SYS - SULSO - GREMLIN Contacts

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SYS - Serine--tRNA ligase

UniProt:	O33780	Sequences: MSWSILELLRKNPEDLKNNLKRRAIDVSLVDKAVELDKKWRQVLQEVEKLRHQHNVLSSQISKLSGEERKKKIEESKNLLKILEEKEKELEEIENERDRLLSSLPNLVADDVPNGPDDSYNVPIKFWGKFKVYEGDVQEFLKQIKDAKVNYEVIKWKPKGHAEMLEDVLHLGNTLKAAEIAGSRFYYLFNDIVWLDFSLLLFAIDYITQQGYTLVLPPYMLRGEVIQSVIDLDTFKDAIYKIENEDLYLIATAEHPIAAMFFKEEIEKDKLPLKFAGISPAFRKEASAANKDLKGIFRVHQFHKVEQFIFSTPEDSWKYHSELITNAESIFQQLELPYRIVNIASGDLGACAAKKFDLEVWMPAQAKFREMVSCSNCTDWQAFRMKIRYVDRKNNRRGYVHTLNSTAIASTRTITAILENYQREDGVVEVPKVLRKYLEAFPKAPKDYIYPLKNKII	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_01
Length:	457 (417)
Sequences:	4311 (2311)
Seq/√Len:	113.2

ECOLI - SYS
BACSU - SYS
HALSA - SYS
SULSO - SYS

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
423_R	429_E	4.448	1.00
261_F	275_F	4.021	1.00
206_Y	330_I	3.772	1.00
123_P	126_F	3.766	1.00
335_E	432_K	3.310	1.00
312_T	315_D	3.248	1.00
39_K	89_E	3.209	1.00
53_Q	75_E	3.132	1.00
317_W	378_T	3.110	1.00
46_E	82_I	3.001	1.00
159_K	167_D	2.810	1.00
315_D	318_K	2.716	1.00
202_F	333_Q	2.715	1.00
187_Y	260_M	2.707	1.00
435_R	442_P	2.651	1.00
391_D	398_G	2.595	1.00
429_E	435_R	2.590	1.00
353_A	378_T	2.587	1.00
170_H	189_F	2.581	1.00
102_S	227_Q	2.511	1.00
114_N	345_S	2.425	1.00
155_K	424_E	2.394	1.00
329_S	333_Q	2.394	1.00
32_K	96_E	2.386	1.00
22_R	114_N	2.365	1.00
125_K	328_E	2.359	1.00
206_Y	333_Q	2.354	1.00
274_K	322_E	2.339	1.00
164_M	428_V	2.321	1.00
125_K	340_I	2.317	1.00
17_K	31_D	2.301	1.00
432_K	435_R	2.270	1.00
418_L	428_V	2.241	1.00
205_D	437_Y	2.136	1.00
65_S	73_I	2.129	1.00
12_N	15_D	2.085	1.00
92_E	96_E	2.046	1.00
328_E	332_Q	2.041	1.00
319_Y	322_E	2.020	1.00
176_K	264_E	2.002	1.00
423_R	427_V	1.998	1.00
109_A	317_W	1.987	1.00
210_Q	329_S	1.959	1.00
180_I	187_Y	1.933	1.00
171_L	192_I	1.891	1.00
336_L	360_V	1.879	1.00
390_V	397_R	1.875	1.00
309_I	319_Y	1.874	1.00
223_G	248_Y	1.859	1.00
209_Q	333_Q	1.855	1.00
220_M	242_I	1.850	1.00
18_N	22_R	1.844	1.00
225_V	262_F	1.834	1.00
215_V	260_M	1.818	1.00
127_W	332_Q	1.815	1.00
337_P	420_N	1.809	1.00
133_Y	156_W	1.807	1.00
343_I	355_K	1.802	1.00
251_A	255_H	1.796	1.00
64_L	67_E	1.794	1.00
60_Q	63_K	1.759	1.00
