SYFA - SULSO - GREMLIN Contacts

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SYFA - Phenylalanine--tRNA ligase alpha subunit

UniProt:	P95961	Sequences: MISMLSENEAKILFFLKDLKKTNSVELAIKMGIPESSVLSLIELLREKGYVKTEVKSEKHYVLTEEGRKRKESGLPEDILINTLNGQEKDLNEIKNILNKDFNIAISWAKRKGLIDIKEGKVIPKVKTYMSSEYLALSNLERADSNTINLLKKRGLIEEKERKIVSVELIKEPKESEIGISNLNRELIISGEWKKYKLKKYNVEAFPPYYTISKKHYFREFLEKVKDIMISLGFKEINTGYIEMEFYNFDLLFQPQDHPAREIHDSFSVEGSGKIEDKDLLNNVKEIHEKFWKYEWKQDITLRLMLRSQTTATTARVLASRPKAPQKVFTLGKVFRPDAIDATHLIEFHQLDGVIIDNNFTFKELLGVLKEIFYRLGIKEVKFKPAYFPFTEPSVEAYGYLEKLGWVEMCGAGLLRPEILSSVGIDSTAGAWGIGIERLAMSFLNISDIRLLYSNNIEYIRDTKVKIE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	468 (452)
Sequences:	596 (392)
Seq/√Len:	18.4

BACSU - SYFA
HALSA - SYFA
SULSO - SYFA

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
78_D	126_V	4.858	1.00
187_L	192_E	4.292	1.00
69_K	73_S	3.996	1.00
400_Y	405_G	3.758	1.00
65_E	68_R	3.646	1.00
254_Q	264_H	3.340	1.00
52_K	168_E	3.338	1.00
177_E	197_K	3.244	0.99
59_K	159_E	3.175	0.99
380_E	402_E	3.069	0.99
68_R	138_S	3.020	0.99
134_Y	140_L	2.931	0.99
80_L	94_I	2.920	0.99
282_N	285_K	2.902	0.99
296_W	301_T	2.777	0.98
70_R	76_P	2.764	0.98
170_I	173_P	2.531	0.97
378_I	399_G	2.500	0.97
83_T	98_L	2.418	0.96
380_E	406_W	2.403	0.96
414_L	420_L	2.376	0.95
386_A	398_Y	2.348	0.95
280_L	423_V	2.347	0.95
264_H	305_M	2.345	0.95
68_R	72_E	2.340	0.95
333_K	453_Y	2.274	0.94
421_S	427_S	2.240	0.94
362_F	412_A	2.230	0.93
410_C	434_I	2.214	0.93
232_L	387_Y	2.160	0.92
395_V	412_A	2.150	0.92
218_F	437_E	2.136	0.92
286_E	290_K	2.130	0.92
266_S	338_D	2.122	0.92
388_F	411_G	2.111	0.91
373_F	390_F	2.100	0.91
441_M	449_I	2.078	0.91
169_L	173_P	2.075	0.91
399_G	402_E	2.066	0.90
128_T	131_S	2.064	0.90
128_T	134_Y	2.061	0.90
268_S	338_D	2.011	0.89
402_E	405_G	1.994	0.89
229_M	402_E	1.986	0.89
245_E	268_S	1.984	0.88
57_S	161_E	1.982	0.88
94_I	359_N	1.971	0.88
360_F	430_G	1.962	0.88
355_I	422_S	1.930	0.87
218_F	330_T	1.899	0.86
67_G	71_K	1.887	0.86
249_F	254_Q	1.858	0.85
202_N	343_T	1.853	0.85
330_T	352_D	1.847	0.84
108_W	111_R	1.841	0.84
185_R	189_I	1.836	0.84
180_I	196_Y	1.829	0.84
278_K	282_N	1.817	0.83
300_I	303_R	1.805	0.83
289_E	295_E	1.801	0.83
390_F	437_E	1.775	0.82
69_K	79_I	1.766	0.82
84_L	101_D	1.766	0.82
382_K	406_W	1.763	0.82
246_F	284_V	1.757	0.81
218_F	444_L	1.754	0.81
263_I	268_S	1.742	0.81
109_A	114_L	1.718	0.80
224_K	443_F	1.706	0.79
