Q7LX72 - SULSO - GREMLIN Contacts

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Q7LX72 - L-lactate permease

UniProt:	Q7LX72	Sequences: MYIQPLNPTGNVGLTILASLTPIIALLILLAGLRITAWLATLIGSIITILVATFVWGTPIIQVSYAWLIGALVGTWAISWIVFWGLTIYNTLVLTGKFDAFRDWIVRNSTNDARVQAIVLAWSLGALFEGLVGFGYPWAFIAPLLIYLGFDDLKALQVSALANNAPVSFGALGTPIIILASVTGLPLLFISSSVAKVVAILALLPPWILLYLVDKWRGIREAWPIAILGSLSYILGQYPVASFIGPYLPDITGSLISFVILLLFLRVWRPKRVLSLRSVQPNGGESKKYSTKDVIEALSAFIVLIIVVTLWTGPWSPLTKFSLVTLSQTAYSSLLHKNVGVSFAFNPFVAGTSILVSWIIISLVLRASPRIMGEAIKRSFHQYWGGILTGIFVVGLAYVFNFSGMAYSLAWKTSDLGIAFIIVSPLFGWIGCALSGSNTSTNALFGAFQVTTARLTGLPVGLPPALNSVGAELAKPVAPQTASAGVSTTKYVRKEGIVIRKNLPWAIGILIYLILIGVLYAFLAPSLFVH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	530 (504)
Sequences:	1596 (1032)
Seq/√Len:	46.0

ECOLI - GLCA LLDP
BACSU - LUTP LCTP
HALSA - Q9HHI2
SULSO - Q7LX72

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
494_K	497_I	6.451	1.00
50_L	54_F	5.109	1.00
25_A	47_I	4.845	1.00
466_L	517_G	4.371	1.00
420_F	424_S	4.277	1.00
381_H	384_W	3.965	1.00
236_G	256_I	3.909	1.00
263_L	267_V	3.861	1.00
359_I	363_L	3.810	1.00
53_T	63_V	3.772	1.00
221_E	272_R	3.733	1.00
49_I	63_V	3.581	1.00
228_L	264_F	3.356	1.00
49_I	399_V	3.237	1.00
426_L	510_L	3.221	1.00
377_K	381_H	3.170	1.00
28_I	33_L	3.123	1.00
161_L	212_L	3.062	1.00
510_L	514_I	3.035	1.00
179_L	446_G	3.026	1.00
95_T	367_A	2.976	1.00
94_L	378_R	2.928	1.00
110_T	115_V	2.920	1.00
123_S	257_S	2.886	1.00
25_A	29_L	2.876	1.00
90_N	382_Q	2.762	1.00
71_A	391_I	2.701	1.00
45_S	67_W	2.694	1.00
196_K	242_S	2.662	1.00
18_A	55_V	2.610	1.00
307_V	356_V	2.605	1.00
51_V	55_V	2.529	1.00
458_L	463_P	2.520	1.00
214_D	218_G	2.497	1.00
361_I	365_L	2.404	1.00
35_I	39_L	2.377	1.00
94_L	371_I	2.333	1.00
292_K	296_E	2.294	1.00
156_L	485_G	2.188	1.00
515_L	519_L	2.187	1.00
232_S	260_I	2.179	1.00
357_S	361_I	2.179	1.00
299_S	364_V	2.158	1.00
68_L	335_L	2.155	1.00
176_I	194_V	2.144	1.00
370_R	374_E	2.142	1.00
235_L	239_P	2.105	1.00
511_I	515_L	2.100	1.00
362_S	372_M	2.089	1.00
446_G	464_P	2.080	1.00
400_F	406_A	2.073	1.00
368_S	371_I	2.067	1.00
289_Y	293_D	2.059	0.99
146_I	489_T	2.055	0.99
450_V	464_P	2.036	0.99
196_K	238_Y	2.034	0.99
426_L	514_I	2.023	0.99
295_I	299_S	2.023	0.99
319_T	322_S	2.014	0.99
193_S	461_G	2.005	0.99
46_I	50_L	1.975	0.99
373_G	377_K	1.960	0.99
296_E	366_R	1.948	0.99
