GREMLIN Database
RL11 - 50S ribosomal protein L11
UniProt: P96037 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 170 (135)
Sequences: 2402 (967)
Seq/√Len: 83.3

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
34_E38_K3.7431.00
77_L135_L3.6041.00
97_N136_T3.0661.00
77_L98_L2.9961.00
41_E44_S2.9631.00
104_I108_I2.9181.00
100_L127_L2.5391.00
73_T126_M2.5211.00
4_K28_L2.4661.00
99_S102_Q2.4501.00
104_I123_L2.3891.00
89_D93_K2.3841.00
80_E105_K2.2671.00
23_P27_Q2.2221.00
30_L57_V2.1771.00
97_N138_D2.1621.00
51_V68_V2.0661.00
89_D92_H2.0381.00
6_I57_V2.0341.00
81_A98_L1.7301.00
101_E104_I1.7201.00
49_M75_A1.7021.00
38_K42_A1.6991.00
10_V21_L1.6831.00
91_A94_K1.6791.00
94_K136_T1.5701.00
103_V127_L1.5561.00
14_N47_K1.5230.99
103_V123_L1.5030.99
33_G37_K1.4350.99
5_T54_T1.3990.99
16_K36_V1.3830.99
103_V126_M1.3740.99
100_L123_L1.3640.99
116_T121_A1.3020.98
114_L122_A1.3010.98
87_S91_A1.2990.98
54_T69_G1.2980.98
105_K108_I1.2940.98
119_L123_L1.2440.98
70_I112_P1.2420.98
11_E14_N1.2340.98
6_I28_L1.2190.98
20_P23_P1.2070.97
111_K116_T1.2010.97
102_Q105_K1.1850.97
124_K127_L1.1780.97
85_E88_G1.1750.97
101_E105_K1.1680.97
118_S121_A1.1590.97
81_A135_L1.1560.97
111_K122_A1.1370.96
123_L127_L1.1330.96
77_L81_A1.1280.96
117_K121_A1.1240.96
88_G93_K1.1100.96
78_L83_A1.0910.95
49_M79_K1.0820.95
75_A78_L1.0660.95
116_T122_A1.0630.95
100_L103_V1.0600.94
83_A135_L1.0430.94
87_S93_K1.0130.93
107_A119_L1.0110.93
31_N34_E1.0080.93
54_T67_K1.0050.93
46_F51_V0.9990.93
46_F50_S0.9860.92
104_I119_L0.9800.92
105_K109_M0.9780.92
58_D61_T0.9770.92
98_L135_L0.9750.92
27_Q32_V0.9590.91
39_L54_T0.9460.90
74_T129_T0.9400.90
101_E139_N0.9330.90
78_L85_E0.9050.88
34_E37_K0.9050.88
11_E50_S0.9000.88
100_L104_I0.8940.88
77_L130_A0.8940.88
96_G135_L0.8910.87
50_S75_A0.8870.87
30_L63_K0.8870.87
81_A96_G0.8860.87
73_T98_L0.8840.87
76_L109_M0.8810.87
70_I73_T0.8680.86
80_E109_M0.8390.84
115_T125_S0.8320.84
33_G41_E0.8210.83
80_E102_Q0.8200.83
27_Q30_L0.8020.81
15_V22_A0.7980.81
28_L62_K0.7920.81
53_V68_V0.7900.80
14_N84_S0.7810.80
79_K82_G0.7790.79
108_I119_L0.7790.79
35_V39_L0.7670.78
10_V50_S0.7620.78
42_A66_I0.7610.78
6_I30_L0.7560.77
81_A95_I0.7560.77
38_K66_I0.7550.77
33_G64_Y0.7510.77
44_S47_K0.7470.76
21_L66_I0.7460.76
100_L139_N0.7360.75
121_A124_K0.7310.75
58_D65_E0.7290.75
108_I123_L0.7270.75
33_G36_V0.7260.74
80_E106_I0.7260.74
26_S132_S0.7210.74
87_S94_K0.7200.74
88_G91_A0.7160.73
37_K41_E0.7090.73
83_A95_I0.7030.72
120_K124_K0.7020.72
8_I53_V0.6950.71
21_L24_T0.6950.71
28_L57_V0.6790.69
39_L50_S0.6790.69
10_V39_L0.6770.69
74_T91_A0.6750.69
70_I111_K0.6750.69
14_N44_S0.6740.69
14_N48_G0.6730.69
91_A95_I0.6690.68
18_G23_P0.6630.68
128_G132_S0.6550.67
43_T68_V0.6530.66
51_V71_P0.6500.66
24_T57_V0.6490.66
111_K114_L0.6480.66
72_T133_I0.6430.65
42_A68_V0.6420.65
78_L86_P0.6400.65
99_S138_D0.6400.65
114_L125_S0.6300.64
98_L137_V0.6300.64
77_L106_I0.6270.63
6_I55_I0.6250.63
96_G136_T0.6200.62
74_T88_G0.6180.62
8_I21_L0.6180.62
33_G38_K0.6120.61
13_G128_G0.6120.61
23_P57_V0.6110.61
29_G62_K0.6080.61
39_L59_S0.6080.61
16_K32_V0.6050.61
34_E62_K0.6040.60
121_A125_S0.5990.60
38_K41_E0.5960.59
67_K112_P0.5960.59
111_K115_T0.5950.59
85_E93_K0.5950.59
10_V32_V0.5890.59
58_D63_K0.5880.58
33_G44_S0.5860.58
8_I23_P0.5840.58
65_E68_V0.5790.57
28_L129_T0.5720.56
87_S90_P0.5680.56
22_A52_P0.5650.55
120_K123_L0.5610.55
103_V117_K0.5590.55
71_P76_L0.5590.55
115_T122_A0.5570.54
19_P23_P0.5570.54
18_G24_T0.5560.54
38_K64_Y0.5540.54
52_P70_I0.5510.54
34_E59_S0.5490.53
17_P55_I0.5490.53
83_A90_P0.5490.53
81_A137_V0.5480.53
46_F109_M0.5480.53
46_F49_M0.5430.53
26_S29_G0.5420.52
98_L103_V0.5350.51
98_L106_I0.5340.51
62_K68_V0.5340.51
110_K113_G0.5320.51
104_I107_A0.5260.50
82_G102_Q0.5250.50
17_P40_N0.5240.50
59_S62_K0.5210.50
7_K54_T0.5160.49
77_L133_I0.5130.49
35_V40_N0.5120.48
25_L30_L0.5110.48
47_K79_K0.5080.48
47_K50_S0.5070.48
40_N110_K0.5060.48
117_K124_K0.5040.47
100_L120_K0.5020.47
81_A103_V0.5010.47
70_I106_I0.5000.47
52_P72_T0.5000.47
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3j21H 1 0.7824 100 0.063 Contact Map
1vq8I 1 0.4118 100 0.086 Contact Map
3j61K 1 0.7353 100 0.123 Contact Map
4w22K 1 0.8765 100 0.137 Contact Map
3zf7M 1 0.7824 100 0.137 Contact Map
3j7yJ 1 0.7941 100 0.141 Contact Map
3bboK 1 0.8059 100 0.161 Contact Map
3egvB 1 0.4471 100 0.171 Contact Map
4tp9I 1 0.0118 100 0.174 Contact Map
1mmsA 1 0.7824 100 0.179 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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