SYFB - SULSO - GREMLIN Contacts

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SYFB - Phenylalanine--tRNA ligase beta subunit

UniProt:	P95960	Sequences: MVTIVLNKYKLLNKIGIGQQKLEDLLFNLKSEIKPVDESNIEIEINADRLDLLSSDGIARAIKGLLEKELGEAKYDITDTEYKLIVDNVRTRPYALAAVIYNAKIDLQELIQFQEKLHSTIGRKRKKVAIGIHDLKKIDSKRIEYREVPLSYKFIPLYEKEELTISEVLEKTEQGKLYGNISISNGVSPAIVQEDGEVLSIPPIINSDKTKLDESTKDLFIDVTGTSFEAVAQTLDIIVSNLAEAGGTIGRVKVIKTDNSFQQSSPLLIHKIQNVREEYANKILGIKISEEEICKHITRMRMNCNVENGIIRVTVPQYRVDIINEIDIVEDIAMSIGYNNLEPSKYISTNYGSYDYLTLLERKMRELSIGAGFVEVFNFVLIKNEKILDSKYVKILNPISEEYNAVRNSLIPILLDFLSKNQHAKFPIRIFETGDVVIYDSSTDTGFRNDKRAAYAIMDNKVSYEDVQAPIHYILKTLGIEVNYKEENNDIFIEGRSASIVYENEKIGVIGEINPDVLIRFGIEYPTVIAELYITEIAKKLNKR	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	544 (526)
Sequences:	4438 (3181)
Seq/√Len:	138.7

ECOLI - SYFB
BACSU - SYFB
HALSA - SYFB
SULSO - SYFB

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
136_K	197_E	5.669	1.00
455_Y	530_A	4.899	1.00
153_K	161_E	3.900	1.00
153_K	163_L	3.675	1.00
418_L	456_A	3.550	1.00
97_A	199_L	3.461	1.00
99_V	135_L	3.365	1.00
133_H	179_G	3.210	1.00
150_L	166_S	3.114	1.00
302_M	322_I	3.029	1.00
485_K	499_S	2.996	1.00
18_G	21_K	2.962	1.00
499_S	506_K	2.812	1.00
159_E	187_V	2.767	1.00
496_R	512_E	2.723	1.00
100_I	202_P	2.718	1.00
281_N	287_K	2.689	1.00
276_R	325_E	2.650	1.00
485_K	501_V	2.632	1.00
139_D	175_G	2.621	1.00
378_N	417_F	2.587	1.00
95_A	133_H	2.576	1.00
168_V	218_D	2.534	1.00
13_N	116_K	2.532	1.00
501_V	506_K	2.510	1.00
384_N	404_N	2.490	1.00
137_K	192_V	2.475	1.00
102_N	256_K	2.403	1.00
279_Y	325_E	2.391	1.00
100_I	255_I	2.330	1.00
16_G	71_G	2.318	1.00
274_N	312_R	2.318	1.00
512_E	526_P	2.302	1.00
296_H	335_S	2.285	1.00
450_D	533_Y	2.265	1.00
411_I	529_I	2.222	1.00
289_S	292_E	2.212	1.00
109_E	113_F	2.174	1.00
277_E	293_I	2.171	1.00
156_P	162_E	2.167	1.00
373_F	470_P	2.151	1.00
148_V	164_T	2.126	1.00
178_Y	189_P	2.124	1.00
280_A	293_I	2.115	1.00
376_V	430_I	2.092	1.00
111_I	115_E	2.059	1.00
96_L	242_L	2.044	1.00
295_K	299_R	2.033	1.00
487_E	499_S	2.028	1.00
275_V	328_I	2.019	1.00
505_E	536_E	2.011	1.00
101_Y	197_E	2.006	1.00
292_E	295_K	1.985	1.00
108_Q	114_Q	1.972	1.00
384_N	394_K	1.967	1.00
101_Y	256_K	1.955	1.00
236_D	317_Q	1.953	1.00
272_I	314_T	1.952	1.00
95_A	179_G	1.951	1.00
138_I	178_Y	1.940	1.00
165_I	218_D	1.934	1.00
155_I	161_E	1.929	1.00
283_I	326_I	1.917	1.00
98_A	243_A	1.902	1.00
94_Y	263_Q	1.896	1.00
