GREMLIN Database
Q7LX99 - Glycogen debranching enzyme (TreX)
UniProt: Q7LX99 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 718 (598)
Sequences: 4359 (2850)
Seq/√Len: 116.5

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
213_D582_K4.0071.00
35_L307_I3.8321.00
269_F273_V3.6211.00
179_V184_F3.5871.00
161_E356_H3.5191.00
158_W356_H3.5171.00
62_V72_V3.4651.00
289_Y347_S3.3851.00
352_V394_V3.2091.00
200_E271_K3.1341.00
275_E278_N3.0221.00
350_Y355_M2.9541.00
43_V87_V2.8231.00
27_D73_F2.7961.00
30_G73_F2.7761.00
87_V307_I2.7731.00
35_L43_V2.7551.00
42_K61_E2.7391.00
586_Q590_A2.6801.00
212_K279_A2.6251.00
547_S577_F2.6011.00
82_L114_N2.5211.00
44_E88_Y2.5011.00
33_F85_Y2.4961.00
174_T218_T2.4841.00
219_V276_L2.4641.00
224_V269_F2.4641.00
35_L87_V2.4371.00
169_V218_T2.4261.00
528_M581_V2.4021.00
476_E524_K2.3941.00
200_E268_S2.3891.00
184_F207_M2.3661.00
218_T284_I2.3541.00
213_D578_L2.3461.00
173_D595_R2.3451.00
182_K186_K2.3431.00
424_Y534_S2.3311.00
542_G566_F2.3051.00
156_F271_K2.2481.00
570_L574_K2.2321.00
269_F272_M2.2111.00
567_D570_L2.2031.00
532_L585_I2.2001.00
22_S31_V2.1911.00
427_S441_E2.1471.00
339_R342_Q2.1181.00
634_L637_F2.1131.00
333_L340_V2.1071.00
271_K275_E2.0811.00
209_S279_A2.0771.00
270_K354_E2.0741.00
304_F343_M2.0551.00
159_D274_N2.0421.00
47_L60_I2.0401.00
74_V77_L2.0371.00
277_H358_D2.0281.00
175_V585_I2.0281.00
199_Y257_S2.0271.00
524_K547_S2.0171.00
662_I672_V2.0161.00
528_M540_I2.0061.00
193_E196_R1.9991.00
191_L196_R1.9851.00
174_T217_T1.9651.00
476_E510_P1.9351.00
546_L566_F1.9321.00
578_L582_K1.9241.00
579_E582_K1.9111.00
292_T313_Y1.9051.00
97_L310_T1.9011.00
373_Y376_N1.8841.00
521_E524_K1.8631.00
60_I72_V1.8621.00
113_I248_N1.8521.00
476_E480_S1.8411.00
106_I113_I1.8391.00
551_R563_I1.8371.00
31_V77_L1.8131.00
269_F357_V1.8121.00
226_H254_C1.8101.00
44_E86_R1.8061.00
84_A104_V1.8021.00
409_Q412_N1.7801.00
183_G241_Y1.7781.00
637_F640_E1.7711.00
42_K88_Y1.7641.00
248_N251_S1.7601.00
335_L344_V1.7601.00
179_V202_L1.7591.00
44_E59_I1.7371.00
179_V219_V1.7331.00
528_M584_M1.7311.00
342_Q346_D1.7301.00
158_W161_E1.7091.00
43_V307_I1.7051.00
184_F202_L1.7041.00
41_E88_Y1.6841.00
174_T395_K1.6821.00
617_T627_T1.6751.00
250_F347_S1.6751.00
44_E61_E1.6671.00
468_T544_D1.6641.00
38_E68_D1.6611.00
41_E90_P1.6511.00
428_I530_T1.6141.00
275_E279_A1.6121.00
203_A275_E1.6091.00
77_L81_Q1.6091.00
575_S579_E1.5971.00
350_Y354_E1.5961.00
464_I538_P1.5921.00
410_V453_Y1.5921.00
24_W31_V1.5891.00
32_N73_F1.5891.00
34_S69_I1.5891.00
24_W28_D1.5881.00
332_T367_A1.5851.00
24_W79_P1.5841.00
431_F434_G1.5811.00
208_I279_A1.5781.00
636_I640_E1.5621.00
221_L224_V1.5541.00
175_V589_R1.5481.00
627_T630_S1.5391.00
