ABC_tran_2 - PFAM28P - GREMLIN Contacts

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ABC_tran_2 - Putative ATP-binding cassette

PFAM:	PF16949	Sequences: SRLRGSRLRLLLLGLLGLLFWAGLFGLFYRVLRYLRSVEELGDLLAEKLLSLLFLTFFSMLLFSNIITALSTLFLSRDLELLLSLPVSPRRIFLAKFLETLLYSSWMVLLFGLPVLLAYGIVYGAGWLFYLLALLVLLPFLVIPAALGSLLTLLLVRVFPARRARDILLLLGLLLAAGLVLLFRLLRRPERLVNPEFASLVDFLASLRTPSSPLLPSTWAAEALLAALRGDLGEALFYLLLLLSTALALVVLAAWLAERLYFKGWSKAQESRAARRFKRKRWSRRLDRLLRRLRPLSPPVRALLLKDLRLFFRDPTQWSQLLLLFALLVVYLYNFRVLPLDLSSPFLQNLISFLNLGLAGFVLAALAARFVFPAVSLEGRAFWILRSSPLSLRRLLWSKFWFGLLPLLVLALLLIVLSNLLLGVSPFMMLLSLVTILLLTFGLVGLAVGLGALYPNFKEENPAQIVTSFGGLLFMVLSLLYIGLVIVLEALPVYLYLAARFRGRLLSGAELALSLGLALLLSLLATLLPLRLGLRRLERLEF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	542 (530)
Sequences:	2744 (2259)
Seq/√Len:	98.1
META:	0.909

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
120_G	130_Y	4.813	1.00
120_G	129_F	4.376	1.00
385_L	395_L	3.960	1.00
74_F	264_G	3.923	1.00
74_F	153_L	3.851	1.00
136_V	220_A	3.579	1.00
435_T	489_E	3.481	1.00
189_P	192_L	3.385	1.00
188_R	191_R	3.371	1.00
449_G	452_A	3.142	1.00
25_F	121_I	3.138	1.00
305_L	309_R	2.937	1.00
361_F	365_A	2.888	1.00
525_A	529_P	2.740	1.00
93_F	253_A	2.728	1.00
449_G	533_G	2.643	1.00
442_G	481_Y	2.602	1.00
101_L	105_S	2.549	1.00
514_S	518_A	2.546	1.00
188_R	192_L	2.541	1.00
61_L	64_S	2.500	1.00
150_L	256_L	2.464	1.00
499_A	503_G	2.442	1.00
90_R	258_E	2.433	1.00
307_D	403_G	2.398	1.00
189_P	193_V	2.366	1.00
524_L	528_L	2.351	1.00
445_G	449_G	2.337	1.00
65_N	145_A	2.306	1.00
515_L	518_A	2.293	1.00
521_L	525_A	2.270	1.00
481_Y	522_S	2.269	1.00
216_P	219_W	2.269	1.00
460_E	464_Q	2.203	1.00
522_S	525_A	2.154	1.00
513_L	517_L	2.150	1.00
459_E	462_P	2.143	1.00
120_G	125_A	2.102	1.00
518_A	522_S	2.099	1.00
511_L	514_S	2.098	1.00
248_A	251_V	2.097	1.00
139_P	243_L	2.089	1.00
257_A	261_Y	2.021	1.00
452_A	533_G	2.009	1.00
13_L	16_L	2.006	1.00
412_L	437_L	1.982	1.00
447_A	474_F	1.972	1.00
143_I	249_L	1.972	1.00
148_G	152_T	1.958	1.00
416_V	433_L	1.937	1.00
511_L	515_L	1.933	1.00
127_W	131_L	1.903	1.00
382_F	457_F	1.900	1.00
311_F	318_W	1.838	1.00
177_A	181_L	1.836	1.00
523_L	527_L	1.833	1.00
11_L	15_L	1.825	1.00
522_S	526_T	1.813	1.00
528_L	532_L	1.800	1.00
190_E	193_V	1.796	1.00
242_L	245_T	1.782	1.00
12_L	15_L	1.777	1.00
518_A	521_L	1.761	1.00
527_L	531_R	1.752	1.00
507_S	510_E	1.752	1.00
306_K	385_L	1.738	1.00
150_L	253_A	1.731	1.00
320_Q	331_Y	1.727	1.00
