Q7LX99 - SULSO - GREMLIN Contacts

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Q7LX99 - Glycogen debranching enzyme (TreX)

UniProt:	Q7LX99	Sequences: MALFFRTRDRPLRPGDPYPLGSNWIEDDDGVNFSLFSENAEKVELLLYSLTNQKYPKEIIEVKNKTGDIWHVFVPGLRPGQLYAYRVYGPYKPELGLRFNPNKVLIDPYAKAINGSVIWNDAVFGYKIGDQNQDLTYDERDSGEYVPKSVVINPYFEWDDEDFIKGKKVPLKDTVIYEVHVKGFTKLRLDLPENIRGTYEGLASEQMISYLKDLGITTVELMPVFHFIDQRFLTDKGLTNYWGYDPINFFSPECRYSSTGCLGGQVLSFKKMVNELHNAGIEVIIDVVYNHTAEGNHLGPTLSFRGIDNTAYYMLQPDNKRYYLDFTGTGNTLNLSHPRVIQMVLDSLRYWVTEMHVDGFRFDLAAALARELYSVNMLNTFFIALQQDPILSQVKLIAEPWDVGQGGYQVGNFPYQWAEWNGKYRDSIRRFWRGEALPYSEIANRLLGSPDIYLGNNKTPFASINYVTSHDGFTLEDLVSYNQKHNEANGFNNQDGMNENYSWNCGAEGPTNDQNVVICREKQKRNFMITLLVSQGTPMILGGDELSRTQRGNNNAFCQDNEITWFDWNLDERKSKFLEFVKKMIQFYRAHPAFRRERYFQGKKLFGMPLKDVTFYTLEGREVDEKTWSSPTQLVIFVLEGSVMDEINMYGERIADDSFLIILNANPNNVKVKFPKGKWELVISSYLREIKPEERIIEGEKELEIEGRTALVYRRIEL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	718 (598)
Sequences:	4359 (2850)
Seq/√Len:	116.5

ECOLI - GLGX GLGB MALZ YGAQ
BACSU - PULA GLGB BBMA
SULSO - Q7LX99 TREZ

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
213_D	582_K	4.007	1.00
35_L	307_I	3.832	1.00
269_F	273_V	3.621	1.00
179_V	184_F	3.587	1.00
161_E	356_H	3.519	1.00
158_W	356_H	3.517	1.00
62_V	72_V	3.465	1.00
289_Y	347_S	3.385	1.00
352_V	394_V	3.209	1.00
200_E	271_K	3.134	1.00
275_E	278_N	3.022	1.00
350_Y	355_M	2.954	1.00
43_V	87_V	2.823	1.00
27_D	73_F	2.796	1.00
30_G	73_F	2.776	1.00
87_V	307_I	2.773	1.00
35_L	43_V	2.755	1.00
42_K	61_E	2.739	1.00
586_Q	590_A	2.680	1.00
212_K	279_A	2.625	1.00
547_S	577_F	2.601	1.00
82_L	114_N	2.521	1.00
44_E	88_Y	2.501	1.00
33_F	85_Y	2.496	1.00
174_T	218_T	2.484	1.00
219_V	276_L	2.464	1.00
224_V	269_F	2.464	1.00
35_L	87_V	2.437	1.00
169_V	218_T	2.426	1.00
528_M	581_V	2.402	1.00
476_E	524_K	2.394	1.00
200_E	268_S	2.389	1.00
184_F	207_M	2.366	1.00
218_T	284_I	2.354	1.00
213_D	578_L	2.346	1.00
173_D	595_R	2.345	1.00
182_K	186_K	2.343	1.00
424_Y	534_S	2.331	1.00
542_G	566_F	2.305	1.00
156_F	271_K	2.248	1.00
570_L	574_K	2.232	1.00
269_F	272_M	2.211	1.00
567_D	570_L	2.203	1.00
532_L	585_I	2.200	1.00
22_S	31_V	2.191	1.00
427_S	441_E	2.147	1.00
339_R	342_Q	2.118	1.00
634_L	637_F	2.113	1.00
333_L	340_V	2.107	1.00
271_K	275_E	2.081	1.00
209_S	279_A	2.077	1.00
270_K	354_E	2.074	1.00
304_F	343_M	2.055	1.00
159_D	274_N	2.042	1.00
47_L	60_I	2.040	1.00
74_V	77_L	2.037	1.00
277_H	358_D	2.028	1.00
175_V	585_I	2.028	1.00
199_Y	257_S	2.027	1.00
524_K	547_S	2.017	1.00
662_I	672_V	2.016	1.00
528_M	540_I	2.006	1.00
193_E	196_R	1.999	1.00
191_L	196_R	1.985	1.00
174_T	217_T	1.965	1.00
476_E	510_P	1.935	1.00
546_L	566_F	1.932	1.00
578_L	582_K	1.924	1.00
579_E	582_K	1.911	1.00
292_T	313_Y	1.905	1.00
97_L	310_T	1.901	1.00
373_Y	376_N	1.884	1.00
521_E	524_K	1.863	1.00
