TREZ - SULSO - GREMLIN Contacts

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TREZ - Malto-oligosyltrehalose trehalohydrolase

UniProt:	P95867	Sequences: MTFGYKLDEDGVTFNLWAPYQRKVKLKILNRGIYEMERDDKGYFTITLDNVRVGDRYKYILDDNSEVPDPASRYQPEGVHGYSEIISPDFEWDDENSVKVKREDLVIYELHIGTFTSEGTFEGVIKKLNYLKELGVTAIEIMPIAQFPGKKDWGYDGVYLYAVQNSYGGPSGFRKLVNEAHKLGLAVILDVVYNHVGPEGNYMVKLGPYFSEKYKTPWGLTFNFDDAGSDEVRKFILENVEYWINEFHVDGFRLDAVHAIIDNSPKHILEDIADVVHKYDKIVIAESDLNDPRVVNPKEKCGYNIDAQWVDDFHHAIHAFLTGERQGYYSDFGSIGDIVKSYKDVFIYDGKYSNFRRKTHGKSVGDLDGCKFVVYIQNHDQVGNRGGGERLIKLVDKESYKIAAALYILSPYIPMIFMGEEYGEENPFYYFSDFSDPKLIQGVREGRRRENGQETDPQSDCTFNDSKLSWKINDDILSFYKSLIKIRKEYGLACNRKLSVENGNYWLTVKGNGCLAVYVFSKSVIEMKYSGTLVLSSNSSFPSQITESKYELDKGFALYKL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	561 (472)
Sequences:	10758 (7037)
Seq/√Len:	323.9

ECOLI - GLGX GLGB MALZ YGAQ TREC AMY1 SUCP AMY2
BACSU - PULA BBMA GLGB O16G3 O16G1 O16G2 TREC AMY
SULSO - TREZ Q7LX99

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
129_N	183_L	4.590	1.00
122_E	175_K	4.439	1.00
179_E	182_K	4.176	1.00
122_E	172_G	3.725	1.00
133_E	481_K	3.642	1.00
233_R	271_D	3.374	1.00
116_T	127_K	3.340	1.00
174_R	246_E	3.102	1.00
132_K	183_L	3.070	1.00
139_I	180_A	3.016	1.00
404_A	480_Y	2.960	1.00
409_L	509_V	2.947	1.00
169_G	172_G	2.933	1.00
179_E	183_L	2.893	1.00
36_M	46_I	2.794	1.00
485_K	489_E	2.747	1.00
423_G	476_I	2.727	1.00
181_H	250_D	2.644	1.00
173_F	177_V	2.559	1.00
377_Q	420_E	2.512	1.00
128_L	183_L	2.498	1.00
277_H	306_D	2.446	1.00
234_K	238_E	2.321	1.00
122_E	125_I	2.293	1.00
92_W	248_H	2.277	1.00
242_Y	247_F	2.191	1.00
175_K	179_E	2.170	1.00
125_I	175_K	2.155	1.00
196_V	210_F	2.106	1.00
124_V	176_L	2.095	1.00
104_D	494_C	2.088	1.00
141_I	144_I	2.087	1.00
173_F	249_V	2.069	1.00
244_I	281_K	2.068	1.00
478_S	481_K	2.051	1.00
501_E	504_N	2.049	1.00
408_I	484_I	2.043	1.00
171_S	174_R	2.026	1.00
510_K	513_G	2.025	1.00
180_A	185_L	2.023	1.00
409_L	516_A	2.012	1.00
125_I	179_E	2.009	1.00
241_E	275_V	1.992	1.00
98_V	101_K	1.984	1.00
97_S	101_K	1.984	1.00
106_V	484_I	1.982	1.00
180_A	187_V	1.979	1.00
105_L	138_A	1.948	1.00
275_V	278_K	1.906	1.00
193_Y	239_N	1.905	1.00
209_Y	212_E	1.897	1.00
273_A	277_H	1.890	1.00
