GREMLIN Database
DPS - DNA protection during starvation protein
UniProt: P95855 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 188 (145)
Sequences: 1286 (676)
Seq/√Len: 56.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
76_L151_R3.8171.00
114_K118_K3.5261.00
137_M140_G3.0481.00
118_K122_E2.7881.00
25_K28_D2.7161.00
51_L116_I2.5991.00
23_I140_G2.4491.00
128_I132_K2.4101.00
108_E122_E2.2821.00
112_D115_E2.1151.00
25_K140_G2.0531.00
177_R182_N1.9881.00
69_E72_L1.9741.00
128_I160_E1.8490.99
49_M75_E1.8100.99
61_E65_D1.7910.99
78_T90_R1.7590.99
147_D150_Q1.7270.99
114_K178_S1.7120.99
35_A39_T1.7010.99
114_K167_L1.6960.99
29_K137_M1.6790.99
108_E126_C1.6440.99
31_V86_G1.6370.99
56_G179_S1.6270.99
37_E156_E1.5620.98
41_Y71_R1.5410.98
68_L71_R1.5270.98
53_G85_G1.5080.98
114_K182_N1.4900.98
168_Y179_S1.4710.97
52_T79_Q1.4630.97
81_I86_G1.4250.97
96_A109_N1.4070.96
33_A131_W1.4050.96
26_L140_G1.3840.96
121_L164_L1.3680.96
128_I156_E1.3450.95
161_A165_E1.3350.95
70_D159_H1.2970.94
139_Y146_Y1.2910.94
134_V149_A1.2680.94
36_A130_T1.2630.94
29_K133_E1.2580.93
25_K137_M1.2290.93
34_T81_I1.2220.92
40_T70_D1.2150.92
77_M148_L1.2140.92
127_A156_E1.2110.92
156_E159_H1.1950.92
37_E73_H1.1940.92
32_K130_T1.1900.91
62_I65_D1.1890.91
69_E155_E1.1830.91
77_M145_T1.1660.91
144_R154_Q1.1440.90
45_T48_R1.1430.90
126_C130_T1.1400.90
135_C149_A1.1280.89
29_K134_V1.1140.88
135_C150_Q1.0750.87
26_L138_T1.0730.86
129_R133_E1.0690.86
114_K183_A1.0620.86
47_L120_L1.0560.86
66_A70_D1.0560.86
35_A94_Q1.0480.85
114_K177_R1.0480.85
43_Y120_L1.0450.85
180_P184_P1.0310.84
53_G83_E1.0300.84
95_L108_E1.0180.83
121_L125_Q1.0160.83
70_D73_H1.0150.83
66_A73_H1.0090.83
29_K130_T1.0080.83
139_Y143_P1.0080.83
73_H159_H0.9990.82
51_L60_K0.9950.82
61_E162_W0.9930.82
52_T64_E0.9930.82
112_D182_N0.9910.82
50_H116_I0.9820.81
33_A130_T0.9750.81
64_E68_L0.9620.80
73_H124_E0.9610.80
52_T60_K0.9590.80
24_K28_D0.9500.79
40_T73_H0.9490.79
50_H110_W0.9440.79
69_E156_E0.9390.78
125_Q160_E0.9360.78
110_W120_L0.9350.78
76_L152_I0.9280.77
35_A116_I0.9260.77
73_H156_E0.9210.77
67_R71_R0.9070.76
169_G180_P0.9050.76
45_T64_E0.8990.75
154_Q157_I0.8960.75
48_R60_K0.8830.74
35_A92_I0.8680.72
62_I162_W0.8650.72
77_M152_I0.8560.71
44_Y124_E0.8550.71
37_E124_E0.8420.70
165_E168_Y0.8380.70
60_K64_E0.8350.69
48_R64_E0.8310.69
92_I95_L0.8280.69
45_T67_R0.8220.68
70_D124_E0.8170.68
50_H82_Y0.8120.67
26_L137_M0.8100.67
39_T94_Q0.8080.67