60_I	72_V	1.862	1.00
113_I	248_N	1.852	1.00
476_E	480_S	1.841	1.00
106_I	113_I	1.839	1.00
551_R	563_I	1.837	1.00
31_V	77_L	1.813	1.00
269_F	357_V	1.812	1.00
226_H	254_C	1.810	1.00
44_E	86_R	1.806	1.00
84_A	104_V	1.802	1.00
409_Q	412_N	1.780	1.00
183_G	241_Y	1.778	1.00
637_F	640_E	1.771	1.00
42_K	88_Y	1.764	1.00
248_N	251_S	1.760	1.00
335_L	344_V	1.760	1.00
179_V	202_L	1.759	1.00
44_E	59_I	1.737	1.00
179_V	219_V	1.733	1.00
528_M	584_M	1.731	1.00
342_Q	346_D	1.730	1.00
158_W	161_E	1.709	1.00
43_V	307_I	1.705	1.00
184_F	202_L	1.704	1.00
41_E	88_Y	1.684	1.00
174_T	395_K	1.682	1.00
617_T	627_T	1.675	1.00
250_F	347_S	1.675	1.00
44_E	61_E	1.667	1.00
468_T	544_D	1.664	1.00
38_E	68_D	1.661	1.00
41_E	90_P	1.651	1.00
428_I	530_T	1.614	1.00
275_E	279_A	1.612	1.00
203_A	275_E	1.609	1.00
77_L	81_Q	1.609	1.00
575_S	579_E	1.597	1.00
350_Y	354_E	1.596	1.00
464_I	538_P	1.592	1.00
410_V	453_Y	1.592	1.00
24_W	31_V	1.589	1.00
32_N	73_F	1.589	1.00
34_S	69_I	1.589	1.00
24_W	28_D	1.588	1.00
332_T	367_A	1.585	1.00
24_W	79_P	1.584	1.00
431_F	434_G	1.581	1.00
208_I	279_A	1.578	1.00
636_I	640_E	1.562	1.00
221_L	224_V	1.554	1.00
175_V	589_R	1.548	1.00
627_T	630_S	1.539	1.00
476_E	547_S	1.532	1.00
585_I	589_R	1.526	1.00
466_Y	469_S	1.522	1.00
179_V	542_G	1.519	1.00
232_F	236_K	1.516	1.00
269_F	355_M	1.513	1.00
195_I	200_E	1.512	1.00
442_I	663_L	1.506	1.00
532_L	540_I	1.496	1.00
211_L	219_V	1.495	1.00
47_L	81_Q	1.487	1.00
225_F	246_P	1.482	1.00
550_Q	556_A	1.481	1.00
341_I	380_T	1.474	1.00
525_R	576_K	1.470	1.00
633_Q	637_F	1.469	1.00
441_E	444_N	1.463	1.00
176_I	464_I	1.462	1.00
121_D	231_R	1.461	1.00
184_F	210_Y	1.452	1.00
181_V	221_L	1.451	1.00
157_E	274_N	1.447	1.00
34_S	71_H	1.444	1.00
316_Q	320_K	1.444	1.00
188_R	207_M	1.443	1.00
64_N	67_G	1.436	1.00
209_S	213_D	1.434	1.00
521_E	525_R	1.431	1.00
591_H	656_D	1.423	1.00
571_D	578_L	1.418	1.00
257_S	265_Q	1.417	1.00
19_P	34_S	1.413	1.00
66_T	71_H	1.408	1.00
20_L	34_S	1.395	1.00
46_L	86_R	1.385	1.00
381_F	385_L	1.383	1.00
353_T	390_I	1.383	1.00
33_F	45_L	1.382	1.00
384_A	389_P	1.377	1.00
202_L	272_M	1.376	1.00
388_D	391_L	1.375	1.00
421_N	463_S	1.363	1.00
533_V	615_F	1.357	1.00
523_Q	526_N	1.357	1.00
46_L	104_V	1.351	1.00
231_R	235_D	1.351	1.00
266_V	355_M	1.347	1.00
22_S	33_F	1.345	1.00
528_M	577_F	1.343	1.00
666_N	670_V	1.341	1.00
430_R	435_E	1.340	1.00
568_W	571_D	1.339	1.00
272_M	276_L	1.338	1.00
334_N	337_H	1.335	1.00
210_Y	546_L	1.335	1.00
469_S	539_M	1.329	1.00
192_P	195_I	1.325	1.00
220_E	420_W	1.322	1.00
524_K	577_F	1.321	1.00
32_N	71_H	1.321	1.00
257_S	264_G	1.320	1.00
445_R	451_D	1.318	1.00
20_L	69_I	1.310	1.00
516_V	519_C	1.309	1.00
173_D	589_R	1.308	1.00
63_K	72_V	1.306	1.00
187_L	190_D	1.284	1.00
428_I	442_I	1.283	0.99
252_P	351_W	1.277	0.99
267_L	270_K	1.275	0.99
635_V	641_G	1.273	0.99
