GREMLIN Database
Q7LXA5 - Peptidase, putative
UniProt: Q7LXA5 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 606 (513)
Sequences: 1469 (1242)
Seq/√Len: 54.9

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
433_G489_S8.7371.00
485_I523_T6.7021.00
423_E430_S5.1811.00
394_L520_A4.6741.00
83_E90_Q4.3601.00
257_I311_S4.0761.00
549_I585_P3.9611.00
463_A468_I3.9461.00
302_G513_W3.8921.00
449_G582_V3.8231.00
241_N589_N3.5581.00
108_R112_N3.5201.00
565_P580_N3.2501.00
453_S582_V3.1111.00
90_Q93_H3.0641.00
466_Y544_I2.9721.00
502_L522_M2.8781.00
138_T141_N2.8471.00
57_L139_V2.8421.00
185_L193_V2.8371.00
527_V545_S2.8071.00
489_S519_A2.7871.00
392_S429_T2.7291.00
505_V510_L2.7001.00
359_I395_A2.6611.00
65_I142_I2.6371.00
194_L378_M2.6131.00
394_L527_V2.5701.00
314_F525_A2.5381.00
261_G322_I2.5151.00
259_I311_S2.3881.00
380_H425_D2.3861.00
564_I589_N2.3841.00
429_T546_Y2.3481.00
275_F310_W2.3191.00
269_V286_H2.3171.00
358_S520_A2.2461.00
73_N76_S2.2431.00
552_S561_V2.2251.00
449_G583_T2.2191.00
185_L189_I2.2111.00
448_S568_S2.2011.00
396_A520_A2.1961.00
96_T99_Q2.1851.00
392_S545_S2.1481.00
589_N592_A2.1481.00
394_L523_T2.1161.00
259_I358_S2.0981.00
376_L460_V2.0911.00
53_F151_N2.0901.00
549_I563_W2.0501.00
258_A323_V2.0101.00
29_A33_A2.0091.00
433_G450_W1.9931.00
476_P479_V1.9751.00
465_I468_I1.9371.00
242_F526_M1.9251.00
307_D399_D1.9231.00
112_N116_K1.9211.00
564_I587_T1.9181.00
78_Q384_L1.9141.00
533_R594_V1.8680.99
233_P313_A1.8610.99
30_Q33_A1.8530.99
454_T482_Y1.8500.99
394_L429_T1.8380.99
481_T579_W1.8370.99
257_I524_A1.8340.99
104_Y385_Q1.8160.99
306_L513_W1.7870.99
56_P151_N1.7340.99
274_S505_V1.7300.99
65_I135_F1.7230.99
305_E309_E1.7230.99
430_S482_Y1.7180.99
79_S83_E1.6930.99
262_V359_I1.6840.99
137_G142_I1.6640.99
54_V154_Y1.6590.99
256_N321_T1.6310.99
450_W489_S1.6260.98
69_L114_L1.6190.98
533_R590_A1.6150.98
258_A357_I1.5710.98
87_S551_E1.5670.98
92_H534_L1.5520.98
548_G597_L1.5440.98
276_W312_G1.5400.98
64_Y136_S1.5320.98
97_P101_R1.5240.98
382_I385_Q1.5220.98
429_T545_S1.5100.98
416_Y459_V1.4990.97
386_A393_V1.4950.97
369_A372_Y1.4940.97
143_E149_Y1.4820.97
56_P149_Y1.4760.97
233_P279_Y1.4760.97
291_Y295_V1.4640.97
59_S140_G1.4630.97
426_P461_Y1.4550.97
293_G340_N1.4540.97
463_A481_T1.4470.97
562_A596_D1.4460.97
370_A377_D1.4450.97
420_W423_E1.4360.97
466_Y546_Y1.4310.97
85_Y92_H1.4300.97
450_W500_F1.4260.97
258_A354_P1.4180.96
315_A525_A1.4080.96
362_T520_A1.4060.96
265_S304_N1.4040.96
355_N541_L1.4010.96
377_D381_N1.3930.96
450_W514_Y1.3880.96
500_F514_Y1.3850.96
77_L388_A1.3810.96
29_A32_Q1.3790.96
312_G320_V1.3790.96
266_F475_T1.3750.96
394_L545_S1.3720.96
310_W522_M1.3680.96
