Q7LX61 - SULSO - GREMLIN Contacts

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Q7LX61 - Acylaminoacyl-peptidase, putative (ApeH-2)

UniProt:	Q7LX61	Sequences: MQIQFHYMEYSELIKLLEETVRIPFYAILGKLKNNLIYLATSEGEISIYALIGGKNVKLTKSPIAISTRPKSSLDFIPFARDVEKGKEIHAIHIANLKGEEFQIESPRVRISSLTYDDKRIVFTGSSQNETSLYVIENGKLSKLTTIPPFSFVTDVNEKYIIGSGVLKGNPRSQEFFIADFSGNIEILTPKEGSVTNAYYLMGNKVYLISDYETPGESYWIYIYDIESKKYDRVEIPGFEFKAIEIYYDPEDLLIIAKKDGESRLFDNGKEINTPKGTISGATRIGDEIYFSHSSLVSPHKIYKVSRYGKIEVVVDNRKVDVGEVEYVKVKTDVEVPTWVIKRKIPGNTIIYIHGGPWSEVDNSWNLLIAPLVLAGYNVIAPNYRGSTGYGSKFMFMNIGDAGGGDLRDVVKVRDYAIETGITNKVGIMGYSYGGYMTLLAVGKEPDKWDFGIAGAAVADWVEMYDLSDSLFRGFMEILFNGKNIDLMKERSPITYVRNVKVPLCIIHSQNDTRTPLNPVMRYIQELQRTGKTYEFHVIPNLGHAIYKVSDAIDILLPALIFLKKLEEQ	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	569 (489)
Sequences:	9999 (8347)
Seq/√Len:	377.4

ECOLI - PTRB
BACSU - YUXL
HALSA - Q9HS46 Q9HN07
SULSO - Q7LX61 Q97VD6 Q97YB2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
442_V	452_G	4.532	1.00
415_D	448_K	3.942	1.00
329_K	335_E	3.673	1.00
331_K	412_K	3.194	1.00
326_E	330_V	3.162	1.00
438_T	452_G	3.146	1.00
539_I	554_D	3.139	1.00
416_Y	420_T	3.094	1.00
135_V	138_N	2.991	1.00
174_Q	178_I	2.951	1.00
324_E	342_K	2.815	1.00
416_Y	419_E	2.804	1.00
178_I	181_F	2.790	1.00
486_D	490_E	2.632	1.00
347_G	378_N	2.612	1.00
431_Y	455_G	2.569	1.00
322_V	332_T	2.568	1.00
225_D	228_S	2.500	1.00
326_E	332_T	2.473	1.00
428_I	441_A	2.424	1.00
295_S	298_S	2.401	1.00
206_V	210_S	2.392	1.00
175_E	178_I	2.339	1.00
401_D	404_G	2.312	1.00
535_E	558_P	2.306	1.00
427_G	563_L	2.296	1.00
377_Y	564_K	2.268	1.00
340_V	380_I	2.221	1.00
338_T	413_V	2.188	1.00
349_T	423_T	2.161	1.00
484_N	487_L	2.132	1.00
554_D	558_P	2.101	1.00
427_G	451_F	2.094	1.00
375_A	564_K	2.078	1.00
76_F	96_N	2.065	1.00
115_T	120_R	2.058	1.00
78_P	112_S	2.054	1.00
132_S	143_K	2.036	1.00
206_V	209_I	2.015	1.00
517_L	538_V	1.967	1.00
447_D	501_K	1.934	1.00
134_Y	137_E	1.931	1.00
95_A	101_E	1.928	1.00
453_I	563_L	1.895	1.00
414_R	426_V	1.872	1.00
288_E	304_K	1.865	1.00
341_I	373_V	1.848	1.00
489_K	495_T	1.844	1.00
207_Y	210_S	1.842	1.00
147_I	150_F	1.841	1.00
174_Q	177_F	1.839	1.00
442_V	504_L	1.839	1.00
131_T	134_Y	1.834	1.00
187_I	190_P	1.802	1.00
206_V	211_D	1.801	1.00
415_D	419_E	1.795	1.00
411_V	449_W	1.780	1.00
