_G0.6280.63
38_H49_D0.6160.62
68_E73_F0.6130.61
17_S26_I0.6110.61
79_S116_I0.6070.60
11_K19_I0.6060.60
38_H97_S0.6050.60
3_C34_A0.6030.60
3_C91_I0.5960.59
63_F68_E0.5960.59
64_Q76_S0.5910.58
84_T156_N0.5900.58
49_D97_S0.5870.58
107_I112_E0.5870.58
18_V127_E0.5860.58
6_H40_H0.5840.58
147_D151_L0.5800.57
62_L71_V0.5800.57
86_L91_I0.5790.57
8_I105_Y0.5770.57
98_N116_I0.5760.57
60_L88_V0.5760.57
50_T61_I0.5760.57
68_E72_L0.5750.56
42_K98_N0.5680.55
55_N61_I0.5670.55
52_R55_N0.5670.55
11_K106_I0.5650.55
24_R35_V0.5640.55
105_Y111_N0.5640.55
34_A62_L0.5620.55
34_A60_L0.5560.54
6_H99_V0.5520.53
93_V96_F0.5500.53
62_L86_L0.5480.53
80_L100_D0.5460.53
84_T110_V0.5460.53
127_E142_V0.5460.53
25_E146_S0.5440.52
137_L148_N0.5420.52
3_C13_T0.5410.52
39_S97_S0.5400.52
3_C90_V0.5370.51
138_D156_N0.5360.51
52_R56_S0.5350.51
44_D91_I0.5320.51
43_L73_F0.5310.51
76_S109_N0.5300.50
78_S99_V0.5260.50
9_G16_T0.5230.50
39_S69_E0.5230.50
62_L77_V0.5220.49
35_V101_I0.5220.49
29_D151_L0.5180.49
47_G58_S0.5150.49
44_D63_F0.5150.49
5_F19_I0.5140.48
81_T85_L0.5130.48
64_Q93_V0.5120.48
41_H49_D0.5050.47
108_N129_Q0.5050.47
119_Q156_N0.5050.47
23_L61_I0.5040.47
17_S21_S0.5040.47
114_E117_S0.5020.47
30_N155_Y0.5000.47
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4nkrA 2 0.929 100 0.405 Contact Map
1xjcA 2 0.8343 100 0.443 Contact Map
1np6A 2 0.9467 99.8 0.643 Contact Map
2f1rA 2 0.8521 99.6 0.698 Contact Map
4ehxA 1 0.8047 99.3 0.756 Contact Map
2wsmA 2 0.8935 99 0.784 Contact Map
2hf9A 2 0.8994 98.7 0.802 Contact Map
3fgnA 2 0.8876 98.6 0.813 Contact Map
4a0gA 2 0.929 98.4 0.819 Contact Map
1s1mA 4 0.9704 98.3 0.829 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0068 seconds.