GREMLIN Database
ABC_tran_2 - Putative ATP-binding cassette
PFAM: PF16949 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 542 (530)
Sequences: 2744 (2259)
Seq/√Len: 98.1
META: 0.909

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
120_G130_Y4.8131.00
120_G129_F4.3761.00
385_L395_L3.9601.00
74_F264_G3.9231.00
74_F153_L3.8511.00
136_V220_A3.5791.00
435_T489_E3.4811.00
189_P192_L3.3851.00
188_R191_R3.3711.00
449_G452_A3.1421.00
25_F121_I3.1381.00
305_L309_R2.9371.00
361_F365_A2.8881.00
525_A529_P2.7401.00
93_F253_A2.7281.00
449_G533_G2.6431.00
442_G481_Y2.6021.00
101_L105_S2.5491.00
514_S518_A2.5461.00
188_R192_L2.5411.00
61_L64_S2.5001.00
150_L256_L2.4641.00
499_A503_G2.4421.00
90_R258_E2.4331.00
307_D403_G2.3981.00
189_P193_V2.3661.00
524_L528_L2.3511.00
445_G449_G2.3371.00
65_N145_A2.3061.00
515_L518_A2.2931.00
521_L525_A2.2701.00
481_Y522_S2.2691.00
216_P219_W2.2691.00
460_E464_Q2.2031.00
522_S525_A2.1541.00
513_L517_L2.1501.00
459_E462_P2.1431.00
120_G125_A2.1021.00
518_A522_S2.0991.00
511_L514_S2.0981.00
248_A251_V2.0971.00
139_P243_L2.0891.00
257_A261_Y2.0211.00
452_A533_G2.0091.00
13_L16_L2.0061.00
412_L437_L1.9821.00
447_A474_F1.9721.00
143_I249_L1.9721.00
148_G152_T1.9581.00
416_V433_L1.9371.00
511_L515_L1.9331.00
127_W131_L1.9031.00
382_F457_F1.9001.00
311_F318_W1.8381.00
177_A181_L1.8361.00
523_L527_L1.8331.00
11_L15_L1.8251.00
522_S526_T1.8131.00
528_L532_L1.8001.00
190_E193_V1.7961.00
242_L245_T1.7821.00
12_L15_L1.7771.00
518_A521_L1.7611.00
527_L531_R1.7521.00
507_S510_E1.7521.00
306_K385_L1.7381.00
150_L253_A1.7311.00
320_Q331_Y1.7271.00
472_L475_M1.7251.00
408_L437_L1.7151.00
203_F207_L1.6961.00
498_A502_R1.6951.00
125_A130_Y1.6801.00
294_R297_S1.6791.00
501_F505_L1.6771.00
236_L240_L1.6761.00
61_L65_N1.6651.00
189_P194_N1.6581.00
78_D81_L1.6521.00
317_Q320_Q1.6521.00
404_L441_F1.6471.00
439_L481_Y1.6471.00
467_T470_G1.6401.00
375_V396_L1.6111.00
377_L465_I1.6071.00
465_I468_S1.6051.00
408_L412_L1.6011.00
114_P118_A1.5931.00
118_A122_V1.5841.00
38_V41_L1.5601.00
136_V223_A1.5591.00
514_S517_L1.5571.00
510_E514_S1.5571.00
516_G519_L1.5551.00
498_A501_F1.5511.00
191_R194_N1.5511.00
502_R507_S1.5311.00
400_F445_G1.5131.00
64_S67_I1.5121.00
153_L257_A1.5081.00
369_R373_P1.5061.00
499_A502_R1.5001.00
237_F244_S1.4991.00
499_A504_R1.4981.00
488_L492_P1.4871.00
331_Y355_N1.4871.00
518_A526_T1.4871.00
503_G508_G1.4861.00
498_A503_G1.4851.00
484_L521_L1.4821.00
504_R507_S1.4731.00
18_L22_A1.4641.00
518_A525_A1.4581.00
163_R166_D1.4511.00
176_A180_V1.4481.00
295_P298_P1.4411.00
9_R16_L1.4381.00
180_V183_F1.4381.00
515_L519_L1.4381.00
378_E399_K1.4321.00
256_L260_L1.4281.00
501_F504_R1.4231.00
96_K99_E1.4201.00
70_L75_L1.4161.00
241_L245_T1.4071.00
391_S394_R1.4041.00
