Q7LXE9 - SULSO - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

Q7LXE9 - Uncharacterized protein

UniProt:	Q7LXE9	Sequences: MGVFSKLRKSVGFTRLLLRYVDNWFDILYLTIANKKLAFLEVKLKDNNRIFLKNSIYDLYALLSLLKKGWKVKEADENNAILCKEVCLKIRTKKGADIGHIDEIYECKTYGESFKGVVIDVGASNADSSIFFATNGAEKVIALEPFPESYELGKYNIKINNLDNKVILLPYALTNYEGYVDFIISSDNPNVNTVSPSTQVMGLLGIKFDQKIKVPTTTLASLIQKYNIDRVYLLKMDCEGCEYAILRDLPAEVLNKIENIILEFHDYPQDLPDILRKAGFNVNYENKPIGILKAYKNDKLA	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	301 (236)
Sequences:	295 (286)
Seq/√Len:	18.6

HALSA - Q9HQP5 Q9HSW3
SULSO - Q7LXE9 Q97XT4 Q7LXF6 Q97XU3 Q97XG4 Q7LXG2 Q97X54 Q7LXF9 Q7LXE1

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
220_A	248_D	5.105	1.00
238_C	245_I	4.544	1.00
259_N	280_F	4.431	1.00
143_L	222_L	3.636	1.00
174_T	216_T	3.176	0.99
172_A	216_T	3.146	0.99
175_N	244_A	3.025	0.99
175_N	247_R	2.921	0.99
123_A	153_G	2.919	0.99
174_T	241_C	2.899	0.99
234_L	259_N	2.866	0.99
150_Y	168_L	2.819	0.98
150_Y	170_P	2.782	0.98
128_S	265_H	2.741	0.98
129_S	166_V	2.711	0.98
172_A	214_V	2.659	0.98
147_P	212_I	2.602	0.97
118_V	140_V	2.566	0.97
147_P	170_P	2.456	0.96
220_A	250_P	2.455	0.96
174_T	180_V	2.437	0.96
220_A	280_F	2.397	0.96
236_M	245_I	2.367	0.95
143_L	173_L	2.262	0.94
124_S	127_D	2.242	0.94
263_E	284_Y	2.216	0.93
121_V	173_L	2.182	0.93
179_Y	213_K	2.169	0.93
220_A	254_L	2.106	0.91
73_K	78_N	2.001	0.89
123_A	142_A	1.989	0.89
251_A	255_N	1.972	0.88
118_V	136_G	1.942	0.88
105_Y	110_Y	1.940	0.88
239_E	242_E	1.880	0.86
128_S	132_F	1.850	0.85
131_F	156_N	1.834	0.84
116_G	138_E	1.768	0.82
238_C	265_H	1.763	0.82
120_D	235_K	1.759	0.82
131_F	280_F	1.698	0.79
121_V	245_I	1.696	0.79
124_S	263_E	1.651	0.77
177_E	221_S	1.648	0.77
110_Y	132_F	1.637	0.77
254_L	259_N	1.606	0.75
217_T	221_S	1.590	0.75
150_Y	153_G	1.572	0.74
171_Y	217_T	1.552	0.73
239_E	265_H	1.551	0.73
133_A	140_V	1.537	0.72
238_C	241_C	1.535	0.72
181_D	213_K	1.531	0.72
177_E	217_T	1.518	0.71
116_G	136_G	1.514	0.71
263_E	269_Q	1.508	0.71
237_D	263_E	1.481	0.69
122_G	126_A	1.475	0.69
248_D	280_F	1.450	0.67
220_A	259_N	1.447	0.67
257_I	280_F	1.437	0.67
263_E	275_L	1.412	0.65
121_V	238_C	1.378	0.63
141_I	222_L	1.328	0.60
130_I	156_N	1.323	0.60
238_C	242_E	1.309	0.59
157_I	168_L	1.296	0.58
156_N	159_I	1.287	0.58
262_L	269_Q	1.278	0.57
248_D	259_N	1.255	0.56
236_M	263_E	1.242	0.55
