GPT - SULSO - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

GPT - Putative UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase

UniProt:	P96000	Sequences: MRILAILLPILISFFISYITTVWVIRQAKKSRFVGKDINKPDKPEIPLLGGIGIIAGFIAGSFSLLLTDVRSERVIPAVILSSLLIAFLGLLDDIFNVRQSVRAFLPIFASVPLIVYSVGHSIISIPFLGPINFGIFYYIIIIPFALTITSNAFNMLEGLNGLGVGMGIIMLSALAYIGLTHTGPTYQAGLIALSAIFSLSAFLIFNKYPAKIFPGNVGTYFIGALIGAIGIAGFMYTALAILYIPYVVEFILKLRTNFKGVSFGKVDSSGRLYWDEKPHSLTHIVMKMGRFKEYQVVIILWGMEAIFAVIAVILQTTTIVI	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	322 (295)
Sequences:	6692 (4554)
Seq/√Len:	265.1

ECOLI - WECA MRAY
BACSU - TAGO MRAY
SULSO - GPT

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
256_R	273_L	5.253	1.00
174_A	309_A	4.097	1.00
166_G	302_W	3.980	1.00
275_W	289_M	3.540	1.00
176_A	194_L	3.451	1.00
193_A	230_I	3.330	1.00
99_R	102_V	3.315	1.00
85_L	110_A	2.784	1.00
169_I	197_I	2.705	1.00
37_D	40_K	2.642	1.00
114_L	229_A	2.575	1.00
54_I	215_P	2.529	1.00
92_L	96_F	2.438	1.00
83_S	222_F	2.433	1.00
17_S	202_A	2.431	1.00
173_S	197_I	2.374	1.00
55_I	87_A	2.360	1.00
17_S	57_G	2.289	1.00
293_K	296_Q	2.162	1.00
55_I	84_L	2.137	1.00
165_V	200_L	2.094	1.00
82_S	225_A	2.006	1.00
245_I	308_F	2.000	1.00
59_I	84_L	1.974	1.00
196_A	226_L	1.947	1.00
260_K	268_D	1.932	1.00
25_I	29_K	1.925	1.00
89_L	106_L	1.921	1.00
154_F	168_G	1.905	1.00
57_G	61_G	1.900	1.00
112_V	116_V	1.896	1.00
165_V	204_L	1.889	1.00
168_G	172_L	1.883	1.00
146_A	228_G	1.871	1.00
6_I	194_L	1.856	1.00
192_I	226_L	1.823	1.00
260_K	273_L	1.766	1.00
103_R	107_P	1.742	1.00
58_F	196_A	1.724	1.00
14_F	205_I	1.719	1.00
21_T	53_G	1.718	1.00
16_I	57_G	1.715	1.00
115_I	143_I	1.708	1.00
267_V	273_L	1.707	1.00
112_V	143_I	1.684	1.00
252_I	256_R	1.670	1.00
196_A	223_I	1.646	1.00
82_S	114_L	1.643	1.00
172_L	196_A	1.619	1.00
208_K	299_I	1.589	1.00
18_Y	205_I	1.578	1.00
176_A	193_A	1.575	1.00
126_I	129_L	1.575	1.00
169_I	201_S	1.569	1.00
260_K	269_S	1.568	1.00
91_L	95_I	1.554	1.00
167_M	305_E	1.551	1.00
179_G	234_G	1.542	1.00
137_F	140_I	1.525	1.00
103_R	221_Y	1.510	1.00
54_I	199_S	1.506	1.00
12_I	65_L	1.502	1.00
261_G	270_S	1.501	1.00
27_Q	30_K	1.495	1.00
24_V	53_G	1.494	1.00
292_F	300_I	1.483	1.00
9_P	195_S	1.476	1.00
104_A	107_P	1.475	1.00