445_G448_V1.4021.00
501_F507_S1.4021.00
14_G18_L1.4000.99
376_S465_I1.3970.99
15_L19_L1.3960.99
240_L243_L1.3930.99
179_L183_F1.3890.99
505_L520_L1.3800.99
503_G507_S1.3800.99
44_L48_K1.3690.99
248_A252_L1.3650.99
459_E464_Q1.3650.99
508_G515_L1.3640.99
500_R503_G1.3620.99
369_R372_F1.3590.99
507_S516_G1.3560.99
307_D313_R1.3490.99
23_G28_F1.3470.99
153_L261_Y1.3440.99
320_Q355_N1.3410.99
445_G451_G1.3390.99
292_R295_P1.3380.99
510_E513_L1.3300.99
501_F512_A1.3210.99
426_P430_L1.3200.99
517_L521_L1.3190.99
168_L171_L1.3120.99
506_L509_A1.3100.99
505_L509_A1.3100.99
332_L421_L1.3080.99
507_S514_S1.3050.99
509_A515_L1.3000.99
400_F448_V1.2980.99
485_V489_E1.2940.99
500_R504_R1.2930.99
510_E516_G1.2920.99
187_R192_L1.2910.99
193_V197_F1.2890.99
383_W387_S1.2870.99
322_L371_V1.2840.99
468_S471_G1.2770.99
38_V43_D1.2670.99
532_L536_R1.2650.99
161_A166_D1.2600.99
101_L145_A1.2600.99
498_A506_L1.2560.99
157_R264_G1.2530.99
508_G512_A1.2520.99
502_R510_E1.2470.99
303_L398_S1.2460.99
509_A512_A1.2420.99
153_L256_L1.2400.99
169_L172_G1.2390.99
500_R510_E1.2390.99
517_L522_S1.2340.99
141_L144_P1.2330.99
506_L510_E1.2270.99
504_R510_E1.2230.99
132_L227_A1.2200.99
42_G45_L1.2130.99
371_V403_G1.2090.99
371_V444_V1.2070.98
307_D398_S1.2060.98
504_R520_L1.2060.98
505_L511_L1.2050.98
512_A515_L1.2050.98
181_L185_L1.2030.98
368_A371_V1.2010.98
74_F156_V1.1970.98
505_L510_E1.1970.98
25_F29_Y1.1970.98
111_F115_V1.1920.98
501_F515_L1.1910.98
404_L408_L1.1880.98
450_L477_L1.1880.98
193_V196_E1.1850.98
514_S525_A1.1840.98
516_G520_L1.1830.98
116_L133_A1.1810.98
88_S91_R1.1780.98
503_G523_L1.1760.98
306_K399_K1.1750.98
194_N197_F1.1680.98
503_G511_L1.1650.98
38_V54_F1.1630.98
397_W530_L1.1630.98
505_L523_L1.1610.98
237_F240_L1.1520.98
509_A514_S1.1510.98
499_A505_L1.1500.98
275_R278_K1.1480.98
501_F511_L1.1460.98
507_S512_A1.1420.98
504_R519_L1.1410.98
468_S475_M1.1400.98
192_L195_P1.1260.98
498_A504_R1.1240.98
29_Y121_I1.1220.98
375_V452_A1.1200.98
513_L516_G1.1180.97
13_L18_L1.1140.97
504_R508_G1.1140.97
502_R513_L1.1140.97
303_L307_D1.1130.97
159_F162_R1.1100.97
30_R34_Y1.1090.97
31_V34_Y1.1090.97
503_G515_L1.1070.97
93_F257_A1.1060.97
501_F508_G1.1050.97
512_A517_L1.1050.97
95_A99_E1.1040.97
10_L15_L1.1040.97
38_V42_G1.1030.97
181_L184_R1.1010.97
504_R515_L1.0950.97
299_P302_A1.0930.97
506_L513_L1.0930.97
267_K270_E1.0910.97
244_S248_A1.0880.97
528_L531_R1.0870.97
66_I151_L1.0870.97
499_A507_S1.0850.97
89_P262_F1.0830.97
74_F257_A1.0830.97
508_G516_G1.0820.97
105_S108_V1.0820.97
314_D317_Q1.0800.97
23_G26_G1.0800.97
188_R194_N1.0790.97
456_N459_E1.0760.97
64_S369_R1.0750.97
533_G536_R1.0750.97
140_F220_A1.0700.97
521_L526_T1.0680.97
513_L521_L1.0640.97
509_A523_L1.0610.97
505_L517_L1.0590.97
42_G47_E1.0590.97
