HELX - SULSO - GREMLIN Contacts

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HELX - Uncharacterized ATP-dependent helicase SSO0112

UniProt:	P95949	Sequences: MSNTYFYSDEEIYNLLRPYVAKWFRQKYTTFTPPQRAAIPLIKQNYNVLVSSPTGSGKTLAAFLGILDSLFELGDNNELEDKVYAIYISPLRALNNDMQRNLLEPLNELRQVNSKLPDVRVGIRTSDTTPYEKQKMLKKPPHILITTPESFGISITSPKFSQKLTDVKWIIVDEIHELANSKRGAYLSAMLELFRNLITKKEFVRIGLSATVSPLEEVAQFLVGKDREYRIVDARFVKPVDIKVISPVKDLVHSSESEVDKGIYKTILNEVKKHRTTLIFTNTRHATERVAYKLRKLAENEKVFDVDAIEAHHSSLSRDVRLDVEEKLKKGILKVVVSSTSLELGIDIGYIDLVILLSSPKSVSRLLQRIGRAGHHIRSISKGRVIVVDRDDLVECSVLAKLARDRKIDSIHIPKNPLDVLSQIIVSASLISPIDRDDLFKILRRSYNFSDLSESDYSLVLRYLSGDFFGVELKNVYAKIRIKEEKIIYPKKGSRLIFYTNSGTIPDEAMISVVTENNRYVGNLEEEFVEILSPGDIFVLSGRTYEFIGSKGSKVIVKEAMGQRPTVPSWFSEMLPLAYESALEIGKFRREIAEMIKKGVTHNEIIESISKEYEIDKHASMSIYTYILEQYLFTNGKVPSDNLILIEIYDDEEGIRNYIFHALYGRRALDALSRAFAYVVSEELDTDVRVSVTDNGFALSVKRDVPFDYNIKSLFEKITPDNVYDIVTRAVMRTEMLKRRFRHCAERSFMILRRYKGRETNLERRELNSEILLKAIREIGNFPVMKETIREILEDHMDILRAKEILKKIASQEIKVDVFGPTNIPSPFSHSIILKGHSDVVLAEDRRELLKKLHERVVEFLRQKGVNIELEYTSV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	875 (795)
Sequences:	1475 (875)
Seq/√Len:	31.0

ECOLI - LHR
HALSA - Q9HQA5
SULSO - HELX Q97ZF3 Q980C0

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
376_H	379_S	6.031	1.00
454_E	458_S	5.748	1.00
416_N	456_D	5.494	1.00
440_F	454_E	5.019	1.00
374_G	377_I	4.726	1.00
375_H	378_R	4.665	1.00
590_R	641_D	4.489	1.00
170_I	191_L	4.437	1.00
106_L	121_V	4.321	1.00
375_H	379_S	4.240	1.00
805_I	814_I	4.047	1.00
46_Y	230_R	4.033	1.00
440_F	457_Y	3.888	1.00
437_D	454_E	3.886	1.00
196_N	445_R	3.877	1.00
195_R	205_R	3.839	1.00
374_G	378_R	3.825	1.00
435_D	438_D	3.713	1.00
278_L	351_I	3.693	1.00
440_F	444_R	3.564	1.00
724_Y	803_K	3.467	1.00
453_S	456_D	3.415	1.00
185_A	449_F	3.394	1.00
447_Y	450_S	3.363	1.00
808_K	813_E	3.318	1.00
374_G	379_S	3.305	1.00
134_Q	138_K	3.247	1.00
425_I	439_L	3.247	1.00
271_V	335_V	3.235	1.00
720_P	810_A	3.131	1.00
643_L	815_K	3.122	1.00
511_I	555_V	3.110	1.00
244_V	247_P	3.100	1.00
21_A	25_R	3.078	1.00
546_E	558_K	3.061	1.00
164_L	167_V	3.055	1.00
427_S	498_F	2.974	1.00
267_I	355_I	2.904	1.00
172_V	222_L	2.862	1.00
162_Q	165_T	2.844	1.00
274_H	382_K	2.837	1.00
267_I	357_L	2.833	1.00
644_I	660_F	2.825	1.00
240_V	247_P	2.792	1.00
548_I	558_K	2.751	1.00
223_V	229_Y	2.744	1.00
278_L	338_S	2.724	1.00
66_I	171_I	2.629	1.00
129_T	132_E	2.610	1.00
640_S	643_L	2.596	1.00
45_N	204_V	2.570	1.00
454_E	457_Y	2.540	1.00
217_E	220_Q	2.524	1.00
415_K	450_S	2.519	0.99
268_L	297_L	2.501	0.99
175_I	218_V	2.485	0.99
122_G	132_E	2.441	0.99
216_E	231_I	2.417	0.99
456_D	786_K	2.406	0.99
120_R	142_H	2.404	0.99
244_V	250_D	2.396	0.99
464_L	480_I	2.392	0.99
247_P	253_H	2.391	0.99
326_E	330_K	2.388	0.99
196_N	438_D	2.377	0.99
110_R	118_D	2.369	0.99
318_R	322_L	2.314	0.99
485_E	489_Y	2.279	0.99
189_A	443_L	2.278	0.99
421_L	443_L	2.277	0.99
583_L	808_K	2.274	0.99
358_S	388_V	2.273	0.99
359_S	395_E	2.231	0.99
660_F	697_F	2.227	0.99
84_Y	142_H	2.226	0.99
327_K	332_I	2.225	0.99