52_R	55_D	1.879	1.00
146_Q	162_A	1.859	1.00
141_I	176_L	1.856	1.00
405_A	479_F	1.855	1.00
131_L	136_V	1.834	1.00
490_Y	512_N	1.831	1.00
23_K	35_E	1.819	1.00
482_S	485_K	1.816	1.00
110_L	115_F	1.816	1.00
23_K	62_D	1.798	1.00
90_F	178_N	1.781	1.00
25_K	60_I	1.780	1.00
94_D	248_H	1.780	1.00
12_V	85_I	1.769	1.00
133_E	477_L	1.763	1.00
11_G	47_T	1.756	1.00
441_Q	445_E	1.736	1.00
401_K	479_F	1.723	1.00
490_Y	514_C	1.722	1.00
172_G	175_K	1.720	1.00
508_T	517_V	1.710	1.00
510_K	515_L	1.698	1.00
161_Y	239_N	1.678	1.00
34_Y	46_I	1.662	1.00
478_S	482_S	1.654	1.00
124_V	141_I	1.636	1.00
176_L	180_A	1.631	1.00
33_I	60_I	1.618	1.00
178_N	182_K	1.616	1.00
12_V	51_V	1.607	1.00
15_N	45_T	1.597	1.00
112_I	124_V	1.595	1.00
24_V	61_L	1.593	1.00
241_E	245_N	1.589	1.00
240_V	272_I	1.572	1.00
76_P	80_H	1.571	1.00
173_F	176_L	1.564	1.00
146_Q	165_N	1.563	1.00
14_F	59_Y	1.561	1.00
126_K	179_E	1.542	1.00
93_D	178_N	1.539	1.00
392_I	395_V	1.531	1.00
161_Y	238_E	1.527	1.00
477_L	481_K	1.519	1.00
217_P	222_F	1.519	1.00
131_L	185_L	1.515	1.00
144_I	173_F	1.513	1.00
474_D	478_S	1.511	1.00
122_E	126_K	1.507	1.00
60_I	66_E	1.504	1.00
25_K	62_D	1.493	1.00
131_L	139_I	1.486	1.00
25_K	35_E	1.485	1.00
56_R	76_P	1.485	1.00
242_Y	246_E	1.478	1.00
51_V	55_D	1.454	1.00
105_L	282_I	1.447	1.00
90_F	93_D	1.436	1.00
226_D	229_S	1.431	1.00
130_Y	477_L	1.425	1.00
163_V	173_F	1.424	1.00
276_V	281_K	1.419	1.00
110_L	124_V	1.416	1.00
72_S	83_S	1.413	1.00
56_R	84_E	1.412	1.00
505_Y	521_S	1.409	1.00
95_E	248_H	1.406	1.00
268_I	272_I	1.405	1.00
25_K	33_I	1.403	1.00
215_K	222_F	1.398	1.00
218_W	221_T	1.390	1.00
22_R	62_D	1.389	1.00
492_L	514_C	1.388	1.00
422_Y	443_V	1.385	1.00
22_R	64_N	1.384	1.00
245_N	279_Y	1.374	1.00
215_K	218_W	1.366	1.00
16_L	61_L	1.359	1.00
402_I	518_Y	1.358	1.00
401_K	476_I	1.345	1.00
188_I	284_I	1.344	1.00
16_L	24_V	1.339	1.00
207_G	212_E	1.333	1.00
110_L	131_L	1.325	1.00
13_T	47_T	1.316	1.00
218_W	224_F	1.306	1.00
275_V	279_Y	1.305	1.00
13_T	45_T	1.283	1.00
241_E	279_Y	1.278	1.00
393_K	425_E	1.274	1.00
138_A	186_A	1.269	1.00
74_Y	86_I	1.264	1.00
231_E	234_K	1.263	1.00
271_D	275_V	1.262	1.00
230_D	234_K	1.258	1.00
191_V	240_V	1.257	1.00
321_L	403_A	1.250	1.00
90_F	175_K	1.249	1.00