66_E	156_L	1.702	0.79
150_L	153_K	1.684	0.78
397_A	410_C	1.681	0.78
191_G	194_K	1.667	0.78
384_K	398_Y	1.657	0.77
231_S	375_R	1.656	0.77
440_A	452_L	1.651	0.77
67_G	145_S	1.649	0.77
391_T	394_S	1.629	0.76
39_L	43_E	1.599	0.75
359_N	386_A	1.597	0.75
84_L	115_I	1.593	0.74
215_K	220_E	1.585	0.74
42_I	53_T	1.573	0.73
384_K	388_F	1.562	0.73
167_V	407_V	1.550	0.72
245_E	303_R	1.541	0.72
245_E	305_M	1.534	0.71
109_A	115_I	1.533	0.71
278_K	298_Q	1.519	0.71
281_L	296_W	1.501	0.70
369_L	397_A	1.501	0.70
390_F	410_C	1.491	0.69
245_E	304_L	1.490	0.69
54_E	166_S	1.490	0.69
218_F	345_L	1.480	0.69
429_A	432_W	1.468	0.68
238_N	317_V	1.467	0.68
437_E	444_L	1.466	0.68
217_Y	352_D	1.462	0.68
116_D	122_V	1.452	0.67
225_V	435_G	1.449	0.67
90_D	120_G	1.448	0.67
76_P	115_I	1.430	0.66
440_A	446_I	1.428	0.66
193_W	198_L	1.425	0.66
352_D	390_F	1.425	0.66
380_E	400_Y	1.421	0.65
369_L	376_L	1.419	0.65
61_Y	159_E	1.417	0.65
80_L	105_A	1.411	0.65
66_E	70_R	1.406	0.65
404_L	407_V	1.405	0.64
192_E	195_K	1.402	0.64
357_D	361_T	1.392	0.64
420_L	449_I	1.390	0.64
379_K	402_E	1.388	0.63
315_A	419_I	1.385	0.63
221_F	440_A	1.383	0.63
237_I	314_T	1.364	0.62
388_F	396_E	1.357	0.62
174_K	188_I	1.353	0.61
266_S	308_S	1.350	0.61
361_T	364_E	1.341	0.61
308_S	338_D	1.340	0.61
131_S	135_L	1.332	0.60
113_G	122_V	1.324	0.60
110_K	117_I	1.323	0.60
364_E	367_G	1.319	0.59
237_I	388_F	1.309	0.59
406_W	452_L	1.308	0.59
79_I	269_V	1.307	0.59
272_S	314_T	1.307	0.59
245_E	390_F	1.302	0.58
9_E	76_P	1.300	0.58
106_I	110_K	1.297	0.58
309_Q	390_F	1.292	0.58
305_M	369_L	1.289	0.58
340_I	346_I	1.289	0.58
384_K	396_E	1.288	0.58
325_P	357_D	1.286	0.57
249_F	332_G	1.279	0.57
132_S	135_L	1.278	0.57
355_I	430_G	1.277	0.57
330_T	437_E	1.275	0.57
369_L	386_A	1.267	0.56
224_K	351_L	1.266	0.56
390_F	434_I	1.264	0.56
308_S	429_A	1.264	0.56
274_K	302_L	1.255	0.56
191_G	445_N	1.250	0.55
366_L	397_A	1.246	0.55
218_F	337_P	1.241	0.55
245_E	266_S	1.240	0.55
254_Q	263_I	1.238	0.54
346_I	384_K	1.234	0.54
151_L	154_R	1.233	0.54
66_E	154_R	1.223	0.54
349_H	437_E	1.221	0.53
229_M	314_T	1.221	0.53
98_L	102_F	1.220	0.53
259_P	432_W	1.213	0.53
281_L	298_Q	1.208	0.53
62_V	160_K	1.207	0.53
411_G	454_S	1.201	0.52
259_P	393_P	1.196	0.52
345_L	437_E	1.190	0.52
367_G	406_W	1.187	0.51
337_P	454_S	1.180	0.51
117_I	120_G	1.177	0.51
264_H	268_S	1.174	0.51
297_K	302_L	1.171	0.50
135_L	138_S	1.167	0.50
264_H	309_Q	1.166	0.50