87_D	144_E	1.893	1.00
146_R	152_Y	1.893	1.00
272_I	312_R	1.892	1.00
313_V	328_I	1.887	1.00
20_Q	24_D	1.879	1.00
247_G	251_R	1.869	1.00
91_T	147_E	1.864	1.00
274_N	310_I	1.857	1.00
130_I	245_A	1.841	1.00
376_V	417_F	1.822	1.00
284_L	333_A	1.810	1.00
508_G	532_L	1.750	1.00
386_K	416_D	1.746	1.00
275_V	280_A	1.707	1.00
281_N	286_I	1.705	1.00
502_Y	507_I	1.699	1.00
376_V	414_L	1.699	1.00
29_L	65_L	1.683	1.00
154_F	180_N	1.680	1.00
140_S	174_Q	1.672	1.00
146_R	172_T	1.671	1.00
294_C	298_T	1.663	1.00
494_E	514_N	1.661	1.00
173_E	176_K	1.653	1.00
168_V	219_L	1.627	1.00
467_V	510_I	1.625	1.00
303_N	314_T	1.624	1.00
139_D	176_K	1.617	1.00
278_E	309_G	1.606	1.00
501_V	504_N	1.600	1.00
22_L	62_I	1.590	1.00
368_S	453_A	1.581	1.00
114_Q	124_K	1.568	1.00
246_G	257_T	1.566	1.00
88_N	147_E	1.566	1.00
440_D	448_R	1.564	1.00
168_V	215_S	1.561	1.00
409_S	412_P	1.557	1.00
369_I	431_F	1.552	1.00
471_I	475_L	1.551	1.00
279_Y	329_V	1.547	1.00
315_V	322_I	1.541	1.00
277_E	290_E	1.540	1.00
475_L	482_V	1.537	1.00
216_T	226_T	1.519	1.00
234_T	317_Q	1.515	1.00
457_I	467_V	1.496	1.00
118_H	124_K	1.490	1.00
25_L	66_L	1.487	1.00
471_I	530_A	1.484	1.00
113_F	252_V	1.477	1.00
364_M	534_I	1.477	1.00
82_Y	199_L	1.462	1.00
172_T	177_L	1.462	1.00
273_Q	322_I	1.445	1.00
100_I	249_I	1.444	1.00
128_V	249_I	1.439	1.00
512_E	528_V	1.438	1.00
493_I	515_P	1.435	1.00
249_I	255_I	1.429	1.00
222_D	227_S	1.429	1.00
417_F	430_I	1.427	1.00
430_I	456_A	1.424	1.00
176_K	188_S	1.424	1.00
130_I	202_P	1.424	1.00
492_F	509_V	1.423	1.00
135_L	199_L	1.417	1.00
307_E	310_I	1.416	1.00
492_F	497_S	1.412	1.00
7_N	38_E	1.411	1.00
276_R	279_Y	1.394	1.00
60_R	318_Y	1.386	1.00
8_K	19_Q	1.386	1.00
43_I	58_I	1.375	1.00
96_L	239_V	1.374	1.00
19_Q	39_S	1.370	1.00
294_C	311_I	1.365	1.00
298_T	304_C	1.363	1.00
414_L	454_A	1.361	1.00
67_E	295_K	1.359	1.00
419_S	423_H	1.356	1.00
305_N	312_R	1.355	1.00
85_I	144_E	1.353	1.00
122_G	224_T	1.349	1.00
493_I	514_N	1.346	1.00
63_K	70_L	1.345	1.00
15_I	62_I	1.345	1.00
277_E	311_I	1.345	1.00
184_S	223_V	1.343	1.00
114_Q	118_H	1.333	1.00
292_E	340_N	1.330	1.00
279_Y	282_K	1.329	1.00
183_I	215_S	1.320	1.00
452_R	531_E	1.320	1.00
433_T	534_I	1.315	1.00
354_Y	362_R	1.315	1.00
155_I	187_V	1.308	1.00
297_I	328_I	1.306	1.00
492_F	529_I	1.302	1.00
483_N	504_N	1.302	1.00
169_L	181_I	1.299	1.00
414_L	456_A	1.296	1.00
371_A	473_Y	1.296	1.00
283_I	329_V	1.296	1.00
355_D	358_T	1.289	1.00
82_Y	138_I	1.288	1.00