556_A	563_I	1.270	0.99
160_D	356_H	1.265	0.99
229_D	239_T	1.261	0.99
28_D	73_F	1.259	0.99
200_E	203_A	1.259	0.99
385_L	394_V	1.254	0.99
574_K	577_F	1.253	0.99
624_D	627_T	1.247	0.99
382_F	388_D	1.247	0.99
110_A	120_N	1.245	0.99
209_S	212_K	1.244	0.99
159_D	278_N	1.244	0.99
156_F	274_N	1.243	0.99
348_L	381_F	1.242	0.99
59_I	86_R	1.235	0.99
376_N	379_N	1.229	0.99
349_R	384_A	1.221	0.99
161_E	274_N	1.211	0.99
374_S	377_M	1.207	0.99
156_F	356_H	1.202	0.99
202_L	276_L	1.198	0.99
602_G	612_D	1.194	0.99
365_A	398_A	1.192	0.99
60_I	74_V	1.180	0.99
203_A	271_K	1.174	0.99
352_V	391_L	1.171	0.99
637_F	661_I	1.170	0.99
258_S	268_S	1.168	0.99
226_H	253_E	1.167	0.99
594_F	659_F	1.166	0.99
191_L	207_M	1.166	0.99
78_R	81_Q	1.165	0.99
637_F	641_G	1.165	0.99
601_Q	605_L	1.163	0.99
634_L	640_E	1.163	0.99
113_I	226_H	1.161	0.99
352_V	385_L	1.150	0.99
181_V	224_V	1.147	0.99
282_E	395_K	1.142	0.99
39_N	97_L	1.141	0.99
284_I	397_I	1.136	0.99
629_S	632_T	1.132	0.99
216_I	281_I	1.126	0.99
603_K	606_F	1.125	0.99
36_F	339_R	1.124	0.99
250_F	343_M	1.119	0.99
636_I	641_G	1.115	0.99
325_D	367_A	1.114	0.99
171_L	174_T	1.112	0.99
548_R	566_F	1.111	0.99
571_D	574_K	1.107	0.99
111_K	350_Y	1.107	0.99
105_L	307_I	1.106	0.98
633_Q	636_I	1.105	0.98
156_F	160_D	1.102	0.98
519_C	523_Q	1.101	0.98
250_F	350_Y	1.100	0.98
638_V	641_G	1.100	0.98
38_E	311_A	1.097	0.98
548_R	564_T	1.089	0.98
316_Q	324_L	1.086	0.98
46_L	59_I	1.086	0.98
305_R	309_N	1.084	0.98
16_D	19_P	1.082	0.98
15_G	32_N	1.080	0.98
227_F	230_Q	1.080	0.98
656_D	659_F	1.078	0.98
371_E	380_T	1.078	0.98
521_E	574_K	1.075	0.98
157_E	356_H	1.074	0.98
161_E	277_H	1.074	0.98
156_F	270_K	1.073	0.98
325_D	328_G	1.073	0.98
421_N	465_N	1.071	0.98
584_M	683_I	1.071	0.98
611_K	622_E	1.071	0.98
604_K	607_G	1.070	0.98
635_V	640_E	1.069	0.98
192_P	196_R	1.067	0.98
185_T	201_G	1.066	0.98
612_D	615_F	1.062	0.98
579_E	583_K	1.060	0.98
348_L	362_F	1.058	0.98
65_K	68_D	1.056	0.98
580_F	584_M	1.051	0.98
623_V	627_T	1.049	0.98
553_N	559_Q	1.049	0.98
15_G	18_Y	1.049	0.98
39_N	308_D	1.045	0.98
626_K	629_S	1.042	0.98
15_G	19_P	1.041	0.98
31_V	78_R	1.039	0.98
37_S	308_D	1.036	0.98
36_F	311_A	1.035	0.98
439_Y	442_I	1.034	0.98
274_N	278_N	1.032	0.98
179_V	207_M	1.031	0.98
556_A	564_T	1.030	0.98
227_F	256_Y	1.030	0.98
591_H	659_F	1.025	0.98
423_K	441_E	1.019	0.97
184_F	211_L	1.017	0.97
90_P	96_G	1.016	0.97
301_T	305_R	1.015	0.97
440_S	443_A	1.014	0.97
274_N	356_H	1.009	0.97
276_L	281_I	1.006	0.97
511_T	517_V	1.002	0.97
86_R	104_V	1.000	0.97
653_R	656_D	0.996	0.97
306_G	309_N	0.995	0.97
202_L	219_V	0.995	0.97
420_W	539_M	0.992	0.97
634_L	638_V	0.992	0.97
615_F	628_W	0.988	0.97
521_E	576_K	0.987	0.97
625_E	629_S	0.987	0.97
305_R	310_T	0.986	0.97
602_G	605_L	0.986	0.97
158_W	274_N	0.985	0.97
444_N	450_P	0.985	0.97
349_R	353_T	0.985	0.97
