GREMLIN Database
Q7LX98 - Maltooligosyltrehalose synthase (TreY)
UniProt: Q7LX98 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 732 (672)
Sequences: 1021 (704)
Seq/√Len: 27.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
15_T18_D7.8931.00
10_L36_L4.9501.00
299_L675_V4.4871.00
17_Y70_T4.4601.00
103_L118_H4.4291.00
128_I156_L4.2131.00
603_V622_L4.2041.00
603_V625_L4.0691.00
562_F565_D4.0241.00
586_T649_L3.8471.00
16_F67_G3.7881.00
529_I549_V3.6221.00
65_K69_F3.6171.00
23_L78_R3.5711.00
36_L75_A3.4721.00
24_D78_R3.3991.00
149_I186_L3.3641.00
44_P96_T3.2411.00
41_K57_E3.2271.00
310_T419_R3.0721.00
522_K554_D3.0381.00
248_N251_E3.0371.00
231_G259_L2.9581.00
8_L19_V2.9381.00
298_M435_L2.8671.00
64_G67_G2.8571.00
306_E433_F2.7931.00
41_K60_E2.6740.99
84_Q235_V2.6460.99
525_M553_I2.6400.99
65_K232_K2.6250.99
480_E572_K2.5960.99
102_D106_N2.5740.99
422_S471_I2.5570.99
526_I550_L2.5540.99
136_V141_L2.4980.99
300_L583_V2.4820.99
130_E151_Y2.4690.99
562_F566_F2.4560.99
100_L213_I2.4520.99
522_K550_L2.4130.99
34_L71_L2.3990.99
58_I68_Y2.3880.99
23_L75_A2.3770.99
230_I238_L2.3730.99
587_L591_S2.3710.99
133_L183_K2.3650.99
86_I240_I2.3470.99
74_E78_R2.3230.98
115_Y225_E2.3230.98
501_E505_Y2.3060.98
16_F39_I2.3060.98
603_V621_K2.3010.98
183_K187_L2.2930.98
257_R285_D2.2870.98
247_Y395_M2.2820.98
441_H661_Y2.2810.98
420_L471_I2.2700.98
27_K80_L2.2690.98
331_K405_F2.2550.98
306_E310_T2.2360.98
607_L615_M2.2270.98
17_Y20_I2.1560.97
27_K78_R2.1530.97
666_F674_T2.1350.97
93_I213_I2.1310.97
421_I503_R2.1310.97
456_L588_K2.0980.97
473_V573_I2.0940.97
229_I233_L2.0910.97
229_I232_K2.0620.97
332_K359_D2.0610.97
437_I675_V2.0600.97
24_D623_R2.0540.97
530_R546_E2.0520.97
301_V423_L2.0490.97
505_Y552_F2.0490.97
86_I230_I2.0440.96
208_A338_L2.0330.96
4_G32_S2.0210.96
464_S605_R2.0140.96
28_E630_T2.0100.96
313_Y499_N1.9910.96
467_V510_G1.9690.96
457_S464_S1.9690.96
565_D568_S1.9690.96
305_G309_L1.9640.96
361_L404_I1.9610.96
6_Y26_F1.9610.96
504_F525_M1.9550.95
17_Y67_G1.9450.95
492_L505_Y1.9310.95
131_D135_T1.9300.95
253_L268_V1.9160.95
297_N584_A1.8910.95
559_N562_F1.8890.94
326_L413_T1.8730.94
250_K281_D1.8660.94
563_R566_F1.8620.94
151_Y154_F1.8580.94
226_S230_I1.8510.94
559_N565_D1.8490.94
369_T398_Q1.8430.94
543_I547_N1.8300.93
83_I265_I1.8250.93
685_V690_S1.8190.93
630_T651_Q1.8110.93
323_I413_T1.8010.93
518_K554_D1.7960.93
28_E627_N1.7800.93
292_F591_S1.7770.92
234_L264_K1.7630.92
488_W565_D1.7570.92
508_L521_I1.7410.92
509_V570_E1.7270.91
476_E580_K1.7220.91
114_N219_L1.7180.91
28_E623_R1.7120.91
316_F489_H1.7090.91
118_H124_I1.6970.91
224_R259_L1.6890.90
42_A59_N1.6890.90
422_S472_S1.6830.90
423_L433_F1.6820.90