291_Y324_F1.3590.95
259_I308_A1.3500.95
303_E307_D1.3430.95
256_N355_N1.3430.95
362_T396_A1.3380.95
242_F529_L1.3360.95
397_S453_S1.3250.95
310_W518_G1.3170.95
28_I32_Q1.3160.95
357_I391_I1.3100.94
60_S140_G1.3100.94
544_I547_Q1.3060.94
355_N535_G1.2990.94
81_L427_Y1.2970.94
274_S278_L1.2850.94
311_S358_S1.2820.94
260_E357_I1.2800.94
356_V394_L1.2740.93
347_Y351_Y1.2660.93
77_L384_L1.2660.93
81_L387_A1.2650.93
420_W454_T1.2540.93
267_V287_L1.2540.93
257_I525_A1.2520.93
431_V519_A1.2470.93
143_E151_N1.2420.93
278_L510_L1.2410.93
233_P310_W1.2400.93
396_A420_W1.2400.93
266_F301_S1.2380.92
380_H421_Y1.2370.92
261_G304_N1.2340.92
485_I527_V1.2340.92
527_V530_A1.2320.92
88_A91_F1.2280.92
268_N301_S1.2270.92
63_L139_V1.2250.92
56_P143_E1.2240.92
113_S189_I1.2090.92
304_N361_V1.2060.91
304_N324_F1.2050.91
304_N322_I1.2040.91
185_L190_G1.2030.91
527_V542_Y1.2030.91
475_T479_V1.2020.91
257_I528_A1.1990.91
503_P510_L1.1980.91
419_I459_V1.1960.91
82_N427_Y1.1960.91
76_S79_S1.1920.91
435_F500_F1.1910.91
564_I592_A1.1840.91
146_F199_I1.1830.91
28_I31_S1.1790.91
513_W518_G1.1710.90
30_Q34_Q1.1690.90
562_A593_M1.1680.90
76_S80_Y1.1630.90
471_L481_T1.1580.90
93_H540_A1.1550.90
387_A544_I1.1500.89
36_Y40_T1.1490.89
146_F196_V1.1440.89
356_V527_V1.1390.89
358_S521_P1.1350.89
123_L135_F1.1350.89
118_L135_F1.1330.89
83_E86_L1.1300.89
27_I31_S1.1290.89
62_T136_S1.1280.88
315_A528_A1.1220.88
31_S34_Q1.1210.88
378_M382_I1.1180.88
517_S521_P1.1130.88
269_V273_Y1.1100.88
529_L532_T1.1080.88
255_S318_A1.1050.87
580_N583_T1.0990.87
487_F587_T1.0940.87
255_S535_G1.0860.86
101_R129_Y1.0820.86
110_Y192_Y1.0780.86
80_Y90_Q1.0740.86
487_F523_T1.0710.86
199_I202_L1.0710.86
95_L103_Y1.0670.86
530_A594_V1.0660.85
337_N340_N1.0660.85
307_D521_P1.0650.85
363_V368_L1.0650.85
260_E359_I1.0620.85
397_S430_S1.0600.85
84_I94_W1.0580.85
341_Y357_I1.0580.85
307_D360_S1.0570.85
137_G141_N1.0550.85
480_R484_D1.0550.85
85_Y91_F1.0540.85
150_I199_I1.0500.85
66_A132_I1.0410.84
83_E88_A1.0410.84
585_P593_M1.0350.84
283_R316_P1.0300.83
336_G363_V1.0290.83
271_D508_G1.0260.83
420_W430_S1.0250.83
563_W593_M1.0250.83
402_Y417_N1.0190.83
80_Y84_I1.0190.83
455_G571_N1.0180.83
251_T317_A1.0160.83
290_I321_T1.0160.83
137_G145_A1.0160.83
303_E399_D1.0150.83
83_E99_Q1.0130.82
488_V522_M1.0120.82
431_V485_I1.0110.82
364_P404_S1.0110.82
255_S531_G1.0080.82
68_L195_G1.0040.82
400_W404_S1.0010.82
76_S103_Y1.0000.82
356_V531_G1.0000.82
383_M422_P0.9980.81
404_S420_W0.9950.81
486_A489_S0.9930.81
368_L376_L0.9930.81
303_E521_P0.9910.81
534_L539_F0.9900.81
74_L384_L0.9890.81
28_I33_A0.9840.81
107_S110_Y0.9830.80
354_P391_I0.9820.80
396_A519_A0.9810.80
48_I51_S0.9780.80
