FUMC - SULSO - GREMLIN Contacts

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FUMC - Fumarate hydratase class II

UniProt:	P39461	Sequences: MKYTDTAPKLFMNTGTKFPRRIIWSMGVLKKSCAKVNADLGLLDKKIADSIIKASDDLIDGKLDDKIVLDVFQTGSGTGLNMNVNEVIAEVASSYSNLKVHPNDHVNFGQSSNDTVPTAIRIAAVAEVTNRLLPALQQIISSLNKKAEEYKDVIKAGRTHLRDALPVTLGQELSAYADAFQHEHEQVMNILEYVKELPIGGTATGTGLNSHPEFQERVINEINRITGLGFKPANRFRAMRLLTDLLLLSGALRNIAVDLYRLGQDIRLMFSGPLTGLNEIDLPTQEEIAGSSIMPGKTNPVTVEATLLISAQVVGLDHANQFASMLGEFELSMGIPLVGYNIVTQVNFISEALEKMSRLVIDGMVANVEKMKRYAESSPSLITIVSPVIGYDKATEIGKKLNKGMSIREALRELGYSDNEINKILDLSKLVKPGFTAK	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	438 (395)
Sequences:	11011 (5907)
Seq/√Len:	297.2

ECOLI - FUMC ASPA ARLY PUR8
BACSU - ASPA FUMC ARLY PUR8
HALSA - FUMC ARLY Q9HS42
SULSO - FUMC Q980P8 ARLY

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
38_A	48_A	3.823	1.00
31_K	56_D	3.456	1.00
47_I	105_H	3.345	1.00
39_D	221_E	3.268	1.00
370_K	373_R	3.236	1.00
35_K	52_I	3.215	1.00
35_K	225_I	2.910	1.00
137_Q	184_H	2.837	1.00
25_S	126_A	2.809	1.00
281_D	365_V	2.767	1.00
417_S	420_E	2.739	1.00
256_A	313_V	2.732	1.00
140_I	181_Q	2.711	1.00
133_L	188_M	2.661	1.00
372_K	376_E	2.650	1.00
128_V	248_L	2.609	1.00
142_S	362_D	2.590	1.00
130_N	191_L	2.545	1.00
21_R	347_N	2.497	1.00
193_Y	247_L	2.490	1.00
169_L	366_A	2.456	1.00
316_L	345_Q	2.454	1.00
221_E	224_R	2.436	1.00
133_L	184_H	2.382	1.00
281_D	367_N	2.372	1.00
146_K	149_E	2.301	1.00
309_I	352_A	2.243	1.00
125_V	195_K	2.238	1.00
38_A	45_K	2.231	1.00
44_D	47_I	2.201	1.00
253_R	317_D	2.198	1.00
195_K	229_G	2.110	1.00
283_P	363_G	2.096	1.00
152_D	368_V	2.091	1.00
373_R	377_S	2.055	1.00
135_A	354_E	2.050	1.00
137_Q	188_M	2.042	1.00
312_Q	341_N	2.013	1.00
140_I	184_H	2.005	1.00
45_K	49_D	1.980	1.00
138_Q	358_R	1.968	1.00
145_K	149_E	1.953	1.00
142_S	357_S	1.928	1.00
189_N	193_Y	1.927	1.00
145_K	362_D	1.925	1.00
370_K	374_Y	1.919	1.00
263_G	306_T	1.897	1.00
221_E	225_I	1.894	1.00
57_D	91_V	1.883	1.00
257_V	314_V	1.854	1.00
184_H	188_M	1.850	1.00
136_L	255_I	1.846	1.00
418_D	422_N	1.842	1.00
49_D	53_K	1.839	1.00
28_V	126_A	1.836	1.00
405_M	413_E	1.834	1.00
186_Q	247_L	1.831	1.00
142_S	361_I	1.828	1.00
91_V	95_Y	1.790	1.00
197_L	223_N	1.764	1.00
372_K	428_S	1.764	1.00
189_N	192_E	1.761	1.00
408_R	422_N	1.759	1.00
144_N	181_Q	1.753	1.00
31_K	52_I	1.732	1.00
420_E	423_K	1.727	1.00
150_Y	153_V	1.724	1.00
393_K	396_E	1.721	1.00
426_D	429_K	1.700	1.00
400_K	414_L	1.678	1.00
259_L	306_T	1.654	1.00