476_E547_S1.5321.00
585_I589_R1.5261.00
466_Y469_S1.5221.00
179_V542_G1.5191.00
232_F236_K1.5161.00
269_F355_M1.5131.00
195_I200_E1.5121.00
442_I663_L1.5061.00
532_L540_I1.4961.00
211_L219_V1.4951.00
47_L81_Q1.4871.00
225_F246_P1.4821.00
550_Q556_A1.4811.00
341_I380_T1.4741.00
525_R576_K1.4701.00
633_Q637_F1.4691.00
441_E444_N1.4631.00
176_I464_I1.4621.00
121_D231_R1.4611.00
184_F210_Y1.4521.00
181_V221_L1.4511.00
157_E274_N1.4471.00
34_S71_H1.4441.00
316_Q320_K1.4441.00
188_R207_M1.4431.00
64_N67_G1.4361.00
209_S213_D1.4341.00
521_E525_R1.4311.00
591_H656_D1.4231.00
571_D578_L1.4181.00
257_S265_Q1.4171.00
19_P34_S1.4131.00
66_T71_H1.4081.00
20_L34_S1.3951.00
46_L86_R1.3851.00
381_F385_L1.3831.00
353_T390_I1.3831.00
33_F45_L1.3821.00
384_A389_P1.3771.00
202_L272_M1.3761.00
388_D391_L1.3751.00
421_N463_S1.3631.00
533_V615_F1.3571.00
523_Q526_N1.3571.00
46_L104_V1.3511.00
231_R235_D1.3511.00
266_V355_M1.3471.00
22_S33_F1.3451.00
528_M577_F1.3431.00
666_N670_V1.3411.00
430_R435_E1.3401.00
568_W571_D1.3391.00
272_M276_L1.3381.00
334_N337_H1.3351.00
210_Y546_L1.3351.00
469_S539_M1.3291.00
192_P195_I1.3251.00
220_E420_W1.3221.00
524_K577_F1.3211.00
32_N71_H1.3211.00
257_S264_G1.3201.00
445_R451_D1.3181.00
20_L69_I1.3101.00
516_V519_C1.3091.00
173_D589_R1.3081.00
63_K72_V1.3061.00
187_L190_D1.2841.00
428_I442_I1.2830.99
252_P351_W1.2770.99
267_L270_K1.2750.99
635_V641_G1.2730.99
556_A563_I1.2700.99
160_D356_H1.2650.99
229_D239_T1.2610.99
28_D73_F1.2590.99
200_E203_A1.2590.99
385_L394_V1.2540.99
574_K577_F1.2530.99
624_D627_T1.2470.99
382_F388_D1.2470.99
110_A120_N1.2450.99
209_S212_K1.2440.99
159_D278_N1.2440.99
156_F274_N1.2430.99
348_L381_F1.2420.99
59_I86_R1.2350.99
376_N379_N1.2290.99
349_R384_A1.2210.99
161_E274_N1.2110.99
374_S377_M1.2070.99
156_F356_H1.2020.99
202_L276_L1.1980.99
602_G612_D1.1940.99
365_A398_A1.1920.99
60_I74_V1.1800.99
203_A271_K1.1740.99
352_V391_L1.1710.99
637_F661_I1.1700.99
258_S268_S1.1680.99
226_H253_E1.1670.99
594_F659_F1.1660.99
191_L207_M1.1660.99
78_R81_Q1.1650.99
637_F641_G1.1650.99
601_Q605_L1.1630.99
634_L640_E1.1630.99
113_I226_H1.1610.99
352_V385_L1.1500.99
181_V224_V1.1470.99
282_E395_K1.1420.99
39_N97_L1.1410.99
284_I397_I1.1360.99
629_S632_T1.1320.99
216_I281_I1.1260.99
603_K606_F1.1250.99
36_F339_R1.1240.99
250_F343_M1.1190.99
636_I641_G1.1150.99
325_D367_A1.1140.99
171_L174_T1.1120.99
548_R566_F1.1110.99
571_D574_K1.1070.99
111_K350_Y1.1070.99
105_L307_I1.1060.98
633_Q636_I1.1050.98
156_F160_D1.1020.98
519_C523_Q1.1010.98
250_F350_Y1.1000.98
638_V641_G1.1000.98
38_E311_A1.0970.98
548_R564_T1.0890.98
316_Q324_L1.0860.98
46_L59_I1.0860.98
305_R309_N1.0840.98
16_D19_P1.0820.98
15_G32_N1.0800.98