313_V	316_D	1.767	1.00
392_S	396_F	1.765	1.00
210_S	214_T	1.759	1.00
149_P	152_F	1.740	1.00
73_S	118_D	1.737	1.00
415_D	445_E	1.726	1.00
418_I	423_T	1.707	1.00
338_T	380_I	1.705	1.00
115_T	119_K	1.703	1.00
327_Y	335_E	1.703	1.00
327_Y	332_T	1.692	1.00
351_I	410_V	1.675	1.00
120_R	123_F	1.673	1.00
496_Y	499_N	1.672	1.00
155_D	160_Y	1.671	1.00
349_T	380_I	1.654	1.00
277_G	280_S	1.633	1.00
174_Q	181_F	1.629	1.00
194_S	197_N	1.628	1.00
500_V	523_Y	1.627	1.00
329_K	332_T	1.608	1.00
542_L	551_D	1.599	1.00
322_V	330_V	1.596	1.00
506_I	524_I	1.595	1.00
476_M	479_L	1.584	1.00
498_R	530_T	1.572	1.00
485_I	489_K	1.570	1.00
288_E	306_S	1.556	1.00
211_D	214_T	1.533	1.00
169_G	172_R	1.527	1.00
96_N	100_E	1.505	1.00
535_E	565_K	1.497	1.00
351_I	414_R	1.488	1.00
526_E	530_T	1.477	1.00
328_V	338_T	1.465	1.00
404_G	408_R	1.461	1.00
147_I	152_F	1.458	1.00
428_I	452_G	1.452	1.00
331_K	408_R	1.450	1.00
177_F	181_F	1.450	1.00
380_I	413_V	1.442	1.00
440_L	444_K	1.441	1.00
208_L	211_D	1.441	1.00
453_I	559_A	1.436	1.00
291_F	311_I	1.428	1.00
72_S	114_L	1.425	1.00
451_F	566_L	1.421	1.00
506_I	523_Y	1.419	1.00
322_V	326_E	1.414	1.00
206_V	212_Y	1.412	1.00
375_A	560_L	1.412	1.00
411_V	415_D	1.405	1.00
223_I	232_D	1.397	1.00
225_D	229_K	1.391	1.00
321_D	332_T	1.389	1.00
186_E	189_T	1.386	1.00
401_D	405_G	1.380	1.00
537_H	558_P	1.377	1.00
155_D	159_K	1.372	1.00
499_N	502_V	1.366	1.00
353_I	437_M	1.363	1.00
303_Y	313_V	1.362	1.00
221_I	224_Y	1.360	1.00
508_H	517_L	1.358	1.00
71_K	75_D	1.357	1.00
120_R	135_V	1.356	1.00
76_F	94_I	1.354	1.00
460_D	522_R	1.349	1.00
328_V	332_T	1.343	1.00
380_I	417_A	1.340	1.00
78_P	114_L	1.334	1.00
160_Y	178_I	1.332	1.00
439_L	454_A	1.324	1.00
171_P	174_Q	1.324	1.00
476_M	480_F	1.322	1.00
327_Y	330_V	1.322	1.00
485_I	488_M	1.321	1.00
321_D	330_V	1.307	1.00
218_S	222_Y	1.303	1.00
349_T	426_V	1.294	1.00
408_R	444_K	1.294	1.00
507_I	555_I	1.293	1.00
150_F	153_V	1.292	1.00
407_L	441_A	1.283	1.00
258_K	261_G	1.282	1.00
351_I	449_W	1.281	1.00
371_P	560_L	1.275	1.00
477_E	480_F	1.269	1.00
207_Y	211_D	1.267	1.00
349_T	378_N	1.266	1.00
478_I	481_N	1.266	1.00
452_G	504_L	1.265	1.00
323_G	332_T	1.256	1.00
487_L	490_E	1.254	1.00
431_Y	456_A	1.254	1.00
235_E	241_F	1.252	1.00
414_R	449_W	1.250	1.00
271_E	274_T	1.250	1.00
350_I	563_L	1.248	1.00
412_K	415_D	1.245	1.00