472_L	475_M	1.725	1.00
408_L	437_L	1.715	1.00
203_F	207_L	1.696	1.00
498_A	502_R	1.695	1.00
125_A	130_Y	1.680	1.00
294_R	297_S	1.679	1.00
501_F	505_L	1.677	1.00
236_L	240_L	1.676	1.00
61_L	65_N	1.665	1.00
189_P	194_N	1.658	1.00
78_D	81_L	1.652	1.00
317_Q	320_Q	1.652	1.00
404_L	441_F	1.647	1.00
439_L	481_Y	1.647	1.00
467_T	470_G	1.640	1.00
375_V	396_L	1.611	1.00
377_L	465_I	1.607	1.00
465_I	468_S	1.605	1.00
408_L	412_L	1.601	1.00
114_P	118_A	1.593	1.00
118_A	122_V	1.584	1.00
38_V	41_L	1.560	1.00
136_V	223_A	1.559	1.00
514_S	517_L	1.557	1.00
510_E	514_S	1.557	1.00
516_G	519_L	1.555	1.00
498_A	501_F	1.551	1.00
191_R	194_N	1.551	1.00
502_R	507_S	1.531	1.00
400_F	445_G	1.513	1.00
64_S	67_I	1.512	1.00
153_L	257_A	1.508	1.00
369_R	373_P	1.506	1.00
499_A	502_R	1.500	1.00
237_F	244_S	1.499	1.00
499_A	504_R	1.498	1.00
488_L	492_P	1.487	1.00
331_Y	355_N	1.487	1.00
518_A	526_T	1.487	1.00
503_G	508_G	1.486	1.00
498_A	503_G	1.485	1.00
484_L	521_L	1.482	1.00
504_R	507_S	1.473	1.00
18_L	22_A	1.464	1.00
518_A	525_A	1.458	1.00
163_R	166_D	1.451	1.00
176_A	180_V	1.448	1.00
295_P	298_P	1.441	1.00
9_R	16_L	1.438	1.00
180_V	183_F	1.438	1.00
515_L	519_L	1.438	1.00
378_E	399_K	1.432	1.00
256_L	260_L	1.428	1.00
501_F	504_R	1.423	1.00
96_K	99_E	1.420	1.00
70_L	75_L	1.416	1.00
241_L	245_T	1.407	1.00
391_S	394_R	1.404	1.00
445_G	448_V	1.402	1.00
501_F	507_S	1.402	1.00
14_G	18_L	1.400	0.99
376_S	465_I	1.397	0.99
15_L	19_L	1.396	0.99
240_L	243_L	1.393	0.99
179_L	183_F	1.389	0.99
505_L	520_L	1.380	0.99
503_G	507_S	1.380	0.99
44_L	48_K	1.369	0.99
248_A	252_L	1.365	0.99
459_E	464_Q	1.365	0.99
508_G	515_L	1.364	0.99
500_R	503_G	1.362	0.99
369_R	372_F	1.359	0.99
507_S	516_G	1.356	0.99
307_D	313_R	1.349	0.99
23_G	28_F	1.347	0.99
153_L	261_Y	1.344	0.99
320_Q	355_N	1.341	0.99
445_G	451_G	1.339	0.99
292_R	295_P	1.338	0.99
510_E	513_L	1.330	0.99
501_F	512_A	1.321	0.99
426_P	430_L	1.320	0.99
517_L	521_L	1.319	0.99
168_L	171_L	1.312	0.99
506_L	509_A	1.310	0.99
505_L	509_A	1.310	0.99
332_L	421_L	1.308	0.99
507_S	514_S	1.305	0.99
509_A	515_L	1.300	0.99
400_F	448_V	1.298	0.99
485_V	489_E	1.294	0.99
500_R	504_R	1.293	0.99
510_E	516_G	1.292	0.99
187_R	192_L	1.291	0.99
193_V	197_F	1.289	0.99
383_W	387_S	1.287	0.99
322_L	371_V	1.284	0.99
468_S	471_G	1.277	0.99
38_V	43_D	1.267	0.99
532_L	536_R	1.265	0.99
161_A	166_D	1.260	0.99
101_L	145_A	1.260	0.99
498_A	506_L	1.256	0.99
157_R	264_G	1.253	0.99
508_G	512_A	1.252	0.99
502_R	510_E	1.247	0.99