16_I	412_K	1.917	0.99
42_L	392_F	1.882	0.99
179_L	464_P	1.877	0.99
167_V	438_N	1.875	0.99
224_P	268_W	1.873	0.99
28_I	32_G	1.856	0.99
94_L	374_E	1.843	0.99
29_L	43_I	1.822	0.99
369_P	373_G	1.807	0.99
252_T	256_I	1.807	0.99
88_I	358_W	1.805	0.99
203_L	234_I	1.800	0.99
186_P	189_F	1.790	0.99
239_P	243_F	1.779	0.98
312_T	316_S	1.763	0.98
121_A	209_L	1.762	0.98
99_D	102_R	1.759	0.98
439_T	474_A	1.742	0.98
210_L	222_A	1.736	0.98
207_W	226_A	1.729	0.98
232_S	257_S	1.724	0.98
276_L	279_V	1.723	0.98
204_L	207_W	1.712	0.98
177_I	246_P	1.704	0.98
313_G	316_S	1.675	0.98
29_L	35_I	1.663	0.98
319_T	323_L	1.619	0.97
311_W	353_S	1.618	0.97
475_K	481_T	1.618	0.97
240_V	252_T	1.618	0.97
36_T	40_A	1.616	0.97
194_V	469_V	1.615	0.97
295_I	302_I	1.613	0.97
104_W	298_L	1.597	0.97
115_V	225_I	1.589	0.97
259_V	263_L	1.576	0.97
79_S	387_I	1.574	0.97
232_S	256_I	1.568	0.97
40_A	127_L	1.564	0.97
293_D	296_E	1.562	0.97
168_S	194_V	1.533	0.96
318_L	321_F	1.524	0.96
117_A	158_V	1.519	0.96
327_S	332_S	1.504	0.96
290_S	293_D	1.496	0.96
203_L	230_S	1.495	0.96
438_N	471_A	1.474	0.95
333_S	340_G	1.465	0.95
125_G	162_A	1.461	0.95
238_Y	243_F	1.458	0.95
197_V	516_I	1.439	0.94
195_A	241_A	1.430	0.94
518_V	522_F	1.428	0.94
429_W	506_A	1.418	0.94
229_G	261_L	1.400	0.94
264_F	268_W	1.397	0.94
118_I	229_G	1.395	0.93
197_V	520_Y	1.392	0.93
134_F	437_S	1.385	0.93
103_D	289_Y	1.369	0.93
274_L	277_R	1.361	0.93
192_S	242_S	1.360	0.93
88_I	304_L	1.357	0.93
419_A	422_I	1.340	0.92
87_T	358_W	1.338	0.92
164_N	476_P	1.330	0.92
157_Q	501_K	1.327	0.92
18_A	21_T	1.324	0.92
504_P	508_G	1.316	0.91
224_P	267_V	1.316	0.91
422_I	511_I	1.316	0.91
90_N	379_S	1.312	0.91
53_T	60_I	1.311	0.91
486_V	498_V	1.300	0.91
236_G	253_G	1.293	0.91
128_F	136_Y	1.289	0.90
180_A	187_L	1.289	0.90
224_P	270_P	1.284	0.90
179_L	190_I	1.282	0.90
93_V	99_D	1.282	0.90
69_I	402_F	1.281	0.90
135_G	170_G	1.276	0.90
482_A	499_I	1.273	0.90
204_L	508_G	1.270	0.90
446_G	450_V	1.269	0.90
473_L	509_I	1.263	0.90
17_L	21_T	1.243	0.89
180_A	185_L	1.239	0.89
238_Y	242_S	1.236	0.88
54_F	57_G	1.234	0.88
121_A	125_G	1.229	0.88
317_P	321_F	1.212	0.87
299_S	302_I	1.212	0.87
225_I	264_F	1.205	0.87
171_A	174_T	1.196	0.87
66_A	69_I	1.194	0.87
21_T	47_I	1.192	0.87
146_I	491_Y	1.188	0.86
207_W	227_I	1.182	0.86
116_Q	148_L	1.181	0.86
174_T	177_I	1.177	0.86
44_G	396_L	1.174	0.86
