Q7LXL7 - SULSO - GREMLIN Contacts

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Q7LXL7 - Uncharacterized protein

UniProt:	Q7LXL7	Sequences: MLLHYLKTLSNYGEIITGSKNETKLVKEIRKILEDNSDEIRLIPIRVLNWEQKELIFECESKLIDAISLPYSLSTEIEADVVDNFKDCNGRNLIKVRIQNLYEINKLYIEAVENNCLGIIFSLDNEKRKFMIKYGDLLSHKPSYPPPIPAFYVKENDFPYIKGKCRISLKTDLNPFATGYIVEAIRNSRNENKIIHITAHHDHWFIGERDNLLAVALLRQFRSNIYETHLISFTAEESGSFNFSTFSWSHGSREFLKNYKNVDDILLNINMDNISEESLVLKTVPGLLELSRKYFKNVVESPEIYSDGYSYIKAGIPSITIESLGNIHYHGEYDIIETDKPNVFSNVTTILDTINKIINENIEYKTHEMRDQLKNNLWELPAELKSYLVNVKDILDKNYTEVYRKIVKLYGGILAFNQPYSKVELFHKIKGLNIARKNDVCIEDLGCIKRLRNDEIYNRFYLYYINELKELITTEYINQLYFILKKFF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	488 (438)
Sequences:	1243 (883)
Seq/√Len:	42.2

HALSA - Q9HNP7 Q9HRR8
SULSO - Q7LXL7

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
93_L	116_C	7.404	1.00
88_C	93_L	5.298	1.00
118_G	167_I	4.279	1.00
30_R	34_E	4.138	1.00
267_L	358_I	3.830	1.00
81_V	161_I	3.620	1.00
260_K	314_A	3.569	1.00
197_I	355_N	3.495	1.00
256_L	310_S	3.485	1.00
32_I	35_D	3.317	1.00
256_L	314_A	3.283	1.00
80_D	91_R	3.264	1.00
88_C	116_C	3.231	1.00
45_I	258_N	3.166	1.00
271_M	351_L	3.137	1.00
345_S	349_T	3.134	1.00
201_H	232_S	3.103	1.00
220_Q	223_S	3.079	1.00
198_T	268_N	3.061	1.00
76_E	166_R	2.815	1.00
190_N	225_I	2.769	1.00
236_E	329_Y	2.728	1.00
193_K	427_H	2.638	1.00
381_P	395_L	2.605	1.00
69_L	150_A	2.586	1.00
174_N	177_A	2.558	1.00
159_P	163_G	2.427	1.00
6_L	10_S	2.379	1.00
90_G	117_L	2.371	1.00
82_V	88_C	2.312	1.00
210_D	236_E	2.283	1.00
33_L	219_R	2.271	1.00
235_A	241_F	2.261	1.00
65_D	69_L	2.252	1.00
236_E	330_H	2.222	1.00
22_E	180_Y	2.173	1.00
66_A	69_L	2.128	0.99
445_L	454_D	2.111	0.99
210_D	330_H	2.110	0.99
192_N	423_V	2.096	0.99
337_E	341_P	2.025	0.99
273_N	276_E	2.022	0.99
103_E	236_E	2.018	0.99
200_H	210_D	2.007	0.99
96_V	119_I	2.006	0.99
64_I	68_S	1.994	0.99
254_E	257_K	1.978	0.99
65_D	68_S	1.955	0.99
81_V	94_I	1.937	0.99
44_P	178_T	1.937	0.99
222_R	230_L	1.890	0.99
19_S	51_E	1.886	0.99
210_D	329_Y	1.880	0.99
96_V	121_F	1.879	0.99
120_I	165_C	1.876	0.99
5_Y	28_E	1.825	0.98
58_E	166_R	1.807	0.98
78_E	166_R	1.804	0.98
237_E	329_Y	1.783	0.98
80_D	164_K	1.768	0.98
373_L	452_R	1.768	0.98
103_E	329_Y	1.763	0.98
109_I	113_E	1.745	0.98
199_A	211_N	1.742	0.98
153_V	158_F	1.723	0.97
29_I	215_V	1.722	0.97