303_L	398_S	1.246	0.99
509_A	512_A	1.242	0.99
153_L	256_L	1.240	0.99
169_L	172_G	1.239	0.99
500_R	510_E	1.239	0.99
517_L	522_S	1.234	0.99
141_L	144_P	1.233	0.99
506_L	510_E	1.227	0.99
504_R	510_E	1.223	0.99
132_L	227_A	1.220	0.99
42_G	45_L	1.213	0.99
371_V	403_G	1.209	0.99
371_V	444_V	1.207	0.98
307_D	398_S	1.206	0.98
504_R	520_L	1.206	0.98
505_L	511_L	1.205	0.98
512_A	515_L	1.205	0.98
181_L	185_L	1.203	0.98
368_A	371_V	1.201	0.98
74_F	156_V	1.197	0.98
505_L	510_E	1.197	0.98
25_F	29_Y	1.197	0.98
111_F	115_V	1.192	0.98
501_F	515_L	1.191	0.98
404_L	408_L	1.188	0.98
450_L	477_L	1.188	0.98
193_V	196_E	1.185	0.98
514_S	525_A	1.184	0.98
516_G	520_L	1.183	0.98
116_L	133_A	1.181	0.98
88_S	91_R	1.178	0.98
503_G	523_L	1.176	0.98
306_K	399_K	1.175	0.98
194_N	197_F	1.168	0.98
503_G	511_L	1.165	0.98
38_V	54_F	1.163	0.98
397_W	530_L	1.163	0.98
505_L	523_L	1.161	0.98
237_F	240_L	1.152	0.98
509_A	514_S	1.151	0.98
499_A	505_L	1.150	0.98
275_R	278_K	1.148	0.98
501_F	511_L	1.146	0.98
507_S	512_A	1.142	0.98
504_R	519_L	1.141	0.98
468_S	475_M	1.140	0.98
192_L	195_P	1.126	0.98
498_A	504_R	1.124	0.98
29_Y	121_I	1.122	0.98
375_V	452_A	1.120	0.98
513_L	516_G	1.118	0.97
13_L	18_L	1.114	0.97
504_R	508_G	1.114	0.97
502_R	513_L	1.114	0.97
303_L	307_D	1.113	0.97
159_F	162_R	1.110	0.97
30_R	34_Y	1.109	0.97
31_V	34_Y	1.109	0.97
503_G	515_L	1.107	0.97
93_F	257_A	1.106	0.97
501_F	508_G	1.105	0.97
512_A	517_L	1.105	0.97
95_A	99_E	1.104	0.97
10_L	15_L	1.104	0.97
38_V	42_G	1.103	0.97
181_L	184_R	1.101	0.97
504_R	515_L	1.095	0.97
299_P	302_A	1.093	0.97
506_L	513_L	1.093	0.97
267_K	270_E	1.091	0.97
244_S	248_A	1.088	0.97
528_L	531_R	1.087	0.97
66_I	151_L	1.087	0.97
499_A	507_S	1.085	0.97
89_P	262_F	1.083	0.97
74_F	257_A	1.083	0.97
508_G	516_G	1.082	0.97
105_S	108_V	1.082	0.97
314_D	317_Q	1.080	0.97
23_G	26_G	1.080	0.97
188_R	194_N	1.079	0.97
456_N	459_E	1.076	0.97
64_S	369_R	1.075	0.97
533_G	536_R	1.075	0.97
140_F	220_A	1.070	0.97
521_L	526_T	1.068	0.97
513_L	521_L	1.064	0.97
509_A	523_L	1.061	0.97
505_L	517_L	1.059	0.97
42_G	47_E	1.059	0.97
369_R	451_G	1.059	0.97
65_N	68_T	1.058	0.97
64_S	355_N	1.057	0.96
312_F	315_P	1.057	0.96
415_I	436_I	1.057	0.96
509_A	513_L	1.056	0.96
509_A	531_R	1.054	0.96
503_G	506_L	1.051	0.96
504_R	511_L	1.051	0.96
498_A	516_G	1.045	0.96
504_R	513_L	1.045	0.96
65_N	69_A	1.033	0.96
277_F	280_K	1.033	0.96
416_V	420_L	1.032	0.96
359_A	362_V	1.030	0.96
187_R	190_E	1.026	0.96
531_R	534_L	1.021	0.96
