GREMLIN Database
NYD-SP28 - Sperm tail
PFAM: PF14772 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 101 (99)
Sequences: 633 (499)
Seq/√Len: 50.2
META: 0.427

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
6_E9_R3.3861.00
90_Y94_L3.0231.00
36_A40_M2.6121.00
70_D74_A2.4311.00
27_E42_W2.2241.00
57_E60_I2.2191.00
29_K33_K2.1681.00
55_R59_E2.1221.00
51_P55_R1.9951.00
3_D10_R1.9851.00
62_S66_E1.9520.99
22_E26_E1.7730.99
15_E19_E1.7520.99
34_N37_K1.7070.99
38_I72_K1.6220.98
27_E31_S1.5590.97
71_R74_A1.5570.97
43_R47_R1.5540.97
37_K40_M1.5110.97
33_K40_M1.4480.96
63_Q70_D1.4440.96
25_E29_K1.4440.96
4_A8_Q1.4430.96
60_I67_R1.4100.95
20_R79_L1.4080.95
91_V95_R1.4020.95
60_I63_Q1.3820.95
14_E17_R1.3550.94
88_E92_K1.3280.93
45_I68_I1.3190.93
73_D100_D1.3130.93
45_I54_L1.3020.93
8_Q12_K1.2630.91
34_N67_R1.2600.91
26_E30_S1.2370.91
73_D76_I1.2040.89
88_E95_R1.1810.88
65_C78_E1.1420.87
10_R13_E1.1300.86
12_K58_I1.1160.85
21_K88_E1.1150.85
61_Q65_C1.0940.84
27_E73_D1.0860.84
86_A89_Q1.0690.83
6_E13_E1.0670.83
15_E20_R1.0410.81
67_R70_D1.0290.80
63_Q67_R1.0270.80
59_E62_S1.0150.79
38_I65_C1.0110.79
7_E14_E1.0050.79
5_R19_E1.0050.79
46_L50_K1.0000.78
38_I68_I0.9960.78
60_I70_D0.9960.78
79_L97_H0.9820.77
68_I87_D0.9790.77
61_Q75_L0.9760.77
6_E14_E0.9570.75
19_E23_K0.9550.75
73_D84_K0.9470.75
74_A78_E0.9440.74
6_E10_R0.9420.74
28_A32_A0.9390.74
72_K76_I0.9380.74
95_R98_L0.9300.73
42_W82_E0.9250.73
87_D95_R0.8990.71
16_L20_R0.8920.70
60_I64_N0.8890.70
89_Q95_R0.8870.70
20_R25_E0.8830.69
7_E11_K0.8690.68
8_Q14_E0.8690.68
33_K58_I0.8600.67
66_E69_I0.8380.65
4_A12_K0.8380.65
48_K84_K0.8370.65
88_E94_L0.8350.65
51_P83_L0.8200.63
8_Q11_K0.8110.63
23_K26_E0.8070.62
3_D7_E0.8070.62
21_K24_L0.7790.59
10_R68_I0.7770.59
86_A91_V0.7730.59
38_I41_K0.7730.59
61_Q68_I0.7700.59
68_I78_E0.7680.58
4_A19_E0.7610.58
59_E88_E0.7580.57
30_S36_A0.7580.57
42_W97_H0.7390.55
89_Q97_H0.7380.55
55_R66_E0.7350.55
82_E92_K0.7200.54
67_R89_Q0.7180.53
24_L57_E0.7100.53
29_K38_I0.7070.52
25_E39_N0.7040.52
13_E86_A0.7010.52
82_E85_E0.6790.49
48_K52_Q0.6770.49
44_E68_I0.6730.49
52_Q56_K0.6680.48
48_K90_Y0.6590.47
41_K59_E0.6590.47
74_A77_Q0.6550.47
19_E101_I0.6550.47
12_K59_E0.6520.47
29_K32_A0.6390.45
30_S34_N0.6320.45
66_E77_Q0.6250.44
55_R87_D0.6160.43
12_K88_E0.6150.43
69_I79_L0.6070.42
88_E93_A0.5980.41
36_A39_N0.5960.41
51_P58_I0.5960.41
32_A36_A0.5950.41
37_K94_L0.5850.40
81_Q85_E0.5760.39
18_R25_E0.5760.39
31_S45_I0.5730.39
29_K58_I0.5730.39
3_D9_R0.5710.38
35_N45_I0.5650.38
28_A31_S0.5640.38
56_K60_I0.5630.38
65_C68_I0.5610.37
8_Q101_I0.5550.37
95_R99_E0.5530.37
84_K87_D0.5520.37
32_A60_I0.5470.36
64_N77_Q0.5450.36
93_A97_H0.5430.36
68_I72_K0.5380.35
15_E26_E0.5310.35
45_I79_L0.5310.35
56_K74_A0.5280.34
7_E85_E0.5260.34
49_A85_E0.5170.33
68_I71_R0.5160.33
17_R99_E0.5120.33
59_E77_Q0.5110.33
28_A43_R0.5080.33
21_K29_K0.5000.32
21_K25_E0.5000.32
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2dfsA 2 0.7624 6.9 0.88 Contact Map
3mq9A 4 0.9109 5.4 0.885 Contact Map
3ghgA 2 0.6535 3.9 0.893 Contact Map
1zxaA 1 0.3465 2.9 0.9 Contact Map
4hpqC 2 0.7129 2.8 0.9 Contact Map
4noxA 1 0 2 0.908 Contact Map
4ll8E 2 0.9307 1.9 0.909 Contact Map
4emcA 2 0.3465 1.9 0.909 Contact Map
3nmdA 2 0.4851 1.9 0.909 Contact Map
4jkvA 2 0.7129 1.7 0.911 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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