BGAL - SULSO - GREMLIN Contacts

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BGAL - Beta-galactosidase

UniProt:	P22498	Sequences: MYSFPNSFRFGWSQAGFQSEMGTPGSEDPNTDWYKWVHDPENMAAGLVSGDLPENGPGYWGNYKTFHDNAQKMGLKIARLNVEWSRIFPNPLPRPQNFDESKQDVTEVEINENELKRLDEYANKDALNHYREIFKDLKSRGLYFILNMYHWPLPLWLHDPIRVRRGDFTGPSGWLSTRTVYEFARFSAYIAWKFDDLVDEYSTMNEPNVVGGLGYVGVKSGFPPGYLSFELSRRAMYNIIQAHARAYDGIKSVSKKPVGIIYANSSFQPLTDKDMEAVEMAENDNRWWFFDAIIRGEITRGNEKIVRDDLKGRLDWIGVNYYTRTVVKRTEKGYVSLGGYGHGCERNSVSLAGLPTSDFGWEFFPEGLYDVLTKYWNRYHLYMYVTENGIADDADYQRPYYLVSHVYQVHRAINSGADVRGYLHWSLADNYEWASGFSMRFGLLKVDYNTKRLYWRPSALVYREIATNGAITDEIEHLNSVPPVKPLRH	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	489 (421)
Sequences:	6796 (4148)
Seq/√Len:	202.2

ECOLI - ASCB BGLB BGLA
BACSU - BGLA BGLC GMUD BGLH
SULSO - BGAL

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
26_S	125_D	4.300	1.00
135_K	197_L	3.673	1.00
409_V	419_V	3.196	1.00
131_R	197_L	3.176	1.00
71_Q	140_R	3.071	1.00
64_K	136_D	3.053	1.00
131_R	193_K	2.939	1.00
136_D	139_S	2.903	1.00
58_G	61_G	2.901	1.00
455_W	459_A	2.893	1.00
148_M	190_I	2.837	1.00
124_K	193_K	2.804	1.00
124_K	128_N	2.736	1.00
321_Y	405_H	2.717	1.00
128_N	132_E	2.708	1.00
88_F	189_Y	2.698	1.00
408_Q	411_R	2.677	1.00
271_T	274_D	2.598	1.00
25_G	61_G	2.562	1.00
188_A	192_W	2.550	1.00
68_D	140_R	2.500	1.00
12_W	75_L	2.473	1.00
402_L	424_H	2.391	1.00
181_Y	245_R	2.324	1.00
250_I	258_V	2.312	1.00
373_T	415_S	2.292	1.00
396_Y	457_P	2.285	1.00
369_Y	415_S	2.271	1.00
155_L	159_D	2.266	1.00
445_K	454_Y	2.237	1.00
143_Y	199_D	2.205	1.00
77_I	423_L	2.204	1.00
64_K	132_E	2.187	1.00
400_Y	404_S	2.170	1.00
38_H	51_D	2.155	1.00
248_D	252_S	2.137	1.00
59_Y	129_H	2.126	1.00
59_Y	78_A	2.062	1.00
67_H	133_I	2.049	1.00
463_R	467_T	1.964	1.00
82_V	146_L	1.942	1.00
67_H	140_R	1.935	1.00
134_F	194_F	1.919	1.00
138_K	197_L	1.900	1.00
369_Y	411_R	1.884	1.00
80_L	134_F	1.881	1.00
188_A	249_G	1.875	1.00
188_A	253_V	1.861	1.00
237_Y	298_I	1.859	1.00
300_R	304_K	1.858	1.00
184_A	249_G	1.858	1.00
125_D	128_N	1.855	1.00
35_K	159_D	1.836	1.00
250_I	256_K	1.833	1.00
23_T	30_N	1.816	1.00
131_R	135_K	1.794	1.00
136_D	140_R	1.792	1.00
31_T	85_S	1.763	1.00
35_K	155_L	1.753	1.00
14_Q	19_S	1.736	1.00
268_Q	370_D	1.721	1.00