340_K	343_K	1.248	1.00
128_L	180_A	1.244	1.00
219_G	222_F	1.232	1.00
110_L	139_I	1.226	1.00
220_L	223_N	1.226	1.00
105_L	137_T	1.223	1.00
15_N	43_Y	1.216	1.00
68_P	75_Q	1.213	1.00
138_A	188_I	1.209	1.00
237_L	275_V	1.207	1.00
31_R	60_I	1.203	1.00
120_T	123_G	1.197	1.00
27_K	60_I	1.193	1.00
90_F	248_H	1.192	1.00
217_P	221_T	1.191	1.00
34_Y	48_L	1.189	1.00
75_Q	159_Y	1.186	1.00
402_I	520_F	1.182	1.00
218_W	222_F	1.179	1.00
129_N	133_E	1.179	1.00
128_L	179_E	1.175	1.00
429_Y	441_Q	1.175	1.00
188_I	251_G	1.166	1.00
267_H	270_E	1.163	1.00
173_F	189_L	1.160	1.00
441_Q	444_R	1.156	1.00
509_V	516_A	1.153	1.00
127_K	130_Y	1.152	1.00
112_I	141_I	1.149	1.00
272_I	283_V	1.145	1.00
404_A	416_I	1.144	1.00
145_A	239_N	1.143	1.00
532_T	535_L	1.141	1.00
27_K	33_I	1.141	1.00
209_Y	213_K	1.138	1.00
121_F	163_V	1.136	1.00
72_S	75_Q	1.135	1.00
204_V	208_P	1.134	1.00
244_I	276_V	1.134	1.00
404_A	483_L	1.129	1.00
146_Q	164_Q	1.126	1.00
416_I	480_Y	1.121	1.00
339_V	342_Y	1.115	1.00
93_D	182_K	1.109	1.00
131_L	135_G	1.109	1.00
214_Y	217_P	1.106	1.00
375_Y	378_N	1.106	1.00
274_D	298_K	1.103	1.00
481_K	485_K	1.102	1.00
447_R	451_N	1.096	1.00
313_F	410_S	1.094	1.00
215_K	220_L	1.085	1.00
271_D	274_D	1.084	1.00
116_T	126_K	1.078	1.00
401_K	475_D	1.078	1.00
74_Y	84_E	1.075	1.00
210_F	213_K	1.073	1.00
533_L	536_S	1.071	1.00
137_T	488_K	1.071	1.00
113_G	117_S	1.066	1.00
416_I	420_E	1.066	1.00
134_L	477_L	1.064	1.00
438_K	441_Q	1.061	1.00
107_I	374_V	1.053	1.00
276_V	279_Y	1.052	1.00
339_V	343_K	1.051	1.00
317_I	403_A	1.049	1.00
145_A	157_G	1.048	1.00
400_Y	423_G	1.047	1.00
220_L	224_F	1.043	1.00
207_G	210_F	1.040	1.00
115_F	124_V	1.038	1.00
113_G	167_Y	1.036	1.00
418_M	443_V	1.036	1.00
121_F	172_G	1.036	1.00
444_R	447_R	1.035	1.00
234_K	275_V	1.033	1.00
161_Y	242_Y	1.033	1.00
270_E	274_D	1.031	1.00
237_L	272_I	1.030	1.00
154_G	167_Y	1.029	1.00
217_P	220_L	1.028	1.00
338_I	344_D	1.027	1.00
273_A	283_V	1.022	1.00
404_A	420_E	1.021	1.00
51_V	85_I	1.020	1.00
189_L	249_V	1.019	1.00
219_G	224_F	1.019	1.00
295_V	298_K	1.017	1.00
26_L	46_I	1.015	1.00
332_F	335_I	1.013	1.00
161_Y	235_F	1.003	1.00
198_P	214_Y	1.002	1.00
527_M	530_S	1.002	1.00
296_N	299_E	1.001	1.00
319_A	322_T	1.001	1.00
173_F	247_F	1.000	1.00