196_H	229_H	1.716	0.97
22_E	234_T	1.709	0.97
30_R	40_I	1.699	0.97
197_I	351_L	1.675	0.97
23_T	180_Y	1.672	0.97
16_I	19_S	1.664	0.97
183_E	231_I	1.654	0.97
269_I	355_N	1.652	0.97
79_A	117_L	1.641	0.97
98_I	123_L	1.638	0.97
136_D	139_S	1.619	0.96
394_I	398_N	1.618	0.96
27_K	31_K	1.606	0.96
29_I	201_H	1.593	0.96
442_I	445_L	1.574	0.96
137_L	140_H	1.572	0.96
189_R	225_I	1.569	0.96
281_L	291_S	1.563	0.96
200_H	329_Y	1.560	0.95
205_F	332_E	1.544	0.95
194_I	229_H	1.526	0.95
50_W	150_A	1.502	0.94
409_L	413_I	1.493	0.94
64_I	69_L	1.489	0.94
185_I	229_H	1.486	0.94
160_Y	163_G	1.480	0.94
77_I	167_I	1.477	0.94
253_R	257_K	1.465	0.94
133_K	137_L	1.463	0.94
43_I	259_Y	1.458	0.93
112_V	147_P	1.445	0.93
26_V	42_L	1.442	0.93
228_T	359_N	1.433	0.93
200_H	236_E	1.432	0.93
187_N	191_E	1.431	0.93
200_H	330_H	1.429	0.93
412_G	416_F	1.426	0.93
272_D	306_S	1.422	0.93
8_T	11_N	1.419	0.93
269_I	351_L	1.414	0.92
304_I	309_Y	1.411	0.92
81_V	165_C	1.407	0.92
195_I	358_I	1.406	0.92
20_K	24_K	1.391	0.92
198_T	233_F	1.386	0.92
99_Q	106_K	1.383	0.92
15_I	203_H	1.375	0.91
131_M	135_G	1.370	0.91
200_H	237_E	1.365	0.91
442_I	454_D	1.360	0.91
31_K	34_E	1.356	0.91
33_L	222_R	1.350	0.91
134_Y	137_L	1.331	0.90
79_A	88_C	1.331	0.90
306_S	329_Y	1.329	0.90
47_V	179_G	1.327	0.90
37_S	40_I	1.323	0.90
286_G	366_T	1.323	0.90
150_A	169_L	1.322	0.90
133_K	136_D	1.319	0.89
92_N	118_G	1.316	0.89
78_E	164_K	1.316	0.89
136_D	140_H	1.314	0.89
27_K	30_R	1.302	0.89
199_A	215_V	1.296	0.89
441_C	445_L	1.295	0.89
76_E	168_S	1.293	0.89
43_I	258_N	1.287	0.88
37_S	184_A	1.287	0.88
23_T	27_K	1.282	0.88
305_Y	329_Y	1.279	0.88
233_F	311_Y	1.269	0.88
290_L	294_Y	1.265	0.87
50_W	69_L	1.263	0.87
423_V	427_H	1.262	0.87
292_R	295_F	1.262	0.87
26_V	182_V	1.259	0.87
31_K	35_D	1.256	0.87
56_I	168_S	1.255	0.87
64_I	67_I	1.235	0.86
25_L	201_H	1.232	0.86
110_E	114_N	1.230	0.86
50_W	70_P	1.227	0.86
289_E	368_E	1.224	0.86
10_S	336_I	1.219	0.85
287_L	317_P	1.218	0.85
120_I	153_V	1.217	0.85
279_L	321_I	1.215	0.85
194_I	227_E	1.215	0.85
374_K	403_Y	1.215	0.85
390_N	393_D	1.212	0.85
441_C	449_K	1.211	0.85
236_E	306_S	1.211	0.85
103_E	306_S	1.204	0.85
384_L	391_V	1.185	0.84
281_L	350_I	1.182	0.84
290_L	357_I	1.180	0.83
9_L	219_R	1.154	0.82
336_I	340_K	1.142	0.81
402_V	406_I	1.142	0.81
294_Y	354_I	1.139	0.81
240_S	329_Y	1.134	0.81
179_G	235_A	1.132	0.81