302_M	313_V	1.284	1.00
144_E	174_Q	1.281	1.00
305_N	314_T	1.281	1.00
31_S	52_L	1.270	1.00
96_L	238_I	1.268	1.00
105_I	127_K	1.268	1.00
272_I	315_V	1.259	1.00
455_Y	467_V	1.258	1.00
19_Q	23_E	1.256	1.00
294_C	306_V	1.255	1.00
165_I	168_V	1.254	1.00
250_G	257_T	1.248	1.00
93_P	206_N	1.248	1.00
148_V	152_Y	1.244	1.00
28_N	339_N	1.243	1.00
8_K	12_L	1.239	1.00
91_T	211_K	1.238	1.00
32_E	44_E	1.232	1.00
288_I	293_I	1.228	1.00
394_K	405_A	1.228	1.00
132_I	202_P	1.224	1.00
415_L	456_A	1.220	1.00
336_I	340_N	1.209	1.00
95_A	143_I	1.201	1.00
302_M	315_V	1.199	1.00
239_V	243_A	1.190	1.00
271_K	315_V	1.190	1.00
280_A	332_I	1.188	1.00
373_F	457_I	1.186	1.00
127_K	253_K	1.179	1.00
98_A	246_G	1.175	1.00
23_E	41_I	1.174	0.99
63_K	69_E	1.172	0.99
304_C	311_I	1.171	0.99
111_I	114_Q	1.166	0.99
471_I	500_I	1.166	0.99
104_K	196_G	1.166	0.99
367_L	473_Y	1.163	0.99
244_E	248_T	1.162	0.99
225_G	229_E	1.158	0.99
246_G	250_G	1.156	0.99
25_L	65_L	1.149	0.99
115_E	118_H	1.146	0.99
140_S	173_E	1.145	0.99
533_Y	536_E	1.143	0.99
180_N	219_L	1.140	0.99
183_I	212_L	1.140	0.99
170_E	177_L	1.137	0.99
21_K	24_D	1.135	0.99
179_G	225_G	1.132	0.99
410_L	413_I	1.124	0.99
364_M	474_I	1.123	0.99
130_I	225_G	1.121	0.99
102_N	197_E	1.121	0.99
436_V	452_R	1.119	0.99
45_I	53_L	1.119	0.99
452_R	533_Y	1.118	0.99
150_L	163_L	1.116	0.99
84_L	97_A	1.109	0.99
422_Q	525_Y	1.107	0.99
292_E	336_I	1.107	0.99
67_E	299_R	1.097	0.99
361_E	451_K	1.092	0.99
294_C	304_C	1.091	0.99
471_I	510_I	1.091	0.99
222_D	231_V	1.090	0.99
451_K	535_T	1.088	0.99
279_Y	283_I	1.087	0.99
208_D	211_K	1.086	0.99
101_Y	258_D	1.086	0.99
105_I	128_V	1.077	0.99
275_V	329_V	1.071	0.99
500_I	508_G	1.069	0.99
127_K	252_V	1.067	0.99
211_K	215_S	1.067	0.99
202_P	249_I	1.066	0.99
484_Y	500_I	1.061	0.99
103_A	128_V	1.060	0.99
293_I	332_I	1.060	0.99
278_E	282_K	1.060	0.99
494_E	515_P	1.059	0.99
298_T	303_N	1.057	0.99
31_S	43_I	1.056	0.99
143_I	179_G	1.054	0.99
53_L	227_S	1.053	0.99
325_E	329_V	1.052	0.99
373_F	455_Y	1.052	0.99
227_S	231_V	1.051	0.99
147_E	167_E	1.045	0.99
146_R	154_F	1.044	0.99
202_P	245_A	1.042	0.99
326_I	329_V	1.041	0.99
137_K	194_E	1.041	0.99
162_E	221_I	1.035	0.99
433_T	453_A	1.035	0.99
17_I	66_L	1.034	0.99
151_S	163_L	1.032	0.99
9_Y	12_L	1.031	0.99
150_L	165_I	1.030	0.99
109_E	114_Q	1.030	0.99
50_L	320_V	1.026	0.99
295_K	298_T	1.021	0.99
292_E	296_H	1.020	0.99
271_K	323_I	1.019	0.99
467_V	530_A	1.018	0.99
516_D	520_R	1.008	0.98
333_A	338_Y	1.005	0.98