474_G	477_E	1.240	1.00
93_H	103_Q	1.239	1.00
404_G	490_E	1.239	1.00
328_V	382_P	1.238	1.00
402_A	461_W	1.234	1.00
342_K	378_N	1.234	1.00
70_P	77_I	1.232	1.00
526_E	529_R	1.229	1.00
517_L	521_M	1.229	1.00
406_D	433_Y	1.220	1.00
161_I	164_S	1.219	1.00
378_N	422_I	1.218	1.00
477_E	482_G	1.214	1.00
173_S	177_F	1.213	1.00
162_I	200_Y	1.211	1.00
149_P	153_V	1.210	1.00
418_I	421_G	1.210	1.00
172_R	175_E	1.206	1.00
138_N	141_L	1.200	1.00
328_V	413_V	1.200	1.00
224_Y	229_K	1.199	1.00
341_I	381_A	1.199	1.00
160_Y	164_S	1.197	1.00
442_V	502_V	1.197	1.00
411_V	448_K	1.196	1.00
425_K	450_D	1.191	1.00
115_T	118_D	1.188	1.00
393_K	397_M	1.185	1.00
385_R	409_D	1.179	1.00
326_E	329_K	1.179	1.00
452_G	502_V	1.172	1.00
146_T	149_P	1.172	1.00
209_I	214_T	1.169	1.00
148_P	151_S	1.169	1.00
521_M	538_V	1.167	1.00
287_D	307_R	1.163	1.00
208_L	214_T	1.161	1.00
197_N	200_Y	1.160	1.00
400_G	484_N	1.155	1.00
404_G	444_K	1.154	1.00
378_N	423_T	1.153	1.00
408_R	412_K	1.150	1.00
477_E	481_N	1.149	1.00
353_I	428_I	1.147	1.00
444_K	496_Y	1.135	1.00
132_S	135_V	1.134	1.00
158_E	161_I	1.126	1.00
290_Y	304_K	1.124	1.00
443_G	500_V	1.123	1.00
369_I	373_V	1.123	1.00
439_L	459_A	1.122	1.00
209_I	212_Y	1.122	1.00
561_I	565_K	1.121	1.00
443_G	523_Y	1.119	1.00
557_L	561_I	1.119	1.00
208_L	212_Y	1.118	1.00
323_G	330_V	1.118	1.00
173_S	178_I	1.117	1.00
119_K	135_V	1.114	1.00
497_V	500_V	1.110	1.00
479_L	482_G	1.099	1.00
132_S	145_T	1.092	1.00
109_V	112_S	1.091	1.00
178_I	186_E	1.090	1.00
154_T	157_N	1.089	1.00
120_R	133_L	1.087	1.00
221_I	225_D	1.087	1.00
524_I	534_Y	1.082	1.00
75_D	96_N	1.081	1.00
325_V	332_T	1.080	1.00
497_V	523_Y	1.079	1.00
454_A	506_I	1.074	1.00
171_P	175_E	1.069	1.00
210_S	213_E	1.066	1.00
301_K	313_V	1.065	1.00
418_I	426_V	1.064	1.00
134_Y	143_K	1.063	1.00
95_A	99_G	1.057	1.00
350_I	429_M	1.054	1.00
200_Y	204_N	1.047	1.00
350_I	372_L	1.047	1.00
439_L	523_Y	1.046	1.00
201_L	204_N	1.045	1.00
346_P	424_N	1.038	1.00
218_S	221_I	1.037	1.00
193_G	196_T	1.036	1.00
325_V	330_V	1.035	1.00
222_Y	225_D	1.034	1.00
453_I	505_C	1.024	1.00
134_Y	141_L	1.023	1.00
463_E	522_R	1.020	1.00
317_N	320_V	1.018	1.00
291_F	305_V	1.018	1.00
343_R	347_G	1.016	1.00
520_V	536_F	1.015	1.00
125_G	128_Q	1.014	1.00
524_I	536_F	1.012	1.00
510_Q	538_V	1.012	1.00
92_I	95_A	1.011	1.00
155_D	158_E	1.011	1.00