94_W544_I0.9780.80
111_V130_G0.9770.80
569_G575_A0.9750.80
420_W482_Y0.9740.80
535_G540_A0.9690.79
253_G317_A0.9680.79
261_G267_V0.9660.79
575_A580_N0.9650.79
531_G546_Y0.9640.79
75_A79_S0.9630.79
403_E406_H0.9630.79
553_P560_K0.9630.79
501_G512_V0.9590.79
370_A460_V0.9530.78
553_P585_P0.9520.78
32_Q35_Y0.9480.78
341_Y345_Y0.9410.77
552_S560_K0.9380.77
363_V424_S0.9380.77
233_P275_F0.9340.77
139_V150_I0.9320.77
223_S226_V0.9320.77
235_T380_H0.9310.77
257_I320_V0.9310.77
362_T423_E0.9310.77
264_E304_N0.9310.77
423_E482_Y0.9280.76
262_V334_L0.9270.76
397_S583_T0.9270.76
553_P561_V0.9260.76
567_T575_A0.9220.76
31_S35_Y0.9210.76
41_S44_Q0.9210.76
303_E306_L0.9190.76
429_T527_V0.9170.76
380_H427_Y0.9160.76
531_G534_L0.9160.76
565_P578_G0.9120.75
364_P405_D0.9020.74
241_N591_Y0.9010.74
122_N141_N0.8970.74
422_P428_V0.8960.74
235_T425_D0.8920.74
239_Y446_E0.8910.73
485_I549_I0.8880.73
142_I150_I0.8880.73
308_A396_A0.8880.73
503_P512_V0.8860.73
349_V352_L0.8860.73
553_P562_A0.8850.73
360_S521_P0.8800.73
465_I469_T0.8790.72
271_D305_E0.8750.72
101_R105_Y0.8730.72
42_S371_Y0.8720.72
272_I308_A0.8700.72
108_R130_G0.8700.72
123_L145_A0.8680.72
27_I33_A0.8680.72
421_Y461_Y0.8670.71
100_F388_A0.8660.71
383_M404_S0.8660.71
70_N110_Y0.8660.71
123_L137_G0.8640.71
240_F434_I0.8610.71
241_N564_I0.8610.71
28_I34_Q0.8590.71
279_Y503_P0.8570.71
419_I482_Y0.8560.70
234_I237_E0.8560.70
338_L379_I0.8540.70
224_G238_Q0.8540.70
188_N191_K0.8530.70
230_I503_P0.8510.70
258_A321_T0.8490.70
335_V363_V0.8490.70
147_N184_S0.8470.70
36_Y39_Q0.8470.70
267_V272_I0.8430.69
84_I92_H0.8350.69
368_L372_Y0.8320.68
402_Y570_N0.8300.68
318_A528_A0.8290.68
592_A595_Y0.8290.68
80_Y95_L0.8270.68
320_V323_V0.8270.68
399_D521_P0.8260.68
95_L388_A0.8250.68
253_G536_A0.8250.68
39_Q42_S0.8220.67
65_I146_F0.8200.67
111_V126_L0.8190.67
425_D461_Y0.8180.67
86_L551_E0.8180.67
485_I563_W0.8160.67
100_F385_Q0.8160.67
262_V396_A0.8150.67
186_P189_I0.8150.67
198_G380_H0.8130.66
237_E314_F0.8130.66
518_G522_M0.8110.66
307_D517_S0.8080.66
487_F522_M0.8070.66
252_G536_A0.8060.66
65_I319_N0.8050.66
402_Y572_P0.8050.66
278_L505_V0.8040.66
250_Y536_A0.8030.66
313_A523_T0.8020.65
566_I569_G0.8020.65
563_W585_P0.8010.65
591_Y594_V0.7970.65
250_Y254_G0.7970.65
459_V476_P0.7960.65
189_I525_A0.7950.65
315_A318_A0.7940.65
523_T588_Y0.7940.65
501_G514_Y0.7920.64
462_P465_I0.7910.64
98_S351_Y0.7890.64
260_E341_Y0.7870.64
84_I95_L0.7870.64
395_A430_S0.7840.64
255_S355_N0.7840.64
396_A430_S0.7840.64
155_Y158_K0.7800.63
280_G313_A0.7800.63
267_V304_N0.7780.63
80_Y103_Y0.7780.63
402_Y573_L0.7760.63
196_V199_I0.7760.63
33_A36_Y0.7740.63
297_T300_Q0.7730.63
139_V143_E0.7720.62
303_E517_S0.7700.62