183_E	258_D	1.653	1.00
140_I	177_A	1.651	1.00
357_S	362_D	1.651	1.00
368_V	372_K	1.632	1.00
48_A	52_I	1.621	1.00
35_K	221_E	1.614	1.00
182_H	237_R	1.608	1.00
412_R	418_D	1.535	1.00
138_Q	357_S	1.521	1.00
220_N	224_R	1.519	1.00
199_I	218_V	1.518	1.00
405_M	410_A	1.505	1.00
36_V	221_E	1.497	1.00
147_A	177_A	1.488	1.00
135_A	350_S	1.478	1.00
319_A	337_L	1.469	1.00
201_G	238_A	1.463	1.00
146_K	150_Y	1.456	1.00
246_L	324_S	1.452	1.00
57_D	98_L	1.451	1.00
182_H	243_T	1.444	1.00
403_K	410_A	1.440	1.00
389_I	397_I	1.424	1.00
400_K	403_K	1.421	1.00
190_I	251_A	1.420	1.00
192_E	229_G	1.419	1.00
84_V	88_I	1.373	1.00
303_V	360_V	1.368	1.00
96_S	99_K	1.366	1.00
358_R	362_D	1.362	1.00
369_E	373_R	1.347	1.00
127_E	350_S	1.341	1.00
24_W	28_V	1.340	1.00
242_L	335_I	1.339	1.00
144_N	148_E	1.338	1.00
185_E	193_Y	1.320	1.00
367_N	370_K	1.319	1.00
31_K	35_K	1.311	1.00
138_Q	362_D	1.304	1.00
253_R	321_Q	1.300	1.00
268_L	328_E	1.299	1.00
263_G	356_M	1.295	1.00
82_M	85_N	1.294	1.00
250_G	254_N	1.291	1.00
410_A	414_L	1.290	1.00
133_L	191_L	1.289	1.00
246_L	254_N	1.279	1.00
124_A	248_L	1.278	1.00
318_H	322_F	1.271	1.00
21_R	127_E	1.270	1.00
140_I	180_F	1.268	1.00
406_S	409_E	1.266	1.00
169_L	173_L	1.260	1.00
173_L	176_Y	1.255	1.00
176_Y	330_E	1.242	1.00
27_G	58_L	1.236	1.00
34_A	43_L	1.236	1.00
142_S	145_K	1.234	1.00
136_L	180_F	1.213	1.00
26_M	115_T	1.211	1.00
219_I	223_N	1.205	1.00
153_V	368_V	1.191	1.00
42_L	108_F	1.183	1.00
50_S	53_K	1.182	1.00
144_N	177_A	1.171	1.00
148_E	151_K	1.163	1.00
312_Q	344_T	1.163	1.00
187_V	255_I	1.160	1.00
109_G	210_S	1.159	1.00
387_P	420_E	1.152	1.00
405_M	414_L	1.152	1.00
16_T	344_T	1.151	1.00
163_D	276_G	1.144	1.00
278_N	370_K	1.141	1.00
27_G	84_V	1.140	1.00
223_N	229_G	1.133	1.00
93_S	97_N	1.130	1.00
169_L	371_M	1.130	1.00
124_A	342_I	1.128	1.00
150_Y	368_V	1.127	1.00
135_A	138_Q	1.126	1.00
74_T	85_N	1.124	1.00
109_G	211_H	1.124	1.00
268_L	277_L	1.123	1.00
151_K	170_G	1.121	1.00
139_I	180_F	1.118	1.00
135_A	357_S	1.115	1.00
45_K	48_A	1.114	1.00
405_M	409_E	1.104	1.00
29_L	115_T	1.104	1.00
389_I	394_A	1.103	1.00
320_N	342_I	1.103	1.00
306_T	352_A	1.098	1.00
143_L	262_L	1.097	1.00
155_K	371_M	1.094	1.00
32_S	225_I	1.086	1.00
266_I	303_V	1.083	1.00
133_L	137_Q	1.082	1.00
138_Q	354_E	1.082	1.00
125_V	228_L	1.081	1.00
176_Y	262_L	1.080	1.00
128_V	191_L	1.074	1.00
245_L	342_I	1.073	1.00
315_G	319_A	1.070	1.00
83_N	86_E	1.068	1.00
52_I	56_D	1.068	1.00
137_Q	141_S	1.066	1.00
280_I	364_M	1.056	1.00