157_E	160_D	0.983	0.97
185_T	207_M	0.979	0.97
409_Q	413_F	0.979	0.97
202_L	221_L	0.977	0.97
191_L	206_Q	0.976	0.97
225_F	285_I	0.974	0.97
89_G	103_K	0.974	0.97
333_L	343_M	0.973	0.97
190_D	193_E	0.972	0.97
185_T	197_G	0.971	0.97
380_T	383_I	0.971	0.97
444_N	451_D	0.966	0.96
567_D	571_D	0.966	0.96
369_A	375_V	0.964	0.96
208_I	276_L	0.961	0.96
525_R	577_F	0.960	0.96
208_I	275_E	0.958	0.96
446_L	534_S	0.957	0.96
311_A	337_H	0.955	0.96
681_L	684_S	0.954	0.96
88_Y	101_P	0.947	0.96
344_V	368_L	0.946	0.96
442_I	445_R	0.943	0.96
264_G	267_L	0.939	0.96
45_L	72_V	0.937	0.96
345_L	381_F	0.935	0.96
327_T	367_A	0.935	0.96
598_R	601_Q	0.934	0.96
651_G	654_I	0.932	0.96
19_P	23_N	0.932	0.96
180_H	222_M	0.931	0.96
208_I	212_K	0.930	0.96
23_N	32_N	0.930	0.96
565_W	568_W	0.928	0.96
546_L	571_D	0.928	0.96
224_V	285_I	0.927	0.96
441_E	445_R	0.926	0.95
406_G	409_Q	0.926	0.95
37_S	40_A	0.925	0.95
39_N	310_T	0.921	0.95
217_T	281_I	0.921	0.95
442_I	446_L	0.921	0.95
218_T	282_E	0.918	0.95
229_D	245_D	0.915	0.95
582_K	585_I	0.915	0.95
447_L	450_P	0.914	0.95
316_Q	319_N	0.911	0.95
638_V	642_S	0.911	0.95
153_N	156_F	0.911	0.95
600_F	604_K	0.911	0.95
267_L	271_K	0.911	0.95
410_V	413_F	0.911	0.95
578_L	581_V	0.910	0.95
98_R	301_T	0.908	0.95
373_Y	377_M	0.904	0.95
187_L	562_E	0.900	0.95
617_T	621_R	0.898	0.95
380_T	384_A	0.894	0.95
541_L	548_R	0.892	0.94
432_W	530_T	0.892	0.94
49_S	53_Q	0.889	0.94
229_D	255_R	0.887	0.94
195_I	201_G	0.887	0.94
684_S	687_L	0.886	0.94
247_I	293_A	0.886	0.94
418_A	537_T	0.886	0.94
687_L	690_I	0.885	0.94
156_F	159_D	0.883	0.94
407_G	411_G	0.883	0.94
181_V	202_L	0.879	0.94
109_Y	346_D	0.878	0.94
656_D	662_I	0.875	0.94
214_L	585_I	0.875	0.94
304_F	307_I	0.872	0.94
636_I	639_L	0.870	0.94
467_V	527_F	0.870	0.94
45_L	85_Y	0.870	0.94
547_S	574_K	0.870	0.94
37_S	68_D	0.864	0.93
160_D	274_N	0.864	0.93
287_V	348_L	0.859	0.93
50_L	53_Q	0.855	0.93
154_P	158_W	0.855	0.93
171_L	418_A	0.854	0.93
546_L	578_L	0.853	0.93
228_I	247_I	0.853	0.93
191_L	195_I	0.849	0.93
161_E	165_K	0.849	0.93
254_C	265_Q	0.849	0.93
187_L	191_L	0.849	0.93
529_I	584_M	0.844	0.93
371_E	383_I	0.843	0.93
210_Y	578_L	0.840	0.93
601_Q	604_K	0.839	0.92
525_R	580_F	0.838	0.92
184_F	219_V	0.836	0.92
292_T	333_L	0.834	0.92
246_P	249_F	0.832	0.92
373_Y	379_N	0.831	0.92
430_R	438_P	0.830	0.92
315_L	323_Y	0.829	0.92
528_M	544_D	0.827	0.92
633_Q	641_G	0.827	0.92
125_G	301_T	0.825	0.92
149_S	152_I	0.824	0.92
179_V	221_L	0.823	0.92
227_F	253_E	0.822	0.92
549_T	570_L	0.821	0.92
253_E	256_Y	0.821	0.92
637_F	642_S	0.820	0.92
344_V	381_F	0.818	0.91
540_I	581_V	0.817	0.91
218_T	281_I	0.816	0.91
559_Q	563_I	0.815	0.91
583_K	586_Q	0.815	0.91
375_V	378_L	0.814	0.91
249_F	343_M	0.814	0.91
363_D	471_D	0.814	0.91
624_D	630_S	0.813	0.91
297_H	325_D	0.812	0.91
440_S	444_N	0.810	0.91