242_I	247_P	2.221	0.99
486_K	489_Y	2.209	0.99
51_S	215_L	2.183	0.99
415_K	451_D	2.180	0.99
82_K	166_D	2.176	0.98
290_V	357_L	2.174	0.98
244_V	253_H	2.153	0.98
422_S	460_V	2.138	0.98
198_I	203_F	2.129	0.98
790_R	794_E	2.111	0.98
241_D	247_P	2.110	0.98
122_G	141_P	2.097	0.98
99_Q	103_L	2.078	0.98
131_Y	135_K	2.073	0.98
593_A	631_Y	2.039	0.98
170_I	194_F	2.013	0.97
195_R	203_F	2.002	0.97
270_E	353_L	1.993	0.97
587_K	591_E	1.985	0.97
385_V	396_C	1.980	0.97
66_I	85_A	1.975	0.97
247_P	251_L	1.963	0.97
86_I	167_V	1.954	0.97
196_N	442_I	1.943	0.97
648_I	821_P	1.931	0.97
195_R	202_E	1.920	0.97
266_T	269_N	1.900	0.96
664_Y	805_I	1.892	0.96
238_K	247_P	1.887	0.96
240_V	244_V	1.876	0.96
416_N	453_S	1.865	0.96
33_P	37_A	1.863	0.96
50_V	61_A	1.858	0.96
218_V	221_F	1.856	0.96
279_I	646_I	1.855	0.96
270_E	384_R	1.854	0.96
69_S	168_K	1.851	0.96
246_S	249_K	1.840	0.96
429_S	488_I	1.829	0.95
186_Y	190_M	1.819	0.95
207_G	222_L	1.803	0.95
247_P	250_D	1.794	0.95
246_S	250_D	1.793	0.95
459_L	786_K	1.786	0.95
428_A	434_I	1.784	0.95
41_L	48_V	1.776	0.95
804_E	807_K	1.776	0.95
434_I	439_L	1.776	0.95
579_Y	664_Y	1.768	0.95
84_Y	168_K	1.766	0.95
31_F	39_I	1.763	0.94
216_E	219_A	1.756	0.94
245_I	266_T	1.748	0.94
265_K	297_L	1.735	0.94
221_F	448_N	1.725	0.94
27_K	108_E	1.724	0.94
47_N	229_Y	1.724	0.94
465_S	480_I	1.719	0.94
417_P	449_F	1.713	0.94
537_I	544_T	1.710	0.94
27_K	104_E	1.698	0.93
323_D	327_K	1.697	0.93
249_K	253_H	1.686	0.93
676_F	697_F	1.658	0.92
579_Y	804_E	1.646	0.92
618_H	621_M	1.642	0.92
583_L	804_E	1.636	0.92
38_A	50_V	1.636	0.92
524_L	529_V	1.631	0.92
370_I	383_G	1.629	0.92
401_K	584_E	1.623	0.92
88_I	638_V	1.617	0.91
438_D	441_K	1.617	0.91
511_I	550_S	1.608	0.91
185_A	417_P	1.593	0.91
401_K	405_D	1.589	0.91
547_F	550_S	1.585	0.91
428_A	432_S	1.583	0.91
88_I	151_F	1.578	0.90
435_D	487_I	1.578	0.90
590_R	642_N	1.573	0.90
60_L	101_N	1.560	0.90
440_F	458_S	1.557	0.90
425_I	460_V	1.554	0.90
268_L	669_L	1.542	0.89
822_T	826_S	1.537	0.89
218_V	224_G	1.534	0.89
47_N	223_V	1.526	0.89
808_K	814_I	1.523	0.89
170_I	203_F	1.518	0.89
744_C	788_T	1.515	0.88
422_S	464_L	1.513	0.88
245_I	250_D	1.501	0.88
279_I	335_V	1.489	0.88
483_K	489_Y	1.487	0.88
218_V	222_L	1.478	0.87
103_L	107_N	1.473	0.87
212_V	336_V	1.471	0.87
590_R	640_S	1.464	0.87
483_K	488_I	1.460	0.87
81_D	142_H	1.460	0.87
587_K	641_D	1.459	0.86
394_V	623_I	1.455	0.86
192_E	446_S	1.448	0.86
428_A	439_L	1.440	0.86
418_L	452_L	1.438	0.86
436_R	458_S	1.427	0.85
245_I	249_K	1.424	0.85
256_E	259_V	1.424	0.85
182_K	419_D	1.413	0.85
391_D	626_Y	1.412	0.85
37_A	40_P	1.410	0.85
274_H	277_T	1.410	0.85
646_I	660_F	1.407	0.84
529_V	555_V	1.407	0.84
579_Y	801_R	1.403	0.84
269_N	273_K	1.392	0.84
198_I	201_K	1.389	0.84
240_V	249_K	1.387	0.84
265_K	269_N	1.386	0.83
630_Q	827_P	1.366	0.83
126_S	314_S	1.366	0.83
152_G	190_M	1.365	0.83
338_S	501_N	1.342	0.81
261_K	293_K	1.341	0.81
769_S	788_T	1.340	0.81
254_S	257_S	1.335	0.81
241_D	382_K	1.335	0.81
154_S	163_K	1.326	0.81
206_I	351_I	1.322	0.80
624_Y	628_L	1.321	0.80
586_G	664_Y	1.317	0.80