111_D	354_K	1.757	1.00
52_H	56_V	1.731	1.00
129_K	132_V	1.730	1.00
35_E	39_K	1.703	1.00
342_N	354_K	1.701	1.00
109_A	378_T	1.700	1.00
18_N	21_K	1.699	1.00
219_Y	282_F	1.679	1.00
10_R	37_D	1.675	1.00
70_K	74_E	1.661	1.00
391_D	394_N	1.649	1.00
165_L	172_G	1.647	1.00
95_N	99_R	1.643	1.00
19_N	110_D	1.617	1.00
108_V	348_L	1.616	1.00
267_E	270_K	1.608	1.00
94_E	98_D	1.604	1.00
50_L	79_L	1.597	1.00
352_A	355_K	1.592	1.00
217_P	256_P	1.591	1.00
78_N	82_I	1.591	1.00
32_K	35_E	1.585	1.00
329_S	332_Q	1.581	1.00
179_E	264_E	1.549	1.00
268_K	312_T	1.545	1.00
56_V	60_Q	1.543	1.00
108_V	345_S	1.540	1.00
316_S	401_H	1.537	1.00
8_L	12_N	1.520	1.00
44_L	48_E	1.500	1.00
350_A	380_W	1.497	1.00
274_K	309_I	1.495	1.00
224_E	262_F	1.488	1.00
19_N	22_R	1.480	1.00
116_P	120_Y	1.480	1.00
186_Y	299_V	1.477	1.00
220_M	247_L	1.474	1.00
51_R	87_E	1.469	1.00
42_Q	46_E	1.458	1.00
245_E	284_K	1.458	1.00
82_I	85_E	1.456	1.00
160_G	163_E	1.453	1.00
196_D	303_H	1.444	1.00
408_I	413_T	1.426	1.00
38_K	42_Q	1.424	1.00
176_K	260_M	1.412	1.00
120_Y	344_A	1.405	1.00
53_Q	56_V	1.403	1.00
312_T	389_Y	1.398	1.00
46_E	49_K	1.396	1.00
70_K	73_I	1.396	1.00
166_E	175_L	1.395	1.00
177_A	186_Y	1.392	1.00
43_V	90_L	1.389	1.00
274_K	319_Y	1.372	1.00
223_G	246_D	1.364	1.00
257_I	277_G	1.361	1.00
310_F	400_V	1.353	1.00
8_L	15_D	1.340	1.00
69_R	73_I	1.338	1.00
22_R	345_S	1.338	1.00
13_P	34_V	1.336	1.00
268_K	392_R	1.335	1.00
189_F	213_T	1.332	1.00
88_K	92_E	1.330	1.00
57_L	76_S	1.330	1.00
181_A	247_L	1.306	1.00
43_V	93_I	1.303	0.99
261_F	310_F	1.286	0.99
311_S	319_Y	1.283	0.99
316_S	376_N	1.271	0.99
39_K	42_Q	1.266	0.99
74_E	78_N	1.259	0.99
321_S	356_F	1.256	0.99
223_G	236_K	1.255	0.99
37_D	41_R	1.251	0.99
335_E	421_Y	1.246	0.99
85_E	89_E	1.240	0.99
236_K	248_Y	1.239	0.99
365_Q	369_R	1.239	0.99
125_K	324_I	1.238	0.99
206_Y	209_Q	1.230	0.99
117_D	120_Y	1.227	0.99
14_E	18_N	1.222	0.99
317_W	353_A	1.215	0.99
325_T	332_Q	1.211	0.99
440_A	443_K	1.208	0.99
49_K	53_Q	1.208	0.99
421_Y	430_V	1.201	0.99
81_K	85_E	1.200	0.99
132_V	155_K	1.199	0.99
160_G	364_A	1.194	0.99
80_L	84_E	1.194	0.99
206_Y	329_S	1.190	0.99
222_R	225_V	1.190	0.99
126_F	130_F	1.185	0.99
40_W	44_L	1.182	0.99
88_K	91_E	1.181	0.99
