DPOL3 - SULSO - GREMLIN Contacts

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DPOL3 - DNA polymerase 3

UniProt:	P95979	Sequences: MIKDFFILDFSYEIKGNTPLVYIWSVDDEGNSSVVIDNNFRPYFYIIYEGNENEIIENIKKNCEALQITKVKRKYLGNIVDALLIQTSTPTQIKKCREKISELNNIKGIFDADIRYTMRYSLDFDLRPFTWFRAEVNEVKFDGFRTKKAYILDKILSHYEGNMPELRTIGVDFQIYSKYGSLNPRKDPIVVMSLWSKEGPMQFSLDEGIDDLKIIRRFVDYILNYDPDIIFVYDSDLLPWKYITERASSLGVKIDIGRKIGSEVSVGTYGHYSISGRLNVDLTGLLVNERSLGHVDLIDVSNYLGISPSRYSFKWYEISRYWDNEKNRRIIREYSIENARSIYLLGNYLLSTYSELVKIVGLPLDKLSVASWGNRIETSLIRTATKSGELIPIRMDNPNRPSKIKKNIIIQPKVGIYTDVYVLDISSVYSLVIRKFNIAPDTLVKEQCDDCYSSPISNYKFKREPSGLYKTFLDELSNVRDSNKIKVIEELISSFNDYVHWVNARWYSREIASAFDEFSNEIIRFIIDLIKSSGLDVILANDLLIFVTGGSRDKVNELITKINSLYNLDVKVKIFYKSLLVLDNNRYAGLSEGDKIDIARKGEEDMNLCELARNIKRKIIEEILISKDVKKAIKLVKSTVIKLRRGEFDNEELITWAKIERDLNEYNNQLPFVTAARKAIQSGYLISKDSKIGYVIVKGLGPLNDRAEPFFLVKEKNRIDIEYYVDQIFRETLKLLKPLGVNEESLKKTNITDILDLFGASKKK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	764 (687)
Sequences:	1999 (1153)
Seq/√Len:	44.0

ECOLI - DPO2
HALSA - Q9HRV9 Q9HHJ8
SULSO - DPOL3 DPOL1 DPOL2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
559_I	563_N	8.501	1.00
559_I	566_Y	7.203	1.00
563_N	566_Y	7.156	1.00
413_K	536_D	5.537	1.00
614_N	652_E	5.467	1.00
308_P	344_L	5.388	1.00
642_K	647_E	5.133	1.00
192_M	218_F	4.707	1.00
559_I	562_I	4.166	1.00
189_I	243_I	4.157	1.00
638_S	642_K	3.953	1.00
557_E	561_K	3.914	1.00
317_E	320_R	3.760	1.00
466_S	474_D	3.685	1.00
320_R	324_N	3.661	1.00
87_T	96_C	3.589	1.00
562_I	566_Y	3.547	1.00
556_N	559_I	3.336	1.00
43_Y	123_D	3.295	1.00
643_L	653_L	3.264	1.00
222_I	230_I	3.210	1.00
73_R	388_G	3.210	1.00
171_V	218_F	3.171	1.00
210_D	213_K	3.138	1.00
709_P	712_L	3.078	1.00
206_D	217_R	3.039	1.00
453_S	456_I	2.917	1.00
558_L	566_Y	2.909	1.00
615_I	639_T	2.909	1.00
208_G	217_R	2.870	1.00
618_K	622_E	2.779	1.00
527_I	531_K	2.718	1.00
72_K	81_D	2.698	1.00
211_D	246_R	2.664	1.00
79_I	84_L	2.620	1.00
308_P	337_E	2.616	1.00
239_P	338_N	2.523	1.00
217_R	220_D	2.489	1.00
706_R	720_D	2.466	1.00
361_G	382_R	2.465	1.00
212_L	216_R	2.461	1.00
558_L	563_N	2.426	1.00
695_V	719_I	2.425	1.00
457_S	460_K	2.423	1.00
387_S	471_T	2.411	1.00
318_I	322_W	2.409	1.00
708_E	712_L	2.408	1.00
317_E	321_Y	2.388	1.00
226_D	258_R	2.380	1.00
72_K	79_I	2.379	1.00
166_L	229_I	2.364	1.00
683_G	686_I	2.342	1.00
634_K	638_S	2.340	1.00
234_D	239_P	2.298	1.00
556_N	563_N	2.286	1.00
722_E	726_D	2.259	1.00
556_N	566_Y	2.242	1.00
377_E	505_R	2.218	1.00
337_E	340_R	2.214	1.00
561_K	565_L	2.213	1.00
383_T	475_E	2.211	1.00
302_N	309_S	2.203	1.00
576_Y	597_D	2.158	1.00
558_L	562_I	2.129	1.00
474_D	478_N	2.129	1.00
232_V	235_S	2.087	0.99
696_I	723_Y	2.047	0.99
702_P	705_D	2.035	0.99
696_I	707_A	2.032	0.99
558_L	565_L	2.022	0.99
383_T	386_K	2.020	0.99
258_R	277_R	1.991	0.99
617_R	621_E	1.971	0.99
644_R	722_E	1.969	0.99
226_D	277_R	1.968	0.99
742_N	745_S	1.949	0.99
560_T	564_S	1.942	0.99
46_I	85_I	1.929	0.99
229_I	350_L	1.921	0.99
678_K	712_L	1.914	0.99
318_I	321_Y	1.880	0.99
467_G	470_K	1.849	0.99
674_T	678_K	1.834	0.99
193_S	339_A	1.825	0.99
588_A	601_K	1.817	0.98
174_Q	338_N	1.810	0.98
422_V	546_F	1.806	0.98
90_P	93_I	1.794	0.98
