EF2 - SULSO - GREMLIN Contacts

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EF2 - Elongation factor 2

UniProt:	P30925	Sequences: MPRYKTVEQVLSLMKDRTRVRNIGIIAHVDHGKTTTSDTLLAASGIISPKVAGEALALDYLNVEQQRGITVKAANISLYHEAEGKGYVINLIDTPGHVDFSGRVTRSLRVLDGSIVVVDAVEGIMTQTETVLRQSLEERVRPILFINKVDRLVKELKLSPQEMLNRLLDIIRQVNNLIDMYGEPEFKEKWMINPQAGNVIFGSAKDKWGFSLPMAQKKGINMKNVIDAYTASDKSKLEELAAQAPINEALLDAAIKFVPNPIEAQKYRIPKIWKGDLDNELAKAMLNADPNGPIVFMITDMKVDPHAGLVATGRVFSGTLRSGEELWLVNAKTSQRILQVSLYMGPTRELAEEIPAGNIAAVLGLDRARSGETAISVGFSNVQGSFERLHYISEPVVTIAVEPKNPKDLTKMIDALRKLSIEDPNLVVKINEETGEYLLSGMGFLHLEVSLQLLRENYGIDVVTTPPIVVYRESIRAKSQVFEGKSPNKHNKFYLSVEPLNDKTIELISNGTIREDMDSKEMAKILRDEASWDYDEAKRIIAIDENVNVFVDLTSGVQHLREVMDTVLQGFRLAMKEGPLAHEPIRGVKVILHDAVIHEDPAHRGPAQIYPAVRNSIFAGFLTSRPTLLEPIQKLDIRVPADLIGNVTAVITRKRGKILDVSQIANMSRITAEIPVSESYDMASELRGSTGGRAFWGTEFSRWAPVPDSILLDVVTKIRERKGLPKELPKVEDFLS	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	736 (695)
Sequences:	1337 (793)
Seq/√Len:	30.1

ECOLI - EFG LEPA TYPA RF3
BACSU - EFG LEPA TYPA
HALSA - EF2
SULSO - EF2

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
354_I	360_A	6.279	1.00
120_A	146_I	5.788	1.00
368_A	371_G	5.472	1.00
321_R	353_E	5.366	1.00
368_A	372_E	4.999	1.00
320_L	362_V	4.468	1.00
444_F	681_D	3.814	1.00
27_A	30_D	3.711	1.00
455_R	461_D	3.629	1.00
590_V	617_I	3.494	1.00
131_V	134_Q	3.492	1.00
354_I	358_N	3.436	1.00
41_L	76_I	3.410	1.00
145_F	202_G	3.364	1.00
369_R	372_E	3.364	1.00
24_G	111_L	3.261	1.00
62_N	66_Q	3.241	1.00
261_P	268_R	3.222	1.00
426_L	450_S	3.145	1.00
452_Q	456_E	3.010	1.00
296_F	320_L	2.972	1.00
60_Y	74_A	2.950	1.00
259_P	268_R	2.926	1.00
637_I	647_V	2.926	1.00
253_A	259_P	2.922	1.00
507_L	530_A	2.843	1.00
151_R	155_E	2.836	1.00
633_Q	676_V	2.823	1.00
284_A	292_G	2.821	1.00
674_I	682_M	2.760	1.00
118_V	144_L	2.755	1.00
340_V	362_V	2.740	1.00
28_H	31_H	2.669	1.00
234_K	237_L	2.631	1.00
257_F	261_P	2.628	1.00
258_V	261_P	2.624	1.00
252_D	259_P	2.539	0.99
474_S	627_T	2.499	0.99
397_V	680_Y	2.481	0.99
192_I	198_N	2.463	0.99
613_V	617_I	2.445	0.99
415_A	454_L	2.429	0.99
622_L	626_P	2.394	0.99
250_L	258_V	2.371	0.99
75_N	359_I	2.332	0.99
627_T	710_I	2.322	0.99
451_L	455_R	2.305	0.99
23_I	254_A	2.294	0.99
253_A	257_F	2.271	0.99
298_I	311_A	2.233	0.99
471_Y	677_S	2.223	0.99
252_D	261_P	2.191	0.98
487_P	612_A	2.185	0.98
250_L	259_P	2.180	0.98
713_D	717_K	2.179	0.98
496_S	593_H	2.179	0.98
37_S	58_L	2.160	0.98
285_M	288_A	2.147	0.98
296_F	315_V	2.138	0.98
108_L	114_S	2.113	0.98
325_E	334_S	2.097	0.98
294_I	326_L	2.048	0.97
616_S	620_G	2.046	0.97
687_R	692_G	2.041	0.97
234_K	241_A	2.041	0.97
26_I	114_S	2.028	0.97
187_K	190_W	2.015	0.97
342_L	351_A	2.010	0.97
36_T	250_L	2.007	0.97
712_L	716_T	1.993	0.97
527_R	534_Y	1.992	0.97
320_L	337_I	1.990	0.97
630_E	655_R	1.988	0.97
408_D	411_K	1.987	0.97
215_A	219_G	1.980	0.97
216_Q	219_G	1.971	0.97
250_L	261_P	1.927	0.96
634_K	671_T	1.896	0.96
351_A	354_I	1.892	0.96
585_I	621_F	1.874	0.96
540_I	549_V	1.874	0.96
365_L	374_A	1.854	0.95
296_F	362_V	1.853	0.95
25_I	31_H	1.847	0.95
283_K	286_L	1.844	0.95
22_N	25_I	1.842	0.95
200_I	253_A	1.832	0.95
16_D	19_R	1.829	0.95
131_V	135_S	1.826	0.95
25_I	117_V	1.810	0.95
250_L	257_F	1.806	0.95