30_N	35_K	1.703	1.00
257_P	382_Y	1.698	1.00
10_F	469_G	1.684	1.00
22_G	25_G	1.677	1.00
68_D	136_D	1.666	1.00
92_L	160_P	1.664	1.00
137_L	142_L	1.655	1.00
134_F	138_K	1.650	1.00
135_K	138_K	1.647	1.00
321_Y	367_G	1.630	1.00
67_H	136_D	1.628	1.00
184_A	245_R	1.622	1.00
384_Y	420_R	1.620	1.00
80_L	133_I	1.609	1.00
366_E	408_Q	1.606	1.00
179_T	182_E	1.598	1.00
143_Y	200_E	1.596	1.00
464_E	467_T	1.592	1.00
297_E	310_L	1.585	1.00
369_Y	373_T	1.581	1.00
77_I	145_I	1.579	1.00
374_K	378_R	1.574	1.00
131_R	194_F	1.567	1.00
372_L	417_A	1.566	1.00
9_R	77_I	1.558	1.00
63_Y	132_E	1.551	1.00
62_N	65_T	1.540	1.00
191_A	250_I	1.539	1.00
67_H	137_L	1.529	1.00
295_R	380_H	1.529	1.00
372_L	409_V	1.521	1.00
410_H	414_N	1.507	1.00
202_S	261_I	1.504	1.00
39_D	42_N	1.503	1.00
88_F	122_A	1.488	1.00
177_T	238_N	1.475	1.00
283_N	301_G	1.470	1.00
156_W	160_P	1.463	1.00
290_F	317_I	1.459	1.00
388_N	422_Y	1.452	1.00
202_S	316_W	1.452	1.00
226_Y	231_L	1.449	1.00
14_Q	78_A	1.449	1.00
424_H	443_L	1.444	1.00
175_L	231_L	1.438	1.00
368_L	409_V	1.433	1.00
127_L	189_Y	1.431	1.00
145_I	423_L	1.431	1.00
461_V	465_I	1.420	1.00
288_W	302_N	1.419	1.00
236_M	289_F	1.408	1.00
29_P	91_P	1.405	1.00
70_A	75_L	1.372	1.00
72_K	459_A	1.370	1.00
172_S	176_S	1.366	1.00
464_E	468_N	1.355	1.00
58_G	62_N	1.354	1.00
90_N	93_P	1.346	1.00
249_G	252_S	1.333	1.00
260_I	293_I	1.329	1.00
82_V	190_I	1.327	1.00
17_F	50_G	1.326	1.00
200_E	257_P	1.325	1.00
68_D	72_K	1.311	1.00
297_E	303_E	1.311	1.00
455_W	460_L	1.301	1.00
406_V	409_V	1.297	1.00
22_G	61_G	1.293	1.00
80_L	146_L	1.287	1.00
57_P	428_A	1.280	1.00
181_Y	184_A	1.274	1.00
199_D	255_K	1.274	1.00
131_R	196_D	1.274	1.00
82_V	87_I	1.269	1.00
204_M	242_A	1.264	1.00
404_S	407_Y	1.248	1.00
297_E	380_H	1.248	1.00
373_T	417_A	1.247	1.00
148_M	183_F	1.236	1.00
63_Y	136_D	1.234	1.00
228_S	231_L	1.232	1.00
358_D	393_D	1.231	1.00
5_P	413_I	1.228	1.00
92_L	182_E	1.227	1.00
460_L	463_R	1.224	1.00
376_W	418_D	1.210	1.00
210_V	239_I	1.203	1.00
247_Y	251_K	1.197	1.00
403_V	407_Y	1.187	1.00
192_W	253_V	1.182	1.00
204_M	239_I	1.178	1.00
70_A	444_L	1.170	1.00
174_W	179_T	1.168	1.00
187_S	246_A	1.168	1.00
127_L	193_K	1.167	1.00
59_Y	133_I	1.166	1.00
184_A	246_A	1.158	1.00
184_A	188_A	1.153	1.00
291_D	378_R	1.153	1.00
