GREMLIN Database
RS13 - 30S ribosomal protein S13
UniProt: P95986 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 165 (146)
Sequences: 394 (245)
Seq/√Len: 20.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
126_K136_G4.0101.00
50_A59_E3.9661.00
22_L46_M3.3711.00
110_E117_R3.3571.00
110_E115_S3.2661.00
118_G121_H2.6620.98
23_P38_K2.6530.98
56_S59_E2.5130.98
11_I60_V2.2570.95
83_R91_D2.2200.95
40_I66_V2.1470.94
41_I46_M1.9890.91
114_R122_S1.9880.91
6_K57_D1.9820.91
82_R85_D1.9090.89
106_D121_H1.8940.89
36_T70_H1.8610.88
38_K42_R1.8240.87
5_F96_T1.7870.85
25_A52_L1.7850.85
108_E111_K1.6710.81
138_T141_T1.6350.80
103_V107_I1.6030.78
110_E116_W1.5910.78
69_D115_S1.5400.75
10_R137_R1.4970.73
89_G93_H1.4900.73
76_P81_N1.4890.73
7_Y70_H1.4850.73
64_E68_S1.4670.72
109_R117_R1.4660.72
139_G143_G1.4540.71
50_A56_S1.4520.71
78_W81_N1.4470.71
41_I79_L1.4290.70
16_V28_M1.3810.67
78_W82_R1.3500.65
57_D64_E1.3490.65
9_V52_L1.3480.65
70_H75_L1.3420.65
139_G144_V1.3400.65
23_P37_A1.3380.65
4_Q16_V1.3340.64
106_D118_G1.3170.63
3_Q56_S1.3070.63
94_L131_R1.2920.62
16_V41_I1.2790.61
71_T77_S1.2690.60
24_Y134_T1.2600.60
18_G85_D1.2550.59
81_N85_D1.2500.59
8_V12_F1.2370.58
119_V123_L1.1900.55
86_Y109_R1.1850.55
4_Q24_Y1.1680.54
22_L41_I1.1630.54
8_V133_R1.1590.53
12_F140_M1.1530.53
78_W85_D1.1460.52
44_L66_V1.1040.50
96_T126_K1.0890.49
20_M24_Y1.0850.48
5_F51_R1.0850.48
116_W134_T1.0490.46
102_Y113_S1.0400.46
9_V16_V1.0400.46
7_Y36_T1.0370.45
76_P89_G1.0340.45
16_V60_V1.0340.45
47_D50_A1.0330.45
75_L79_L1.0300.45
108_E122_S1.0230.44
76_P82_R1.0050.43
28_M87_E0.9990.43
94_L99_L0.9940.43
51_R148_K0.9930.43
50_A54_E0.9880.42
81_N89_G0.9810.42
28_M63_V0.9730.41
60_V84_K0.9710.41
33_G104_R0.9630.41
18_G53_G0.9570.40
106_D110_E0.9500.40
4_Q142_I0.9490.40
30_K100_I0.9390.39
57_D65_S0.9260.38
21_K50_A0.9230.38
133_R138_T0.9230.38
32_I36_T0.9070.37
18_G143_G0.9000.37
15_D88_S0.8920.36
78_W89_G0.8900.36
14_Q46_M0.8890.36
19_T96_T0.8790.35
33_G53_G0.8700.35
74_G84_K0.8690.35
61_K138_T0.8680.35
48_P100_I0.8550.34
5_F16_V0.8450.33
45_G91_D0.8430.33
139_G147_K0.8380.33
120_R137_R0.8360.33
55_L99_L0.8290.33
141_T145_A0.8150.32
60_V105_N0.8110.31
63_V66_V0.8060.31
34_Y75_L0.8060.31
56_S125_L0.8050.31
8_V92_L0.8040.31
40_I45_G0.8020.31
63_V145_A0.7980.31
18_G81_N0.7940.31
82_R106_D0.7910.30
108_E124_G0.7910.30
116_W126_K0.7860.30
143_G146_R0.7850.30
76_P85_D0.7800.30
23_P142_I0.7770.30