57_F	151_F	1.132	0.81
441_C	447_C	1.130	0.81
103_E	237_E	1.128	0.81
72_S	75_T	1.121	0.80
93_L	119_I	1.120	0.80
94_I	150_A	1.119	0.80
103_E	305_Y	1.116	0.80
184_A	230_L	1.107	0.79
103_E	121_F	1.103	0.79
76_E	79_A	1.102	0.79
78_E	235_A	1.101	0.79
357_I	361_N	1.095	0.78
207_G	334_D	1.093	0.78
98_I	305_Y	1.086	0.78
418_Q	421_S	1.084	0.78
445_L	455_E	1.084	0.78
15_I	212_L	1.078	0.77
145_P	151_F	1.075	0.77
238_S	322_E	1.069	0.77
410_Y	414_L	1.069	0.77
63_L	68_S	1.064	0.76
208_E	334_D	1.059	0.76
179_G	234_T	1.051	0.76
221_F	352_D	1.047	0.75
190_N	193_K	1.045	0.75
116_C	317_P	1.033	0.74
282_K	300_E	1.032	0.74
456_I	459_R	1.026	0.74
213_L	344_F	1.020	0.73
411_G	414_L	1.019	0.73
152_Y	234_T	1.016	0.73
302_P	306_S	1.016	0.73
108_Y	119_I	1.012	0.73
240_S	308_G	1.011	0.73
233_F	268_N	1.009	0.73
193_K	264_D	0.999	0.72
221_F	241_F	0.999	0.72
352_D	356_K	0.997	0.72
268_N	318_S	0.990	0.71
131_M	136_D	0.989	0.71
195_I	266_L	0.988	0.71
89_N	117_L	0.986	0.71
206_I	331_G	0.980	0.70
103_E	210_D	0.979	0.70
98_I	103_E	0.975	0.70
381_P	396_D	0.968	0.69
406_I	413_I	0.965	0.69
409_L	425_L	0.962	0.69
94_I	120_I	0.961	0.69
420_Y	427_H	0.959	0.69
294_Y	353_T	0.950	0.68
192_N	449_K	0.950	0.68
87_D	91_R	0.949	0.68
45_I	254_E	0.943	0.67
392_K	396_D	0.943	0.67
118_G	166_R	0.937	0.67
38_D	187_N	0.935	0.67
303_E	307_D	0.929	0.66
255_F	265_I	0.929	0.66
302_P	308_G	0.928	0.66
188_S	224_N	0.925	0.66
317_P	409_L	0.925	0.66
22_E	201_H	0.922	0.66
290_L	354_I	0.922	0.66
97_R	101_L	0.921	0.65
26_V	180_Y	0.920	0.65
53_K	170_K	0.919	0.65
212_L	376_N	0.918	0.65
10_S	212_L	0.911	0.65
46_R	178_T	0.908	0.64
444_D	455_E	0.907	0.64
317_P	366_T	0.904	0.64
110_E	113_E	0.904	0.64
236_E	240_S	0.901	0.64
204_W	330_H	0.901	0.64
419_P	423_V	0.898	0.63
398_N	406_I	0.896	0.63
295_F	350_I	0.893	0.63
94_I	161_I	0.891	0.63
54_E	170_K	0.891	0.63
202_D	334_D	0.890	0.63
414_L	417_N	0.884	0.62
94_I	216_A	0.883	0.62
200_H	270_N	0.882	0.62
433_N	447_C	0.881	0.62
210_D	270_N	0.880	0.62
91_R	428_K	0.879	0.62
356_K	360_E	0.879	0.62
372_Q	375_N	0.877	0.62
400_T	404_R	0.876	0.62
409_L	412_G	0.876	0.62
288_L	368_E	0.875	0.61
183_E	255_F	0.875	0.61
299_V	302_P	0.875	0.61
203_H	212_L	0.872	0.61
413_I	437_K	0.867	0.61
290_L	358_I	0.860	0.60
236_E	305_Y	0.856	0.60
73_L	150_A	0.853	0.59
269_I	319_I	0.851	0.59
50_W	173_L	0.851	0.59
215_V	257_K	0.850	0.59