180_L	190_G	1.472	1.00
170_I	302_W	1.426	1.00
136_I	140_I	1.418	1.00
22_V	26_R	1.398	1.00
108_I	143_I	1.394	1.00
165_V	169_I	1.375	1.00
108_I	147_L	1.363	1.00
171_M	227_I	1.361	1.00
115_I	142_I	1.342	1.00
55_I	222_F	1.337	1.00
172_L	197_I	1.335	1.00
171_M	305_E	1.319	1.00
168_G	223_I	1.303	1.00
161_N	210_P	1.300	1.00
61_G	195_S	1.296	1.00
145_F	149_I	1.293	1.00
21_T	213_I	1.291	1.00
88_F	92_L	1.271	1.00
142_I	232_I	1.265	1.00
155_N	217_N	1.265	1.00
87_A	218_V	1.263	1.00
26_R	30_K	1.249	1.00
200_L	223_I	1.236	1.00
138_Y	142_I	1.230	1.00
78_A	117_Y	1.229	1.00
209_Y	295_Y	1.222	1.00
27_Q	31_S	1.218	1.00
172_L	227_I	1.215	1.00
108_I	112_V	1.212	1.00
34_V	45_E	1.209	1.00
14_F	202_A	1.208	1.00
282_L	286_V	1.201	1.00
159_G	283_T	1.199	1.00
79_V	189_A	1.195	1.00
59_I	80_I	1.191	1.00
18_Y	202_A	1.184	1.00
54_I	200_L	1.183	1.00
13_S	198_F	1.182	1.00
144_P	148_T	1.173	1.00
172_L	193_A	1.170	1.00
296_Q	300_I	1.163	1.00
254_K	258_N	1.150	1.00
81_L	113_P	1.149	1.00
170_I	309_A	1.145	1.00
299_I	303_G	1.144	1.00
111_S	147_L	1.141	1.00
26_R	29_K	1.138	1.00
179_G	189_A	1.133	1.00
154_F	164_G	1.128	1.00
114_L	146_A	1.128	1.00
202_A	206_F	1.125	1.00
23_W	26_R	1.123	1.00
142_I	146_A	1.119	1.00
86_I	111_S	1.118	1.00
89_L	110_A	1.115	1.00
10_I	198_F	1.114	1.00
305_E	309_A	1.111	1.00
115_I	139_Y	1.110	1.00
152_N	155_N	1.105	1.00
46_I	214_F	1.086	1.00
259_F	269_S	1.076	1.00
25_I	212_K	1.075	1.00
85_L	106_L	1.069	1.00
176_A	197_I	1.069	1.00
111_S	143_I	1.062	1.00
165_V	215_P	1.057	1.00
222_F	226_L	1.049	1.00
170_I	305_E	1.049	1.00
146_A	229_A	1.048	1.00
145_F	231_G	1.039	1.00
121_H	125_S	1.038	1.00
21_T	202_A	1.036	1.00
58_F	83_S	1.035	1.00
107_P	221_Y	1.033	1.00
116_V	120_G	1.033	1.00
252_I	301_L	1.032	1.00
86_I	225_A	1.031	1.00
156_M	257_T	1.031	1.00
42_D	214_F	1.031	1.00
157_L	167_M	1.029	1.00
168_G	200_L	1.027	1.00
22_V	206_F	1.023	1.00
171_M	243_L	1.020	1.00
46_I	211_A	1.014	1.00
195_S	198_F	1.014	1.00
121_H	124_I	1.000	1.00
82_S	110_A	0.999	1.00
90_G	221_Y	0.998	1.00
39_N	42_D	0.998	1.00
86_I	110_A	0.997	1.00
83_S	226_L	0.996	1.00
35_G	40_K	0.991	1.00
160_L	298_V	0.987	1.00
150_T	221_Y	0.981	1.00
292_F	296_Q	0.980	1.00
58_F	199_S	0.977	1.00
104_A	108_I	0.976	1.00
204_L	208_K	0.975	1.00
176_A	179_G	0.963	1.00