48_P63_V0.7760.30
4_Q73_K0.7750.30
29_V146_R0.7690.29
53_G76_P0.7660.29
40_I110_E0.7530.28
126_K135_T0.7490.28
45_G75_L0.7480.28
67_I95_V0.7420.28
4_Q11_I0.7390.28
139_G146_R0.7300.27
97_S123_L0.7290.27
97_S104_R0.7270.27
40_I69_D0.7260.27
96_T136_G0.7210.27
141_T146_R0.7200.27
70_H74_G0.7200.27
42_R142_I0.7120.26
116_W121_H0.7110.26
30_K138_T0.7050.26
5_F19_T0.7040.26
135_T142_I0.7020.26
17_D99_L0.6980.26
107_I128_R0.6940.25
30_K40_I0.6940.25
55_L97_S0.6920.25
16_V109_R0.6800.25
56_S62_K0.6790.25
25_A114_R0.6750.24
49_N77_S0.6710.24
62_K112_K0.6680.24
144_V147_K0.6670.24
3_Q12_F0.6610.24
103_V140_M0.6590.24
7_Y104_R0.6520.23
65_S71_T0.6520.23
77_S91_D0.6480.23
53_G82_R0.6400.23
10_R120_R0.6340.22
23_P26_L0.6290.22
108_E114_R0.6280.22
32_I71_T0.6240.22
116_W131_R0.6200.22
11_I16_V0.6200.22
108_E126_K0.6160.22
50_A110_E0.6140.22
4_Q45_G0.6130.22
35_N134_T0.6070.21
16_V22_L0.6030.21
18_G89_G0.6010.21
47_D82_R0.6000.21
61_K68_S0.5990.21
36_T74_G0.5970.21
20_M57_D0.5960.21
39_A94_L0.5950.21
5_F105_N0.5950.21
25_A125_L0.5920.21
78_W144_V0.5910.21
71_T91_D0.5900.21
60_V86_Y0.5850.20
136_G139_G0.5840.20
65_S73_K0.5840.20
22_L74_G0.5840.20
4_Q22_L0.5820.20
80_Y146_R0.5810.20
39_A88_S0.5810.20
130_Q137_R0.5800.20
65_S68_S0.5800.20
54_E92_L0.5780.20
9_V122_S0.5760.20
129_G132_T0.5680.20
84_K142_I0.5630.19
21_K49_N0.5610.19
129_G137_R0.5600.19
20_M131_R0.5590.19
64_E116_W0.5570.19
139_G148_K0.5510.19
36_T72_I0.5500.19
37_A115_S0.5480.19
99_L138_T0.5480.19
26_L67_I0.5460.19
10_R35_N0.5430.19
81_N144_V0.5370.18
63_V95_V0.5350.18
78_W106_D0.5310.18
26_L120_R0.5290.18
102_Y106_D0.5280.18
49_N124_G0.5280.18
43_K54_E0.5280.18
86_Y99_L0.5260.18
25_A105_N0.5260.18
101_F107_I0.5220.18
49_N95_V0.5190.18
13_G35_N0.5130.17
11_I40_I0.5130.17
17_D80_Y0.5120.17
6_K25_A0.5110.17
89_G144_V0.5100.17
34_Y44_L0.5100.17
27_A34_Y0.5060.17
32_I102_Y0.5050.17
59_E66_V0.5000.17
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3j60S 1 0.897 100 0.143 Contact Map
4bpeM 1 0.897 100 0.146 Contact Map
3j7aS 1 0.7758 100 0.147 Contact Map
3j38S 1 0.8303 100 0.147 Contact Map
3j20O 1 0.897 100 0.147 Contact Map
3zeyM 1 0.897 100 0.147 Contact Map
4ujpT 1 0.8485 100 0.198 Contact Map
4rb5M 1 0.7212 100 0.397 Contact Map
4tp8M 1 0.6909 100 0.442 Contact Map
3bbnM 1 0.6 100 0.468 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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