82_L	96_K	1.020	0.96
81_L	84_S	1.018	0.96
506_L	514_S	1.015	0.96
504_R	521_L	1.013	0.96
380_R	458_K	1.012	0.95
246_A	250_V	1.011	0.95
97_F	149_S	1.009	0.95
168_L	172_G	1.009	0.95
507_S	515_L	1.005	0.95
527_L	530_L	1.000	0.95
521_L	524_L	0.999	0.95
144_P	455_P	0.998	0.95
105_S	141_L	0.988	0.95
471_G	475_M	0.985	0.95
499_A	511_L	0.977	0.95
442_G	445_G	0.977	0.95
511_L	517_L	0.974	0.94
499_A	508_G	0.973	0.94
507_S	511_L	0.968	0.94
459_E	465_I	0.967	0.94
510_E	517_L	0.966	0.94
499_A	510_E	0.964	0.94
77_R	80_E	0.964	0.94
188_R	193_V	0.963	0.94
125_A	129_F	0.962	0.94
306_K	381_A	0.959	0.94
162_R	165_R	0.958	0.94
514_S	522_S	0.958	0.94
268_A	271_S	0.954	0.94
506_L	517_L	0.953	0.94
498_A	507_S	0.951	0.94
500_R	507_S	0.950	0.94
462_P	466_V	0.950	0.94
57_F	65_N	0.947	0.94
57_F	64_S	0.947	0.94
470_G	475_M	0.946	0.94
502_R	512_A	0.944	0.93
508_G	511_L	0.941	0.93
250_V	254_A	0.941	0.93
511_L	522_S	0.940	0.93
506_L	515_L	0.940	0.93
500_R	505_L	0.939	0.93
238_Y	242_L	0.936	0.93
9_R	15_L	0.930	0.93
335_F	358_L	0.927	0.93
154_L	260_L	0.925	0.93
499_A	506_L	0.924	0.93
373_P	451_G	0.923	0.93
508_G	514_S	0.920	0.93
508_G	517_L	0.920	0.93
376_S	379_G	0.918	0.93
309_R	313_R	0.917	0.92
92_I	257_A	0.917	0.92
182_L	186_L	0.916	0.92
467_T	471_G	0.910	0.92
531_R	535_R	0.906	0.92
396_L	448_V	0.906	0.92
502_R	506_L	0.906	0.92
239_L	505_L	0.906	0.92
515_L	526_T	0.902	0.92
222_E	238_Y	0.901	0.92
527_L	532_L	0.899	0.92
508_G	524_L	0.897	0.92
506_L	524_L	0.895	0.92
517_L	526_T	0.895	0.92
318_W	386_R	0.894	0.92
200_L	476_V	0.894	0.92
129_F	133_A	0.890	0.91
64_S	114_P	0.890	0.91
505_L	514_S	0.887	0.91
504_R	509_A	0.887	0.91
534_L	538_E	0.886	0.91
276_R	279_R	0.884	0.91
325_F	328_L	0.881	0.91
466_V	470_G	0.880	0.91
499_A	513_L	0.878	0.91
13_L	19_L	0.877	0.91
156_V	267_K	0.874	0.91
248_A	280_K	0.872	0.90
9_R	12_L	0.872	0.90
500_R	520_L	0.871	0.90
259_R	263_K	0.871	0.90
144_P	203_F	0.870	0.90
500_R	511_L	0.870	0.90
514_S	519_L	0.870	0.90
436_I	440_T	0.868	0.90
502_R	505_L	0.866	0.90
500_R	506_L	0.866	0.90
471_G	474_F	0.865	0.90
495_L	510_E	0.865	0.90
73_L	97_F	0.862	0.90
19_L	22_A	0.861	0.90
85_L	388_S	0.859	0.90
10_L	18_L	0.858	0.90
94_L	250_V	0.857	0.90
520_L	524_L	0.855	0.90
439_L	443_L	0.850	0.89
510_E	515_L	0.847	0.89
69_A	152_T	0.843	0.89
187_R	191_R	0.842	0.89
24_L	28_F	0.840	0.89
515_L	521_L	0.839	0.89
532_L	535_R	0.839	0.89
181_L	256_L	0.836	0.89
502_R	508_G	0.834	0.88
509_A	516_G	0.833	0.88
502_R	523_L	0.833	0.88