243_F	459_P	1.172	0.86
121_A	162_A	1.163	0.85
157_Q	498_V	1.161	0.85
168_S	438_N	1.159	0.85
236_G	252_T	1.157	0.85
54_F	60_I	1.152	0.85
153_L	501_K	1.152	0.85
333_S	336_H	1.151	0.85
195_A	242_S	1.150	0.85
207_W	223_W	1.149	0.84
121_A	194_V	1.147	0.84
198_V	237_Q	1.145	0.84
201_L	512_Y	1.136	0.84
197_V	469_V	1.133	0.84
113_A	150_F	1.132	0.84
185_L	461_G	1.126	0.83
416_L	419_A	1.122	0.83
123_S	258_F	1.118	0.83
118_I	226_A	1.118	0.83
43_I	46_I	1.115	0.83
120_L	141_I	1.114	0.83
153_L	302_I	1.113	0.83
367_A	371_I	1.112	0.82
64_S	67_W	1.109	0.82
427_F	448_F	1.107	0.82
211_Y	219_I	1.103	0.82
307_V	357_S	1.101	0.82
511_I	514_I	1.098	0.82
84_W	376_I	1.097	0.82
117_A	213_V	1.091	0.81
433_A	502_N	1.079	0.81
76_W	354_I	1.078	0.80
90_N	378_R	1.066	0.80
72_L	343_F	1.058	0.79
136_Y	496_G	1.056	0.79
334_L	337_K	1.056	0.79
275_S	278_S	1.056	0.79
208_I	505_W	1.056	0.79
42_L	388_L	1.055	0.79
111_N	273_V	1.053	0.79
246_P	261_L	1.053	0.79
80_W	352_T	1.052	0.79
214_D	219_I	1.050	0.79
394_V	448_F	1.047	0.78
113_A	276_L	1.046	0.78
356_V	360_I	1.044	0.78
66_A	402_F	1.041	0.78
95_T	365_L	1.039	0.78
477_V	503_L	1.033	0.78
81_I	171_A	1.032	0.77
95_T	172_L	1.030	0.77
431_G	441_T	1.029	0.77
233_Y	250_D	1.029	0.77
400_F	405_M	1.028	0.77
183_T	464_P	1.023	0.77
362_S	366_R	1.022	0.77
50_L	57_G	1.021	0.77
375_A	378_R	1.020	0.77
447_A	450_V	1.014	0.76
223_W	226_A	1.013	0.76
422_I	518_V	1.013	0.76
303_V	357_S	1.011	0.76
73_V	398_Y	1.011	0.76
25_A	44_G	1.010	0.76
239_P	512_Y	1.009	0.76
24_I	337_K	1.008	0.76
100_A	289_Y	1.003	0.75
189_F	461_G	0.998	0.75
56_W	408_S	0.998	0.75
49_I	53_T	0.998	0.75
126_A	166_P	0.994	0.75
370_R	511_I	0.992	0.75
71_A	395_G	0.992	0.75
143_P	412_K	0.992	0.75
420_F	456_T	0.989	0.74
442_N	468_S	0.989	0.74
453_A	476_P	0.982	0.74
382_Q	386_G	0.982	0.74
81_I	174_T	0.980	0.74
182_V	185_L	0.973	0.73
224_P	264_F	0.972	0.73
69_I	398_Y	0.969	0.73
65_Y	68_L	0.964	0.72
178_I	181_S	0.964	0.72
196_K	520_Y	0.963	0.72
264_F	267_V	0.959	0.72
199_A	234_I	0.956	0.72
475_K	480_Q	0.955	0.72
66_A	426_L	0.951	0.71
67_W	399_V	0.949	0.71
176_I	190_I	0.947	0.71
91_T	375_A	0.947	0.71
134_F	171_A	0.943	0.71
411_W	455_L	0.943	0.71
134_F	439_T	0.942	0.71
100_A	293_D	0.940	0.71
127_L	131_L	0.939	0.70
231_L	359_I	0.939	0.70
178_I	409_L	0.936	0.70
421_I	456_T	0.930	0.70
87_T	372_M	0.929	0.70
164_N	438_N	0.928	0.70
165_A	250_D	0.927	0.69