227_F230_Q1.0800.98
656_D659_F1.0780.98
371_E380_T1.0780.98
521_E574_K1.0750.98
157_E356_H1.0740.98
161_E277_H1.0740.98
156_F270_K1.0730.98
325_D328_G1.0730.98
421_N465_N1.0710.98
584_M683_I1.0710.98
611_K622_E1.0710.98
604_K607_G1.0700.98
635_V640_E1.0690.98
192_P196_R1.0670.98
185_T201_G1.0660.98
612_D615_F1.0620.98
579_E583_K1.0600.98
348_L362_F1.0580.98
65_K68_D1.0560.98
580_F584_M1.0510.98
623_V627_T1.0490.98
553_N559_Q1.0490.98
15_G18_Y1.0490.98
39_N308_D1.0450.98
626_K629_S1.0420.98
15_G19_P1.0410.98
31_V78_R1.0390.98
37_S308_D1.0360.98
36_F311_A1.0350.98
439_Y442_I1.0340.98
274_N278_N1.0320.98
179_V207_M1.0310.98
556_A564_T1.0300.98
227_F256_Y1.0300.98
591_H659_F1.0250.98
423_K441_E1.0190.97
184_F211_L1.0170.97
90_P96_G1.0160.97
301_T305_R1.0150.97
440_S443_A1.0140.97
274_N356_H1.0090.97
276_L281_I1.0060.97
511_T517_V1.0020.97
86_R104_V1.0000.97
653_R656_D0.9960.97
306_G309_N0.9950.97
202_L219_V0.9950.97
420_W539_M0.9920.97
634_L638_V0.9920.97
615_F628_W0.9880.97
521_E576_K0.9870.97
625_E629_S0.9870.97
305_R310_T0.9860.97
602_G605_L0.9860.97
158_W274_N0.9850.97
444_N450_P0.9850.97
349_R353_T0.9850.97
157_E160_D0.9830.97
185_T207_M0.9790.97
409_Q413_F0.9790.97
202_L221_L0.9770.97
191_L206_Q0.9760.97
225_F285_I0.9740.97
89_G103_K0.9740.97
333_L343_M0.9730.97
190_D193_E0.9720.97
185_T197_G0.9710.97
380_T383_I0.9710.97
444_N451_D0.9660.96
567_D571_D0.9660.96
369_A375_V0.9640.96
208_I276_L0.9610.96
525_R577_F0.9600.96
208_I275_E0.9580.96
446_L534_S0.9570.96
311_A337_H0.9550.96
681_L684_S0.9540.96
88_Y101_P0.9470.96
344_V368_L0.9460.96
442_I445_R0.9430.96
264_G267_L0.9390.96
45_L72_V0.9370.96
345_L381_F0.9350.96
327_T367_A0.9350.96
598_R601_Q0.9340.96
651_G654_I0.9320.96
19_P23_N0.9320.96
180_H222_M0.9310.96
208_I212_K0.9300.96
23_N32_N0.9300.96
565_W568_W0.9280.96
546_L571_D0.9280.96
224_V285_I0.9270.96
441_E445_R0.9260.95
406_G409_Q0.9260.95
37_S40_A0.9250.95
39_N310_T0.9210.95
217_T281_I0.9210.95
442_I446_L0.9210.95
218_T282_E0.9180.95
229_D245_D0.9150.95
582_K585_I0.9150.95
447_L450_P0.9140.95
316_Q319_N0.9110.95
638_V642_S0.9110.95
153_N156_F0.9110.95
600_F604_K0.9110.95
267_L271_K0.9110.95
410_V413_F0.9110.95
578_L581_V0.9100.95
98_R301_T0.9080.95
373_Y377_M0.9040.95
187_L562_E0.9000.95
617_T621_R0.8980.95
380_T384_A0.8940.95
541_L548_R0.8920.94
432_W530_T0.8920.94
49_S53_Q0.8890.94
229_D255_R0.8870.94
195_I201_G0.8870.94
684_S687_L0.8860.94
247_I293_A0.8860.94
418_A537_T0.8860.94
687_L690_I0.8850.94
156_F159_D0.8830.94
407_G411_G0.8830.94
181_V202_L0.8790.94
109_Y346_D0.8780.94
656_D662_I0.8750.94
214_L585_I0.8750.94
304_F307_I0.8720.94
636_I639_L0.8700.94
467_V527_F0.8700.94
45_L85_Y0.8700.94
547_S574_K0.8700.94