172_D	334_Y	1.792	0.98
69_T	84_L	1.786	0.98
452_Y	456_I	1.779	0.98
556_N	560_T	1.767	0.98
79_I	82_A	1.765	0.98
621_E	625_I	1.757	0.98
642_K	648_F	1.753	0.98
320_R	323_D	1.752	0.98
379_S	491_L	1.745	0.98
294_H	299_D	1.736	0.98
656_W	691_K	1.729	0.98
437_N	442_T	1.720	0.98
318_I	324_N	1.711	0.98
79_I	85_I	1.708	0.98
556_N	562_I	1.694	0.98
317_E	322_W	1.681	0.97
525_F	528_D	1.679	0.97
67_Q	86_Q	1.678	0.97
496_N	512_A	1.676	0.97
301_S	341_S	1.675	0.97
559_I	565_L	1.657	0.97
125_D	386_K	1.648	0.97
239_P	310_R	1.647	0.97
169_I	194_L	1.640	0.97
173_F	192_M	1.631	0.97
168_T	229_I	1.626	0.97
635_L	639_T	1.624	0.97
170_G	342_I	1.624	0.97
310_R	338_N	1.614	0.97
174_Q	239_P	1.611	0.97
234_D	238_L	1.604	0.97
338_N	516_D	1.591	0.96
641_I	645_R	1.587	0.96
458_N	461_F	1.586	0.96
602_G	734_K	1.586	0.96
219_V	223_L	1.577	0.96
698_K	718_R	1.577	0.96
536_D	548_T	1.573	0.96
321_Y	325_E	1.567	0.96
618_K	621_E	1.565	0.96
436_F	522_I	1.562	0.96
174_Q	310_R	1.551	0.96
74_K	79_I	1.550	0.96
426_S	571_K	1.541	0.96
457_S	461_F	1.540	0.96
245_E	248_S	1.535	0.96
172_D	338_N	1.535	0.96
90_P	116_Y	1.528	0.95
710_F	713_V	1.514	0.95
469_Y	499_V	1.513	0.95
604_E	672_F	1.512	0.95
682_S	686_I	1.511	0.95
437_N	467_G	1.510	0.95
208_G	214_I	1.505	0.95
452_Y	455_P	1.499	0.95
314_K	318_I	1.489	0.95
477_S	492_I	1.488	0.95
41_R	67_Q	1.482	0.95
234_D	283_T	1.471	0.94
406_K	409_I	1.471	0.94
554_K	557_E	1.468	0.94
628_D	631_K	1.467	0.94
629_V	632_A	1.463	0.94
340_R	344_L	1.460	0.94
540_A	544_L	1.443	0.94
311_Y	333_E	1.440	0.94
710_F	714_K	1.431	0.94
265_S	269_Y	1.429	0.94
583_D	735_L	1.427	0.93
42_P	111_D	1.422	0.93
90_P	94_K	1.413	0.93
512_A	519_S	1.411	0.93
293_G	613_R	1.411	0.93
169_I	222_I	1.403	0.93
454_S	460_K	1.395	0.93
116_Y	123_D	1.392	0.93
615_I	635_L	1.391	0.93
126_L	250_L	1.388	0.93
574_I	597_D	1.385	0.92
561_K	564_S	1.375	0.92
476_L	488_I	1.372	0.92
609_C	727_Q	1.366	0.92
574_I	589_G	1.365	0.92
174_Q	238_L	1.364	0.92
384_A	441_D	1.362	0.92
238_L	338_N	1.354	0.92
384_A	468_L	1.353	0.92
234_D	338_N	1.353	0.92
312_S	338_N	1.345	0.91
172_D	239_P	1.345	0.91
659_I	673_V	1.343	0.91
78_N	85_I	1.336	0.91
189_I	194_L	1.333	0.91
169_I	218_F	1.331	0.91
191_V	194_L	1.326	0.91
321_Y	324_N	1.321	0.91
50_G	72_K	1.321	0.91
422_V	589_G	1.304	0.90
356_L	487_V	1.303	0.90
409_I	584_N	1.297	0.90
265_S	270_G	1.291	0.89
119_R	123_D	1.291	0.89
442_T	467_G	1.289	0.89
174_Q	334_Y	1.287	0.89
622_E	631_K	1.285	0.89
406_K	516_D	1.283	0.89
541_N	585_N	1.283	0.89
292_L	300_V	1.281	0.89
459_Y	462_K	1.277	0.89
228_D	277_R	1.277	0.89
460_K	463_R	1.263	0.88
317_E	324_N	1.258	0.88
662_D	665_E	1.254	0.88
191_V	332_R	1.254	0.88
282_L	342_I	1.252	0.88
174_Q	234_D	1.249	0.88
580_L	588_A	1.242	0.88
588_A	624_L	1.237	0.87
657_A	694_Y	1.237	0.87
130_T	153_D	1.235	0.87
173_F	234_D	1.234	0.87
522_I	526_I	1.234	0.87
577_K	594_D	1.233	0.87
533_S	561_K	1.233	0.87
152_L	155_I	1.230	0.87
43_Y	119_R	1.224	0.87
310_R	341_S	1.222	0.87
455_P	460_K	1.222	0.87
353_Y	364_L	1.221	0.87
320_R	325_E	1.204	0.86
172_D	310_R	1.200	0.86
73_R	390_L	1.196	0.86
212_L	250_L	1.189	0.85
234_D	310_R	1.186	0.85
46_I	109_I	1.179	0.85
618_K	635_L	1.179	0.85
381_I	391_I	1.177	0.85