49_D	52_I	1.054	1.00
185_E	192_E	1.048	1.00
94_S	97_N	1.048	1.00
393_K	416_Y	1.046	1.00
118_T	197_L	1.044	1.00
408_R	412_R	1.042	1.00
39_D	225_I	1.042	1.00
153_V	371_M	1.042	1.00
139_I	361_I	1.040	1.00
50_S	54_A	1.036	1.00
69_L	72_F	1.035	1.00
166_P	375_A	1.034	1.00
53_K	95_Y	1.031	1.00
152_D	170_G	1.026	1.00
310_S	314_V	1.025	1.00
157_G	167_V	1.025	1.00
411_L	414_L	1.023	1.00
25_S	122_I	1.021	1.00
120_I	339_G	1.020	1.00
131_R	350_S	1.017	1.00
24_W	126_A	1.016	1.00
174_S	234_N	1.016	1.00
127_E	131_R	1.016	1.00
251_A	255_I	1.015	1.00
409_E	413_E	1.014	1.00
195_K	228_L	1.011	1.00
196_E	230_F	1.010	1.00
28_V	225_I	1.009	1.00
167_V	204_T	1.009	1.00
20_R	24_W	1.007	1.00
120_I	245_L	1.006	1.00
146_K	361_I	1.005	1.00
314_V	322_F	1.004	1.00
92_A	100_V	1.003	1.00
260_Y	307_L	0.997	1.00
249_S	320_N	0.992	1.00
146_K	173_L	0.990	1.00
191_L	195_K	0.989	1.00
388_V	424_I	0.988	1.00
125_V	191_L	0.986	1.00
160_H	304_E	0.981	1.00
268_L	329_F	0.979	1.00
151_K	168_T	0.977	1.00
259_L	353_L	0.967	1.00
410_A	413_E	0.966	1.00
54_A	57_D	0.964	1.00
136_L	184_H	0.959	1.00
178_D	182_H	0.957	1.00
248_L	342_I	0.956	1.00
419_N	423_K	0.956	1.00
172_E	330_E	0.954	1.00
196_E	231_K	0.954	1.00
278_N	367_N	0.953	1.00
266_I	364_M	0.951	1.00
388_V	420_E	0.951	1.00
44_D	105_H	0.947	1.00
13_N	305_A	0.946	1.00
38_A	49_D	0.939	1.00
168_T	431_V	0.939	1.00
50_S	102_P	0.936	1.00
128_V	187_V	0.932	1.00
26_M	29_L	0.925	1.00
189_N	247_L	0.925	1.00
40_L	211_H	0.923	1.00
185_E	189_N	0.922	1.00
96_S	103_N	0.922	1.00
70_D	74_T	0.917	1.00
403_K	414_L	0.917	1.00
29_L	118_T	0.915	1.00
67_I	73_Q	0.910	1.00
143_L	173_L	0.900	1.00
158_R	276_G	0.900	1.00
375_A	427_L	0.900	1.00
21_R	126_A	0.897	1.00
197_L	222_I	0.896	1.00
71_V	93_S	0.896	1.00
140_I	144_N	0.886	1.00
36_V	40_L	0.884	1.00
312_Q	340_Y	0.881	1.00
153_V	366_A	0.880	1.00
25_S	123_A	0.880	1.00
55_S	58_L	0.878	1.00
158_R	163_D	0.877	1.00
385_V	388_V	0.877	1.00
149_E	365_V	0.874	1.00
46_K	49_D	0.872	1.00
47_I	51_I	0.870	1.00
147_A	174_S	0.859	1.00
400_K	410_A	0.858	1.00
317_D	321_Q	0.856	1.00
47_I	100_V	0.851	1.00
163_D	275_T	0.847	1.00
249_S	317_D	0.847	1.00
67_I	72_F	0.845	1.00
250_G	317_D	0.845	1.00
218_V	223_N	0.844	1.00
101_H	104_D	0.843	1.00
408_R	418_D	0.839	1.00
161_L	268_L	0.838	1.00
249_S	342_I	0.837	1.00
68_V	71_V	0.835	1.00
28_V	222_I	0.832	1.00
26_M	84_V	0.831	1.00
167_V	236_F	0.831	1.00
143_L	361_I	0.830	1.00
154_I	375_A	0.828	1.00
82_M	86_E	0.826	1.00
406_S	410_A	0.824	1.00
154_I	431_V	0.824	1.00
171_Q	235_R	0.824	1.00