406_L	518_Y	0.999	1.00
163_V	243_W	0.999	1.00
217_P	224_F	0.996	1.00
12_V	52_R	0.992	1.00
338_I	342_Y	0.990	1.00
215_K	224_F	0.987	1.00
204_V	207_G	0.985	1.00
240_V	254_L	0.983	1.00
376_I	403_A	0.982	1.00
442_G	446_G	0.978	1.00
342_Y	345_V	0.974	1.00
132_K	185_L	0.973	1.00
215_K	223_N	0.973	1.00
338_I	341_S	0.973	1.00
107_I	188_I	0.972	1.00
528_K	532_T	0.970	1.00
484_I	488_K	0.970	1.00
440_I	443_V	0.966	1.00
237_L	241_E	0.965	1.00
126_K	129_N	0.965	1.00
28_I	34_Y	0.964	1.00
474_D	477_L	0.956	1.00
341_S	344_D	0.954	1.00
215_K	221_T	0.953	1.00
309_W	314_H	0.952	1.00
214_Y	219_G	0.951	1.00
107_I	138_A	0.950	1.00
324_E	327_G	0.949	1.00
67_V	70_P	0.942	1.00
106_V	408_I	0.941	1.00
175_K	178_N	0.940	1.00
448_R	477_L	0.937	1.00
319_A	395_V	0.937	1.00
55_D	85_I	0.937	1.00
408_I	416_I	0.936	1.00
528_K	531_G	0.934	1.00
239_N	242_Y	0.934	1.00
339_V	344_D	0.932	1.00
78_G	150_K	0.916	1.00
293_R	296_N	0.914	1.00
218_W	223_N	0.914	1.00
119_G	123_G	0.912	1.00
69_D	72_S	0.910	1.00
106_V	488_K	0.910	1.00
170_P	247_F	0.908	1.00
274_D	278_K	0.904	1.00
140_E	309_W	0.902	1.00
486_I	490_Y	0.902	1.00
393_K	396_D	0.900	1.00
445_E	449_R	0.898	1.00
129_N	132_K	0.898	1.00
237_L	271_D	0.897	1.00
221_T	224_F	0.894	1.00
269_L	272_I	0.893	1.00
391_L	395_V	0.892	1.00
160_L	235_F	0.892	1.00
58_K	66_E	0.892	1.00
39_D	45_T	0.888	1.00
340_K	344_D	0.886	1.00
342_Y	346_F	0.885	1.00
267_H	271_D	0.885	1.00
75_Q	162_A	0.882	1.00
102_R	282_I	0.882	1.00
270_E	304_N	0.874	1.00
240_V	252_F	0.872	1.00
208_P	211_S	0.871	1.00
144_I	189_L	0.869	1.00
336_G	339_V	0.864	1.00
315_H	319_A	0.864	1.00
121_F	168_G	0.863	1.00
112_I	121_F	0.861	1.00
311_D	314_H	0.860	1.00
163_V	242_Y	0.859	1.00
177_V	187_V	0.858	1.00
219_G	223_N	0.858	1.00
216_T	220_L	0.855	1.00
446_G	449_R	0.854	1.00
171_S	175_K	0.850	1.00
125_I	176_L	0.850	1.00
37_E	45_T	0.849	1.00
114_T	152_D	0.844	1.00
317_I	406_L	0.844	1.00
208_P	213_K	0.838	1.00
193_Y	236_I	0.837	1.00
68_P	72_S	0.836	1.00
157_G	160_L	0.835	1.00
517_V	527_M	0.833	1.00
255_D	286_E	0.832	1.00
405_A	483_L	0.831	1.00
422_Y	477_L	0.830	1.00
28_I	31_R	0.830	1.00
53_V	87_S	0.828	1.00
479_F	483_L	0.826	1.00
492_L	512_N	0.825	1.00
67_V	71_A	0.824	1.00
448_R	451_N	0.823	1.00
