SprA_N - PFAM28P - GREMLIN Contacts

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SprA_N - Motility related/secretion protein

PFAM:	PF14349	Sequences: NYLNQLQAKLSSAAYQKALNDPSGDNYHYYRGSDYDAQEASILERYKNYNGPEGNSPTSEQSTESYPTSATTLPDVEDINRDNTLNETESYFQYKVSLRPGDMVVGQNYITDKREVTVTLPNGTTETVTWYQFRIPIREYEKKVGGISDFKSIRFMRMFLTGFEDPVVLRFATLELVRGEWRRYTQSLPNPEPDNTTFDVSAVNIEENSSRTPVNYVLPPGIEREQDPSNNQLIQQNEQSLSLKVCNLEDGDARAVYKNTNLDLRQYKRLKMFVHAESLTPLQDGDLTAFIRLGSDFTNNYYEYEIPLKLTPPGNNNSATDREEVWPEENELDIDLELLTDLKLERNRSGVSLNTPYSEYDGDPGNRITVKGNPNLGNVRTIMIGVRNDDGLPKSGEVWVNELRLSDFDEKGGWAANARLDANLADLGTVSASGSYSTAGFGSLEQKVNERSREDTYQYDVSTNLELGKFLPEKWGVSIPFYYSYSEEVITPKYDPLDPDIKLKDAL	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	507 (495)
Sequences:	4101 (2813)
Seq/√Len:	126.4
META:	0.885

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
246_C	395_S	5.450	1.00
269_R	333_D	4.397	1.00
28_H	34_D	4.297	1.00
113_K	129_T	4.096	1.00
285_G	309_K	4.030	1.00
384_I	400_V	3.979	1.00
345_E	359_E	3.799	1.00
97_S	102_D	3.591	1.00
93_Q	159_F	3.488	1.00
356_P	369_T	3.325	1.00
493_K	502_K	3.301	1.00
28_H	32_G	3.266	1.00
428_G	465_L	3.071	1.00
41_S	44_E	2.928	1.00
284_D	309_K	2.915	1.00
140_Y	143_K	2.896	1.00
309_K	329_E	2.893	1.00
335_D	338_L	2.887	1.00
342_L	368_I	2.872	1.00
268_K	407_D	2.817	1.00
240_S	401_N	2.699	1.00
115_E	127_T	2.673	1.00
274_V	289_A	2.541	1.00
40_A	44_E	2.530	1.00
287_L	396_G	2.493	1.00
104_V	107_Q	2.476	1.00
288_T	305_E	2.429	1.00
436_Y	457_Y	2.421	1.00
337_E	341_D	2.303	1.00
82_D	86_N	2.272	1.00
495_D	498_D	2.259	1.00
502_K	505_D	2.254	1.00
12_S	18_A	2.231	1.00
244_K	397_E	2.217	1.00
453_R	493_K	2.203	1.00
342_L	359_E	2.202	1.00
12_S	16_Q	2.195	1.00
99_R	102_D	2.192	1.00
358_S	369_T	2.187	1.00
340_T	501_I	2.097	1.00
215_N	325_V	2.076	1.00
92_F	149_D	2.070	1.00
467_L	481_F	2.043	1.00
439_A	455_D	2.028	1.00
115_E	129_T	2.027	1.00
158_M	174_L	2.017	1.00
411_K	493_K	1.998	1.00
321_D	324_E	1.997	1.00
10_L	18_A	1.990	1.00
28_H	35_Y	1.984	1.00
245_V	396_G	1.949	1.00
58_T	61_Q	1.948	1.00
12_S	15_Y	1.947	1.00
427_L	465_L	1.937	1.00
150_F	153_I	1.935	1.00
446_Q	450_E	1.926	1.00
271_K	331_E	1.914	1.00
463_T	483_Y	1.904	1.00
249_E	252_D	1.897	1.00
437_S	452_S	1.893	1.00
241_L	256_V	1.889	1.00
33_S	37_A	1.888	1.00
289_A	400_V	1.880	1.00