130_F	337_P	1.175	0.99
19_N	108_V	1.173	0.99
332_Q	338_Y	1.164	0.99
340_I	358_L	1.157	0.99
77_K	80_L	1.155	0.99
257_I	377_C	1.154	0.99
332_Q	340_I	1.154	0.99
297_F	415_T	1.147	0.99
75_E	78_N	1.145	0.99
8_L	16_L	1.144	0.99
323_L	374_C	1.138	0.99
313_P	389_Y	1.136	0.99
309_I	322_E	1.135	0.99
374_C	405_S	1.128	0.99
200_L	278_I	1.128	0.99
43_V	86_K	1.126	0.99
99_R	103_S	1.123	0.98
111_D	317_W	1.121	0.98
387_I	400_V	1.119	0.98
323_L	377_C	1.118	0.98
133_Y	158_P	1.113	0.98
84_E	87_E	1.112	0.98
125_K	332_Q	1.112	0.98
206_Y	210_Q	1.106	0.98
89_E	92_E	1.106	0.98
60_Q	64_L	1.103	0.98
17_K	30_V	1.093	0.98
191_D	441_F	1.092	0.98
71_K	75_E	1.087	0.98
352_A	377_C	1.081	0.98
265_E	388_R	1.081	0.98
163_E	166_E	1.076	0.98
63_K	66_G	1.073	0.98
64_L	72_K	1.073	0.98
10_R	41_R	1.069	0.98
68_E	71_K	1.060	0.98
324_I	340_I	1.059	0.98
342_N	348_L	1.058	0.98
202_F	433_V	1.056	0.98
203_A	330_I	1.055	0.98
36_L	93_I	1.048	0.98
228_S	385_M	1.043	0.98
270_K	273_L	1.040	0.98
215_V	257_I	1.038	0.97
423_R	443_K	1.037	0.97
241_K	248_Y	1.033	0.97
121_N	344_A	1.026	0.97
91_E	95_N	1.023	0.97
386_K	399_Y	1.023	0.97
429_E	443_K	1.023	0.97
33_A	100_L	1.019	0.97
317_W	321_S	1.017	0.97
430_V	435_R	1.014	0.97
194_W	205_D	1.014	0.97
109_A	112_V	1.013	0.97
32_K	100_L	1.012	0.97
362_M	369_R	1.011	0.97
78_N	81_K	1.011	0.97
382_A	402_T	1.007	0.97
309_I	326_N	1.006	0.97
159_K	163_E	1.000	0.97
45_Q	49_K	0.996	0.97
427_V	443_K	0.995	0.97
84_E	88_K	0.994	0.97
7_E	11_K	0.993	0.97
9_L	12_N	0.993	0.97
333_Q	433_V	0.993	0.97
93_I	97_R	0.992	0.97
417_I	421_Y	0.988	0.97
389_Y	398_G	0.986	0.97
321_S	324_I	0.983	0.97
226_I	239_I	0.982	0.96
241_K	246_D	0.980	0.96
362_M	415_T	0.978	0.96
71_K	74_E	0.976	0.96
15_D	18_N	0.971	0.96
324_I	358_L	0.970	0.96
265_E	397_R	0.970	0.96
47_V	83_L	0.969	0.96
4_S	9_L	0.968	0.96
391_D	395_N	0.967	0.96
232_L	239_I	0.965	0.96
177_A	181_A	0.946	0.96
258_A	308_F	0.946	0.96
263_K	386_K	0.945	0.96
19_N	107_L	0.941	0.96
57_L	60_Q	0.940	0.95
15_D	19_N	0.938	0.95
58_S	76_S	0.937	0.95
216_L	303_H	0.937	0.95
35_E	38_K	0.933	0.95
33_A	104_L	0.927	0.95
318_K	322_E	0.926	0.95
133_Y	155_K	0.926	0.95
39_K	96_E	0.922	0.95
9_L	33_A	0.920	0.95
234_T	238_A	0.919	0.95
219_Y	280_P	0.917	0.95
117_D	346_G	0.917	0.95