136_V	185_L	0.821	1.00
90_F	94_D	0.820	1.00
233_R	267_H	0.818	1.00
137_T	185_L	0.817	1.00
404_A	476_I	0.815	1.00
293_R	297_P	0.813	1.00
100_V	138_A	0.813	1.00
110_L	418_M	0.812	1.00
292_P	295_V	0.812	1.00
134_L	484_I	0.812	1.00
17_W	231_E	0.810	1.00
214_Y	222_F	0.809	1.00
399_S	402_I	0.805	1.00
28_I	55_D	0.804	1.00
216_T	221_T	0.804	1.00
318_H	322_T	0.803	1.00
89_D	171_S	0.803	1.00
115_F	130_Y	0.803	1.00
400_Y	476_I	0.802	1.00
530_S	536_S	0.800	1.00
272_I	276_V	0.800	1.00
294_V	297_P	0.799	1.00
66_E	69_D	0.798	1.00
240_V	276_V	0.798	1.00
97_S	100_V	0.797	1.00
493_A	514_C	0.797	1.00
118_E	123_G	0.797	1.00
68_P	71_A	0.797	1.00
48_L	51_V	0.796	1.00
125_I	172_G	0.795	1.00
205_K	208_P	0.795	1.00
477_L	480_Y	0.794	1.00
266_K	270_E	0.792	1.00
119_G	127_K	0.791	1.00
337_D	340_K	0.790	1.00
209_Y	235_F	0.789	1.00
124_V	180_A	0.788	1.00
170_P	246_E	0.781	1.00
370_C	400_Y	0.781	1.00
180_A	183_L	0.777	1.00
66_E	70_P	0.775	1.00
195_H	255_D	0.775	1.00
145_A	249_V	0.772	1.00
499_S	510_K	0.771	1.00
19_P	42_G	0.771	1.00
104_D	495_N	0.771	1.00
145_A	189_L	0.767	1.00
162_A	170_P	0.765	1.00
377_Q	403_A	0.765	1.00
27_K	58_K	0.764	1.00
508_T	511_G	0.761	0.99
309_W	313_F	0.760	0.99
276_V	283_V	0.760	0.99
409_L	518_Y	0.760	0.99
313_F	317_I	0.759	0.99
405_A	409_L	0.751	0.99
527_M	532_T	0.751	0.99
497_K	500_V	0.748	0.99
215_K	219_G	0.745	0.99
100_V	184_G	0.744	0.99
241_E	276_V	0.744	0.99
528_K	533_L	0.743	0.99
106_V	136_V	0.742	0.99
126_K	175_K	0.739	0.99
195_H	379_H	0.738	0.99
297_P	346_F	0.738	0.99
346_F	369_G	0.736	0.99
91_E	94_D	0.733	0.99
122_E	169_G	0.732	0.99
214_Y	218_W	0.732	0.99
40_D	45_T	0.732	0.99
302_G	305_I	0.731	0.99
507_L	511_G	0.731	0.99
216_T	222_F	0.730	0.99
303_Y	306_D	0.729	0.99
130_Y	133_E	0.728	0.99
284_I	415_M	0.721	0.99
132_K	184_G	0.721	0.99
208_P	212_E	0.720	0.99
68_P	83_S	0.719	0.99
74_Y	77_E	0.719	0.99
406_L	520_F	0.718	0.99
18_A	21_Q	0.717	0.99
216_T	223_N	0.717	0.99
92_W	95_E	0.714	0.99
286_E	379_H	0.711	0.99
310_V	314_H	0.710	0.99
88_P	92_W	0.709	0.99
505_Y	511_G	0.708	0.99
476_I	479_F	0.708	0.99
491_G	495_N	0.707	0.99
521_S	525_I	0.706	0.99
159_Y	162_A	0.706	0.99
378_N	392_I	0.706	0.99
532_T	536_S	0.706	0.99
302_G	306_D	0.703	0.99
440_I	444_R	0.703	0.99