63_F	101_N	1.316	0.80
238_K	244_V	1.309	0.80
128_T	133_K	1.307	0.80
617_K	621_M	1.306	0.80
144_L	373_A	1.306	0.80
310_E	327_K	1.301	0.79
63_F	102_L	1.288	0.79
436_R	482_I	1.283	0.78
439_L	676_F	1.280	0.78
586_G	641_D	1.269	0.78
731_V	806_L	1.269	0.78
167_V	170_I	1.269	0.78
258_E	261_K	1.267	0.77
215_L	218_V	1.265	0.77
220_Q	447_Y	1.265	0.77
73_L	84_Y	1.263	0.77
55_G	58_K	1.253	0.77
436_R	457_Y	1.252	0.77
452_L	457_Y	1.247	0.76
244_V	249_K	1.246	0.76
845_D	848_E	1.246	0.76
847_R	852_K	1.242	0.76
532_L	547_F	1.239	0.76
159_K	162_Q	1.238	0.76
31_F	36_R	1.235	0.76
63_F	89_S	1.234	0.76
854_H	857_V	1.232	0.75
179_A	212_V	1.231	0.75
152_G	424_I	1.231	0.75
471_V	542_G	1.228	0.75
178_L	181_S	1.217	0.75
136_M	141_P	1.216	0.74
644_I	664_Y	1.210	0.74
192_E	445_R	1.205	0.74
187_L	753_R	1.202	0.74
287_T	408_I	1.200	0.73
590_R	643_L	1.200	0.73
543_R	559_E	1.198	0.73
398_V	402_L	1.196	0.73
440_F	452_L	1.196	0.73
215_L	408_I	1.195	0.73
129_T	135_K	1.195	0.73
44_Q	230_R	1.195	0.73
136_M	154_S	1.189	0.73
107_N	110_R	1.188	0.73
67_L	143_I	1.187	0.73
512_S	520_Y	1.187	0.73
675_A	723_V	1.182	0.72
418_L	460_V	1.179	0.72
403_A	406_R	1.177	0.72
102_L	105_P	1.174	0.72
579_Y	583_L	1.173	0.72
353_L	384_R	1.166	0.71
719_T	810_A	1.164	0.71
181_S	188_S	1.162	0.71
316_L	324_V	1.160	0.71
276_T	350_Y	1.156	0.71
89_S	101_N	1.156	0.71
525_E	545_Y	1.150	0.70
748_S	784_V	1.149	0.70
221_F	224_G	1.148	0.70
662_A	669_L	1.146	0.70
682_E	779_I	1.146	0.70
851_K	854_H	1.146	0.70
274_H	353_L	1.145	0.70
268_L	272_K	1.143	0.70
384_R	460_V	1.140	0.70
51_S	212_V	1.135	0.69
623_I	626_Y	1.125	0.69
512_S	523_N	1.121	0.68
40_P	44_Q	1.120	0.68
616_D	620_S	1.120	0.68
727_V	730_A	1.117	0.68
270_E	273_K	1.117	0.68
364_S	640_S	1.115	0.68
429_S	434_I	1.110	0.67
63_F	105_P	1.107	0.67
483_K	487_I	1.106	0.67
243_K	384_R	1.105	0.67
226_D	445_R	1.104	0.67
394_V	589_R	1.104	0.67
83_V	136_M	1.103	0.67
249_K	252_V	1.101	0.67
804_E	808_K	1.101	0.67
238_K	381_S	1.096	0.66
424_I	427_S	1.095	0.66
319_D	638_V	1.094	0.66
168_K	810_A	1.091	0.66
441_K	444_R	1.087	0.66
485_E	488_I	1.083	0.66
676_F	715_F	1.083	0.66
170_I	205_R	1.081	0.65
244_V	248_V	1.080	0.65
175_I	222_L	1.075	0.65
271_V	279_I	1.073	0.65
460_V	698_A	1.071	0.65
418_L	456_D	1.070	0.65
67_L	538_F	1.069	0.64
137_L	163_K	1.062	0.64
278_L	507_D	1.057	0.64
238_K	374_G	1.056	0.64
217_E	447_Y	1.056	0.64
101_N	105_P	1.055	0.63
272_K	298_A	1.054	0.63
336_V	342_L	1.053	0.63
155_I	406_R	1.051	0.63
250_D	253_H	1.046	0.63
741_F	750_M	1.046	0.63
73_L	138_K	1.041	0.62
437_D	721_D	1.039	0.62
192_E	196_N	1.038	0.62
359_S	433_P	1.033	0.62
48_V	175_I	1.031	0.62
242_I	318_R	1.028	0.61
424_I	429_S	1.022	0.61
532_L	536_D	1.021	0.61
86_I	170_I	1.016	0.60
593_A	640_S	1.014	0.60
310_E	320_V	1.010	0.60
405_D	587_K	1.008	0.60
193_L	424_I	1.007	0.60
224_G	227_R	1.004	0.60
138_K	453_S	1.003	0.59
23_W	27_K	1.002	0.59
593_A	638_V	1.002	0.59
217_E	412_H	1.001	0.59
82_K	178_L	0.998	0.59
666_R	694_D	0.998	0.59
150_S	153_I	0.997	0.59
266_T	270_E	0.996	0.59
231_I	234_A	0.995	0.59