53_K	57_D	0.823	1.00
255_I	353_L	0.822	1.00
33_C	110_Q	0.821	1.00
177_A	181_Q	0.820	1.00
354_E	358_R	0.819	1.00
36_V	218_V	0.818	1.00
141_S	145_K	0.817	1.00
126_A	130_N	0.816	1.00
85_N	88_I	0.814	1.00
316_L	344_T	0.812	1.00
318_H	321_Q	0.811	1.00
340_Y	344_T	0.810	1.00
400_K	413_E	0.807	1.00
257_V	324_S	0.806	1.00
178_D	233_A	0.803	1.00
306_T	356_M	0.802	1.00
262_L	356_M	0.802	1.00
39_D	45_K	0.800	1.00
163_D	378_S	0.800	1.00
312_Q	316_L	0.799	1.00
142_S	146_K	0.799	1.00
143_L	177_A	0.798	1.00
120_I	342_I	0.798	1.00
198_P	238_A	0.798	1.00
34_A	48_A	0.796	0.99
69_L	73_Q	0.794	0.99
247_L	250_G	0.794	0.99
196_E	244_D	0.793	0.99
241_L	258_D	0.791	0.99
182_H	196_E	0.789	0.99
150_Y	366_A	0.779	0.99
314_V	318_H	0.778	0.99
91_V	94_S	0.777	0.99
260_Y	325_M	0.775	0.99
172_E	269_M	0.775	0.99
47_I	102_P	0.774	0.99
396_E	400_K	0.773	0.99
240_R	330_E	0.766	0.99
94_S	98_L	0.762	0.99
156_A	275_T	0.761	0.99
257_V	321_Q	0.758	0.99
360_V	364_M	0.758	0.99
202_T	293_I	0.755	0.99
35_K	39_D	0.754	0.99
311_A	323_A	0.753	0.99
376_E	408_R	0.753	0.99
38_A	43_L	0.747	0.99
31_K	225_I	0.747	0.99
51_I	55_S	0.745	0.99
248_L	347_N	0.744	0.99
155_K	172_E	0.744	0.99
286_E	363_G	0.743	0.99
223_N	231_K	0.742	0.99
149_E	368_V	0.741	0.99
192_E	195_K	0.738	0.99
68_V	72_F	0.737	0.99
152_D	428_S	0.735	0.99
22_I	116_V	0.734	0.99
125_V	130_N	0.727	0.99
233_A	238_A	0.724	0.99
65_D	68_V	0.724	0.99
263_G	303_V	0.723	0.99
323_A	337_L	0.723	0.99
128_V	190_I	0.722	0.99
136_L	353_L	0.719	0.99
46_K	50_S	0.718	0.99
31_K	48_A	0.717	0.99
243_T	258_D	0.716	0.99
180_F	353_L	0.716	0.99
34_A	51_I	0.715	0.99
143_L	180_F	0.710	0.99
51_I	102_P	0.710	0.99
353_L	357_S	0.709	0.99
319_A	341_N	0.707	0.99
421_I	425_L	0.705	0.99
311_A	319_A	0.704	0.99
236_F	330_E	0.703	0.99
423_K	429_K	0.703	0.99
314_V	321_Q	0.703	0.99
32_S	35_K	0.701	0.99
248_L	252_L	0.700	0.99
153_V	168_T	0.700	0.99
366_A	371_M	0.698	0.99
179_A	241_L	0.696	0.99
412_R	422_N	0.695	0.99
89_A	93_S	0.695	0.99
141_S	144_N	0.695	0.99
389_I	393_K	0.695	0.99
419_N	422_N	0.693	0.99
269_M	329_F	0.693	0.99
93_S	96_S	0.688	0.99
402_N	414_L	0.688	0.99
90_E	93_S	0.687	0.99
180_F	183_E	0.686	0.99
420_E	424_I	0.686	0.99
179_A	258_D	0.686	0.99
199_I	222_I	0.685	0.98
369_E	372_K	0.683	0.98
402_N	410_A	0.683	0.98
237_R	243_T	0.682	0.98
39_D	211_H	0.682	0.98
173_L	371_M	0.680	0.98
316_L	346_V	0.680	0.98
312_Q	348_F	0.676	0.98
260_Y	326_L	0.674	0.98
175_A	261_R	0.673	0.98
264_Q	307_L	0.672	0.98
13_N	17_K	0.670	0.98
428_S	432_K	0.669	0.98
