SAHH - SULSO - GREMLIN Contacts

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SAHH - Adenosylhomocysteinase

UniProt:	P50252	Sequences: MSYKIKDLSLASEGKKQIEWAERHMPTLMEIRKRFKAEKPLKGINISAVLHVTKETAALVKTLKIGGANVALAGSNPLSTQDDVAAALVEEGISVFAWKGENETEYYSNIESIVKIHEPNIVMDDGADLHAYIHEKVSSKLDIYGGTEETTTGVIRLKAMEKDGVLKYPLVAVNNAYTKYLFDNRYGTGQSAIDGILRATNILIAGKIAVVAGYGWVGRGIANRLRGMGARVIVTEVDPIRALEAVMDGFDVMPIAEASKVGDIFVTATGNTKAIRVEHMLNMKDGAILSNAGHFNVEVDVKGLKETAVKVRNIRPYVDEYTLPNGKRVYLLADGRLVNLAAAEGHPSEVMDMSFANQALAVEYLVKNRGKLEKKVYNMPMELDYEVARIKLKSMGIQIDELTEEQKEYLEQWKSGT	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	417 (412)
Sequences:	1874 (664)
Seq/√Len:	32.7

HALSA - SAHH
SULSO - SAHH

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
34_R	386_E	4.630	1.00
301_V	331_L	4.413	1.00
212_A	255_I	4.012	1.00
300_D	303_G	3.830	1.00
221_I	268_A	3.492	1.00
209_A	225_L	3.383	1.00
231_R	251_D	3.279	1.00
47_S	113_I	3.276	1.00
262_G	265_F	3.220	1.00
39_K	42_K	3.192	1.00
18_I	57_A	3.147	1.00
263_D	284_K	3.141	1.00
161_E	375_K	3.047	1.00
134_H	167_K	3.021	1.00
260_K	282_N	2.964	1.00
265_F	275_I	2.940	1.00
333_A	342_A	2.780	1.00
34_R	38_E	2.625	1.00
210_V	262_G	2.606	1.00
368_N	371_K	2.603	1.00
160_M	165_V	2.547	1.00
233_I	253_M	2.544	1.00
404_E	408_E	2.524	1.00
363_E	367_K	2.505	1.00
305_K	311_V	2.495	1.00
111_E	136_K	2.384	0.99
313_N	319_D	2.376	0.99
311_V	321_Y	2.371	0.99
290_S	338_V	2.364	0.99
36_K	65_I	2.329	0.99
210_V	235_T	2.322	0.99
257_E	398_Q	2.319	0.99
361_A	379_M	2.317	0.99
272_T	405_E	2.313	0.99
115_K	137_V	2.302	0.99
214_Y	248_D	2.298	0.99
265_F	287_A	2.272	0.99
277_V	281_L	2.258	0.99
102_N	105_E	2.226	0.99
5_I	8_L	2.201	0.99
235_T	400_D	2.195	0.99
45_N	69_N	2.187	0.99
255_I	258_A	2.187	0.99
44_I	120_N	2.154	0.99
44_I	366_V	2.146	0.99
34_R	363_E	2.103	0.98
312_R	320_E	2.102	0.98
273_K	405_E	2.082	0.98
121_I	362_V	2.034	0.98
259_S	265_F	2.025	0.98
281_L	325_N	2.000	0.98
265_F	283_M	1.991	0.98
108_S	112_S	1.990	0.98
194_D	198_R	1.910	0.97
320_E	328_R	1.881	0.97
364_Y	372_L	1.870	0.97
379_M	383_L	1.866	0.97
273_K	300_D	1.847	0.96
276_R	279_H	1.846	0.96
78_L	334_D	1.822	0.96
146_G	170_L	1.788	0.96
110_I	132_Y	1.765	0.95
5_I	89_V	1.742	0.95
17_Q	83_D	1.725	0.95
4_K	108_S	1.713	0.94
193_I	225_L	1.708	0.94
73_A	113_I	1.706	0.94
141_L	167_K	1.705	0.94
111_E	137_V	1.688	0.94
31_I	356_A	1.638	0.93
35_F	66_G	1.637	0.93
146_G	168_Y	1.618	0.93
15_K	61_K	1.616	0.92
35_F	65_I	1.614	0.92
212_A	235_T	1.613	0.92
21_A	58_A	1.601	0.92
138_S	167_K	1.592	0.92
196_I	338_V	1.573	0.91
262_G	287_A	1.563	0.91
