GREMLIN Database
Q7LX70 - Pyruvate synthase delta chain (Pyruvic-ferredoxin oxidoreductase delta chain) (PorD-like)
UniProt: Q7LX70 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 363 (313)
Sequences: 1291 (820)
Seq/√Len: 46.4

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
192_K196_N6.2311.00
143_T211_Y5.6871.00
39_R66_D4.0531.00
116_S141_N3.6051.00
151_P155_G3.5301.00
266_D269_T3.3841.00
196_N200_S3.3211.00
87_V121_L3.1731.00
114_L142_W3.1181.00
86_D115_K3.0861.00
338_K341_Y2.9961.00
128_I210_D2.9811.00
328_R331_Y2.7271.00
264_T319_V2.6831.00
187_K191_K2.6671.00
155_G204_E2.6141.00
236_L239_T2.5871.00
264_T324_F2.5491.00
36_E188_Y2.5471.00
114_L118_G2.5431.00
231_T234_E2.4631.00
120_M144_L2.4271.00
119_T143_T2.4221.00
258_T301_V2.3861.00
331_Y334_W2.3751.00
262_R297_Y2.2761.00
266_D317_V2.2271.00
112_L231_T2.2101.00
216_K219_G2.1021.00
204_E207_S2.0320.99
148_K151_P2.0200.99
249_R252_L1.9820.99
164_T168_V1.9350.99
12_I15_R1.9310.99
125_T148_K1.9270.99
122_V144_L1.9210.99
184_H187_K1.9200.99
144_L212_R1.8930.99
91_L164_T1.8870.99
184_H188_Y1.8860.99
96_L139_D1.8750.99
284_C296_A1.8720.99
196_N199_V1.8710.99
127_R130_E1.8620.99
117_N141_N1.8570.99
312_V315_C1.8170.99
339_A342_K1.8140.99
119_T175_L1.8010.99
154_S261_E1.7670.98
284_C301_V1.7390.98
331_Y335_K1.7030.98
332_E336_E1.6950.98
110_I139_D1.6870.98
305_I308_E1.6760.98
29_G189_V1.6750.98
193_Q197_K1.6640.98
284_C295_I1.6570.98
90_V120_M1.6430.98
190_T203_R1.6380.97
11_E14_Y1.6370.97
341_Y344_W1.6100.97
170_G205_A1.6060.97
321_E325_T1.5920.97
28_E189_V1.5500.96
257_T298_D1.5240.96
338_K342_K1.5230.96
149_T153_F1.4900.96
128_I213_T1.4900.96
29_G166_E1.4840.95
174_K182_L1.4780.95
269_T315_C1.4750.95
288_T291_G1.4620.95
330_P333_M1.4520.95
337_D340_K1.4450.95
332_E335_K1.4340.94
156_L197_K1.4310.94
93_D124_S1.4060.94
146_V210_D1.4050.94
307_A317_V1.3990.94
150_E260_F1.3970.94
109_P112_L1.3940.94
343_E346_K1.3860.93
333_M338_K1.3860.93
235_M239_T1.3810.93
328_R332_E1.3760.93
342_K345_L1.3620.93
341_Y346_K1.3590.93
337_D341_Y1.3490.92
30_I43_S1.3470.92
15_R92_D1.3400.92
40_P73_L1.3290.92
333_M336_E1.3220.92
331_Y337_D1.3170.92
166_E189_V1.3150.91
128_I146_V1.3140.91
305_I309_V1.2950.91
146_V212_R1.2940.91
110_I113_K1.2900.91
130_E134_M1.2830.90
170_G206_Y1.2740.90
296_A332_E1.2720.90
112_L234_E1.2640.90
182_L206_Y1.2570.89
340_K343_E1.2420.89
307_A318_M1.2380.89
335_K338_K1.2150.88
10_V14_Y1.2060.87
279_Y305_I1.2060.87
46_R59_K1.1970.87
334_W337_D1.1910.87
332_E338_K1.1890.87
19_Q54_N1.1780.86