455_S	459_L	0.990	0.58
205_R	222_L	0.990	0.58
847_R	850_L	0.988	0.58
794_E	800_L	0.986	0.58
850_L	853_L	0.986	0.58
88_I	637_K	0.985	0.58
312_H	325_E	0.981	0.58
785_M	789_I	0.981	0.58
465_S	482_I	0.978	0.58
25_R	445_R	0.978	0.58
803_K	807_K	0.977	0.57
527_E	569_S	0.977	0.57
30_T	514_V	0.977	0.57
57_G	90_P	0.977	0.57
58_K	90_P	0.977	0.57
217_E	410_S	0.976	0.57
66_I	169_W	0.974	0.57
536_D	644_I	0.973	0.57
538_F	731_V	0.970	0.57
127_D	665_G	0.966	0.57
88_I	660_F	0.963	0.56
55_G	59_T	0.962	0.56
240_V	253_H	0.962	0.56
46_Y	228_E	0.961	0.56
91_L	97_D	0.958	0.56
718_I	777_R	0.957	0.56
245_I	253_H	0.957	0.56
53_P	91_L	0.957	0.56
261_K	264_Y	0.955	0.56
433_P	489_Y	0.955	0.56
409_D	565_P	0.952	0.55
130_P	802_A	0.951	0.55
701_V	723_V	0.950	0.55
128_T	141_P	0.950	0.55
246_S	253_H	0.946	0.55
189_A	449_F	0.944	0.55
193_L	428_A	0.944	0.55
24_F	29_T	0.943	0.55
220_Q	223_V	0.943	0.55
45_N	168_K	0.941	0.55
133_K	448_N	0.940	0.54
67_L	319_D	0.940	0.54
133_K	798_D	0.936	0.54
99_Q	145_I	0.935	0.54
47_N	518_N	0.934	0.54
68_D	72_E	0.932	0.54
22_K	26_Q	0.927	0.53
483_K	486_K	0.927	0.53
497_I	752_L	0.924	0.53
462_R	466_G	0.918	0.53
86_I	218_V	0.917	0.53
259_V	285_H	0.916	0.53
49_L	208_L	0.914	0.52
285_H	538_F	0.914	0.52
70_L	119_V	0.913	0.52
294_L	337_V	0.913	0.52
165_T	445_R	0.910	0.52
420_V	504_T	0.905	0.52
408_I	519_R	0.905	0.52
67_L	385_V	0.902	0.51
240_V	246_S	0.901	0.51
662_A	805_I	0.901	0.51
843_A	850_L	0.899	0.51
46_Y	804_E	0.899	0.51
125_T	385_V	0.897	0.51
86_I	813_E	0.895	0.51
293_K	296_K	0.895	0.51
189_A	446_S	0.895	0.51
630_Q	828_F	0.894	0.51
257_S	334_K	0.894	0.51
312_H	341_S	0.892	0.51
56_S	93_A	0.890	0.50
270_E	274_H	0.890	0.50
546_E	563_Q	0.888	0.50
451_D	800_L	0.887	0.50
55_G	90_P	0.886	0.50
89_S	105_P	0.886	0.50
150_S	155_I	0.886	0.50
318_R	824_I	0.885	0.50
463_Y	666_R	0.884	0.50
167_V	203_F	0.884	0.50
249_K	618_H	0.884	0.50
423_Q	503_G	0.881	0.50
496_L	500_T	0.881	0.50
408_I	744_C	0.880	0.50
234_A	237_V	0.880	0.50
143_I	382_K	0.878	0.49
668_A	801_R	0.876	0.49
85_A	416_N	0.874	0.49
50_V	215_L	0.874	0.49
83_V	163_K	0.874	0.49
815_K	820_G	0.872	0.49
124_R	127_D	0.871	0.49
471_V	474_K	0.870	0.49
244_V	400_A	0.870	0.49
592_I	627_I	0.865	0.48
246_S	252_V	0.865	0.48
98_M	746_E	0.864	0.48
33_P	809_I	0.862	0.48
139_K	810_A	0.862	0.48
677_A	699_L	0.861	0.48
29_T	61_A	0.860	0.48
160_F	164_L	0.860	0.48
382_K	386_I	0.859	0.48
728_T	789_I	0.858	0.48
150_S	341_S	0.858	0.48
627_I	638_V	0.858	0.48
649_Y	659_I	0.857	0.48
165_T	243_K	0.857	0.48
192_E	224_G	0.857	0.48
845_D	850_L	0.856	0.48
408_I	478_A	0.854	0.48
339_S	572_S	0.854	0.48
243_K	247_P	0.853	0.47
505_I	522_G	0.852	0.47
232_V	247_P	0.852	0.47
316_L	521_V	0.850	0.47
484_E	487_I	0.849	0.47
217_E	221_F	0.849	0.47
324_V	558_K	0.847	0.47
324_V	336_V	0.846	0.47
643_L	813_E	0.845	0.47
242_I	370_I	0.843	0.47
72_E	232_V	0.842	0.47
226_D	319_D	0.842	0.47
816_V	823_N	0.841	0.47
118_D	216_E	0.840	0.46
710_N	713_S	0.840	0.46
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88_I	190_M	0.839	0.46
86_I	638_V	0.838	0.46