270_K	350_Y	0.808	0.91
49_S	52_N	0.806	0.91
660_L	663_L	0.803	0.91
408_Y	411_G	0.802	0.91
182_K	561_N	0.801	0.91
587_F	591_H	0.800	0.91
474_T	548_R	0.800	0.91
48_Y	104_V	0.800	0.91
225_F	347_S	0.799	0.91
19_P	32_N	0.797	0.90
201_G	272_M	0.795	0.90
199_Y	252_P	0.795	0.90
409_Q	414_P	0.793	0.90
656_D	660_L	0.792	0.90
349_R	390_I	0.792	0.90
79_P	152_I	0.792	0.90
259_T	264_G	0.791	0.90
594_F	639_L	0.791	0.90
521_E	577_F	0.790	0.90
219_V	281_I	0.790	0.90
613_V	616_Y	0.789	0.90
157_E	161_E	0.788	0.90
304_F	309_N	0.787	0.90
64_N	71_H	0.786	0.90
119_W	231_R	0.786	0.90
515_N	519_C	0.786	0.90
576_K	579_E	0.786	0.90
431_F	665_A	0.784	0.90
211_L	216_I	0.783	0.90
529_I	533_V	0.783	0.90
622_E	627_T	0.782	0.90
635_V	638_V	0.782	0.90
13_R	16_D	0.780	0.89
270_K	356_H	0.777	0.89
192_P	206_Q	0.776	0.89
252_P	269_F	0.775	0.89
27_D	30_G	0.775	0.89
661_I	665_A	0.773	0.89
476_E	549_T	0.772	0.89
46_L	84_A	0.772	0.89
634_L	672_V	0.771	0.89
113_I	251_S	0.771	0.89
95_L	101_P	0.771	0.89
683_I	688_R	0.770	0.89
399_E	470_H	0.769	0.89
410_V	414_P	0.769	0.89
188_R	191_L	0.768	0.89
170_P	173_D	0.768	0.89
154_P	270_K	0.767	0.89
370_R	379_N	0.763	0.88
227_F	246_P	0.761	0.88
582_K	586_Q	0.760	0.88
624_D	629_S	0.760	0.88
229_D	240_N	0.760	0.88
688_R	691_K	0.759	0.88
36_F	337_H	0.758	0.88
106_I	248_N	0.757	0.88
111_K	354_E	0.756	0.88
195_I	198_T	0.752	0.88
245_D	293_A	0.749	0.87
636_I	662_I	0.747	0.87
271_K	274_N	0.746	0.87
259_T	265_Q	0.743	0.87
211_L	281_I	0.743	0.87
510_P	551_R	0.743	0.87
250_F	289_Y	0.742	0.87
43_V	85_Y	0.742	0.87
269_F	285_I	0.741	0.87
361_R	471_D	0.741	0.87
285_I	357_V	0.740	0.87
191_L	201_G	0.737	0.87
90_P	97_L	0.736	0.87
304_F	340_V	0.736	0.87
634_L	664_N	0.732	0.86
154_P	159_D	0.732	0.86
76_G	79_P	0.731	0.86
572_E	575_S	0.731	0.86
171_L	395_K	0.731	0.86
159_D	356_H	0.730	0.86
384_A	391_L	0.730	0.86
158_W	270_K	0.729	0.86
268_S	271_K	0.729	0.86
587_F	682_V	0.724	0.86
341_I	383_I	0.724	0.86
601_Q	606_F	0.723	0.86
199_Y	272_M	0.722	0.86
62_V	85_Y	0.721	0.85
627_T	631_P	0.721	0.85
282_E	391_L	0.720	0.85
43_V	70_W	0.719	0.85
401_W	425_R	0.719	0.85
179_V	211_L	0.719	0.85
168_K	393_Q	0.716	0.85
208_I	281_I	0.716	0.85
40_A	308_D	0.715	0.85
195_I	206_Q	0.714	0.85
575_S	578_L	0.714	0.85
430_R	433_R	0.713	0.85
684_S	688_R	0.713	0.85
531_L	534_S	0.712	0.85
363_D	399_E	0.711	0.85
290_N	364_L	0.710	0.85
187_L	192_P	0.708	0.84
446_L	613_V	0.707	0.84
362_F	396_L	0.707	0.84
411_G	414_P	0.707	0.84
332_T	405_Q	0.706	0.84
307_I	311_A	0.705	0.84
635_V	639_L	0.705	0.84
341_I	345_L	0.704	0.84
316_Q	325_D	0.704	0.84
634_L	670_V	0.704	0.84
166_G	356_H	0.702	0.84
333_L	368_L	0.702	0.84
116_S	253_E	0.702	0.84
422_G	453_Y	0.699	0.84
524_K	528_M	0.699	0.84
623_V	628_W	0.698	0.84
37_S	311_A	0.698	0.84
108_P	307_I	0.693	0.83
151_V	154_P	0.691	0.83