187_D	270_D	1.236	0.55
146_F	149_S	1.234	0.55
154_K	168_L	1.230	0.54
118_V	138_E	1.219	0.54
260_I	269_Q	1.215	0.53
234_L	280_F	1.194	0.52
260_I	263_E	1.182	0.51
172_A	184_I	1.174	0.51
150_Y	154_K	1.172	0.51
110_Y	265_H	1.164	0.50
182_F	212_I	1.153	0.50
124_S	254_L	1.129	0.48
178_G	217_T	1.117	0.47
124_S	264_F	1.116	0.47
265_H	272_P	1.116	0.47
174_T	178_G	1.110	0.47
264_F	269_Q	1.107	0.47
234_L	250_P	1.100	0.46
121_V	263_E	1.098	0.46
138_E	232_Y	1.085	0.45
153_G	182_F	1.080	0.45
122_G	144_E	1.058	0.44
179_Y	215_P	1.028	0.42
254_L	269_Q	1.027	0.42
92_T	150_Y	1.026	0.42
122_G	240_G	1.026	0.42
238_C	258_E	1.009	0.41
56_I	276_R	1.005	0.40
218_T	221_S	1.005	0.40
254_L	264_F	0.995	0.40
119_I	233_L	0.983	0.39
137_A	258_E	0.981	0.39
150_Y	177_E	0.972	0.39
146_F	192_N	0.972	0.39
136_G	152_L	0.969	0.38
43_K	48_N	0.965	0.38
169_L	222_L	0.960	0.38
78_N	82_L	0.960	0.38
128_S	264_F	0.956	0.38
118_V	132_F	0.951	0.37
244_A	247_R	0.943	0.37
143_L	278_A	0.943	0.37
169_L	224_Q	0.937	0.36
263_E	272_P	0.934	0.36
262_L	280_F	0.930	0.36
223_I	252_E	0.925	0.36
157_I	162_L	0.921	0.36
254_L	257_I	0.921	0.36
113_S	118_V	0.914	0.35
156_N	263_E	0.910	0.35
260_I	272_P	0.900	0.34
174_T	219_L	0.893	0.34
40_L	51_F	0.891	0.34
123_A	233_L	0.890	0.34
234_L	248_D	0.888	0.34
103_E	110_Y	0.888	0.34
44_L	219_L	0.878	0.33
130_I	160_N	0.878	0.33
69_G	225_K	0.874	0.33
238_C	262_L	0.874	0.33
111_G	279_G	0.871	0.33
245_I	260_I	0.866	0.32
132_F	265_H	0.862	0.32
79_N	246_L	0.860	0.32
121_V	236_M	0.858	0.32
262_L	282_V	0.858	0.32
171_Y	215_P	0.855	0.32
126_A	248_D	0.854	0.32
118_V	257_I	0.854	0.32
145_P	236_M	0.848	0.31
177_E	215_P	0.847	0.31
272_P	276_R	0.847	0.31
255_N	258_E	0.844	0.31
243_Y	274_I	0.843	0.31
114_F	230_R	0.838	0.31
75_A	78_N	0.832	0.31
266_D	272_P	0.831	0.31
264_F	284_Y	0.824	0.30
92_T	278_A	0.824	0.30
73_K	79_N	0.823	0.30
74_E	139_K	0.814	0.30
234_L	260_I	0.813	0.30
156_N	160_N	0.807	0.29
263_E	273_D	0.806	0.29
140_V	160_N	0.797	0.29
234_L	266_D	0.793	0.29
127_D	264_F	0.781	0.28
68_K	113_S	0.776	0.28
99_G	103_E	0.771	0.27
140_V	235_K	0.771	0.27
106_E	110_Y	0.771	0.27
50_I	215_P	0.762	0.27
140_V	261_I	0.761	0.27
119_I	173_L	0.760	0.27
250_P	259_N	0.759	0.27
245_I	283_N	0.759	0.27
88_L	166_V	0.756	0.27
146_F	174_T	0.753	0.27
107_C	110_Y	0.751	0.26
222_L	275_L	0.748	0.26
63_L	135_N	0.747	0.26