220_Q	404_R	0.838	0.46
514_V	554_K	0.838	0.46
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272_K	724_Y	0.837	0.46
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207_G	363_V	0.835	0.46
154_S	309_I	0.835	0.46
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73_L	165_T	0.833	0.46
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63_F	143_I	0.831	0.46
352_D	440_F	0.830	0.46
340_T	764_R	0.830	0.46
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198_I	202_E	0.827	0.45
365_R	532_L	0.827	0.45
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64_L	105_P	0.824	0.45
193_L	197_L	0.824	0.45
416_N	449_F	0.824	0.45
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754_R	759_E	0.823	0.45
255_S	258_E	0.823	0.45
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630_Q	741_F	0.821	0.45
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848_E	851_K	0.821	0.45
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480_I	488_I	0.817	0.45
191_L	222_L	0.817	0.45
187_L	428_A	0.816	0.45
267_I	271_V	0.816	0.45
846_R	849_L	0.815	0.44
848_E	853_L	0.815	0.44
463_Y	687_D	0.814	0.44
492_K	496_L	0.814	0.44
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192_E	205_R	0.809	0.44
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370_I	736_M	0.805	0.44
330_K	814_I	0.805	0.44
547_F	555_V	0.804	0.44
287_T	311_A	0.804	0.44
671_A	797_M	0.804	0.44
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180_N	364_S	0.803	0.43
54_T	210_A	0.803	0.43
138_K	168_K	0.803	0.43
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410_S	580_E	0.801	0.43
846_R	851_K	0.799	0.43
664_Y	808_K	0.797	0.43
681_S	730_A	0.796	0.43
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54_T	58_K	0.795	0.43
582_A	585_I	0.795	0.43
849_L	852_K	0.794	0.43
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503_G	694_D	0.791	0.43
148_P	313_H	0.790	0.42
438_D	719_T	0.790	0.42
267_I	346_I	0.789	0.42
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64_L	106_L	0.788	0.42
678_Y	798_D	0.787	0.42
287_T	770_E	0.785	0.42
126_S	133_K	0.784	0.42
379_S	441_K	0.784	0.42
342_L	353_L	0.784	0.42
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586_G	668_A	0.780	0.42
433_P	490_P	0.780	0.42
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402_L	584_E	0.779	0.42
453_S	492_K	0.779	0.42
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255_S	260_D	0.778	0.41
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171_I	462_R	0.776	0.41
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731_V	797_M	0.773	0.41
269_N	459_L	0.773	0.41
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171_I	628_L	0.771	0.41
269_N	272_K	0.771	0.41
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36_R	196_N	0.766	0.41
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66_I	143_I	0.764	0.40
136_M	365_R	0.763	0.40
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391_D	589_R	0.763	0.40
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620_S	624_Y	0.754	0.40
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64_L	826_S	0.752	0.39
