GREMLIN Database
Band_7_C - C-terminal region of band_7
PFAM: PF16200 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 63 (59)
Sequences: 8316 (3905)
Seq/√Len: 508.4
META: 0.892

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
7_I16_V3.1371.00
23_Q26_E3.1131.00
43_N46_D2.8221.00
5_E9_Q2.6151.00
27_A30_K2.5701.00
19_R22_E2.5291.00
13_V17_N2.2121.00
26_E29_G2.0971.00
56_E59_K1.9911.00
2_M5_E1.8831.00
30_K33_K1.7421.00
5_E8_A1.6001.00
33_K36_N1.4101.00
31_L39_I1.3711.00
23_Q27_A1.2721.00
40_L48_A1.2491.00
39_I52_A1.1731.00
37_T40_L1.1621.00
25_V47_V1.1191.00
8_A11_G1.0981.00
24_Y28_F1.0981.00
6_A9_Q1.0661.00
53_G56_E1.0601.00
55_M58_V1.0511.00
34_E37_T1.0411.00
8_A12_G1.0191.00
50_M54_A1.0021.00
22_E26_E0.9591.00
31_L38_L0.9531.00
28_F32_A0.9391.00
3_V19_R0.9331.00
48_A52_A0.9261.00
4_A12_G0.9261.00
31_L37_T0.9121.00
41_P49_G0.9051.00
47_V50_M0.8611.00
14_E17_N0.8431.00
35_S38_L0.8161.00
28_F42_A0.8111.00
49_G52_A0.8051.00
8_A14_E0.7971.00
48_A51_I0.7941.00
26_E30_K0.7941.00
30_K34_E0.7941.00
19_R23_Q0.7881.00
16_V58_V0.7871.00
16_V19_R0.7821.00
42_A50_M0.7661.00
44_L48_A0.7561.00
17_N58_V0.7551.00
51_I54_A0.7491.00
2_M9_Q0.7271.00
9_Q12_G0.7201.00
13_V60_A0.7171.00
33_K37_T0.7141.00
55_M59_K0.7081.00
23_Q29_G0.6721.00
56_E60_A0.6681.00
45_S48_A0.6671.00
31_L34_E0.6661.00
3_V6_A0.6511.00
35_S39_I0.6451.00
47_V51_I0.6431.00
44_L47_V0.6381.00
29_G33_K0.6211.00
28_F40_L0.6191.00
43_N49_G0.6191.00
39_I44_L0.6191.00
31_L40_L0.6161.00
20_V55_M0.6091.00
31_L35_S0.6081.00
17_N24_Y0.5970.99
24_Y44_L0.5880.99
11_G19_R0.5710.99
38_L56_E0.5700.99
8_A13_V0.5680.99
57_V60_A0.5610.99
9_Q13_V0.5480.99
44_L53_G0.5430.99
44_L50_M0.5390.99
2_M6_A0.5340.99
24_Y45_S0.5330.99
11_G15_A0.5140.98
50_M53_G0.5120.98
5_E10_P0.5100.98
52_A55_M0.5080.98
52_A57_V0.5050.98
43_N53_G0.5000.98
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4fccA 5 0.7937 10.7 0.851 Contact Map
3aoeE 3 0.7937 10.3 0.852 Contact Map
3mw9A 5 0.7937 10.1 0.853 Contact Map
3r3jA 5 0.7937 9.9 0.853 Contact Map
2bmaA 5 0.7937 9.3 0.855 Contact Map
3aogA 8 0.7937 9.3 0.855 Contact Map
1y4cA 1 0.5238 9.1 0.856 Contact Map
2yfqA 5 0.7937 9 0.856 Contact Map
1bgvA 5 0.7937 8.7 0.857 Contact Map
4xgiA 6 0.7302 8 0.86 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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