GREMLIN Database
putAbiC - Putative phage abortive infection protein
PFAM: PF16872 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 82 (78)
Sequences: 2730 (2438)
Seq/√Len: 276.0
META: 0.85

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
21_D70_K4.0091.00
55_C68_I3.2581.00
17_L36_A3.0601.00
13_L39_L2.8351.00
21_D71_Y2.3241.00
15_Q37_K2.0161.00
12_N42_Q1.9371.00
65_K69_E1.9101.00
68_I73_L1.9071.00
16_I39_L1.8701.00
69_E72_N1.7941.00
68_I74_L1.7591.00
20_I36_A1.7521.00
17_L73_L1.7261.00
17_L39_L1.6951.00
14_Y54_N1.6541.00
3_Q45_N1.5081.00
22_E34_K1.5061.00
46_Y49_L1.4991.00
33_K72_N1.4901.00
11_R54_N1.4511.00
27_L31_E1.4211.00
7_G11_R1.3761.00
9_Y47_E1.3701.00
44_S47_E1.3611.00
2_H5_D1.3071.00
57_S60_G1.3031.00
21_D67_L1.2591.00
49_L53_Y1.2551.00
33_K37_K1.2301.00
28_S31_E1.2291.00
37_K75_K1.1961.00
18_K37_K1.1871.00
40_R75_K1.1791.00
18_K22_E1.1781.00
4_S46_Y1.0761.00
40_R54_N1.0421.00
37_K40_R1.0181.00
49_L77_L0.9901.00
7_G45_N0.9701.00
36_A71_Y0.9561.00
43_L51_L0.9511.00
34_K38_I0.9431.00
10_F50_L0.9231.00
24_E32_K0.9171.00
13_L51_L0.8991.00
20_I32_K0.8781.00
3_Q78_P0.8771.00
21_D32_K0.8701.00
40_R43_L0.8401.00
54_N76_N0.8311.00
17_L64_F0.8281.00
19_F34_K0.8240.99
33_K36_A0.8160.99
12_N16_I0.8150.99
23_S32_K0.8100.99
62_E66_P0.8000.99
15_Q18_K0.7990.99
43_L47_E0.7980.99
12_N76_N0.7760.99
6_L50_L0.7670.99
23_S27_L0.7420.99
10_F51_L0.7330.99
48_L74_L0.7320.99
15_Q38_I0.7150.99
49_L79_L0.7010.98
29_E33_K0.7000.98
15_Q75_K0.6950.98
31_E34_K0.6700.98
23_S34_K0.6550.97
14_Y40_R0.6530.97
14_Y63_K0.6470.97
42_Q47_E0.6470.97
14_Y18_K0.6470.97
60_G63_K0.6410.97
58_E61_K0.6400.97
26_D29_E0.6310.97
22_E26_D0.6300.97
27_L32_K0.6220.97
55_C64_F0.6200.96
23_S29_E0.6170.96
45_N78_P0.6150.96
72_N75_K0.6080.96
20_I39_L0.6030.96
66_P69_E0.6030.96
52_F75_K0.6020.96
17_L20_I0.5940.95
52_F55_C0.5900.95
17_L67_L0.5890.95
56_L65_K0.5840.95
13_L64_F0.5770.95
40_R76_N0.5710.94
11_R40_R0.5670.94
11_R76_N0.5660.94
58_E79_L0.5590.94
19_F38_I0.5560.94
15_Q41_A0.5520.93
22_E29_E0.5510.93
72_N76_N0.5500.93
8_H44_S0.5490.93
6_L46_Y0.5480.93
60_G66_P0.5470.93
52_F56_L0.5440.93
33_K75_K0.5350.92
35_Y42_Q0.5280.92
63_K75_K0.5270.92
49_L78_P0.5260.92
13_L43_L0.5220.91
10_F54_N0.5200.91
61_K66_P0.5160.91
39_L43_L0.5160.91
7_G10_F0.5090.90
61_K65_K0.5080.90
33_K79_L0.5060.90
54_N60_G0.5020.90
59_Y62_E0.5020.90
32_K71_Y0.5000.89
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4ykcA 1 0.5732 8 0.867 Contact Map
4j8sA 1 0.7439 6.8 0.871 Contact Map
4b8bA 2 1 6.3 0.873 Contact Map
4w5xB 1 0.7927 3.2 0.889 Contact Map
1x2iA 2 0.5 1.7 0.905 Contact Map
4offA 1 0.3049 1.7 0.905 Contact Map
2kvcA 1 0.7439 1.6 0.906 Contact Map
4tp8M 1 0.5732 1.5 0.908 Contact Map
1a1wA 1 0.6585 1.5 0.908 Contact Map
4kg1A 2 0.1341 1.4 0.909 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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