216_Y	219_P	1.874	1.00
274_V	332_L	1.869	1.00
24_G	48_N	1.862	1.00
200_V	256_V	1.861	1.00
15_Y	19_L	1.860	1.00
361_D	366_N	1.847	1.00
205_I	224_R	1.826	1.00
241_L	400_V	1.809	1.00
356_P	371_K	1.776	1.00
103_M	110_I	1.760	1.00
206_E	224_R	1.758	1.00
98_L	169_L	1.745	1.00
95_K	141_E	1.742	1.00
35_Y	40_A	1.717	1.00
13_A	17_K	1.713	1.00
16_Q	19_L	1.712	1.00
424_L	428_G	1.711	1.00
269_R	335_D	1.710	1.00
452_S	456_T	1.701	1.00
10_L	14_A	1.696	1.00
103_M	106_G	1.693	1.00
117_T	127_T	1.684	1.00
328_E	331_E	1.676	1.00
271_K	333_D	1.664	1.00
250_D	389_D	1.664	1.00
282_L	310_L	1.660	1.00
143_K	146_G	1.644	1.00
199_D	244_K	1.640	1.00
217_V	325_V	1.626	1.00
338_L	368_I	1.620	1.00
312_P	324_E	1.615	1.00
64_E	68_T	1.607	1.00
347_N	498_D	1.602	1.00
276_A	308_L	1.598	1.00
319_A	324_E	1.595	1.00
337_E	340_T	1.577	1.00
102_D	107_Q	1.573	1.00
432_A	461_V	1.570	1.00
289_A	332_L	1.567	1.00
96_V	135_I	1.565	1.00
27_Y	70_A	1.562	1.00
105_V	108_N	1.550	1.00
93_Q	142_K	1.544	1.00
160_L	169_L	1.537	1.00
205_I	218_L	1.533	1.00
306_I	332_L	1.532	1.00
323_E	328_E	1.528	1.00
120_L	123_G	1.526	1.00
390_D	394_K	1.525	1.00
435_S	458_Q	1.506	1.00
266_Q	409_D	1.502	1.00
338_L	361_D	1.501	1.00
33_S	64_E	1.488	1.00
242_S	397_E	1.483	1.00
443_S	446_Q	1.475	1.00
109_Y	139_E	1.466	1.00
310_L	313_P	1.463	1.00
299_N	371_K	1.454	1.00
15_Y	18_A	1.453	1.00
32_G	35_Y	1.444	1.00
211_R	214_V	1.439	1.00
105_V	113_K	1.438	1.00
32_G	36_D	1.420	1.00
103_M	108_N	1.411	1.00
26_N	53_E	1.398	1.00
227_D	234_I	1.395	1.00
119_T	125_T	1.384	1.00
264_L	379_V	1.378	1.00
289_A	308_L	1.378	1.00
360_Y	367_R	1.361	1.00
341_D	344_L	1.360	1.00
222_I	273_F	1.357	1.00
335_D	368_I	1.355	1.00
320_T	325_V	1.345	1.00
14_A	18_A	1.337	1.00
28_H	48_N	1.336	1.00
204_N	237_N	1.330	1.00
203_V	242_S	1.327	1.00
289_A	384_I	1.324	1.00
250_D	391_G	1.322	1.00
323_E	331_E	1.316	1.00
461_V	483_Y	1.313	1.00
436_Y	455_D	1.311	1.00
438_T	455_D	1.311	1.00
304_Y	366_N	1.306	1.00
28_H	40_A	1.296	1.00
466_E	478_S	1.291	1.00
319_A	322_R	1.290	1.00
278_S	310_L	1.289	1.00
276_A	310_L	1.287	1.00
434_G	457_Y	1.280	1.00
345_E	357_Y	1.280	1.00
32_G	40_A	1.278	1.00
287_L	394_K	1.272	1.00
160_L	167_V	1.270	1.00
102_D	106_G	1.265	1.00
422_A	430_V	1.262	1.00
291_I	332_L	1.261	1.00
117_T	125_T	1.255	1.00
250_D	390_D	1.255	1.00