396_C	565_P	0.752	0.39
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309_I	335_V	0.749	0.39
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145_I	624_Y	0.748	0.39
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143_I	544_T	0.742	0.39
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579_Y	805_I	0.739	0.38
219_A	223_V	0.739	0.38
419_D	791_E	0.738	0.38
747_R	787_E	0.737	0.38
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279_I	506_P	0.731	0.38
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310_E	324_V	0.724	0.37
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154_S	748_S	0.722	0.37
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555_V	748_S	0.710	0.36
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143_I	314_S	0.702	0.36
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245_I	269_N	0.697	0.35
637_K	820_G	0.697	0.35
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155_I	190_M	0.696	0.35
172_V	676_F	0.695	0.35
711_I	715_F	0.694	0.35
451_D	642_N	0.694	0.35
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432_S	638_V	0.672	0.33
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627_I	804_E	0.668	0.33
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532_L	672_L	0.666	0.33
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583_L	641_D	0.660	0.33
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318_R	326_E	0.637	0.31
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395_E	538_F	0.626	0.30
319_D	428_A	0.626	0.30
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551_K	585_I	0.621	0.30
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526_E	647_E	0.615	0.30
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313_H	347_D	0.596	0.28
443_L	457_Y	0.595	0.28
273_K	628_L	0.595	0.28
51_S	136_M	0.595	0.28
95_N	154_S	0.595	0.28
436_R	440_F	0.594	0.28
462_R	483_K	0.594	0.28
853_L	856_R	0.594	0.28
849_L	853_L	0.593	0.28
190_M	194_F	0.592	0.28
70_L	85_A	0.592	0.28
644_I	801_R	0.592	0.28
138_K	150_S	0.591	0.28
816_V	821_P	0.591	0.28
847_R	856_R	0.590	0.28
657_N	698_A	0.590	0.28
156_T	502_S	0.590	0.28
294_L	335_V	0.589	0.28
190_M	502_S	0.589	0.28
421_L	452_L	0.588	0.28
539_V	567_V	0.588	0.28
680_V	701_V	0.588	0.28
400_A	404_R	0.587	0.28
218_V	411_I	0.587	0.28
438_D	820_G	0.587	0.28
746_E	765_R	0.586	0.28
407_K	778_E	0.586	0.28
97_D	184_G	0.586	0.28
332_I	646_I	0.586	0.28
309_I	776_I	0.586	0.28
736_M	789_I	0.586	0.28
679_V	718_I	0.585	0.28
581_S	780_G	0.585	0.28
715_F	808_K	0.584	0.27
87_Y	97_D	0.584	0.27
792_I	796_H	0.584	0.27
80_E	158_P	0.583	0.27
335_V	676_F	0.582	0.27
121_V	457_Y	0.582	0.27
339_S	545_Y	0.581	0.27
433_P	645_L	0.581	0.27
64_L	537_I	0.581	0.27
242_I	400_A	0.580	0.27
103_L	807_K	0.580	0.27
133_K	170_I	0.580	0.27
327_K	808_K	0.579	0.27
278_L	440_F	0.578	0.27
85_A	102_L	0.578	0.27
248_V	251_L	0.577	0.27
316_L	537_I	0.576	0.27
591_E	813_E	0.576	0.27
147_T	371_G	0.575	0.27
184_G	284_R	0.575	0.27
518_N	723_V	0.575	0.27
848_E	852_K	0.574	0.27