167_V	476_P	0.925	0.69
310_L	318_L	0.924	0.69
376_I	380_F	0.922	0.69
45_S	132_V	0.922	0.69
426_L	507_I	0.922	0.69
35_I	43_I	0.918	0.69
157_Q	502_N	0.917	0.69
407_Y	451_T	0.916	0.69
51_V	56_W	0.915	0.68
120_L	148_L	0.908	0.68
190_I	464_P	0.908	0.68
26_L	44_G	0.906	0.68
283_G	511_I	0.906	0.68
325_T	344_A	0.906	0.68
231_L	235_L	0.905	0.68
497_I	500_R	0.903	0.67
187_L	191_S	0.902	0.67
15_T	55_V	0.901	0.67
456_T	463_P	0.898	0.67
504_P	507_I	0.896	0.67
96_G	155_A	0.895	0.67
83_F	380_F	0.895	0.67
162_A	209_L	0.892	0.66
358_W	372_M	0.886	0.66
401_N	440_S	0.881	0.65
20_L	24_I	0.881	0.65
127_L	305_I	0.880	0.65
299_S	303_V	0.880	0.65
191_S	246_P	0.879	0.65
118_I	261_L	0.879	0.65
246_P	249_P	0.878	0.65
303_V	360_I	0.875	0.65
64_S	515_L	0.875	0.65
160_A	476_P	0.874	0.65
116_Q	150_F	0.874	0.65
280_Q	283_G	0.873	0.65
178_I	443_A	0.869	0.64
116_Q	386_G	0.864	0.64
54_F	330_A	0.863	0.64
361_I	367_A	0.861	0.64
47_I	50_L	0.861	0.64
470_G	474_A	0.860	0.64
275_S	279_V	0.860	0.64
228_L	260_I	0.857	0.63
226_A	231_L	0.855	0.63
332_S	342_S	0.854	0.63
214_D	220_R	0.852	0.63
20_L	409_L	0.852	0.63
27_L	195_A	0.851	0.63
429_W	510_L	0.849	0.63
237_Q	438_N	0.845	0.62
14_L	55_V	0.845	0.62
121_A	230_S	0.844	0.62
410_A	451_T	0.842	0.62
497_I	501_K	0.841	0.62
192_S	238_Y	0.838	0.62
145_L	212_L	0.837	0.61
215_K	408_S	0.835	0.61
63_V	72_L	0.834	0.61
290_S	511_I	0.833	0.61
203_L	231_L	0.832	0.61
188_L	191_S	0.831	0.61
164_N	472_E	0.830	0.61
79_S	390_G	0.827	0.61
168_S	472_E	0.825	0.60
475_K	484_A	0.824	0.60
484_A	505_W	0.823	0.60
59_P	223_W	0.823	0.60
155_A	298_L	0.823	0.60
129_E	170_G	0.822	0.60
230_S	234_I	0.820	0.60
428_G	445_F	0.819	0.60
80_W	351_G	0.818	0.60
210_L	226_A	0.817	0.60
308_V	311_W	0.815	0.59
128_F	140_F	0.815	0.59
266_R	281_P	0.813	0.59
178_I	434_L	0.812	0.59
335_L	341_V	0.811	0.59
296_E	299_S	0.811	0.59
331_Y	335_L	0.807	0.59
226_A	230_S	0.807	0.59
190_I	450_V	0.806	0.59
115_V	222_A	0.806	0.59
363_L	369_P	0.804	0.58
200_I	516_I	0.803	0.58
90_N	375_A	0.801	0.58
128_F	397_A	0.798	0.58
29_L	301_F	0.798	0.58
467_N	475_K	0.797	0.58
26_L	144_L	0.794	0.57
287_K	291_T	0.791	0.57
34_R	497_I	0.789	0.57
30_L	34_R	0.785	0.57
302_I	306_I	0.785	0.57
315_W	318_L	0.784	0.56
176_I	468_S	0.783	0.56
431_G	445_F	0.783	0.56
126_A	162_A	0.782	0.56
129_E	135_G	0.781	0.56
127_L	304_L	0.780	0.56
370_R	373_G	0.779	0.56