176_A	379_M	1.549	0.91
133_I	143_I	1.539	0.90
3_Y	8_L	1.535	0.90
66_G	359_A	1.520	0.90
193_I	228_M	1.519	0.90
373_E	377_Y	1.519	0.90
333_A	338_V	1.516	0.90
256_A	278_E	1.510	0.90
310_K	322_T	1.496	0.89
135_E	138_S	1.496	0.89
407_K	411_E	1.485	0.89
45_N	120_N	1.483	0.89
33_K	37_A	1.471	0.88
285_D	328_R	1.459	0.88
39_K	65_I	1.450	0.88
193_I	204_I	1.446	0.87
22_E	61_K	1.442	0.87
255_I	259_S	1.440	0.87
98_W	109_N	1.439	0.87
112_S	115_K	1.436	0.87
305_K	321_Y	1.424	0.87
277_V	303_G	1.421	0.87
214_Y	250_F	1.413	0.86
202_I	288_I	1.410	0.86
323_L	327_K	1.407	0.86
254_P	257_E	1.390	0.85
289_L	329_V	1.387	0.85
111_E	132_Y	1.384	0.85
204_I	228_M	1.379	0.85
238_D	241_R	1.377	0.85
233_I	261_V	1.375	0.85
259_S	262_G	1.373	0.85
208_I	231_R	1.372	0.85
276_R	300_D	1.368	0.84
193_I	209_A	1.362	0.84
257_E	260_K	1.360	0.84
195_G	199_A	1.350	0.84
4_K	98_W	1.346	0.83
185_R	248_D	1.341	0.83
64_K	93_I	1.341	0.83
66_G	363_E	1.331	0.83
13_E	17_Q	1.330	0.83
130_H	170_L	1.318	0.82
235_T	255_I	1.317	0.82
277_V	306_E	1.297	0.81
223_N	248_D	1.296	0.81
320_E	330_Y	1.286	0.80
208_I	233_I	1.281	0.80
121_I	147_T	1.278	0.80
178_T	357_N	1.277	0.80
381_M	385_Y	1.271	0.80
156_R	159_A	1.255	0.79
210_V	255_I	1.250	0.78
38_E	367_K	1.247	0.78
48_A	72_L	1.247	0.78
280_M	329_V	1.245	0.78
192_A	292_A	1.244	0.78
204_I	230_A	1.244	0.78
398_Q	401_E	1.238	0.78
389_R	401_E	1.227	0.77
23_R	285_D	1.226	0.77
111_E	115_K	1.225	0.77
254_P	258_A	1.211	0.76
35_F	359_A	1.210	0.76
280_M	289_L	1.209	0.76
4_K	109_N	1.209	0.76
303_G	307_T	1.195	0.75
144_Y	369_R	1.192	0.75
199_A	342_A	1.187	0.75
22_E	32_R	1.186	0.75
13_E	83_D	1.178	0.74
271_N	410_L	1.178	0.74
273_K	276_R	1.176	0.74
266_V	338_V	1.175	0.74
30_E	33_K	1.174	0.74
17_Q	54_K	1.169	0.74
73_A	110_I	1.169	0.74
253_M	258_A	1.160	0.73
41_L	362_V	1.157	0.73
302_K	331_L	1.155	0.73
281_L	323_L	1.152	0.72
49_V	110_I	1.146	0.72
361_A	383_L	1.146	0.72
41_L	66_G	1.145	0.72
404_E	414_K	1.144	0.72
190_Q	194_D	1.141	0.72
202_I	207_K	1.138	0.72
256_A	282_N	1.137	0.71
30_E	393_K	1.123	0.71
177_Y	240_I	1.123	0.71
266_V	290_S	1.122	0.70
121_I	365_L	1.118	0.70
386_E	389_R	1.113	0.70
99_K	317_Y	1.110	0.70
272_T	297_V	1.102	0.69
46_I	63_L	1.089	0.68
86_A	89_V	1.087	0.68
208_I	251_D	1.085	0.68
255_I	265_F	1.076	0.67
275_I	283_M	1.076	0.67
401_E	407_K	1.073	0.67
404_E	407_K	1.068	0.67
12_S	90_E	1.068	0.67
312_R	322_T	1.060	0.66
374_K	377_Y	1.059	0.66
357_N	387_V	1.058	0.66
190_Q	197_L	1.045	0.65
108_S	111_E	1.044	0.65
120_N	123_M	1.044	0.65
254_P	398_Q	1.040	0.65
127_A	170_L	1.039	0.64
8_L	89_V	1.039	0.64