219_L	251_A	0.741	0.26
270_D	275_L	0.740	0.26
182_F	241_C	0.740	0.26
140_V	271_L	0.736	0.26
232_Y	254_L	0.736	0.26
133_A	166_V	0.735	0.26
155_Y	158_K	0.735	0.26
126_A	240_G	0.733	0.26
245_I	262_L	0.730	0.25
245_I	263_E	0.728	0.25
238_C	271_L	0.727	0.25
236_M	242_E	0.726	0.25
136_G	140_V	0.725	0.25
192_N	267_Y	0.722	0.25
125_N	142_A	0.721	0.25
172_A	219_L	0.720	0.25
232_Y	282_V	0.717	0.25
236_M	262_L	0.713	0.25
41_E	52_L	0.712	0.25
162_L	168_L	0.711	0.25
70_W	228_I	0.709	0.24
215_P	244_A	0.709	0.24
127_D	236_M	0.707	0.24
263_E	282_V	0.706	0.24
127_D	132_F	0.706	0.24
233_L	260_I	0.705	0.24
154_K	256_K	0.702	0.24
242_E	265_H	0.701	0.24
97_D	106_E	0.700	0.24
119_I	228_I	0.700	0.24
124_S	232_Y	0.695	0.24
214_V	225_K	0.692	0.24
74_E	119_I	0.690	0.24
238_C	248_D	0.689	0.24
219_L	253_V	0.688	0.24
142_A	145_P	0.686	0.23
84_K	157_I	0.678	0.23
70_W	78_N	0.677	0.23
129_S	257_I	0.675	0.23
101_I	110_Y	0.675	0.23
129_S	160_N	0.674	0.23
261_I	272_P	0.674	0.23
124_S	149_S	0.673	0.23
45_K	63_L	0.670	0.23
79_N	82_L	0.670	0.23
145_P	235_K	0.664	0.22
153_G	238_C	0.662	0.22
59_L	162_L	0.661	0.22
120_D	144_E	0.661	0.22
254_L	261_I	0.659	0.22
123_A	190_N	0.654	0.22
144_E	237_D	0.654	0.22
73_K	82_L	0.652	0.22
219_L	271_L	0.651	0.22
180_V	216_T	0.650	0.22
236_M	260_I	0.650	0.22
68_K	80_A	0.650	0.22
254_L	275_L	0.648	0.22
261_I	265_H	0.648	0.22
263_E	268_P	0.644	0.22
67_K	76_D	0.643	0.22
116_G	225_K	0.643	0.22
120_D	123_A	0.642	0.22
40_L	44_L	0.642	0.22
50_I	164_N	0.639	0.21
110_Y	239_E	0.638	0.21
137_A	253_V	0.637	0.21
265_H	271_L	0.633	0.21
95_G	279_G	0.631	0.21
126_A	144_E	0.630	0.21
256_K	281_N	0.628	0.21
64_S	158_K	0.627	0.21
237_D	271_L	0.626	0.21
164_N	184_I	0.626	0.21
210_Q	284_Y	0.624	0.21
72_V	77_E	0.623	0.21
102_D	230_R	0.622	0.21
154_K	258_E	0.618	0.21
194_V	216_T	0.618	0.21
90_I	142_A	0.617	0.20
260_I	275_L	0.615	0.20
40_L	45_K	0.612	0.20
113_S	132_F	0.611	0.20
135_N	166_V	0.607	0.20
150_Y	222_L	0.607	0.20
232_Y	263_E	0.603	0.20
123_A	231_V	0.602	0.20
220_A	234_L	0.602	0.20
127_D	265_H	0.601	0.20
147_P	157_I	0.600	0.20
128_S	138_E	0.600	0.20
128_S	236_M	0.599	0.20
124_S	269_Q	0.598	0.20
164_N	172_A	0.598	0.20
265_H	285_E	0.597	0.20
258_E	287_K	0.595	0.20
66_L	134_T	0.593	0.20
276_R	279_G	0.592	0.19
262_L	281_N	0.592	0.19
194_V	213_K	0.591	0.19
106_E	253_V	0.590	0.19