14_F	85_I	0.703	0.99
444_R	448_R	0.703	0.99
343_K	346_F	0.703	0.99
444_R	449_R	0.702	0.99
66_E	71_A	0.702	0.99
527_M	531_G	0.699	0.99
53_V	89_D	0.699	0.99
255_D	380_D	0.695	0.99
109_E	142_M	0.693	0.99
253_R	286_E	0.692	0.99
282_I	307_A	0.692	0.99
339_V	346_F	0.691	0.99
405_A	518_Y	0.690	0.99
146_Q	158_V	0.688	0.99
373_V	414_P	0.688	0.99
389_E	399_S	0.687	0.99
525_I	528_K	0.686	0.99
338_I	343_K	0.685	0.99
27_K	34_Y	0.685	0.99
121_F	144_I	0.684	0.99
22_R	63_D	0.684	0.99
36_M	59_Y	0.684	0.99
323_G	327_G	0.683	0.99
22_R	65_S	0.683	0.99
400_Y	404_A	0.681	0.99
70_P	74_Y	0.679	0.99
23_K	60_I	0.678	0.99
129_N	179_E	0.677	0.99
319_A	324_E	0.674	0.99
341_S	345_V	0.674	0.99
508_T	515_L	0.671	0.99
217_P	223_N	0.670	0.99
443_V	448_R	0.670	0.99
204_V	210_F	0.670	0.99
177_V	249_V	0.669	0.99
339_V	345_V	0.669	0.99
531_G	536_S	0.668	0.99
67_V	72_S	0.668	0.99
71_A	74_Y	0.668	0.99
90_F	174_R	0.665	0.99
393_K	397_K	0.664	0.99
207_G	211_S	0.664	0.99
319_A	323_G	0.663	0.99
73_R	242_Y	0.663	0.99
138_A	185_L	0.662	0.99
37_E	46_I	0.661	0.99
227_A	236_I	0.660	0.99
108_Y	421_E	0.660	0.99
205_K	210_F	0.660	0.99
104_D	488_K	0.659	0.99
69_D	74_Y	0.657	0.99
430_Y	441_Q	0.657	0.99
269_L	276_V	0.655	0.98
531_G	535_L	0.655	0.98
529_Y	532_T	0.654	0.98
107_I	373_V	0.654	0.98
244_I	252_F	0.654	0.98
320_F	520_F	0.653	0.98
409_L	486_I	0.653	0.98
138_A	282_I	0.653	0.98
340_K	346_F	0.653	0.98
261_I	266_K	0.653	0.98
528_K	536_S	0.651	0.98
27_K	31_R	0.651	0.98
178_N	248_H	0.650	0.98
216_T	219_G	0.650	0.98
53_V	86_I	0.649	0.98
414_P	487_R	0.649	0.98
76_P	84_E	0.647	0.98
156_D	197_G	0.647	0.98
235_F	239_N	0.647	0.98
244_I	279_Y	0.646	0.98
111_H	142_M	0.646	0.98
338_I	346_F	0.645	0.98
337_D	343_K	0.645	0.98
150_K	164_Q	0.645	0.98
530_S	535_L	0.644	0.98
207_G	213_K	0.644	0.98
73_R	246_E	0.644	0.98
58_K	82_Y	0.643	0.98
216_T	224_F	0.642	0.98
398_E	401_K	0.642	0.98
54_G	84_E	0.642	0.98
230_D	233_R	0.642	0.98
119_G	122_E	0.641	0.98
530_S	533_L	0.640	0.98
88_P	91_E	0.639	0.98
214_Y	221_T	0.638	0.98
124_V	139_I	0.634	0.98
121_F	173_F	0.633	0.98
309_W	415_M	0.632	0.98
147_F	157_G	0.630	0.98
174_R	247_F	0.629	0.98
35_E	38_R	0.629	0.98
394_L	524_V	0.628	0.98
135_G	485_K	0.627	0.98
253_R	379_H	0.627	0.98