255_I	279_H	1.035	0.64
98_W	102_N	1.031	0.64
256_A	279_H	1.031	0.64
286_G	320_E	1.029	0.64
171_V	361_A	1.028	0.64
6_K	98_W	1.025	0.63
61_K	91_E	1.023	0.63
204_I	264_I	1.020	0.63
122_V	168_Y	1.020	0.63
4_K	112_S	1.014	0.63
209_A	266_V	1.009	0.62
24_H	349_E	1.008	0.62
277_V	307_T	1.005	0.62
185_R	244_E	1.001	0.61
73_A	129_L	0.996	0.61
301_V	305_K	0.994	0.61
107_Y	416_G	0.987	0.60
106_Y	128_D	0.983	0.60
55_E	348_S	0.979	0.60
211_V	221_I	0.978	0.60
15_K	91_E	0.977	0.60
321_Y	331_L	0.976	0.60
262_G	275_I	0.967	0.59
71_A	96_F	0.963	0.58
15_K	90_E	0.961	0.58
197_L	228_M	0.960	0.58
255_I	262_G	0.955	0.58
176_A	361_A	0.955	0.58
85_A	95_V	0.955	0.58
60_V	72_L	0.951	0.58
177_Y	180_Y	0.950	0.57
137_V	141_L	0.942	0.57
408_E	414_K	0.940	0.57
251_D	261_V	0.938	0.56
32_R	62_T	0.933	0.56
275_I	280_M	0.933	0.56
122_V	133_I	0.928	0.56
13_E	316_P	0.928	0.56
144_Y	365_L	0.926	0.55
152_T	337_L	0.921	0.55
151_T	174_N	0.919	0.55
113_I	129_L	0.918	0.55
211_V	225_L	0.912	0.54
393_K	398_Q	0.908	0.54
223_N	226_R	0.908	0.54
98_W	108_S	0.906	0.54
154_V	171_V	0.902	0.53
198_R	344_E	0.900	0.53
58_A	61_K	0.900	0.53
209_A	264_I	0.893	0.53
311_V	319_D	0.889	0.52
123_M	147_T	0.889	0.52
216_W	244_E	0.887	0.52
18_I	87_A	0.886	0.52
106_Y	354_S	0.885	0.52
178_T	243_L	0.881	0.52
32_R	65_I	0.880	0.52
188_T	292_A	0.878	0.52
47_S	117_H	0.878	0.52
98_W	105_E	0.876	0.51
123_M	154_V	0.875	0.51
207_K	264_I	0.874	0.51
210_V	265_F	0.873	0.51
246_V	397_I	0.871	0.51
210_V	233_I	0.869	0.51
147_T	366_V	0.869	0.51
311_V	334_D	0.868	0.51
70_V	93_I	0.867	0.51
49_V	73_A	0.865	0.50
130_H	146_G	0.863	0.50
17_Q	55_E	0.862	0.50
96_F	117_H	0.860	0.50
301_V	321_Y	0.860	0.50
255_I	275_I	0.859	0.50
385_Y	389_R	0.858	0.50
5_I	9_S	0.857	0.50
350_V	357_N	0.841	0.48
161_E	374_K	0.835	0.48
71_A	117_H	0.834	0.48
44_I	121_I	0.831	0.48
148_E	153_G	0.830	0.48
141_L	168_Y	0.829	0.47
22_E	29_M	0.828	0.47
8_L	90_E	0.822	0.47
364_Y	368_N	0.822	0.47
309_V	323_L	0.817	0.46
52_V	60_V	0.814	0.46
48_A	60_V	0.811	0.46
352_D	391_K	0.808	0.46
281_L	327_K	0.807	0.46
254_P	400_D	0.804	0.45
402_L	410_L	0.802	0.45
177_Y	238_D	0.800	0.45
23_R	286_G	0.798	0.45
52_V	72_L	0.798	0.45
133_I	140_K	0.794	0.45
300_D	306_E	0.794	0.45
18_I	58_A	0.793	0.44
190_Q	224_R	0.786	0.44
276_R	281_L	0.785	0.44
221_I	292_A	0.780	0.43
277_V	280_M	0.780	0.43
262_G	283_M	0.778	0.43
28_L	59_L	0.776	0.43
54_K	83_D	0.775	0.43
30_E	390_I	0.772	0.43
40_P	66_G	0.770	0.43
195_G	198_R	0.769	0.43
7_D	10_L	0.768	0.42
54_K	344_E	0.767	0.42
101_E	109_N	0.763	0.42
171_V	237_V	0.758	0.42
53_T	348_S	0.757	0.42