268_K	391_D	0.914	0.95
50_L	82_I	0.912	0.95
39_K	93_I	0.911	0.95
430_V	438_L	0.905	0.94
59_S	62_S	0.903	0.94
65_S	69_R	0.902	0.94
156_W	424_E	0.898	0.94
274_K	326_N	0.897	0.94
268_K	271_L	0.893	0.94
210_Q	326_N	0.892	0.94
438_L	441_F	0.891	0.94
54_H	80_L	0.891	0.94
207_I	407_A	0.883	0.94
204_I	208_T	0.880	0.94
48_E	51_R	0.875	0.93
223_G	227_Q	0.874	0.93
87_E	91_E	0.871	0.93
4_S	16_L	0.870	0.93
325_T	328_E	0.868	0.93
123_P	339_R	0.864	0.93
112_V	342_N	0.864	0.93
128_G	131_K	0.863	0.93
96_E	99_R	0.861	0.93
4_S	8_L	0.860	0.93
328_E	338_Y	0.858	0.93
181_A	222_R	0.856	0.93
13_P	30_V	0.856	0.93
47_V	87_E	0.854	0.93
191_D	440_A	0.853	0.93
261_F	273_L	0.849	0.92
312_T	391_D	0.848	0.92
257_I	275_F	0.846	0.92
335_E	429_E	0.840	0.92
325_T	329_S	0.840	0.92
43_V	89_E	0.839	0.92
335_E	433_V	0.836	0.92
205_D	436_K	0.836	0.92
131_K	429_E	0.829	0.91
212_Y	309_I	0.828	0.91
242_I	247_L	0.824	0.91
191_D	438_L	0.817	0.91
200_L	410_S	0.815	0.91
265_E	390_V	0.813	0.91
100_L	103_S	0.812	0.91
330_I	408_I	0.810	0.90
23_R	349_G	0.809	0.90
76_S	79_L	0.805	0.90
376_N	401_H	0.805	0.90
261_F	266_I	0.801	0.90
209_Q	329_S	0.799	0.90
98_D	102_S	0.798	0.90
219_Y	303_H	0.797	0.90
59_S	63_K	0.793	0.90
58_S	62_S	0.793	0.90
320_H	356_F	0.792	0.89
24_A	116_P	0.791	0.89
181_A	225_V	0.790	0.89
194_W	208_T	0.790	0.89
36_L	96_E	0.786	0.89
280_P	303_H	0.781	0.89
219_Y	301_Q	0.777	0.89
196_D	216_L	0.776	0.88
364_A	415_T	0.773	0.88
124_I	342_N	0.773	0.88
48_E	90_L	0.773	0.88
76_S	80_L	0.770	0.88
421_Y	433_V	0.763	0.88
267_E	390_V	0.762	0.88
225_V	259_A	0.758	0.87
230_I	351_C	0.755	0.87
297_F	369_R	0.752	0.87
116_P	344_A	0.751	0.87
47_V	51_R	0.751	0.87
172_G	186_Y	0.749	0.87
435_R	441_F	0.746	0.86
240_Y	284_K	0.744	0.86
62_S	73_I	0.743	0.86
394_N	398_G	0.739	0.86
122_V	342_N	0.738	0.86
260_M	275_F	0.737	0.86
165_L	169_L	0.737	0.86
392_R	395_N	0.736	0.86
33_A	97_R	0.734	0.86
124_I	356_F	0.734	0.86
212_Y	326_N	0.733	0.86
73_I	77_K	0.727	0.85
170_H	190_N	0.727	0.85
160_G	415_T	0.726	0.85
46_E	86_K	0.723	0.85
364_A	367_K	0.721	0.85
164_M	422_Q	0.721	0.85
93_I	96_E	0.720	0.84
28_S	32_K	0.720	0.84
112_V	348_L	0.719	0.84
188_L	414_I	0.717	0.84
32_K	36_L	0.717	0.84
131_K	337_P	0.716	0.84
307_Q	323_L	0.716	0.84