168_K	172_R	1.008	1.00
369_I	379_V	1.007	1.00
122_V	133_L	1.005	1.00
316_D	319_K	1.002	1.00
558_P	561_I	1.000	1.00
222_Y	233_R	0.997	1.00
429_M	455_G	0.996	1.00
360_E	389_G	0.994	1.00
351_I	380_I	0.994	1.00
98_K	104_I	0.992	1.00
476_M	481_N	0.992	1.00
72_S	118_D	0.989	1.00
462_V	489_K	0.987	1.00
264_R	271_E	0.986	1.00
147_I	151_S	0.986	1.00
220_W	223_I	0.986	1.00
486_D	489_K	0.985	1.00
528_Q	534_Y	0.983	1.00
382_P	413_V	0.983	1.00
141_L	145_T	0.982	1.00
405_G	408_R	0.982	1.00
174_Q	179_A	0.980	1.00
172_R	177_F	0.979	1.00
334_V	393_K	0.978	1.00
219_Y	223_I	0.976	1.00
247_Y	250_P	0.976	1.00
78_P	121_I	0.975	1.00
155_D	162_I	0.971	1.00
134_Y	139_G	0.970	1.00
497_V	526_E	0.970	1.00
131_T	137_E	0.967	1.00
237_P	241_F	0.965	1.00
235_E	239_F	0.965	1.00
541_N	548_K	0.965	1.00
370_A	373_V	0.963	1.00
525_Q	529_R	0.960	1.00
337_P	390_Y	0.955	1.00
262_E	266_F	0.954	1.00
220_W	224_Y	0.952	1.00
170_N	179_A	0.952	1.00
247_Y	252_D	0.951	1.00
474_G	478_I	0.949	1.00
139_G	142_S	0.948	1.00
146_T	153_V	0.948	1.00
220_W	233_R	0.944	1.00
263_S	266_F	0.942	1.00
553_I	557_L	0.942	1.00
262_E	265_L	0.939	1.00
169_G	173_S	0.938	1.00
237_P	242_K	0.936	1.00
292_S	300_H	0.931	1.00
259_K	264_R	0.930	1.00
454_A	457_A	0.929	1.00
172_R	178_I	0.929	1.00
148_P	153_V	0.928	1.00
527_L	532_K	0.925	1.00
188_L	191_K	0.924	1.00
321_D	326_E	0.923	1.00
175_E	187_I	0.920	1.00
257_A	266_F	0.919	1.00
396_F	399_I	0.918	1.00
155_D	161_I	0.917	1.00
139_G	143_K	0.916	1.00
231_Y	234_V	0.915	1.00
169_G	174_Q	0.915	1.00
175_E	181_F	0.914	1.00
205_K	225_D	0.913	1.00
123_F	141_L	0.911	1.00
132_S	137_E	0.909	1.00
257_A	261_G	0.909	1.00
78_P	92_I	0.908	1.00
142_S	145_T	0.908	1.00
117_D	120_R	0.908	1.00
436_Y	440_L	0.907	1.00
122_V	154_T	0.904	1.00
403_G	406_D	0.902	1.00
371_P	374_L	0.898	1.00
201_L	206_V	0.895	1.00
324_E	332_T	0.894	1.00
123_F	128_Q	0.893	1.00
194_S	198_A	0.893	1.00
73_S	76_F	0.892	1.00
156_V	200_Y	0.891	1.00
160_Y	163_G	0.889	1.00
196_T	200_Y	0.889	1.00
497_V	530_T	0.886	1.00
519_P	522_R	0.885	1.00
159_K	180_D	0.884	1.00
185_I	191_K	0.883	1.00
397_M	402_A	0.883	1.00
454_A	459_A	0.882	1.00
349_T	414_R	0.880	1.00
353_I	410_V	0.876	1.00
478_I	482_G	0.874	1.00
371_P	375_A	0.873	1.00
343_R	378_N	0.873	1.00
456_A	546_I	0.872	1.00
195_V	198_A	0.867	1.00
219_Y	222_Y	0.867	1.00
98_K	101_E	0.866	1.00