481_T581_Y0.7690.62
115_I119_E0.7690.62
335_V369_A0.7680.62
383_M428_V0.7680.62
198_G425_D0.7680.62
108_R124_Q0.7660.62
323_V354_P0.7660.62
110_Y113_S0.7630.62
236_I488_V0.7620.61
259_I322_I0.7600.61
288_N319_N0.7570.61
81_L100_F0.7560.61
352_L389_Q0.7560.61
433_G486_A0.7550.61
257_I357_I0.7550.61
67_V135_F0.7550.61
548_G593_M0.7540.61
421_Y425_D0.7540.61
31_S39_Q0.7530.60
447_I564_I0.7520.60
433_G519_A0.7510.60
111_V115_I0.7500.60
434_I447_I0.7470.60
362_T420_W0.7470.60
75_A78_Q0.7460.60
560_K563_W0.7460.60
523_T526_M0.7440.60
360_S399_D0.7430.59
308_A526_M0.7410.59
545_S597_L0.7410.59
95_L99_Q0.7400.59
59_S143_E0.7400.59
152_V178_S0.7350.59
91_F362_T0.7330.58
348_M385_Q0.7310.58
121_Y145_A0.7290.58
67_V193_V0.7290.58
457_N479_V0.7290.58
146_F150_I0.7280.58
96_T258_A0.7270.58
277_Q284_T0.7260.58
91_F94_W0.7260.58
148_T151_N0.7240.57
116_K120_S0.7240.57
242_F356_V0.7210.57
62_T140_G0.7210.57
289_V324_F0.7180.57
185_L196_V0.7180.57
521_P524_A0.7170.57
88_A94_W0.7170.57
250_Y532_T0.7160.57
543_H546_Y0.7120.56
30_Q38_I0.7100.56
242_F460_V0.7070.56
39_Q187_F0.7070.56
272_I312_G0.7060.56
346_Y349_V0.7060.56
139_V142_I0.7050.55
395_A402_Y0.7040.55
474_F574_P0.7030.55
82_N466_Y0.7030.55
303_E360_S0.7010.55
157_F428_V0.7000.55
487_F588_Y0.7000.55
94_W531_G0.6990.55
104_Y341_Y0.6970.55
117_Y146_F0.6950.54
140_G144_K0.6940.54
399_D517_S0.6920.54
228_K436_L0.6920.54
419_I424_S0.6910.54
185_L403_E0.6900.54
126_L130_G0.6900.54
397_S449_G0.6890.54
376_L421_Y0.6890.54
414_G418_T0.6890.54
236_I575_A0.6880.54
471_L474_F0.6880.54
533_R537_L0.6870.54
274_S503_P0.6820.53
153_Y180_N0.6820.53
38_I41_S0.6820.53
379_I421_Y0.6800.53
58_N61_Q0.6790.53
268_N298_G0.6790.53
523_T527_V0.6770.52
32_Q462_P0.6770.52
38_I147_N0.6770.52
257_I315_A0.6760.52
337_N372_Y0.6750.52
332_P337_N0.6740.52
311_S320_V0.6730.52
244_L250_Y0.6730.52
311_S525_A0.6730.52
359_I520_A0.6730.52
143_E148_T0.6720.52
230_I486_A0.6700.52
239_Y488_V0.6700.52
34_Q37_Y0.6680.52
426_P432_G0.6670.51
55_E89_P0.6670.51
365_E404_S0.6660.51
262_V341_Y0.6640.51
552_S592_A0.6630.51
350_N353_N0.6630.51
530_A542_Y0.6630.51
387_A393_V0.6610.51
28_I35_Y0.6610.51
436_L488_V0.6610.51
338_L342_Y0.6600.51
216_L219_V0.6590.51
116_K140_G0.6580.50
35_Y38_I0.6570.50
31_S36_Y0.6570.50
239_Y587_T0.6550.50
407_P413_I0.6550.50
98_S102_E0.6540.50
463_A471_L0.6520.50
590_A594_V0.6520.50
65_I137_G0.6520.50
365_E458_S0.6520.50
387_A466_Y0.6500.50
100_F104_Y0.6500.50
200_D361_V0.6500.50
298_G301_S0.6480.49
263_P336_G0.6470.49
342_Y383_M0.6470.49
80_Y99_Q0.6460.49
254_G318_A0.6460.49
108_R549_I0.6420.49
27_I34_Q0.6420.49
263_P363_V0.6400.49
40_T43_P0.6390.48
239_Y579_W0.6390.48
95_L189_I0.6380.48