298_I	309_S	1.176	0.85
310_R	334_Y	1.176	0.85
136_V	139_V	1.174	0.84
314_K	317_E	1.174	0.84
670_L	673_V	1.173	0.84
425_I	431_L	1.170	0.84
79_I	83_L	1.165	0.84
732_T	736_L	1.165	0.84
480_R	485_I	1.165	0.84
558_L	561_K	1.163	0.84
265_S	268_T	1.162	0.84
47_I	110_F	1.158	0.84
404_I	409_I	1.156	0.83
317_E	325_E	1.151	0.83
109_I	112_A	1.149	0.83
427_S	490_E	1.148	0.83
296_D	301_S	1.146	0.83
132_F	136_V	1.144	0.83
530_I	558_L	1.137	0.82
662_D	688_K	1.136	0.82
498_Y	504_A	1.134	0.82
522_I	568_L	1.124	0.82
223_L	256_I	1.123	0.82
297_L	338_N	1.118	0.81
530_I	545_I	1.115	0.81
634_K	637_K	1.115	0.81
129_F	354_S	1.113	0.81
306_I	341_S	1.104	0.81
287_V	295_V	1.103	0.80
701_G	705_D	1.099	0.80
586_R	602_G	1.098	0.80
242_Y	246_R	1.096	0.80
278_L	364_L	1.093	0.80
75_Y	78_N	1.092	0.80
483_N	488_I	1.091	0.80
123_D	388_G	1.090	0.80
355_E	358_K	1.088	0.80
678_K	708_E	1.086	0.79
729_F	744_E	1.085	0.79
383_T	472_F	1.084	0.79
523_I	545_I	1.081	0.79
363_P	366_K	1.081	0.79
334_Y	338_N	1.080	0.79
607_N	657_A	1.080	0.79
524_R	528_D	1.076	0.79
663_L	677_R	1.075	0.79
436_F	568_L	1.074	0.79
173_F	189_I	1.074	0.79
68_I	83_L	1.072	0.79
526_I	545_I	1.069	0.78
78_N	84_L	1.069	0.78
338_N	406_K	1.067	0.78
285_L	349_L	1.066	0.78
459_Y	463_R	1.066	0.78
216_R	220_D	1.065	0.78
111_D	114_I	1.057	0.78
467_G	471_T	1.056	0.77
560_T	566_Y	1.056	0.77
133_R	138_E	1.052	0.77
130_T	134_A	1.049	0.77
235_S	279_N	1.049	0.77
66_L	72_K	1.048	0.77
87_T	93_I	1.045	0.77
373_G	507_Y	1.043	0.77
460_K	514_A	1.043	0.77
392_P	415_G	1.036	0.76
643_L	728_I	1.034	0.76
551_S	554_K	1.032	0.76
70_K	74_K	1.027	0.75
228_D	258_R	1.026	0.75
422_V	574_I	1.026	0.75
93_I	97_R	1.026	0.75
89_T	94_K	1.025	0.75
238_L	283_T	1.025	0.75
651_E	714_K	1.024	0.75
561_K	566_Y	1.020	0.75
612_A	731_E	1.019	0.75
195_W	343_Y	1.017	0.75
193_S	335_S	1.014	0.75
615_I	619_I	1.011	0.74
377_E	498_Y	1.010	0.74
297_L	310_R	1.010	0.74
167_R	225_Y	1.010	0.74
403_K	502_V	1.009	0.74
197_K	343_Y	1.004	0.74
643_L	725_V	1.003	0.74
633_I	741_V	1.003	0.74
319_S	323_D	1.002	0.74
322_W	325_E	0.998	0.73
90_P	96_C	0.995	0.73
44_F	93_I	0.995	0.73
531_K	536_D	0.994	0.73
89_T	93_I	0.990	0.73
496_N	519_S	0.990	0.73
421_Y	547_V	0.989	0.73
226_D	361_G	0.986	0.72
546_F	589_G	0.985	0.72
338_N	341_S	0.983	0.72
244_T	248_S	0.980	0.72
37_D	120_Y	0.979	0.72
494_S	516_D	0.977	0.72
239_P	334_Y	0.974	0.72
193_S	196_S	0.972	0.71
602_G	605_D	0.972	0.71
432_V	522_I	0.971	0.71
709_P	713_V	0.971	0.71
675_A	707_A	0.970	0.71
562_I	565_L	0.970	0.71
134_A	142_D	0.970	0.71
534_G	552_R	0.968	0.71
676_A	720_D	0.962	0.71
94_K	134_A	0.958	0.70
387_S	468_L	0.954	0.70
608_L	612_A	0.948	0.69
278_L	381_I	0.946	0.69
87_T	94_K	0.944	0.69
172_D	234_D	0.943	0.69
70_K	73_R	0.939	0.69
581_V	599_A	0.937	0.69
173_F	341_S	0.937	0.69
172_D	297_L	0.935	0.68
54_E	67_Q	0.933	0.68
677_R	680_I	0.931	0.68
500_H	512_A	0.928	0.68
217_R	224_N	0.928	0.68
655_T	727_Q	0.926	0.68
727_Q	730_R	0.926	0.68
170_G	339_A	0.924	0.67
556_N	561_K	0.923	0.67
411_Q	434_R	0.921	0.67
525_F	529_L	0.920	0.67
289_E	486_K	0.919	0.67
701_G	708_E	0.919	0.67
455_P	463_R	0.919	0.67
315_W	319_S	0.918	0.67
35_V	39_N	0.918	0.67
489_E	497_D	0.915	0.67
505_R	602_G	0.915	0.67