132_S	141_L	0.866	1.00
192_E	195_V	0.861	1.00
235_E	243_A	0.860	1.00
237_P	240_E	0.858	1.00
535_E	562_F	0.857	1.00
418_I	448_K	0.856	1.00
459_A	523_Y	0.856	1.00
94_I	121_I	0.855	1.00
287_D	306_S	0.850	1.00
458_V	461_W	0.849	1.00
235_E	238_G	0.847	1.00
138_N	143_K	0.846	1.00
127_S	130_E	0.846	1.00
207_Y	212_Y	0.843	1.00
236_I	239_F	0.842	1.00
315_V	318_R	0.842	1.00
533_T	566_L	0.840	1.00
168_K	171_P	0.837	1.00
510_Q	517_L	0.835	1.00
462_V	485_I	0.832	1.00
365_W	368_L	0.832	1.00
134_Y	138_N	0.831	1.00
114_L	121_I	0.830	1.00
207_Y	213_E	0.829	1.00
507_I	537_H	0.829	1.00
524_I	528_Q	0.828	1.00
186_E	190_P	0.828	1.00
323_G	326_E	0.828	1.00
140_K	143_K	0.826	1.00
175_E	179_A	0.826	1.00
219_Y	224_Y	0.825	1.00
171_P	179_A	0.825	1.00
301_K	315_V	0.825	1.00
537_H	540_P	0.825	1.00
94_I	114_L	0.823	1.00
506_I	520_V	0.819	1.00
255_I	261_G	0.818	1.00
340_V	378_N	0.817	1.00
158_E	163_G	0.816	1.00
504_L	532_K	0.814	1.00
135_V	141_L	0.813	1.00
326_E	342_K	0.813	1.00
146_T	151_S	0.812	1.00
384_Y	410_V	0.812	1.00
71_K	114_L	0.810	1.00
249_D	252_D	0.809	1.00
277_G	281_G	0.809	1.00
169_G	175_E	0.808	1.00
171_P	178_I	0.806	1.00
170_N	175_E	0.804	1.00
429_M	559_A	0.800	1.00
194_S	200_Y	0.799	1.00
186_E	191_K	0.798	1.00
411_V	445_E	0.798	1.00
169_G	179_A	0.797	1.00
135_V	139_G	0.796	1.00
511_N	541_N	0.795	1.00
247_Y	254_L	0.795	1.00
454_A	504_L	0.794	1.00
326_E	338_T	0.789	1.00
293_H	298_S	0.789	1.00
534_Y	537_H	0.788	1.00
484_N	488_M	0.786	1.00
340_V	422_I	0.784	1.00
112_S	121_I	0.783	1.00
170_N	173_S	0.782	1.00
314_V	317_N	0.780	1.00
443_G	496_Y	0.779	1.00
185_I	189_T	0.779	1.00
169_G	177_F	0.778	1.00
556_L	559_A	0.777	1.00
131_T	135_V	0.777	1.00
513_T	543_G	0.776	1.00
139_G	144_L	0.776	1.00
451_F	503_P	0.770	1.00
173_S	181_F	0.770	1.00
135_V	142_S	0.769	1.00
91_A	95_A	0.766	1.00
93_H	101_E	0.766	1.00
71_K	76_F	0.762	1.00
270_K	273_N	0.761	1.00
235_E	240_E	0.760	1.00
251_E	254_L	0.759	1.00
146_T	152_F	0.759	1.00
133_L	142_S	0.759	1.00
451_F	562_F	0.758	1.00
456_A	545_A	0.758	1.00
91_A	103_Q	0.757	1.00
423_T	426_V	0.757	1.00
548_K	551_D	0.756	1.00
492_S	495_T	0.755	1.00
403_G	436_Y	0.752	1.00
236_I	241_F	0.752	1.00
453_I	507_I	0.752	1.00
169_G	178_I	0.751	1.00
344_K	374_L	0.750	1.00
80_A	109_V	0.749	1.00
196_T	199_Y	0.749	1.00
501_K	532_K	0.748	1.00
385_R	397_M	0.748	1.00
