GREMLIN Database
RL13 - 50S ribosomal protein L13
UniProt: P95991 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 149 (120)
Sequences: 2998 (1639)
Seq/√Len: 149.6

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
8_Q121_I2.8111.00
52_R73_G2.7181.00
79_S82_N2.4851.00
19_L46_I2.4761.00
57_Y69_P2.4001.00
26_V38_I2.2851.00
46_I72_N2.2841.00
15_E43_K2.0881.00
55_E69_P2.0641.00
35_K106_K1.9981.00
57_Y67_F1.9741.00
82_N85_K1.7501.00
12_I26_V1.7331.00
51_N72_N1.6721.00
16_G45_V1.6601.00
51_N76_R1.6431.00
24_S28_R1.6321.00
84_V88_I1.6241.00
29_L36_V1.6171.00
49_E53_V1.5771.00
30_L105_V1.5751.00
41_G107_I1.5731.00
25_N28_R1.5691.00
29_L123_F1.5661.00
23_A87_T1.5591.00
108_Y115_F1.5511.00
42_E109_V1.4871.00
74_I78_R1.4751.00
108_Y114_E1.4481.00
100_R103_K1.4441.00
89_R102_L1.4361.00
70_Y75_R1.4351.00
42_E110_G1.4261.00
72_N76_R1.3891.00
76_R83_I1.3841.00
14_A22_M1.3731.00
85_K102_L1.3691.00
72_N83_I1.3661.00
11_I39_V1.3641.00
39_V111_V1.3561.00
31_K104_N1.3551.00
63_V66_L1.3511.00
55_E71_R1.3291.00
7_E104_N1.3211.00
71_R74_I1.3211.00
17_Q124_P1.3191.00
70_Y78_R1.3131.00
56_S72_N1.3001.00
70_Y74_I1.2941.00
49_E52_R1.2911.00
86_R90_G1.2621.00
17_Q25_N1.2461.00
92_L98_G1.2371.00
15_E18_I1.2141.00
26_V88_I1.2061.00
14_A38_I1.1951.00
92_L101_M1.1651.00
92_L102_L1.1160.99
51_N83_I1.1150.99
86_R89_R1.1070.99
58_K70_Y1.0920.99
82_N86_R1.0870.99
41_G80_P1.0840.99
19_L44_A1.0780.99
26_V84_V1.0580.99
51_N73_G1.0530.99
88_I105_V1.0480.99
22_M84_V1.0340.99
81_I109_V1.0230.99
10_V123_F1.0140.99
18_I45_V1.0050.99
98_G101_M1.0050.99
80_P109_V0.9950.99
25_N123_F0.9930.99
15_E111_V0.9750.99
22_M26_V0.9650.98
32_E104_N0.9620.98
21_R24_S0.9520.98
101_M104_N0.9320.98
74_I77_P0.9300.98
60_L68_N0.9250.98
35_K104_N0.9010.98
11_I37_I0.9000.97
55_E67_F0.9000.97
106_K114_E0.8960.97
81_I85_K0.8590.97
22_M44_A0.8510.96
14_A44_A0.8510.96
58_K68_N0.8440.96
94_K98_G0.8390.96
19_L87_T0.8360.96
84_V107_I0.8360.96
90_G94_K0.8310.96
102_L107_I0.8080.95
58_K86_R0.8010.95
73_G77_P0.7980.95
85_K107_I0.7900.95
59_L65_T0.7900.95
10_V36_V0.7890.95
25_N29_L0.7870.95
85_K103_K0.7820.94
7_E31_K0.7740.94
12_I22_M0.7720.94
75_R86_R0.7710.94
100_R104_N0.7710.94
94_K101_M0.7700.94
13_N40_N0.7670.94
42_E80_P0.7640.94
75_R79_S0.7600.94
5_V32_E0.7490.93
7_E35_K0.7480.93
96_S99_R0.7410.93
46_I51_N0.7290.92
60_L66_L0.7230.92
44_A84_V0.7110.91
54_I83_I0.7050.91
39_V42_E0.7030.91
59_L63_V0.6990.90
10_V17_Q0.6900.90
26_V36_V0.6760.89
98_G102_L0.6710.88
10_V29_L0.6700.88
37_I115_F0.6670.88
19_L72_N0.6480.87
115_F118_R0.6400.86
62_T66_L0.6280.85
79_S86_R0.6270.85
60_L86_R0.6130.84
17_Q22_M0.6030.83
46_I83_I0.5970.82
19_L84_V0.5970.82
92_L95_S0.5940.82
18_I47_S0.5930.81
10_V121_I0.5870.81
37_I114_E0.5830.80
59_L66_L0.5820.80
41_G109_V0.5780.80
89_R94_K0.5760.80
42_E111_V0.5740.79
43_K110_G0.5640.78
72_N75_R0.5640.78
79_S85_K0.5610.78
117_G120_F0.5610.78
63_V96_S0.5570.77
81_I106_K0.5550.77
41_G81_I0.5550.77
112_P116_E0.5550.77
9_V65_T0.5530.77
41_G84_V0.5530.77
119_Q122_K0.5510.77
29_L32_E0.5480.76
95_S101_M0.5470.76
54_I87_T0.5430.76
23_A84_V0.5370.75
78_R94_K0.5350.74
40_N43_K0.5340.74
26_V29_L0.5330.74
37_I120_F0.5280.74
38_I84_V0.5270.73
12_I24_S0.5260.73
56_S92_L0.5250.73
102_L106_K0.5230.73
59_L67_F0.5230.73
76_R81_I0.5220.73
15_E22_M0.5210.73
94_K102_L0.5210.73
70_Y77_P0.5210.73
36_V123_F0.5200.72
53_V72_N0.5190.72
95_S99_R0.5170.72
9_V50_K0.5160.72
11_I118_R0.5140.72
93_P98_G0.5100.71
58_K67_F0.5070.71
53_V71_R0.5070.71
28_R92_L0.5030.70
30_L102_L0.5020.70
4_Q8_Q0.5020.70
25_N90_G0.5010.70
121_I124_P0.5000.69
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3zf7O 1 0.953 100 0.122 Contact Map
1vq8J 1 0.9262 100 0.13 Contact Map
3j61O 1 0.9933 100 0.148 Contact Map
4cuwO 1 0 100 0.15 Contact Map
1j3aA 1 0.8523 100 0.151 Contact Map
4a17I 1 0.9664 100 0.151 Contact Map
3j39O 1 0.9866 100 0.153 Contact Map
4ujrB 1 0.9597 100 0.155 Contact Map
4w20O 1 0.9597 100 0.157 Contact Map
1vx7K 1 0.9664 100 0.159 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0058 seconds.