40_T66_A0.8050.67
68_L72_L0.8020.66
69_E73_H0.7850.65
73_H155_E0.7840.65
45_T82_Y0.7800.64
64_E67_R0.7790.64
143_P146_Y0.7770.64
75_E79_Q0.7760.64
80_R145_T0.7710.63
23_I137_M0.7710.63
80_R142_D0.7680.63
133_E137_M0.7670.63
162_W166_L0.7650.63
108_E119_V0.7630.62
37_E159_H0.7550.62
127_A155_E0.7550.62
46_I87_G0.7490.61
63_A69_E0.7470.61
32_K133_E0.7450.61
37_E127_A0.7400.60
89_P94_Q0.7400.60
126_C156_E0.7380.60
132_K143_P0.7360.60
138_T149_A0.7260.59
50_H54_M0.7200.58
133_E141_K0.7180.58
118_K167_L0.7000.56
65_D69_E0.6960.55
135_C146_Y0.6940.55
77_M149_A0.6900.55
73_H127_A0.6830.54
40_T43_Y0.6790.54
37_E74_F0.6740.53
40_T123_A0.6680.52
119_V122_E0.6630.52
62_I66_A0.6620.52
34_T77_M0.6600.52
51_L113_P0.6590.51
136_D141_K0.6590.51
70_D127_A0.6570.51
32_K35_A0.6560.51
36_A131_W0.6560.51
59_L113_P0.6530.51
41_Y67_R0.6510.51
39_T93_R0.6480.50
120_L163_F0.6460.50
36_A127_A0.6460.50
87_G111_K0.6430.50
29_K140_G0.6400.49
68_L75_E0.6400.49
150_Q154_Q0.6390.49
45_T75_E0.6390.49
131_W156_E0.6350.49
83_E156_E0.6340.49
33_A127_A0.6320.49
37_E44_Y0.6310.48
24_K141_K0.6290.48
113_P182_N0.6200.47
110_W115_E0.6200.47
45_T71_R0.6190.47
71_R93_R0.6180.47
125_Q128_I0.6180.47
56_G113_P0.6150.47
128_I152_I0.6120.46
93_R96_A0.6120.46
115_E157_I0.6110.46
33_A77_M0.6090.46
31_V81_I0.6050.46
90_R96_A0.6040.45
135_C153_L0.6000.45
121_L160_E0.5990.45
46_I109_N0.5900.44
92_I180_P0.5870.44
89_P111_K0.5870.44
57_E61_E0.5820.43
127_A131_W0.5770.43
67_R91_D0.5750.42
36_A66_A0.5710.42
27_V81_I0.5600.41
28_D137_M0.5590.41
36_A152_I0.5580.41
70_D113_P0.5580.41
51_L63_A0.5550.40
95_L119_V0.5520.40
32_K94_Q0.5490.40
91_D111_K0.5490.40
144_R148_L0.5470.39
117_L163_F0.5430.39
135_C139_Y0.5400.39
65_D72_L0.5350.38
57_E150_Q0.5340.38
144_R150_Q0.5310.38
31_V34_T0.5230.37
66_A127_A0.5210.37
50_H109_N0.5150.36
123_A131_W0.5110.36
124_E127_A0.5090.36
28_D32_K0.5080.35
42_Y161_A0.5070.35
157_I161_A0.5060.35
147_D153_L0.5060.35
168_Y178_S0.5050.35
72_L155_E0.5000.35
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2clbA 6 0.8989 100 0.481 Contact Map
2v8tA 5 0.9096 100 0.525 Contact Map
2c2uA 6 0.9096 100 0.527 Contact Map
3ak8A 6 0.8138 100 0.534 Contact Map
2c2jA 6 0.867 100 0.536 Contact Map
1o9iA 6 0.8989 100 0.537 Contact Map
4cybA 6 0.8936 100 0.539 Contact Map
2xgwA 6 0.8085 100 0.542 Contact Map
4m32A 6 0.8511 100 0.543 Contact Map
1tjoA 6 0.9309 100 0.543 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0067 seconds.