171_F	174_L	1.252	1.00
305_E	367_R	1.252	1.00
214_V	311_T	1.246	1.00
264_L	405_L	1.244	1.00
319_A	325_V	1.237	1.00
342_L	370_V	1.231	0.99
247_N	395_S	1.228	0.99
288_T	389_D	1.219	0.99
332_L	366_N	1.217	0.99
495_D	506_A	1.217	0.99
303_E	387_R	1.210	0.99
13_A	16_Q	1.210	0.99
456_T	490_I	1.208	0.99
268_K	409_D	1.208	0.99
112_D	208_N	1.206	0.99
430_V	461_V	1.204	0.99
35_Y	48_N	1.204	0.99
184_Y	383_M	1.202	0.99
62_S	65_S	1.196	0.99
204_N	239_Q	1.188	0.99
21_D	26_N	1.179	0.99
134_R	199_D	1.176	0.99
498_D	506_A	1.174	0.99
293_L	379_V	1.172	0.99
198_F	243_L	1.169	0.99
437_S	454_E	1.167	0.99
344_L	501_I	1.158	0.99
427_L	469_K	1.155	0.99
196_T	254_R	1.152	0.99
284_D	310_L	1.150	0.99
120_L	126_E	1.147	0.99
467_L	470_F	1.146	0.99
245_V	386_V	1.146	0.99
36_D	40_A	1.138	0.99
431_S	462_S	1.137	0.99
102_D	105_V	1.134	0.99
10_L	15_Y	1.131	0.99
214_V	325_V	1.129	0.99
471_L	475_W	1.127	0.99
118_V	122_N	1.121	0.99
264_L	336_L	1.118	0.99
38_Q	44_E	1.116	0.99
457_Y	489_V	1.114	0.99
283_Q	286_D	1.114	0.99
48_N	51_G	1.109	0.99
278_S	281_P	1.109	0.99
270_L	403_L	1.109	0.99
211_R	242_S	1.108	0.99
358_S	367_R	1.105	0.99
32_G	64_E	1.103	0.99
305_E	387_R	1.102	0.99
345_E	348_R	1.098	0.99
10_L	13_A	1.093	0.99
466_E	469_K	1.092	0.99
224_R	235_Q	1.088	0.99
247_N	393_P	1.087	0.99
317_N	322_R	1.085	0.99
11_S	14_A	1.084	0.99
437_S	456_T	1.077	0.99
457_Y	491_T	1.074	0.99
34_D	40_A	1.069	0.99
269_R	407_D	1.068	0.99
205_I	237_N	1.066	0.99
266_Q	453_R	1.066	0.99
49_Y	70_A	1.060	0.98
211_R	277_E	1.060	0.98
273_F	331_E	1.060	0.98
285_G	329_E	1.057	0.98
134_R	201_S	1.056	0.98
472_P	475_W	1.050	0.98
50_N	55_N	1.050	0.98
20_N	26_N	1.045	0.98
16_Q	20_N	1.043	0.98
455_D	491_T	1.040	0.98
34_D	38_Q	1.030	0.98
342_L	345_E	1.027	0.98
101_G	104_V	1.024	0.98
347_N	373_N	1.023	0.98
93_Q	141_E	1.020	0.98
113_K	131_Y	1.017	0.98
221_G	273_F	1.017	0.98
211_R	397_E	1.008	0.98
90_S	146_G	1.008	0.98
243_L	256_V	1.005	0.98
226_Q	235_Q	1.005	0.98
311_T	319_A	1.001	0.98
458_Q	488_E	1.001	0.98
276_A	289_A	0.999	0.98
196_T	249_E	0.999	0.98
310_L	396_G	0.993	0.98
288_T	387_R	0.989	0.98
296_D	300_N	0.988	0.98
494_Y	502_K	0.986	0.98
211_R	216_Y	0.984	0.98
334_I	339_L	0.984	0.98
432_A	459_Y	0.983	0.98
188_L	252_D	0.980	0.97
120_L	124_T	0.979	0.97
338_L	341_D	0.976	0.97
253_A	290_F	0.970	0.97
