Q7LXF6 - SULSO - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q7LXF6 - Uncharacterized protein

UniProt:	Q7LXF6	Sequences: MANYASFIEVLISNFNRYPYTLFPLYAKAYKNPLIVALKSLLRHYPFVVELKNGEKVLVTGKGYKIASYYAFLYLARKKGKKINIIDIDENTIKIIYDTNEIILKDYTKGDIIGVYIKEEYQDVNVKDKTVIDCGAAIGDSAIYFSLKGAKRVIAIEAYPKIAKIAEENVKLNNFKNIQIVNAACGTDGIVTVNPRLGGGPTPLMSSNNGYTVPSFSLQGLIKNFQVEKGSVLKLDCEGCEYEFLLNADSSTLEYFDQIIMEYHYGYSHLKRKLEKAGFKVKVTKPELWNNQYKKGLILGKLYASRE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	307 (254)
Sequences:	242 (233)
Seq/√Len:	14.6

HALSA - Q9HQP5
SULSO - Q7LXF6 Q7LXE9 Q97XU3 Q97XG4 Q97XT4 Q7LXG2 Q7LXF9 Q97X54 Q7LXE1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
219_Q	247_N	5.742	1.00
237_C	244_F	4.403	1.00
156_I	221_L	3.731	1.00
184_A	215_S	3.504	0.99
219_Q	279_F	3.469	0.99
136_A	166_A	3.042	0.98
247_N	279_F	2.946	0.97
238_E	264_H	2.931	0.97
219_Q	249_D	2.673	0.95
262_E	268_S	2.636	0.95
136_A	155_A	2.596	0.94
190_I	212_T	2.345	0.91
141_S	264_H	2.328	0.90
137_A	262_E	2.268	0.89
134_C	185_C	2.246	0.89
186_G	191_V	2.166	0.87
233_L	253_L	2.122	0.86
233_L	247_N	2.098	0.85
235_L	244_F	2.073	0.84
235_L	262_E	2.065	0.84
137_A	140_D	1.992	0.82
233_L	259_I	1.989	0.82
160_P	211_Y	1.984	0.81
156_I	185_C	1.984	0.81
253_L	277_A	1.980	0.81
186_G	240_C	1.968	0.81
184_A	213_V	1.940	0.80
151_K	231_S	1.939	0.80
192_T	212_T	1.922	0.79
253_L	256_F	1.921	0.79
259_I	262_E	1.896	0.78
89_D	94_K	1.869	0.77
133_D	234_K	1.868	0.77
233_L	249_D	1.838	0.76
144_Y	279_F	1.825	0.75
158_A	193_V	1.822	0.75
91_N	94_K	1.818	0.75
129_K	258_Q	1.760	0.73
186_G	215_S	1.752	0.72
237_C	262_E	1.733	0.72
256_F	279_F	1.714	0.71
218_L	252_T	1.699	0.70
142_A	178_I	1.696	0.70
219_Q	233_L	1.680	0.69
131_V	153_V	1.651	0.68
128_D	151_K	1.646	0.67
143_I	169_N	1.609	0.66
181_V	221_L	1.604	0.65
134_C	262_E	1.602	0.65
163_A	167_E	1.599	0.65
134_C	244_F	1.599	0.65
193_V	240_C	1.579	0.64
33_P	37_A	1.563	0.63
262_E	271_K	1.555	0.63
137_A	253_L	1.505	0.60
253_L	263_Y	1.504	0.60
190_I	214_P	1.501	0.60
136_A	175_F	1.474	0.59
235_L	241_E	1.462	0.58
244_F	282_K	1.455	0.58
168_E	171_K	1.430	0.56
134_C	237_C	1.398	0.54
121_Y	184_A	1.396	0.54
129_K	231_S	1.386	0.54
232_V	237_C	1.384	0.54
232_V	235_L	1.378	0.53
135_G	139_G	1.343	0.51
141_S	145_F	1.339	0.51
134_C	235_L	1.327	0.51
236_D	239_G	1.325	0.50
233_L	279_F	1.320	0.50
168_E	185_C	1.313	0.50
135_G	157_E	1.302	0.49
131_V	145_F	1.301	0.49
250_S	254_E	1.294	0.49
140_D	263_Y	1.281	0.48
163_A	180_I	1.251	0.46