71_A	209_Y	0.625	0.98
116_T	119_G	0.624	0.98
130_Y	422_Y	0.624	0.98
155_Y	286_E	0.624	0.98
118_E	442_G	0.623	0.98
292_P	297_P	0.623	0.98
337_D	344_D	0.622	0.98
195_H	253_R	0.621	0.98
193_Y	254_L	0.621	0.98
94_D	178_N	0.621	0.98
70_P	73_R	0.621	0.98
233_R	237_L	0.620	0.98
506_W	511_G	0.619	0.98
445_E	448_R	0.619	0.98
76_P	82_Y	0.619	0.98
255_D	379_H	0.618	0.98
100_V	104_D	0.615	0.98
439_L	442_G	0.615	0.98
314_H	318_H	0.615	0.98
442_G	445_E	0.615	0.98
338_I	345_V	0.614	0.98
403_A	406_L	0.614	0.98
107_I	415_M	0.614	0.98
425_E	441_Q	0.613	0.98
62_D	65_S	0.610	0.98
409_L	483_L	0.610	0.98
274_D	299_E	0.609	0.98
397_K	451_N	0.608	0.98
506_W	527_M	0.608	0.98
75_Q	83_S	0.608	0.98
14_F	26_L	0.607	0.98
206_L	209_Y	0.607	0.98
444_R	450_E	0.607	0.98
235_F	238_E	0.606	0.97
91_E	95_E	0.603	0.97
133_E	478_S	0.602	0.97
93_D	248_H	0.601	0.97
108_Y	134_L	0.601	0.97
151_K	430_Y	0.601	0.97
505_Y	520_F	0.600	0.97
321_L	520_F	0.600	0.97
181_H	187_V	0.598	0.97
429_Y	440_I	0.597	0.97
447_R	450_E	0.596	0.97
132_K	488_K	0.596	0.97
56_R	82_Y	0.595	0.97
214_Y	220_L	0.593	0.97
406_L	410_S	0.591	0.97
341_S	346_F	0.591	0.97
125_I	129_N	0.591	0.97
89_D	92_W	0.588	0.97
387_G	396_D	0.585	0.97
258_H	288_D	0.584	0.97
164_Q	167_Y	0.584	0.97
310_V	374_V	0.584	0.97
475_D	478_S	0.583	0.97
430_Y	438_K	0.581	0.97
427_P	439_L	0.578	0.97
446_G	450_E	0.578	0.97
115_F	131_L	0.577	0.97
340_K	345_V	0.575	0.97
337_D	346_F	0.574	0.97
26_L	48_L	0.573	0.97
123_G	176_L	0.572	0.96
121_F	176_L	0.572	0.96
443_V	450_E	0.572	0.96
178_N	181_H	0.572	0.96
146_Q	166_S	0.571	0.96
529_Y	536_S	0.571	0.96
16_L	21_Q	0.571	0.96
426_N	444_R	0.571	0.96
439_L	445_E	0.569	0.96
527_M	535_L	0.569	0.96
141_I	173_F	0.569	0.96
501_E	506_W	0.569	0.96
118_E	126_K	0.569	0.96
94_D	182_K	0.568	0.96
155_Y	255_D	0.568	0.96
95_E	178_N	0.567	0.96
385_R	400_Y	0.567	0.96
123_G	126_K	0.567	0.96
96_N	99_K	0.566	0.96
136_V	421_E	0.566	0.96
293_R	298_K	0.565	0.96
88_P	171_S	0.564	0.96
236_I	268_I	0.562	0.96
174_R	242_Y	0.558	0.96
491_G	494_C	0.557	0.96
254_L	283_V	0.556	0.96
370_C	374_V	0.555	0.96
313_F	316_A	0.555	0.96
195_H	286_E	0.554	0.96
163_V	170_P	0.553	0.96
26_L	59_Y	0.553	0.96
295_V	299_E	0.552	0.96
409_L	493_A	0.550	0.96
438_K	443_V	0.549	0.96