227_S235_T0.6360.48
336_G367_F0.6360.48
91_F383_M0.6350.48
357_I386_A0.6340.48
519_A522_M0.6340.48
215_H218_M0.6320.48
115_I126_L0.6310.48
435_F518_G0.6300.47
209_V292_F0.6290.47
457_N581_Y0.6290.47
81_L384_L0.6270.47
118_L123_L0.6270.47
37_Y147_N0.6230.47
97_P385_Q0.6230.47
270_S468_I0.6220.47
70_N75_A0.6220.47
526_M563_W0.6210.46
426_P434_I0.6210.46
105_Y130_G0.6210.46
86_L91_F0.6200.46
356_V392_S0.6200.46
122_N553_P0.6200.46
331_G334_L0.6180.46
129_Y520_A0.6180.46
422_P429_T0.6180.46
335_V338_L0.6170.46
138_T142_I0.6170.46
348_M352_L0.6170.46
260_E263_P0.6160.46
358_S524_A0.6160.46
279_Y310_W0.6150.46
260_E466_Y0.6150.46
382_I454_T0.6140.46
362_T424_S0.6120.46
280_G283_R0.6120.46
214_W217_P0.6110.45
112_N120_S0.6110.45
27_I36_Y0.6110.45
91_F597_L0.6110.45
242_F314_F0.6090.45
335_V368_L0.6090.45
362_T521_P0.6080.45
27_I32_Q0.6060.45
230_I512_V0.6060.45
261_G324_F0.6060.45
217_P220_K0.6040.45
567_T580_N0.6040.45
591_Y596_D0.6040.45
437_N448_S0.6040.45
193_V289_V0.6030.45
310_W502_L0.6030.45
504_L512_V0.6030.45
372_Y466_Y0.6020.44
310_W452_Y0.6010.44
394_L524_A0.6010.44
240_F447_I0.6000.44
337_N369_A0.5990.44
360_S517_S0.5970.44
71_F381_N0.5960.44
52_V156_P0.5960.44
432_G483_P0.5960.44
448_S514_Y0.5940.44
419_I457_N0.5940.44
352_L355_N0.5940.44
470_S594_V0.5940.44
332_P335_V0.5930.44
267_V297_T0.5930.44
107_S192_Y0.5920.43
592_A596_D0.5920.43
394_L463_A0.5920.43
527_V531_G0.5900.43
337_N379_I0.5900.43
421_Y518_G0.5880.43
286_H289_V0.5870.43
150_I201_S0.5860.43
420_W424_S0.5860.43
112_N185_L0.5860.43
359_I402_Y0.5850.43
282_P316_P0.5850.43
469_T472_I0.5830.42
279_Y514_Y0.5830.42
28_I38_I0.5810.42
336_G372_Y0.5810.42
323_V357_I0.5800.42
285_G290_I0.5790.42
325_S338_L0.5790.42
566_I575_A0.5780.42
274_S277_Q0.5780.42
435_F514_Y0.5770.42
274_S510_L0.5760.42
380_H386_A0.5760.42
242_F525_A0.5760.42
303_E515_G0.5760.42
306_L362_T0.5750.42
239_Y436_L0.5740.42
65_I202_L0.5730.41
110_Y393_V0.5730.41
108_R430_S0.5730.41
142_I309_E0.5720.41
262_V338_L0.5710.41
551_E561_V0.5710.41
531_G540_A0.5710.41
384_L532_T0.5700.41
89_P219_V0.5690.41
553_P596_D0.5690.41
506_F511_F0.5690.41
239_Y357_I0.5690.41
193_V277_Q0.5670.41
65_I597_L0.5660.41
431_V582_V0.5660.41
433_G514_Y0.5660.41
123_L528_A0.5650.41
354_P389_Q0.5650.41
72_T107_S0.5650.41
531_G544_I0.5640.40
67_V114_L0.5640.40
526_M588_Y0.5620.40
290_I323_V0.5610.40
268_N305_E0.5610.40
225_L465_I0.5610.40
102_E190_G0.5600.40
355_N528_A0.5600.40
565_P583_T0.5590.40
455_G585_P0.5590.40
502_L518_G0.5580.40
560_K585_P0.5580.40
298_G507_Q0.5580.40
258_A369_A0.5580.40
396_A518_G0.5570.40
366_S406_H0.5570.40
249_G252_G0.5560.40
92_H544_I0.5550.40
244_L248_R0.5550.40
46_T53_F0.5550.40