420_V	690_S	0.914	0.67
67_Q	70_K	0.911	0.66
312_S	315_W	0.910	0.66
293_G	299_D	0.908	0.66
297_L	334_Y	0.907	0.66
406_K	415_G	0.907	0.66
90_P	112_A	0.902	0.66
284_G	287_V	0.900	0.65
222_I	256_I	0.898	0.65
500_H	544_L	0.896	0.65
723_Y	734_K	0.895	0.65
298_I	302_N	0.894	0.65
639_T	642_K	0.892	0.65
282_L	346_G	0.891	0.65
172_D	238_L	0.890	0.65
414_V	583_D	0.889	0.64
497_D	542_D	0.889	0.64
313_F	317_E	0.888	0.64
476_L	676_A	0.887	0.64
612_A	727_Q	0.886	0.64
51_N	66_L	0.885	0.64
703_L	723_Y	0.885	0.64
659_I	663_L	0.885	0.64
579_L	589_G	0.882	0.64
55_I	66_L	0.881	0.64
420_V	538_I	0.877	0.63
281_D	406_K	0.875	0.63
530_I	562_I	0.873	0.63
230_I	308_P	0.873	0.63
189_I	246_R	0.869	0.63
598_I	601_K	0.867	0.62
426_S	569_D	0.867	0.62
636_V	725_V	0.865	0.62
215_I	464_E	0.865	0.62
414_V	517_E	0.864	0.62
604_E	607_N	0.864	0.62
602_G	616_K	0.864	0.62
542_D	600_R	0.861	0.62
360_V	579_L	0.860	0.62
130_T	243_I	0.859	0.62
184_P	189_I	0.853	0.61
331_I	423_L	0.853	0.61
310_R	335_S	0.851	0.61
39_N	67_Q	0.850	0.61
190_V	193_S	0.850	0.61
76_L	79_I	0.850	0.61
88_S	142_D	0.850	0.61
722_E	747_K	0.849	0.61
435_K	567_N	0.848	0.61
194_L	221_Y	0.847	0.61
528_D	532_S	0.846	0.61
54_E	66_L	0.845	0.60
426_S	470_K	0.845	0.60
453_S	463_R	0.845	0.60
431_L	539_L	0.844	0.60
449_D	698_K	0.843	0.60
94_K	97_R	0.843	0.60
425_I	476_L	0.842	0.60
318_I	325_E	0.841	0.60
427_S	544_L	0.840	0.60
48_Y	83_L	0.840	0.60
115_R	118_M	0.840	0.60
170_G	231_F	0.839	0.60
43_Y	84_L	0.838	0.60
619_I	692_I	0.837	0.60
211_D	214_I	0.837	0.60
35_V	134_A	0.837	0.60
238_L	310_R	0.837	0.60
243_I	254_I	0.837	0.60
89_T	92_Q	0.836	0.60
479_V	482_S	0.836	0.60
55_I	83_L	0.835	0.60
287_V	658_K	0.835	0.60
70_K	79_I	0.834	0.59
686_I	691_K	0.833	0.59
135_E	154_K	0.832	0.59
610_E	613_R	0.831	0.59
557_E	565_L	0.831	0.59
630_K	634_K	0.830	0.59
608_L	730_R	0.830	0.59
497_D	543_L	0.828	0.59
228_D	276_G	0.828	0.59
67_Q	80_V	0.823	0.58
243_I	258_R	0.821	0.58
219_V	255_D	0.820	0.58
432_V	568_L	0.820	0.58
209_I	213_K	0.813	0.57
452_Y	457_S	0.813	0.57
77_G	80_V	0.810	0.57
316_Y	321_Y	0.810	0.57
359_I	488_I	0.809	0.57
79_I	86_Q	0.809	0.57
733_L	737_K	0.805	0.57
175_I	190_V	0.804	0.57
136_V	141_F	0.804	0.57
133_R	390_L	0.803	0.57
277_R	537_V	0.803	0.57
82_A	86_Q	0.803	0.57
402_S	405_K	0.802	0.56
401_P	405_K	0.801	0.56
219_V	247_A	0.800	0.56
543_L	600_R	0.800	0.56
234_D	301_S	0.800	0.56
210_D	216_R	0.799	0.56
500_H	672_F	0.799	0.56
171_V	240_W	0.798	0.56
404_I	500_H	0.796	0.56
89_T	95_K	0.795	0.56
335_S	339_A	0.793	0.56
371_S	586_R	0.792	0.55
92_Q	95_K	0.791	0.55
238_L	334_Y	0.791	0.55
395_M	728_I	0.791	0.55
104_N	107_K	0.791	0.55
601_K	616_K	0.790	0.55
449_D	454_S	0.789	0.55
95_K	99_K	0.789	0.55
640_V	644_R	0.787	0.55
233_Y	345_L	0.787	0.55
41_R	46_I	0.786	0.55
239_P	516_D	0.785	0.55
457_S	462_K	0.784	0.55
356_L	360_V	0.783	0.55
699_G	706_R	0.782	0.55
97_R	100_I	0.781	0.54
215_I	243_I	0.781	0.54
439_A	442_T	0.781	0.54
50_G	66_L	0.781	0.54
173_F	243_I	0.780	0.54
507_Y	691_K	0.780	0.54
315_W	318_I	0.780	0.54
72_K	94_K	0.780	0.54
725_V	729_F	0.778	0.54
91_T	98_E	0.778	0.54
96_C	99_K	0.777	0.54
430_S	600_R	0.776	0.54
297_L	487_V	0.775	0.54
450_D	464_E	0.775	0.54