507_I	511_I	0.777	0.56
115_V	455_L	0.775	0.56
101_F	298_L	0.774	0.55
18_A	51_V	0.767	0.55
197_V	200_I	0.763	0.54
369_P	374_E	0.761	0.54
57_G	359_I	0.761	0.54
378_R	381_H	0.759	0.54
86_L	101_F	0.758	0.54
244_I	252_T	0.758	0.54
179_L	443_A	0.757	0.54
240_V	256_I	0.755	0.54
24_I	28_I	0.754	0.54
409_L	434_L	0.753	0.53
191_S	314_P	0.751	0.53
173_G	245_G	0.750	0.53
327_S	342_S	0.749	0.53
127_L	246_P	0.746	0.53
511_I	519_L	0.745	0.53
478_A	483_S	0.745	0.53
182_V	443_A	0.743	0.52
150_F	421_I	0.743	0.52
132_V	136_Y	0.742	0.52
199_A	238_Y	0.741	0.52
171_A	176_I	0.739	0.52
133_G	170_G	0.738	0.52
176_I	442_N	0.737	0.52
369_P	422_I	0.736	0.52
259_V	271_K	0.735	0.52
78_I	134_F	0.735	0.52
185_L	464_P	0.733	0.51
125_G	209_L	0.733	0.51
127_L	482_A	0.730	0.51
321_F	364_V	0.727	0.51
371_I	374_E	0.727	0.51
437_S	440_S	0.727	0.51
75_T	389_T	0.726	0.51
263_L	288_K	0.725	0.51
39_L	315_W	0.724	0.51
141_I	253_G	0.724	0.51
421_I	514_I	0.722	0.50
416_L	423_V	0.721	0.50
470_G	477_V	0.720	0.50
120_L	124_L	0.717	0.50
472_E	480_Q	0.717	0.50
283_G	286_S	0.715	0.50
95_T	427_F	0.714	0.50
81_I	88_I	0.711	0.49
479_P	483_S	0.710	0.49
50_L	61_I	0.710	0.49
43_I	447_A	0.707	0.49
388_L	392_F	0.706	0.49
45_S	399_V	0.705	0.49
136_Y	405_M	0.704	0.49
102_R	144_L	0.702	0.48
420_F	502_N	0.702	0.48
131_L	171_A	0.702	0.48
34_R	40_A	0.701	0.48
136_Y	439_T	0.700	0.48
182_V	446_G	0.700	0.48
285_E	340_G	0.699	0.48
162_A	166_P	0.699	0.48
438_N	475_K	0.699	0.48
84_W	355_L	0.699	0.48
253_G	303_V	0.698	0.48
217_R	220_R	0.698	0.48
232_S	236_G	0.696	0.48
75_T	391_I	0.695	0.48
116_Q	414_S	0.693	0.48
468_S	472_E	0.692	0.47
308_V	354_I	0.692	0.47
166_P	438_N	0.690	0.47
118_I	218_G	0.689	0.47
31_A	117_A	0.688	0.47
84_W	179_L	0.688	0.47
239_P	283_G	0.687	0.47
287_K	377_K	0.684	0.47
469_V	520_Y	0.683	0.47
119_V	265_L	0.682	0.46
47_I	51_V	0.681	0.46
208_I	457_G	0.680	0.46
207_W	456_T	0.679	0.46
311_W	316_S	0.679	0.46
395_G	444_L	0.678	0.46
168_S	237_Q	0.674	0.46
53_T	64_S	0.673	0.46
47_I	412_K	0.672	0.45
193_S	462_L	0.671	0.45
438_N	469_V	0.671	0.45
156_L	448_F	0.668	0.45
168_S	176_I	0.668	0.45
84_W	354_I	0.665	0.45
53_T	259_V	0.664	0.45
122_W	249_P	0.663	0.45
164_N	167_V	0.662	0.45
43_I	284_G	0.662	0.45
421_I	518_V	0.662	0.45
232_S	477_V	0.661	0.44
259_V	302_I	0.660	0.44
93_V	102_R	0.660	0.44
130_G	514_I	0.660	0.44
406_A	443_A	0.659	0.44