44_L	94_E	0.716	0.84
43_V	46_E	0.715	0.84
48_E	52_H	0.715	0.84
47_V	90_L	0.713	0.84
219_Y	250_I	0.711	0.84
253_A	256_P	0.711	0.84
171_L	418_L	0.710	0.84
6_L	101_L	0.710	0.84
194_W	439_E	0.709	0.84
317_W	376_N	0.708	0.83
176_K	187_Y	0.705	0.83
182_G	247_L	0.705	0.83
189_F	215_V	0.704	0.83
198_S	438_L	0.702	0.83
343_I	352_A	0.702	0.83
207_I	276_A	0.698	0.83
15_D	110_D	0.698	0.83
430_V	443_K	0.698	0.83
38_K	41_R	0.698	0.83
57_L	72_K	0.695	0.82
53_Q	57_L	0.694	0.82
57_L	75_E	0.694	0.82
231_D	259_A	0.692	0.82
117_D	121_N	0.690	0.82
265_E	386_K	0.689	0.82
177_A	187_Y	0.689	0.82
118_D	341_V	0.689	0.82
171_L	191_D	0.688	0.82
232_L	236_K	0.684	0.81
324_I	374_C	0.684	0.81
188_L	303_H	0.683	0.81
253_A	276_A	0.683	0.81
62_S	77_K	0.682	0.81
184_R	371_M	0.681	0.81
95_N	98_D	0.680	0.81
96_E	100_L	0.680	0.81
31_D	35_E	0.677	0.81
258_A	377_C	0.676	0.81
21_K	27_V	0.675	0.80
241_K	244_N	0.675	0.80
429_E	442_P	0.675	0.80
181_A	242_I	0.675	0.80
184_R	292_D	0.670	0.80
266_I	270_K	0.670	0.80
51_R	83_L	0.670	0.80
74_E	77_K	0.669	0.80
36_L	97_R	0.669	0.80
171_L	189_F	0.668	0.80
72_K	75_E	0.665	0.79
261_F	387_I	0.665	0.79
14_E	17_K	0.664	0.79
202_F	206_Y	0.664	0.79
9_L	16_L	0.664	0.79
345_S	348_L	0.664	0.79
90_L	93_I	0.663	0.79
77_K	81_K	0.660	0.79
169_L	192_I	0.658	0.79
421_Y	432_K	0.657	0.79
172_G	188_L	0.654	0.78
60_Q	72_K	0.653	0.78
207_I	307_Q	0.651	0.78
65_S	70_K	0.650	0.78
30_V	33_A	0.650	0.78
64_L	68_E	0.650	0.78
181_A	221_L	0.650	0.78
158_P	364_A	0.649	0.78
62_S	69_R	0.648	0.78
313_P	398_G	0.647	0.78
165_L	418_L	0.646	0.78
190_N	213_T	0.646	0.78
47_V	86_K	0.644	0.77
39_K	43_V	0.644	0.77
273_L	276_A	0.643	0.77
81_K	84_E	0.643	0.77
54_H	83_L	0.642	0.77
221_L	256_P	0.640	0.77
89_E	93_I	0.635	0.76
239_I	251_A	0.635	0.76
40_W	97_R	0.634	0.76
155_K	158_P	0.633	0.76
239_I	255_H	0.632	0.76
40_W	94_E	0.631	0.76
264_E	270_K	0.629	0.76
215_V	275_F	0.628	0.76
317_W	320_H	0.627	0.75
204_I	276_A	0.627	0.75
229_V	308_F	0.626	0.75
21_K	26_D	0.626	0.75
266_I	400_V	0.626	0.75
348_L	355_K	0.625	0.75
40_W	93_I	0.625	0.75
310_F	387_I	0.625	0.75
240_Y	247_L	0.622	0.75
321_S	354_K	0.621	0.75
314_E	391_D	0.621	0.75
197_F	214_L	0.620	0.75
162_A	294_K	0.619	0.74
180_I	225_V	0.617	0.74