89_V	96_F	0.755	0.41
60_V	88_L	0.755	0.41
208_I	261_V	0.754	0.41
34_R	389_R	0.754	0.41
351_M	358_Q	0.754	0.41
246_V	395_M	0.754	0.41
351_M	355_F	0.753	0.41
144_Y	366_V	0.751	0.41
403_T	410_L	0.751	0.41
87_A	91_E	0.750	0.41
135_E	160_M	0.750	0.41
278_E	281_L	0.749	0.41
31_I	359_A	0.747	0.41
359_A	363_E	0.746	0.41
37_A	142_D	0.746	0.41
128_D	294_H	0.745	0.41
253_M	398_Q	0.742	0.40
364_Y	367_K	0.741	0.40
76_N	128_D	0.739	0.40
325_N	328_R	0.738	0.40
248_D	333_A	0.735	0.40
46_I	366_V	0.735	0.40
115_K	139_S	0.734	0.40
149_E	351_M	0.733	0.40
171_V	255_I	0.733	0.40
221_I	224_R	0.732	0.40
392_L	397_I	0.731	0.39
22_E	58_A	0.731	0.39
303_G	331_L	0.728	0.39
237_V	400_D	0.726	0.39
51_H	294_H	0.726	0.39
309_V	327_K	0.725	0.39
52_V	55_E	0.725	0.39
318_V	332_L	0.725	0.39
279_H	283_M	0.723	0.39
54_K	315_R	0.722	0.39
391_K	395_M	0.720	0.39
137_V	140_K	0.719	0.39
233_I	258_A	0.718	0.38
127_A	146_G	0.718	0.38
158_K	389_R	0.717	0.38
134_H	141_L	0.715	0.38
171_V	364_Y	0.713	0.38
55_E	343_A	0.711	0.38
296_N	301_V	0.709	0.38
55_E	344_E	0.709	0.38
337_L	346_H	0.706	0.38
152_T	294_H	0.705	0.37
5_I	256_A	0.705	0.37
154_V	376_V	0.705	0.37
15_K	32_R	0.702	0.37
53_T	344_E	0.701	0.37
11_A	90_E	0.700	0.37
38_E	363_E	0.699	0.37
401_E	415_S	0.699	0.37
114_V	137_V	0.697	0.37
162_K	408_E	0.696	0.37
193_I	197_L	0.696	0.37
212_A	274_A	0.696	0.37
51_H	79_S	0.695	0.37
32_R	61_K	0.693	0.37
258_A	262_G	0.693	0.37
212_A	273_K	0.692	0.36
254_P	401_E	0.692	0.36
48_A	53_T	0.691	0.36
280_M	283_M	0.691	0.36
345_G	351_M	0.686	0.36
45_N	117_H	0.685	0.36
197_L	286_G	0.684	0.36
5_I	168_Y	0.683	0.36
263_D	286_G	0.681	0.36
142_D	373_E	0.679	0.35
393_K	411_E	0.678	0.35
322_T	328_R	0.675	0.35
281_L	306_E	0.674	0.35
302_K	305_K	0.673	0.35
185_R	223_N	0.673	0.35
115_K	140_K	0.672	0.35
103_E	129_L	0.671	0.35
217_V	268_A	0.670	0.35
190_Q	205_A	0.670	0.35
172_A	376_V	0.665	0.34
128_D	149_E	0.663	0.34
408_E	412_Q	0.662	0.34
219_R	296_N	0.662	0.34
53_T	349_E	0.657	0.34
32_R	36_K	0.657	0.34
294_H	337_L	0.655	0.34
336_R	340_L	0.655	0.34
233_I	251_D	0.653	0.33
34_R	403_T	0.652	0.33
276_R	368_N	0.647	0.33
16_K	312_R	0.643	0.33
176_A	387_V	0.643	0.33
121_I	366_V	0.643	0.33
29_M	58_A	0.642	0.33
193_I	224_R	0.642	0.33
197_L	290_S	0.641	0.33
307_T	323_L	0.641	0.33
313_N	334_D	0.640	0.33
134_H	168_Y	0.639	0.32
42_K	118_E	0.638	0.32
346_H	355_F	0.637	0.32
176_A	216_W	0.635	0.32
38_E	66_G	0.635	0.32
51_H	337_L	0.634	0.32
196_I	290_S	0.634	0.32
51_H	76_N	0.633	0.32
264_I	329_V	0.631	0.32
209_A	221_I	0.629	0.32
254_P	260_K	0.629	0.32
76_N	80_T	0.628	0.32