294_N428_S1.6770.90
144_V158_I1.6710.90
686_K689_I1.6710.90
412_T533_K1.6680.90
257_R266_I1.6670.90
604_W639_P1.6630.90
102_D111_K1.6630.90
106_N160_D1.6620.90
621_K625_L1.6470.89
33_H236_D1.6340.89
489_H501_E1.6270.89
327_I409_Y1.6250.89
578_Y636_L1.6240.89
92_A213_I1.6210.88
589_F597_I1.6200.88
65_K229_I1.6170.88
99_R115_Y1.5920.87
20_I70_T1.5760.87
361_L401_M1.5600.86
43_R211_D1.5510.86
484_R488_W1.5260.85
547_N551_D1.5240.85
415_F609_T1.5200.85
605_R622_L1.5180.85
330_S416_I1.5170.85
159_N190_Y1.5140.85
131_D136_V1.5030.84
504_F556_A1.5000.84
322_N325_E1.4970.84
292_F454_N1.4960.84
297_N422_S1.4950.84
569_F573_I1.4950.84
114_N221_E1.4930.84
559_N563_R1.4850.83
140_G143_K1.4780.83
16_F68_Y1.4770.83
647_K651_Q1.4750.83
444_N591_S1.4670.83
315_N486_I1.4630.83
687_E690_S1.4540.82
440_F675_V1.4480.82
150_E155_I1.4460.82
344_E354_Y1.4430.82
125_I194_T1.4370.81
150_E153_G1.4340.81
402_P405_F1.4330.81
141_L152_R1.4320.81
268_V284_V1.4260.81
39_I68_Y1.4220.81
297_N472_S1.4190.81
76_K236_D1.4160.80
360_F397_L1.4130.80
467_V507_T1.4090.80
75_A80_L1.4090.80
328_I332_K1.4070.80
635_E638_D1.4050.80
58_I64_G1.3920.79
500_D545_Y1.3910.79
586_T690_S1.3880.79
39_I82_I1.3800.79
644_L648_K1.3800.79
112_Y115_Y1.3790.79
220_D255_K1.3790.79
20_I23_L1.3740.78
467_V608_L1.3720.78
312_F482_E1.3550.77
39_I84_Q1.3540.77
293_L455_T1.3530.77
84_Q230_I1.3490.77
14_F61_E1.3460.77
629_L632_K1.3430.77
295_Y443_F1.3410.77
100_L512_Y1.3380.76
130_E152_R1.3340.76
267_Y300_L1.3280.76
577_G581_S1.3230.76
473_V576_F1.3200.75
68_Y82_I1.3090.75
11_N14_F1.2990.74
300_L587_L1.2910.74
666_F676_L1.2900.74
234_L260_V1.2780.73
544_E547_N1.2740.73
208_A214_A1.2740.73
250_K254_D1.2650.72
668_F673_V1.2450.71
402_P461_T1.2440.71
407_K411_D1.2370.71
603_V643_M1.2310.70
423_L434_S1.2300.70
228_E232_K1.2230.70
130_E154_F1.2220.70
496_I552_F1.2210.69
465_E588_K1.2170.69
55_H98_W1.2130.69
57_E60_E1.2110.69
425_E461_T1.2110.69
207_F367_Y1.2100.69
664_L687_E1.2070.69
550_L554_D1.2050.68
581_S604_W1.2040.68
668_F671_G1.2010.68
327_I413_T1.2010.68
331_K524_H1.2000.68
197_K540_N1.1970.68
292_F296_V1.1960.68
622_L625_L1.1870.67
586_T590_L1.1860.67
645_Y649_L1.1750.66
535_H545_Y1.1750.66
140_G144_V1.1740.66
238_L260_V1.1670.66
488_W492_L1.1660.66
636_L639_P1.1640.66
652_L656_Y1.1640.66
440_F444_N1.1610.66
23_L71_L1.1600.65
291_D452_S1.1590.65
578_Y641_V1.1580.65
425_E428_S1.1530.65
208_A533_K1.1470.65
291_D453_M1.1440.64
234_L238_L1.1410.64
6_Y461_T1.1360.64
332_K362_A1.1330.64
224_R255_K1.1320.64
678_S687_E1.1320.64
207_F271_I1.1270.63
590_L677_F1.1200.63
562_F572_K1.1150.62
36_L82_I1.1070.62
357_L401_M1.1040.62
577_G604_W1.1040.62
158_I471_I1.1030.61