182_K	560_D	0.690	0.83
468_T	478_L	0.690	0.83
277_H	283_V	0.690	0.83
45_L	74_V	0.689	0.83
222_M	542_G	0.688	0.83
184_F	276_L	0.688	0.83
567_D	573_R	0.688	0.83
22_S	85_Y	0.687	0.83
156_F	161_E	0.686	0.82
518_I	522_K	0.686	0.82
634_L	641_G	0.685	0.82
378_L	417_W	0.683	0.82
326_F	329_T	0.682	0.82
258_S	264_G	0.680	0.82
523_Q	527_F	0.680	0.82
602_G	606_F	0.680	0.82
24_W	29_D	0.680	0.82
611_K	614_T	0.679	0.82
349_R	388_D	0.678	0.82
424_Y	427_S	0.677	0.82
627_T	632_T	0.676	0.82
326_F	405_Q	0.676	0.82
399_E	471_D	0.675	0.81
118_I	247_I	0.675	0.81
189_L	196_R	0.674	0.81
236_K	558_C	0.673	0.81
207_M	211_L	0.672	0.81
352_V	360_F	0.672	0.81
542_G	548_R	0.672	0.81
220_E	397_I	0.670	0.81
375_V	379_N	0.670	0.81
229_D	253_E	0.670	0.81
428_I	467_V	0.670	0.81
596_R	599_Y	0.669	0.81
469_S	541_L	0.669	0.81
583_K	683_I	0.668	0.81
74_V	81_Q	0.668	0.81
79_P	125_G	0.668	0.81
73_F	79_P	0.667	0.81
391_L	394_V	0.665	0.81
434_G	442_I	0.663	0.80
249_F	329_T	0.661	0.80
309_N	323_Y	0.661	0.80
51_T	54_K	0.661	0.80
603_K	607_G	0.660	0.80
220_E	539_M	0.660	0.80
620_G	623_V	0.659	0.80
226_H	265_Q	0.659	0.80
307_I	310_T	0.657	0.80
214_L	578_L	0.657	0.80
178_E	242_W	0.657	0.80
203_A	272_M	0.655	0.80
395_K	418_A	0.655	0.80
361_R	399_E	0.653	0.79
199_Y	224_V	0.652	0.79
231_R	234_T	0.651	0.79
407_G	413_F	0.651	0.79
232_F	245_D	0.651	0.79
564_T	568_W	0.651	0.79
517_V	521_E	0.650	0.79
45_L	62_V	0.650	0.79
546_L	570_L	0.650	0.79
212_K	589_R	0.649	0.79
559_Q	564_T	0.647	0.79
621_R	624_D	0.645	0.78
560_D	565_W	0.644	0.78
444_N	447_L	0.644	0.78
225_F	293_A	0.644	0.78
326_F	374_S	0.642	0.78
599_Y	603_K	0.642	0.78
544_D	581_V	0.641	0.78
221_L	272_M	0.641	0.78
418_A	461_F	0.640	0.78
600_F	603_K	0.639	0.78
249_F	347_S	0.637	0.78
515_N	518_I	0.636	0.77
681_L	688_R	0.636	0.77
85_Y	109_Y	0.635	0.77
408_Y	413_F	0.635	0.77
639_L	642_S	0.635	0.77
175_V	217_T	0.634	0.77
109_Y	312_Y	0.632	0.77
36_F	68_D	0.632	0.77
195_I	258_S	0.632	0.77
674_F	679_W	0.631	0.77
252_P	350_Y	0.629	0.77
388_D	417_W	0.629	0.77
105_L	108_P	0.627	0.77
184_F	568_W	0.627	0.77
272_M	355_M	0.626	0.76
681_L	690_I	0.626	0.76
679_W	684_S	0.625	0.76
232_F	235_D	0.625	0.76
599_Y	604_K	0.625	0.76
448_G	451_D	0.624	0.76
458_K	462_A	0.623	0.76
681_L	691_K	0.621	0.76
326_F	332_T	0.621	0.76
263_G	266_V	0.620	0.76
35_L	85_Y	0.619	0.76
468_T	541_L	0.618	0.75
467_V	531_L	0.618	0.75
366_A	398_A	0.616	0.75
38_E	337_H	0.616	0.75
39_N	311_A	0.615	0.75
13_R	75_P	0.615	0.75
634_L	639_L	0.615	0.75
613_V	637_F	0.613	0.75
88_Y	102_N	0.613	0.75
615_F	618_L	0.613	0.75
33_F	74_V	0.612	0.75
31_V	79_P	0.612	0.75
314_M	324_L	0.612	0.75
206_Q	210_Y	0.611	0.75
37_S	43_V	0.610	0.75
310_T	315_L	0.608	0.74
407_G	412_N	0.608	0.74
519_C	522_K	0.608	0.74
638_V	660_L	0.607	0.74
213_D	571_D	0.606	0.74
299_G	304_F	0.605	0.74
114_N	122_A	0.604	0.74