57_G	60_A	0.957	1.00
111_S	146_A	0.956	1.00
16_I	61_G	0.954	1.00
137_F	141_I	0.950	1.00
10_I	194_L	0.945	1.00
82_S	229_A	0.943	1.00
198_F	202_A	0.942	1.00
17_S	21_T	0.941	1.00
174_A	313_V	0.936	1.00
20_T	53_G	0.933	1.00
284_H	287_M	0.929	1.00
176_A	180_L	0.928	1.00
172_L	200_L	0.925	1.00
107_P	152_N	0.923	1.00
173_S	177_Y	0.920	1.00
55_I	83_S	0.916	1.00
176_A	190_G	0.915	1.00
275_W	288_K	0.914	1.00
209_Y	294_E	0.912	1.00
103_R	106_L	0.909	1.00
205_I	300_I	0.905	1.00
170_I	306_A	0.897	1.00
13_S	199_S	0.894	1.00
175_L	231_G	0.892	1.00
48_L	218_V	0.890	1.00
179_G	190_G	0.889	1.00
16_I	60_A	0.886	1.00
86_I	106_L	0.886	1.00
168_G	227_I	0.884	1.00
81_L	85_L	0.882	1.00
96_F	99_R	0.880	1.00
23_W	27_Q	0.880	1.00
174_A	243_L	0.877	1.00
19_I	23_W	0.875	1.00
167_M	246_P	0.871	1.00
249_V	282_L	0.866	1.00
62_S	76_I	0.864	1.00
272_R	275_W	0.863	1.00
308_F	312_A	0.861	1.00
79_V	229_A	0.857	1.00
104_A	147_L	0.855	1.00
148_T	257_T	0.853	1.00
107_P	150_T	0.849	1.00
15_F	19_I	0.845	1.00
304_M	308_F	0.842	0.99
271_G	275_W	0.840	0.99
138_Y	141_I	0.837	0.99
124_I	128_F	0.828	0.99
101_S	105_F	0.826	0.99
260_K	271_G	0.824	0.99
135_G	140_I	0.824	0.99
171_M	309_A	0.817	0.99
14_F	18_Y	0.814	0.99
169_I	200_L	0.812	0.99
103_R	150_T	0.807	0.99
16_I	20_T	0.803	0.99
164_G	223_I	0.801	0.99
39_N	276_D	0.800	0.99
8_L	12_I	0.799	0.99
177_Y	313_V	0.797	0.99
175_L	234_G	0.793	0.99
146_A	150_T	0.792	0.99
125_S	128_F	0.791	0.99
9_P	61_G	0.789	0.99
37_D	41_P	0.787	0.99
157_L	283_T	0.782	0.99
214_F	217_N	0.781	0.99
286_V	301_L	0.780	0.99
103_R	156_M	0.780	0.99
111_S	115_I	0.779	0.99
276_D	288_K	0.779	0.99
261_G	272_R	0.774	0.99
79_V	83_S	0.773	0.99
201_S	205_I	0.772	0.99
79_V	226_L	0.770	0.99
249_V	304_M	0.769	0.99
124_I	127_P	0.768	0.99
84_L	88_F	0.768	0.99
141_I	145_F	0.768	0.99
107_P	147_L	0.758	0.99
155_N	214_F	0.756	0.99
303_G	307_I	0.755	0.99
133_N	137_F	0.751	0.99
85_L	89_L	0.751	0.99
177_Y	181_T	0.749	0.99
122_S	133_N	0.748	0.99
256_R	260_K	0.747	0.99
58_F	222_F	0.744	0.99
154_F	171_M	0.744	0.99
209_Y	298_V	0.741	0.99
243_L	312_A	0.739	0.99
14_F	201_S	0.739	0.99
87_A	222_F	0.738	0.99
17_S	54_I	0.735	0.99
9_P	191_L	0.735	0.99
145_F	148_T	0.734	0.99
13_S	61_G	0.732	0.99
165_V	203_F	0.731	0.99