10_L75_A1.1020.61
585_T646_V1.1020.61
20_I74_E1.0990.61
132_E195_Y1.0960.61
22_N26_F1.0920.61
644_L647_K1.0900.61
145_Q150_E1.0900.61
509_V573_I1.0860.60
349_L393_G1.0850.60
213_I512_Y1.0840.60
74_E77_S1.0830.60
131_D139_K1.0820.60
93_I154_F1.0820.60
350_L422_S1.0810.60
456_L465_E1.0800.60
661_Y677_F1.0780.60
507_T521_I1.0740.59
457_S467_V1.0740.59
519_E523_N1.0710.59
489_H498_K1.0700.59
309_L433_F1.0680.59
674_T689_I1.0680.59
625_L640_R1.0670.59
380_R384_K1.0670.59
565_D572_K1.0650.59
131_D141_L1.0640.59
240_I335_A1.0640.59
55_H396_R1.0610.58
590_L688_K1.0610.58
57_E551_D1.0550.58
652_L657_S1.0510.58
133_L182_I1.0500.58
400_Y403_A1.0470.57
353_N536_T1.0460.57
52_V398_Q1.0450.57
675_V690_S1.0450.57
126_L652_L1.0400.57
216_R219_L1.0380.57
18_D21_E1.0340.56
16_F62_L1.0320.56
92_A100_L1.0280.56
583_V666_F1.0250.56
203_Y524_H1.0240.56
638_D641_V1.0220.56
312_F485_V1.0220.56
405_F524_H1.0200.55
207_F426_V1.0170.55
105_K160_D1.0170.55
293_L461_T1.0170.55
295_Y444_N1.0130.55
266_I285_D1.0120.55
685_V688_K1.0120.55
484_R565_D1.0050.54
423_L428_S1.0030.54
27_K654_R1.0020.54
501_E552_F1.0010.54
566_F569_F0.9970.54
10_L19_V0.9970.54
25_Y622_L0.9960.54
186_L194_T0.9950.53
588_K597_I0.9940.53
577_G638_D0.9840.53
123_K187_L0.9830.53
240_I494_P0.9820.53
133_L186_L0.9750.52
55_H99_R0.9740.52
203_Y331_K0.9670.51
328_I363_C0.9670.51
75_A82_I0.9660.51
662_K678_S0.9660.51
142_I146_K0.9640.51
271_I367_Y0.9630.51
353_N393_G0.9620.51
630_T647_K0.9540.50
32_S595_P0.9530.50
305_G434_S0.9520.50
492_L552_F0.9520.50
477_I480_E0.9510.50
6_Y331_K0.9490.50
524_H528_V0.9480.50
142_I149_I0.9460.50
238_L597_I0.9430.50
203_Y549_V0.9430.50
367_Y426_V0.9420.49
497_D535_H0.9410.49
214_A644_L0.9370.49
213_I361_L0.9360.49
605_R646_V0.9350.49
315_N645_Y0.9330.49
604_W641_V0.9310.49
53_V108_K0.9300.49
10_L39_I0.9300.49
514_G606_F0.9290.49
40_L230_I0.9290.49
260_V264_K0.9260.48
33_H83_I0.9250.48
253_L361_L0.9250.48
125_I200_Y0.9220.48
68_Y72_V0.9190.48
240_I299_L0.9170.48
660_D680_I0.9110.47
345_R392_K0.9100.47
182_I185_L0.9090.47
496_I548_K0.9090.47
44_P61_E0.9080.47
336_N358_V0.9080.47
473_V580_K0.9060.47
497_D534_V0.9050.47
282_W370_Y0.9040.47
629_L643_M0.9010.46
433_F465_E0.8990.46
208_A350_L0.8990.46
684_E687_E0.8980.46
522_K526_I0.8980.46
125_I134_D0.8970.46
497_D500_D0.8950.46
432_R439_D0.8950.46
577_G639_P0.8890.45
240_I243_I0.8870.45
72_V75_A0.8850.45
182_I194_T0.8810.45
492_L501_E0.8800.45
11_N18_D0.8790.45
19_V71_L0.8770.45
93_I100_L0.8760.45
509_V569_F0.8710.44
444_N675_V0.8670.44
362_A404_I0.8670.44
585_T588_K0.8650.44
40_L158_I0.8630.44
4_G33_H0.8610.43
471_I476_E0.8610.43
559_N566_F0.8590.43
264_K291_D0.8560.43
82_I408_G0.8550.43