120_A	167_L	1.806	0.95
124_I	128_T	1.786	0.94
261_P	265_Q	1.779	0.94
694_A	700_F	1.766	0.94
328_L	372_E	1.766	0.94
27_A	37_S	1.762	0.94
259_P	263_E	1.761	0.94
109_R	134_Q	1.760	0.94
257_F	263_E	1.755	0.94
36_T	117_V	1.755	0.94
194_P	210_F	1.750	0.94
504_T	526_L	1.750	0.94
295_V	375_I	1.747	0.94
261_P	264_A	1.734	0.93
143_I	258_V	1.729	0.93
497_V	590_V	1.726	0.93
254_A	261_P	1.722	0.93
252_D	263_E	1.720	0.93
488_N	491_N	1.718	0.93
194_P	201_F	1.716	0.93
264_A	268_R	1.714	0.93
653_R	685_E	1.712	0.93
74_A	345_G	1.710	0.93
471_Y	714_V	1.709	0.93
288_A	292_G	1.709	0.93
615_N	618_F	1.700	0.93
284_A	289_D	1.695	0.93
367_R	371_G	1.692	0.93
570_G	617_I	1.688	0.92
59_D	64_E	1.688	0.92
253_A	261_P	1.681	0.92
550_F	592_L	1.680	0.92
30_D	70_T	1.666	0.92
30_D	69_I	1.631	0.91
71_V	449_V	1.618	0.91
355_P	401_V	1.614	0.91
326_L	374_A	1.605	0.90
257_F	260_N	1.605	0.90
26_I	135_S	1.599	0.90
567_V	613_V	1.585	0.90
398_T	438_L	1.576	0.90
21_R	28_H	1.576	0.90
674_I	679_S	1.574	0.90
104_V	131_V	1.568	0.89
284_A	288_A	1.563	0.89
257_F	268_R	1.543	0.89
322_S	352_E	1.539	0.88
260_N	263_E	1.539	0.88
97_H	443_G	1.533	0.88
654_K	681_D	1.527	0.88
567_V	570_G	1.522	0.88
294_I	319_T	1.521	0.88
310_V	361_A	1.520	0.88
523_A	526_L	1.518	0.88
530_A	533_D	1.507	0.87
103_R	300_D	1.503	0.87
61_L	65_Q	1.499	0.87
512_T	529_E	1.488	0.87
109_R	138_E	1.486	0.87
502_D	506_E	1.482	0.86
651_I	656_G	1.480	0.86
423_D	446_H	1.458	0.86
285_M	292_G	1.451	0.85
268_R	272_I	1.447	0.85
259_P	265_Q	1.445	0.85
495_L	613_V	1.440	0.85
110_V	299_T	1.428	0.84
23_I	458_Y	1.424	0.84
585_I	595_A	1.423	0.84
146_I	170_I	1.418	0.84
76_I	344_M	1.416	0.84
258_V	263_E	1.415	0.84
101_S	127_Q	1.413	0.84
673_E	704_A	1.411	0.84
56_L	59_D	1.395	0.83
506_E	510_N	1.393	0.83
505_I	547_V	1.390	0.83
686_L	702_R	1.385	0.82
286_L	289_D	1.383	0.82
315_V	360_A	1.382	0.82
500_L	504_T	1.373	0.82
118_V	128_T	1.371	0.82
260_N	268_R	1.367	0.82
143_I	253_A	1.362	0.81
326_L	347_T	1.362	0.81
524_K	527_R	1.361	0.81
619_A	623_T	1.356	0.81
265_Q	268_R	1.354	0.81
250_L	253_A	1.354	0.81
570_G	574_A	1.347	0.81
261_P	280_E	1.346	0.81
259_P	264_A	1.337	0.80
579_P	621_F	1.336	0.80
339_Q	350_L	1.335	0.80
27_A	70_T	1.326	0.80
93_D	96_G	1.326	0.80
24_G	27_A	1.326	0.80
493_F	616_S	1.324	0.79
266_K	270_P	1.322	0.79
26_I	108_L	1.317	0.79
261_P	276_D	1.315	0.79
59_D	67_R	1.314	0.79
259_P	275_G	1.312	0.79
634_K	699_E	1.308	0.79
419_L	454_L	1.308	0.79
80_H	252_D	1.301	0.78
127_Q	134_Q	1.291	0.78
51_V	54_E	1.291	0.78
261_P	274_K	1.285	0.77
158_L	406_P	1.284	0.77
391_Y	425_N	1.281	0.77
54_E	65_Q	1.278	0.77
194_P	199_V	1.276	0.77
399_I	451_L	1.270	0.76
101_S	105_T	1.268	0.76
523_A	537_A	1.263	0.76
258_V	268_R	1.251	0.75
40_L	175_N	1.248	0.75
144_L	192_I	1.246	0.75
127_Q	130_T	1.246	0.75
495_L	616_S	1.243	0.75
536_E	551_V	1.232	0.74
399_I	465_T	1.229	0.74
250_L	260_N	1.229	0.74
386_F	389_L	1.228	0.74
56_L	67_R	1.226	0.74
289_D	293_P	1.221	0.74
129_E	135_S	1.217	0.73
251_L	254_A	1.212	0.73
52_A	56_L	1.210	0.73
320_L	340_V	1.209	0.73
474_S	629_L	1.209	0.73
27_A	32_G	1.203	0.72
444_F	654_K	1.200	0.72
30_D	33_K	1.198	0.72
37_S	91_L	1.197	0.72
597_I	602_A	1.195	0.72
28_H	74_A	1.193	0.72
117_V	320_L	1.191	0.72