244_F	259_I	1.242	0.46
143_I	173_N	1.240	0.46
167_E	180_I	1.231	0.45
163_A	188_D	1.229	0.45
183_A	216_F	1.225	0.45
238_E	245_L	1.213	0.44
237_C	247_N	1.210	0.44
235_L	264_H	1.210	0.44
244_F	262_E	1.207	0.44
198_G	201_P	1.193	0.43
129_K	151_K	1.190	0.43
234_K	238_E	1.188	0.43
134_C	137_A	1.184	0.43
217_S	220_G	1.181	0.42
242_Y	273_K	1.169	0.42
171_K	218_L	1.140	0.40
53_N	57_V	1.140	0.40
132_I	185_C	1.136	0.40
259_I	274_L	1.129	0.40
137_A	268_S	1.129	0.40
233_L	262_E	1.127	0.40
35_I	38_L	1.124	0.39
111_D	114_G	1.104	0.38
159_Y	162_I	1.102	0.38
91_N	95_I	1.102	0.38
160_P	213_V	1.099	0.38
37_A	42_L	1.096	0.38
132_I	263_Y	1.083	0.37
262_E	281_V	1.082	0.37
94_K	279_F	1.080	0.37
170_V	193_V	1.073	0.37
144_Y	169_N	1.071	0.37
238_E	241_E	1.071	0.37
236_D	262_E	1.071	0.37
132_I	227_V	1.064	0.36
273_K	277_A	1.042	0.35
89_D	98_D	1.037	0.35
259_I	268_S	1.032	0.35
219_Q	253_L	1.029	0.35
48_V	278_G	1.028	0.34
128_D	164_K	1.024	0.34
241_E	245_L	1.024	0.34
60_T	165_I	1.020	0.34
163_A	182_N	1.016	0.34
271_K	275_E	1.013	0.34
129_K	284_T	1.013	0.34
141_S	253_L	1.011	0.34
169_N	173_N	1.010	0.34
244_F	265_Y	1.009	0.34
252_T	281_V	1.009	0.34
111_D	134_C	0.992	0.33
160_P	182_N	0.987	0.32
186_G	227_V	0.985	0.32
231_S	262_E	0.983	0.32
262_E	274_L	0.979	0.32
33_P	40_S	0.979	0.32
264_H	270_L	0.973	0.32
149_G	153_V	0.968	0.32
170_V	175_F	0.964	0.31
140_D	261_M	0.964	0.31
249_D	279_F	0.963	0.31
39_K	43_R	0.963	0.31
166_A	247_N	0.961	0.31
237_C	241_E	0.959	0.31
213_V	255_Y	0.949	0.31
188_D	217_S	0.943	0.30
202_T	209_N	0.942	0.30
216_F	245_L	0.942	0.30
268_S	271_K	0.937	0.30
242_Y	279_F	0.932	0.30
237_C	240_C	0.922	0.29
205_M	279_F	0.921	0.29
60_T	69_Y	0.913	0.29
177_N	184_A	0.912	0.29
170_V	206_S	0.912	0.29
89_D	95_I	0.908	0.29
131_V	231_S	0.907	0.29
154_I	182_N	0.901	0.28
167_E	171_K	0.900	0.28
133_D	241_E	0.888	0.28
175_F	178_I	0.886	0.28
184_A	218_L	0.881	0.28
131_V	149_G	0.879	0.27
185_C	221_L	0.878	0.27
135_G	239_G	0.877	0.27
261_M	268_S	0.876	0.27
257_D	280_K	0.874	0.27
205_M	209_N	0.865	0.27
150_A	237_C	0.864	0.27
134_C	266_G	0.863	0.27
236_D	264_H	0.854	0.26
188_D	220_G	0.849	0.26
122_Q	218_L	0.848	0.26
217_S	280_K	0.847	0.26
54_G	254_E	0.841	0.26
87_D	154_I	0.841	0.26
183_A	214_P	0.840	0.26
147_L	242_Y	0.840	0.26
235_L	268_S	0.839	0.26
152_R	179_Q	0.835	0.26
169_N	172_L	0.833	0.25
87_D	214_P	0.831	0.25
149_G	184_A	0.828	0.25
140_D	145_F	0.823	0.25
139_G	157_E	0.823	0.25
138_I	286_P	0.819	0.25
156_I	181_V	0.817	0.25
163_A	171_K	0.808	0.24