136_K	196_G	1.003	0.98
204_I	242_L	0.994	0.98
496_R	528_V	0.994	0.98
17_I	22_L	0.991	0.98
135_L	197_E	0.990	0.98
291_E	295_K	0.985	0.98
455_Y	471_I	0.982	0.98
265_S	268_L	0.976	0.98
296_H	336_I	0.976	0.98
95_A	207_S	0.974	0.98
517_V	520_R	0.973	0.98
384_N	388_L	0.971	0.98
171_K	207_S	0.967	0.98
91_T	208_D	0.966	0.98
286_I	342_E	0.966	0.98
143_I	178_Y	0.964	0.98
367_L	477_T	0.956	0.98
483_N	501_V	0.955	0.98
415_L	513_I	0.955	0.98
29_L	335_S	0.955	0.98
489_N	509_V	0.954	0.98
518_L	523_I	0.947	0.98
108_Q	127_K	0.947	0.98
86_V	89_V	0.947	0.98
371_A	470_P	0.944	0.98
392_Y	408_N	0.944	0.98
206_N	209_K	0.943	0.98
373_F	429_R	0.943	0.98
158_Y	162_E	0.941	0.98
438_I	450_D	0.941	0.98
475_L	480_I	0.938	0.98
302_M	331_D	0.936	0.97
101_Y	135_L	0.933	0.97
365_R	433_T	0.932	0.97
290_E	306_V	0.931	0.97
276_R	309_G	0.931	0.97
270_H	303_N	0.929	0.97
191_I	198_V	0.926	0.97
30_K	52_L	0.924	0.97
274_N	307_E	0.923	0.97
360_L	538_A	0.922	0.97
102_N	196_G	0.921	0.97
290_E	311_I	0.921	0.97
64_G	335_S	0.920	0.97
86_V	93_P	0.919	0.97
131_G	185_N	0.915	0.97
465_E	468_Q	0.909	0.97
75_Y	247_G	0.906	0.97
288_I	336_I	0.906	0.97
333_A	341_L	0.905	0.97
167_E	218_D	0.905	0.97
24_D	28_N	0.904	0.97
187_V	192_V	0.903	0.97
468_Q	472_H	0.902	0.97
187_V	190_A	0.902	0.97
381_L	406_V	0.901	0.97
290_E	309_G	0.893	0.97
513_I	518_L	0.887	0.97
7_N	55_S	0.886	0.97
513_I	529_I	0.885	0.96
56_D	72_E	0.884	0.96
178_Y	188_S	0.884	0.96
457_I	470_P	0.883	0.96
83_K	141_K	0.881	0.96
154_F	172_T	0.881	0.96
87_D	149_P	0.877	0.96
487_E	497_S	0.875	0.96
34_K	37_D	0.875	0.96
250_G	253_K	0.873	0.96
26_L	58_I	0.869	0.96
506_K	509_V	0.863	0.96
168_V	180_N	0.858	0.96
460_N	466_D	0.857	0.96
136_K	194_E	0.854	0.96
456_A	529_I	0.853	0.96
483_N	503_E	0.850	0.96
453_A	530_A	0.850	0.96
413_I	434_G	0.849	0.96
361_E	433_T	0.848	0.96
301_R	318_Y	0.846	0.95
202_P	246_G	0.845	0.95
435_D	449_N	0.844	0.95
154_F	177_L	0.844	0.95
164_T	170_E	0.841	0.95
146_R	170_E	0.838	0.95
469_A	472_H	0.837	0.95
179_G	207_S	0.836	0.95
462_V	466_D	0.836	0.95
73_A	244_E	0.836	0.95
499_S	509_V	0.835	0.95
191_I	195_D	0.831	0.95
64_G	300_M	0.830	0.95
416_D	420_K	0.822	0.95
280_A	329_V	0.821	0.95
415_L	521_F	0.820	0.95
489_N	492_F	0.820	0.95
472_H	484_Y	0.818	0.95
143_I	207_S	0.818	0.95
382_I	386_K	0.818	0.95
33_I	43_I	0.815	0.94
31_S	45_I	0.812	0.94
249_I	252_V	0.806	0.94
134_D	137_K	0.802	0.94
76_D	247_G	0.802	0.94
422_Q	458_M	0.801	0.94
130_I	204_I	0.798	0.94