367_R	370_S	1.191	0.72
70_T	127_Q	1.188	0.71
261_P	273_W	1.186	0.71
251_L	261_P	1.182	0.71
38_D	56_L	1.180	0.71
47_I	344_M	1.179	0.71
292_G	317_S	1.178	0.71
29_V	70_T	1.174	0.71
284_A	293_P	1.173	0.70
53_G	70_T	1.172	0.70
404_K	461_D	1.172	0.70
58_L	70_T	1.170	0.70
529_E	532_W	1.168	0.70
639_V	643_L	1.160	0.70
293_P	317_S	1.145	0.69
268_R	273_W	1.144	0.69
641_A	644_I	1.143	0.68
207_K	215_A	1.143	0.68
405_N	408_D	1.142	0.68
44_S	77_S	1.141	0.68
586_R	703_W	1.139	0.68
315_V	354_I	1.138	0.68
21_R	113_G	1.132	0.68
298_I	337_I	1.131	0.68
296_F	360_A	1.131	0.68
491_N	604_R	1.131	0.68
269_I	282_A	1.128	0.67
22_N	27_A	1.126	0.67
26_I	116_V	1.126	0.67
236_K	244_A	1.122	0.67
261_P	270_P	1.119	0.67
146_I	570_G	1.117	0.67
634_K	701_S	1.116	0.67
339_Q	363_L	1.113	0.66
650_V	682_M	1.111	0.66
485_K	489_K	1.103	0.66
534_Y	538_K	1.102	0.66
651_I	659_L	1.100	0.65
676_V	679_S	1.099	0.65
201_F	208_W	1.099	0.65
283_K	287_N	1.096	0.65
52_A	65_Q	1.095	0.65
281_L	288_A	1.092	0.65
367_R	372_E	1.092	0.65
552_D	606_P	1.091	0.65
63_V	452_Q	1.087	0.65
263_E	266_K	1.087	0.65
97_H	119_D	1.087	0.65
259_P	276_D	1.085	0.64
201_F	215_A	1.081	0.64
271_K	275_G	1.078	0.64
321_R	324_E	1.076	0.64
201_F	210_F	1.073	0.63
69_I	97_H	1.073	0.63
261_P	275_G	1.071	0.63
159_S	162_E	1.069	0.63
64_E	67_R	1.068	0.63
414_D	418_K	1.064	0.63
610_Y	614_R	1.063	0.63
250_L	254_A	1.062	0.63
567_V	609_I	1.061	0.63
59_D	69_I	1.060	0.63
198_N	201_F	1.055	0.62
677_S	714_V	1.055	0.62
250_L	266_K	1.054	0.62
523_A	592_L	1.052	0.62
31_H	118_V	1.050	0.62
255_I	264_A	1.050	0.62
498_E	589_K	1.047	0.62
553_L	591_I	1.047	0.62
121_V	151_R	1.044	0.61
35_T	140_V	1.039	0.61
20_V	90_N	1.037	0.61
258_V	280_E	1.037	0.61
525_I	529_E	1.037	0.61
250_L	268_R	1.035	0.61
61_L	680_Y	1.034	0.61
45_G	70_T	1.034	0.61
194_P	198_N	1.033	0.60
59_D	100_F	1.032	0.60
261_P	266_K	1.032	0.60
194_P	215_A	1.029	0.60
113_G	131_V	1.028	0.60
552_D	557_V	1.027	0.60
606_P	610_Y	1.023	0.60
259_P	266_K	1.021	0.60
105_T	134_Q	1.021	0.60
59_D	65_Q	1.020	0.59
256_K	272_I	1.019	0.59
419_L	426_L	1.018	0.59
295_V	383_Q	1.015	0.59
91_L	107_S	1.013	0.59
681_D	685_E	1.011	0.59
654_K	675_P	1.011	0.59
107_S	426_L	1.011	0.59
234_K	238_E	1.011	0.59
630_E	714_V	1.010	0.59
402_E	463_V	1.007	0.58
249_A	257_F	1.003	0.58
522_M	526_L	1.001	0.58
194_P	216_Q	0.999	0.58
59_D	68_G	0.999	0.58
90_N	101_S	0.998	0.58
79_Y	149_V	0.998	0.58
564_M	592_L	0.996	0.58
70_T	76_I	0.994	0.57
269_I	272_I	0.992	0.57
116_V	131_V	0.990	0.57
223_K	298_I	0.990	0.57
478_K	498_E	0.990	0.57
254_A	263_E	0.989	0.57
319_T	500_L	0.989	0.57
67_R	97_H	0.989	0.57
434_T	666_N	0.989	0.57
256_K	670_I	0.986	0.57
222_M	226_I	0.985	0.57
48_S	53_G	0.983	0.57
24_G	108_L	0.981	0.56
27_A	33_K	0.980	0.56
257_F	276_D	0.979	0.56
81_E	84_G	0.979	0.56
254_A	259_P	0.977	0.56
44_S	71_V	0.976	0.56
210_F	219_G	0.975	0.56
89_I	592_L	0.974	0.56
651_I	703_W	0.971	0.56
26_I	35_T	0.971	0.56
127_Q	131_V	0.971	0.56
266_K	271_K	0.970	0.56
250_L	263_E	0.969	0.56
251_L	258_V	0.967	0.55
38_D	59_D	0.963	0.55
143_I	234_K	0.960	0.55
24_G	30_D	0.959	0.55
56_L	65_Q	0.958	0.55
149_V	208_W	0.954	0.54
310_V	348_R	0.953	0.54
263_E	273_W	0.953	0.54
212_L	216_Q	0.953	0.54
444_F	680_Y	0.950	0.54
498_E	591_I	0.947	0.54
