GREMLIN Database
PilX_N - PilX N-terminal
PFAM: PF14341 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 51 (50)
Sequences: 14628 (9635)
Seq/√Len: 1362.6
META: 0.949

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
37_R41_Q2.4461.00
16_T20_V2.3631.00
36_Y40_Q2.3091.00
3_A7_V2.2781.00
38_D41_Q1.9861.00
23_M27_T1.8401.00
38_D42_A1.6731.00
24_R27_T1.6041.00
30_E34_G1.5731.00
36_Y39_R1.5191.00
28_L32_M1.4511.00
34_G38_D1.4211.00
25_T28_L1.3801.00
30_E37_R1.3691.00
28_L35_N1.3431.00
41_Q45_A1.3431.00
40_Q44_Y1.3221.00
11_L15_L1.1961.00
39_R43_F1.1741.00
3_A6_V1.1681.00
20_V23_M1.1541.00
13_L16_T1.1211.00
39_R42_A1.1111.00
27_T31_R1.1021.00
9_L13_L1.0971.00
34_G37_R1.0911.00
25_T29_E1.0621.00
12_L16_T1.0491.00
6_V9_L1.0261.00
8_A12_L1.0011.00
5_L9_L0.9901.00
29_E36_Y0.9711.00
29_E32_M0.9641.00
42_A45_A0.9571.00
43_F47_E0.9411.00
19_G23_M0.9351.00
40_Q43_F0.9111.00
42_A46_A0.8611.00
21_A24_R0.8401.00
27_T30_E0.8331.00
4_A8_A0.8041.00
32_M35_N0.8001.00
46_A49_G0.7701.00
6_V10_L0.7661.00
24_R28_L0.7601.00
9_L12_L0.7591.00
41_Q44_Y0.7441.00
4_A7_V0.7351.00
20_V24_R0.7001.00
7_V11_L0.6961.00
21_A25_T0.6681.00
5_L33_A0.6661.00
47_E50_L0.6661.00
33_A36_Y0.6621.00
15_L22_A0.6541.00
23_M26_S0.6431.00
11_L14_V0.6411.00
17_L25_T0.6391.00
11_L32_M0.6391.00
42_A50_L0.6201.00
17_L21_A0.6111.00
37_R40_Q0.6061.00
4_A42_A0.5931.00
22_A26_S0.5761.00
12_L15_L0.5501.00
37_R47_E0.5461.00
31_R34_G0.5461.00
43_F48_A0.5401.00
10_L14_V0.5341.00
12_L19_G0.5301.00
19_G48_A0.5271.00
33_A47_E0.5161.00
2_G5_L0.5131.00
2_G8_A0.5041.00
18_L21_A0.5001.00
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4c7rA 3 1 16 0.756 Contact Map
3ci0K 1 0.4118 15.5 0.757 Contact Map
1oqwA 1 0.9608 3.5 0.821 Contact Map
2hi2A 1 0.8627 3.1 0.825 Contact Map
4ut1A 1 0 2.7 0.831 Contact Map
4gdxA 1 0.4706 2.3 0.837 Contact Map
3sokA 1 0.8824 2.2 0.839 Contact Map
3whrA 1 0.4314 2.1 0.84 Contact Map
3j0fE 4 0.451 1.8 0.845 Contact Map
4he8J 1 0.5294 1.8 0.846 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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