154_S	828_F	0.574	0.27
175_I	696_G	0.573	0.27
186_Y	338_S	0.573	0.27
696_G	832_I	0.571	0.27
180_N	699_L	0.571	0.27
61_A	77_N	0.571	0.27
240_V	385_V	0.571	0.27
348_I	528_F	0.570	0.27
239_P	815_K	0.570	0.27
240_V	690_V	0.570	0.27
288_E	505_I	0.569	0.27
184_G	288_E	0.568	0.26
20_V	24_F	0.567	0.26
244_V	373_A	0.567	0.26
365_R	395_E	0.566	0.26
718_I	806_L	0.566	0.26
133_K	814_I	0.566	0.26
39_I	56_S	0.565	0.26
239_P	243_K	0.565	0.26
699_L	803_K	0.565	0.26
248_V	253_H	0.564	0.26
358_S	638_V	0.564	0.26
207_G	284_R	0.564	0.26
216_E	554_K	0.563	0.26
44_Q	807_K	0.562	0.26
249_K	646_I	0.562	0.26
436_R	488_I	0.562	0.26
621_M	769_S	0.561	0.26
152_G	186_Y	0.561	0.26
767_L	788_T	0.561	0.26
282_N	342_L	0.560	0.26
54_T	369_R	0.559	0.26
325_E	341_S	0.559	0.26
579_Y	808_K	0.559	0.26
67_L	798_D	0.559	0.26
278_L	388_V	0.558	0.26
72_E	76_N	0.558	0.26
594_E	813_E	0.557	0.26
28_Y	780_G	0.557	0.26
413_I	547_F	0.557	0.26
328_L	661_H	0.556	0.26
508_E	743_H	0.556	0.26
283_T	316_L	0.555	0.26
471_V	669_L	0.555	0.26
51_S	764_R	0.555	0.26
174_E	372_R	0.555	0.26
120_R	269_N	0.555	0.26
129_T	712_K	0.555	0.26
97_D	149_E	0.554	0.26
89_S	102_L	0.554	0.26
450_S	800_L	0.554	0.26
237_V	809_I	0.554	0.26
71_F	118_D	0.554	0.26
149_E	344_L	0.553	0.26
240_V	248_V	0.553	0.26
181_S	510_M	0.553	0.26
50_V	289_R	0.553	0.26
89_S	695_N	0.552	0.25
129_T	256_E	0.552	0.25
593_A	643_L	0.551	0.25
422_S	529_V	0.551	0.25
288_E	313_H	0.551	0.25
183_R	325_E	0.550	0.25
170_I	363_V	0.549	0.25
723_V	806_L	0.549	0.25
229_Y	585_I	0.548	0.25
430_L	498_F	0.548	0.25
23_W	28_Y	0.548	0.25
572_S	695_N	0.547	0.25
646_I	658_Y	0.547	0.25
453_S	781_N	0.547	0.25
23_W	64_L	0.547	0.25
240_V	243_K	0.547	0.25
402_L	407_K	0.546	0.25
642_N	781_N	0.546	0.25
241_D	660_F	0.545	0.25
506_P	527_E	0.545	0.25
71_F	217_E	0.545	0.25
367_L	403_A	0.545	0.25
176_H	368_Q	0.545	0.25
531_I	735_E	0.545	0.25
506_P	746_E	0.545	0.25
309_I	760_T	0.544	0.25
845_D	851_K	0.544	0.25
740_R	829_S	0.544	0.25
572_S	749_F	0.543	0.25
191_L	551_K	0.543	0.25
839_D	847_R	0.543	0.25
594_E	597_K	0.542	0.25
373_A	772_L	0.541	0.25
60_L	70_L	0.541	0.25
89_S	276_T	0.541	0.25
355_I	646_I	0.541	0.25
590_R	808_K	0.540	0.25
193_L	442_I	0.540	0.25
278_L	821_P	0.540	0.25
142_H	207_G	0.540	0.25
220_Q	816_V	0.539	0.25
437_D	441_K	0.539	0.25
93_A	349_G	0.539	0.25
651_D	740_R	0.538	0.25
176_H	358_S	0.538	0.25
269_N	435_D	0.538	0.25
173_D	372_R	0.538	0.25
165_T	781_N	0.538	0.25
100_R	326_E	0.536	0.25
246_S	251_L	0.536	0.25
88_I	529_V	0.536	0.25
165_T	644_I	0.536	0.25
242_I	245_I	0.536	0.25
52_S	94_L	0.536	0.25
373_A	553_S	0.535	0.24
297_L	824_I	0.535	0.24
480_I	638_V	0.535	0.24
461_L	482_I	0.534	0.24
648_I	816_V	0.533	0.24
242_I	249_K	0.532	0.24
696_G	829_S	0.532	0.24
156_T	208_L	0.532	0.24
110_R	117_P	0.531	0.24
642_N	808_K	0.531	0.24
243_K	267_I	0.531	0.24
413_I	447_Y	0.530	0.24
781_N	804_E	0.530	0.24
435_D	486_K	0.530	0.24
256_E	847_R	0.529	0.24
48_V	735_E	0.529	0.24
145_I	262_G	0.529	0.24
783_P	826_S	0.528	0.24
585_I	680_V	0.528	0.24
229_Y	235_R	0.528	0.24
33_P	67_L	0.528	0.24