271_L	277_K	0.589	0.19
176_Y	219_L	0.589	0.19
122_G	237_D	0.585	0.19
264_F	276_R	0.582	0.19
132_F	231_V	0.576	0.19
124_S	138_E	0.574	0.19
264_F	272_P	0.573	0.19
144_E	240_G	0.571	0.19
132_F	211_K	0.570	0.19
67_K	141_I	0.569	0.19
103_E	106_E	0.569	0.19
62_L	78_N	0.568	0.19
238_C	263_E	0.568	0.19
75_A	79_N	0.567	0.19
145_P	172_A	0.567	0.19
245_I	272_P	0.567	0.19
222_L	226_Y	0.564	0.18
145_P	277_K	0.563	0.18
137_A	143_L	0.561	0.18
237_D	265_H	0.558	0.18
50_I	246_L	0.557	0.18
159_I	286_N	0.557	0.18
262_L	275_L	0.557	0.18
260_I	287_K	0.556	0.18
173_L	222_L	0.554	0.18
233_L	259_N	0.553	0.18
77_E	80_A	0.553	0.18
182_F	207_K	0.553	0.18
174_T	182_F	0.552	0.18
92_T	143_L	0.551	0.18
147_P	215_P	0.548	0.18
141_I	171_Y	0.546	0.18
135_N	279_G	0.545	0.18
44_L	48_N	0.544	0.18
62_L	66_L	0.544	0.18
238_C	268_P	0.544	0.18
236_M	269_Q	0.540	0.18
153_G	168_L	0.539	0.17
143_L	247_R	0.538	0.17
140_V	237_D	0.534	0.17
137_A	241_C	0.532	0.17
139_K	167_I	0.531	0.17
269_Q	286_N	0.527	0.17
151_E	154_K	0.527	0.17
125_N	287_K	0.527	0.17
142_A	153_G	0.526	0.17
234_L	245_I	0.525	0.17
61_A	227_N	0.524	0.17
242_E	245_I	0.522	0.17
187_D	190_N	0.522	0.17
128_S	133_A	0.521	0.17
43_K	49_R	0.521	0.17
261_I	264_F	0.520	0.17
268_P	280_F	0.520	0.17
119_I	168_L	0.520	0.17
123_A	168_L	0.519	0.17
52_L	85_E	0.518	0.17
58_D	121_V	0.518	0.17
66_L	217_T	0.518	0.17
125_N	160_N	0.518	0.17
220_A	238_C	0.517	0.17
139_K	157_I	0.515	0.17
123_A	162_L	0.513	0.17
63_L	277_K	0.511	0.16
118_V	271_L	0.511	0.16
88_L	115_K	0.511	0.16
85_E	155_Y	0.510	0.16
164_N	280_F	0.509	0.16
71_K	74_E	0.507	0.16
91_R	246_L	0.507	0.16
161_N	172_A	0.506	0.16
48_N	53_K	0.506	0.16
59_L	147_P	0.506	0.16
179_Y	277_K	0.505	0.16
106_E	164_N	0.505	0.16
157_I	207_K	0.503	0.16
59_L	221_S	0.503	0.16
45_K	50_I	0.501	0.16
261_I	271_L	0.501	0.16
118_V	287_K	0.500	0.16
90_I	155_Y	0.500	0.16

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2py6A	4	0.8571	100	0.504	Contact Map
3gnlA	1	0.5216	96.2	0.891	Contact Map
3kr9A	1	0.515	96.1	0.891	Contact Map
3lecA	2	0.5249	95.8	0.894	Contact Map
3k6rA	1	0.7807	95.3	0.898	Contact Map
3lpmA	2	0.598	95.2	0.899	Contact Map
4lwoB	2	0.6412	93.9	0.905	Contact Map
4qdjA	1	0.6744	93.9	0.905	Contact Map
1wy7A	1	0.6113	93.7	0.906	Contact Map
2yxdA	4	0.5714	93.6	0.906	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0089 seconds.