GREMLIN Database
RS9 - 30S ribosomal protein S9
UniProt: P95992 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 137 (125)
Sequences: 2840 (1297)
Seq/√Len: 116.0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
125_R131_W4.4291.00
56_A60_I4.1501.00
87_A111_L2.8291.00
68_I82_A2.8251.00
21_C85_A2.5711.00
91_V111_L2.4081.00
118_T127_S2.3441.00
125_R132_R2.3181.00
94_T98_E2.2441.00
126_Y132_R2.1361.00
127_S130_R2.1311.00
64_I93_F2.0571.00
9_I22_Y1.9301.00
101_K105_A1.8861.00
51_E110_M1.8641.00
51_E83_R1.8121.00
43_E46_R1.7941.00
7_L22_Y1.7771.00
28_G65_D1.7771.00
16_T117_Q1.7361.00
37_I46_R1.7281.00
41_P46_R1.7131.00
100_E104_R1.6981.00
29_R36_P1.6941.00
13_R88_R1.6351.00
29_R65_D1.6251.00
53_L66_A1.6081.00
91_V100_E1.5831.00
126_Y130_R1.5751.00
26_G65_D1.5001.00
24_Y67_K1.4801.00
60_I99_L1.4751.00
54_L61_R1.4751.00
55_L108_R1.4621.00
57_G61_R1.4361.00
40_I82_A1.3851.00
70_T82_A1.3461.00
56_A99_L1.3321.00
105_A108_R1.3121.00
48_K51_E1.3021.00
35_V38_E1.2570.99
7_L24_Y1.2410.99
80_D83_R1.2380.99
37_I49_I1.2240.99
60_I63_K1.2080.99
76_M80_D1.1910.99
27_K65_D1.1480.99
118_T121_E1.1410.99
60_I64_I1.0920.98
126_Y131_W1.0880.98
10_S89_A1.0680.98
25_A63_K1.0560.98
14_R80_D1.0460.98
50_M61_R1.0390.98
13_R18_R1.0360.98
119_E122_K1.0310.98
127_S132_R1.0250.97
31_F67_K1.0110.97
85_A113_G0.9520.96
94_T99_L0.9500.96
48_K80_D0.9440.96
45_V75_I0.9420.96
83_R110_M0.9410.96
127_S131_W0.9390.96
49_I52_P0.9360.96
93_F99_L0.9330.96
56_A103_Y0.9280.95
13_R84_M0.9250.95
23_I89_A0.9200.95
13_R117_Q0.9160.95
73_G77_G0.9150.95
45_V76_M0.8970.95
24_Y65_D0.8950.95
47_L51_E0.8930.94
11_S85_A0.8910.94
77_G80_D0.8880.94
104_R112_A0.8610.93
17_A77_G0.8530.93
102_I108_R0.8500.93
60_I94_T0.8460.93
55_L110_M0.8450.93
50_M53_L0.8400.92
22_Y69_I0.8300.92
123_W134_K0.8250.92
41_P75_I0.8220.92
34_N69_I0.8170.91
8_V93_F0.8130.91
84_M113_G0.8130.91
23_I66_A0.8110.91
87_A91_V0.8080.91
48_K79_A0.8060.91
44_M47_L0.8060.91
55_L102_I0.8040.91
31_F36_P0.8000.90
112_A115_P0.7990.90
20_T69_I0.7960.90
37_I41_P0.7930.90
42_I75_I0.7900.90
10_S21_C0.7870.90
50_M54_L0.7870.90
91_V99_L0.7810.89
49_I79_A0.7790.89
121_E126_Y0.7750.89
100_E111_L0.7720.89
130_R134_K0.7700.89
23_I64_I0.7580.88
10_S92_K0.7410.87
118_T130_R0.7390.87
9_I69_I0.7320.86
121_E127_S0.7310.86
53_L60_I0.7210.85
30_V37_I0.7200.85
123_W132_R0.7120.85
27_K47_L0.7110.84
53_L62_S0.7090.84
19_A70_T0.7050.84
17_A73_G0.7050.84
47_L50_M0.7020.84
31_F34_N0.6960.83
35_V41_P0.6930.83
8_V91_V0.6920.83
104_R111_L0.6910.83
42_I45_V0.6820.82
9_I20_T0.6770.82
102_I105_A0.6740.81
97_K101_K0.6630.80
46_R49_I0.6610.80
43_E47_L0.6600.80
47_L54_L0.6560.79
48_K110_M0.6510.79
53_L86_L0.6510.79
53_L64_I0.6500.79
94_T97_K0.6490.79
48_K83_R0.6380.78
57_G60_I0.6370.77
97_K102_I0.6370.77
12_A18_R0.6300.77
118_T126_Y0.6300.77
41_P45_V0.6260.76
21_C130_R0.6240.76
32_V36_P0.6230.76
18_R123_W0.6230.76
8_V23_I0.6210.76
24_Y93_F0.6190.75
40_I49_I0.6120.75
56_A61_R0.6100.74
20_T70_T0.6070.74
22_Y118_T0.6050.74
17_A81_A0.6040.74
126_Y134_K0.6010.73
129_R137_R0.5920.72
30_V49_I0.5890.72
31_F69_I0.5860.71
12_A19_A0.5840.71
88_R113_G0.5740.70
40_I120_S0.5710.69
121_E124_M0.5640.69
51_E134_K0.5630.68
19_A32_V0.5590.68
91_V104_R0.5550.67
35_V117_Q0.5540.67
12_A84_M0.5530.67
125_R130_R0.5480.66
126_Y133_Q0.5480.66
10_S23_I0.5460.66
121_E125_R0.5450.66
22_Y77_G0.5400.65
84_M88_R0.5320.64
115_P133_Q0.5310.64
7_L67_K0.5290.64
126_Y135_S0.5290.64
23_I86_L0.5270.63
35_V77_G0.5270.63
41_P82_A0.5250.63
118_T123_W0.5230.63
11_S103_Y0.5210.62
40_I76_M0.5180.62
32_V40_I0.5170.62
63_K71_Y0.5160.62
113_G117_Q0.5100.61
45_V48_K0.5090.61
18_R71_Y0.5080.61
70_T75_I0.5070.60
120_S136_Y0.5060.60
103_Y113_G0.5050.60
121_E128_A0.5020.60
36_P92_K0.5020.60
41_P49_I0.5000.59
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3j20K 1 0.9708 100 0.061 Contact Map
3j7aM 1 0.9562 100 0.07 Contact Map
3j60Q 1 0.8686 100 0.074 Contact Map
4ujpR 1 0.9781 100 0.076 Contact Map
4bpeI 1 0.9854 100 0.079 Contact Map
4w23Q 1 0.9708 100 0.082 Contact Map
4tp8I 1 0.9197 100 0.084 Contact Map
4rb5I 1 0.9197 100 0.085 Contact Map
3bbnI 1 0.9124 100 0.087 Contact Map
5aj3I 1 0.927 100 0.087 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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