206_P	467_N	0.659	0.44
62_Q	66_A	0.659	0.44
404_G	519_L	0.659	0.44
198_V	202_A	0.657	0.44
397_A	440_S	0.656	0.44
67_W	395_G	0.656	0.44
101_F	405_M	0.656	0.44
45_S	49_I	0.656	0.44
412_K	415_D	0.655	0.44
24_I	64_S	0.655	0.44
102_R	470_G	0.655	0.44
165_A	472_E	0.653	0.44
151_D	154_K	0.653	0.44
287_K	360_I	0.653	0.44
503_L	508_G	0.652	0.44
285_E	306_I	0.651	0.43
44_G	86_L	0.651	0.43
286_S	494_K	0.649	0.43
381_H	511_I	0.649	0.43
260_I	380_F	0.649	0.43
180_A	190_I	0.649	0.43
390_G	481_T	0.648	0.43
211_Y	216_W	0.646	0.43
321_F	326_L	0.645	0.43
178_I	182_V	0.645	0.43
48_T	399_V	0.644	0.43
438_N	472_E	0.644	0.43
171_A	437_S	0.643	0.43
78_I	178_I	0.643	0.43
278_S	494_K	0.643	0.43
312_T	315_W	0.640	0.42
303_V	356_V	0.638	0.42
23_I	130_G	0.638	0.42
238_Y	516_I	0.637	0.42
168_S	468_S	0.637	0.42
122_W	253_G	0.635	0.42
306_I	373_G	0.634	0.42
148_L	465_A	0.632	0.42
56_W	298_L	0.631	0.42
237_Q	472_E	0.631	0.42
203_L	315_W	0.631	0.42
130_G	164_N	0.630	0.41
253_G	307_V	0.630	0.41
158_V	347_P	0.629	0.41
189_F	193_S	0.629	0.41
390_G	484_A	0.628	0.41
169_F	249_P	0.628	0.41
422_I	425_P	0.628	0.41
281_P	285_E	0.628	0.41
81_I	255_L	0.627	0.41
113_A	274_L	0.626	0.41
52_A	399_V	0.626	0.41
384_W	388_L	0.625	0.41
127_L	354_I	0.624	0.41
304_L	396_L	0.623	0.41
91_T	367_A	0.622	0.41
284_G	295_I	0.621	0.41
304_L	352_T	0.621	0.41
331_Y	334_L	0.619	0.40
29_L	32_G	0.618	0.40
111_N	254_S	0.618	0.40
256_I	260_I	0.618	0.40
289_Y	294_V	0.617	0.40
406_A	434_L	0.617	0.40
266_R	288_K	0.616	0.40
326_L	348_F	0.616	0.40
301_F	354_I	0.616	0.40
330_A	356_V	0.614	0.40
221_E	224_P	0.611	0.40
158_V	502_N	0.610	0.40
29_L	232_S	0.609	0.39
425_P	479_P	0.609	0.39
41_T	393_V	0.609	0.39
441_T	472_E	0.607	0.39
113_A	275_S	0.606	0.39
368_S	454_R	0.605	0.39
302_I	511_I	0.605	0.39
172_L	484_A	0.604	0.39
203_L	461_G	0.603	0.39
385_G	388_L	0.600	0.39
34_R	99_D	0.600	0.39
163_N	480_Q	0.600	0.39
60_I	259_V	0.600	0.39
85_G	132_V	0.599	0.39
354_I	479_P	0.599	0.39
123_S	126_A	0.598	0.38
199_A	250_D	0.598	0.38
166_P	194_V	0.598	0.38
53_T	384_W	0.597	0.38
138_W	485_G	0.596	0.38
95_T	464_P	0.596	0.38
373_G	381_H	0.596	0.38
263_L	286_S	0.596	0.38
105_I	474_A	0.596	0.38
125_G	163_N	0.595	0.38
125_G	165_A	0.595	0.38
188_L	192_S	0.595	0.38
238_Y	250_D	0.595	0.38
172_L	443_A	0.595	0.38
512_Y	516_I	0.594	0.38
38_W	385_G	0.593	0.38
184_G	320_K	0.592	0.38
