GREMLIN Database
RS10 - 30S ribosomal protein S10
UniProt: P35027 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_01
Length: 102 (98)
Sequences: 1029 (438)
Seq/√Len: 44.2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
6_R75_D5.6601.00
49_P64_K4.0341.00
52_R61_K3.9751.00
31_T82_V3.9201.00
46_L69_V3.8081.00
49_P62_W2.6621.00
11_S17_L2.6601.00
51_M54_P2.2701.00
53_L57_E2.0650.99
22_T26_G1.9730.99
51_M55_H1.6580.97
17_L21_I1.5850.96
14_V18_N1.5530.96
53_L56_G1.4630.94
41_L73_L1.4580.94
21_I36_R1.4410.94
51_M60_K1.4310.94
39_I88_R1.4000.93
34_E77_A1.3640.92
92_P97_I1.3570.92
45_K68_R1.3020.90
51_M61_K1.2860.89
7_I68_R1.2840.89
61_K65_W1.2750.89
27_I30_K1.2740.89
51_M69_V1.2360.87
7_I76_I1.2190.87
53_L59_R1.2100.86
39_I73_L1.2070.86
56_G60_K1.1980.86
26_G30_K1.1950.86
46_L67_M1.1810.85
36_R67_M1.1590.84
46_L49_P1.1450.83
23_Q90_R1.1380.83
43_T70_H1.1200.82
53_L60_K1.1200.82
4_K36_R1.1160.81
44_S71_K1.1140.81
4_K17_L1.1090.81
51_M56_G1.1020.81
9_L17_L1.0880.80
39_I71_K1.0460.77
71_K74_I1.0250.76
28_V74_I1.0180.75
8_R44_S0.9980.74
54_P57_E0.9880.73
47_E64_K0.9860.73
11_S90_R0.9800.72
9_L101_L0.9750.72
53_L61_K0.9740.72
46_L50_I0.9510.70
24_I100_Q0.9460.69
25_R29_E0.9450.69
80_E87_M0.9390.69
76_I82_V0.9340.68
44_S57_E0.9150.67
9_L95_V0.9000.66
52_R65_W0.8640.62
3_T101_L0.8330.60
16_N34_E0.8100.57
22_T79_D0.8040.57
96_Y101_L0.8030.57
27_I87_M0.8020.57
46_L56_G0.7990.56
30_K70_H0.7960.56
17_L20_V0.7920.56
27_I89_V0.7720.54
38_P72_R0.7610.53
23_Q88_R0.7610.53
36_R92_P0.7600.53
86_L100_Q0.7510.52
40_P72_R0.7510.52
51_M62_W0.7500.52
31_T86_L0.7480.51
85_Q88_R0.7470.51
56_G62_W0.7410.51
52_R55_H0.7370.50
14_V70_H0.7360.50
48_V69_V0.7340.50
48_V67_M0.7330.50
11_S44_S0.7330.50
26_G101_L0.7220.49
69_V79_D0.7200.49
53_L66_E0.7120.48
16_N20_V0.7040.47
33_I99_I0.6950.46
23_Q29_E0.6940.46
13_N18_N0.6940.46
46_L71_K0.6910.46
8_R15_E0.6910.46
75_D89_V0.6910.46
54_P87_M0.6890.46
12_T44_S0.6780.45
67_M71_K0.6760.45
33_I82_V0.6740.44
87_M98_E0.6640.43
74_I84_R0.6640.43
4_K73_L0.6620.43
17_L67_M0.6580.43
8_R71_K0.6570.43
83_M87_M0.6560.43
18_N40_P0.6540.42
17_L70_H0.6510.42
36_R74_I0.6430.41
57_E60_K0.6380.41
81_R97_I0.6290.40
38_P42_P0.6260.40
17_L81_R0.6200.39
55_H62_W0.6100.38
55_H59_R0.6040.38
33_I79_D0.6030.38
11_S67_M0.6020.38
21_I25_R0.6010.38
74_I78_A0.5950.37
13_N94_D0.5910.37
89_V100_Q0.5870.36
28_V73_L0.5830.36
4_K101_L0.5700.35
13_N16_N0.5700.35
24_I27_I0.5690.35
11_S15_E0.5680.35
19_Y29_E0.5680.35
48_V56_G0.5680.35
15_E18_N0.5660.34
19_Y96_Y0.5630.34
69_V73_L0.5610.34
79_D95_V0.5560.34
43_T51_M0.5550.33
26_G60_K0.5520.33
25_R35_M0.5460.33
22_T95_V0.5440.33
48_V51_M0.5420.32
39_I75_D0.5370.32
49_P55_H0.5250.31
28_V86_L0.5240.31
10_W98_E0.5230.31
35_M95_V0.5230.31
19_Y23_Q0.5200.31
31_T81_R0.5170.30
87_M97_I0.5140.30
50_I56_G0.5140.30
28_V76_I0.5120.30
4_K75_D0.5100.30
26_G98_E0.5030.29
57_E71_K0.5030.29
47_E68_R0.5000.29
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3j20L 1 0.9902 100 0.18 Contact Map
3j7aN 1 0.9412 100 0.191 Contact Map
4ujpV 1 1 100 0.196 Contact Map
3j60U 1 1 100 0.196 Contact Map
4bpeJ 1 1 100 0.203 Contact Map
3zeyQ 1 1 100 0.205 Contact Map
3bbnJ 1 0.9608 100 0.21 Contact Map
4w23U 1 1 100 0.214 Contact Map
3w1yC 1 0.8725 100 0.232 Contact Map
4rb5J 1 0.9412 100 0.233 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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