208_K	295_Y	0.730	0.99
92_L	95_I	0.729	0.99
103_R	217_N	0.726	0.98
250_E	283_T	0.721	0.98
170_I	174_A	0.721	0.98
123_I	133_N	0.720	0.98
18_Y	206_F	0.719	0.98
52_I	218_V	0.716	0.98
28_A	213_I	0.714	0.98
259_F	268_D	0.714	0.98
148_T	254_K	0.713	0.98
254_K	257_T	0.709	0.98
102_V	105_F	0.708	0.98
38_I	41_P	0.704	0.98
182_H	186_T	0.704	0.98
140_I	143_I	0.703	0.98
152_N	217_N	0.697	0.98
20_T	57_G	0.696	0.98
192_I	230_I	0.696	0.98
259_F	280_H	0.694	0.98
292_F	297_V	0.693	0.98
190_G	194_L	0.693	0.98
86_I	107_P	0.692	0.98
58_F	62_S	0.691	0.98
286_V	292_F	0.691	0.98
156_M	251_F	0.688	0.98
125_S	129_L	0.688	0.98
270_S	273_L	0.686	0.98
203_F	215_P	0.684	0.98
298_V	302_W	0.681	0.98
124_I	129_L	0.680	0.98
49_L	91_L	0.679	0.98
172_L	226_L	0.677	0.98
256_R	259_F	0.673	0.98
74_R	117_Y	0.672	0.98
300_I	303_G	0.670	0.97
310_V	314_I	0.666	0.97
35_G	48_L	0.664	0.97
28_A	33_F	0.657	0.97
307_I	311_I	0.657	0.97
149_I	228_G	0.656	0.97
10_I	197_I	0.655	0.97
160_L	297_V	0.654	0.97
12_I	61_G	0.653	0.97
36_K	45_E	0.648	0.97
7_L	11_L	0.648	0.97
256_R	280_H	0.647	0.97
41_P	294_E	0.645	0.97
91_L	218_V	0.644	0.97
86_I	150_T	0.642	0.97
225_A	229_A	0.642	0.97
268_D	271_G	0.641	0.97
294_E	298_V	0.639	0.97
25_I	28_A	0.638	0.97
28_A	34_V	0.638	0.97
175_L	193_A	0.636	0.97
13_S	57_G	0.635	0.97
248_V	251_F	0.635	0.97
148_T	153_A	0.634	0.96
256_R	274_Y	0.630	0.96
293_K	297_V	0.630	0.96
232_I	236_M	0.630	0.96
123_I	131_P	0.630	0.96
158_E	215_P	0.630	0.96
114_L	225_A	0.629	0.96
154_F	244_Y	0.628	0.96
253_L	283_T	0.627	0.96
164_G	215_P	0.625	0.96
250_E	254_K	0.621	0.96
238_T	241_A	0.620	0.96
205_I	303_G	0.618	0.96
49_L	95_I	0.617	0.96
10_I	14_F	0.616	0.96
133_N	136_I	0.611	0.96
114_L	118_S	0.609	0.96
142_I	148_T	0.609	0.96
62_S	192_I	0.607	0.95
139_Y	142_I	0.606	0.95
175_L	243_L	0.605	0.95
41_P	287_M	0.604	0.95
11_L	15_F	0.603	0.95
215_P	223_I	0.602	0.95
34_V	48_L	0.601	0.95
89_L	221_Y	0.600	0.95
112_V	139_Y	0.598	0.95
83_S	192_I	0.596	0.95
191_L	195_S	0.595	0.95
29_K	33_F	0.595	0.95
119_V	139_Y	0.594	0.95
169_I	173_S	0.593	0.95
25_I	213_I	0.591	0.95
153_A	251_F	0.588	0.95
255_L	258_N	0.588	0.95
164_G	203_F	0.587	0.95
158_E	219_G	0.586	0.95
38_I	42_D	0.579	0.94
40_K	46_I	0.578	0.94
189_A	233_A	0.577	0.94
111_S	228_G	0.575	0.94
