DnaJ-X - PFAM28P - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

DnaJ-X - X-domain of DnaJ-containing

PFAM:	PF14308	Sequences: QKERVEKLAEKLKDRLSPYVEGDKGGVTEAFREKARLEAEDLKMESFGVELLHTIGYVYVRKAAQFLGSQKFLGVGGFFSRVKDKGHVVKSTVSTASSAIDAQQTMEEMAKAEEKGEGAEGEELTEEELAELEEEVTGKILEALWKGNKFDIESTLREVCDKVLKDKSVSKEKRKLRAKALKILGEIFQKAKRDEEEEEEAREFEELV	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	208 (196)
Sequences:	715 (485)
Seq/√Len:	34.6
META:	0.266

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
56_G	185_G	5.174	1.00
9_A	162_K	4.628	1.00
16_L	180_A	4.058	1.00
63_A	182_K	3.917	1.00
17_S	21_E	3.491	1.00
35_A	184_L	3.164	1.00
51_L	152_I	3.078	1.00
164_L	181_L	2.843	1.00
169_V	174_R	2.808	1.00
8_L	159_V	2.754	1.00
16_L	181_L	2.726	1.00
57_Y	87_H	2.691	1.00
48_G	145_W	2.652	1.00
15_R	38_E	2.589	1.00
5_V	158_E	2.576	1.00
33_E	36_R	2.511	1.00
87_H	153_E	2.451	1.00
55_I	156_L	2.449	1.00
39_A	187_I	2.375	0.99
1_Q	155_T	2.327	0.99
27_V	30_A	2.196	0.99
40_E	43_K	2.141	0.99
2_K	6_E	2.030	0.98
1_Q	5_V	2.016	0.98
42_L	59_Y	1.984	0.98
39_A	188_F	1.936	0.98
67_L	178_A	1.926	0.98
8_L	59_Y	1.867	0.97
4_R	155_T	1.819	0.97
29_E	33_E	1.761	0.96
82_V	85_K	1.733	0.96
67_L	175_K	1.727	0.95
163_V	177_R	1.711	0.95
51_L	59_Y	1.688	0.95
66_F	188_F	1.665	0.94
170_S	173_K	1.644	0.94
71_K	76_G	1.626	0.94
42_L	187_I	1.598	0.93
13_K	16_L	1.591	0.93
6_E	10_E	1.586	0.93
6_E	9_A	1.533	0.92
5_V	155_T	1.506	0.91
31_F	35_A	1.466	0.90
14_D	17_S	1.452	0.89
127_E	130_A	1.448	0.89
92_T	95_T	1.440	0.89
166_D	174_R	1.434	0.89
55_I	86_G	1.425	0.88
56_G	177_R	1.421	0.88
170_S	176_L	1.376	0.86
20_V	173_K	1.366	0.86
53_H	163_V	1.363	0.86
177_R	185_G	1.359	0.86
3_E	7_K	1.351	0.85
60_V	186_E	1.339	0.85
42_L	51_L	1.326	0.84
48_G	149_K	1.316	0.84
21_E	173_K	1.312	0.84
19_Y	28_T	1.259	0.81
109_M	132_L	1.259	0.81
7_K	47_F	1.251	0.81
31_F	145_W	1.196	0.77
39_A	65_Q	1.196	0.77
141_L	160_C	1.182	0.77
110_A	114_E	1.170	0.76
143_A	147_G	1.169	0.76
75_V	78_F	1.166	0.76
31_F	52_L	1.157	0.75
1_Q	4_R	1.130	0.73
112_A	116_G	1.126	0.73
49_V	53_H	1.125	0.73
195_E	198_E	1.121	0.73
92_T	154_S	1.119	0.73
151_D	155_T	1.074	0.69
193_R	197_E	1.067	0.69
31_F	160_C	1.039	0.67
95_T	99_A	1.034	0.66
128_E	131_E	1.023	0.66
110_A	113_E	1.022	0.66
36_R	190_K	1.014	0.65
13_K	163_V	1.009	0.64
39_A	132_L	1.009	0.64
9_A	13_K	1.006	0.64
9_A	83_K	1.006	0.64
32_R	186_E	0.998	0.64
24_K	176_L	0.996	0.63
87_H	93_V	0.981	0.62
4_R	56_G	0.971	0.61
148_N	152_I	0.966	0.61
137_T	140_I	0.962	0.61
46_S	133_E	0.960	0.61
36_R	170_S	0.958	0.60
58_V	153_E	0.949	0.60
18_P	22_G	0.948	0.60
17_S	20_V	0.939	0.59
89_V	96_A	0.929	0.58
159_V	163_V	0.923	0.58
10_E	14_D	0.921	0.57
5_V	149_K	0.917	0.57
65_Q	80_S	0.911	0.57
64_A	98_S	0.910	0.56
54_T	188_F	0.910	0.56
94_S	146_K	0.909	0.56
153_E	181_L	0.909	0.56
20_V	27_V	0.908	0.56
16_L	42_L	0.906	0.56
5_V	9_A	0.904	0.56
179_K	183_I	0.903	0.56
18_P	21_E	0.895	0.55
82_V	86_G	0.895	0.55
156_L	160_C	0.867	0.53
61_R	94_S	0.866	0.53
90_K	106_M	0.860	0.52