93_H	104_I	0.746	1.00
197_N	201_L	0.744	1.00
236_I	240_E	0.743	1.00
117_D	158_E	0.742	1.00
384_Y	406_D	0.742	1.00
313_V	317_N	0.739	1.00
77_I	97_L	0.737	1.00
304_K	312_E	0.736	1.00
401_D	484_N	0.736	1.00
298_S	301_K	0.735	1.00
185_I	188_L	0.733	1.00
183_G	186_E	0.732	1.00
414_R	448_K	0.731	1.00
108_R	112_S	0.731	1.00
138_N	142_S	0.731	1.00
171_P	177_F	0.729	1.00
206_V	214_T	0.729	1.00
133_L	137_E	0.728	1.00
173_S	176_F	0.728	1.00
322_V	327_Y	0.724	1.00
472_F	476_M	0.721	1.00
158_E	164_S	0.716	1.00
560_L	564_K	0.715	1.00
155_D	200_Y	0.715	1.00
451_F	563_L	0.713	1.00
280_S	283_T	0.711	1.00
163_G	166_V	0.710	1.00
119_K	137_E	0.710	1.00
475_F	480_F	0.709	1.00
352_Y	429_M	0.709	1.00
98_K	102_F	0.708	1.00
70_P	74_L	0.708	1.00
326_E	416_Y	0.706	1.00
154_T	158_E	0.705	1.00
173_S	179_A	0.705	1.00
79_F	101_E	0.703	0.99
148_P	152_F	0.701	0.99
92_I	96_N	0.699	0.99
80_A	112_S	0.697	0.99
241_F	244_I	0.695	0.99
455_G	507_I	0.695	0.99
171_P	176_F	0.695	0.99
170_N	177_F	0.693	0.99
475_F	478_I	0.692	0.99
539_I	542_L	0.690	0.99
172_R	176_F	0.690	0.99
93_H	96_N	0.689	0.99
510_Q	540_P	0.689	0.99
474_G	479_L	0.688	0.99
187_I	191_K	0.688	0.99
462_V	488_M	0.686	0.99
92_I	112_S	0.685	0.99
415_D	418_I	0.685	0.99
69_R	112_S	0.683	0.99
95_A	98_K	0.681	0.99
205_K	227_E	0.680	0.99
176_F	181_F	0.680	0.99
323_G	328_V	0.678	0.99
247_Y	251_E	0.675	0.99
105_E	108_R	0.675	0.99
439_L	457_A	0.675	0.99
88_E	514_R	0.674	0.99
432_S	544_H	0.674	0.99
533_T	565_K	0.674	0.99
445_E	448_K	0.673	0.99
133_L	144_L	0.671	0.99
99_G	104_I	0.671	0.99
289_I	305_V	0.670	0.99
487_L	491_R	0.670	0.99
535_E	540_P	0.670	0.99
224_Y	228_S	0.666	0.99
474_G	481_N	0.665	0.99
328_V	416_Y	0.665	0.99
169_G	181_F	0.664	0.99
342_K	347_G	0.664	0.99
205_K	209_I	0.663	0.99
147_I	153_V	0.663	0.99
225_D	230_K	0.663	0.99
79_F	93_H	0.662	0.99
185_I	190_P	0.662	0.99
101_E	104_I	0.661	0.99
135_V	140_K	0.660	0.99
336_V	394_F	0.658	0.99
433_Y	437_M	0.658	0.99
404_G	491_R	0.655	0.99
438_T	442_V	0.655	0.99
535_E	538_V	0.654	0.99
508_H	520_V	0.652	0.99
517_L	536_F	0.650	0.99
504_L	523_Y	0.650	0.99
272_I	276_K	0.649	0.99
192_E	197_N	0.647	0.99
125_G	132_S	0.646	0.99
503_P	566_L	0.644	0.99
311_I	315_V	0.644	0.99
349_T	417_A	0.642	0.99
240_E	243_A	0.642	0.99
305_V	311_I	0.641	0.99
235_E	242_K	0.640	0.99
475_F	482_G	0.638	0.99