308_E312_F0.8540.43
423_L461_T0.8530.43
22_N623_R0.8530.43
285_D451_I0.8520.43
583_V690_S0.8490.43
418_N499_N0.8490.43
92_A419_R0.8490.43
100_L443_F0.8490.43
309_L420_L0.8480.42
10_L58_I0.8480.42
203_Y461_T0.8470.42
298_M434_S0.8450.42
328_I362_A0.8440.42
251_E255_K0.8440.42
224_R493_R0.8430.42
260_V266_I0.8420.42
69_F478_P0.8420.42
577_G580_K0.8340.41
587_L675_V0.8320.41
523_N526_I0.8310.41
604_W638_D0.8310.41
272_L291_D0.8300.41
210_N342_D0.8260.41
134_D194_T0.8260.41
492_L556_A0.8250.41
658_L681_V0.8250.41
59_N62_L0.8250.41
125_I339_F0.8220.41
156_L193_L0.8190.40
421_I507_T0.8190.40
342_D425_E0.8170.40
271_I426_V0.8170.40
342_D402_P0.8170.40
125_I192_R0.8170.40
331_K346_L0.8160.40
683_R690_S0.8140.40
86_I92_A0.8140.40
475_S568_S0.8110.40
33_H408_G0.8110.40
202_N641_V0.8100.40
503_R524_H0.8090.40
158_I162_G0.8080.40
203_Y301_V0.8060.39
310_T581_S0.8030.39
398_Q402_P0.8020.39
664_L678_S0.8010.39
305_G433_F0.8010.39
589_F649_L0.8000.39
305_G578_Y0.8000.39
327_I334_V0.8000.39
10_L649_L0.7990.39
636_L641_V0.7990.39
334_V338_L0.7980.39
100_L577_G0.7980.39
208_A412_T0.7940.39
646_V649_L0.7920.38
272_L278_L0.7910.38
65_K233_L0.7900.38
158_I464_S0.7900.38
309_L434_S0.7870.38
401_M497_D0.7870.38
536_T652_L0.7850.38
566_F570_E0.7840.38
58_I67_G0.7840.38
134_D353_N0.7830.38
215_V220_D0.7830.38
133_L137_I0.7800.38
17_Y74_E0.7790.37
605_R615_M0.7750.37
68_Y233_L0.7750.37
471_I606_F0.7740.37
120_D209_V0.7720.37
134_D182_I0.7720.37
201_P210_N0.7700.37
402_P422_S0.7700.37
331_K408_G0.7690.37
584_A605_R0.7690.37
565_D569_F0.7680.37
670_R673_V0.7670.37
14_F202_N0.7670.37
100_L404_I0.7670.37
349_L392_K0.7660.37
25_Y602_E0.7660.37
14_F18_D0.7630.36
214_A402_P0.7600.36
196_W367_Y0.7590.36
474_L582_L0.7590.36
161_E585_T0.7570.36
481_W509_V0.7570.36
341_G403_A0.7560.36
16_F233_L0.7550.36
496_I581_S0.7540.36
642_K653_R0.7540.36
11_N191_Y0.7530.36
243_I253_L0.7520.36
380_R383_D0.7510.35
197_K209_V0.7500.35
76_K80_L0.7490.35
381_E385_E0.7490.35
318_G486_I0.7490.35
93_I101_M0.7460.35
6_Y203_Y0.7450.35
587_L649_L0.7430.35
361_L400_Y0.7430.35
434_S478_P0.7430.35
345_R396_R0.7400.35
105_K188_M0.7400.35
73_K519_E0.7390.35
301_V461_T0.7390.35
141_L144_V0.7390.35
71_L82_I0.7380.35
10_L62_L0.7370.35
313_Y317_I0.7360.34
469_A580_K0.7360.34
488_W584_A0.7350.34
364_M401_M0.7350.34
216_R652_L0.7350.34
518_K522_K0.7350.34
444_N467_V0.7350.34
68_Y71_L0.7340.34
500_D535_H0.7340.34
36_L420_L0.7340.34
136_V420_L0.7340.34
208_A294_N0.7340.34
423_L472_S0.7330.34
288_T342_D0.7330.34
315_N519_E0.7320.34
54_D57_E0.7310.34
457_S461_T0.7300.34
284_V519_E0.7300.34
4_G454_N0.7300.34
464_S467_V0.7280.34
279_R370_Y0.7270.34
43_R96_T0.7270.34