60_Q	68_E	0.617	0.74
236_K	241_K	0.616	0.74
201_L	278_I	0.616	0.74
212_Y	307_Q	0.616	0.74
296_I	415_T	0.616	0.74
229_V	258_A	0.615	0.74
278_I	303_H	0.614	0.74
308_F	377_C	0.613	0.74
430_V	441_F	0.613	0.74
130_F	133_Y	0.612	0.74
82_I	86_K	0.612	0.74
216_L	280_P	0.608	0.73
17_K	21_K	0.608	0.73
91_E	94_E	0.608	0.73
86_K	89_E	0.607	0.73
157_K	163_E	0.607	0.73
216_L	219_Y	0.604	0.73
180_I	260_M	0.603	0.73
9_L	34_V	0.602	0.72
191_D	194_W	0.600	0.72
391_D	396_R	0.599	0.72
124_I	324_I	0.598	0.72
85_E	88_K	0.596	0.72
220_M	249_L	0.596	0.72
37_D	101_L	0.596	0.72
174_T	296_I	0.595	0.72
181_A	220_M	0.595	0.72
59_S	66_G	0.594	0.71
184_R	369_R	0.592	0.71
164_M	167_D	0.592	0.71
292_D	369_R	0.591	0.71
417_I	430_V	0.590	0.71
50_L	83_L	0.590	0.71
133_Y	157_K	0.590	0.71
327_A	372_V	0.589	0.71
320_H	324_I	0.586	0.70
242_I	245_E	0.584	0.70
75_E	82_I	0.583	0.70
429_E	432_K	0.583	0.70
360_V	416_A	0.583	0.70
127_W	338_Y	0.582	0.70
259_A	262_F	0.582	0.70
116_P	119_S	0.579	0.70
371_M	413_T	0.579	0.70
186_Y	296_I	0.579	0.70
8_L	13_P	0.578	0.69
323_L	403_L	0.576	0.69
320_H	374_C	0.576	0.69
115_G	346_G	0.576	0.69
242_I	284_K	0.575	0.69
299_V	414_I	0.571	0.68
379_D	401_H	0.571	0.68
69_R	72_K	0.571	0.68
327_A	358_L	0.571	0.68
351_C	355_K	0.570	0.68
354_K	376_N	0.569	0.68
368_F	413_T	0.569	0.68
44_L	47_V	0.568	0.68
288_A	291_K	0.568	0.68
162_A	174_T	0.567	0.68
64_L	71_K	0.567	0.68
244_N	284_K	0.566	0.68
22_R	108_V	0.565	0.68
268_K	395_N	0.564	0.68
221_L	250_I	0.564	0.68
389_Y	400_V	0.563	0.67
98_D	227_Q	0.562	0.67
90_L	94_E	0.562	0.67
179_E	263_K	0.562	0.67
201_L	205_D	0.561	0.67
330_I	407_A	0.560	0.67
330_I	333_Q	0.560	0.67
222_R	247_L	0.560	0.67
109_A	353_A	0.560	0.67
269_D	392_R	0.559	0.67
273_L	310_F	0.559	0.67
159_K	164_M	0.559	0.67
322_E	326_N	0.558	0.67
196_D	410_S	0.558	0.67
284_K	288_A	0.557	0.67
364_A	369_R	0.556	0.66
351_C	377_C	0.555	0.66
369_R	411_T	0.555	0.66
391_D	397_R	0.554	0.66
23_R	108_V	0.554	0.66
8_L	11_K	0.553	0.66
266_I	273_L	0.552	0.66
436_K	439_E	0.551	0.66
261_F	264_E	0.551	0.66
54_H	58_S	0.550	0.66
196_D	411_T	0.549	0.65
239_I	248_Y	0.549	0.65
208_T	276_A	0.548	0.65
191_D	208_T	0.547	0.65
46_E	50_L	0.546	0.65
258_A	402_T	0.546	0.65
31_D	34_V	0.546	0.65