447_L	501_N	0.946	0.54
263_E	268_R	0.945	0.54
135_S	142_P	0.945	0.54
24_G	106_R	0.940	0.53
256_K	261_P	0.940	0.53
116_V	128_T	0.939	0.53
110_V	140_V	0.938	0.53
41_L	606_P	0.937	0.53
149_V	342_L	0.937	0.53
320_L	326_L	0.936	0.53
193_N	196_A	0.936	0.53
282_A	286_L	0.931	0.53
540_I	551_V	0.928	0.52
27_A	31_H	0.927	0.52
67_R	402_E	0.926	0.52
23_I	89_I	0.926	0.52
597_I	601_P	0.924	0.52
224_N	228_A	0.924	0.52
258_V	270_P	0.920	0.52
60_Y	63_V	0.919	0.52
231_A	237_L	0.916	0.51
133_R	661_V	0.915	0.51
341_S	363_L	0.915	0.51
98_V	130_T	0.914	0.51
657_K	704_A	0.910	0.51
592_L	658_I	0.909	0.51
58_L	448_E	0.908	0.51
146_I	389_L	0.907	0.51
234_K	240_L	0.906	0.51
64_E	70_T	0.906	0.51
199_V	203_S	0.905	0.50
32_G	35_T	0.903	0.50
88_V	358_N	0.903	0.50
101_S	107_S	0.903	0.50
192_I	613_V	0.902	0.50
252_D	257_F	0.901	0.50
268_R	274_K	0.900	0.50
20_V	481_V	0.900	0.50
251_L	257_F	0.899	0.50
494_Y	553_L	0.899	0.50
137_E	179_D	0.898	0.50
475_I	624_S	0.898	0.50
539_R	557_V	0.898	0.50
523_A	538_K	0.897	0.50
263_E	267_Y	0.897	0.50
204_A	208_W	0.896	0.50
45_G	251_L	0.887	0.49
31_H	38_D	0.887	0.49
191_M	195_Q	0.882	0.49
233_D	374_A	0.881	0.49
340_V	354_I	0.881	0.49
97_H	103_R	0.881	0.49
132_L	344_M	0.879	0.48
260_N	563_V	0.878	0.48
647_V	660_D	0.877	0.48
296_F	313_G	0.877	0.48
230_T	236_K	0.876	0.48
269_I	274_K	0.875	0.48
189_K	196_A	0.872	0.48
99_D	104_V	0.869	0.48
158_L	402_E	0.867	0.47
81_E	86_G	0.867	0.47
237_L	686_L	0.867	0.47
624_S	630_E	0.866	0.47
60_Y	65_Q	0.866	0.47
259_P	273_W	0.866	0.47
639_V	644_I	0.865	0.47
36_T	39_T	0.865	0.47
639_V	682_M	0.863	0.47
505_I	587_G	0.863	0.47
73_A	422_E	0.862	0.47
574_A	585_I	0.860	0.47
88_V	475_I	0.858	0.47
78_L	153_V	0.858	0.47
389_L	628_L	0.856	0.47
408_D	460_I	0.853	0.46
61_L	72_K	0.851	0.46
88_V	355_P	0.851	0.46
260_N	276_D	0.849	0.46
295_V	356_A	0.848	0.46
647_V	688_G	0.848	0.46
282_A	592_L	0.848	0.46
635_L	647_V	0.847	0.46
28_H	128_T	0.847	0.46
128_T	424_P	0.847	0.46
430_I	628_L	0.839	0.45
590_V	620_G	0.839	0.45
202_G	209_G	0.838	0.45
258_V	269_I	0.838	0.45
92_I	111_L	0.837	0.45
651_I	655_R	0.836	0.45
417_R	540_I	0.833	0.45
64_E	68_G	0.831	0.45
21_R	27_A	0.830	0.45
151_R	687_R	0.830	0.45
259_P	280_E	0.829	0.44
259_P	262_I	0.827	0.44
574_A	617_I	0.827	0.44
35_T	92_I	0.826	0.44
22_N	90_N	0.825	0.44
281_L	284_A	0.824	0.44
539_R	553_L	0.823	0.44
403_P	584_P	0.821	0.44
429_K	590_V	0.821	0.44
127_Q	423_D	0.821	0.44
269_I	276_D	0.820	0.44
326_L	495_L	0.816	0.43
326_L	337_I	0.815	0.43
89_I	358_N	0.814	0.43
271_K	277_L	0.814	0.43
96_G	99_D	0.813	0.43
226_I	240_L	0.812	0.43
211_S	252_D	0.810	0.43
255_I	372_E	0.809	0.43
503_K	506_E	0.806	0.43
210_F	215_A	0.803	0.42
34_T	68_G	0.802	0.42
566_T	606_P	0.801	0.42
27_A	127_Q	0.799	0.42
618_F	623_T	0.799	0.42
439_L	450_S	0.796	0.42
714_V	718_I	0.796	0.42
465_T	571_F	0.793	0.42
612_A	616_S	0.793	0.42
302_K	523_A	0.791	0.41
560_L	670_I	0.791	0.41
101_S	134_Q	0.791	0.41
143_I	321_R	0.790	0.41
259_P	267_Y	0.790	0.41
313_G	362_V	0.790	0.41
288_A	293_P	0.790	0.41
304_D	310_V	0.788	0.41
94_T	371_G	0.787	0.41
607_A	612_A	0.787	0.41
260_N	267_Y	0.787	0.41
74_A	121_V	0.786	0.41
57_A	68_G	0.786	0.41
635_L	682_M	0.785	0.41
635_L	698_T	0.785	0.41