369_R451_G1.0590.97
65_N68_T1.0580.97
64_S355_N1.0570.96
312_F315_P1.0570.96
415_I436_I1.0570.96
509_A513_L1.0560.96
509_A531_R1.0540.96
503_G506_L1.0510.96
504_R511_L1.0510.96
498_A516_G1.0450.96
504_R513_L1.0450.96
65_N69_A1.0330.96
277_F280_K1.0330.96
416_V420_L1.0320.96
359_A362_V1.0300.96
187_R190_E1.0260.96
531_R534_L1.0210.96
82_L96_K1.0200.96
81_L84_S1.0180.96
506_L514_S1.0150.96
504_R521_L1.0130.96
380_R458_K1.0120.95
246_A250_V1.0110.95
97_F149_S1.0090.95
168_L172_G1.0090.95
507_S515_L1.0050.95
527_L530_L1.0000.95
521_L524_L0.9990.95
144_P455_P0.9980.95
105_S141_L0.9880.95
471_G475_M0.9850.95
499_A511_L0.9770.95
442_G445_G0.9770.95
511_L517_L0.9740.94
499_A508_G0.9730.94
507_S511_L0.9680.94
459_E465_I0.9670.94
510_E517_L0.9660.94
499_A510_E0.9640.94
77_R80_E0.9640.94
188_R193_V0.9630.94
125_A129_F0.9620.94
306_K381_A0.9590.94
162_R165_R0.9580.94
514_S522_S0.9580.94
268_A271_S0.9540.94
506_L517_L0.9530.94
498_A507_S0.9510.94
500_R507_S0.9500.94
462_P466_V0.9500.94
57_F65_N0.9470.94
57_F64_S0.9470.94
470_G475_M0.9460.94
502_R512_A0.9440.93
508_G511_L0.9410.93
250_V254_A0.9410.93
511_L522_S0.9400.93
506_L515_L0.9400.93
500_R505_L0.9390.93
238_Y242_L0.9360.93
9_R15_L0.9300.93
335_F358_L0.9270.93
154_L260_L0.9250.93
499_A506_L0.9240.93
373_P451_G0.9230.93
508_G514_S0.9200.93
508_G517_L0.9200.93
376_S379_G0.9180.93
309_R313_R0.9170.92
92_I257_A0.9170.92
182_L186_L0.9160.92
467_T471_G0.9100.92
531_R535_R0.9060.92
396_L448_V0.9060.92
502_R506_L0.9060.92
239_L505_L0.9060.92
515_L526_T0.9020.92
222_E238_Y0.9010.92
527_L532_L0.8990.92
508_G524_L0.8970.92
506_L524_L0.8950.92
517_L526_T0.8950.92
318_W386_R0.8940.92
200_L476_V0.8940.92
129_F133_A0.8900.91
64_S114_P0.8900.91
505_L514_S0.8870.91
504_R509_A0.8870.91
534_L538_E0.8860.91
276_R279_R0.8840.91
325_F328_L0.8810.91
466_V470_G0.8800.91
499_A513_L0.8780.91
13_L19_L0.8770.91
156_V267_K0.8740.91
248_A280_K0.8720.90
9_R12_L0.8720.90
500_R520_L0.8710.90
259_R263_K0.8710.90
144_P203_F0.8700.90
500_R511_L0.8700.90
514_S519_L0.8700.90
436_I440_T0.8680.90
502_R505_L0.8660.90
500_R506_L0.8660.90
471_G474_F0.8650.90
495_L510_E0.8650.90
73_L97_F0.8620.90
19_L22_A0.8610.90
85_L388_S0.8590.90
10_L18_L0.8580.90
94_L250_V0.8570.90
520_L524_L0.8550.90
439_L443_L0.8500.89
510_E515_L0.8470.89
69_A152_T0.8430.89
187_R191_R0.8420.89
24_L28_F0.8400.89
515_L521_L0.8390.89
532_L535_R0.8390.89
181_L256_L0.8360.89
502_R508_G0.8340.88
509_A516_G0.8330.88
502_R523_L0.8330.88
22_A25_F0.8310.88
469_F473_L0.8300.88
240_L244_S0.8280.88
230_G235_A0.8280.88
373_P377_L0.8260.88
255_W258_E0.8240.88
121_I129_F0.8210.88
503_G513_L0.8200.88
504_R527_L0.8180.87
32_L35_L0.8180.87
503_G510_E0.8170.87
65_N104_S0.8170.87
508_G513_L0.8130.87
99_E373_P0.8100.87
367_A447_A0.8100.87