306_E419_R0.7260.34
144_V147_D0.7260.34
16_F80_L0.7250.34
41_K53_V0.7230.34
566_F689_I0.7220.34
84_Q100_L0.7220.34
304_S483_E0.7190.33
627_N686_K0.7190.33
130_E141_L0.7180.33
331_K461_T0.7150.33
261_G360_F0.7140.33
496_I668_F0.7130.33
240_I284_V0.7130.33
158_I191_Y0.7120.33
607_L622_L0.7120.33
210_N341_G0.7110.33
628_N640_R0.7100.33
105_K163_V0.7100.33
101_M345_R0.7090.33
680_I685_V0.7090.33
293_L300_L0.7080.33
13_K333_L0.7080.33
532_A608_L0.7080.33
125_I202_N0.7070.32
73_K76_K0.7060.32
313_Y316_F0.7060.32
581_S606_F0.7060.32
343_I358_V0.7050.32
500_D529_I0.7050.32
581_S639_P0.7030.32
586_T645_Y0.7000.32
380_R385_E0.7000.32
581_S638_D0.7000.32
471_I510_G0.6990.32
202_N500_D0.6980.32
3_I32_S0.6980.32
471_I580_K0.6970.32
95_H213_I0.6970.32
583_V586_T0.6960.32
685_V689_I0.6940.32
343_I357_L0.6940.32
265_I401_M0.6920.32
518_K553_I0.6920.32
532_A535_H0.6910.31
109_N190_Y0.6910.31
387_K390_D0.6900.31
394_I643_M0.6890.31
686_K690_S0.6870.31
457_S605_R0.6870.31
4_G382_C0.6860.31
542_N616_P0.6860.31
636_L640_R0.6850.31
408_G685_V0.6840.31
438_D442_N0.6840.31
312_F315_N0.6840.31
126_L235_V0.6840.31
75_A488_W0.6830.31
132_E135_T0.6820.31
79_G280_D0.6800.31
62_L294_N0.6780.31
438_D672_K0.6780.31
405_F422_S0.6770.31
94_H213_I0.6760.30
208_A404_I0.6760.30
461_T524_H0.6740.30
293_L298_M0.6740.30
26_F34_L0.6740.30
508_L557_F0.6730.30
18_D508_L0.6720.30
132_E159_N0.6720.30
266_I284_V0.6700.30
100_L160_D0.6690.30
471_I567_E0.6680.30
681_V684_E0.6670.30
243_I457_S0.6670.30
153_G156_L0.6670.30
350_L357_L0.6670.30
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299_L437_I0.6660.30
622_L643_M0.6660.30
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455_T553_I0.6650.30
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180_E184_K0.6630.30
215_V312_F0.6620.30
456_L585_T0.6620.30
6_Y602_E0.6620.30
496_I659_N0.6620.30
182_I186_L0.6620.30
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208_A213_I0.6570.29
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453_M465_E0.6280.27
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371_L398_Q0.6250.27
618_D621_K0.6250.27
487_Y565_D0.6250.27
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72_V82_I0.6220.27
58_I550_L0.6220.27
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190_Y541_P0.6210.27
562_F569_F0.6200.27
124_I135_T0.6200.27
196_W271_I0.6200.27
93_I208_A0.6190.27
328_I573_I0.6180.27
203_Y405_F0.6170.27
618_D622_L0.6160.27
408_G413_T0.6160.27
209_V657_S0.6160.27
346_L536_T0.6150.27
420_L434_S0.6150.27
108_K478_P0.6150.27
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292_F505_Y0.6140.27
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332_K358_V0.6100.26