321_Y	330_I	0.774	0.54
55_I	79_I	0.774	0.54
498_Y	506_W	0.771	0.53
175_I	242_Y	0.769	0.53
196_S	225_Y	0.769	0.53
84_L	87_T	0.768	0.53
404_I	509_R	0.767	0.53
285_L	350_L	0.767	0.53
497_D	600_R	0.767	0.53
84_L	88_S	0.762	0.53
215_I	247_A	0.762	0.53
67_Q	88_S	0.762	0.53
274_I	349_L	0.761	0.53
91_T	94_K	0.761	0.53
551_S	555_V	0.760	0.52
310_R	406_K	0.759	0.52
71_V	88_S	0.758	0.52
492_I	606_M	0.757	0.52
489_E	542_D	0.756	0.52
94_K	98_E	0.755	0.52
453_S	459_Y	0.755	0.52
661_R	665_E	0.755	0.52
598_I	604_E	0.754	0.52
614_N	618_K	0.754	0.52
75_Y	79_I	0.753	0.52
420_V	579_L	0.753	0.52
174_Q	341_S	0.751	0.52
331_I	359_I	0.750	0.51
141_F	562_I	0.750	0.51
96_C	103_L	0.749	0.51
317_E	323_D	0.748	0.51
297_L	406_K	0.748	0.51
174_Q	297_L	0.746	0.51
682_S	685_L	0.745	0.51
88_S	97_R	0.744	0.51
428_V	519_S	0.744	0.51
194_L	218_F	0.744	0.51
66_L	144_F	0.743	0.51
155_I	159_Y	0.742	0.51
230_I	274_I	0.741	0.51
236_D	279_N	0.740	0.51
720_D	731_E	0.740	0.51
560_T	563_N	0.740	0.51
185_R	245_E	0.739	0.50
530_I	581_V	0.738	0.50
55_I	71_V	0.738	0.50
383_T	387_S	0.736	0.50
440_P	616_K	0.734	0.50
111_D	119_R	0.733	0.50
425_I	539_L	0.732	0.50
304_L	345_L	0.732	0.50
172_D	516_D	0.729	0.49
219_V	252_V	0.727	0.49
86_Q	123_D	0.726	0.49
610_E	614_N	0.725	0.49
336_I	570_V	0.725	0.49
371_S	501_W	0.725	0.49
126_L	614_N	0.725	0.49
455_P	461_F	0.724	0.49
222_I	528_D	0.723	0.49
174_Q	335_S	0.722	0.49
380_L	487_V	0.721	0.49
168_T	231_F	0.721	0.49
501_W	589_G	0.721	0.49
528_D	531_K	0.720	0.49
489_E	543_L	0.717	0.48
216_R	252_V	0.716	0.48
49_E	52_E	0.715	0.48
608_L	727_Q	0.715	0.48
492_I	498_Y	0.714	0.48
44_F	621_E	0.714	0.48
693_G	709_P	0.712	0.48
197_K	531_K	0.712	0.48
68_I	71_V	0.711	0.48
424_D	429_Y	0.711	0.48
539_L	544_L	0.709	0.48
220_D	634_K	0.709	0.48
557_E	564_S	0.708	0.47
203_F	336_I	0.707	0.47
655_T	734_K	0.707	0.47
501_W	574_I	0.707	0.47
128_P	361_G	0.706	0.47
42_P	49_E	0.706	0.47
74_K	390_L	0.706	0.47
187_D	193_S	0.704	0.47
240_W	689_D	0.702	0.47
412_P	520_N	0.702	0.47
52_E	55_I	0.701	0.47
356_L	375_R	0.699	0.47
281_D	494_S	0.698	0.46
603_E	731_E	0.697	0.46
51_N	54_E	0.696	0.46
410_I	558_L	0.696	0.46
439_A	609_C	0.695	0.46
233_Y	663_L	0.695	0.46
622_E	625_I	0.695	0.46
724_Y	727_Q	0.695	0.46
626_S	746_L	0.694	0.46
55_I	253_K	0.694	0.46
334_Y	341_S	0.692	0.46
239_P	283_T	0.691	0.46
431_L	483_N	0.690	0.46
423_L	558_L	0.689	0.46
234_D	516_D	0.689	0.46
497_D	544_L	0.688	0.46
645_R	651_E	0.688	0.46
663_L	670_L	0.687	0.45
540_A	546_F	0.686	0.45
226_D	276_G	0.686	0.45
605_D	666_Y	0.684	0.45
605_D	609_C	0.682	0.45
47_I	82_A	0.681	0.45
335_S	736_L	0.681	0.45
586_R	653_L	0.679	0.45
458_N	463_R	0.679	0.45
544_L	547_V	0.678	0.45
276_G	427_S	0.677	0.44
589_G	602_G	0.677	0.44
542_D	585_N	0.675	0.44
233_Y	300_V	0.674	0.44
505_R	734_K	0.672	0.44
655_T	723_Y	0.671	0.44
473_L	515_F	0.671	0.44
588_A	623_I	0.671	0.44
126_L	132_F	0.669	0.44
693_G	710_F	0.669	0.44
539_L	546_F	0.667	0.44
313_F	321_Y	0.666	0.43
501_W	578_S	0.666	0.43
678_K	707_A	0.665	0.43
322_W	328_R	0.664	0.43
112_A	393_I	0.664	0.43
384_A	499_V	0.663	0.43
282_L	515_F	0.663	0.43
87_T	90_P	0.663	0.43
438_I	568_L	0.662	0.43
570_V	591_S	0.661	0.43
440_P	582_L	0.660	0.43