223_W	290_S	0.592	0.38
117_A	121_A	0.591	0.38
359_I	518_V	0.591	0.38
460_V	518_V	0.591	0.38
173_G	198_V	0.591	0.38
288_K	515_L	0.589	0.38
183_T	186_P	0.589	0.38
36_T	39_L	0.588	0.37
303_V	364_V	0.588	0.37
200_I	469_V	0.587	0.37
55_V	68_L	0.587	0.37
31_A	496_G	0.586	0.37
21_T	364_V	0.586	0.37
136_Y	175_P	0.584	0.37
18_A	176_I	0.583	0.37
480_Q	484_A	0.583	0.37
413_T	416_L	0.582	0.37
103_D	287_K	0.582	0.37
191_S	389_T	0.581	0.37
409_L	484_A	0.581	0.37
60_I	267_V	0.580	0.37
111_N	269_R	0.579	0.37
101_F	297_A	0.579	0.37
41_T	161_L	0.578	0.37
231_L	342_S	0.578	0.37
310_L	423_V	0.577	0.36
60_I	306_I	0.577	0.36
204_L	512_Y	0.576	0.36
235_L	281_P	0.576	0.36
60_I	368_S	0.575	0.36
274_L	278_S	0.575	0.36
281_P	325_T	0.575	0.36
193_S	196_K	0.574	0.36
435_S	444_L	0.574	0.36
175_P	481_T	0.574	0.36
153_L	157_Q	0.573	0.36
384_W	474_A	0.573	0.36
130_G	298_L	0.572	0.36
46_I	189_F	0.570	0.36
253_G	469_V	0.569	0.36
138_W	439_T	0.569	0.36
249_P	253_G	0.569	0.36
88_I	361_I	0.569	0.36
114_R	206_P	0.569	0.36
17_L	368_S	0.568	0.36
284_G	366_R	0.567	0.36
453_A	458_L	0.567	0.36
126_A	432_C	0.567	0.36
292_K	306_I	0.567	0.36
229_G	232_S	0.566	0.35
417_G	456_T	0.564	0.35
34_R	93_V	0.563	0.35
19_S	233_Y	0.562	0.35
368_S	373_G	0.561	0.35
114_R	221_E	0.561	0.35
182_V	394_V	0.561	0.35
212_L	441_T	0.561	0.35
26_L	82_V	0.560	0.35
280_Q	291_T	0.560	0.35
46_I	71_A	0.560	0.35
440_S	443_A	0.558	0.35
67_W	453_A	0.557	0.35
456_T	518_V	0.557	0.35
127_L	159_S	0.557	0.35
192_S	195_A	0.556	0.35
467_N	480_Q	0.555	0.35
284_G	355_L	0.554	0.34
21_T	51_V	0.554	0.34
363_L	515_L	0.553	0.34
321_F	325_T	0.553	0.34
130_G	470_G	0.553	0.34
379_S	416_L	0.553	0.34
342_S	359_I	0.552	0.34
64_S	454_R	0.552	0.34
153_L	355_L	0.551	0.34
287_K	369_P	0.551	0.34
241_A	249_P	0.551	0.34
27_L	497_I	0.550	0.34
78_I	169_F	0.550	0.34
440_S	479_P	0.549	0.34
30_L	37_A	0.549	0.34
416_L	498_V	0.547	0.34
76_W	347_P	0.547	0.34
285_E	320_K	0.547	0.34
285_E	369_P	0.547	0.34
51_V	54_F	0.547	0.34
286_S	377_K	0.546	0.34
58_T	403_S	0.545	0.34
195_A	237_Q	0.544	0.34
167_V	439_T	0.543	0.33
131_L	174_T	0.543	0.33
476_P	491_Y	0.543	0.33
138_W	484_A	0.542	0.33
44_G	48_T	0.541	0.33
393_V	478_A	0.540	0.33
171_A	175_P	0.539	0.33
60_I	64_S	0.539	0.33
126_A	163_N	0.539	0.33
301_F	397_A	0.539	0.33
251_I	422_I	0.538	0.33
125_G	166_P	0.538	0.33
484_A	496_G	0.537	0.33
438_N	442_N	0.537	0.33