448_D	451_L	1.163	0.50
266_S	300_I	1.161	0.50
254_Q	313_T	1.161	0.50
447_S	453_Y	1.156	0.49
422_S	434_I	1.155	0.49
254_Q	301_T	1.151	0.49
43_E	268_S	1.151	0.49
217_Y	372_I	1.148	0.49
49_G	172_E	1.147	0.49
399_G	407_V	1.147	0.49
20_K	60_H	1.142	0.49
381_V	444_L	1.138	0.48
352_D	372_I	1.128	0.48
188_I	193_W	1.124	0.47
333_K	382_K	1.117	0.47
19_L	49_G	1.117	0.47
247_Y	338_D	1.115	0.47
48_K	91_L	1.111	0.47
13_L	45_L	1.103	0.46
323_K	327_K	1.103	0.46
218_F	395_V	1.099	0.46
218_F	351_L	1.094	0.46
34_P	37_S	1.090	0.45
103_N	232_L	1.090	0.45
85_N	89_K	1.086	0.45
448_D	456_N	1.085	0.45
83_T	87_Q	1.081	0.45
301_T	431_A	1.081	0.45
264_H	338_D	1.076	0.44
364_E	430_G	1.075	0.44
214_K	264_H	1.073	0.44
253_F	422_S	1.069	0.44
388_F	454_S	1.068	0.44
29_I	186_E	1.064	0.44
255_P	372_I	1.057	0.43
83_T	277_D	1.053	0.43
309_Q	337_P	1.044	0.42
229_M	390_F	1.043	0.42
437_E	454_S	1.042	0.42
136_A	143_A	1.040	0.42
417_P	449_I	1.030	0.42
452_L	457_I	1.028	0.42
131_S	134_Y	1.028	0.42
32_G	123_I	1.026	0.41
103_N	107_S	1.023	0.41
165_V	382_K	1.013	0.41
131_S	137_L	1.013	0.41
157_I	161_E	1.007	0.40
388_F	435_G	1.007	0.40
80_L	107_S	1.006	0.40
245_E	300_I	1.006	0.40
411_G	420_L	1.005	0.40
103_N	409_M	1.005	0.40
237_I	330_T	1.003	0.40
84_L	262_E	1.003	0.40
12_I	71_K	1.002	0.40
67_G	303_R	1.001	0.40
24_S	42_I	1.001	0.40
264_H	308_S	0.996	0.40
190_S	196_Y	0.995	0.40
390_F	454_S	0.992	0.39
379_K	382_K	0.987	0.39
112_K	269_V	0.974	0.38
373_F	437_E	0.973	0.38
49_G	361_T	0.970	0.38
181_S	305_M	0.969	0.38
249_F	266_S	0.967	0.38
152_K	285_K	0.966	0.38
218_F	436_I	0.966	0.38
76_P	103_N	0.964	0.38
10_A	14_F	0.964	0.38
388_F	412_A	0.960	0.37
235_K	328_V	0.957	0.37
316_R	320_S	0.957	0.37
16_L	224_K	0.957	0.37
61_Y	148_I	0.956	0.37
45_L	176_S	0.954	0.37
259_P	392_E	0.950	0.37
144_D	147_T	0.950	0.37
14_F	18_D	0.948	0.37
426_D	440_A	0.948	0.37
109_A	407_V	0.946	0.37
82_N	125_K	0.945	0.37
104_I	156_L	0.945	0.37
106_I	117_I	0.941	0.36
76_P	108_W	0.940	0.36
166_S	171_K	0.938	0.36
263_I	308_S	0.938	0.36
254_Q	395_V	0.937	0.36
47_E	161_E	0.936	0.36
414_L	430_G	0.935	0.36
38_V	378_I	0.928	0.36
108_W	112_K	0.927	0.36
337_P	366_L	0.927	0.36
143_A	147_T	0.925	0.35
317_V	432_W	0.924	0.35
43_E	46_R	0.923	0.35
217_Y	255_P	0.922	0.35
12_I	41_L	0.922	0.35
245_E	338_D	0.922	0.35
116_D	297_K	0.920	0.35
244_M	275_I	0.920	0.35
113_G	367_G	0.919	0.35
193_W	260_A	0.915	0.35
249_F	400_Y	0.909	0.35
183_L	239_T	0.909	0.35