28_H	33_S	0.967	0.97
352_S	355_T	0.963	0.97
293_L	376_L	0.963	0.97
361_D	364_P	0.960	0.97
63_T	66_Y	0.950	0.97
311_T	314_G	0.941	0.97
61_Q	64_E	0.939	0.97
58_T	67_P	0.934	0.97
58_T	62_S	0.932	0.97
80_N	154_R	0.931	0.97
491_T	503_L	0.930	0.97
204_N	207_E	0.926	0.96
107_Q	110_I	0.923	0.96
449_N	453_R	0.920	0.96
11_S	18_A	0.920	0.96
246_C	279_L	0.918	0.96
351_V	355_T	0.916	0.96
418_A	434_G	0.911	0.96
362_G	365_G	0.910	0.96
359_E	362_G	0.910	0.96
311_T	325_V	0.909	0.96
501_I	506_A	0.909	0.96
363_D	366_N	0.908	0.96
95_K	162_G	0.904	0.96
14_A	17_K	0.903	0.96
290_F	387_R	0.903	0.96
344_L	348_R	0.900	0.96
342_L	369_T	0.899	0.96
17_K	48_N	0.896	0.96
274_V	400_V	0.896	0.96
23_S	52_P	0.895	0.96
11_S	15_Y	0.893	0.96
459_Y	487_E	0.892	0.96
377_G	499_P	0.890	0.96
43_L	168_V	0.888	0.95
63_T	67_P	0.888	0.95
375_N	499_P	0.886	0.95
266_Q	493_K	0.880	0.95
465_L	481_F	0.880	0.95
278_S	313_P	0.878	0.95
147_I	150_F	0.876	0.95
318_S	321_D	0.875	0.95
286_D	289_A	0.875	0.95
196_T	252_D	0.868	0.95
468_G	477_V	0.867	0.95
414_W	436_Y	0.862	0.95
143_K	147_I	0.861	0.95
253_A	387_R	0.861	0.95
34_D	37_A	0.859	0.95
272_M	403_L	0.858	0.95
33_S	65_S	0.856	0.94
18_A	24_G	0.854	0.94
459_Y	489_V	0.852	0.94
255_A	383_M	0.852	0.94
243_L	400_V	0.849	0.94
306_I	366_N	0.844	0.94
228_P	232_Q	0.843	0.94
96_V	133_F	0.843	0.94
60_E	64_E	0.842	0.94
433_S	460_D	0.840	0.94
99_R	103_M	0.840	0.94
466_E	479_I	0.838	0.94
118_V	126_E	0.837	0.94
214_V	313_P	0.837	0.94
104_V	113_K	0.833	0.94
78_D	82_D	0.832	0.94
111_T	201_S	0.829	0.94
439_A	493_K	0.829	0.94
321_D	325_V	0.825	0.93
331_E	334_I	0.819	0.93
109_Y	141_E	0.817	0.93
341_D	345_E	0.816	0.93
273_F	404_R	0.815	0.93
90_S	143_K	0.813	0.93
156_M	176_L	0.811	0.93
52_P	55_N	0.808	0.93
134_R	242_S	0.805	0.92
13_A	18_A	0.804	0.92
279_L	395_S	0.804	0.92
205_I	217_V	0.798	0.92
469_K	473_E	0.798	0.92
10_L	16_Q	0.794	0.92
52_P	75_D	0.794	0.92
189_P	192_E	0.792	0.92
250_D	393_P	0.792	0.92
57_P	63_T	0.791	0.92
97_S	101_G	0.791	0.92
183_R	198_F	0.788	0.92
58_T	64_E	0.787	0.92
419_R	460_D	0.786	0.92
31_R	64_E	0.786	0.92
341_D	505_D	0.784	0.91
268_K	337_E	0.783	0.91
304_Y	332_L	0.782	0.91
12_S	17_K	0.780	0.91
466_E	475_W	0.778	0.91
290_F	385_G	0.777	0.91
270_L	293_L	0.777	0.91
462_S	482_Y	0.776	0.91
51_G	55_N	0.775	0.91
44_E	48_N	0.774	0.91