365_R	739_R	0.527	0.24
585_I	802_A	0.527	0.24
248_V	622_S	0.527	0.24
679_V	726_I	0.527	0.24
65_G	204_V	0.526	0.24
736_M	796_H	0.526	0.24
107_N	637_K	0.526	0.24
504_T	694_D	0.525	0.24
528_F	693_T	0.525	0.24
166_D	332_I	0.525	0.24
32_T	295_R	0.525	0.24
139_K	441_K	0.524	0.24
673_S	750_M	0.524	0.24
274_H	492_K	0.524	0.24
435_D	440_F	0.524	0.24
226_D	232_V	0.524	0.24
347_D	371_G	0.524	0.24
257_S	644_I	0.523	0.24
195_R	445_R	0.523	0.24
158_P	455_S	0.523	0.24
152_G	785_M	0.523	0.24
514_V	556_I	0.523	0.24
56_S	378_R	0.523	0.24
149_E	183_R	0.523	0.24
43_K	135_K	0.522	0.24
804_E	811_S	0.522	0.24
357_L	814_I	0.522	0.24
289_R	714_L	0.522	0.24
409_D	545_Y	0.522	0.24
55_G	211_T	0.521	0.24
337_V	364_S	0.521	0.24
319_D	458_S	0.521	0.24
320_V	410_S	0.521	0.24
394_V	856_R	0.521	0.24
770_E	776_I	0.521	0.24
504_T	742_R	0.520	0.24
720_P	799_I	0.520	0.24
23_W	423_Q	0.519	0.24
235_R	238_K	0.519	0.24
168_K	686_T	0.519	0.24
524_L	533_S	0.519	0.24
109_L	261_K	0.518	0.23
570_W	787_E	0.518	0.23
662_A	693_T	0.518	0.23
35_Q	90_P	0.518	0.23
171_I	330_K	0.518	0.23
235_R	357_L	0.517	0.23
53_P	772_L	0.517	0.23
125_T	240_V	0.516	0.23
44_Q	811_S	0.515	0.23
367_L	408_I	0.514	0.23
576_P	667_R	0.514	0.23
277_T	355_I	0.514	0.23
805_I	809_I	0.513	0.23
95_N	358_S	0.513	0.23
803_K	811_S	0.513	0.23
87_Y	119_V	0.512	0.23
120_R	628_L	0.512	0.23
408_I	847_R	0.511	0.23
212_V	215_L	0.511	0.23
37_A	134_Q	0.511	0.23
239_P	297_L	0.511	0.23
444_R	593_A	0.511	0.23
232_V	239_P	0.510	0.23
334_K	422_S	0.510	0.23
274_H	785_M	0.510	0.23
162_Q	591_E	0.509	0.23
60_L	503_G	0.509	0.23
731_V	810_A	0.509	0.23
264_Y	290_V	0.509	0.23
31_F	281_T	0.509	0.23
89_S	106_L	0.509	0.23
389_D	392_D	0.508	0.23
183_R	288_E	0.508	0.23
312_H	557_V	0.508	0.23
219_A	229_Y	0.508	0.23
63_F	100_R	0.508	0.23
587_K	811_S	0.508	0.23
50_V	474_K	0.507	0.23
721_D	781_N	0.507	0.23
54_T	59_T	0.507	0.23
52_S	339_S	0.507	0.23
444_R	560_A	0.507	0.23
442_I	806_L	0.506	0.23
171_I	178_L	0.506	0.23
33_P	704_D	0.505	0.23
287_T	291_A	0.505	0.23
365_R	792_I	0.505	0.23
840_V	843_A	0.504	0.23
51_S	231_I	0.504	0.23
165_T	330_K	0.504	0.23
838_S	852_K	0.504	0.23
528_F	538_F	0.504	0.23
89_S	186_Y	0.503	0.23
44_Q	815_K	0.503	0.23
241_D	267_I	0.502	0.23
694_D	742_R	0.502	0.23
259_V	281_T	0.502	0.23
469_F	650_D	0.502	0.23
183_R	522_G	0.501	0.22
441_K	454_E	0.501	0.22
122_G	389_D	0.501	0.22
172_V	175_I	0.501	0.22
284_R	347_D	0.501	0.22
39_I	68_D	0.501	0.22
101_N	503_G	0.501	0.22
826_S	833_I	0.500	0.22
318_R	457_Y	0.500	0.22
537_I	798_D	0.500	0.22

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2va8A	1	0.7177	100	0.738	Contact Map
2p6rA	1	0.7017	100	0.739	Contact Map
2zj8A	2	0.712	100	0.741	Contact Map
4f92B	1	0.8217	100	0.749	Contact Map
4pxaA	1	0.4469	100	0.753	Contact Map
4d25A	1	0.4389	100	0.753	Contact Map
4w7sA	2	0.4697	100	0.754	Contact Map
4nhoA	1	0.4389	100	0.754	Contact Map
5agaA	4	0.7817	100	0.755	Contact Map
2db3A	1	0.4354	100	0.755	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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