438_P	441_E	0.604	0.74
341_I	381_F	0.604	0.74
153_N	160_D	0.604	0.74
613_V	628_W	0.604	0.74
433_R	523_Q	0.603	0.74
594_F	663_L	0.603	0.74
385_L	391_L	0.603	0.74
65_K	71_H	0.603	0.74
185_T	188_R	0.602	0.74
569_N	573_R	0.600	0.73
659_F	663_L	0.599	0.73
446_L	533_V	0.599	0.73
579_E	690_I	0.599	0.73
538_P	588_Y	0.598	0.73
240_N	245_D	0.598	0.73
659_F	682_V	0.596	0.73
553_N	558_C	0.596	0.73
365_A	417_W	0.596	0.73
521_E	547_S	0.595	0.73
172_K	459_T	0.595	0.73
424_Y	531_L	0.594	0.73
305_R	311_A	0.591	0.72
23_N	34_S	0.590	0.72
535_Q	594_F	0.590	0.72
397_I	539_M	0.590	0.72
165_K	168_K	0.590	0.72
155_Y	160_D	0.590	0.72
616_Y	619_E	0.590	0.72
272_M	275_E	0.589	0.72
180_H	241_Y	0.589	0.72
638_V	658_S	0.589	0.72
577_F	581_V	0.589	0.72
596_R	601_Q	0.588	0.72
684_S	690_I	0.588	0.72
208_I	211_L	0.588	0.72
49_S	81_Q	0.587	0.72
54_K	58_E	0.586	0.72
174_T	282_E	0.586	0.72
249_F	333_L	0.586	0.72
632_T	635_V	0.585	0.71
407_G	410_V	0.585	0.71
663_L	666_N	0.584	0.71
246_P	293_A	0.584	0.71
255_R	265_Q	0.583	0.71
588_Y	595_R	0.583	0.71
596_R	602_G	0.582	0.71
309_N	315_L	0.582	0.71
632_T	637_F	0.582	0.71
616_Y	623_V	0.582	0.71
166_G	282_E	0.582	0.71
109_Y	342_Q	0.581	0.71
439_Y	447_L	0.580	0.71
306_G	310_T	0.580	0.71
230_Q	245_D	0.580	0.71
535_Q	596_R	0.579	0.71
291_H	471_D	0.579	0.71
561_N	564_T	0.578	0.71
230_Q	329_T	0.578	0.71
61_E	70_W	0.578	0.71
540_I	544_D	0.578	0.71
482_N	485_H	0.577	0.70
258_S	265_Q	0.577	0.70
107_D	110_A	0.576	0.70
447_L	451_D	0.574	0.70
284_I	359_G	0.574	0.70
83_Y	107_D	0.573	0.70
424_Y	428_I	0.573	0.70
570_L	573_R	0.573	0.70
466_Y	484_K	0.572	0.70
581_V	587_F	0.572	0.70
560_D	564_T	0.571	0.70
615_F	619_E	0.571	0.70
422_G	425_R	0.570	0.69
179_V	566_F	0.570	0.69
340_V	343_M	0.569	0.69
636_I	642_S	0.569	0.69
633_Q	640_E	0.568	0.69
230_Q	233_L	0.568	0.69
479_V	523_Q	0.568	0.69
371_E	376_N	0.567	0.69
167_K	274_N	0.567	0.69
559_Q	565_W	0.567	0.69
533_V	584_M	0.566	0.69
348_L	385_L	0.565	0.69
53_Q	58_E	0.565	0.69
29_D	76_G	0.565	0.69
153_N	158_W	0.565	0.69
191_L	194_N	0.565	0.69
466_Y	539_M	0.564	0.69
182_K	199_Y	0.564	0.69
345_L	384_A	0.564	0.69
556_A	559_Q	0.564	0.69
341_I	372_L	0.563	0.69
425_R	429_R	0.563	0.69
112_A	265_Q	0.562	0.68
197_G	201_G	0.561	0.68
591_H	595_R	0.561	0.68
683_I	686_Y	0.561	0.68
17_P	34_S	0.559	0.68
422_G	466_Y	0.556	0.68
630_S	633_Q	0.556	0.68
511_T	516_V	0.555	0.67
433_R	437_L	0.555	0.67
652_E	656_D	0.555	0.67
157_E	270_K	0.555	0.67
403_V	406_G	0.554	0.67
74_V	78_R	0.554	0.67
599_Y	605_L	0.553	0.67
623_V	626_K	0.553	0.67
407_G	414_P	0.553	0.67
388_D	396_L	0.553	0.67
558_C	564_T	0.553	0.67
41_E	89_G	0.553	0.67
187_L	193_E	0.552	0.67
510_P	513_D	0.552	0.67
315_L	320_K	0.552	0.67
662_I	674_F	0.552	0.67
219_V	283_V	0.551	0.67
652_E	655_A	0.551	0.67
257_S	268_S	0.550	0.67
446_L	637_F	0.549	0.67