179_L182_L0.8090.87
74_F157_R0.8080.87
436_I439_L0.8070.87
501_F513_L0.8060.87
481_Y489_E0.8060.87
49_L53_L0.8060.87
241_L244_S0.8060.87
190_E194_N0.8030.86
506_L511_L0.8020.86
393_R397_W0.8010.86
304_L398_S0.7990.86
353_F356_L0.7990.86
176_A182_L0.7990.86
153_L260_L0.7970.86
354_L357_G0.7960.86
106_W369_R0.7960.86
75_L78_D0.7950.86
318_W334_N0.7950.86
309_R312_F0.7930.86
215_L219_W0.7910.86
140_F144_P0.7910.86
505_L508_G0.7890.85
177_A182_L0.7890.85
131_L146_A0.7870.85
189_P195_P0.7860.85
216_P221_A0.7840.85
498_A513_L0.7830.85
112_G368_A0.7830.85
501_F518_A0.7820.85
388_S395_L0.7790.85
529_P532_L0.7780.85
302_A371_V0.7780.85
510_E526_T0.7780.85
514_S521_L0.7780.85
468_S472_L0.7750.84
146_A149_S0.7730.84
15_L18_L0.7720.84
518_A523_L0.7710.84
275_R279_R0.7710.84
502_R516_G0.7700.84
313_R451_G0.7680.84
320_Q369_R0.7680.84
278_K285_R0.7670.84
184_R189_P0.7660.84
47_E51_S0.7640.84
504_R514_S0.7630.84
451_G455_P0.7620.83
329_V417_L0.7610.83
276_R536_R0.7590.83
219_W318_W0.7580.83
177_A184_R0.7570.83
303_L385_L0.7550.83
393_R538_E0.7550.83
17_G21_W0.7530.83
498_A512_A0.7510.83
504_R517_L0.7470.82
101_L141_L0.7470.82
117_L121_I0.7450.82
347_L387_S0.7440.82
365_A407_L0.7420.82
120_G264_G0.7410.82
85_L89_P0.7410.82
299_P394_R0.7380.81
72_T76_S0.7370.81
158_V165_R0.7360.81
13_L20_F0.7320.81
487_V502_R0.7300.81
152_T156_V0.7300.81
80_E84_S0.7300.81
524_L527_L0.7290.81
373_P470_G0.7270.80
220_A224_L0.7270.80
505_L519_L0.7260.80
508_G518_A0.7220.80
498_A514_S0.7220.80
501_F516_G0.7210.80
104_S372_F0.7200.80
449_G454_Y0.7190.80
104_S373_P0.7190.80
260_L438_L0.7180.80
302_A306_K0.7170.80
39_E248_A0.7170.80
231_D234_E0.7160.79
57_F61_L0.7150.79
128_L131_L0.7090.79
42_G48_K0.7080.79
513_L526_T0.7080.79
345_P348_Q0.7060.79
160_P166_D0.7060.79
10_L14_G0.7060.79
83_L92_I0.7040.78
443_L478_S0.7040.78
133_A224_L0.7040.78
153_L264_G0.7030.78
456_N464_Q0.7010.78
160_P163_R0.7010.78
205_A208_R0.7010.78
355_N372_F0.6980.78
509_A517_L0.6980.78
428_M431_L0.6970.78
309_R317_Q0.6950.77
306_K318_W0.6940.77
507_S513_L0.6920.77
466_V475_M0.6920.77
519_L523_L0.6900.77
495_L500_R0.6890.77
28_F32_L0.6890.77
88_S226_A0.6880.77
218_T222_E0.6860.77
184_R187_R0.6850.76
83_L261_Y0.6840.76
82_L87_V0.6830.76
442_G449_G0.6820.76
238_Y241_L0.6820.76
454_Y470_G0.6820.76
49_L56_T0.6820.76
465_I470_G0.6800.76
331_Y334_N0.6800.76
219_W383_W0.6800.76
242_L248_A0.6780.76
116_L224_L0.6770.76
266_S270_E0.6770.76
64_S471_G0.6760.75
459_E467_T0.6750.75
511_L518_A0.6740.75
507_S518_A0.6740.75
278_K281_R0.6730.75
92_I96_K0.6720.75
79_L261_Y0.6710.75
16_L20_F0.6700.75
160_P314_D0.6690.75
97_F144_P0.6690.75
367_A443_L0.6690.75
54_F314_D0.6680.75
469_F475_M0.6670.75
320_Q463_A0.6670.75
500_R512_A0.6660.74
138_L290_L0.6640.74
104_S319_S0.6640.74