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213_I253_L0.6090.26
33_H199_D0.6070.26
16_F316_F0.6070.26
52_V59_N0.6070.26
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303_G597_I0.6060.26
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8_L36_L0.5940.25
75_A584_A0.5930.25
53_V96_T0.5920.25
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328_I408_G0.5910.25
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518_K558_E0.5880.25
590_L649_L0.5870.25
526_I529_I0.5860.25
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407_K527_K0.5860.25
481_W502_Y0.5860.25
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635_E640_R0.5700.24
408_G503_R0.5700.24
108_K299_L0.5700.24
207_F407_K0.5690.24
581_S641_V0.5690.24
35_Y398_Q0.5690.24
452_S572_K0.5680.24
4_G7_R0.5680.24
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213_I404_I0.5650.24
200_Y347_S0.5650.24
34_L95_H0.5650.24
142_I152_R0.5650.24
73_K302_D0.5640.24
265_I453_M0.5640.24
136_V151_Y0.5630.24
217_V226_S0.5620.24
301_V428_S0.5620.24
203_Y313_Y0.5610.24
411_D426_V0.5610.24
299_L440_F0.5610.24
128_I243_I0.5610.24
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422_S434_S0.5600.24
106_N111_K0.5600.24
68_Y597_I0.5600.24
209_V490_D0.5590.24
578_Y637_S0.5590.24
99_R126_L0.5580.23
16_F604_W0.5570.23
119_Y300_L0.5570.23
77_S655_E0.5570.23
311_K437_I0.5570.23
6_Y408_G0.5560.23
32_S403_A0.5560.23
40_L215_V0.5550.23
240_I547_N0.5550.23
333_L337_Q0.5550.23
301_V331_K0.5540.23
43_R93_I0.5540.23
465_E585_T0.5530.23
358_V397_L0.5530.23
100_L362_A0.5520.23
428_S452_S0.5510.23
84_Q345_R0.5510.23
439_D443_F0.5510.23
424_N488_W0.5510.23
519_E554_D0.5500.23
405_F461_T0.5500.23
55_H335_A0.5500.23
256_L396_R0.5500.23
42_A62_L0.5490.23
102_D591_S0.5480.23
398_Q404_I0.5480.23
207_F402_P0.5470.23
32_S420_L0.5470.23
233_L313_Y0.5470.23
407_K426_V0.5470.23
335_A529_I0.5470.23
314_E571_K0.5460.23
4_G675_V0.5450.23
574_V645_Y0.5450.23
27_K357_L0.5450.23
437_I666_F0.5450.23
311_K315_N0.5450.23
464_S609_T0.5440.23
267_Y451_I0.5440.23
268_V329_Q0.5440.23
148_K664_L0.5440.23
578_Y638_D0.5440.23
424_N475_S0.5430.23
558_E562_F0.5430.23
133_L187_L0.5430.23
118_H295_Y0.5420.23
139_K519_E0.5420.23
350_L393_G0.5410.23
124_I376_I0.5400.23
580_K584_A0.5400.23
477_I573_I0.5390.22
378_G382_C0.5390.22
111_K225_E0.5390.22
231_G234_L0.5390.22
120_D586_T0.5390.22
35_Y465_E0.5390.22
567_E570_E0.5380.22
309_L330_S0.5380.22
33_H81_G0.5380.22
100_L253_L0.5380.22
123_K357_L0.5380.22
431_R594_V0.5380.22
59_N210_N0.5370.22
62_L403_A0.5370.22
210_N338_L0.5370.22
208_A365_K0.5360.22
86_I422_S0.5360.22
485_V488_W0.5360.22
334_V408_G0.5360.22
68_Y80_L0.5350.22