37_S68_D0.8640.93
160_D274_N0.8640.93
287_V348_L0.8590.93
50_L53_Q0.8550.93
154_P158_W0.8550.93
171_L418_A0.8540.93
546_L578_L0.8530.93
228_I247_I0.8530.93
191_L195_I0.8490.93
161_E165_K0.8490.93
254_C265_Q0.8490.93
187_L191_L0.8490.93
529_I584_M0.8440.93
371_E383_I0.8430.93
210_Y578_L0.8400.93
601_Q604_K0.8390.92
525_R580_F0.8380.92
184_F219_V0.8360.92
292_T333_L0.8340.92
246_P249_F0.8320.92
373_Y379_N0.8310.92
430_R438_P0.8300.92
315_L323_Y0.8290.92
528_M544_D0.8270.92
633_Q641_G0.8270.92
125_G301_T0.8250.92
149_S152_I0.8240.92
179_V221_L0.8230.92
227_F253_E0.8220.92
549_T570_L0.8210.92
253_E256_Y0.8210.92
637_F642_S0.8200.92
344_V381_F0.8180.91
540_I581_V0.8170.91
218_T281_I0.8160.91
559_Q563_I0.8150.91
583_K586_Q0.8150.91
375_V378_L0.8140.91
249_F343_M0.8140.91
363_D471_D0.8140.91
624_D630_S0.8130.91
297_H325_D0.8120.91
440_S444_N0.8100.91
270_K350_Y0.8080.91
49_S52_N0.8060.91
660_L663_L0.8030.91
408_Y411_G0.8020.91
182_K561_N0.8010.91
587_F591_H0.8000.91
474_T548_R0.8000.91
48_Y104_V0.8000.91
225_F347_S0.7990.91
19_P32_N0.7970.90
201_G272_M0.7950.90
199_Y252_P0.7950.90
409_Q414_P0.7930.90
656_D660_L0.7920.90
349_R390_I0.7920.90
79_P152_I0.7920.90
259_T264_G0.7910.90
594_F639_L0.7910.90
521_E577_F0.7900.90
219_V281_I0.7900.90
613_V616_Y0.7890.90
157_E161_E0.7880.90
304_F309_N0.7870.90
64_N71_H0.7860.90
119_W231_R0.7860.90
515_N519_C0.7860.90
576_K579_E0.7860.90
431_F665_A0.7840.90
211_L216_I0.7830.90
529_I533_V0.7830.90
622_E627_T0.7820.90
635_V638_V0.7820.90
13_R16_D0.7800.89
270_K356_H0.7770.89
192_P206_Q0.7760.89
252_P269_F0.7750.89
27_D30_G0.7750.89
661_I665_A0.7730.89
476_E549_T0.7720.89
46_L84_A0.7720.89
634_L672_V0.7710.89
113_I251_S0.7710.89
95_L101_P0.7710.89
683_I688_R0.7700.89
399_E470_H0.7690.89
410_V414_P0.7690.89
188_R191_L0.7680.89
170_P173_D0.7680.89
154_P270_K0.7670.89
370_R379_N0.7630.88
227_F246_P0.7610.88
582_K586_Q0.7600.88
624_D629_S0.7600.88
229_D240_N0.7600.88
688_R691_K0.7590.88
36_F337_H0.7580.88
106_I248_N0.7570.88
111_K354_E0.7560.88
195_I198_T0.7520.88
245_D293_A0.7490.87
636_I662_I0.7470.87
271_K274_N0.7460.87
259_T265_Q0.7430.87
211_L281_I0.7430.87
510_P551_R0.7430.87
250_F289_Y0.7420.87
43_V85_Y0.7420.87
269_F285_I0.7410.87
361_R471_D0.7410.87
285_I357_V0.7400.87
191_L201_G0.7370.87
90_P97_L0.7360.87
304_F340_V0.7360.87
634_L664_N0.7320.86
154_P159_D0.7320.86
76_G79_P0.7310.86
572_E575_S0.7310.86
171_L395_K0.7310.86
159_D356_H0.7300.86
384_A391_L0.7300.86
158_W270_K0.7290.86
268_S271_K0.7290.86
587_F682_V0.7240.86
341_I383_I0.7240.86
601_Q606_F0.7230.86
199_Y272_M0.7220.86
62_V85_Y0.7210.85
627_T631_P0.7210.85
282_E391_L0.7200.85
43_V70_W0.7190.85
401_W425_R0.7190.85
179_V211_L0.7190.85