292_R297_S0.6610.74
516_G527_L0.6590.74
223_A244_S0.6580.74
503_G509_A0.6570.73
39_E46_A0.6540.73
306_K314_D0.6530.73
496_Y499_A0.6530.73
505_L524_L0.6510.73
106_W355_N0.6500.73
520_L528_L0.6500.73
448_V452_A0.6490.72
68_T72_T0.6490.72
489_E494_Y0.6480.72
521_L528_L0.6470.72
511_L520_L0.6460.72
373_P376_S0.6450.72
449_G529_P0.6450.72
29_Y33_R0.6450.72
525_A528_L0.6440.72
498_A510_E0.6430.72
22_A29_Y0.6420.72
333_Y337_V0.6410.72
504_R512_A0.6410.72
517_L532_L0.6400.71
464_Q469_F0.6390.71
457_F461_N0.6380.71
293_L298_P0.6360.71
358_L362_V0.6350.71
434_V512_A0.6340.71
466_V471_G0.6340.71
461_N466_V0.6330.71
304_L402_F0.6330.71
510_E518_A0.6320.70
159_F169_L0.6300.70
514_S523_L0.6290.70
112_G133_A0.6290.70
57_F67_I0.6280.70
507_S524_L0.6280.70
511_L516_G0.6270.70
106_W331_Y0.6260.70
512_A526_T0.6250.70
508_G519_L0.6240.70
412_L433_L0.6240.70
512_A516_G0.6240.70
326_A334_N0.6240.70
20_F35_L0.6230.69
467_T472_L0.6230.69
404_L437_L0.6220.69
487_V516_G0.6210.69
352_S356_L0.6200.69
365_A411_A0.6200.69
512_A525_A0.6200.69
507_S527_L0.6190.69
264_G314_D0.6190.69
62_L65_N0.6180.69
529_P534_L0.6170.69
148_G369_R0.6160.69
227_A235_A0.6160.69
58_F64_S0.6110.68
513_L520_L0.6110.68
76_S96_K0.6100.68
375_V410_L0.6070.67
146_A253_A0.6070.67
69_A100_T0.6070.67
453_L456_N0.6070.67
181_L205_A0.6050.67
525_A536_R0.6050.67
313_R320_Q0.6040.67
334_N369_R0.6040.67
503_G520_L0.6040.67
487_V513_L0.6020.67
443_L449_G0.6020.67
114_P383_W0.6020.67
41_L204_L0.6010.67
48_K51_S0.6010.67
503_G535_R0.5990.66
502_R511_L0.5980.66
314_D319_S0.5970.66
320_Q324_L0.5960.66
64_S331_Y0.5960.66
159_F165_R0.5960.66
439_L485_V0.5960.66
509_A520_L0.5950.66
292_R524_L0.5950.66
64_S334_N0.5950.66
237_F241_L0.5940.66
507_S517_L0.5930.66
301_R305_L0.5930.66
10_L16_L0.5930.66
262_F265_W0.5920.66
500_R525_A0.5920.66
316_T376_S0.5920.66
518_A524_L0.5920.66
307_D395_L0.5910.65
528_L535_R0.5900.65
51_S54_F0.5890.65
56_T150_L0.5880.65
108_V334_N0.5860.65
442_G446_L0.5860.65
174_L391_S0.5860.65
470_G474_F0.5850.65
498_A505_L0.5840.64
501_F534_L0.5840.64
55_L217_S0.5840.64
525_A532_L0.5830.64
105_S470_G0.5830.64
495_L498_A0.5810.64
40_E44_L0.5810.64
274_A279_R0.5810.64
501_F506_L0.5800.64
40_E43_D0.5780.64
375_V395_L0.5770.64
516_G522_S0.5770.64
513_L518_A0.5760.63
154_L299_P0.5760.63
310_L313_R0.5760.63
318_W422_L0.5750.63
146_A249_L0.5750.63
500_R528_L0.5740.63
524_L535_R0.5730.63
512_A518_A0.5720.63
307_D315_P0.5700.63
373_P465_I0.5690.62
530_L534_L0.5690.62
306_K378_E0.5680.62
189_P197_F0.5680.62
477_L480_L0.5680.62
512_A520_L0.5680.62
284_R287_D0.5670.62
533_G537_L0.5660.62
265_W303_L0.5660.62
526_T529_P0.5660.62
437_L445_G0.5640.62
509_A521_L0.5640.62
523_L526_T0.5640.62
58_F217_S0.5630.62
58_F144_P0.5630.62
332_L417_L0.5620.62
263_K267_K0.5620.62