18_F	340_Y	0.668	0.98
262_L	361_I	0.666	0.98
131_R	135_A	0.666	0.98
257_V	325_M	0.664	0.98
147_A	151_K	0.664	0.98
153_V	372_K	0.663	0.98
185_E	188_M	0.661	0.98
405_M	411_L	0.660	0.98
145_K	148_E	0.659	0.98
409_E	418_D	0.658	0.98
43_L	108_F	0.657	0.98
150_Y	169_L	0.656	0.98
130_N	228_L	0.656	0.98
132_L	346_V	0.656	0.98
183_E	254_N	0.655	0.98
125_V	229_G	0.655	0.98
57_D	95_Y	0.654	0.98
390_G	393_K	0.651	0.98
260_Y	322_F	0.650	0.98
38_A	52_I	0.649	0.98
87_V	90_E	0.648	0.98
34_A	106_V	0.647	0.98
342_I	346_V	0.646	0.98
155_K	167_V	0.645	0.98
156_A	375_A	0.645	0.98
195_K	223_N	0.644	0.98
137_Q	181_Q	0.644	0.98
139_I	357_S	0.643	0.98
319_A	323_A	0.642	0.98
42_L	211_H	0.639	0.98
70_D	73_Q	0.638	0.98
40_L	221_E	0.638	0.98
132_L	350_S	0.637	0.98
128_V	133_L	0.637	0.98
71_V	74_T	0.637	0.98
186_Q	243_T	0.636	0.98
302_T	356_M	0.634	0.98
17_K	127_E	0.633	0.97
148_E	152_D	0.631	0.97
138_Q	142_S	0.630	0.97
27_G	55_S	0.629	0.97
101_H	392_D	0.629	0.97
127_E	346_V	0.628	0.97
121_R	244_D	0.628	0.97
404_G	410_A	0.627	0.97
137_Q	140_I	0.627	0.97
128_V	194_V	0.625	0.97
396_E	414_L	0.621	0.97
123_A	346_V	0.621	0.97
86_E	89_A	0.620	0.97
190_I	248_L	0.619	0.97
246_L	250_G	0.617	0.97
142_S	358_R	0.616	0.97
259_L	357_S	0.615	0.97
253_R	257_V	0.614	0.97
134_P	138_Q	0.613	0.97
255_I	349_I	0.613	0.97
139_I	353_L	0.613	0.97
132_L	252_L	0.612	0.97
35_K	48_A	0.611	0.97
397_I	411_L	0.611	0.97
237_R	258_D	0.609	0.97
245_L	320_N	0.609	0.97
203_A	293_I	0.608	0.97
102_P	105_H	0.607	0.97
423_K	426_D	0.607	0.97
42_L	109_G	0.606	0.97
246_L	320_N	0.604	0.97
48_A	51_I	0.603	0.97
370_K	377_S	0.603	0.97
306_T	360_V	0.603	0.97
178_D	234_N	0.602	0.97
190_I	194_V	0.601	0.97
88_I	92_A	0.600	0.97
47_I	50_S	0.597	0.96
324_S	335_I	0.596	0.96
376_E	406_S	0.596	0.96
395_T	399_K	0.594	0.96
286_E	358_R	0.592	0.96
67_I	90_E	0.592	0.96
43_L	51_I	0.591	0.96
186_Q	189_N	0.591	0.96
222_I	225_I	0.590	0.96
180_F	255_I	0.589	0.96
168_T	432_K	0.588	0.96
375_A	380_S	0.587	0.96
408_R	414_L	0.586	0.96
374_Y	377_S	0.584	0.96
183_E	186_Q	0.582	0.96
105_H	108_F	0.581	0.96
55_S	88_I	0.581	0.96
248_L	346_V	0.580	0.96
187_V	251_A	0.580	0.96
29_L	199_I	0.579	0.96
181_Q	185_E	0.579	0.96
176_Y	179_A	0.578	0.96
16_T	340_Y	0.578	0.96
341_N	344_T	0.576	0.96
307_L	334_G	0.576	0.96
29_L	119_A	0.575	0.96
368_V	371_M	0.574	0.96
408_R	411_L	0.573	0.96
250_G	253_R	0.573	0.96
144_N	147_A	0.573	0.96
252_L	349_I	0.572	0.95
155_K	269_M	0.572	0.95
195_K	230_F	0.570	0.95
146_K	364_M	0.569	0.95