485_I574_P0.5530.39
270_S427_Y0.5530.39
272_I581_Y0.5530.39
81_L84_I0.5520.39
68_L71_F0.5510.39
77_L532_T0.5510.39
183_P196_V0.5510.39
562_A588_Y0.5510.39
29_A35_Y0.5500.39
197_V200_D0.5500.39
146_F189_I0.5490.39
386_A391_I0.5490.39
40_T45_Y0.5480.39
38_I42_S0.5480.39
237_E280_G0.5470.39
276_W281_I0.5470.39
384_L388_A0.5460.39
47_I391_I0.5450.39
56_P108_R0.5440.38
148_T182_T0.5440.38
273_Y276_W0.5440.38
336_G346_Y0.5420.38
417_N573_L0.5400.38
43_P182_T0.5390.38
52_V121_Y0.5390.38
310_W513_W0.5380.38
264_E449_G0.5380.38
452_Y582_V0.5370.38
119_E125_F0.5360.38
542_Y548_G0.5360.38
68_L132_I0.5340.37
75_A553_P0.5340.37
292_F585_P0.5340.37
135_F393_V0.5330.37
252_G318_A0.5330.37
227_S238_Q0.5330.37
258_A509_Q0.5320.37
98_S109_S0.5310.37
349_V386_A0.5310.37
243_T590_A0.5300.37
287_L299_G0.5300.37
333_Q338_L0.5300.37
291_Y296_T0.5290.37
193_V542_Y0.5290.37
36_Y45_Y0.5270.37
74_L381_N0.5270.37
457_N474_F0.5270.37
575_A578_G0.5270.37
287_L593_M0.5260.37
542_Y562_A0.5250.37
146_F198_G0.5240.36
305_E466_Y0.5240.36
51_S202_L0.5240.36
73_N103_Y0.5230.36
78_Q427_Y0.5230.36
95_L529_L0.5230.36
529_L533_R0.5220.36
384_L545_S0.5210.36
101_R196_V0.5200.36
71_F74_L0.5200.36
232_S487_F0.5190.36
39_Q45_Y0.5190.36
144_K189_I0.5180.36
189_I366_S0.5180.36
264_E324_F0.5180.36
214_W219_V0.5170.36
63_L142_I0.5170.36
421_Y426_P0.5170.36
111_V128_N0.5170.36
98_S116_K0.5160.36
457_N481_T0.5150.36
109_S192_Y0.5150.36
99_Q102_E0.5150.36
70_N109_S0.5140.35
193_V216_L0.5130.35
392_S523_T0.5130.35
179_N354_P0.5130.35
279_Y510_L0.5120.35
359_I383_M0.5120.35
405_D418_T0.5120.35
43_P50_G0.5110.35
157_F462_P0.5110.35
40_T188_N0.5110.35
394_L563_W0.5100.35
526_M590_A0.5100.35
591_Y595_Y0.5100.35
362_T365_E0.5100.35
63_L135_F0.5090.35
400_W453_S0.5090.35
117_Y145_A0.5070.35
368_L421_Y0.5070.35
295_V391_I0.5070.35
459_V477_V0.5060.35
80_Y104_Y0.5060.35
364_P418_T0.5060.35
518_G524_A0.5050.35
548_G553_P0.5050.35
363_V367_F0.5050.35
119_E122_N0.5050.35
115_I125_F0.5050.35
314_F553_P0.5030.34
52_V73_N0.5030.34
564_I593_M0.5030.34
345_Y389_Q0.5020.34
322_I361_V0.5010.34
530_A593_M0.5010.34
337_N363_V0.5010.34
117_Y353_N0.5000.34
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3edyA 1 0.8482 100 0.335 Contact Map
1t1eA 1 0.8366 100 0.373 Contact Map
1ga6A 1 0.5726 100 0.586 Contact Map
4mzdA 1 0.5116 99.9 0.841 Contact Map
2ixtA 1 0.4868 99.9 0.842 Contact Map
2z30A 1 0.4752 99.9 0.853 Contact Map
4h6wA 1 0.4406 99.9 0.854 Contact Map
3wiuA 2 0.5957 99.9 0.857 Contact Map
3t41A 1 0.6353 99.9 0.857 Contact Map
2iy9A 1 0.4802 99.9 0.859 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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