53_N	85_I	0.659	0.43
135_E	153_D	0.657	0.43
222_I	654_I	0.656	0.42
86_Q	100_I	0.656	0.42
66_L	69_T	0.656	0.42
379_S	407_N	0.655	0.42
406_K	585_N	0.655	0.42
633_I	745_S	0.655	0.42
629_V	741_V	0.654	0.42
84_L	94_K	0.653	0.42
311_Y	330_I	0.652	0.42
499_V	612_A	0.651	0.42
407_N	426_S	0.650	0.42
674_T	677_R	0.650	0.42
40_F	43_Y	0.649	0.42
603_E	616_K	0.649	0.42
561_K	651_E	0.649	0.42
589_G	597_D	0.648	0.42
47_I	80_V	0.647	0.42
239_P	406_K	0.647	0.42
68_I	189_I	0.646	0.42
352_T	379_S	0.645	0.41
166_L	380_L	0.645	0.41
494_S	571_K	0.645	0.41
694_Y	724_Y	0.645	0.41
35_V	96_C	0.644	0.41
449_D	634_K	0.644	0.41
613_R	617_R	0.644	0.41
371_S	530_I	0.644	0.41
114_I	119_R	0.641	0.41
53_N	301_S	0.641	0.41
228_D	607_N	0.641	0.41
247_A	653_L	0.641	0.41
47_I	67_Q	0.641	0.41
231_F	650_N	0.640	0.41
310_R	516_D	0.639	0.41
454_S	457_S	0.639	0.41
91_T	95_K	0.639	0.41
443_L	508_S	0.637	0.41
493_S	497_D	0.635	0.41
134_A	144_F	0.635	0.41
636_V	746_L	0.634	0.40
598_I	620_I	0.634	0.40
371_S	657_A	0.634	0.40
285_L	289_E	0.634	0.40
133_R	205_L	0.633	0.40
245_E	249_S	0.633	0.40
402_S	406_K	0.633	0.40
134_A	140_K	0.630	0.40
87_T	95_K	0.630	0.40
543_L	585_N	0.630	0.40
104_N	108_G	0.629	0.40
493_S	519_S	0.629	0.40
695_V	726_D	0.628	0.40
456_I	459_Y	0.628	0.40
496_N	599_A	0.628	0.40
234_D	341_S	0.628	0.40
670_L	674_T	0.626	0.40
657_A	672_F	0.626	0.40
432_V	707_A	0.625	0.40
469_Y	694_Y	0.625	0.40
609_C	612_A	0.625	0.40
729_F	747_K	0.625	0.40
223_L	255_D	0.624	0.40
485_I	520_N	0.624	0.40
295_V	691_K	0.623	0.39
661_R	696_I	0.623	0.39
220_D	223_L	0.623	0.39
424_D	587_Y	0.622	0.39
426_S	490_E	0.622	0.39
277_R	361_G	0.622	0.39
54_E	528_D	0.622	0.39
610_E	652_E	0.621	0.39
47_I	66_L	0.619	0.39
42_P	48_Y	0.619	0.39
356_L	654_I	0.619	0.39
78_N	82_A	0.618	0.39
466_S	471_T	0.618	0.39
50_G	99_K	0.617	0.39
423_L	566_Y	0.617	0.39
192_M	713_V	0.616	0.39
741_V	744_E	0.616	0.39
650_N	698_K	0.616	0.39
385_T	391_I	0.616	0.39
189_I	193_S	0.616	0.39
461_F	599_A	0.614	0.39
278_L	388_G	0.613	0.38
297_L	516_D	0.613	0.38
705_D	711_F	0.612	0.38
301_S	553_D	0.612	0.38
489_E	600_R	0.612	0.38
73_R	385_T	0.610	0.38
639_T	648_F	0.609	0.38
345_L	697_V	0.609	0.38
423_L	559_I	0.608	0.38
561_K	638_S	0.608	0.38
425_I	508_S	0.607	0.38
375_R	492_I	0.607	0.38
185_R	192_M	0.607	0.38
580_L	738_P	0.607	0.38
440_P	499_V	0.606	0.38
181_S	190_V	0.605	0.38
259_K	262_S	0.605	0.38
35_V	51_N	0.604	0.38
178_K	188_P	0.603	0.38
136_V	144_F	0.603	0.38
240_W	268_T	0.602	0.38
366_K	374_N	0.602	0.38
596_I	621_E	0.601	0.37
82_A	426_S	0.599	0.37
138_E	142_D	0.599	0.37
606_M	691_K	0.599	0.37
88_S	92_Q	0.599	0.37
298_I	301_S	0.598	0.37
97_R	112_A	0.598	0.37
67_Q	79_I	0.597	0.37
350_L	601_K	0.597	0.37
406_K	519_S	0.597	0.37
568_L	692_I	0.597	0.37
94_K	99_K	0.596	0.37
192_M	195_W	0.595	0.37
458_N	462_K	0.595	0.37
330_I	333_E	0.594	0.37
138_E	144_F	0.593	0.37
733_L	743_E	0.593	0.37
310_R	573_K	0.593	0.37
170_G	359_I	0.593	0.37
181_S	192_M	0.592	0.37
401_P	406_K	0.592	0.37
438_I	490_E	0.592	0.37
377_E	394_R	0.592	0.37
673_V	676_A	0.592	0.37
487_V	519_S	0.591	0.37
189_I	192_M	0.591	0.37
485_I	497_D	0.590	0.36
41_R	55_I	0.589	0.36
195_W	339_A	0.589	0.36
375_R	609_C	0.589	0.36