236_D	265_S	0.798	0.94
364_M	453_A	0.797	0.94
95_A	204_I	0.796	0.94
279_Y	326_I	0.794	0.94
244_E	247_G	0.792	0.94
55_S	120_T	0.792	0.94
273_Q	313_V	0.792	0.94
31_S	44_E	0.791	0.94
387_I	392_Y	0.790	0.93
354_Y	358_T	0.790	0.93
7_N	120_T	0.789	0.93
207_S	226_T	0.788	0.93
23_E	33_I	0.788	0.93
56_D	73_A	0.784	0.93
357_L	535_T	0.784	0.93
52_L	61_A	0.784	0.93
322_I	328_I	0.783	0.93
290_E	294_C	0.781	0.93
146_R	149_P	0.778	0.93
143_I	199_L	0.775	0.93
387_I	408_N	0.772	0.93
154_F	170_E	0.770	0.93
277_E	310_I	0.770	0.93
6_L	58_I	0.769	0.93
293_I	329_V	0.767	0.92
21_K	25_L	0.764	0.92
206_N	233_Q	0.763	0.92
162_E	190_A	0.763	0.92
247_G	250_G	0.761	0.92
363_K	366_E	0.760	0.92
516_D	519_I	0.758	0.92
60_R	397_N	0.758	0.92
152_Y	172_T	0.756	0.92
16_G	68_K	0.756	0.92
138_I	199_L	0.755	0.92
136_K	192_V	0.755	0.92
407_R	434_G	0.753	0.92
306_V	309_G	0.752	0.92
276_R	310_I	0.752	0.92
272_I	305_N	0.752	0.92
277_E	281_N	0.751	0.92
418_L	458_M	0.748	0.92
216_T	222_D	0.747	0.91
496_R	526_P	0.747	0.91
518_L	526_P	0.746	0.91
368_S	474_I	0.746	0.91
440_D	446_G	0.745	0.91
82_Y	97_A	0.744	0.91
413_I	437_V	0.742	0.91
458_M	525_Y	0.740	0.91
10_K	116_K	0.740	0.91
112_Q	252_V	0.738	0.91
8_K	41_I	0.737	0.91
270_H	317_Q	0.736	0.91
94_Y	265_S	0.736	0.91
170_E	180_N	0.734	0.91
239_V	262_Q	0.734	0.91
144_E	147_E	0.734	0.91
236_D	270_H	0.731	0.91
368_S	455_Y	0.730	0.91
99_V	199_L	0.730	0.91
420_K	424_A	0.726	0.90
33_I	41_I	0.725	0.90
149_P	152_Y	0.723	0.90
9_Y	37_D	0.723	0.90
407_R	432_E	0.722	0.90
156_P	184_S	0.720	0.90
137_K	188_S	0.719	0.90
523_I	527_T	0.719	0.90
401_E	404_N	0.718	0.90
7_N	119_S	0.717	0.90
365_R	375_E	0.714	0.90
505_E	533_Y	0.714	0.90
169_L	207_S	0.712	0.89
356_Y	360_L	0.710	0.89
243_A	247_G	0.710	0.89
281_N	290_E	0.709	0.89
95_A	171_K	0.709	0.89
109_E	127_K	0.708	0.89
87_D	146_R	0.707	0.89
88_N	91_T	0.705	0.89
67_E	292_E	0.705	0.89
263_Q	266_P	0.703	0.89
392_Y	405_A	0.702	0.89
439_Y	447_F	0.702	0.89
464_Y	498_A	0.702	0.89
385_E	388_L	0.701	0.89
382_I	413_I	0.700	0.89
132_I	179_G	0.698	0.88
193_Q	196_G	0.697	0.88
384_N	405_A	0.696	0.88
366_E	369_I	0.696	0.88
482_V	502_Y	0.694	0.88
367_L	370_G	0.693	0.88
131_G	157_L	0.693	0.88
83_K	86_V	0.692	0.88
60_R	70_L	0.691	0.88
25_L	28_N	0.690	0.88
180_N	183_I	0.689	0.88
70_L	73_A	0.687	0.88
108_Q	113_F	0.685	0.88
82_Y	141_K	0.685	0.88
270_H	314_T	0.685	0.88
103_A	197_E	0.684	0.87
139_D	173_E	0.683	0.87
275_V	297_I	0.682	0.87
117_L	122_G	0.680	0.87