168_K393_Q0.7160.85
208_I281_I0.7160.85
40_A308_D0.7150.85
195_I206_Q0.7140.85
575_S578_L0.7140.85
430_R433_R0.7130.85
684_S688_R0.7130.85
531_L534_S0.7120.85
363_D399_E0.7110.85
290_N364_L0.7100.85
187_L192_P0.7080.84
446_L613_V0.7070.84
362_F396_L0.7070.84
411_G414_P0.7070.84
332_T405_Q0.7060.84
307_I311_A0.7050.84
635_V639_L0.7050.84
341_I345_L0.7040.84
316_Q325_D0.7040.84
634_L670_V0.7040.84
166_G356_H0.7020.84
333_L368_L0.7020.84
116_S253_E0.7020.84
422_G453_Y0.6990.84
524_K528_M0.6990.84
623_V628_W0.6980.84
37_S311_A0.6980.84
108_P307_I0.6930.83
151_V154_P0.6910.83
182_K560_D0.6900.83
468_T478_L0.6900.83
277_H283_V0.6900.83
45_L74_V0.6890.83
222_M542_G0.6880.83
184_F276_L0.6880.83
567_D573_R0.6880.83
22_S85_Y0.6870.83
156_F161_E0.6860.82
518_I522_K0.6860.82
634_L641_G0.6850.82
378_L417_W0.6830.82
326_F329_T0.6820.82
258_S264_G0.6800.82
523_Q527_F0.6800.82
602_G606_F0.6800.82
24_W29_D0.6800.82
611_K614_T0.6790.82
349_R388_D0.6780.82
424_Y427_S0.6770.82
627_T632_T0.6760.82
326_F405_Q0.6760.82
399_E471_D0.6750.81
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189_L196_R0.6740.81
236_K558_C0.6730.81
207_M211_L0.6720.81
352_V360_F0.6720.81
542_G548_R0.6720.81
220_E397_I0.6700.81
375_V379_N0.6700.81
229_D253_E0.6700.81
428_I467_V0.6700.81
596_R599_Y0.6690.81
469_S541_L0.6690.81
583_K683_I0.6680.81
74_V81_Q0.6680.81
79_P125_G0.6680.81
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391_L394_V0.6650.81
434_G442_I0.6630.80
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309_N323_Y0.6610.80
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603_K607_G0.6600.80
220_E539_M0.6600.80
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307_I310_T0.6570.80
214_L578_L0.6570.80
178_E242_W0.6570.80
203_A272_M0.6550.80
395_K418_A0.6550.80
361_R399_E0.6530.79
199_Y224_V0.6520.79
231_R234_T0.6510.79
407_G413_F0.6510.79
232_F245_D0.6510.79
564_T568_W0.6510.79
517_V521_E0.6500.79
45_L62_V0.6500.79
546_L570_L0.6500.79
212_K589_R0.6490.79
559_Q564_T0.6470.79
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560_D565_W0.6440.78
444_N447_L0.6440.78
225_F293_A0.6440.78
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599_Y603_K0.6420.78
544_D581_V0.6410.78
221_L272_M0.6410.78
418_A461_F0.6400.78
600_F603_K0.6390.78
249_F347_S0.6370.78
515_N518_I0.6360.77
681_L688_R0.6360.77
85_Y109_Y0.6350.77
408_Y413_F0.6350.77
639_L642_S0.6350.77
175_V217_T0.6340.77
109_Y312_Y0.6320.77
36_F68_D0.6320.77
195_I258_S0.6320.77
674_F679_W0.6310.77
252_P350_Y0.6290.77
388_D417_W0.6290.77
105_L108_P0.6270.77
184_F568_W0.6270.77
272_M355_M0.6260.76
681_L690_I0.6260.76
679_W684_S0.6250.76
232_F235_D0.6250.76
599_Y604_K0.6250.76
448_G451_D0.6240.76