214_K	431_A	0.906	0.34
65_E	192_E	0.905	0.34
337_P	345_L	0.905	0.34
218_F	352_D	0.904	0.34
127_K	132_S	0.904	0.34
146_N	153_K	0.900	0.34
351_L	437_E	0.900	0.34
229_M	264_H	0.898	0.34
93_E	97_I	0.893	0.34
384_K	412_A	0.892	0.34
162_R	366_L	0.891	0.34
87_Q	301_T	0.890	0.33
76_P	80_L	0.885	0.33
395_V	437_E	0.885	0.33
337_P	388_F	0.883	0.33
249_F	337_P	0.883	0.33
28_A	163_K	0.882	0.33
330_T	390_F	0.882	0.33
277_D	445_N	0.882	0.33
86_G	125_K	0.881	0.33
409_M	431_A	0.876	0.33
412_A	437_E	0.876	0.33
194_K	283_N	0.873	0.33
67_G	159_E	0.869	0.32
362_F	366_L	0.868	0.32
221_F	390_F	0.867	0.32
7_E	364_E	0.866	0.32
379_K	429_A	0.864	0.32
107_S	110_K	0.863	0.32
94_I	107_S	0.859	0.32
362_F	395_V	0.857	0.32
401_L	411_G	0.854	0.32
221_F	373_F	0.851	0.31
337_P	444_L	0.851	0.31
248_N	254_Q	0.850	0.31
35_E	304_L	0.848	0.31
332_G	338_D	0.846	0.31
386_A	420_L	0.846	0.31
264_H	313_T	0.844	0.31
442_S	449_I	0.843	0.31
384_K	411_G	0.843	0.31
200_K	369_L	0.840	0.31
374_Y	379_K	0.836	0.31
222_L	373_F	0.835	0.31
179_G	358_N	0.835	0.31
243_E	316_R	0.834	0.30
135_L	149_N	0.833	0.30
9_E	108_W	0.830	0.30
177_E	196_Y	0.830	0.30
206_F	223_E	0.829	0.30
29_I	87_Q	0.824	0.30
51_V	118_K	0.818	0.30
113_G	121_K	0.817	0.30
12_I	155_G	0.816	0.30
51_V	319_A	0.816	0.30
337_P	390_F	0.815	0.29
93_E	297_K	0.813	0.29
12_I	16_L	0.812	0.29
238_N	332_G	0.812	0.29
146_N	458_E	0.811	0.29
108_W	180_I	0.810	0.29
245_E	309_Q	0.809	0.29
360_F	399_G	0.806	0.29
15_F	19_L	0.806	0.29
83_T	286_E	0.805	0.29
69_K	125_K	0.805	0.29
136_A	380_E	0.804	0.29
263_I	303_R	0.804	0.29
243_E	254_Q	0.803	0.29
217_Y	308_S	0.803	0.29
264_H	390_F	0.803	0.29
229_M	453_Y	0.801	0.29
228_I	377_G	0.800	0.29
155_G	169_L	0.796	0.28
310_T	377_G	0.792	0.28
395_V	436_I	0.787	0.28
215_K	363_K	0.787	0.28
218_F	229_M	0.785	0.28
393_P	404_L	0.785	0.28
91_L	110_K	0.784	0.28
86_G	94_I	0.784	0.28
222_L	292_W	0.781	0.28
28_A	35_E	0.779	0.28
101_D	111_R	0.777	0.28
93_E	96_N	0.774	0.27
66_E	105_A	0.774	0.27
82_N	100_K	0.772	0.27
372_I	415_L	0.770	0.27
420_L	437_E	0.769	0.27
322_P	351_L	0.769	0.27
170_I	222_L	0.767	0.27
237_I	410_C	0.767	0.27
140_L	143_A	0.764	0.27
346_I	362_F	0.764	0.27
410_C	415_L	0.761	0.27
123_I	137_L	0.760	0.27
313_T	358_N	0.758	0.27
72_E	132_S	0.753	0.26
386_A	396_E	0.752	0.26
366_L	412_A	0.751	0.26
351_L	390_F	0.751	0.26
101_D	143_A	0.749	0.26
51_V	374_Y	0.748	0.26
91_L	382_K	0.748	0.26
200_K	451_L	0.746	0.26