93_D125_T1.1660.86
330_P334_W1.1590.85
342_K346_K1.1520.85
339_A344_W1.1450.85
85_V88_I1.1410.84
124_S131_L1.1380.84
269_T313_K1.1340.84
46_R233_Q1.1330.84
336_E340_K1.1290.84
341_Y345_L1.0980.82
28_E121_L1.0970.82
193_Q196_N1.0950.82
178_D182_L1.0910.82
19_Q29_G1.0830.81
85_V113_K1.0830.81
11_E113_K1.0780.81
124_S146_V1.0760.81
296_A336_E1.0760.81
11_E15_R1.0730.80
269_T312_V1.0690.80
188_Y191_K1.0620.80
10_V15_R1.0610.80
327_Y330_P1.0600.80
333_M337_D1.0570.79
319_V324_F1.0570.79
337_D342_K1.0550.79
264_T317_V1.0490.79
186_L206_Y1.0360.78
331_Y338_K1.0340.78
171_G205_A1.0310.78
340_K345_L1.0290.78
331_Y336_E1.0290.78
90_V110_I1.0290.78
204_E208_S1.0290.78
131_L146_V1.0280.78
321_E324_F1.0280.78
329_R332_E1.0270.77
330_P337_D1.0230.77
338_K343_E1.0200.77
143_T213_T1.0180.77
200_S204_E1.0170.77
82_P85_V1.0130.76
186_L203_R1.0110.76
46_R81_E1.0100.76
182_L186_L1.0050.76
329_R333_M0.9980.75
156_L167_K0.9960.75
335_K340_K0.9950.75
332_E337_D0.9920.75
271_I275_L0.9910.75
338_K344_W0.9900.75
340_K344_W0.9900.75
264_T323_M0.9810.74
111_N114_L0.9810.74
236_L240_V0.9790.74
334_W340_K0.9780.74
110_I120_M0.9770.74
158_A197_K0.9730.73
28_E87_V0.9720.73
132_L217_G0.9670.73
145_G211_Y0.9660.73
340_K346_K0.9500.72
29_G89_I0.9460.71
287_E291_G0.9430.71
334_W341_Y0.9330.70
279_Y309_V0.9220.69
186_L190_T0.9180.69
333_M340_K0.9130.69
338_K346_K0.9130.69
126_K134_M0.9120.69
192_K199_V0.9100.68
334_W338_K0.9050.68
27_A47_Y0.9040.68
8_K179_I0.9020.68
335_K339_A0.8970.67
152_S167_K0.8840.66
331_Y340_K0.8810.66
335_K342_K0.8790.66
338_K345_L0.8790.66
9_Y82_P0.8770.65
109_P231_T0.8760.65
152_S171_G0.8720.65
41_A227_P0.8670.65
152_S208_S0.8670.65
319_V323_M0.8660.65
152_S204_E0.8630.64
294_D331_Y0.8610.64
57_P99_V0.8570.64
336_E339_A0.8460.63
88_I110_I0.8410.62
13_V57_P0.8330.61
240_V274_K0.8320.61
43_S168_V0.8280.61
159_F163_L0.8280.61
84_L115_K0.8270.61
176_R180_I0.8220.60
151_P210_D0.8210.60
57_P230_L0.8140.60
28_E166_E0.8130.60
259_K263_P0.8120.59
127_R148_K0.8020.59
174_K209_V0.8000.58
216_K220_I0.7990.58
19_Q55_G0.7980.58
263_P318_M0.7940.58
337_D343_E0.7920.58
46_R230_L0.7910.57
170_G182_L0.7900.57
287_E290_D0.7880.57
93_D126_K0.7870.57
215_M218_E0.7870.57
121_L175_L0.7860.57
288_T339_A0.7840.57
128_I132_L0.7840.57
307_A316_I0.7820.57
97_K134_M0.7750.56
128_I212_R0.7700.55
170_G186_L0.7690.55
89_I156_L0.7660.55
294_D328_R0.7640.55
271_I284_C0.7620.55
10_V13_V0.7590.54
93_D134_M0.7590.54
138_K283_E0.7550.54
296_A321_E0.7540.54
336_E341_Y0.7510.54
325_T329_R0.7500.53
339_A345_L0.7470.53