140_Y	150_F	0.773	0.91
217_V	322_R	0.773	0.91
418_A	422_A	0.772	0.91
122_N	126_E	0.770	0.91
270_L	291_I	0.770	0.91
311_T	320_T	0.766	0.91
471_L	477_V	0.764	0.90
215_N	319_A	0.763	0.90
106_G	110_I	0.762	0.90
227_D	231_N	0.761	0.90
459_Y	485_Y	0.760	0.90
426_D	469_K	0.759	0.90
225_E	236_Q	0.756	0.90
390_D	393_P	0.756	0.90
278_S	282_L	0.754	0.90
57_P	61_Q	0.754	0.90
358_S	361_D	0.753	0.90
332_L	338_L	0.751	0.90
416_A	436_Y	0.750	0.90
349_S	355_T	0.750	0.90
103_M	107_Q	0.748	0.89
115_E	118_V	0.747	0.89
454_E	490_I	0.746	0.89
158_M	171_F	0.745	0.89
427_L	471_L	0.745	0.89
254_R	257_Y	0.744	0.89
21_D	25_D	0.744	0.89
97_S	108_N	0.743	0.89
271_K	406_S	0.742	0.89
442_G	451_R	0.741	0.89
250_D	392_L	0.739	0.89
211_R	313_P	0.739	0.89
129_T	132_Q	0.738	0.89
65_S	68_T	0.737	0.89
12_S	19_L	0.737	0.89
424_L	430_V	0.737	0.89
60_E	63_T	0.735	0.89
22_P	25_D	0.732	0.88
27_Y	68_T	0.732	0.88
27_Y	67_P	0.731	0.88
445_E	448_V	0.731	0.88
260_T	382_I	0.731	0.88
216_Y	220_P	0.730	0.88
322_R	325_V	0.730	0.88
419_R	431_S	0.728	0.88
61_Q	65_S	0.725	0.88
498_D	501_I	0.725	0.88
102_D	108_N	0.721	0.88
119_T	122_N	0.721	0.88
389_D	394_K	0.719	0.88
17_K	20_N	0.719	0.88
427_L	467_L	0.718	0.87
320_T	324_E	0.717	0.87
386_V	398_V	0.717	0.87
33_S	68_T	0.716	0.87
35_Y	38_Q	0.715	0.87
421_D	431_S	0.715	0.87
427_L	470_F	0.714	0.87
427_L	505_D	0.711	0.87
84_T	87_E	0.711	0.87
303_E	307_P	0.710	0.87
447_K	450_E	0.708	0.87
80_N	86_N	0.707	0.87
194_D	249_E	0.707	0.87
83_N	154_R	0.705	0.87
60_E	65_S	0.703	0.86
336_L	340_T	0.702	0.86
227_D	232_Q	0.701	0.86
64_E	67_P	0.701	0.86
175_E	375_N	0.700	0.86
94_Y	150_F	0.698	0.86
20_N	39_E	0.696	0.86
89_E	93_Q	0.696	0.86
111_T	134_R	0.693	0.86
225_E	234_I	0.693	0.86
215_N	218_L	0.691	0.85
132_Q	201_S	0.690	0.85
332_L	335_D	0.690	0.85
82_D	154_R	0.690	0.85
327_P	330_N	0.689	0.85
134_R	204_N	0.688	0.85
201_S	244_K	0.688	0.85
33_S	63_T	0.688	0.85
429_T	464_N	0.687	0.85
49_Y	257_Y	0.687	0.85
476_G	479_I	0.686	0.85
201_S	242_S	0.686	0.85
160_L	171_F	0.685	0.85
272_M	384_I	0.684	0.85
330_N	343_K	0.683	0.85
287_L	398_V	0.681	0.85
114_R	118_V	0.680	0.85
244_K	279_L	0.679	0.84
301_Y	369_T	0.679	0.84
31_R	36_D	0.679	0.84
501_I	505_D	0.676	0.84
199_D	246_C	0.675	0.84
31_R	66_Y	0.674	0.84
33_S	36_D	0.673	0.84
51_G	70_A	0.672	0.84
256_V	400_V	0.670	0.84
