GREMLIN Database
Abi_C - Abortive infection C-terminus
PFAM: PF14355 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 83 (81)
Sequences: 5635 (3755)
Seq/√Len: 417.2
META: 0.914

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
46_R52_A3.4881.00
35_L73_A2.7511.00
30_R41_G2.5591.00
34_G41_G2.5321.00
26_E30_R2.4591.00
30_R40_Q2.3751.00
72_N76_T2.2451.00
6_E10_A1.9381.00
31_I41_G1.9231.00
34_G37_S1.8871.00
4_Y39_V1.8681.00
2_K6_E1.7061.00
40_Q44_E1.6851.00
5_K36_A1.6771.00
27_D44_E1.6701.00
4_Y8_A1.6681.00
63_S66_H1.6221.00
55_R59_N1.5291.00
26_E29_K1.5251.00
30_R33_G1.4731.00
30_R44_E1.4631.00
30_R37_S1.3801.00
73_A76_T1.3671.00
5_K16_S1.3421.00
35_L76_T1.3411.00
8_A36_A1.3281.00
35_L77_L1.2991.00
6_E9_K1.2971.00
29_K33_G1.2861.00
68_R79_T1.2761.00
70_A74_A1.2651.00
33_G37_S1.2451.00
24_G49_Y1.2371.00
5_K9_K1.2361.00
14_A17_Q1.1931.00
75_G79_T1.1881.00
25_E29_K1.1241.00
78_A82_L1.1131.00
42_L70_A1.0791.00
49_Y62_L1.0501.00
75_G78_A1.0411.00
44_E48_K1.0191.00
7_V10_A1.0031.00
13_L80_F0.9951.00
40_Q43_A0.9781.00
71_V75_G0.9771.00
64_P68_R0.9731.00
28_I66_H0.9511.00
37_S40_Q0.9171.00
72_N79_T0.9021.00
77_L81_L0.8961.00
34_G38_I0.8931.00
33_G36_A0.8911.00
27_D47_N0.8651.00
27_D34_G0.8581.00
36_A40_Q0.8351.00
9_K16_S0.8151.00
59_N62_L0.8011.00
69_L80_F0.7961.00
27_D41_G0.7921.00
62_L66_H0.7801.00
45_L70_A0.7791.00
19_P22_A0.7791.00
24_G48_K0.7771.00
38_I73_A0.7391.00
31_I70_A0.7361.00
7_V54_G0.7211.00
43_A47_N0.7211.00
75_G82_L0.7171.00
2_K47_N0.7141.00
72_N75_G0.7081.00
46_R53_H0.7041.00
30_R34_G0.6871.00
31_I34_G0.6690.99
60_P66_H0.6610.99
69_L73_A0.6570.99
7_V81_L0.6550.99
28_I45_L0.6520.99
18_H24_G0.6500.99
43_A48_K0.6460.99
2_K44_E0.6460.99
5_K33_G0.6430.99
31_I38_I0.6420.99
7_V11_L0.6390.99
68_R72_N0.6360.99
49_Y55_R0.6350.99
66_H80_F0.6340.99
36_A77_L0.6250.99
35_L38_I0.6210.99
2_K14_A0.6200.99
46_R50_G0.6150.99
66_H74_A0.6090.99
12_N17_Q0.6020.99
59_N82_L0.5980.99
8_A29_K0.5860.99
12_N16_S0.5810.99
4_Y77_L0.5750.98
58_R61_G0.5740.98
22_A28_I0.5720.98
44_E47_N0.5630.98
51_D75_G0.5620.98
17_Q21_G0.5610.98
56_G59_N0.5590.98
13_L18_H0.5580.98
76_T79_T0.5570.98
4_Y7_V0.5480.98
31_I69_L0.5480.98
56_G60_P0.5470.98
6_E11_L0.5470.98
41_G44_E0.5450.98
16_S57_G0.5430.98
69_L76_T0.5360.98
61_G66_H0.5330.98
55_R58_R0.5280.97
47_N53_H0.5250.97
21_G25_E0.5230.97
47_N52_A0.5100.97
3_L67_A0.5050.97
12_N18_H0.5050.97
18_H25_E0.5040.97
58_R62_L0.5000.96
17_Q26_E0.5000.96
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3qupA 1 0.4096 22.4 0.848 Contact Map
4anjA 1 0.8193 19.1 0.852 Contact Map
4byfA 1 0.8916 14.6 0.86 Contact Map
4pa0A 1 0.9277 13.6 0.862 Contact Map
4l79A 1 0.8916 9.9 0.87 Contact Map
1kk8A 1 0.9036 9.3 0.872 Contact Map
2dfsA 2 0.8795 9.1 0.872 Contact Map
3ljxA 1 0.241 8.9 0.873 Contact Map
1g8xA 2 0.9157 8.8 0.873 Contact Map
1w9iA 1 0.8434 8.7 0.873 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0044 seconds.