85_N	89_A	0.565	0.95
180_F	259_L	0.563	0.95
220_N	223_N	0.561	0.95
400_K	405_M	0.561	0.95
28_V	226_T	0.558	0.95
28_V	32_S	0.557	0.95
132_L	349_I	0.557	0.95
25_S	28_V	0.557	0.95
379_P	382_I	0.557	0.95
43_L	47_I	0.554	0.95
124_A	194_V	0.554	0.95
186_Q	193_Y	0.554	0.95
58_L	88_I	0.553	0.95
179_A	240_R	0.552	0.95
197_L	231_K	0.551	0.94
302_T	360_V	0.549	0.94
277_L	374_Y	0.549	0.94
417_S	422_N	0.549	0.94
167_V	171_Q	0.549	0.94
403_K	413_E	0.549	0.94
192_E	196_E	0.549	0.94
133_L	251_A	0.549	0.94
218_V	221_E	0.545	0.94
136_L	187_V	0.545	0.94
253_R	318_H	0.543	0.94
263_G	307_L	0.542	0.94
309_I	348_F	0.542	0.94
16_T	21_R	0.541	0.94
172_E	265_D	0.541	0.94
311_A	322_F	0.541	0.94
403_K	411_L	0.541	0.94
192_E	231_K	0.540	0.94
264_Q	326_L	0.540	0.94
392_D	396_E	0.540	0.94
243_T	246_L	0.539	0.94
163_D	380_S	0.538	0.94
68_V	73_Q	0.538	0.94
183_E	251_A	0.537	0.94
51_I	95_Y	0.537	0.94
190_I	247_L	0.536	0.94
178_D	181_Q	0.536	0.94
247_L	254_N	0.532	0.93
67_I	94_S	0.532	0.93
185_E	196_E	0.532	0.93
429_K	432_K	0.531	0.93
128_V	195_K	0.531	0.93
416_Y	420_E	0.529	0.93
154_I	427_L	0.528	0.93
270_F	280_I	0.526	0.93
252_L	255_I	0.525	0.93
256_A	349_I	0.525	0.93
186_Q	254_N	0.524	0.93
121_R	245_L	0.524	0.93
249_S	345_Q	0.523	0.93
156_A	374_Y	0.523	0.93
182_H	247_L	0.522	0.93
160_H	333_M	0.522	0.93
139_I	358_R	0.520	0.93
339_G	343_V	0.519	0.93
174_S	177_A	0.519	0.93
404_G	411_L	0.518	0.92
173_L	364_M	0.518	0.92
223_N	228_L	0.517	0.92
139_I	142_S	0.517	0.92
412_R	421_I	0.515	0.92
218_V	222_I	0.515	0.92
428_S	431_V	0.514	0.92
252_L	313_V	0.514	0.92
385_V	389_I	0.514	0.92
21_R	131_R	0.513	0.92
48_A	55_S	0.513	0.92
198_P	239_M	0.511	0.92
38_A	44_D	0.508	0.92
33_C	222_I	0.508	0.92
23_I	87_V	0.508	0.92
93_S	99_K	0.507	0.92
133_L	136_L	0.506	0.92
407_I	414_L	0.506	0.92
161_L	328_E	0.504	0.91
266_I	361_I	0.503	0.91
164_A	204_T	0.503	0.91
69_L	87_V	0.502	0.91
110_Q	115_T	0.502	0.91
188_M	192_E	0.501	0.91
34_A	52_I	0.500	0.91
43_L	48_A	0.500	0.91

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1furA	4	0.9703	100	0.153	Contact Map
1vdkA	4	0.9795	100	0.157	Contact Map
1yfmA	4	0.9658	100	0.16	Contact Map
3gtdA	4	0.9726	100	0.161	Contact Map
4hgvA	4	0.984	100	0.162	Contact Map
4admA	4	0.9772	100	0.164	Contact Map
3e04A	4	0.984	100	0.167	Contact Map
1jswA	4	0.9658	100	0.167	Contact Map
3r6qA	4	0.9863	100	0.169	Contact Map
3ocfA	4	0.9498	100	0.171	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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