657_S686_K0.5350.22
134_D183_K0.5340.22
78_R594_V0.5330.22
5_T8_L0.5330.22
319_R597_I0.5330.22
267_Y291_D0.5320.22
111_K240_I0.5320.22
32_S298_M0.5310.22
580_K676_L0.5310.22
201_P361_L0.5300.22
58_I158_I0.5300.22
188_M498_K0.5300.22
240_I374_E0.5290.22
628_N632_K0.5290.22
541_P629_L0.5290.22
60_E387_K0.5280.22
23_L80_L0.5270.22
303_G523_N0.5270.22
253_L346_L0.5270.22
154_F253_L0.5260.22
25_Y451_I0.5260.22
306_E320_K0.5250.22
56_S315_N0.5240.22
57_E445_Q0.5240.22
61_E65_K0.5240.22
3_I253_L0.5230.22
310_T329_Q0.5220.22
294_N423_L0.5210.22
26_F461_T0.5210.22
187_L192_R0.5210.22
524_H609_T0.5200.21
347_S568_S0.5200.21
163_V179_K0.5200.21
536_T689_I0.5190.21
52_V55_H0.5190.21
203_Y525_M0.5190.21
314_E319_R0.5190.21
15_T508_L0.5180.21
181_D184_K0.5180.21
578_Y604_W0.5180.21
102_D115_Y0.5170.21
214_A505_Y0.5160.21
464_S581_S0.5150.21
357_L393_G0.5150.21
303_G308_E0.5150.21
72_V388_L0.5150.21
408_G629_L0.5140.21
40_L457_S0.5140.21
261_G461_T0.5140.21
542_N566_F0.5130.21
340_K354_Y0.5130.21
15_T20_I0.5130.21
346_L461_T0.5130.21
109_N188_M0.5130.21
525_M550_L0.5120.21
209_V238_L0.5120.21
181_D185_L0.5110.21
152_R528_V0.5110.21
73_K651_Q0.5110.21
333_L338_L0.5110.21
442_N590_L0.5110.21
292_F588_K0.5110.21
100_L636_L0.5110.21
12_K124_I0.5100.21
18_D191_Y0.5100.21
35_Y50_Y0.5100.21
56_S228_E0.5100.21
335_A343_I0.5100.21
221_E225_E0.5100.21
99_R225_E0.5090.21
23_L517_N0.5090.21
331_K472_S0.5080.21
577_G641_V0.5080.21
68_Y398_Q0.5080.21
105_K115_Y0.5080.21
143_K146_K0.5070.21
235_V315_N0.5070.21
313_Y424_N0.5070.21
41_K61_E0.5070.21
219_L279_R0.5060.21
403_A545_Y0.5060.21
292_F400_Y0.5060.21
264_K424_N0.5060.21
471_I605_R0.5060.21
601_T605_R0.5060.21
266_I283_K0.5050.21
247_Y553_I0.5050.21
20_I655_E0.5050.21
52_V396_R0.5050.21
329_Q431_R0.5040.21
201_P273_S0.5040.21
156_L473_V0.5040.21
545_Y579_M0.5040.21
352_V389_K0.5040.21
347_S361_L0.5040.21
496_I577_G0.5030.21
21_E657_S0.5030.21
484_R487_Y0.5030.21
40_L101_M0.5020.21
562_F567_E0.5020.21
505_Y556_A0.5020.21
238_L264_K0.5020.21
273_S461_T0.5020.21
126_L478_P0.5020.21
465_E619_F0.5010.21
643_M647_K0.5010.21
185_L353_N0.5010.21
68_Y575_Y0.5010.21
230_I268_V0.5000.20
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1iv8A 1 0.9208 100 0.32 Contact Map
3hjeA 1 0.9262 100 0.325 Contact Map
2wc7A 2 0.556 100 0.869 Contact Map
1j0hA 2 0.5505 100 0.869 Contact Map
1ea9C 2 0.5492 100 0.871 Contact Map
2z1kA 2 0.5738 100 0.871 Contact Map
1wzlA 2 0.5533 100 0.873 Contact Map
4aefA 1 0.5546 100 0.874 Contact Map
4aeeA 1 0.5601 100 0.874 Contact Map
3czgA 1 0.6407 100 0.88 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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