148_K	256_F	0.803	0.24
135_G	234_K	0.802	0.24
219_Q	237_C	0.798	0.24
133_D	157_E	0.794	0.24
232_V	260_I	0.792	0.24
133_D	139_G	0.791	0.24
34_L	41_L	0.790	0.24
133_D	238_E	0.789	0.24
263_Y	268_S	0.788	0.24
121_Y	264_H	0.788	0.24
237_C	249_D	0.788	0.24
147_L	166_A	0.786	0.24
46_P	177_N	0.786	0.24
164_K	167_E	0.778	0.23
264_H	271_K	0.769	0.23
257_D	274_L	0.766	0.23
132_I	221_L	0.765	0.23
146_S	153_V	0.762	0.23
40_S	44_H	0.762	0.23
264_H	268_S	0.759	0.22
175_F	196_R	0.758	0.22
258_Q	285_K	0.754	0.22
141_S	263_Y	0.753	0.22
253_L	262_E	0.753	0.22
94_K	253_L	0.751	0.22
40_S	55_E	0.746	0.22
253_L	258_Q	0.746	0.22
142_A	173_N	0.744	0.22
135_G	236_D	0.744	0.22
115_V	121_Y	0.741	0.22
64_Y	222_I	0.740	0.22
245_L	273_K	0.736	0.22
91_N	98_D	0.735	0.22
237_C	264_H	0.731	0.21
182_N	188_D	0.730	0.21
166_A	237_C	0.728	0.21
131_V	241_E	0.726	0.21
241_E	264_H	0.724	0.21
186_G	189_G	0.721	0.21
137_A	141_S	0.719	0.21
94_K	167_E	0.719	0.21
271_K	274_L	0.713	0.21
142_A	285_K	0.713	0.21
137_A	263_Y	0.713	0.21
134_C	192_T	0.708	0.21
33_P	38_L	0.707	0.21
157_E	163_A	0.706	0.20
184_A	262_E	0.706	0.20
56_K	100_N	0.705	0.20
158_A	184_A	0.705	0.20
145_F	264_H	0.700	0.20
35_I	40_S	0.694	0.20
72_F	95_I	0.693	0.20
185_C	217_S	0.693	0.20
207_S	251_S	0.690	0.20
159_Y	186_G	0.689	0.20
77_R	218_L	0.684	0.20
252_T	271_K	0.683	0.20
183_A	193_V	0.679	0.20
120_E	168_E	0.676	0.19
90_E	93_I	0.675	0.19
219_Q	245_L	0.675	0.19
177_N	242_Y	0.671	0.19
66_I	107_Y	0.670	0.19
140_D	235_L	0.667	0.19
150_A	153_V	0.666	0.19
32_N	42_L	0.665	0.19
146_S	241_E	0.662	0.19
195_P	211_Y	0.662	0.19
89_D	96_I	0.662	0.19
192_T	201_P	0.659	0.19
121_Y	238_E	0.658	0.19
155_A	165_I	0.658	0.19
263_Y	271_K	0.653	0.19
131_V	256_F	0.651	0.19
132_I	180_I	0.651	0.19
114_G	283_V	0.650	0.19
219_Q	256_F	0.649	0.19
55_E	87_D	0.649	0.19
50_E	254_E	0.648	0.18
138_I	186_G	0.646	0.18
43_R	47_F	0.644	0.18
33_P	36_V	0.643	0.18
40_S	43_R	0.639	0.18
97_Y	282_K	0.636	0.18
155_A	166_A	0.634	0.18
145_F	232_V	0.633	0.18
72_F	102_I	0.633	0.18
32_N	35_I	0.632	0.18
219_Q	257_D	0.632	0.18
143_I	276_K	0.631	0.18
39_K	101_E	0.631	0.18
112_I	145_F	0.628	0.18
247_N	282_K	0.624	0.18
76_A	251_S	0.623	0.18
231_S	257_D	0.622	0.18
137_A	144_Y	0.621	0.18
39_K	42_L	0.621	0.18
37_A	40_S	0.621	0.18
186_G	193_V	0.621	0.18
119_E	187_T	0.620	0.18
135_G	238_E	0.618	0.17
33_P	39_K	0.617	0.17
185_C	266_G	0.617	0.17
137_A	162_I	0.616	0.17
141_S	163_A	0.615	0.17
233_L	241_E	0.614	0.17
194_N	251_S	0.612	0.17
209_N	283_V	0.610	0.17