22_A	25_F	0.831	0.88
469_F	473_L	0.830	0.88
240_L	244_S	0.828	0.88
230_G	235_A	0.828	0.88
373_P	377_L	0.826	0.88
255_W	258_E	0.824	0.88
121_I	129_F	0.821	0.88
503_G	513_L	0.820	0.88
504_R	527_L	0.818	0.87
32_L	35_L	0.818	0.87
503_G	510_E	0.817	0.87
65_N	104_S	0.817	0.87
508_G	513_L	0.813	0.87
99_E	373_P	0.810	0.87
367_A	447_A	0.810	0.87
179_L	182_L	0.809	0.87
74_F	157_R	0.808	0.87
436_I	439_L	0.807	0.87
501_F	513_L	0.806	0.87
481_Y	489_E	0.806	0.87
49_L	53_L	0.806	0.87
241_L	244_S	0.806	0.87
190_E	194_N	0.803	0.86
506_L	511_L	0.802	0.86
393_R	397_W	0.801	0.86
304_L	398_S	0.799	0.86
353_F	356_L	0.799	0.86
176_A	182_L	0.799	0.86
153_L	260_L	0.797	0.86
354_L	357_G	0.796	0.86
106_W	369_R	0.796	0.86
75_L	78_D	0.795	0.86
318_W	334_N	0.795	0.86
309_R	312_F	0.793	0.86
215_L	219_W	0.791	0.86
140_F	144_P	0.791	0.86
505_L	508_G	0.789	0.85
177_A	182_L	0.789	0.85
131_L	146_A	0.787	0.85
189_P	195_P	0.786	0.85
216_P	221_A	0.784	0.85
498_A	513_L	0.783	0.85
112_G	368_A	0.783	0.85
501_F	518_A	0.782	0.85
388_S	395_L	0.779	0.85
529_P	532_L	0.778	0.85
302_A	371_V	0.778	0.85
510_E	526_T	0.778	0.85
514_S	521_L	0.778	0.85
468_S	472_L	0.775	0.84
146_A	149_S	0.773	0.84
15_L	18_L	0.772	0.84
518_A	523_L	0.771	0.84
275_R	279_R	0.771	0.84
502_R	516_G	0.770	0.84
313_R	451_G	0.768	0.84
320_Q	369_R	0.768	0.84
278_K	285_R	0.767	0.84
184_R	189_P	0.766	0.84
47_E	51_S	0.764	0.84
504_R	514_S	0.763	0.84
451_G	455_P	0.762	0.83
329_V	417_L	0.761	0.83
276_R	536_R	0.759	0.83
219_W	318_W	0.758	0.83
177_A	184_R	0.757	0.83
303_L	385_L	0.755	0.83
393_R	538_E	0.755	0.83
17_G	21_W	0.753	0.83
498_A	512_A	0.751	0.83
504_R	517_L	0.747	0.82
101_L	141_L	0.747	0.82
117_L	121_I	0.745	0.82
347_L	387_S	0.744	0.82
365_A	407_L	0.742	0.82
120_G	264_G	0.741	0.82
85_L	89_P	0.741	0.82
299_P	394_R	0.738	0.81
72_T	76_S	0.737	0.81
158_V	165_R	0.736	0.81
13_L	20_F	0.732	0.81
487_V	502_R	0.730	0.81
152_T	156_V	0.730	0.81
80_E	84_S	0.730	0.81
524_L	527_L	0.729	0.81
373_P	470_G	0.727	0.80
220_A	224_L	0.727	0.80
505_L	519_L	0.726	0.80
508_G	518_A	0.722	0.80
498_A	514_S	0.722	0.80
501_F	516_G	0.721	0.80
104_S	372_F	0.720	0.80
449_G	454_Y	0.719	0.80
104_S	373_P	0.719	0.80
260_L	438_L	0.718	0.80
302_A	306_K	0.717	0.80
39_E	248_A	0.717	0.80
231_D	234_E	0.716	0.79
57_F	61_L	0.715	0.79
128_L	131_L	0.709	0.79
42_G	48_K	0.708	0.79
513_L	526_T	0.708	0.79
345_P	348_Q	0.706	0.79
160_P	166_D	0.706	0.79
10_L	14_G	0.706	0.79
83_L	92_I	0.704	0.78
443_L	478_S	0.704	0.78