587_F	594_F	0.548	0.67
522_K	526_N	0.547	0.66
635_V	642_S	0.547	0.66
116_S	229_D	0.546	0.66
54_K	86_R	0.546	0.66
427_S	438_P	0.545	0.66
480_S	520_R	0.545	0.66
172_K	597_E	0.544	0.66
602_G	607_G	0.543	0.66
225_F	228_I	0.543	0.66
308_D	311_A	0.542	0.66
431_F	435_E	0.541	0.66
311_A	314_M	0.541	0.66
106_I	149_S	0.541	0.66
233_L	236_K	0.540	0.65
374_S	379_N	0.539	0.65
555_N	558_C	0.539	0.65
630_S	634_L	0.539	0.65
565_W	571_D	0.538	0.65
431_F	442_I	0.538	0.65
244_Y	399_E	0.537	0.65
446_L	530_T	0.537	0.65
659_F	665_A	0.537	0.65
329_T	558_C	0.537	0.65
228_I	293_A	0.536	0.65
87_V	105_L	0.535	0.65
528_M	532_L	0.534	0.65
510_P	517_V	0.534	0.65
283_V	358_D	0.534	0.65
550_Q	564_T	0.533	0.64
67_G	416_Q	0.532	0.64
68_D	339_R	0.532	0.64
514_Q	518_I	0.532	0.64
687_L	691_K	0.531	0.64
149_S	303_S	0.531	0.64
581_V	584_M	0.530	0.64
678_K	691_K	0.530	0.64
198_T	258_S	0.530	0.64
333_L	365_A	0.530	0.64
620_G	628_W	0.529	0.64
559_Q	568_W	0.529	0.64
559_Q	562_E	0.528	0.64
332_T	406_G	0.528	0.64
115_G	233_L	0.528	0.64
33_F	83_Y	0.528	0.64
286_D	399_E	0.527	0.64
210_Y	213_D	0.527	0.64
238_L	558_C	0.527	0.64
473_F	554_N	0.525	0.63
533_V	661_I	0.525	0.63
657_D	666_N	0.525	0.63
325_D	329_T	0.525	0.63
116_S	231_R	0.524	0.63
389_P	392_S	0.522	0.63
187_L	567_D	0.522	0.63
167_K	273_V	0.522	0.63
120_N	123_V	0.521	0.63
670_V	673_K	0.519	0.62
668_N	676_K	0.519	0.62
637_F	663_L	0.519	0.62
594_F	602_G	0.518	0.62
155_Y	267_L	0.518	0.62
657_D	662_I	0.517	0.62
563_I	568_W	0.516	0.62
304_F	333_L	0.516	0.62
150_V	153_N	0.515	0.62
542_G	546_L	0.515	0.62
432_W	527_F	0.513	0.61
409_Q	415_Y	0.512	0.61
48_Y	84_A	0.512	0.61
177_Y	214_L	0.512	0.61
373_Y	405_Q	0.511	0.61
286_D	361_R	0.511	0.61
373_Y	378_L	0.508	0.61
678_K	688_R	0.508	0.61
335_L	368_L	0.508	0.61
116_S	254_C	0.508	0.61
633_Q	665_A	0.507	0.61
190_D	206_Q	0.507	0.61
677_G	686_Y	0.507	0.61
651_G	659_F	0.507	0.61
161_E	166_G	0.506	0.60
439_Y	443_A	0.506	0.60
22_S	30_G	0.506	0.60
244_Y	470_H	0.505	0.60
15_G	71_H	0.503	0.60
476_E	521_E	0.503	0.60
367_A	403_V	0.503	0.60
435_E	438_P	0.502	0.60
447_L	613_V	0.501	0.60
291_H	363_D	0.501	0.60
370_R	553_N	0.500	0.60
314_M	334_N	0.500	0.60
201_G	276_L	0.500	0.60

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
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HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2vr5A	5	0.9958	100	0.22	Contact Map
4j7rA	2	0.9471	100	0.25	Contact Map
1bf2A	1	0.9276	100	0.26	Contact Map
2wskA	1	0.9109	100	0.289	Contact Map
4j3vA	1	0.8733	100	0.333	Contact Map
2wanA	1	0.8287	100	0.34	Contact Map
3wdhA	1	0.8148	100	0.343	Contact Map
2e8yA	1	0.8245	100	0.347	Contact Map
2fhfA	1	0.8663	100	0.354	Contact Map
3fawA	1	0.8607	100	0.377	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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