122_E	148_K	0.785	0.41
97_H	100_F	0.783	0.41
241_A	245_P	0.783	0.41
186_F	191_M	0.781	0.41
25_I	37_S	0.780	0.41
574_A	592_L	0.780	0.41
26_I	37_S	0.779	0.41
64_E	443_G	0.778	0.40
635_L	672_A	0.776	0.40
72_K	686_L	0.776	0.40
593_H	616_S	0.775	0.40
491_N	611_P	0.775	0.40
570_G	579_P	0.775	0.40
523_A	527_R	0.774	0.40
199_V	208_W	0.773	0.40
39_T	43_A	0.773	0.40
93_D	97_H	0.772	0.40
686_L	695_F	0.772	0.40
258_V	273_W	0.771	0.40
539_R	551_V	0.771	0.40
31_H	36_T	0.771	0.40
412_M	628_L	0.768	0.40
523_A	534_Y	0.768	0.40
462_V	542_A	0.768	0.40
281_L	285_M	0.768	0.40
216_Q	544_D	0.767	0.40
73_A	92_I	0.767	0.40
252_D	258_V	0.766	0.40
258_V	267_Y	0.766	0.40
264_A	267_Y	0.766	0.40
217_K	289_D	0.764	0.39
478_K	496_S	0.764	0.39
408_D	555_S	0.763	0.39
541_I	564_M	0.760	0.39
259_P	274_K	0.760	0.39
269_I	277_L	0.759	0.39
167_L	171_I	0.758	0.39
97_H	148_K	0.757	0.39
398_T	717_K	0.757	0.39
513_I	525_I	0.756	0.39
254_A	269_I	0.755	0.39
573_L	608_Q	0.755	0.39
595_A	601_P	0.753	0.39
592_L	614_R	0.752	0.39
28_H	32_G	0.752	0.39
627_T	705_P	0.751	0.38
524_K	531_S	0.751	0.38
643_L	646_N	0.751	0.38
137_E	305_P	0.749	0.38
87_Y	255_I	0.748	0.38
224_N	585_I	0.746	0.38
75_N	385_S	0.745	0.38
488_N	601_P	0.745	0.38
54_E	68_G	0.745	0.38
67_R	443_G	0.745	0.38
250_L	270_P	0.744	0.38
96_G	443_G	0.743	0.38
362_V	592_L	0.742	0.38
19_R	391_Y	0.741	0.38
67_R	100_F	0.740	0.38
34_T	38_D	0.740	0.38
490_H	562_E	0.739	0.38
712_L	717_K	0.735	0.37
320_L	439_L	0.734	0.37
261_P	269_I	0.733	0.37
520_K	527_R	0.731	0.37
95_P	100_F	0.730	0.37
63_V	71_V	0.730	0.37
104_V	148_K	0.729	0.37
30_D	59_D	0.729	0.37
469_V	714_V	0.729	0.37
455_R	464_T	0.727	0.37
227_D	670_I	0.724	0.36
124_I	133_R	0.724	0.36
700_F	703_W	0.723	0.36
16_D	20_V	0.722	0.36
73_A	299_T	0.722	0.36
270_P	274_K	0.720	0.36
522_M	558_Q	0.720	0.36
475_I	541_I	0.720	0.36
461_D	478_K	0.718	0.36
486_S	489_K	0.718	0.36
281_L	286_L	0.717	0.36
316_F	493_F	0.715	0.36
145_F	359_I	0.715	0.36
51_V	107_S	0.714	0.36
315_V	454_L	0.713	0.36
332_K	501_N	0.713	0.36
201_F	231_A	0.713	0.36
143_I	200_I	0.713	0.36
178_I	192_I	0.712	0.36
204_A	584_P	0.712	0.36
129_E	133_R	0.710	0.35
340_V	351_A	0.710	0.35
52_A	70_T	0.709	0.35
359_I	387_E	0.709	0.35
600_D	603_H	0.709	0.35
45_G	76_I	0.709	0.35
132_L	142_P	0.709	0.35
455_R	458_Y	0.708	0.35
343_Y	389_L	0.707	0.35
114_S	656_G	0.706	0.35
460_I	493_F	0.706	0.35
627_T	709_S	0.705	0.35
321_R	352_E	0.705	0.35
255_I	259_P	0.704	0.35
78_L	91_L	0.704	0.35
157_K	223_K	0.704	0.35
712_L	718_I	0.704	0.35
639_V	647_V	0.702	0.35
67_R	98_V	0.700	0.35
19_R	85_K	0.700	0.35
257_F	264_A	0.699	0.35
46_I	76_I	0.698	0.35
230_T	240_L	0.698	0.35
462_V	498_E	0.698	0.35
255_I	261_P	0.696	0.34
257_F	262_I	0.696	0.34
44_S	656_G	0.695	0.34
326_L	417_R	0.694	0.34
495_L	617_I	0.694	0.34
300_D	312_T	0.693	0.34
429_K	684_S	0.693	0.34
238_E	241_A	0.692	0.34
522_M	525_I	0.691	0.34
670_I	717_K	0.691	0.34
322_S	350_L	0.691	0.34
23_I	471_Y	0.688	0.34
293_P	298_I	0.688	0.34
162_E	644_I	0.688	0.34
220_I	260_N	0.687	0.34
64_E	96_G	0.686	0.34
22_N	32_G	0.686	0.34
222_M	351_A	0.685	0.34
64_E	93_D	0.684	0.34
233_D	237_L	0.684	0.34
417_R	474_S	0.684	0.34
65_Q	68_G	0.684	0.34
634_K	659_L	0.682	0.33
601_P	604_R	0.681	0.33
67_R	687_R	0.680	0.33