38_D	230_L	0.849	0.59
153_V	443_E	0.849	0.59
315_G	318_S	0.849	0.59
200_H	272_D	0.849	0.59
420_Y	423_V	0.844	0.59
28_E	32_I	0.844	0.59
55_L	151_F	0.843	0.59
9_L	29_I	0.840	0.58
237_E	240_S	0.836	0.58
382_A	396_D	0.836	0.58
216_A	422_K	0.835	0.58
290_L	295_F	0.835	0.58
291_S	412_G	0.832	0.58
93_L	153_V	0.832	0.58
432_L	435_A	0.831	0.57
209_R	339_D	0.831	0.57
43_I	284_V	0.830	0.57
41_R	259_Y	0.828	0.57
221_F	348_T	0.827	0.57
413_I	417_N	0.827	0.57
131_M	139_S	0.824	0.57
76_E	118_G	0.824	0.57
285_P	369_M	0.821	0.57
17_T	241_F	0.819	0.56
194_I	264_D	0.813	0.56
201_H	274_I	0.812	0.56
420_Y	424_E	0.811	0.56
402_V	453_N	0.808	0.55
374_K	395_L	0.806	0.55
60_E	381_P	0.803	0.55
7_K	336_I	0.801	0.55
218_L	300_E	0.798	0.54
237_E	330_H	0.797	0.54
302_P	305_Y	0.796	0.54
7_K	10_S	0.795	0.54
33_L	167_I	0.791	0.54
169_L	331_G	0.790	0.54
204_W	270_N	0.788	0.53
36_N	39_E	0.785	0.53
215_V	232_S	0.785	0.53
33_L	232_S	0.783	0.53
262_V	434_I	0.780	0.53
279_L	350_I	0.779	0.53
79_A	92_N	0.779	0.53
433_N	450_R	0.777	0.52
6_L	212_L	0.773	0.52
196_H	231_I	0.773	0.52
367_H	382_A	0.772	0.52
70_P	228_T	0.772	0.52
203_H	260_K	0.771	0.52
262_V	314_A	0.771	0.52
17_T	179_G	0.770	0.52
119_I	348_T	0.766	0.51
441_C	455_E	0.765	0.51
370_R	394_I	0.764	0.51
291_S	421_S	0.762	0.51
401_E	405_K	0.762	0.51
269_I	273_N	0.759	0.51
389_V	437_K	0.756	0.50
80_D	392_K	0.753	0.50
396_D	401_E	0.753	0.50
386_S	404_R	0.752	0.50
200_H	307_D	0.748	0.50
355_N	365_K	0.748	0.50
118_G	168_S	0.748	0.50
358_I	369_M	0.748	0.50
310_S	313_K	0.745	0.49
131_M	138_L	0.745	0.49
24_K	31_K	0.744	0.49
86_K	91_R	0.742	0.49
103_E	330_H	0.742	0.49
307_D	329_Y	0.741	0.49
96_V	358_I	0.738	0.49
37_S	274_I	0.737	0.49
186_R	192_N	0.734	0.48
217_L	273_N	0.734	0.48
319_I	354_I	0.732	0.48
8_T	28_E	0.728	0.48
202_D	234_T	0.725	0.48
203_H	237_E	0.723	0.47
58_E	76_E	0.722	0.47
331_G	335_I	0.722	0.47
367_H	410_Y	0.722	0.47
33_L	184_A	0.721	0.47
224_N	228_T	0.721	0.47
404_R	411_G	0.720	0.47
25_L	28_E	0.720	0.47
252_S	307_D	0.718	0.47
7_K	11_N	0.717	0.47
413_I	425_L	0.715	0.47
29_I	35_D	0.715	0.47
122_S	125_N	0.715	0.47
192_N	264_D	0.715	0.47
377_L	398_N	0.715	0.47
85_F	186_R	0.710	0.46
290_L	352_D	0.709	0.46
134_Y	139_S	0.707	0.46
398_N	410_Y	0.703	0.45
15_I	211_N	0.703	0.45
135_G	140_H	0.701	0.45
391_V	415_A	0.695	0.45
34_E	367_H	0.695	0.45