133_A	224_L	0.704	0.78
153_L	264_G	0.703	0.78
456_N	464_Q	0.701	0.78
160_P	163_R	0.701	0.78
205_A	208_R	0.701	0.78
355_N	372_F	0.698	0.78
509_A	517_L	0.698	0.78
428_M	431_L	0.697	0.78
309_R	317_Q	0.695	0.77
306_K	318_W	0.694	0.77
507_S	513_L	0.692	0.77
466_V	475_M	0.692	0.77
519_L	523_L	0.690	0.77
495_L	500_R	0.689	0.77
28_F	32_L	0.689	0.77
88_S	226_A	0.688	0.77
218_T	222_E	0.686	0.77
184_R	187_R	0.685	0.76
83_L	261_Y	0.684	0.76
82_L	87_V	0.683	0.76
442_G	449_G	0.682	0.76
238_Y	241_L	0.682	0.76
454_Y	470_G	0.682	0.76
49_L	56_T	0.682	0.76
465_I	470_G	0.680	0.76
331_Y	334_N	0.680	0.76
219_W	383_W	0.680	0.76
242_L	248_A	0.678	0.76
116_L	224_L	0.677	0.76
266_S	270_E	0.677	0.76
64_S	471_G	0.676	0.75
459_E	467_T	0.675	0.75
511_L	518_A	0.674	0.75
507_S	518_A	0.674	0.75
278_K	281_R	0.673	0.75
92_I	96_K	0.672	0.75
79_L	261_Y	0.671	0.75
16_L	20_F	0.670	0.75
160_P	314_D	0.669	0.75
97_F	144_P	0.669	0.75
367_A	443_L	0.669	0.75
54_F	314_D	0.668	0.75
469_F	475_M	0.667	0.75
320_Q	463_A	0.667	0.75
500_R	512_A	0.666	0.74
138_L	290_L	0.664	0.74
104_S	319_S	0.664	0.74
292_R	297_S	0.661	0.74
516_G	527_L	0.659	0.74
223_A	244_S	0.658	0.74
503_G	509_A	0.657	0.73
39_E	46_A	0.654	0.73
306_K	314_D	0.653	0.73
496_Y	499_A	0.653	0.73
505_L	524_L	0.651	0.73
106_W	355_N	0.650	0.73
520_L	528_L	0.650	0.73
448_V	452_A	0.649	0.72
68_T	72_T	0.649	0.72
489_E	494_Y	0.648	0.72
521_L	528_L	0.647	0.72
511_L	520_L	0.646	0.72
373_P	376_S	0.645	0.72
449_G	529_P	0.645	0.72
29_Y	33_R	0.645	0.72
525_A	528_L	0.644	0.72
498_A	510_E	0.643	0.72
22_A	29_Y	0.642	0.72
333_Y	337_V	0.641	0.72
504_R	512_A	0.641	0.72
517_L	532_L	0.640	0.71
464_Q	469_F	0.639	0.71
457_F	461_N	0.638	0.71
293_L	298_P	0.636	0.71
358_L	362_V	0.635	0.71
434_V	512_A	0.634	0.71
466_V	471_G	0.634	0.71
461_N	466_V	0.633	0.71
304_L	402_F	0.633	0.71
510_E	518_A	0.632	0.70
159_F	169_L	0.630	0.70
514_S	523_L	0.629	0.70
112_G	133_A	0.629	0.70
57_F	67_I	0.628	0.70
507_S	524_L	0.628	0.70
511_L	516_G	0.627	0.70
106_W	331_Y	0.626	0.70
512_A	526_T	0.625	0.70
508_G	519_L	0.624	0.70
412_L	433_L	0.624	0.70
512_A	516_G	0.624	0.70
326_A	334_N	0.624	0.70
20_F	35_L	0.623	0.69
467_T	472_L	0.623	0.69
404_L	437_L	0.622	0.69
487_V	516_G	0.621	0.69
352_S	356_L	0.620	0.69
365_A	411_A	0.620	0.69
512_A	525_A	0.620	0.69
507_S	527_L	0.619	0.69
264_G	314_D	0.619	0.69
62_L	65_N	0.618	0.69
529_P	534_L	0.617	0.69
148_G	369_R	0.616	0.69
227_A	235_A	0.616	0.69
58_F	64_S	0.611	0.68
513_L	520_L	0.611	0.68
76_S	96_K	0.610	0.68