125_I	183_L	0.549	0.96
97_S	102_R	0.548	0.96
319_A	341_S	0.547	0.95
500_V	510_K	0.547	0.95
67_V	74_Y	0.547	0.95
443_V	447_R	0.546	0.95
18_A	42_G	0.546	0.95
266_K	304_N	0.544	0.95
71_A	238_E	0.543	0.95
269_L	273_A	0.543	0.95
174_R	178_N	0.543	0.95
102_R	105_L	0.543	0.95
294_V	298_K	0.539	0.95
192_V	286_E	0.537	0.95
10_D	13_T	0.537	0.95
319_A	325_R	0.537	0.95
476_I	480_Y	0.536	0.95
321_L	406_L	0.535	0.95
388_G	391_L	0.534	0.95
192_V	195_H	0.534	0.95
100_V	103_E	0.534	0.95
507_L	510_K	0.533	0.95
253_R	380_D	0.533	0.95
39_D	43_Y	0.533	0.95
501_E	505_Y	0.532	0.95
29_L	58_K	0.531	0.95
105_L	188_I	0.530	0.95
112_I	144_I	0.527	0.94
479_F	482_S	0.527	0.94
223_N	227_A	0.527	0.94
335_I	338_I	0.527	0.94
48_L	52_R	0.526	0.94
32_G	60_I	0.524	0.94
382_V	428_F	0.524	0.94
515_L	531_G	0.523	0.94
193_Y	240_V	0.523	0.94
66_E	77_E	0.522	0.94
190_D	255_D	0.521	0.94
238_E	241_E	0.521	0.94
485_K	488_K	0.521	0.94
200_G	203_M	0.521	0.94
14_F	48_L	0.520	0.94
274_D	277_H	0.520	0.94
206_L	210_F	0.520	0.94
273_A	276_V	0.519	0.94
170_P	242_Y	0.518	0.94
160_L	224_F	0.518	0.94
188_I	282_I	0.517	0.94
206_L	212_E	0.515	0.94
420_E	480_Y	0.513	0.94
288_D	314_H	0.513	0.94
147_F	167_Y	0.513	0.94
496_R	499_S	0.513	0.94
396_D	399_S	0.512	0.94
445_E	451_N	0.512	0.94
131_L	180_A	0.512	0.94
490_Y	494_C	0.511	0.94
268_I	275_V	0.511	0.94
481_K	484_I	0.510	0.93
107_I	413_I	0.509	0.93
135_G	484_I	0.508	0.93
257_V	269_L	0.507	0.93
47_T	50_N	0.507	0.93
158_V	197_G	0.507	0.93
336_G	340_K	0.506	0.93
256_A	259_A	0.506	0.93
186_A	282_I	0.506	0.93
136_V	416_I	0.505	0.93
506_W	525_I	0.505	0.93
219_G	259_A	0.504	0.93
192_V	255_D	0.501	0.93
323_G	341_S	0.501	0.93
35_E	44_F	0.501	0.93
272_I	275_V	0.500	0.93

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3vgfA	2	0.9804	100	0.244	Contact Map
2bhuA	1	0.9519	100	0.279	Contact Map
3wdhA	1	0.8913	100	0.282	Contact Map
1bf2A	1	0.9162	100	0.288	Contact Map
3m07A	1	0.9626	100	0.292	Contact Map
2wanA	1	0.9055	100	0.292	Contact Map
2e8yA	1	0.9127	100	0.293	Contact Map
2vr5A	5	0.9109	100	0.298	Contact Map
1ea9C	2	0.8681	100	0.304	Contact Map
1wzlA	2	0.8663	100	0.305	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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