137_K221_D0.7450.53
337_D346_K0.7430.53
332_E339_A0.7420.53
27_A31_V0.7350.52
150_E164_T0.7350.52
339_A343_E0.7330.52
328_R333_M0.7320.52
113_K168_V0.7300.52
292_Y321_E0.7260.51
121_L171_G0.7220.51
325_T328_R0.7210.51
92_D150_E0.7180.50
36_E184_H0.7150.50
92_D164_T0.7120.50
274_K293_Y0.7100.50
96_L110_I0.7100.50
11_E86_D0.7080.49
214_V217_G0.7070.49
194_D197_K0.7040.49
127_R131_L0.7030.49
327_Y333_M0.7020.49
176_R179_I0.7020.49
13_V113_K0.6990.48
29_G87_V0.6980.48
257_T321_E0.6940.48
57_P228_R0.6930.48
164_T189_V0.6920.48
41_A46_R0.6920.48
9_Y84_L0.6910.48
133_K219_G0.6890.47
34_A41_A0.6890.47
137_K140_F0.6820.47
26_I64_I0.6820.47
99_V230_L0.6810.47
34_A52_E0.6800.47
73_L77_S0.6790.46
321_E336_E0.6750.46
77_S294_D0.6740.46
339_A346_K0.6730.46
262_R321_E0.6720.46
255_R258_T0.6720.46
22_L26_I0.6700.46
94_T98_G0.6700.46
82_P285_F0.6690.45
284_C332_E0.6690.45
116_S143_T0.6680.45
140_F218_E0.6670.45
332_E340_K0.6660.45
330_P338_K0.6660.45
327_Y331_Y0.6630.45
337_D344_W0.6630.45
89_I164_T0.6610.45
43_S59_K0.6590.45
48_G52_E0.6590.45
117_N313_K0.6570.44
297_Y321_E0.6550.44
325_T339_A0.6530.44
248_K252_L0.6500.44
44_F81_E0.6470.43
74_I80_V0.6470.43
132_L215_M0.6460.43
266_D313_K0.6430.43
328_R335_K0.6410.43
323_M334_W0.6410.43
325_T330_P0.6410.43
141_N213_T0.6410.43
186_L202_V0.6400.43
113_K116_S0.6370.42
269_T317_V0.6340.42
313_K317_V0.6330.42
34_A56_V0.6330.42
11_E142_W0.6310.42
125_T322_S0.6290.42
334_W345_L0.6270.41
110_I305_I0.6260.41
294_D334_W0.6260.41
156_L180_I0.6230.41
193_Q200_S0.6220.41
333_M344_W0.6220.41
292_Y331_Y0.6200.41
330_P336_E0.6180.41
202_V296_A0.6160.40
268_D317_V0.6150.40
235_M240_V0.6130.40
24_K195_A0.6110.40
255_R299_Y0.6090.40
327_Y340_K0.6070.40
320_D323_M0.6050.39
26_I29_G0.6030.39
93_D148_K0.6010.39
271_I312_V0.5980.39
11_E115_K0.5970.39
52_E254_K0.5950.38
128_I131_L0.5950.38
239_T242_P0.5930.38
34_A37_M0.5920.38
170_G189_V0.5910.38
255_R259_K0.5910.38
139_D147_I0.5910.38
166_E275_L0.5880.38
156_L205_A0.5880.38
132_L140_F0.5870.38
241_I248_K0.5870.38
336_E345_L0.5870.38
205_A208_S0.5860.38
264_T267_F0.5850.37
121_L189_V0.5850.37
214_V218_E0.5850.37
156_L186_L0.5840.37
261_E307_A0.5840.37
278_V309_V0.5840.37
22_L89_I0.5810.37
45_G60_Y0.5810.37
87_V171_G0.5800.37
156_L200_S0.5800.37
22_L172_L0.5790.37
284_C292_Y0.5780.37
29_G121_L0.5770.37
243_A246_R0.5760.37
127_R217_G0.5750.37
87_V164_T0.5750.37
245_P248_K0.5750.37
192_K290_D0.5740.36
174_K207_S0.5730.36
88_I96_L0.5720.36
179_I202_V0.5700.36
130_E133_K0.5690.36
41_A54_N0.5690.36
124_S130_E0.5690.36