223_E	322_R	0.669	0.84
338_L	362_G	0.668	0.83
386_V	394_K	0.668	0.83
266_Q	449_N	0.667	0.83
62_S	68_T	0.666	0.83
439_A	499_P	0.663	0.83
106_G	109_Y	0.663	0.83
117_T	120_L	0.662	0.83
209_S	217_V	0.661	0.83
389_D	392_L	0.660	0.83
295_S	378_N	0.660	0.83
439_A	453_R	0.660	0.83
349_S	353_L	0.659	0.83
293_L	339_L	0.657	0.82
118_V	125_T	0.656	0.82
216_Y	221_G	0.656	0.82
10_L	17_K	0.655	0.82
187_S	249_E	0.655	0.82
290_F	383_M	0.653	0.82
192_E	247_N	0.653	0.82
202_A	239_Q	0.652	0.82
92_F	148_S	0.652	0.82
97_S	162_G	0.652	0.82
227_D	236_Q	0.651	0.82
340_T	502_K	0.649	0.82
356_P	359_E	0.649	0.82
318_S	322_R	0.647	0.81
317_N	321_D	0.647	0.81
190_N	193_P	0.646	0.81
11_S	16_Q	0.644	0.81
58_T	68_T	0.642	0.81
266_Q	494_Y	0.641	0.81
197_T	246_C	0.641	0.81
334_I	338_L	0.640	0.81
361_D	365_G	0.639	0.81
499_P	502_K	0.638	0.81
27_Y	63_T	0.636	0.80
55_N	59_S	0.635	0.80
292_R	303_E	0.634	0.80
119_T	124_T	0.633	0.80
255_A	297_F	0.633	0.80
456_T	488_E	0.632	0.80
31_R	68_T	0.632	0.80
135_I	171_F	0.631	0.80
33_S	66_Y	0.630	0.80
149_D	152_S	0.630	0.80
105_V	212_T	0.630	0.80
293_L	382_I	0.628	0.80
199_D	202_A	0.628	0.80
423_N	431_S	0.625	0.79
143_K	148_S	0.625	0.79
133_F	174_L	0.624	0.79
24_G	51_G	0.624	0.79
324_E	327_P	0.623	0.79
113_K	116_V	0.623	0.79
50_N	54_G	0.622	0.79
292_R	296_D	0.621	0.79
317_N	325_V	0.621	0.79
122_N	125_T	0.621	0.79
55_N	58_T	0.621	0.79
225_E	232_Q	0.619	0.79
428_G	466_E	0.618	0.78
428_G	483_Y	0.618	0.78
91_Y	240_S	0.617	0.78
257_Y	494_Y	0.617	0.78
342_L	358_S	0.617	0.78
163_F	167_V	0.616	0.78
312_P	319_A	0.616	0.78
338_L	366_N	0.616	0.78
62_S	66_Y	0.616	0.78
280_T	313_P	0.616	0.78
59_S	62_S	0.616	0.78
301_Y	307_P	0.616	0.78
419_R	435_S	0.615	0.78
411_K	439_A	0.615	0.78
350_G	359_E	0.614	0.78
338_L	342_L	0.614	0.78
452_S	464_N	0.612	0.78
206_E	237_N	0.611	0.78
249_E	393_P	0.611	0.78
28_H	36_D	0.611	0.78
291_I	403_L	0.610	0.78
158_M	161_T	0.610	0.78
218_L	222_I	0.608	0.77
19_L	24_G	0.608	0.77
349_S	352_S	0.605	0.77
297_F	383_M	0.604	0.77
119_T	123_G	0.603	0.77
58_T	63_T	0.600	0.76
430_V	465_L	0.599	0.76
204_N	213_P	0.599	0.76
288_T	367_R	0.599	0.76
468_G	478_S	0.599	0.76
280_T	283_Q	0.598	0.76
287_L	308_L	0.598	0.76
114_R	210_S	0.596	0.76
297_F	381_T	0.595	0.76
337_E	505_D	0.595	0.76
139_E	143_K	0.595	0.76
436_Y	452_S	0.594	0.76