248_D	311_K	1.147	1.00
14_Q	80_L	1.146	1.00
410_H	471_I	1.145	1.00
399_P	461_V	1.138	1.00
448_Y	451_K	1.135	1.00
134_F	197_L	1.134	1.00
282_E	374_K	1.132	1.00
191_A	258_V	1.131	1.00
29_P	156_W	1.130	1.00
23_T	28_D	1.130	1.00
4_F	410_H	1.130	1.00
160_P	178_R	1.128	1.00
178_R	181_Y	1.124	1.00
269_P	278_V	1.123	1.00
22_G	26_S	1.122	1.00
264_N	371_V	1.117	1.00
269_P	275_M	1.112	1.00
158_H	226_Y	1.111	1.00
131_R	138_K	1.109	1.00
191_A	246_A	1.107	1.00
4_F	413_I	1.104	1.00
410_H	413_I	1.102	1.00
291_D	295_R	1.099	1.00
238_N	241_Q	1.098	1.00
90_N	156_W	1.095	1.00
250_I	254_S	1.091	1.00
462_Y	466_A	1.089	1.00
153_L	179_T	1.088	1.00
382_Y	418_D	1.088	1.00
127_L	131_R	1.086	1.00
187_S	249_G	1.083	1.00
294_I	381_L	1.083	1.00
180_V	245_R	1.078	1.00
249_G	253_V	1.077	1.00
12_W	70_A	1.075	1.00
245_R	249_G	1.072	1.00
270_L	328_K	1.071	1.00
72_K	455_W	1.070	1.00
178_R	182_E	1.067	1.00
366_E	370_D	1.066	1.00
158_H	215_Y	1.061	1.00
145_I	384_Y	1.060	1.00
382_Y	420_R	1.056	1.00
276_E	280_M	1.053	1.00
400_Y	403_V	1.049	1.00
122_A	189_Y	1.041	1.00
267_F	281_A	1.036	1.00
273_K	366_E	1.033	1.00
304_K	307_R	1.028	1.00
134_F	146_L	1.028	1.00
356_T	362_E	1.024	1.00
145_I	200_E	1.021	1.00
368_L	419_V	1.020	1.00
62_N	452_R	1.019	1.00
195_D	256_K	1.008	1.00
279_E	283_N	1.007	1.00
196_D	256_K	1.004	1.00
186_F	190_I	1.004	1.00
283_N	287_W	1.001	1.00
324_R	362_E	1.001	1.00
428_A	446_V	0.998	1.00
248_D	312_G	0.998	1.00
153_L	173_G	0.994	1.00
189_Y	193_K	0.993	1.00
275_M	278_V	0.993	1.00
274_D	329_R	0.987	1.00
447_D	452_R	0.985	1.00
282_E	286_R	0.982	1.00
9_R	145_I	0.978	1.00
281_A	327_V	0.974	1.00
368_L	385_V	0.969	0.99
273_K	329_R	0.966	0.99
259_G	318_G	0.965	0.99
440_R	448_Y	0.964	0.99
182_E	185_R	0.962	0.99
19_S	59_Y	0.958	0.99
7_S	420_R	0.956	0.99
190_I	194_F	0.954	0.99
29_P	89_P	0.953	0.99
393_D	438_S	0.951	0.99
282_E	287_W	0.944	0.99
297_E	300_R	0.944	0.99
87_I	189_Y	0.943	0.99
413_I	419_V	0.936	0.99
75_L	427_L	0.935	0.99
376_W	380_H	0.934	0.99
172_S	175_L	0.934	0.99
328_K	347_N	0.928	0.99
132_E	135_K	0.926	0.99
128_N	131_R	0.925	0.99
276_E	279_E	0.924	0.99
392_D	397_Q	0.923	0.99
156_W	159_D	0.922	0.99
28_D	85_S	0.922	0.99
305_I	309_D	0.917	0.99
357_S	390_I	0.915	0.99
324_R	364_F	0.914	0.99
191_A	256_K	0.913	0.99
94_R	185_R	0.913	0.99