130_T	565_D	0.679	0.33
285_M	289_D	0.679	0.33
376_S	462_V	0.679	0.33
475_I	533_D	0.678	0.33
686_L	692_G	0.678	0.33
704_A	716_T	0.677	0.33
437_Y	682_M	0.677	0.33
28_H	148_K	0.677	0.33
604_R	611_P	0.676	0.33
393_S	592_L	0.676	0.33
634_K	697_G	0.674	0.33
342_L	686_L	0.674	0.33
473_E	675_P	0.674	0.33
705_P	710_I	0.674	0.33
164_L	171_I	0.673	0.33
707_P	711_L	0.673	0.33
197_G	213_P	0.672	0.33
268_R	275_G	0.672	0.33
470_V	633_Q	0.670	0.33
410_T	611_P	0.670	0.33
434_T	468_I	0.670	0.33
77_S	399_I	0.669	0.32
41_L	345_G	0.669	0.32
22_N	34_T	0.668	0.32
419_L	450_S	0.667	0.32
294_I	359_I	0.667	0.32
289_D	292_G	0.667	0.32
532_W	541_I	0.665	0.32
295_V	298_I	0.665	0.32
200_I	211_S	0.664	0.32
404_K	430_I	0.664	0.32
88_V	258_V	0.664	0.32
149_V	167_L	0.664	0.32
97_H	151_R	0.663	0.32
402_E	447_L	0.663	0.32
24_G	29_V	0.663	0.32
477_A	625_R	0.663	0.32
230_T	237_L	0.662	0.32
59_D	99_D	0.662	0.32
70_T	73_A	0.660	0.32
276_D	384_G	0.660	0.32
491_N	565_D	0.660	0.32
268_R	276_D	0.659	0.32
106_R	111_L	0.658	0.32
127_Q	469_V	0.658	0.32
231_A	236_K	0.657	0.32
703_W	710_I	0.656	0.32
105_T	678_E	0.656	0.32
315_V	705_P	0.653	0.31
102_G	446_H	0.651	0.31
706_V	714_V	0.651	0.31
233_D	238_E	0.650	0.31
454_L	458_Y	0.650	0.31
636_D	669_R	0.650	0.31
489_K	609_I	0.649	0.31
503_K	527_R	0.649	0.31
647_V	670_I	0.649	0.31
340_V	617_I	0.648	0.31
26_I	131_V	0.648	0.31
414_D	417_R	0.647	0.31
215_A	628_L	0.646	0.31
252_D	509_S	0.645	0.31
300_D	453_L	0.645	0.31
339_Q	352_E	0.645	0.31
329_V	420_S	0.644	0.31
283_K	288_A	0.642	0.31
325_E	336_R	0.641	0.31
480_Q	716_T	0.640	0.30
91_L	94_T	0.639	0.30
544_D	550_F	0.638	0.30
298_I	321_R	0.637	0.30
258_V	276_D	0.637	0.30
98_V	234_K	0.636	0.30
96_G	100_F	0.636	0.30
439_L	649_A	0.634	0.30
23_I	104_V	0.634	0.30
439_L	584_P	0.633	0.30
423_D	449_V	0.632	0.30
162_E	165_N	0.632	0.30
328_L	475_I	0.632	0.30
471_Y	628_L	0.632	0.30
30_D	127_Q	0.631	0.30
475_I	626_P	0.631	0.30
79_Y	86_G	0.631	0.30
551_V	591_I	0.630	0.30
211_S	216_Q	0.629	0.30
486_S	601_P	0.629	0.30
94_T	426_L	0.628	0.30
58_L	65_Q	0.628	0.30
77_S	116_V	0.627	0.30
384_G	387_E	0.627	0.30
563_V	609_I	0.626	0.30
592_L	638_R	0.626	0.30
327_W	334_S	0.626	0.30
183_E	186_F	0.626	0.30
54_E	189_K	0.626	0.30
253_A	258_V	0.625	0.29
483_E	486_S	0.625	0.29
443_G	692_G	0.624	0.29
637_I	694_A	0.624	0.29
657_K	673_E	0.623	0.29
51_V	200_I	0.622	0.29
210_F	216_Q	0.620	0.29
430_I	659_L	0.620	0.29
613_V	670_I	0.620	0.29
663_Q	668_S	0.619	0.29
408_D	461_D	0.619	0.29
94_T	345_G	0.619	0.29
372_E	466_P	0.618	0.29
212_L	218_K	0.618	0.29
430_I	681_D	0.617	0.29
210_F	231_A	0.616	0.29
121_V	359_I	0.616	0.29
72_K	679_S	0.615	0.29
562_E	602_A	0.615	0.29
91_L	101_S	0.615	0.29
488_N	554_T	0.615	0.29
595_A	655_R	0.615	0.29
68_G	445_L	0.614	0.29
256_K	274_K	0.614	0.29
519_S	522_M	0.614	0.29
77_S	88_V	0.614	0.29
315_V	355_P	0.614	0.29
317_S	356_A	0.613	0.29
264_A	270_P	0.612	0.29
65_Q	345_G	0.612	0.29
70_T	99_D	0.612	0.29
234_K	582_H	0.612	0.29
469_V	606_P	0.612	0.29
57_A	346_P	0.611	0.29
495_L	592_L	0.610	0.29
365_L	368_A	0.610	0.29
348_R	396_V	0.610	0.29
401_V	451_L	0.609	0.28
104_V	134_Q	0.608	0.28
534_Y	637_I	0.608	0.28
356_A	579_P	0.607	0.28
26_I	29_V	0.607	0.28
538_K	541_I	0.607	0.28
