GREMLIN Database
Q7LX97 - Uncharacterized protein
UniProt: Q7LX97 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 123 (113)
Sequences: 1874 (1458)
Seq/√Len: 137.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
43_F80_R4.5831.00
35_Y72_A3.6991.00
30_T33_N2.5111.00
6_I105_M2.1971.00
71_T98_I2.1711.00
34_L66_N2.1271.00
7_C30_T2.0381.00
68_S96_I1.9991.00
38_L73_S1.8871.00
89_P92_L1.8771.00
39_R76_Y1.8591.00
37_F41_L1.8581.00
96_I100_N1.8231.00
44_I48_I1.8101.00
72_A89_P1.6031.00
64_I92_L1.5651.00
68_S99_A1.5581.00
42_A74_R1.5391.00
30_T96_I1.5381.00
15_D107_H1.5111.00
101_D119_G1.4861.00
78_E116_E1.4861.00
72_A95_S1.4851.00
108_N111_H1.4751.00
109_K113_K1.4611.00
47_N51_F1.4611.00
44_I47_N1.4561.00
29_T33_N1.4341.00
7_C97_C1.4201.00
65_D68_S1.3901.00
32_I92_L1.3811.00
94_A115_L1.3741.00
34_L56_E1.3491.00
7_C102_F1.3391.00
78_E82_M1.3231.00
31_C64_I1.3221.00
41_L48_I1.2951.00
87_E111_H1.2821.00
14_I18_R1.2821.00
64_I68_S1.2561.00
88_D111_H1.2351.00
38_L70_K1.2061.00
6_I103_S1.1800.99
14_I47_N1.1790.99
75_I98_I1.1700.99
12_V15_D1.1620.99
35_Y89_P1.1540.99
79_L114_R1.1310.99
86_I111_H1.1300.99
86_I115_L1.1250.99
7_C28_Y1.1200.99
13_L29_T1.1180.99
45_G48_I1.0980.99
111_H114_R1.0950.99
13_L55_I1.0940.99
97_C104_L1.0810.99
73_S77_A1.0270.99
71_T74_R1.0170.98
79_L91_L1.0130.98
65_D99_A1.0120.98
28_Y62_V0.9910.98
47_N50_E0.9890.98
46_K50_E0.9830.98
35_Y64_I0.9810.98
79_L86_I0.9800.98
72_A92_L0.9750.98
84_E114_R0.9680.98
11_D111_H0.9630.98
62_V100_N0.9630.98
22_K27_Y0.9590.98
31_C69_L0.9470.98
42_A73_S0.9430.98
35_Y95_S0.9410.97
45_G49_D0.9280.97
42_A77_A0.9230.97
11_D112_F0.9160.97
74_R78_E0.9120.97
39_R80_R0.8970.97
7_C96_I0.8930.97
65_D100_N0.8860.96
77_A81_K0.8770.96
68_S100_N0.8750.96
85_I91_L0.8630.96
22_K26_G0.8530.96
29_T59_L0.8520.96
12_V107_H0.8380.95
38_L48_I0.8320.95
6_I102_F0.8180.94
74_R98_I0.8170.94
75_I86_I0.8100.94
41_L51_F0.7970.94
62_V102_F0.7940.93
86_I114_R0.7850.93
15_D18_R0.7750.93
29_T34_L0.7710.92
76_Y91_L0.7650.92
16_A19_N0.7600.92
41_L47_N0.7580.92
71_T99_A0.7570.92
98_I115_L0.7490.91
79_L85_I0.7460.91
35_Y73_S0.7430.91
28_Y60_N0.7380.91
72_A91_L0.7290.90
64_I69_L0.7260.90
37_F56_E0.7250.90
12_V105_M0.7140.89
23_K26_G0.7120.89
38_L52_K0.7080.89
67_N70_K0.7070.89
67_N99_A0.7030.89
48_I51_F0.6990.88
79_L83_G0.6990.88
115_L118_Y0.6980.88
34_L38_L0.6950.88
82_M116_E0.6930.88
38_L42_A0.6860.87
14_I41_L0.6850.87
31_C65_D0.6840.87
98_I118_Y0.6790.87
89_P111_H0.6770.87
92_L96_I0.6760.87
48_I52_K0.6690.86
75_I78_E0.6590.85
69_L73_S0.6580.85
32_I89_P0.6530.85
14_I37_F0.6500.84
35_Y92_L0.6470.84
76_Y80_R0.6440.84
14_I17_F0.6430.84
76_Y88_D0.6420.84
87_E95_S0.6360.83
79_L111_H0.6360.83
35_Y91_L0.6340.83
110_K113_K0.6310.83
49_D53_S0.6300.82
106_T109_K0.6100.80
116_E119_G0.6040.80
47_N55_I0.5930.79
11_D107_H0.5790.77
49_D109_K0.5790.77
8_L96_I0.5750.76
21_I113_K0.5700.76
87_E91_L0.5670.75
30_T97_C0.5640.75
43_F81_K0.5610.75
39_R43_F0.5600.74
49_D52_K0.5600.74
47_N52_K0.5590.74
31_C63_C0.5570.74
38_L51_F0.5550.74
30_T61_V0.5470.73
20_D107_H0.5460.73
13_L17_F0.5460.73
37_F51_F0.5440.72
10_T30_T0.5430.72
29_T55_I0.5340.71
15_D19_N0.5290.70
79_L87_E0.5260.70
14_I44_I0.5200.69
33_N89_P0.5190.69
57_L74_R0.5170.69
91_L111_H0.5120.68
63_C106_T0.5120.68
75_I91_L0.5080.67
87_E108_N0.5070.67
53_S57_L0.5020.66
104_L118_Y0.5020.66
68_S95_S0.5000.66
75_I94_A0.5000.66
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1v96A 2 0.9837 99.9 0.441 Contact Map
3h87A 3 0.9675 99.9 0.456 Contact Map
3dboB 1 0.935 99.9 0.467 Contact Map
3zvkA 3 0.9675 99.8 0.504 Contact Map
3tndA 3 0.9756 99.8 0.511 Contact Map
2h1cA 2 0.9593 99.8 0.529 Contact Map
4chgA 2 0.9431 99.7 0.554 Contact Map
1w8iA 2 0.935 99.7 0.584 Contact Map
3i8oA 2 0.9512 99.5 0.634 Contact Map
2fe1A 2 0.8862 99.5 0.637 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0057 seconds.