28_E	219_R	0.694	0.45
442_I	447_C	0.694	0.45
141_K	316_I	0.693	0.45
381_P	415_A	0.692	0.44
193_K	430_K	0.691	0.44
308_G	320_T	0.691	0.44
185_I	194_I	0.690	0.44
413_I	416_F	0.690	0.44
30_R	42_L	0.689	0.44
71_Y	97_R	0.687	0.44
19_S	22_E	0.685	0.44
203_H	211_N	0.685	0.44
236_E	270_N	0.684	0.44
61_S	65_D	0.683	0.44
46_R	176_F	0.683	0.44
103_E	240_S	0.683	0.44
182_V	281_L	0.682	0.44
344_F	452_R	0.682	0.44
434_I	437_K	0.680	0.43
261_N	265_I	0.679	0.43
191_E	227_E	0.678	0.43
210_D	306_S	0.677	0.43
62_K	66_A	0.674	0.43
308_G	445_L	0.674	0.43
125_N	155_E	0.674	0.43
424_E	428_K	0.673	0.43
183_E	258_N	0.672	0.43
304_I	308_G	0.671	0.42
96_V	101_L	0.670	0.42
86_K	196_H	0.668	0.42
200_H	252_S	0.668	0.42
441_C	446_G	0.666	0.42
410_Y	413_I	0.666	0.42
424_E	431_G	0.665	0.42
5_Y	219_R	0.665	0.42
135_G	139_S	0.665	0.42
266_L	364_Y	0.664	0.42
51_E	238_S	0.663	0.42
309_Y	448_I	0.662	0.42
79_A	165_C	0.661	0.42
406_I	410_Y	0.659	0.41
319_I	350_I	0.659	0.41
76_E	196_H	0.658	0.41
17_T	26_V	0.658	0.41
210_D	305_Y	0.657	0.41
125_N	158_F	0.656	0.41
132_I	136_D	0.655	0.41
218_L	360_E	0.655	0.41
6_L	161_I	0.654	0.41
88_C	368_E	0.654	0.41
112_V	212_L	0.652	0.41
120_I	382_A	0.652	0.41
374_K	407_V	0.650	0.41
54_E	168_S	0.650	0.41
431_G	435_A	0.650	0.41
292_R	296_K	0.649	0.40
448_I	453_N	0.648	0.40
21_N	25_L	0.648	0.40
378_W	395_L	0.647	0.40
98_I	329_Y	0.646	0.40
202_D	272_D	0.645	0.40
304_I	456_I	0.644	0.40
22_E	46_R	0.643	0.40
188_S	226_Y	0.642	0.40
37_S	161_I	0.641	0.40
449_K	452_R	0.640	0.40
270_N	330_H	0.639	0.40
407_V	411_G	0.639	0.40
86_K	119_I	0.638	0.39
82_V	335_I	0.638	0.39
370_R	374_K	0.636	0.39
77_I	119_I	0.635	0.39
10_S	269_I	0.634	0.39
62_K	69_L	0.634	0.39
382_A	407_V	0.633	0.39
150_A	331_G	0.633	0.39
42_L	180_Y	0.633	0.39
123_L	128_R	0.630	0.39
304_I	454_D	0.630	0.39
73_L	118_G	0.629	0.39
57_F	154_K	0.628	0.39
252_S	256_L	0.627	0.39
269_I	278_S	0.626	0.38
43_I	46_R	0.626	0.38
101_L	110_E	0.626	0.38
273_N	325_G	0.625	0.38
153_V	386_S	0.624	0.38
41_R	120_I	0.623	0.38
9_L	215_V	0.622	0.38
120_I	201_H	0.621	0.38
386_S	392_K	0.621	0.38
227_E	255_F	0.621	0.38
293_K	390_N	0.621	0.38
106_K	240_S	0.621	0.38
288_L	292_R	0.619	0.38
398_N	408_K	0.619	0.38
195_I	357_I	0.619	0.38
342_N	345_S	0.618	0.38
444_D	457_Y	0.618	0.38
161_I	402_V	0.618	0.38
217_L	361_N	0.617	0.38
33_L	269_I	0.617	0.38