231_S	244_F	0.610	0.17
262_E	278_G	0.609	0.17
51_L	54_G	0.607	0.17
264_H	284_T	0.606	0.17
48_V	83_I	0.606	0.17
235_L	263_Y	0.605	0.17
80_G	216_F	0.601	0.17
85_I	121_Y	0.600	0.17
92_T	279_F	0.599	0.17
140_D	262_E	0.599	0.17
140_D	151_K	0.596	0.17
235_L	245_L	0.596	0.17
163_A	166_A	0.595	0.17
136_A	185_C	0.594	0.17
93_I	173_N	0.593	0.17
135_G	241_E	0.592	0.17
119_E	269_H	0.591	0.17
159_Y	193_V	0.589	0.17
177_N	229_K	0.589	0.17
190_I	254_E	0.589	0.17
35_I	42_L	0.588	0.17
247_N	273_K	0.583	0.16
201_P	218_L	0.582	0.16
36_V	51_L	0.582	0.16
50_E	65_K	0.578	0.16
188_D	221_L	0.576	0.16
175_F	210_G	0.575	0.16
233_L	256_F	0.573	0.16
161_K	217_S	0.570	0.16
166_A	230_G	0.570	0.16
218_L	233_L	0.569	0.16
70_Y	171_K	0.567	0.16
169_N	279_F	0.565	0.16
59_V	187_T	0.565	0.16
52_K	184_A	0.563	0.16
43_R	50_E	0.560	0.16
184_A	260_I	0.560	0.16
36_V	42_L	0.560	0.16
89_D	93_I	0.558	0.16
37_A	44_H	0.555	0.16
219_Q	282_K	0.555	0.16
32_N	43_R	0.553	0.16
90_E	105_K	0.551	0.15
142_A	151_K	0.551	0.15
253_L	268_S	0.547	0.15
186_G	223_K	0.546	0.15
128_D	131_V	0.545	0.15
103_I	216_F	0.544	0.15
146_S	178_I	0.544	0.15
230_G	249_D	0.544	0.15
249_D	252_T	0.542	0.15
238_E	263_Y	0.541	0.15
155_A	275_E	0.535	0.15
147_L	190_I	0.534	0.15
83_I	213_V	0.534	0.15
117_I	227_V	0.533	0.15
173_N	189_G	0.531	0.15
253_L	264_H	0.529	0.15
81_K	99_T	0.528	0.15
158_A	182_N	0.526	0.15
137_A	235_L	0.525	0.15
141_S	151_K	0.525	0.15
154_I	251_S	0.525	0.15
184_A	230_G	0.525	0.15
264_H	281_V	0.524	0.15
184_A	236_D	0.523	0.15
186_G	190_I	0.523	0.15
149_G	158_A	0.523	0.15
183_A	246_L	0.522	0.15
169_N	262_E	0.520	0.15
59_V	83_I	0.516	0.14
97_Y	131_V	0.515	0.14
71_A	79_K	0.510	0.14
66_I	92_T	0.510	0.14
140_D	264_H	0.509	0.14
188_D	216_F	0.508	0.14
152_R	261_M	0.508	0.14
232_V	279_F	0.507	0.14
247_N	256_F	0.506	0.14
169_N	174_N	0.505	0.14
93_I	128_D	0.505	0.14
268_S	279_F	0.503	0.14
204_L	270_L	0.503	0.14
34_L	38_L	0.503	0.14
52_K	169_N	0.501	0.14
120_E	260_I	0.500	0.14
58_L	163_A	0.500	0.14

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2py6A	4	0.8958	100	0.547	Contact Map
3opnA	1	0.5309	97.6	0.877	Contact Map
3kr9A	1	0.5244	97.1	0.887	Contact Map
3lecA	2	0.5342	96.9	0.89	Contact Map
3p2eA	1	0.57	96.8	0.89	Contact Map
3evzA	1	0.6156	96.8	0.891	Contact Map
3k6rA	1	0.7752	96.8	0.891	Contact Map
3eeyA	3	0.5603	96.7	0.892	Contact Map
3mtiA	2	0.5505	96.7	0.892	Contact Map
3gnlA	1	0.5309	96.7	0.892	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0091 seconds.