267_F	278_V	0.912	0.99
246_A	249_G	0.911	0.99
355_P	404_S	0.909	0.99
438_S	450_T	0.907	0.99
390_I	397_Q	0.907	0.99
48_V	438_S	0.906	0.99
457_P	460_L	0.906	0.99
93_P	156_W	0.904	0.99
203_T	260_I	0.902	0.99
88_F	93_P	0.901	0.99
283_N	302_N	0.897	0.99
149_Y	153_L	0.894	0.99
32_D	158_H	0.894	0.99
304_K	308_D	0.893	0.99
247_Y	258_V	0.889	0.99
220_S	227_L	0.888	0.99
187_S	191_A	0.887	0.99
131_R	134_F	0.886	0.99
262_Y	290_F	0.886	0.99
391_A	439_M	0.885	0.99
259_G	316_W	0.883	0.99
27_E	123_N	0.883	0.99
245_R	248_D	0.883	0.99
127_L	190_I	0.881	0.99
180_V	241_Q	0.874	0.99
211_G	235_A	0.873	0.99
279_E	301_G	0.873	0.99
193_K	197_L	0.872	0.99
355_P	397_Q	0.871	0.99
202_S	318_G	0.869	0.99
76_K	469_G	0.867	0.99
155_L	158_H	0.864	0.99
369_Y	408_Q	0.863	0.99
63_Y	67_H	0.863	0.99
68_D	71_Q	0.856	0.99
70_A	142_L	0.855	0.99
359_F	439_M	0.853	0.99
407_Y	411_R	0.850	0.99
364_F	367_G	0.849	0.99
9_R	143_Y	0.846	0.99
272_D	275_M	0.845	0.99
460_L	464_E	0.839	0.99
203_T	243_H	0.838	0.99
129_H	133_I	0.836	0.99
65_T	68_D	0.835	0.99
243_H	247_Y	0.834	0.98
73_M	459_A	0.833	0.98
45_A	48_V	0.831	0.98
73_M	455_W	0.826	0.98
144_F	199_D	0.825	0.98
138_K	144_F	0.824	0.98
291_D	379_Y	0.821	0.98
204_M	210_V	0.819	0.98
66_F	453_L	0.814	0.98
44_A	48_V	0.814	0.98
91_P	156_W	0.809	0.98
3_S	6_N	0.809	0.98
396_Y	400_Y	0.808	0.98
92_L	156_W	0.807	0.98
270_L	274_D	0.806	0.98
323_T	362_E	0.803	0.98
319_V	383_M	0.801	0.98
230_E	234_R	0.801	0.98
287_W	378_R	0.799	0.98
412_A	417_A	0.797	0.98
50_G	53_P	0.797	0.98
300_R	303_E	0.795	0.98
209_V	263_A	0.793	0.98
264_N	319_V	0.793	0.98
175_L	226_Y	0.790	0.98
149_Y	152_P	0.790	0.98
368_L	408_Q	0.790	0.98
176_S	182_E	0.789	0.98
373_T	377_N	0.787	0.98
366_E	411_R	0.787	0.98
350_S	356_T	0.786	0.98
72_K	463_R	0.781	0.98
53_P	436_G	0.780	0.98
324_R	367_G	0.779	0.98
10_F	406_V	0.775	0.98
75_L	462_Y	0.775	0.98
13_S	423_L	0.774	0.98
138_K	143_Y	0.771	0.97
267_F	327_V	0.769	0.97
28_D	31_T	0.768	0.97
124_K	131_R	0.766	0.97
32_D	153_L	0.765	0.97
376_W	417_A	0.765	0.97
261_I	320_N	0.765	0.97
16_G	83_E	0.764	0.97
122_A	127_L	0.762	0.97
465_I	470_A	0.762	0.97
444_L	455_W	0.757	0.97
138_K	199_D	0.756	0.97
7_S	469_G	0.756	0.97
52_L	451_K	0.755	0.97
383_M	417_A	0.753	0.97
71_Q	141_G	0.751	0.97
19_S	57_P	0.750	0.97