475_E	482_S	0.588	0.36
211_D	468_L	0.586	0.36
497_D	585_N	0.586	0.36
296_D	562_I	0.586	0.36
99_K	103_L	0.586	0.36
359_I	402_S	0.585	0.36
449_D	638_S	0.585	0.36
73_R	140_K	0.585	0.36
209_I	212_L	0.584	0.36
636_V	640_V	0.584	0.36
51_N	95_K	0.584	0.36
442_T	520_N	0.583	0.36
277_R	607_N	0.583	0.36
220_D	251_G	0.582	0.36
80_V	138_E	0.580	0.36
213_K	217_R	0.579	0.35
232_V	276_G	0.579	0.35
470_K	492_I	0.579	0.35
454_S	664_N	0.579	0.35
419_D	507_Y	0.578	0.35
611_L	696_I	0.578	0.35
452_Y	460_K	0.578	0.35
52_E	66_L	0.578	0.35
407_N	516_D	0.578	0.35
172_D	300_V	0.578	0.35
353_Y	367_L	0.577	0.35
498_Y	512_A	0.577	0.35
425_I	473_L	0.577	0.35
365_D	369_V	0.576	0.35
456_I	513_S	0.575	0.35
97_R	101_S	0.575	0.35
638_S	647_E	0.575	0.35
499_V	567_N	0.574	0.35
375_R	440_P	0.574	0.35
618_K	642_K	0.573	0.35
456_I	460_K	0.573	0.35
409_I	516_D	0.573	0.35
728_I	732_T	0.572	0.35
450_D	698_K	0.572	0.35
225_Y	348_Y	0.572	0.35
77_G	86_Q	0.571	0.35
177_S	319_S	0.571	0.35
234_D	334_Y	0.571	0.35
231_F	346_G	0.570	0.35
336_I	340_R	0.570	0.35
501_W	507_Y	0.569	0.35
137_N	142_D	0.569	0.35
214_I	411_Q	0.569	0.35
699_G	705_D	0.569	0.35
450_D	466_S	0.569	0.35
136_V	140_K	0.569	0.35
679_A	701_G	0.568	0.34
633_I	742_N	0.568	0.34
282_L	439_A	0.568	0.34
379_S	472_F	0.568	0.34
427_S	504_A	0.567	0.34
119_R	122_L	0.566	0.34
78_N	81_D	0.566	0.34
103_L	107_K	0.566	0.34
50_G	55_I	0.566	0.34
430_S	542_D	0.566	0.34
66_L	76_L	0.565	0.34
455_P	517_E	0.564	0.34
374_N	407_N	0.563	0.34
46_I	89_T	0.562	0.34
67_Q	143_G	0.561	0.34
173_F	334_Y	0.561	0.34
138_E	141_F	0.560	0.34
674_T	707_A	0.560	0.34
432_V	514_A	0.560	0.34
236_D	369_V	0.559	0.34
456_I	462_K	0.559	0.34
41_R	86_Q	0.559	0.34
435_K	499_V	0.559	0.34
585_N	600_R	0.559	0.34
406_K	494_S	0.558	0.34
416_I	743_E	0.557	0.34
281_D	516_D	0.557	0.34
410_I	540_A	0.557	0.34
118_M	122_L	0.556	0.33
337_E	344_L	0.556	0.33
440_P	506_W	0.556	0.33
553_D	681_Q	0.556	0.33
301_S	479_V	0.556	0.33
96_C	101_S	0.556	0.33
53_N	74_K	0.556	0.33
171_V	230_I	0.555	0.33
409_I	415_G	0.555	0.33
488_I	492_I	0.555	0.33
356_L	372_W	0.555	0.33
114_I	381_I	0.554	0.33
131_W	192_M	0.554	0.33
355_E	576_Y	0.554	0.33
234_D	406_K	0.553	0.33
335_S	338_N	0.552	0.33
79_I	88_S	0.552	0.33
40_F	116_Y	0.552	0.33
188_P	242_Y	0.552	0.33
125_D	144_F	0.551	0.33
49_E	55_I	0.550	0.33
93_I	119_R	0.549	0.33
594_D	625_I	0.549	0.33
224_N	681_Q	0.549	0.33
627_K	644_R	0.549	0.33
740_G	743_E	0.549	0.33
48_Y	51_N	0.548	0.33
521_E	525_F	0.548	0.33
277_R	588_A	0.548	0.33
69_T	86_Q	0.548	0.33
233_Y	282_L	0.547	0.33
492_I	607_N	0.547	0.33
410_I	604_E	0.547	0.33
595_K	638_S	0.547	0.33
698_K	720_D	0.547	0.33
695_V	747_K	0.546	0.33
255_D	263_E	0.545	0.33
458_N	514_A	0.544	0.32
82_A	390_L	0.544	0.32
223_L	391_I	0.544	0.32
427_S	430_S	0.544	0.32
439_A	520_N	0.544	0.32
416_I	738_P	0.543	0.32
609_C	723_Y	0.543	0.32
109_I	393_I	0.543	0.32
484_K	601_K	0.543	0.32
47_I	74_K	0.542	0.32
100_I	554_K	0.542	0.32
426_S	505_R	0.541	0.32
220_D	224_N	0.541	0.32
55_I	70_K	0.541	0.32
124_F	132_F	0.540	0.32
238_L	406_K	0.540	0.32
637_K	746_L	0.539	0.32
611_L	728_I	0.539	0.32
204_S	224_N	0.538	0.32
306_I	473_L	0.538	0.32
168_T	350_L	0.538	0.32
511_I	574_I	0.538	0.32