14_A	24_G	0.594	0.76
57_P	70_A	0.594	0.76
109_Y	112_D	0.593	0.76
232_Q	236_Q	0.592	0.75
384_I	387_R	0.592	0.75
144_V	147_I	0.592	0.75
326_W	329_E	0.591	0.75
139_E	142_K	0.590	0.75
492_P	496_P	0.589	0.75
179_G	225_E	0.589	0.75
118_V	121_P	0.589	0.75
44_E	165_D	0.588	0.75
26_N	48_N	0.588	0.75
396_G	400_V	0.588	0.75
116_V	128_V	0.587	0.75
137_I	140_Y	0.587	0.75
53_E	56_S	0.586	0.75
249_E	504_K	0.586	0.75
110_I	133_F	0.585	0.75
452_S	455_D	0.585	0.75
419_R	433_S	0.582	0.74
184_Y	257_Y	0.580	0.74
190_N	194_D	0.579	0.74
63_T	68_T	0.577	0.74
352_S	357_Y	0.577	0.74
54_G	70_A	0.577	0.74
459_Y	467_L	0.577	0.74
255_A	381_T	0.576	0.73
100_P	103_M	0.576	0.73
183_R	200_V	0.575	0.73
95_K	99_R	0.575	0.73
336_L	376_L	0.575	0.73
399_W	402_E	0.575	0.73
27_Y	57_P	0.574	0.73
231_N	234_I	0.573	0.73
99_R	133_F	0.573	0.73
432_A	436_Y	0.573	0.73
208_N	213_P	0.572	0.73
211_R	215_N	0.571	0.73
57_P	60_E	0.570	0.73
140_Y	144_V	0.570	0.73
27_Y	48_N	0.568	0.72
336_L	501_I	0.568	0.72
134_R	366_N	0.567	0.72
187_S	194_D	0.567	0.72
195_N	422_A	0.567	0.72
413_G	438_T	0.566	0.72
58_T	66_Y	0.565	0.72
105_V	112_D	0.565	0.72
418_A	436_Y	0.564	0.72
259_N	381_T	0.564	0.72
154_R	259_N	0.563	0.72
438_T	442_G	0.563	0.72
475_W	479_I	0.562	0.72
31_R	62_S	0.562	0.72
339_L	368_I	0.562	0.72
447_K	453_R	0.561	0.72
104_V	108_N	0.560	0.71
468_G	471_L	0.560	0.71
264_L	376_L	0.559	0.71
495_D	501_I	0.557	0.71
270_L	334_I	0.556	0.71
475_W	478_S	0.555	0.71
20_N	48_N	0.554	0.71
282_L	396_G	0.554	0.71
367_R	371_K	0.554	0.71
244_K	395_S	0.554	0.71
276_A	287_L	0.553	0.70
345_E	349_S	0.552	0.70
244_K	386_V	0.552	0.70
32_G	38_Q	0.552	0.70
27_Y	395_S	0.552	0.70
51_G	405_L	0.552	0.70
137_I	183_R	0.550	0.70
340_T	505_D	0.549	0.70
80_N	85_L	0.548	0.70
206_E	267_Y	0.547	0.70
274_V	366_N	0.547	0.70
62_S	67_P	0.547	0.70
228_P	233_L	0.546	0.69
286_D	310_L	0.546	0.69
148_S	151_K	0.544	0.69
401_N	460_D	0.544	0.69
118_V	127_T	0.544	0.69
170_R	182_R	0.544	0.69
314_G	321_D	0.544	0.69
218_L	240_S	0.543	0.69
112_D	134_R	0.543	0.69
170_R	440_G	0.543	0.69
188_L	204_N	0.541	0.69
497_L	506_A	0.540	0.69
145_G	148_S	0.540	0.69
465_L	483_Y	0.540	0.69
137_I	367_R	0.539	0.68
110_I	131_Y	0.539	0.68
192_E	249_E	0.538	0.68
97_S	103_M	0.537	0.68
302_Y	307_P	0.536	0.68
14_A	19_L	0.536	0.68
482_Y	498_D	0.535	0.68