83_E	152_P	0.747	0.97
183_F	187_S	0.746	0.97
372_L	419_V	0.744	0.97
189_Y	192_W	0.742	0.97
351_L	354_L	0.740	0.97
88_F	92_L	0.736	0.97
90_N	94_R	0.735	0.97
62_N	451_K	0.734	0.97
465_I	469_G	0.733	0.97
195_D	253_V	0.730	0.97
317_I	381_L	0.729	0.96
14_Q	428_A	0.729	0.96
191_A	253_V	0.729	0.96
236_M	288_W	0.727	0.96
276_E	366_E	0.726	0.96
5_P	418_D	0.725	0.96
146_L	198_V	0.724	0.96
240_I	310_L	0.724	0.96
87_I	190_I	0.722	0.96
160_P	182_E	0.722	0.96
363_F	392_D	0.721	0.96
294_I	314_L	0.721	0.96
137_L	140_R	0.720	0.96
302_N	306_V	0.717	0.96
266_S	370_D	0.716	0.96
294_I	317_I	0.716	0.96
3_S	410_H	0.715	0.96
373_T	376_W	0.714	0.96
310_L	313_R	0.714	0.96
177_T	241_Q	0.711	0.96
188_A	252_S	0.710	0.96
279_E	374_K	0.710	0.96
175_L	235_A	0.707	0.96
268_Q	324_R	0.707	0.96
69_N	444_L	0.706	0.96
359_F	391_A	0.704	0.96
240_I	293_I	0.704	0.96
357_S	361_W	0.703	0.96
192_W	249_G	0.701	0.96
372_L	412_A	0.699	0.96
198_V	201_Y	0.697	0.95
157_L	179_T	0.697	0.95
67_H	142_L	0.697	0.95
180_V	242_A	0.692	0.95
126_A	129_H	0.688	0.95
92_L	185_R	0.686	0.95
64_K	68_D	0.686	0.95
213_L	221_G	0.686	0.95
52_L	58_G	0.685	0.95
19_S	430_N	0.684	0.95
366_E	369_Y	0.684	0.95
406_V	424_H	0.682	0.95
24_P	30_N	0.681	0.95
320_N	386_T	0.680	0.95
296_G	311_K	0.679	0.95
242_A	246_A	0.678	0.95
427_L	444_L	0.676	0.95
73_M	443_L	0.674	0.95
358_D	392_D	0.674	0.95
432_E	441_F	0.673	0.95
443_L	462_Y	0.672	0.94
80_L	137_L	0.672	0.94
430_N	441_F	0.671	0.94
30_N	38_H	0.669	0.94
181_Y	185_R	0.667	0.94
70_A	427_L	0.666	0.94
135_K	196_D	0.665	0.94
264_N	375_Y	0.663	0.94
270_L	326_V	0.660	0.94
88_F	185_R	0.658	0.94
208_N	263_A	0.657	0.94
158_H	175_L	0.656	0.94
233_R	306_V	0.654	0.94
406_V	465_I	0.654	0.94
90_N	160_P	0.654	0.94
203_T	258_V	0.653	0.94
445_K	456_R	0.653	0.94
330_T	333_G	0.651	0.94
91_P	157_L	0.650	0.93
23_T	51_D	0.650	0.93
248_D	313_R	0.649	0.93
399_P	457_P	0.649	0.93
76_K	143_Y	0.649	0.93
11_G	423_L	0.647	0.93
82_V	134_F	0.646	0.93
23_T	83_E	0.646	0.93
275_M	279_E	0.645	0.93
190_I	201_Y	0.644	0.93
384_Y	423_L	0.641	0.93
409_V	413_I	0.641	0.93
180_V	184_A	0.640	0.93
321_Y	368_L	0.640	0.93
19_S	78_A	0.639	0.93
183_F	204_M	0.639	0.93
175_L	234_R	0.638	0.93
185_R	189_Y	0.637	0.93
411_R	415_S	0.636	0.93
384_Y	421_G	0.636	0.93
149_Y	210_V	0.636	0.93