323_S	347_V	0.616	0.38
134_Y	140_H	0.616	0.38
292_R	368_E	0.616	0.38
414_L	419_P	0.614	0.37
199_A	218_L	0.614	0.37
204_W	210_D	0.612	0.37
93_L	289_E	0.611	0.37
351_L	355_N	0.611	0.37
19_S	321_I	0.611	0.37
5_Y	9_L	0.610	0.37
98_I	104_I	0.610	0.37
339_D	344_F	0.609	0.37
87_D	117_L	0.608	0.37
254_E	258_N	0.608	0.37
39_E	187_N	0.606	0.37
291_S	425_L	0.606	0.37
396_D	414_L	0.605	0.37
103_E	303_E	0.605	0.37
214_A	310_S	0.604	0.36
87_D	94_I	0.602	0.36
411_G	415_A	0.602	0.36
97_R	449_K	0.601	0.36
408_K	415_A	0.600	0.36
27_K	161_I	0.600	0.36
106_K	124_D	0.600	0.36
19_S	429_I	0.599	0.36
382_A	415_A	0.595	0.36
382_A	389_V	0.594	0.36
236_E	272_D	0.594	0.36
307_D	315_G	0.592	0.35
103_E	204_W	0.592	0.35
235_A	438_N	0.591	0.35
60_E	223_S	0.591	0.35
236_E	308_G	0.591	0.35
209_R	275_S	0.589	0.35
289_E	421_S	0.589	0.35
157_D	160_Y	0.588	0.35
283_T	324_L	0.588	0.35
210_D	237_E	0.587	0.35
32_I	86_K	0.586	0.35
17_T	238_S	0.586	0.35
84_N	196_H	0.586	0.35
297_N	353_T	0.586	0.35
193_K	423_V	0.584	0.35
129_K	133_K	0.584	0.35
198_T	201_H	0.584	0.35
60_E	86_K	0.583	0.35
375_N	378_W	0.582	0.35
153_V	229_H	0.582	0.35
229_H	255_F	0.581	0.34
285_P	291_S	0.580	0.34
153_V	454_D	0.580	0.34
146_P	285_P	0.579	0.34
92_N	167_I	0.578	0.34
270_N	307_D	0.578	0.34
294_Y	357_I	0.577	0.34
401_E	417_N	0.577	0.34
123_L	304_I	0.577	0.34
397_K	443_E	0.576	0.34
448_I	455_E	0.576	0.34
392_K	404_R	0.576	0.34
293_K	297_N	0.575	0.34
309_Y	442_I	0.573	0.34
283_T	421_S	0.573	0.34
37_S	230_L	0.573	0.34
448_I	456_I	0.572	0.34
266_L	269_I	0.572	0.34
86_K	316_I	0.571	0.34
7_K	136_D	0.571	0.34
398_N	402_V	0.570	0.34
10_S	338_T	0.570	0.34
200_H	204_W	0.569	0.33
53_K	94_I	0.568	0.33
314_A	437_K	0.567	0.33
341_P	396_D	0.565	0.33
79_A	318_S	0.565	0.33
403_Y	412_G	0.565	0.33
283_T	288_L	0.563	0.33
426_F	436_R	0.562	0.33
342_N	346_N	0.562	0.33
135_G	138_L	0.561	0.33
451_L	457_Y	0.561	0.33
382_A	400_T	0.560	0.33
99_Q	128_R	0.559	0.33
152_Y	162_K	0.559	0.33
62_K	65_D	0.558	0.33
27_K	42_L	0.558	0.33
98_I	445_L	0.557	0.32
422_K	426_F	0.557	0.32
204_W	237_E	0.556	0.32
396_D	400_T	0.553	0.32
90_G	283_T	0.552	0.32
184_A	451_L	0.552	0.32
302_P	307_D	0.552	0.32
110_E	123_L	0.552	0.32
412_G	421_S	0.551	0.32
11_N	382_A	0.551	0.32
15_I	18_G	0.550	0.32
159_P	391_V	0.549	0.32
396_D	403_Y	0.549	0.32
23_T	43_I	0.549	0.32
313_K	452_R	0.549	0.32