117_I	161_E	0.745	0.26
339_A	430_G	0.745	0.26
67_G	131_S	0.745	0.26
43_E	239_T	0.744	0.26
392_E	432_W	0.744	0.26
52_K	73_S	0.743	0.26
82_N	86_G	0.742	0.26
377_G	390_F	0.742	0.26
217_Y	229_M	0.741	0.26
113_G	118_K	0.740	0.26
283_N	422_S	0.740	0.26
132_S	139_N	0.739	0.26
241_Y	333_K	0.739	0.26
24_S	167_V	0.739	0.26
341_D	344_H	0.737	0.26
62_V	157_I	0.735	0.25
309_Q	372_I	0.734	0.25
27_L	51_V	0.734	0.25
366_L	395_V	0.733	0.25
135_L	139_N	0.732	0.25
19_L	359_N	0.731	0.25
176_S	275_I	0.729	0.25
365_L	450_R	0.728	0.25
257_D	440_A	0.724	0.25
213_S	315_A	0.723	0.25
411_G	435_G	0.720	0.25
21_K	52_K	0.716	0.25
50_Y	376_L	0.714	0.25
218_F	349_H	0.713	0.24
237_I	390_F	0.712	0.24
44_L	315_A	0.712	0.24
23_N	72_E	0.710	0.24
218_F	390_F	0.708	0.24
151_L	156_L	0.705	0.24
360_F	448_D	0.704	0.24
337_P	437_E	0.703	0.24
166_S	188_I	0.702	0.24
72_E	190_S	0.701	0.24
337_P	395_V	0.701	0.24
78_D	82_N	0.700	0.24
309_Q	347_E	0.697	0.24
397_A	412_A	0.696	0.24
381_V	440_A	0.696	0.24
180_I	187_L	0.694	0.24
136_A	144_D	0.693	0.24
435_G	456_N	0.691	0.23
94_I	286_E	0.691	0.23
143_A	194_K	0.690	0.23
422_S	451_L	0.689	0.23
264_H	316_R	0.689	0.23
134_Y	137_L	0.688	0.23
107_S	296_W	0.687	0.23
419_I	422_S	0.685	0.23
82_N	197_K	0.685	0.23
18_D	405_G	0.684	0.23
102_F	112_K	0.682	0.23
71_K	131_S	0.682	0.23
267_F	377_G	0.682	0.23
347_E	441_M	0.677	0.23
403_K	407_V	0.677	0.23
268_S	430_G	0.676	0.23
81_I	123_I	0.675	0.23
225_V	436_I	0.674	0.23
12_I	27_L	0.673	0.23
266_S	305_M	0.673	0.23
143_A	157_I	0.673	0.23
255_P	309_Q	0.672	0.23
130_M	226_K	0.672	0.23
38_V	49_G	0.669	0.23
26_E	111_R	0.667	0.22
232_L	309_Q	0.667	0.22
102_F	188_I	0.666	0.22
245_E	251_L	0.666	0.22
213_S	343_T	0.664	0.22
135_L	157_I	0.663	0.22
272_S	325_P	0.663	0.22
202_N	207_P	0.662	0.22
139_N	157_I	0.662	0.22
18_D	68_R	0.660	0.22
112_K	371_E	0.660	0.22
182_N	381_V	0.659	0.22
133_E	136_A	0.658	0.22
27_L	90_D	0.656	0.22
77_E	156_L	0.654	0.22
56_K	166_S	0.654	0.22
79_I	84_L	0.653	0.22
157_I	172_E	0.652	0.22
401_L	454_S	0.651	0.22
337_P	346_I	0.649	0.22
76_P	453_Y	0.649	0.22
390_F	411_G	0.649	0.22
378_I	384_K	0.647	0.22
46_R	53_T	0.646	0.22
240_G	409_M	0.645	0.21
409_M	420_L	0.644	0.21
301_T	447_S	0.642	0.21
384_K	454_S	0.641	0.21
349_H	442_S	0.641	0.21
270_E	339_A	0.640	0.21
91_L	107_S	0.640	0.21
271_G	407_V	0.639	0.21
167_V	178_I	0.639	0.21
133_E	140_L	0.638	0.21
299_D	302_L	0.635	0.21
160_K	223_E	0.634	0.21
338_D	390_F	0.633	0.21