458_K462_A0.6230.76
681_L691_K0.6210.76
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263_G266_V0.6200.76
35_L85_Y0.6190.76
468_T541_L0.6180.75
467_V531_L0.6180.75
366_A398_A0.6160.75
38_E337_H0.6160.75
39_N311_A0.6150.75
13_R75_P0.6150.75
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613_V637_F0.6130.75
88_Y102_N0.6130.75
615_F618_L0.6130.75
33_F74_V0.6120.75
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314_M324_L0.6120.75
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299_G304_F0.6050.74
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438_P441_E0.6040.74
341_I381_F0.6040.74
153_N160_D0.6040.74
613_V628_W0.6040.74
433_R523_Q0.6030.74
594_F663_L0.6030.74
385_L391_L0.6030.74
65_K71_H0.6030.74
185_T188_R0.6020.74
569_N573_R0.6000.73
659_F663_L0.5990.73
446_L533_V0.5990.73
579_E690_I0.5990.73
538_P588_Y0.5980.73
240_N245_D0.5980.73
659_F682_V0.5960.73
553_N558_C0.5960.73
365_A417_W0.5960.73
521_E547_S0.5950.73
172_K459_T0.5950.73
424_Y531_L0.5940.73
305_R311_A0.5910.72
23_N34_S0.5900.72
535_Q594_F0.5900.72
397_I539_M0.5900.72
165_K168_K0.5900.72
155_Y160_D0.5900.72
616_Y619_E0.5900.72
272_M275_E0.5890.72
180_H241_Y0.5890.72
638_V658_S0.5890.72
577_F581_V0.5890.72
596_R601_Q0.5880.72
684_S690_I0.5880.72
208_I211_L0.5880.72
49_S81_Q0.5870.72
54_K58_E0.5860.72
174_T282_E0.5860.72
249_F333_L0.5860.72
632_T635_V0.5850.71
407_G410_V0.5850.71
663_L666_N0.5840.71
246_P293_A0.5840.71
255_R265_Q0.5830.71
588_Y595_R0.5830.71
596_R602_G0.5820.71
309_N315_L0.5820.71
632_T637_F0.5820.71
616_Y623_V0.5820.71
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306_G310_T0.5800.71
230_Q245_D0.5800.71
535_Q596_R0.5790.71
291_H471_D0.5790.71
561_N564_T0.5780.71
230_Q329_T0.5780.71
61_E70_W0.5780.71
540_I544_D0.5780.71
482_N485_H0.5770.70
258_S265_Q0.5770.70
107_D110_A0.5760.70
447_L451_D0.5740.70
284_I359_G0.5740.70
83_Y107_D0.5730.70
424_Y428_I0.5730.70
570_L573_R0.5730.70
466_Y484_K0.5720.70
581_V587_F0.5720.70
560_D564_T0.5710.70
615_F619_E0.5710.70
422_G425_R0.5700.69
179_V566_F0.5700.69
340_V343_M0.5690.69
636_I642_S0.5690.69
633_Q640_E0.5680.69
230_Q233_L0.5680.69
479_V523_Q0.5680.69
371_E376_N0.5670.69
167_K274_N0.5670.69
559_Q565_W0.5670.69
533_V584_M0.5660.69
348_L385_L0.5650.69
53_Q58_E0.5650.69
29_D76_G0.5650.69
153_N158_W0.5650.69
191_L194_N0.5650.69
466_Y539_M0.5640.69
182_K199_Y0.5640.69
345_L384_A0.5640.69
556_A559_Q0.5640.69
341_I372_L0.5630.69
425_R429_R0.5630.69
112_A265_Q0.5620.68
197_G201_G0.5610.68
591_H595_R0.5610.68
683_I686_Y0.5610.68
17_P34_S0.5590.68
422_G466_Y0.5560.68
630_S633_Q0.5560.68
511_T516_V0.5550.67
433_R437_L0.5550.67
652_E656_D0.5550.67
157_E270_K0.5550.67
403_V406_G0.5540.67