85_V91_L0.5680.36
59_K230_L0.5680.36
200_S203_R0.5640.36
96_L135_I0.5620.35
296_A301_V0.5590.35
205_A228_R0.5580.35
285_F295_I0.5570.35
288_T338_K0.5550.35
148_K230_L0.5550.35
266_D323_M0.5550.35
26_I89_I0.5540.35
171_G209_V0.5520.34
249_R253_F0.5510.34
127_R212_R0.5510.34
84_L98_G0.5500.34
152_S158_A0.5490.34
273_C276_C0.5490.34
271_I297_Y0.5480.34
330_P340_K0.5480.34
137_K215_M0.5460.34
324_F327_Y0.5460.34
283_E295_I0.5440.34
92_D277_W0.5440.34
173_A195_A0.5430.34
141_N155_G0.5420.34
129_N154_S0.5420.34
266_D312_V0.5410.33
199_V204_E0.5410.33
21_R25_Y0.5400.33
67_G73_L0.5390.33
220_I329_R0.5370.33
332_E342_K0.5360.33
275_L312_V0.5360.33
240_V246_R0.5360.33
148_K278_V0.5350.33
326_D330_P0.5350.33
159_F165_M0.5340.33
186_L330_P0.5330.33
30_I41_A0.5330.33
51_P302_G0.5320.33
54_N113_K0.5310.33
77_S246_R0.5300.33
197_K202_V0.5300.33
9_Y294_D0.5290.32
257_T296_A0.5280.32
176_R271_I0.5280.32
33_T283_E0.5280.32
80_V272_K0.5260.32
165_M173_A0.5260.32
33_T37_M0.5250.32
331_Y339_A0.5250.32
133_K217_G0.5240.32
202_V208_S0.5240.32
330_P335_K0.5230.32
83_D328_R0.5210.32
43_S90_V0.5210.32
89_I172_L0.5210.32
312_V317_V0.5200.32
36_E39_R0.5180.31
296_A329_R0.5180.31
167_K295_I0.5170.31
334_W339_A0.5170.31
9_Y83_D0.5170.31
246_R284_C0.5170.31
148_K245_P0.5160.31
298_D321_E0.5150.31
26_I60_Y0.5150.31
121_L166_E0.5130.31
155_G196_N0.5130.31
149_T312_V0.5130.31
120_M145_G0.5120.31
331_Y342_K0.5120.31
53_R58_A0.5120.31
328_R334_W0.5120.31
323_M327_Y0.5110.31
202_V292_Y0.5110.31
269_T316_I0.5110.31
277_W293_Y0.5110.31
67_G141_N0.5110.31
135_I144_L0.5100.31
168_V189_V0.5100.31
84_L116_S0.5090.31
156_L199_V0.5080.31
242_P278_V0.5060.30
232_W235_M0.5040.30
127_R210_D0.5040.30
335_K345_L0.5030.30
336_E344_W0.5020.30
306_C310_C0.5020.30
303_C306_C0.5020.30
300_C310_C0.5020.30
300_C306_C0.5020.30
300_C303_C0.5020.30
280_C306_C0.5020.30
303_C310_C0.5020.30
280_C310_C0.5020.30
280_C300_C0.5020.30
280_C303_C0.5020.30
152_S160_K0.5010.30
11_E59_K0.5000.30
232_W237_E0.5000.30
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2c42A 2 0.9339 100 0.434 Contact Map
5c4iB 1 0.7851 100 0.585 Contact Map
2raaA 1 0.4793 100 0.721 Contact Map
3on3A 2 0.4711 100 0.747 Contact Map
3g2eA 4 0.4959 100 0.755 Contact Map
1hfeL 2 0.3333 99.4 0.884 Contact Map
1bc6A 1 0.2011 99.4 0.888 Contact Map
1gteA 4 0.8678 99.4 0.889 Contact Map
1jnrB 1 0.2727 99.3 0.89 Contact Map
1h98A 1 0.2011 99.3 0.891 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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