398_Y	409_M	0.633	0.21
418_E	433_G	0.632	0.21
417_P	437_E	0.630	0.21
215_K	223_E	0.630	0.21
388_F	398_Y	0.630	0.21
103_N	369_L	0.629	0.21
305_M	370_K	0.627	0.21
32_G	157_I	0.626	0.21
32_G	69_K	0.625	0.21
309_Q	330_T	0.625	0.21
82_N	290_K	0.625	0.21
362_F	444_L	0.625	0.21
35_E	43_E	0.625	0.21
327_K	400_Y	0.625	0.21
114_L	126_V	0.623	0.21
264_H	373_F	0.618	0.20
172_E	374_Y	0.617	0.20
73_S	197_K	0.617	0.20
128_T	137_L	0.615	0.20
275_I	314_T	0.615	0.20
337_P	411_G	0.615	0.20
54_E	60_H	0.614	0.20
363_K	403_K	0.614	0.20
322_P	402_E	0.612	0.20
69_K	181_S	0.612	0.20
363_K	399_G	0.612	0.20
228_I	338_D	0.612	0.20
33_I	37_S	0.612	0.20
354_V	388_F	0.611	0.20
71_K	78_D	0.611	0.20
227_D	432_W	0.611	0.20
11_K	167_V	0.610	0.20
40_S	44_L	0.610	0.20
345_L	373_F	0.609	0.20
53_T	230_I	0.609	0.20
11_K	139_N	0.608	0.20
69_K	190_S	0.607	0.20
283_N	359_N	0.607	0.20
54_E	131_S	0.605	0.20
331_L	436_I	0.604	0.20
136_A	140_L	0.603	0.20
372_I	390_F	0.602	0.20
63_L	96_N	0.600	0.20
28_A	117_I	0.598	0.20
228_I	310_T	0.598	0.20
59_K	161_E	0.595	0.19
386_A	417_P	0.594	0.19
417_P	420_L	0.593	0.19
240_G	313_T	0.593	0.19
358_N	435_G	0.591	0.19
412_A	444_L	0.591	0.19
17_K	52_K	0.590	0.19
69_K	138_S	0.590	0.19
248_N	264_H	0.588	0.19
301_T	369_L	0.584	0.19
111_R	210_Y	0.583	0.19
433_G	438_R	0.582	0.19
32_G	122_V	0.581	0.19
283_N	319_A	0.581	0.19
416_R	433_G	0.581	0.19
93_E	171_K	0.579	0.19
49_G	275_I	0.579	0.19
245_E	254_Q	0.578	0.19
73_S	320_S	0.578	0.19
396_E	449_I	0.578	0.19
302_L	327_K	0.577	0.19
384_K	397_A	0.576	0.19
386_A	449_I	0.576	0.19
313_T	316_R	0.575	0.19
145_S	168_E	0.575	0.19
333_K	381_V	0.575	0.19
229_M	352_D	0.574	0.19
218_F	222_L	0.574	0.19
172_E	178_I	0.573	0.19
26_E	135_L	0.572	0.19
403_K	458_E	0.571	0.19
309_Q	373_F	0.571	0.19
277_D	422_S	0.571	0.19
337_P	384_K	0.570	0.18
334_V	347_E	0.570	0.18
263_I	309_Q	0.569	0.18
65_E	195_K	0.569	0.18
42_I	51_V	0.569	0.18
266_S	309_Q	0.568	0.18
254_Q	312_A	0.567	0.18
85_N	88_E	0.566	0.18
255_P	321_R	0.564	0.18
104_I	354_V	0.564	0.18
333_K	406_W	0.563	0.18
44_L	351_L	0.561	0.18
69_K	92_N	0.561	0.18
51_V	55_V	0.560	0.18
178_I	275_I	0.560	0.18
213_S	237_I	0.560	0.18
170_I	373_F	0.560	0.18
337_P	372_I	0.560	0.18
123_I	126_V	0.559	0.18
131_S	178_I	0.559	0.18
35_E	53_T	0.559	0.18
73_S	172_E	0.555	0.18
27_L	55_V	0.554	0.18
247_Y	266_S	0.553	0.18
226_K	338_D	0.553	0.18
237_I	243_E	0.552	0.18
136_A	269_V	0.552	0.18
168_E	195_K	0.551	0.18