319_V	375_Y	0.634	0.93
10_F	76_K	0.634	0.93
302_N	305_I	0.634	0.93
187_S	190_I	0.633	0.93
209_V	213_L	0.632	0.92
440_R	445_K	0.631	0.92
355_P	400_Y	0.629	0.92
15_A	19_S	0.626	0.92
247_Y	314_L	0.626	0.92
79_R	205_N	0.626	0.92
78_A	137_L	0.624	0.92
244_A	312_G	0.622	0.92
30_N	85_S	0.621	0.92
451_K	455_W	0.620	0.92
357_S	392_D	0.620	0.92
262_Y	289_F	0.620	0.92
69_N	428_A	0.620	0.92
304_K	411_R	0.620	0.92
148_M	187_S	0.619	0.92
47_L	50_G	0.616	0.92
40_P	43_M	0.616	0.92
403_V	461_V	0.616	0.92
226_Y	229_F	0.616	0.92
220_S	228_S	0.615	0.91
257_P	420_R	0.615	0.91
76_K	466_A	0.613	0.91
127_L	194_F	0.613	0.91
26_S	60_W	0.611	0.91
287_W	374_K	0.610	0.91
137_L	141_G	0.610	0.91
357_S	360_G	0.608	0.91
87_I	127_L	0.607	0.91
132_E	136_D	0.607	0.91
4_F	469_G	0.607	0.91
271_T	328_K	0.607	0.91
134_F	198_V	0.606	0.91
37_V	431_Y	0.604	0.91
465_I	468_N	0.604	0.91
430_N	433_W	0.603	0.91
375_Y	383_M	0.603	0.91
200_E	384_Y	0.602	0.91
22_G	60_W	0.599	0.90
223_P	228_S	0.599	0.90
445_K	452_R	0.599	0.90
449_N	452_R	0.598	0.90
214_G	224_P	0.596	0.90
356_T	360_G	0.595	0.90
328_K	349_V	0.594	0.90
234_R	238_N	0.594	0.90
341_G	344_C	0.594	0.90
135_K	139_S	0.593	0.90
30_N	155_L	0.593	0.90
264_N	286_R	0.593	0.90
4_F	10_F	0.589	0.90
431_Y	437_F	0.587	0.89
431_Y	448_Y	0.587	0.89
358_D	439_M	0.587	0.89
284_D	302_N	0.586	0.89
264_N	290_F	0.584	0.89
35_K	39_D	0.583	0.89
9_R	76_K	0.581	0.89
148_M	191_A	0.581	0.89
468_N	471_I	0.580	0.89
253_V	256_K	0.577	0.89
281_A	285_N	0.577	0.89
32_D	149_Y	0.576	0.89
46_G	438_S	0.575	0.89
259_G	384_Y	0.573	0.88
71_Q	139_S	0.573	0.88
195_D	254_S	0.572	0.88
318_G	386_T	0.571	0.88
383_M	419_V	0.571	0.88
370_D	373_T	0.570	0.88
90_N	182_E	0.569	0.88
14_Q	427_L	0.568	0.88
74_G	463_R	0.567	0.88
224_P	227_L	0.566	0.88
280_M	329_R	0.565	0.88
93_P	122_A	0.565	0.88
248_D	251_K	0.564	0.88
138_K	141_G	0.564	0.88
277_A	281_A	0.564	0.88
402_L	406_V	0.563	0.87
322_Y	387_E	0.563	0.87
145_I	202_S	0.562	0.87
265_S	325_T	0.561	0.87
243_H	293_I	0.560	0.87
266_S	282_E	0.560	0.87
36_W	223_P	0.559	0.87
22_G	28_D	0.559	0.87
277_A	280_M	0.558	0.87
174_W	204_M	0.558	0.87
399_P	403_V	0.557	0.87
157_L	182_E	0.556	0.87
199_D	257_P	0.555	0.87
7_S	413_I	0.554	0.87
444_L	459_A	0.553	0.87
9_R	200_E	0.553	0.87
268_Q	364_F	0.551	0.86