118_M	374_N	0.537	0.32
527_I	643_L	0.537	0.32
720_D	724_Y	0.537	0.32
669_Q	674_T	0.537	0.32
270_G	552_R	0.537	0.32
55_I	74_K	0.536	0.32
128_P	132_F	0.536	0.32
274_I	650_N	0.536	0.32
576_Y	612_A	0.535	0.32
470_K	607_N	0.535	0.32
37_D	45_Y	0.535	0.32
512_A	599_A	0.534	0.32
295_V	428_V	0.534	0.32
294_H	494_S	0.533	0.32
348_Y	433_I	0.533	0.32
199_G	222_I	0.533	0.32
630_K	633_I	0.533	0.32
431_L	724_Y	0.532	0.31
585_N	605_D	0.532	0.31
412_P	523_I	0.531	0.31
238_L	516_D	0.531	0.31
69_T	73_R	0.531	0.31
173_F	239_P	0.531	0.31
223_L	735_L	0.531	0.31
403_K	420_V	0.531	0.31
230_I	253_K	0.531	0.31
141_F	144_F	0.530	0.31
285_L	353_Y	0.530	0.31
189_I	219_V	0.530	0.31
172_D	406_K	0.529	0.31
673_V	690_S	0.529	0.31
292_L	606_M	0.529	0.31
70_K	565_L	0.529	0.31
361_G	727_Q	0.528	0.31
404_I	512_A	0.527	0.31
659_I	672_F	0.527	0.31
477_S	734_K	0.526	0.31
415_G	487_V	0.526	0.31
740_G	745_S	0.526	0.31
189_I	638_S	0.526	0.31
231_F	282_L	0.525	0.31
68_I	78_N	0.523	0.31
173_F	215_I	0.523	0.31
281_D	338_N	0.523	0.31
328_R	589_G	0.522	0.31
190_V	331_I	0.522	0.31
430_S	543_L	0.522	0.31
187_D	371_S	0.521	0.31
541_N	584_N	0.521	0.31
129_F	285_L	0.520	0.30
599_A	724_Y	0.520	0.30
229_I	278_L	0.520	0.30
355_E	691_K	0.519	0.30
231_F	433_I	0.519	0.30
373_G	501_W	0.519	0.30
253_K	262_S	0.519	0.30
81_D	556_N	0.519	0.30
44_F	47_I	0.518	0.30
231_F	343_Y	0.518	0.30
111_D	123_D	0.518	0.30
546_F	579_L	0.518	0.30
529_L	533_S	0.518	0.30
605_D	727_Q	0.517	0.30
232_V	239_P	0.517	0.30
247_A	699_G	0.517	0.30
47_I	68_I	0.517	0.30
189_I	196_S	0.517	0.30
588_A	676_A	0.516	0.30
412_P	581_V	0.515	0.30
448_C	451_C	0.515	0.30
98_E	117_T	0.515	0.30
297_L	409_I	0.514	0.30
299_D	521_E	0.514	0.30
420_V	679_A	0.514	0.30
723_Y	727_Q	0.514	0.30
54_E	136_V	0.513	0.30
70_K	81_D	0.513	0.30
424_D	542_D	0.513	0.30
186_K	209_I	0.512	0.30
604_E	696_I	0.512	0.30
377_E	501_W	0.512	0.30
729_F	743_E	0.511	0.30
427_S	477_S	0.511	0.30
135_E	212_L	0.510	0.30
633_I	637_K	0.510	0.30
133_R	139_V	0.510	0.30
174_Q	301_S	0.510	0.30
455_P	514_A	0.509	0.30
384_A	440_P	0.509	0.30
663_L	666_Y	0.509	0.30
301_S	344_L	0.508	0.29
601_K	606_M	0.508	0.29
115_R	658_K	0.508	0.29
373_G	440_P	0.508	0.29
372_W	494_S	0.507	0.29
682_S	687_S	0.507	0.29
422_V	579_L	0.506	0.29
436_F	523_I	0.506	0.29
638_S	641_I	0.506	0.29
573_K	640_V	0.506	0.29
374_N	498_Y	0.505	0.29
227_P	602_G	0.504	0.29
216_R	265_S	0.504	0.29
659_I	675_A	0.503	0.29
429_Y	587_Y	0.503	0.29
582_L	670_L	0.503	0.29
55_I	138_E	0.502	0.29
42_P	89_T	0.502	0.29
372_W	602_G	0.502	0.29
259_K	275_S	0.501	0.29
183_N	186_K	0.501	0.29
167_R	722_E	0.501	0.29
426_S	492_I	0.501	0.29
54_E	88_S	0.500	0.29
545_I	550_G	0.500	0.29

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1qhtA	1	0.8704	100	0.197	Contact Map
3iayA	1	0.9647	100	0.2	Contact Map
4qclA	1	0.9581	100	0.234	Contact Map
2gv9A	1	0.9634	100	0.236	Contact Map
4fvmA	1	0.9202	100	0.239	Contact Map
4m8oA	1	0.9385	100	0.252	Contact Map
1s5jA	1	0.8181	100	0.252	Contact Map
3k59A	1	0.9202	100	0.268	Contact Map
3qexA	1	0.8927	100	0.328	Contact Map
2py5A	2	0.5812	100	0.66	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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