537_A	543_I	0.607	0.28
194_P	197_G	0.606	0.28
304_D	348_R	0.606	0.28
145_F	200_I	0.605	0.28
24_G	65_Q	0.604	0.28
256_K	280_E	0.603	0.28
42_A	47_I	0.603	0.28
110_V	308_G	0.603	0.28
402_E	435_G	0.603	0.28
21_R	32_G	0.603	0.28
474_S	705_P	0.602	0.28
129_E	445_L	0.602	0.28
493_F	613_V	0.602	0.28
44_S	91_L	0.601	0.28
269_I	315_V	0.600	0.28
37_S	45_G	0.600	0.28
24_G	36_T	0.600	0.28
532_W	703_W	0.599	0.28
545_E	550_F	0.599	0.28
532_W	535_D	0.599	0.28
144_L	171_I	0.599	0.28
70_T	423_D	0.598	0.28
334_S	365_L	0.596	0.28
236_K	248_E	0.596	0.28
657_K	685_E	0.596	0.28
560_L	564_M	0.596	0.28
61_L	453_L	0.595	0.28
64_E	95_P	0.594	0.27
260_N	271_K	0.593	0.27
168_L	585_I	0.593	0.27
98_V	127_Q	0.593	0.27
34_T	43_A	0.592	0.27
58_L	441_G	0.591	0.27
634_K	673_E	0.590	0.27
52_A	74_A	0.590	0.27
253_A	260_N	0.590	0.27
533_D	537_A	0.589	0.27
218_K	582_H	0.588	0.27
257_F	275_G	0.588	0.27
521_E	592_L	0.587	0.27
350_L	585_I	0.586	0.27
488_N	548_N	0.586	0.27
257_F	273_W	0.586	0.27
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281_L	505_I	0.585	0.27
675_P	692_G	0.585	0.27
320_L	414_D	0.585	0.27
18_T	575_M	0.583	0.27
74_A	111_L	0.583	0.27
319_T	353_E	0.583	0.27
105_T	109_R	0.583	0.27
66_Q	332_K	0.583	0.27
63_V	453_L	0.583	0.27
498_E	549_V	0.581	0.27
570_G	656_G	0.580	0.27
244_A	247_N	0.580	0.27
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67_R	156_L	0.579	0.27
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245_P	660_D	0.578	0.26
167_L	471_Y	0.577	0.26
341_S	362_V	0.577	0.26
569_Q	659_L	0.576	0.26
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111_L	176_N	0.575	0.26
616_S	649_A	0.575	0.26
351_A	704_A	0.574	0.26
402_E	687_R	0.574	0.26
194_P	203_S	0.574	0.26
99_D	423_D	0.573	0.26
115_I	564_M	0.573	0.26
187_K	356_A	0.573	0.26
571_F	590_V	0.572	0.26
38_D	67_R	0.572	0.26
39_T	61_L	0.572	0.26
166_R	361_A	0.572	0.26
455_R	459_G	0.571	0.26
434_T	607_A	0.571	0.26
292_G	319_T	0.569	0.26
626_P	655_R	0.568	0.26
201_F	216_Q	0.568	0.26
33_K	38_D	0.568	0.26
236_K	241_A	0.568	0.26
30_D	99_D	0.567	0.26
218_K	613_V	0.567	0.26
400_A	415_A	0.567	0.26
263_E	280_E	0.567	0.26
75_N	386_F	0.566	0.26
187_K	204_A	0.566	0.26
351_A	489_K	0.566	0.26
444_F	684_S	0.565	0.26
157_K	401_V	0.564	0.26
580_L	583_E	0.563	0.26
94_T	251_L	0.561	0.25
410_T	413_I	0.561	0.25
65_Q	574_A	0.561	0.25
421_I	657_K	0.561	0.25
393_S	674_I	0.560	0.25
129_E	146_I	0.560	0.25
311_A	340_V	0.560	0.25
463_V	538_K	0.559	0.25
676_V	682_M	0.559	0.25
54_E	149_V	0.558	0.25
486_S	612_A	0.557	0.25
207_K	212_L	0.557	0.25
445_L	449_V	0.555	0.25
18_T	506_E	0.555	0.25
574_A	672_A	0.555	0.25
264_A	295_V	0.554	0.25
504_T	623_T	0.553	0.25
94_T	104_V	0.553	0.25
32_G	38_D	0.553	0.25
217_K	221_N	0.553	0.25
243_Q	439_L	0.552	0.25
262_I	274_K	0.552	0.25
536_E	553_L	0.552	0.25
320_L	325_E	0.551	0.25
184_P	508_I	0.551	0.25
195_Q	298_I	0.550	0.25
264_A	273_W	0.549	0.25
362_V	713_D	0.549	0.25
191_M	200_I	0.548	0.25
56_L	120_A	0.548	0.25
182_G	186_F	0.548	0.25
25_I	36_T	0.548	0.25
252_D	260_N	0.548	0.25
103_R	687_R	0.548	0.25
261_P	271_K	0.548	0.25
294_I	410_T	0.548	0.25
496_S	500_L	0.546	0.25
230_T	238_E	0.546	0.25
92_I	167_L	0.545	0.24
112_D	119_D	0.545	0.24
567_V	721_R	0.544	0.24