27_T	352_D	0.628	0.32
345_G	355_F	0.628	0.32
257_E	282_N	0.627	0.32
324_P	327_K	0.627	0.32
13_E	16_K	0.627	0.32
281_L	324_P	0.627	0.32
346_H	351_M	0.626	0.32
274_A	329_V	0.625	0.31
3_Y	90_E	0.625	0.31
288_I	379_M	0.625	0.31
59_L	359_A	0.625	0.31
140_K	143_I	0.624	0.31
32_R	162_K	0.623	0.31
180_Y	216_W	0.621	0.31
200_T	267_T	0.621	0.31
69_N	325_N	0.621	0.31
154_V	318_V	0.620	0.31
353_M	356_A	0.619	0.31
97_A	350_V	0.618	0.31
190_Q	228_M	0.617	0.31
302_K	306_E	0.616	0.31
121_I	143_I	0.615	0.31
114_V	133_I	0.613	0.31
99_K	318_V	0.612	0.31
128_D	156_R	0.611	0.30
219_R	268_A	0.610	0.30
34_R	360_L	0.609	0.30
64_K	91_E	0.609	0.30
205_A	338_V	0.609	0.30
105_E	349_E	0.609	0.30
210_V	259_S	0.607	0.30
21_A	52_V	0.605	0.30
12_S	16_K	0.604	0.30
337_L	340_L	0.604	0.30
48_A	75_S	0.603	0.30
267_T	291_N	0.602	0.30
9_S	162_K	0.602	0.30
29_M	33_K	0.601	0.30
106_Y	295_F	0.600	0.30
143_I	365_L	0.600	0.30
176_A	190_Q	0.600	0.30
407_K	412_Q	0.600	0.30
142_D	381_M	0.600	0.30
29_M	32_R	0.599	0.30
110_I	129_L	0.598	0.30
31_I	363_E	0.598	0.30
158_K	175_N	0.597	0.29
212_A	258_A	0.596	0.29
190_Q	338_V	0.596	0.29
241_R	263_D	0.595	0.29
199_A	333_A	0.595	0.29
130_H	217_V	0.594	0.29
160_M	167_K	0.592	0.29
27_T	391_K	0.592	0.29
58_A	62_T	0.592	0.29
55_E	350_V	0.592	0.29
196_I	332_L	0.591	0.29
401_E	414_K	0.589	0.29
26_P	239_P	0.587	0.29
379_M	387_V	0.587	0.29
52_V	199_A	0.586	0.29
220_G	294_H	0.585	0.29
177_Y	381_M	0.585	0.29
4_K	96_F	0.582	0.28
149_E	358_Q	0.582	0.28
214_Y	223_N	0.582	0.28
210_V	253_M	0.582	0.28
65_I	91_E	0.582	0.28
407_K	410_L	0.580	0.28
307_T	324_P	0.580	0.28
109_N	112_S	0.579	0.28
9_S	408_E	0.577	0.28
294_H	340_L	0.576	0.28
60_V	123_M	0.575	0.28
161_E	377_Y	0.574	0.28
133_I	141_L	0.574	0.28
64_K	70_V	0.573	0.28
365_L	383_L	0.572	0.28
131_A	167_K	0.571	0.28
243_L	391_K	0.570	0.28
149_E	354_S	0.570	0.28
34_R	368_N	0.570	0.28
21_A	348_S	0.570	0.28
277_V	300_D	0.569	0.28
147_T	154_V	0.569	0.28
161_E	214_Y	0.569	0.28
11_A	89_V	0.568	0.28
256_A	276_R	0.567	0.27
6_K	375_K	0.567	0.27
143_I	168_Y	0.566	0.27
104_T	108_S	0.566	0.27
280_M	307_T	0.565	0.27
286_G	328_R	0.565	0.27
28_L	62_T	0.564	0.27
47_S	111_E	0.564	0.27
97_A	154_V	0.564	0.27
74_G	349_E	0.562	0.27
290_S	342_A	0.561	0.27
53_T	357_N	0.561	0.27
129_L	140_K	0.560	0.27
291_N	294_H	0.560	0.27
6_K	102_N	0.559	0.27
122_V	129_L	0.559	0.27
185_R	216_W	0.558	0.27
364_Y	380_P	0.557	0.27
172_A	342_A	0.556	0.27
132_Y	138_S	0.556	0.27
176_A	378_N	0.556	0.27
38_E	65_I	0.556	0.27
301_V	360_L	0.555	0.27
125_D	183_D	0.554	0.27
76_N	294_H	0.554	0.27
386_E	390_I	0.554	0.27