438_N	468_S	0.537	0.33
220_R	285_E	0.536	0.33
24_I	54_F	0.535	0.33
224_P	228_L	0.534	0.33
417_G	423_V	0.533	0.33
134_F	170_G	0.533	0.33
411_W	448_F	0.531	0.32
118_I	123_S	0.531	0.32
444_L	479_P	0.531	0.32
252_T	263_L	0.531	0.32
110_T	227_I	0.531	0.32
240_V	244_I	0.530	0.32
216_W	219_I	0.530	0.32
76_W	262_L	0.529	0.32
397_A	400_F	0.529	0.32
272_R	344_A	0.529	0.32
414_S	448_F	0.528	0.32
407_Y	411_W	0.527	0.32
17_L	24_I	0.527	0.32
24_I	272_R	0.527	0.32
46_I	377_K	0.527	0.32
278_S	281_P	0.527	0.32
24_I	227_I	0.527	0.32
105_I	386_G	0.527	0.32
121_A	473_L	0.526	0.32
127_L	208_I	0.525	0.32
131_L	158_V	0.525	0.32
87_T	376_I	0.524	0.32
34_R	161_L	0.524	0.32
219_I	274_L	0.522	0.32
46_I	145_L	0.522	0.32
50_L	285_E	0.519	0.31
503_L	507_I	0.519	0.31
406_A	483_S	0.518	0.31
72_L	326_L	0.518	0.31
282_N	285_E	0.516	0.31
370_R	415_D	0.515	0.31
26_L	89_Y	0.514	0.31
438_N	476_P	0.513	0.31
265_L	268_W	0.512	0.31
14_L	23_I	0.512	0.31
330_A	410_A	0.512	0.31
130_G	308_V	0.512	0.31
85_G	124_L	0.511	0.31
170_G	437_S	0.510	0.31
135_G	351_G	0.509	0.31
47_I	286_S	0.509	0.31
359_I	362_S	0.509	0.31
199_A	202_A	0.508	0.30
200_I	451_T	0.508	0.30
122_W	236_G	0.507	0.30
247_Y	350_A	0.507	0.30
135_G	160_A	0.507	0.30
23_I	433_A	0.507	0.30
161_L	502_N	0.507	0.30
467_N	484_A	0.506	0.30
368_S	422_I	0.506	0.30
66_A	71_A	0.506	0.30
46_I	292_K	0.506	0.30
163_N	475_K	0.505	0.30
136_Y	349_V	0.505	0.30
68_L	363_L	0.504	0.30
83_F	87_T	0.504	0.30
196_K	241_A	0.503	0.30
49_I	64_S	0.502	0.30
275_S	280_Q	0.502	0.30
86_L	354_I	0.502	0.30
166_P	206_P	0.502	0.30
337_K	447_A	0.502	0.30
330_A	333_S	0.501	0.30
214_D	485_G	0.501	0.30
56_W	382_Q	0.501	0.30
27_L	51_V	0.501	0.30
140_F	212_L	0.500	0.30
285_E	368_S	0.500	0.30
123_S	229_G	0.500	0.30
397_A	406_A	0.500	0.30
460_V	519_L	0.500	0.30
269_R	355_L	0.500	0.30

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4r0cA	3	0.8491	99.7	0.873	Contact Map
4f35D	2	0.7491	99.7	0.874	Contact Map
4r1iA	2	0.8528	99.6	0.881	Contact Map
3qe7A	2	0.4792	22.8	0.979	Contact Map
3s8fA	1	0.5792	20.9	0.979	Contact Map
3qnqA	2	0.5151	19.8	0.979	Contact Map
2m67A	1	0.1377	12.8	0.981	Contact Map
4x5mA	2	0.1698	10.8	0.982	Contact Map
1p22C	1	0.0208	8.1	0.983	Contact Map
2m20A	2	0.0943	6.4	0.983	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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