257_F	265_Q	0.544	0.24
130_T	133_R	0.543	0.24
469_V	683_A	0.543	0.24
426_L	439_L	0.543	0.24
510_N	567_V	0.543	0.24
549_V	704_A	0.543	0.24
666_N	695_F	0.542	0.24
552_D	561_R	0.542	0.24
498_E	553_L	0.542	0.24
488_N	605_G	0.541	0.24
38_D	72_K	0.541	0.24
206_D	362_V	0.540	0.24
95_P	99_D	0.540	0.24
110_V	399_I	0.540	0.24
490_H	600_D	0.539	0.24
162_E	401_V	0.539	0.24
637_I	651_I	0.539	0.24
526_L	549_V	0.538	0.24
483_E	489_K	0.538	0.24
606_P	612_A	0.538	0.24
277_L	286_L	0.538	0.24
320_L	430_I	0.538	0.24
63_V	676_V	0.537	0.24
579_P	616_S	0.537	0.24
420_S	458_Y	0.537	0.24
262_I	280_E	0.536	0.24
283_K	529_E	0.536	0.24
86_G	255_I	0.536	0.24
41_L	255_I	0.536	0.24
150_D	443_G	0.536	0.24
152_L	163_M	0.536	0.24
194_P	230_T	0.535	0.24
42_A	52_A	0.535	0.24
490_H	495_L	0.535	0.24
265_Q	295_V	0.535	0.24
320_L	324_E	0.534	0.24
500_L	549_V	0.534	0.24
162_E	681_D	0.534	0.24
526_L	540_I	0.533	0.24
264_A	272_I	0.533	0.24
366_D	421_I	0.533	0.24
533_D	538_K	0.533	0.24
474_S	651_I	0.533	0.24
85_K	677_S	0.532	0.24
402_E	436_E	0.532	0.24
193_N	464_T	0.532	0.24
556_G	598_H	0.532	0.24
29_V	101_S	0.532	0.24
404_K	463_V	0.532	0.24
122_E	151_R	0.531	0.24
220_I	255_I	0.531	0.24
579_P	698_T	0.530	0.24
682_M	696_W	0.529	0.24
526_L	537_A	0.528	0.24
322_S	339_Q	0.528	0.24
68_G	639_V	0.527	0.23
420_S	637_I	0.527	0.23
419_L	449_V	0.526	0.23
685_E	689_S	0.526	0.23
647_V	684_S	0.526	0.23
67_R	104_V	0.526	0.23
71_V	74_A	0.525	0.23
263_E	289_D	0.524	0.23
240_L	243_Q	0.523	0.23
219_G	231_A	0.522	0.23
117_V	147_N	0.521	0.23
165_N	169_D	0.521	0.23
552_D	715_V	0.520	0.23
251_L	259_P	0.520	0.23
87_Y	686_L	0.520	0.23
110_V	312_T	0.520	0.23
71_V	103_R	0.518	0.23
532_W	537_A	0.518	0.23
149_V	336_R	0.518	0.23
31_H	40_L	0.517	0.23
476_R	627_T	0.516	0.23
70_T	112_D	0.516	0.23
513_I	628_L	0.516	0.23
651_I	670_I	0.515	0.23
543_I	546_N	0.514	0.23
298_I	313_G	0.513	0.23
35_T	176_N	0.513	0.23
210_F	230_T	0.512	0.23
333_T	701_S	0.512	0.23
341_S	388_R	0.511	0.23
706_V	717_K	0.510	0.22
324_E	460_I	0.510	0.22
89_I	613_V	0.510	0.22
61_L	69_I	0.509	0.22
23_I	35_T	0.509	0.22
114_S	651_I	0.508	0.22
580_L	622_L	0.508	0.22
133_R	264_A	0.508	0.22
30_D	35_T	0.507	0.22
360_A	425_N	0.507	0.22
481_V	616_S	0.507	0.22
140_V	269_I	0.507	0.22
588_V	641_A	0.506	0.22
107_S	134_Q	0.506	0.22
82_A	386_F	0.506	0.22
631_P	707_P	0.506	0.22
41_L	389_L	0.505	0.22
104_V	124_I	0.505	0.22
563_V	567_V	0.504	0.22
474_S	690_T	0.503	0.22
52_A	345_G	0.503	0.22
109_R	472_R	0.502	0.22
234_K	374_A	0.502	0.22
254_A	257_F	0.502	0.22
158_L	162_E	0.501	0.22
118_V	320_L	0.501	0.22
354_I	464_T	0.501	0.22
69_I	77_S	0.500	0.22
166_R	173_Q	0.500	0.22
541_I	544_D	0.500	0.22
94_T	450_S	0.500	0.22
257_F	267_Y	0.500	0.22

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
4w224	1	0.9891	100	0.281	Contact Map
1n0uA	1	0.9606	100	0.29	Contact Map
4kiyV	1	0.8832	100	0.393	Contact Map
1darA	1	0.7894	100	0.398	Contact Map
2xexA	1	0.8682	100	0.401	Contact Map
4fn5A	1	0.856	100	0.407	Contact Map
2dy1A	1	0.8736	100	0.434	Contact Map
3j25A	1	0.8424	100	0.464	Contact Map
4zciA	1	0.625	100	0.586	Contact Map
2yweA	1	0.6467	100	0.587	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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