31_R	43_L	0.535	0.68
338_L	363_D	0.532	0.67
138_R	185_T	0.531	0.67
175_E	230_N	0.531	0.67
464_N	468_G	0.530	0.67
103_M	133_F	0.530	0.67
470_F	473_E	0.530	0.67
198_F	246_C	0.530	0.67
356_P	362_G	0.529	0.67
219_P	222_I	0.528	0.67
291_I	382_I	0.528	0.67
282_L	286_D	0.527	0.67
116_V	126_E	0.527	0.67
245_V	248_L	0.526	0.67
439_A	452_S	0.526	0.67
85_L	231_N	0.526	0.67
108_N	111_T	0.526	0.67
251_G	390_D	0.525	0.66
257_Y	304_Y	0.525	0.66
215_N	311_T	0.525	0.66
212_T	323_E	0.524	0.66
49_Y	52_P	0.524	0.66
61_Q	66_Y	0.524	0.66
175_E	444_L	0.523	0.66
77_E	80_N	0.522	0.66
301_Y	371_K	0.522	0.66
163_F	483_Y	0.522	0.66
256_V	503_L	0.522	0.66
134_R	222_I	0.521	0.66
95_K	142_K	0.520	0.66
332_L	398_V	0.520	0.66
226_Q	233_L	0.520	0.66
466_E	471_L	0.519	0.66
19_L	48_N	0.519	0.66
227_D	230_N	0.518	0.65
57_P	68_T	0.518	0.65
344_L	503_L	0.517	0.65
62_S	70_A	0.517	0.65
188_L	254_R	0.516	0.65
435_S	456_T	0.516	0.65
14_A	51_G	0.516	0.65
417_N	422_A	0.515	0.65
92_F	138_R	0.514	0.65
29_Y	58_T	0.513	0.65
175_E	264_L	0.512	0.65
373_N	498_D	0.512	0.65
453_R	494_Y	0.512	0.65
265_R	377_G	0.512	0.65
422_A	428_G	0.511	0.64
71_T	75_D	0.511	0.64
29_Y	32_G	0.511	0.64
85_L	468_G	0.510	0.64
121_P	124_T	0.510	0.64
431_S	495_D	0.509	0.64
461_V	464_N	0.508	0.64
170_R	442_G	0.508	0.64
82_D	87_E	0.507	0.64
92_F	153_I	0.507	0.64
314_G	320_T	0.506	0.64
198_F	249_E	0.506	0.64
178_R	265_R	0.506	0.64
421_D	429_T	0.505	0.64
101_G	107_Q	0.504	0.63
146_G	149_D	0.503	0.63
377_G	502_K	0.503	0.63
176_L	491_T	0.503	0.63
344_L	505_D	0.503	0.63
338_L	501_I	0.502	0.63
147_I	152_S	0.502	0.63
101_G	106_G	0.502	0.63
295_S	377_G	0.502	0.63
135_I	194_D	0.502	0.63
461_V	485_Y	0.502	0.63
61_Q	68_T	0.501	0.63
16_Q	38_Q	0.501	0.63
267_Y	449_N	0.500	0.63
34_D	66_Y	0.500	0.63

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
1v0aA	1	0.3215	94.6	0.96	Contact Map
1wmxA	2	0.3452	67.7	0.972	Contact Map
1pmhX	1	0.3314	30.3	0.978	Contact Map
1fr2A	1	0.1124	19.5	0.98	Contact Map
1gxgA	1	0.1144	8.6	0.983	Contact Map
1unkA	4	0.1144	7.7	0.983	Contact Map
2k0dX	1	0.1144	6.5	0.984	Contact Map
1oh4A	1	0.3314	5.8	0.984	Contact Map
3u43A	1	0.1302	5.6	0.984	Contact Map
1ytrA	1	0.0513	5.4	0.984	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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