156_W	422_Q	0.545	0.65
158_P	422_Q	0.545	0.65
54_H	79_L	0.544	0.65
165_L	171_L	0.543	0.65
309_I	323_L	0.542	0.64
56_V	59_S	0.542	0.64
221_L	226_I	0.541	0.64
16_L	107_L	0.541	0.64
83_L	87_E	0.540	0.64
5_I	383_F	0.540	0.64
410_S	413_T	0.538	0.64
372_V	405_S	0.538	0.64
40_W	90_L	0.538	0.64
129_K	133_Y	0.537	0.64
188_L	216_L	0.537	0.64
61_I	76_S	0.534	0.63
17_K	27_V	0.534	0.63
68_E	73_I	0.534	0.63
45_Q	48_E	0.533	0.63
178_A	182_G	0.532	0.63
261_F	400_V	0.532	0.63
236_K	239_I	0.532	0.63
92_E	95_N	0.531	0.63
242_I	246_D	0.530	0.63
422_Q	426_G	0.530	0.63
62_S	65_S	0.529	0.63
253_A	277_G	0.528	0.62
207_I	210_Q	0.527	0.62
362_M	367_K	0.527	0.62
362_M	371_M	0.526	0.62
291_K	341_V	0.526	0.62
173_N	176_K	0.526	0.62
239_I	279_S	0.525	0.62
337_P	368_F	0.525	0.62
42_Q	45_Q	0.525	0.62
13_P	17_K	0.525	0.62
432_K	442_P	0.524	0.62
342_N	358_L	0.522	0.62
257_I	276_A	0.522	0.62
9_L	13_P	0.520	0.61
46_E	89_E	0.520	0.61
97_R	100_L	0.519	0.61
313_P	400_V	0.519	0.61
203_A	406_T	0.518	0.61
237_D	284_K	0.518	0.61
23_R	345_S	0.517	0.61
169_L	428_V	0.517	0.61
111_D	342_N	0.517	0.61
49_K	52_H	0.516	0.61
229_V	255_H	0.516	0.61
413_T	417_I	0.515	0.61
66_G	69_R	0.515	0.61
43_V	47_V	0.515	0.61
251_A	406_T	0.514	0.60
299_V	415_T	0.513	0.60
109_A	376_N	0.513	0.60
187_Y	217_P	0.511	0.60
430_V	440_A	0.511	0.60
27_V	30_V	0.510	0.60
236_K	243_E	0.509	0.60
57_L	69_R	0.507	0.59
121_N	346_G	0.507	0.59
196_D	278_I	0.506	0.59
394_N	397_R	0.505	0.59
204_I	214_L	0.505	0.59
389_Y	392_R	0.504	0.59
438_L	442_P	0.504	0.59
417_I	433_V	0.503	0.59
324_I	356_F	0.503	0.59
289_A	293_L	0.502	0.59
207_I	330_I	0.501	0.58
126_F	368_F	0.500	0.58
217_P	277_G	0.500	0.58
379_D	383_F	0.500	0.58
184_R	291_K	0.500	0.58

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1sesA	2	0.9168	100	0.274	Contact Map
2dq0A	2	0.9584	100	0.275	Contact Map
1wleA	2	0.9387	100	0.286	Contact Map
3lssA	2	0.9278	100	0.288	Contact Map
2dq3A	2	0.9212	100	0.29	Contact Map
3vbbA	2	0.9278	100	0.3	Contact Map
3qneA	2	0.9409	100	0.315	Contact Map
3errA	2	0.9103	100	0.397	Contact Map
2cjaA	2	0.8643	100	0.559	Contact Map
3w3sA	2	0.8534	100	0.619	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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