49_V	131_A	0.554	0.27
202_I	264_I	0.553	0.27
58_A	178_T	0.552	0.26
144_Y	257_E	0.552	0.26
136_K	140_K	0.552	0.26
128_D	354_S	0.552	0.26
152_T	346_H	0.550	0.26
259_S	297_V	0.550	0.26
63_L	354_S	0.550	0.26
151_T	346_H	0.547	0.26
79_S	157_L	0.546	0.26
50_L	123_M	0.546	0.26
312_R	328_R	0.544	0.26
151_T	345_G	0.544	0.26
147_T	362_V	0.543	0.26
278_E	303_G	0.543	0.26
281_L	307_T	0.542	0.26
7_D	11_A	0.541	0.26
360_L	386_E	0.540	0.26
8_L	11_A	0.540	0.26
192_A	221_I	0.540	0.26
162_K	411_E	0.540	0.26
159_A	163_D	0.538	0.26
277_V	324_P	0.538	0.26
199_A	318_V	0.538	0.26
374_K	386_E	0.537	0.26
289_L	408_E	0.536	0.25
258_A	261_V	0.536	0.25
354_S	362_V	0.535	0.25
212_A	282_N	0.535	0.25
221_I	266_V	0.535	0.25
155_I	410_L	0.535	0.25
103_E	110_I	0.534	0.25
42_K	69_N	0.533	0.25
136_K	393_K	0.532	0.25
58_A	101_E	0.532	0.25
123_M	362_V	0.532	0.25
41_L	63_L	0.531	0.25
296_N	346_H	0.530	0.25
209_A	306_E	0.530	0.25
219_R	240_I	0.529	0.25
125_D	182_F	0.529	0.25
174_N	182_F	0.529	0.25
102_N	168_Y	0.528	0.25
185_R	333_A	0.528	0.25
385_Y	407_K	0.525	0.25
241_R	244_E	0.525	0.25
76_N	106_Y	0.524	0.25
104_T	211_V	0.524	0.25
226_R	307_T	0.523	0.25
97_A	182_F	0.523	0.25
274_A	297_V	0.523	0.25
361_A	381_M	0.522	0.25
340_L	345_G	0.522	0.25
114_V	140_K	0.521	0.25
102_N	132_Y	0.521	0.25
59_L	149_E	0.521	0.25
404_E	415_S	0.519	0.24
23_R	328_R	0.519	0.24
296_N	302_K	0.518	0.24
257_E	261_V	0.518	0.24
54_K	357_N	0.518	0.24
53_T	350_V	0.517	0.24
103_E	168_Y	0.514	0.24
41_L	363_E	0.513	0.24
196_I	266_V	0.513	0.24
408_E	413_W	0.513	0.24
84_V	315_R	0.513	0.24
118_E	139_S	0.512	0.24
364_Y	382_E	0.511	0.24
197_L	204_I	0.509	0.24
49_V	107_Y	0.509	0.24
163_D	282_N	0.509	0.24
209_A	230_A	0.508	0.24
274_A	410_L	0.507	0.24
211_V	266_V	0.507	0.24
151_T	187_G	0.507	0.24
393_K	396_G	0.507	0.24
25_M	128_D	0.506	0.24
46_I	115_K	0.504	0.23
163_D	413_W	0.503	0.23
42_K	90_E	0.503	0.23
103_E	131_A	0.503	0.23
393_K	404_E	0.502	0.23
58_A	99_K	0.502	0.23
382_E	389_R	0.502	0.23
62_T	65_I	0.501	0.23
51_H	291_N	0.501	0.23
104_T	142_D	0.500	0.23

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3ce6A	4	1	100	0.329	Contact Map
1v8bA	4	1	100	0.338	Contact Map
3d64A	4	0.9952	100	0.34	Contact Map
4lvcA	4	0.9952	100	0.341	Contact Map
3gvpA	4	0.9976	100	0.351	Contact Map
3h9uA	5	0.9976	100	0.375	Contact Map
3ondA	4	1	100	0.376	Contact Map
3x2fA	4	0.9736	100	0.397	Contact Map
1ygyA	4	0.7794	99.8	0.874	Contact Map
3fr7A	2	0.5851	99.8	0.875	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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