170_N	178_I	0.637	0.99
109_V	125_G	0.635	0.99
105_E	109_V	0.632	0.99
138_N	144_L	0.632	0.99
146_T	150_F	0.631	0.99
454_A	523_Y	0.630	0.99
411_V	444_K	0.629	0.99
244_I	248_Y	0.628	0.99
393_K	396_F	0.627	0.99
206_V	213_E	0.627	0.99
193_G	198_A	0.625	0.99
429_M	453_I	0.623	0.99
171_P	181_F	0.622	0.99
128_Q	143_K	0.621	0.99
83_V	91_A	0.620	0.99
163_G	185_I	0.620	0.99
474_G	480_F	0.619	0.99
507_I	539_I	0.619	0.99
154_T	161_I	0.618	0.99
535_E	539_I	0.616	0.99
76_F	118_D	0.615	0.99
119_K	123_F	0.614	0.99
363_N	366_N	0.613	0.99
348_N	424_N	0.612	0.99
296_L	363_N	0.611	0.99
191_K	194_S	0.611	0.99
116_Y	122_V	0.609	0.99
224_Y	227_E	0.609	0.99
327_Y	337_P	0.607	0.99
326_E	331_K	0.606	0.98
209_I	213_E	0.605	0.98
81_R	101_E	0.605	0.98
177_F	180_D	0.605	0.98
352_Y	381_A	0.604	0.98
255_I	259_K	0.603	0.98
414_R	418_I	0.600	0.98
429_M	563_L	0.596	0.98
352_Y	369_I	0.595	0.98
366_N	369_I	0.595	0.98
116_Y	154_T	0.594	0.98
321_D	328_V	0.594	0.98
505_C	537_H	0.593	0.98
294_S	300_H	0.593	0.98
410_V	428_I	0.593	0.98
407_L	437_M	0.591	0.98
178_I	200_Y	0.591	0.98
346_P	423_T	0.591	0.98
157_N	160_Y	0.591	0.98
431_Y	545_A	0.589	0.98
322_V	325_V	0.589	0.98
323_G	341_I	0.588	0.98
456_A	508_H	0.587	0.98
411_V	441_A	0.586	0.98
107_P	110_R	0.585	0.98
291_F	303_Y	0.581	0.98
242_K	246_I	0.579	0.98
96_N	102_F	0.578	0.98
433_Y	436_Y	0.578	0.98
561_I	564_K	0.577	0.98
196_T	201_L	0.576	0.98
180_D	183_G	0.575	0.98
273_N	276_K	0.575	0.98
321_D	325_V	0.575	0.98
534_Y	538_V	0.574	0.98
323_G	327_Y	0.573	0.98
114_L	118_D	0.570	0.98
361_V	365_W	0.570	0.98
338_T	416_Y	0.570	0.98
194_S	199_Y	0.570	0.98
220_W	239_F	0.568	0.98
330_V	408_R	0.567	0.98
488_M	491_R	0.567	0.98
354_H	384_Y	0.566	0.98
290_Y	314_V	0.566	0.98
277_G	282_A	0.565	0.98
233_R	236_I	0.564	0.98
460_D	492_S	0.562	0.98
82_D	91_A	0.562	0.98
531_G	534_Y	0.561	0.98
339_W	383_N	0.560	0.97
115_T	123_F	0.559	0.97
123_F	126_S	0.559	0.97
475_F	479_L	0.559	0.97
178_I	184_N	0.557	0.97
115_T	122_V	0.557	0.97
277_G	293_H	0.557	0.97
193_G	197_N	0.557	0.97
204_N	211_D	0.555	0.97
122_V	126_S	0.554	0.97
96_N	101_E	0.554	0.97
115_T	154_T	0.554	0.97
383_N	387_S	0.554	0.97
505_C	535_E	0.553	0.97
440_L	443_G	0.553	0.97
360_E	388_T	0.553	0.97
305_V	309_G	0.552	0.97
321_D	327_Y	0.551	0.97
539_I	558_P	0.551	0.97
460_D	495_T	0.551	0.97
330_V	334_V	0.551	0.97