74_V78_R0.5540.67
599_Y605_L0.5530.67
623_V626_K0.5530.67
407_G414_P0.5530.67
388_D396_L0.5530.67
558_C564_T0.5530.67
41_E89_G0.5530.67
187_L193_E0.5520.67
510_P513_D0.5520.67
315_L320_K0.5520.67
662_I674_F0.5520.67
219_V283_V0.5510.67
652_E655_A0.5510.67
257_S268_S0.5500.67
446_L637_F0.5490.67
587_F594_F0.5480.67
522_K526_N0.5470.66
635_V642_S0.5470.66
116_S229_D0.5460.66
54_K86_R0.5460.66
427_S438_P0.5450.66
480_S520_R0.5450.66
172_K597_E0.5440.66
602_G607_G0.5430.66
225_F228_I0.5430.66
308_D311_A0.5420.66
431_F435_E0.5410.66
311_A314_M0.5410.66
106_I149_S0.5410.66
233_L236_K0.5400.65
374_S379_N0.5390.65
555_N558_C0.5390.65
630_S634_L0.5390.65
565_W571_D0.5380.65
431_F442_I0.5380.65
244_Y399_E0.5370.65
446_L530_T0.5370.65
659_F665_A0.5370.65
329_T558_C0.5370.65
228_I293_A0.5360.65
87_V105_L0.5350.65
528_M532_L0.5340.65
510_P517_V0.5340.65
283_V358_D0.5340.65
550_Q564_T0.5330.64
67_G416_Q0.5320.64
68_D339_R0.5320.64
514_Q518_I0.5320.64
687_L691_K0.5310.64
149_S303_S0.5310.64
581_V584_M0.5300.64
678_K691_K0.5300.64
198_T258_S0.5300.64
333_L365_A0.5300.64
620_G628_W0.5290.64
559_Q568_W0.5290.64
559_Q562_E0.5280.64
332_T406_G0.5280.64
115_G233_L0.5280.64
33_F83_Y0.5280.64
286_D399_E0.5270.64
210_Y213_D0.5270.64
238_L558_C0.5270.64
473_F554_N0.5250.63
533_V661_I0.5250.63
657_D666_N0.5250.63
325_D329_T0.5250.63
116_S231_R0.5240.63
389_P392_S0.5220.63
187_L567_D0.5220.63
167_K273_V0.5220.63
120_N123_V0.5210.63
670_V673_K0.5190.62
668_N676_K0.5190.62
637_F663_L0.5190.62
594_F602_G0.5180.62
155_Y267_L0.5180.62
657_D662_I0.5170.62
563_I568_W0.5160.62
304_F333_L0.5160.62
150_V153_N0.5150.62
542_G546_L0.5150.62
432_W527_F0.5130.61
409_Q415_Y0.5120.61
48_Y84_A0.5120.61
177_Y214_L0.5120.61
373_Y405_Q0.5110.61
286_D361_R0.5110.61
373_Y378_L0.5080.61
678_K688_R0.5080.61
335_L368_L0.5080.61
116_S254_C0.5080.61
633_Q665_A0.5070.61
190_D206_Q0.5070.61
677_G686_Y0.5070.61
651_G659_F0.5070.61
161_E166_G0.5060.60
439_Y443_A0.5060.60
22_S30_G0.5060.60
244_Y470_H0.5050.60
15_G71_H0.5030.60
476_E521_E0.5030.60
367_A403_V0.5030.60
435_E438_P0.5020.60
447_L613_V0.5010.60
291_H363_D0.5010.60
370_R553_N0.5000.60
314_M334_N0.5000.60
201_G276_L0.5000.60
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2vr5A 5 0.9958 100 0.22 Contact Map
4j7rA 2 0.9471 100 0.25 Contact Map
1bf2A 1 0.9276 100 0.26 Contact Map
2wskA 1 0.9109 100 0.289 Contact Map
4j3vA 1 0.8733 100 0.333 Contact Map
2wanA 1 0.8287 100 0.34 Contact Map
3wdhA 1 0.8148 100 0.343 Contact Map
2e8yA 1 0.8245 100 0.347 Contact Map
2fhfA 1 0.8663 100 0.354 Contact Map
3fawA 1 0.8607 100 0.377 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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