457_I	462_V	0.679	0.87
17_I	21_K	0.676	0.87
435_D	451_K	0.675	0.87
391_K	439_Y	0.674	0.87
155_I	188_S	0.674	0.87
9_Y	38_E	0.670	0.86
47_A	53_L	0.669	0.86
136_K	218_D	0.669	0.86
155_I	159_E	0.669	0.86
105_I	126_K	0.668	0.86
439_Y	446_G	0.668	0.86
30_K	46_N	0.667	0.86
465_E	472_H	0.666	0.86
237_I	240_S	0.665	0.86
23_E	27_F	0.664	0.86
382_I	403_Y	0.663	0.86
19_Q	41_I	0.662	0.86
507_I	536_E	0.662	0.86
138_I	143_I	0.661	0.86
206_N	238_I	0.660	0.86
288_I	296_H	0.660	0.86
315_V	323_I	0.659	0.85
152_Y	170_E	0.657	0.85
484_Y	510_I	0.653	0.85
113_F	116_K	0.653	0.85
406_V	437_V	0.652	0.85
284_L	341_L	0.650	0.85
418_L	428_I	0.650	0.85
77_I	243_A	0.650	0.85
204_I	238_I	0.649	0.85
181_I	203_P	0.648	0.84
222_D	230_A	0.646	0.84
413_I	417_F	0.646	0.84
512_E	518_L	0.645	0.84
487_E	506_K	0.645	0.84
156_P	190_A	0.645	0.84
95_A	225_G	0.643	0.84
48_D	51_D	0.643	0.84
438_I	448_R	0.642	0.84
157_L	185_N	0.642	0.84
375_E	431_F	0.642	0.84
84_L	199_L	0.640	0.84
38_E	119_S	0.639	0.84
31_S	58_I	0.639	0.84
215_S	219_L	0.639	0.84
81_E	256_K	0.638	0.84
104_K	193_Q	0.637	0.83
203_P	207_S	0.636	0.83
473_Y	477_T	0.636	0.83
109_E	124_K	0.635	0.83
22_L	41_I	0.635	0.83
249_I	253_K	0.634	0.83
206_N	235_L	0.633	0.83
275_V	293_I	0.632	0.83
14_K	56_D	0.632	0.83
383_K	386_K	0.631	0.83
276_R	329_V	0.631	0.83
300_M	335_S	0.630	0.83
31_S	61_A	0.630	0.83
277_E	280_A	0.630	0.83
84_L	262_Q	0.627	0.83
14_K	55_S	0.626	0.82
90_R	208_D	0.626	0.82
181_I	205_I	0.625	0.82
57_G	60_R	0.625	0.82
32_E	43_I	0.624	0.82
82_Y	86_V	0.622	0.82
276_R	326_I	0.622	0.82
275_V	311_I	0.621	0.82
181_I	204_I	0.621	0.82
418_L	527_T	0.620	0.82
154_F	186_G	0.620	0.82
453_A	471_I	0.620	0.82
149_P	153_K	0.620	0.82
184_S	221_I	0.619	0.82
482_V	508_G	0.618	0.82
394_K	404_N	0.617	0.82
58_I	61_A	0.616	0.81
141_K	174_Q	0.616	0.81
393_V	447_F	0.616	0.81
44_E	227_S	0.614	0.81
457_I	466_D	0.614	0.81
415_L	527_T	0.612	0.81
81_E	257_T	0.612	0.81
524_E	527_T	0.612	0.81
61_A	331_D	0.611	0.81
283_I	325_E	0.610	0.81
44_E	50_L	0.609	0.81
296_H	300_M	0.609	0.81
291_E	306_V	0.608	0.81
422_Q	524_E	0.607	0.80
106_D	254_V	0.607	0.80
15_I	63_K	0.606	0.80
147_E	211_K	0.605	0.80
284_L	329_V	0.604	0.80
433_T	451_K	0.604	0.80
498_A	515_P	0.602	0.80
488_N	497_S	0.602	0.80
361_E	365_R	0.600	0.80
482_V	507_I	0.599	0.80
156_P	160_K	0.599	0.80
493_I	498_A	0.597	0.79
112_Q	248_T	0.596	0.79
8_K	39_S	0.596	0.79
20_Q	23_E	0.596	0.79
397_N	403_Y	0.596	0.79
56_D	70_L	0.595	0.79