28_E	449_K	0.548	0.32
34_E	168_S	0.548	0.32
49_N	179_G	0.547	0.32
311_Y	315_G	0.546	0.32
27_K	180_Y	0.546	0.32
240_S	330_H	0.546	0.32
198_T	323_S	0.545	0.31
49_N	195_I	0.545	0.31
358_I	373_L	0.544	0.31
268_N	276_E	0.544	0.31
394_I	402_V	0.543	0.31
405_K	408_K	0.542	0.31
15_I	199_A	0.541	0.31
199_A	237_E	0.541	0.31
234_T	254_E	0.541	0.31
268_N	285_P	0.541	0.31
71_Y	173_L	0.541	0.31
50_W	238_S	0.539	0.31
161_I	319_I	0.539	0.31
24_K	231_I	0.538	0.31
82_V	354_I	0.538	0.31
117_L	265_I	0.537	0.31
358_I	366_T	0.537	0.31
239_G	416_F	0.536	0.31
75_T	257_K	0.536	0.31
233_F	252_S	0.536	0.31
164_K	354_I	0.535	0.31
77_I	118_G	0.535	0.31
210_D	240_S	0.534	0.31
91_R	116_C	0.533	0.31
98_I	304_I	0.532	0.30
103_E	200_H	0.531	0.30
61_S	64_I	0.527	0.30
375_N	414_L	0.527	0.30
15_I	215_V	0.526	0.30
67_I	449_K	0.526	0.30
391_V	402_V	0.526	0.30
403_Y	410_Y	0.526	0.30
151_F	334_D	0.525	0.30
194_I	230_L	0.525	0.30
133_K	138_L	0.523	0.30
335_I	435_A	0.523	0.30
31_K	57_F	0.522	0.30
81_V	118_G	0.522	0.30
404_R	407_V	0.522	0.30
49_N	52_Q	0.522	0.30
103_E	272_D	0.521	0.30
291_S	319_I	0.520	0.29
382_A	385_K	0.519	0.29
58_E	135_G	0.519	0.29
271_M	274_I	0.518	0.29
59_C	273_N	0.517	0.29
53_K	372_Q	0.517	0.29
76_E	170_K	0.516	0.29
306_S	330_H	0.515	0.29
403_Y	416_F	0.515	0.29
82_V	120_I	0.514	0.29
151_F	331_G	0.514	0.29
55_L	196_H	0.513	0.29
111_A	270_N	0.511	0.29
293_K	296_K	0.511	0.29
92_N	140_H	0.511	0.29
400_T	405_K	0.510	0.29
186_R	197_I	0.510	0.29
312_I	317_P	0.509	0.29
290_L	395_L	0.507	0.28
108_Y	269_I	0.507	0.28
57_F	165_C	0.507	0.28
30_R	218_L	0.506	0.28
442_I	455_E	0.505	0.28
96_V	407_V	0.505	0.28
386_S	401_E	0.504	0.28
42_L	203_H	0.504	0.28
98_I	102_Y	0.503	0.28
151_F	171_T	0.503	0.28
200_H	240_S	0.501	0.28
263_D	360_E	0.501	0.28
31_K	178_T	0.501	0.28
50_W	73_L	0.500	0.28
410_Y	416_F	0.500	0.28

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4tweA	2	0.9693	100	0.325	Contact Map
3fedA	2	0.9693	100	0.338	Contact Map
3kasA	2	0.9693	100	0.355	Contact Map
2ek8A	2	0.7254	100	0.544	Contact Map
3iibA	2	0.7316	100	0.557	Contact Map
4r12A	1	0.8422	100	0.682	Contact Map
3k9tA	3	0.75	100	0.721	Contact Map
4mhpA	1	0.4631	100	0.761	Contact Map
1tkjA	1	0.459	100	0.763	Contact Map
4f9uA	1	0.4816	100	0.767	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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