279_I	291_F	0.550	0.97
413_V	417_A	0.550	0.97
562_F	566_L	0.549	0.97
192_E	198_A	0.549	0.97
194_S	201_L	0.548	0.97
346_P	422_I	0.548	0.97
354_H	432_S	0.547	0.97
411_V	414_R	0.546	0.97
471_L	476_M	0.545	0.97
222_Y	229_K	0.545	0.97
201_L	246_I	0.544	0.97
133_L	154_T	0.544	0.97
274_T	277_G	0.541	0.97
218_S	225_D	0.541	0.97
463_E	519_P	0.540	0.97
258_K	263_S	0.538	0.97
337_P	394_F	0.538	0.97
342_K	422_I	0.538	0.97
439_L	504_L	0.536	0.97
177_F	187_I	0.536	0.97
189_T	193_G	0.534	0.97
120_R	124_T	0.534	0.97
116_Y	120_R	0.533	0.97
395_M	399_I	0.533	0.97
193_G	200_Y	0.533	0.97
156_V	162_I	0.533	0.97
68_T	77_I	0.533	0.97
534_Y	539_I	0.532	0.97
190_P	195_V	0.532	0.97
397_M	405_G	0.531	0.97
172_R	181_F	0.530	0.97
476_M	482_G	0.529	0.96
521_M	536_F	0.527	0.96
239_F	259_K	0.525	0.96
364_S	367_L	0.525	0.96
372_L	377_Y	0.525	0.96
197_N	202_M	0.524	0.96
426_V	448_K	0.524	0.96
96_N	99_G	0.523	0.96
218_S	224_Y	0.523	0.96
137_E	140_K	0.523	0.96
355_G	432_S	0.523	0.96
440_L	496_Y	0.521	0.96
322_V	344_K	0.520	0.96
447_D	502_V	0.520	0.96
120_R	126_S	0.520	0.96
184_N	190_P	0.519	0.96
401_D	487_L	0.519	0.96
446_P	502_V	0.518	0.96
173_S	191_K	0.517	0.96
441_A	449_W	0.517	0.96
350_I	377_Y	0.516	0.96
278_T	281_G	0.515	0.96
334_V	394_F	0.514	0.96
270_K	274_T	0.513	0.96
400_G	487_L	0.513	0.96
363_N	368_L	0.513	0.96
510_Q	541_N	0.512	0.96
309_G	316_D	0.511	0.96
406_D	410_V	0.511	0.96
199_Y	202_M	0.511	0.96
99_G	102_F	0.510	0.96
255_I	258_K	0.510	0.96
327_Y	331_K	0.510	0.96
431_Y	555_I	0.509	0.96
504_L	527_L	0.508	0.96
410_V	437_M	0.508	0.96
299_P	365_W	0.506	0.95
122_V	127_S	0.506	0.95
259_K	271_E	0.505	0.95
183_G	188_L	0.504	0.95
542_L	546_I	0.504	0.95
154_T	160_Y	0.502	0.95
198_A	201_L	0.502	0.95
198_A	204_N	0.500	0.95
206_V	223_I	0.500	0.95
205_K	223_I	0.500	0.95

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4bp8A	1	0.9912	100	0.359	Contact Map
2xe4A	1	0.9912	100	0.37	Contact Map
1yr2A	1	0.9666	100	0.378	Contact Map
3iujA	1	0.9684	100	0.38	Contact Map
2bklA	1	0.9824	100	0.386	Contact Map
2xdwA	2	0.9859	100	0.404	Contact Map
4hxfB	4	0.9332	100	0.414	Contact Map
3azoA	1	0.9736	100	0.417	Contact Map
4hvtA	1	0.9824	100	0.418	Contact Map
3o4hA	2	0.9613	100	0.421	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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