375_V	410_L	0.607	0.67
146_A	253_A	0.607	0.67
69_A	100_T	0.607	0.67
453_L	456_N	0.607	0.67
181_L	205_A	0.605	0.67
525_A	536_R	0.605	0.67
313_R	320_Q	0.604	0.67
334_N	369_R	0.604	0.67
503_G	520_L	0.604	0.67
487_V	513_L	0.602	0.67
443_L	449_G	0.602	0.67
114_P	383_W	0.602	0.67
41_L	204_L	0.601	0.67
48_K	51_S	0.601	0.67
503_G	535_R	0.599	0.66
502_R	511_L	0.598	0.66
314_D	319_S	0.597	0.66
320_Q	324_L	0.596	0.66
64_S	331_Y	0.596	0.66
159_F	165_R	0.596	0.66
439_L	485_V	0.596	0.66
509_A	520_L	0.595	0.66
292_R	524_L	0.595	0.66
64_S	334_N	0.595	0.66
237_F	241_L	0.594	0.66
507_S	517_L	0.593	0.66
301_R	305_L	0.593	0.66
10_L	16_L	0.593	0.66
262_F	265_W	0.592	0.66
500_R	525_A	0.592	0.66
316_T	376_S	0.592	0.66
518_A	524_L	0.592	0.66
307_D	395_L	0.591	0.65
528_L	535_R	0.590	0.65
51_S	54_F	0.589	0.65
56_T	150_L	0.588	0.65
108_V	334_N	0.586	0.65
442_G	446_L	0.586	0.65
174_L	391_S	0.586	0.65
470_G	474_F	0.585	0.65
498_A	505_L	0.584	0.64
501_F	534_L	0.584	0.64
55_L	217_S	0.584	0.64
525_A	532_L	0.583	0.64
105_S	470_G	0.583	0.64
495_L	498_A	0.581	0.64
40_E	44_L	0.581	0.64
274_A	279_R	0.581	0.64
501_F	506_L	0.580	0.64
40_E	43_D	0.578	0.64
375_V	395_L	0.577	0.64
516_G	522_S	0.577	0.64
513_L	518_A	0.576	0.63
154_L	299_P	0.576	0.63
310_L	313_R	0.576	0.63
318_W	422_L	0.575	0.63
146_A	249_L	0.575	0.63
500_R	528_L	0.574	0.63
524_L	535_R	0.573	0.63
512_A	518_A	0.572	0.63
307_D	315_P	0.570	0.63
373_P	465_I	0.569	0.62
530_L	534_L	0.569	0.62
306_K	378_E	0.568	0.62
189_P	197_F	0.568	0.62
477_L	480_L	0.568	0.62
512_A	520_L	0.568	0.62
284_R	287_D	0.567	0.62
533_G	537_L	0.566	0.62
265_W	303_L	0.566	0.62
526_T	529_P	0.566	0.62
437_L	445_G	0.564	0.62
509_A	521_L	0.564	0.62
523_L	526_T	0.564	0.62
58_F	217_S	0.563	0.62
58_F	144_P	0.563	0.62
332_L	417_L	0.562	0.62
263_K	267_K	0.562	0.62
187_R	193_V	0.562	0.62
121_I	125_A	0.559	0.61
27_L	31_V	0.559	0.61
484_L	517_L	0.559	0.61
160_P	164_A	0.559	0.61
140_F	217_S	0.558	0.61
300_V	401_W	0.558	0.61
42_G	46_A	0.557	0.61
524_L	529_P	0.556	0.61
512_A	521_L	0.555	0.61
515_L	522_S	0.555	0.61
511_L	528_L	0.555	0.61
257_A	264_G	0.555	0.61
9_R	13_L	0.554	0.60
501_F	510_E	0.553	0.60
285_R	288_R	0.553	0.60
321_L	361_F	0.553	0.60
69_A	148_G	0.551	0.60
461_N	465_I	0.551	0.60
500_R	514_S	0.549	0.60
487_V	538_E	0.549	0.60
107_M	324_L	0.549	0.60
151_L	514_S	0.548	0.60
392_L	395_L	0.548	0.60
463_A	467_T	0.548	0.60
515_L	525_A	0.548	0.60
73_L	92_I	0.548	0.60
451_G	454_Y	0.547	0.59