187_R193_V0.5620.62
121_I125_A0.5590.61
27_L31_V0.5590.61
484_L517_L0.5590.61
160_P164_A0.5590.61
140_F217_S0.5580.61
300_V401_W0.5580.61
42_G46_A0.5570.61
524_L529_P0.5560.61
512_A521_L0.5550.61
515_L522_S0.5550.61
511_L528_L0.5550.61
257_A264_G0.5550.61
9_R13_L0.5540.60
501_F510_E0.5530.60
285_R288_R0.5530.60
321_L361_F0.5530.60
69_A148_G0.5510.60
461_N465_I0.5510.60
500_R514_S0.5490.60
487_V538_E0.5490.60
107_M324_L0.5490.60
151_L514_S0.5480.60
392_L395_L0.5480.60
463_A467_T0.5480.60
515_L525_A0.5480.60
73_L92_I0.5480.60
451_G454_Y0.5470.59
515_L528_L0.5460.59
143_I258_E0.5460.59
355_N370_F0.5460.59
93_F130_Y0.5440.59
328_L331_Y0.5420.59
516_G525_A0.5420.59
514_S524_L0.5410.59
50_L53_L0.5410.59
501_F520_L0.5400.58
104_S107_M0.5390.58
469_F476_V0.5380.58
355_N362_V0.5380.58
93_F261_Y0.5370.58
372_F451_G0.5370.58
11_L16_L0.5360.58
317_Q377_L0.5360.58
367_A474_F0.5350.58
445_G450_L0.5350.58
513_L538_E0.5350.58
513_L531_R0.5350.58
121_I386_R0.5340.58
491_L510_E0.5330.58
361_F369_R0.5320.57
324_L331_Y0.5310.57
448_V530_L0.5310.57
516_G524_L0.5310.57
502_R514_S0.5300.57
303_L390_L0.5280.57
178_G430_L0.5270.57
375_V399_K0.5260.57
334_N370_F0.5260.57
70_L152_T0.5260.57
24_L27_L0.5260.57
156_V164_A0.5230.56
519_L531_R0.5220.56
292_R480_L0.5220.56
217_S455_P0.5220.56
376_S455_P0.5220.56
430_L434_V0.5210.56
97_F250_V0.5210.56
176_A254_A0.5210.56
514_S526_T0.5190.56
503_G524_L0.5190.56
18_L24_L0.5180.55
10_L13_L0.5180.55
131_L134_L0.5180.55
93_F99_E0.5180.55
22_A26_G0.5160.55
508_G523_L0.5160.55
498_A509_A0.5150.55
414_L449_G0.5150.55
288_R292_R0.5150.55
374_A399_K0.5140.55
355_N369_R0.5140.55
71_S75_L0.5130.55
507_S519_L0.5130.55
507_S525_A0.5130.55
94_L98_L0.5130.55
292_R519_L0.5130.55
429_M432_S0.5120.55
331_Y451_G0.5120.55
51_S411_A0.5110.54
504_R525_A0.5100.54
170_L174_L0.5090.54
306_K321_L0.5080.54
306_K313_R0.5080.54
510_E538_E0.5080.54
97_F262_F0.5080.54
508_G531_R0.5070.54
106_W114_P0.5060.54
516_G535_R0.5060.54
386_R392_L0.5060.54
114_P355_N0.5060.54
245_T249_L0.5050.54
275_R280_K0.5050.54
73_L162_R0.5040.53
216_P313_R0.5030.53
510_E520_L0.5030.53
359_A418_S0.5030.53
41_L53_L0.5020.53
19_L528_L0.5020.53
331_Y373_P0.5010.53
106_W118_A0.5000.53
425_S497_L0.5000.53
364_A369_R0.5000.53
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2jlnA 1 0.286 7 0.975 Contact Map
4m64A 1 0.7325 6.6 0.975 Contact Map
3giaA 1 0.262 4.9 0.977 Contact Map
3l1lA 2 0.2583 4.9 0.977 Contact Map
4gycB 2 0.1033 2.4 0.98 Contact Map
4b19A 1 0.0554 2.1 0.981 Contact Map
2kv5A 1 0.0609 1.7 0.982 Contact Map
2m20A 2 0.0683 1.6 0.982 Contact Map
1q90G 1 0.0554 1.4 0.983 Contact Map
2ksfA 1 0.1956 1.4 0.983 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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