121_H	128_F	0.575	0.94
24_V	28_A	0.573	0.94
28_A	47_P	0.572	0.94
100_Q	104_A	0.572	0.94
36_K	44_P	0.571	0.94
121_H	129_L	0.571	0.94
143_I	148_T	0.571	0.94
50_G	203_F	0.571	0.94
87_A	91_L	0.570	0.94
113_P	117_Y	0.570	0.94
287_M	297_V	0.568	0.94
134_F	138_Y	0.568	0.94
257_T	261_G	0.568	0.94
295_Y	299_I	0.567	0.94
161_N	215_P	0.567	0.94
97_N	274_Y	0.565	0.93
52_I	87_A	0.563	0.93
99_R	103_R	0.563	0.93
161_N	284_H	0.563	0.93
261_G	268_D	0.562	0.93
32_R	36_K	0.560	0.93
158_E	164_G	0.558	0.93
309_A	312_A	0.556	0.93
311_I	315_L	0.556	0.93
123_I	127_P	0.554	0.93
31_S	95_I	0.553	0.93
287_M	290_G	0.551	0.93
72_S	75_V	0.551	0.93
61_G	65_L	0.551	0.93
86_I	221_Y	0.550	0.93
54_I	58_F	0.550	0.93
218_V	221_Y	0.547	0.92
20_T	56_A	0.547	0.92
166_G	298_V	0.547	0.92
37_D	288_K	0.546	0.92
157_L	253_L	0.546	0.92
251_F	255_L	0.546	0.92
100_Q	258_N	0.543	0.92
61_G	64_S	0.543	0.92
69_D	72_S	0.543	0.92
282_L	301_L	0.538	0.92
123_I	126_I	0.537	0.92
58_F	172_L	0.535	0.91
55_I	59_I	0.533	0.91
164_G	253_L	0.531	0.91
144_P	147_L	0.531	0.91
166_G	170_I	0.528	0.91
122_S	125_S	0.526	0.91
297_V	301_L	0.523	0.91
12_I	64_S	0.521	0.90
48_L	294_E	0.520	0.90
107_P	220_T	0.519	0.90
197_I	200_L	0.519	0.90
131_P	134_F	0.518	0.90
139_Y	143_I	0.516	0.90
203_F	214_F	0.515	0.90
140_I	145_F	0.514	0.90
205_I	212_K	0.514	0.90
163_L	298_V	0.513	0.90
280_H	284_H	0.513	0.90
57_G	199_S	0.513	0.90
69_D	74_R	0.513	0.90
231_G	240_L	0.512	0.90
98_V	106_L	0.511	0.90
156_M	261_G	0.511	0.90
40_K	287_M	0.509	0.89
150_T	225_A	0.508	0.89
24_V	27_Q	0.507	0.89
132_I	135_G	0.507	0.89
121_H	127_P	0.505	0.89
171_M	244_Y	0.504	0.89
156_M	221_Y	0.504	0.89
246_P	305_E	0.502	0.89
62_S	68_T	0.501	0.89
153_A	257_T	0.501	0.89
172_L	176_A	0.501	0.89
93_D	155_N	0.500	0.89
120_G	138_Y	0.500	0.89

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4j72A	2	0.8975	100	0.207	Contact Map
4xp4A	1	0.7205	10.6	0.964	Contact Map
2ls4A	1	0.0745	8.3	0.965	Contact Map
1iq5B	1	0.0745	4.3	0.969	Contact Map
2jlnA	1	0.1087	4.1	0.97	Contact Map
4m5bA	1	0.5839	2.8	0.972	Contact Map
4djkA	2	0.1149	2.7	0.973	Contact Map
1ckkB	1	0.0807	2.6	0.973	Contact Map
2b2hA	3	0.1615	2.5	0.973	Contact Map
1ifkA	9	0.0994	2.5	0.973	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0092 seconds.