515_L	528_L	0.546	0.59
143_I	258_E	0.546	0.59
355_N	370_F	0.546	0.59
93_F	130_Y	0.544	0.59
328_L	331_Y	0.542	0.59
516_G	525_A	0.542	0.59
514_S	524_L	0.541	0.59
50_L	53_L	0.541	0.59
501_F	520_L	0.540	0.58
104_S	107_M	0.539	0.58
469_F	476_V	0.538	0.58
355_N	362_V	0.538	0.58
93_F	261_Y	0.537	0.58
372_F	451_G	0.537	0.58
11_L	16_L	0.536	0.58
317_Q	377_L	0.536	0.58
367_A	474_F	0.535	0.58
445_G	450_L	0.535	0.58
513_L	538_E	0.535	0.58
513_L	531_R	0.535	0.58
121_I	386_R	0.534	0.58
491_L	510_E	0.533	0.58
361_F	369_R	0.532	0.57
324_L	331_Y	0.531	0.57
448_V	530_L	0.531	0.57
516_G	524_L	0.531	0.57
502_R	514_S	0.530	0.57
303_L	390_L	0.528	0.57
178_G	430_L	0.527	0.57
375_V	399_K	0.526	0.57
334_N	370_F	0.526	0.57
70_L	152_T	0.526	0.57
24_L	27_L	0.526	0.57
156_V	164_A	0.523	0.56
519_L	531_R	0.522	0.56
292_R	480_L	0.522	0.56
217_S	455_P	0.522	0.56
376_S	455_P	0.522	0.56
430_L	434_V	0.521	0.56
97_F	250_V	0.521	0.56
176_A	254_A	0.521	0.56
514_S	526_T	0.519	0.56
503_G	524_L	0.519	0.56
18_L	24_L	0.518	0.55
10_L	13_L	0.518	0.55
131_L	134_L	0.518	0.55
93_F	99_E	0.518	0.55
22_A	26_G	0.516	0.55
508_G	523_L	0.516	0.55
498_A	509_A	0.515	0.55
414_L	449_G	0.515	0.55
288_R	292_R	0.515	0.55
374_A	399_K	0.514	0.55
355_N	369_R	0.514	0.55
71_S	75_L	0.513	0.55
507_S	519_L	0.513	0.55
507_S	525_A	0.513	0.55
94_L	98_L	0.513	0.55
292_R	519_L	0.513	0.55
429_M	432_S	0.512	0.55
331_Y	451_G	0.512	0.55
51_S	411_A	0.511	0.54
504_R	525_A	0.510	0.54
170_L	174_L	0.509	0.54
306_K	321_L	0.508	0.54
306_K	313_R	0.508	0.54
510_E	538_E	0.508	0.54
97_F	262_F	0.508	0.54
508_G	531_R	0.507	0.54
106_W	114_P	0.506	0.54
516_G	535_R	0.506	0.54
386_R	392_L	0.506	0.54
114_P	355_N	0.506	0.54
245_T	249_L	0.505	0.54
275_R	280_K	0.505	0.54
73_L	162_R	0.504	0.53
216_P	313_R	0.503	0.53
510_E	520_L	0.503	0.53
359_A	418_S	0.503	0.53
41_L	53_L	0.502	0.53
19_L	528_L	0.502	0.53
331_Y	373_P	0.501	0.53
106_W	118_A	0.500	0.53
425_S	497_L	0.500	0.53
364_A	369_R	0.500	0.53

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2jlnA	1	0.286	7	0.975	Contact Map
4m64A	1	0.7325	6.6	0.975	Contact Map
3giaA	1	0.262	4.9	0.977	Contact Map
3l1lA	2	0.2583	4.9	0.977	Contact Map
4gycB	2	0.1033	2.4	0.98	Contact Map
4b19A	1	0.0554	2.1	0.981	Contact Map
2kv5A	1	0.0609	1.7	0.982	Contact Map
2m20A	2	0.0683	1.6	0.982	Contact Map
1q90G	1	0.0554	1.4	0.983	Contact Map
2ksfA	1	0.1956	1.4	0.983	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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