135_L	141_K	0.595	0.79
382_I	412_P	0.595	0.79
455_Y	470_P	0.594	0.79
379_F	403_Y	0.594	0.79
281_N	288_I	0.594	0.79
395_I	406_V	0.594	0.79
100_I	198_V	0.593	0.79
26_L	31_S	0.590	0.79
131_G	184_S	0.590	0.79
492_F	511_G	0.590	0.79
181_I	212_L	0.589	0.78
34_K	40_N	0.589	0.78
411_I	492_F	0.589	0.78
207_S	229_E	0.587	0.78
195_D	198_V	0.586	0.78
403_Y	416_D	0.586	0.78
105_I	193_Q	0.585	0.78
373_F	467_V	0.584	0.78
6_L	55_S	0.582	0.78
137_K	189_P	0.582	0.78
359_L	363_K	0.582	0.78
102_N	254_V	0.579	0.77
144_E	172_T	0.579	0.77
428_I	458_M	0.578	0.77
45_I	52_L	0.578	0.77
415_L	523_I	0.577	0.77
495_G	514_N	0.576	0.77
132_I	143_I	0.576	0.77
98_A	260_S	0.576	0.77
269_I	272_I	0.575	0.77
26_L	33_I	0.574	0.77
419_S	523_I	0.574	0.77
26_L	43_I	0.574	0.77
489_N	499_S	0.572	0.76
225_G	231_V	0.572	0.76
363_K	477_T	0.571	0.76
95_A	130_I	0.571	0.76
492_F	510_I	0.569	0.76
52_L	58_I	0.569	0.76
94_Y	264_S	0.569	0.76
185_N	203_P	0.569	0.76
449_N	456_A	0.569	0.76
464_Y	467_V	0.567	0.76
27_F	32_E	0.566	0.76
364_M	478_L	0.565	0.76
105_I	108_Q	0.565	0.76
44_E	47_A	0.564	0.75
363_K	367_L	0.564	0.75
286_I	341_L	0.564	0.75
92_R	125_R	0.564	0.75
52_L	381_L	0.564	0.75
489_N	506_K	0.564	0.75
480_I	532_L	0.563	0.75
497_S	509_V	0.563	0.75
100_I	197_E	0.562	0.75
437_V	449_N	0.562	0.75
173_E	178_Y	0.562	0.75
61_A	64_G	0.561	0.75
123_R	157_L	0.561	0.75
380_V	437_V	0.561	0.75
355_D	362_R	0.561	0.75
457_I	528_V	0.560	0.75
453_A	474_I	0.559	0.75
276_R	280_A	0.559	0.75
9_Y	35_P	0.559	0.75
138_I	141_K	0.559	0.75
243_A	246_G	0.558	0.75
500_I	510_I	0.558	0.75
216_T	221_I	0.557	0.75
72_E	301_R	0.557	0.75
180_N	211_K	0.557	0.75
46_N	52_L	0.556	0.74
139_D	174_Q	0.556	0.74
86_V	264_S	0.555	0.74
418_L	523_I	0.555	0.74
532_L	537_I	0.555	0.74
212_L	225_G	0.554	0.74
376_V	456_A	0.552	0.74
55_S	58_I	0.551	0.74
263_Q	267_L	0.550	0.74
82_Y	262_Q	0.549	0.73
126_K	193_Q	0.548	0.73
185_N	205_I	0.548	0.73
11_L	32_E	0.548	0.73
500_I	532_L	0.548	0.73
56_D	240_S	0.548	0.73
42_E	45_I	0.546	0.73
400_S	404_N	0.546	0.73
50_L	227_S	0.544	0.73
128_V	132_I	0.543	0.73
493_I	496_R	0.543	0.73
149_P	166_S	0.543	0.73
241_N	245_A	0.543	0.73
63_K	68_K	0.542	0.73
493_I	512_E	0.541	0.72
76_D	80_T	0.541	0.72
463_S	466_D	0.541	0.72
378_N	413_I	0.540	0.72
67_E	298_T	0.540	0.72
74_K	240_S	0.540	0.72
322_I	335_S	0.540	0.72
465_E	469_A	0.539	0.72
76_D	79_D	0.539	0.72
190_A	224_T	0.538	0.72
358_T	362_R	0.538	0.72
390_S	408_N	0.538	0.72
86_V	265_S	0.535	0.72