290_F	375_Y	0.551	0.86
156_W	182_E	0.550	0.86
215_Y	223_P	0.549	0.86
396_Y	399_P	0.549	0.86
36_W	225_G	0.549	0.86
215_Y	224_P	0.548	0.86
283_N	374_K	0.548	0.86
7_S	76_K	0.548	0.86
386_T	420_R	0.547	0.86
367_G	405_H	0.547	0.86
145_I	420_R	0.547	0.86
358_D	391_A	0.543	0.86
70_A	78_A	0.543	0.86
426_S	430_N	0.543	0.86
12_W	426_S	0.542	0.85
244_A	313_R	0.540	0.85
59_Y	70_A	0.539	0.85
269_P	274_D	0.538	0.85
359_F	435_S	0.537	0.85
411_R	414_N	0.537	0.85
346_R	349_V	0.537	0.85
29_P	88_F	0.536	0.85
147_N	261_I	0.536	0.85
64_K	67_H	0.535	0.85
349_V	353_G	0.534	0.85
215_Y	235_A	0.534	0.85
28_D	152_P	0.534	0.85
288_W	306_V	0.533	0.84
191_A	249_G	0.533	0.84
350_S	354_L	0.533	0.84
17_F	37_V	0.533	0.84
3_S	471_I	0.533	0.84
153_L	158_H	0.533	0.84
72_K	460_L	0.531	0.84
23_T	38_H	0.530	0.84
177_T	180_V	0.530	0.84
395_D	458_S	0.528	0.84
69_N	72_K	0.526	0.84
221_G	435_S	0.526	0.84
59_Y	67_H	0.526	0.84
425_W	430_N	0.525	0.84
390_I	394_A	0.524	0.83
19_S	129_H	0.523	0.83
261_I	386_T	0.522	0.83
221_G	224_P	0.521	0.83
274_D	328_K	0.521	0.83
75_L	142_L	0.519	0.83
134_F	144_F	0.518	0.83
287_W	291_D	0.517	0.83
233_R	309_D	0.515	0.82
407_Y	410_H	0.515	0.82
33_W	36_W	0.514	0.82
14_Q	430_N	0.513	0.82
354_L	362_E	0.513	0.82
261_I	316_W	0.512	0.82
14_Q	59_Y	0.512	0.82
17_F	151_W	0.511	0.82
278_V	327_V	0.511	0.82
271_T	353_G	0.511	0.82
266_S	371_V	0.510	0.82
262_Y	293_I	0.510	0.82
93_P	185_R	0.509	0.82
462_Y	465_I	0.509	0.82
77_I	384_Y	0.508	0.82
291_D	297_E	0.506	0.81
192_W	195_D	0.505	0.81
133_I	137_L	0.504	0.81
290_F	294_I	0.504	0.81
138_K	196_D	0.504	0.81
446_V	454_Y	0.503	0.81
37_V	50_G	0.502	0.81
203_T	246_A	0.502	0.81
184_A	248_D	0.501	0.81
277_A	327_V	0.501	0.81
376_W	383_M	0.500	0.81
251_K	257_P	0.500	0.81

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1uwiA	4	1	100	0.162	Contact Map
2jf7A	5	0.8609	100	0.185	Contact Map
1v02A	2	0.8732	100	0.185	Contact Map
1v08A	2	0.8712	100	0.185	Contact Map
3ptmA	1	0.8712	100	0.187	Contact Map
2dgaA	5	0.8773	100	0.19	Contact Map
1cbgA	2	0.8712	100	0.191	Contact Map
3wq5A	1	0.8712	100	0.192	Contact Map
3w53A	1	0.8712	100	0.195	Contact Map
1qvbA	3	0.9775	100	0.196	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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