330_T	351_L	0.551	0.18
337_P	436_I	0.550	0.18
123_I	127_K	0.550	0.18
67_G	329_F	0.550	0.18
322_P	453_Y	0.549	0.18
309_Q	437_E	0.549	0.18
102_F	231_S	0.548	0.18
94_I	102_F	0.547	0.18
254_Q	383_F	0.547	0.18
179_G	279_D	0.546	0.18
283_N	358_N	0.545	0.18
223_E	227_D	0.545	0.18
117_I	431_A	0.544	0.18
291_F	294_Y	0.544	0.18
388_F	399_G	0.543	0.18
214_K	369_L	0.543	0.18
388_F	419_I	0.543	0.18
334_V	444_L	0.542	0.17
221_F	454_S	0.542	0.17
137_L	140_L	0.541	0.17
11_K	297_K	0.541	0.17
249_F	364_E	0.540	0.17
279_D	283_N	0.540	0.17
308_S	390_F	0.538	0.17
75_L	362_F	0.537	0.17
254_Q	430_G	0.535	0.17
143_A	160_K	0.535	0.17
165_V	187_L	0.535	0.17
135_L	189_I	0.534	0.17
151_L	167_V	0.533	0.17
335_F	349_H	0.532	0.17
80_L	321_R	0.531	0.17
132_S	286_E	0.530	0.17
128_T	331_L	0.530	0.17
46_R	51_V	0.530	0.17
401_L	453_Y	0.529	0.17
224_K	305_M	0.528	0.17
139_N	432_W	0.528	0.17
194_K	314_T	0.527	0.17
267_F	347_E	0.526	0.17
137_L	273_G	0.525	0.17
243_E	248_N	0.525	0.17
254_Q	369_L	0.525	0.17
70_R	232_L	0.524	0.17
283_N	301_T	0.523	0.17
188_I	192_E	0.523	0.17
22_T	82_N	0.522	0.17
237_I	352_D	0.522	0.17
398_Y	401_L	0.521	0.17
384_K	449_I	0.521	0.17
266_S	372_I	0.520	0.17
370_K	428_T	0.519	0.17
237_I	420_L	0.518	0.17
165_V	351_L	0.518	0.17
184_N	260_A	0.518	0.17
72_E	146_N	0.518	0.17
226_K	354_V	0.517	0.17
50_Y	223_E	0.517	0.17
251_L	420_L	0.517	0.17
266_S	332_G	0.517	0.17
254_Q	304_L	0.516	0.17
376_L	397_A	0.515	0.17
83_T	193_W	0.515	0.17
337_P	398_Y	0.513	0.16
409_M	446_I	0.512	0.16
112_K	151_L	0.511	0.16
66_E	104_I	0.511	0.16
198_L	237_I	0.510	0.16
139_N	144_D	0.509	0.16
21_K	168_E	0.509	0.16
40_S	61_Y	0.508	0.16
73_S	124_P	0.508	0.16
247_Y	423_V	0.507	0.16
16_L	22_T	0.506	0.16
159_E	223_E	0.505	0.16
18_D	195_K	0.505	0.16
44_L	411_G	0.503	0.16
218_F	309_Q	0.502	0.16
264_H	395_V	0.501	0.16
244_M	390_F	0.501	0.16
243_E	264_H	0.500	0.16
380_E	446_I	0.500	0.16

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3l4gA	2	0.9915	100	0.389	Contact Map
1b7yA	2	0.5299	100	0.67	Contact Map
2odrC	4	0.5598	100	0.675	Contact Map
2du7A	7	0.6154	100	0.685	Contact Map
2odrD	4	0.5598	100	0.685	Contact Map
2odrA	4	0.5598	100	0.685	Contact Map
2odrB	3	0.5598	100	0.686	Contact Map
2du3A	4	0.6175	100	0.69	Contact Map
4p72C	2	0.5043	100	0.703	Contact Map
3pcoA	2	0.6581	100	0.712	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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