125_R	128_V	0.534	0.71
243_A	261_F	0.534	0.71
128_V	198_V	0.534	0.71
441_S	446_G	0.534	0.71
48_D	53_L	0.534	0.71
289_S	295_K	0.532	0.71
228_F	231_V	0.532	0.71
286_I	336_I	0.532	0.71
12_L	68_K	0.531	0.71
103_A	109_E	0.531	0.71
152_Y	164_T	0.530	0.71
245_A	248_T	0.529	0.71
164_T	180_N	0.528	0.71
30_K	53_L	0.528	0.71
131_G	189_P	0.528	0.71
270_H	315_V	0.526	0.70
70_L	318_Y	0.526	0.70
231_V	234_T	0.525	0.70
99_V	197_E	0.525	0.70
82_Y	135_L	0.525	0.70
129_A	185_N	0.525	0.70
376_V	428_I	0.524	0.70
133_H	207_S	0.523	0.70
495_G	511_G	0.523	0.70
62_I	66_L	0.523	0.70
84_L	95_A	0.523	0.70
130_I	207_S	0.523	0.70
15_I	68_K	0.523	0.70
297_I	311_I	0.522	0.70
380_V	406_V	0.522	0.70
395_I	403_Y	0.520	0.69
138_I	189_P	0.520	0.69
74_K	247_G	0.519	0.69
162_E	224_T	0.519	0.69
484_Y	508_G	0.519	0.69
45_I	50_L	0.519	0.69
275_V	278_E	0.518	0.69
439_Y	442_S	0.518	0.69
97_A	143_I	0.518	0.69
381_L	399_I	0.518	0.69
30_K	45_I	0.518	0.69
234_T	237_I	0.518	0.69
453_A	532_L	0.518	0.69
237_I	241_N	0.517	0.69
91_T	169_L	0.517	0.69
27_F	33_I	0.517	0.69
303_N	315_V	0.517	0.69
11_L	59_A	0.516	0.69
17_I	68_K	0.516	0.69
434_G	437_V	0.516	0.69
162_E	180_N	0.515	0.69
250_G	254_V	0.515	0.69
37_D	40_N	0.514	0.69
48_D	330_E	0.514	0.69
45_I	227_S	0.514	0.69
487_E	501_V	0.513	0.68
125_R	190_A	0.513	0.68
114_Q	117_L	0.513	0.68
29_L	62_I	0.513	0.68
381_L	403_Y	0.513	0.68
463_S	528_V	0.512	0.68
84_L	393_V	0.511	0.68
92_R	205_I	0.511	0.68
204_I	241_N	0.510	0.68
385_E	520_R	0.510	0.68
130_I	242_L	0.509	0.68
159_E	190_A	0.509	0.68
367_L	474_I	0.508	0.68
104_K	254_V	0.507	0.68
518_L	527_T	0.507	0.68
22_L	26_L	0.506	0.67
297_I	332_I	0.505	0.67
400_S	403_Y	0.505	0.67
453_A	534_I	0.505	0.67
16_G	69_E	0.503	0.67
535_T	538_A	0.503	0.67
109_E	117_L	0.502	0.67
30_K	47_A	0.502	0.67
129_A	205_I	0.501	0.67
167_E	219_L	0.501	0.67
54_S	57_G	0.501	0.67
360_L	537_I	0.500	0.66
534_I	537_I	0.500	0.66
341_L	344_S	0.500	0.66

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2rhqB	2	0.9853	100	0.129	Contact Map
4p72A	2	0.9835	100	0.133	Contact Map
3pcoB	2	0.9871	100	0.136	Contact Map
1b7yB	2	0.9651	100	0.148	Contact Map
3l4gB	2	0.932	100	0.238	Contact Map
2cxiA	3	0.5588	100	0.546	Contact Map
2rhqA	2	0.3934	100	0.704	Contact Map
3icaA	2	0.3401	100	0.735	Contact Map
3ig2A	4	0.3364	100	0.737	Contact Map
2du3A	4	0.4265	100	0.759	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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