33_E	60_V	0.857	0.52
79_F	184_L	0.855	0.52
194_D	197_E	0.841	0.51
78_F	82_V	0.823	0.49
64_A	182_K	0.821	0.49
58_V	105_T	0.821	0.49
152_I	200_E	0.818	0.49
23_D	26_G	0.814	0.48
43_K	52_L	0.808	0.48
193_R	196_E	0.807	0.48
145_W	149_K	0.806	0.48
67_L	155_T	0.806	0.48
11_K	15_R	0.803	0.47
43_K	149_K	0.802	0.47
52_L	180_A	0.793	0.46
62_K	164_L	0.792	0.46
190_K	195_E	0.791	0.46
103_Q	148_N	0.790	0.46
186_E	189_Q	0.790	0.46
8_L	151_D	0.785	0.46
152_I	180_A	0.785	0.46
103_Q	107_E	0.778	0.45
3_E	155_T	0.775	0.45
8_L	51_L	0.772	0.45
66_F	178_A	0.770	0.45
50_E	74_G	0.765	0.44
51_L	155_T	0.762	0.44
6_E	162_K	0.761	0.44
162_K	171_K	0.755	0.43
92_T	106_M	0.752	0.43
133_E	143_A	0.752	0.43
122_E	188_F	0.751	0.43
82_V	156_L	0.751	0.43
130_A	133_E	0.748	0.43
4_R	177_R	0.745	0.42
33_E	37_L	0.742	0.42
116_G	121_G	0.737	0.42
60_V	162_K	0.735	0.42
133_E	147_G	0.728	0.41
131_E	169_V	0.726	0.41
21_E	54_T	0.723	0.41
104_Q	174_R	0.723	0.41
49_V	197_E	0.722	0.41
83_K	86_G	0.721	0.40
54_T	141_L	0.719	0.40
108_E	116_G	0.716	0.40
19_Y	93_V	0.715	0.40
111_K	115_K	0.714	0.40
2_K	143_A	0.710	0.40
39_A	191_A	0.705	0.39
70_Q	153_E	0.704	0.39
105_T	152_I	0.704	0.39
166_D	177_R	0.702	0.39
69_S	158_E	0.702	0.39
14_D	96_A	0.700	0.39
136_V	140_I	0.697	0.39
173_K	176_L	0.694	0.38
86_G	145_W	0.690	0.38
113_E	116_G	0.689	0.38
10_E	22_G	0.688	0.38
43_K	49_V	0.687	0.38
4_R	180_A	0.682	0.37
11_K	63_A	0.678	0.37
26_G	169_V	0.677	0.37
59_Y	164_L	0.676	0.37
166_D	170_S	0.676	0.37
42_L	164_L	0.672	0.37
113_E	162_K	0.668	0.36
88_V	150_F	0.668	0.36
168_S	183_I	0.666	0.36
16_L	164_L	0.665	0.36
2_K	169_V	0.663	0.36
68_G	76_G	0.660	0.36
137_T	153_E	0.658	0.35
126_E	130_A	0.656	0.35
107_E	110_A	0.654	0.35
10_E	13_K	0.653	0.35
51_L	148_N	0.652	0.35
58_V	87_H	0.645	0.34
171_K	180_A	0.644	0.34
51_L	54_T	0.643	0.34
62_K	159_V	0.641	0.34
68_G	189_Q	0.638	0.34
42_L	148_N	0.634	0.34
16_L	36_R	0.633	0.33
169_V	175_K	0.632	0.33
106_M	136_V	0.627	0.33
53_H	164_L	0.627	0.33
47_F	188_F	0.627	0.33
145_W	148_N	0.625	0.33
26_G	176_L	0.624	0.33
13_K	177_R	0.621	0.33
191_A	200_E	0.620	0.32
81_R	111_K	0.612	0.32
94_S	99_A	0.611	0.32
113_E	129_L	0.608	0.32
98_S	106_M	0.605	0.31
14_D	19_Y	0.601	0.31
144_L	148_N	0.599	0.31
9_A	196_E	0.599	0.31
37_L	154_S	0.598	0.31
8_L	61_R	0.597	0.31
62_K	149_K	0.594	0.31
8_L	11_K	0.592	0.30
17_S	141_L	0.591	0.30
46_S	66_F	0.589	0.30
22_G	151_D	0.588	0.30
43_K	151_D	0.588	0.30
112_A	115_K	0.586	0.30
101_D	154_S	0.586	0.30
42_L	144_L	0.585	0.30
31_F	62_K	0.583	0.30
147_G	151_D	0.580	0.30
84_D	90_K	0.579	0.30
182_K	195_E	0.576	0.29
60_V	171_K	0.576	0.29
69_S	81_R	0.574	0.29
179_K	188_F	0.574	0.29
157_R	161_D	0.573	0.29
98_S	102_A	0.571	0.29
111_K	114_E	0.568	0.29
133_E	136_V	0.567	0.29
17_S	27_V	0.563	0.28
175_K	180_A	0.563	0.28
42_L	153_E	0.563	0.28
32_R	36_R	0.563	0.28
23_D	27_V	0.561	0.28
22_G	26_G	0.560	0.28
160_C	181_L	0.559	0.28
42_L	62_K	0.559	0.28
77_G	147_G	0.558	0.28
22_G	179_K	0.558	0.28
140_I	144_L	0.557	0.28
168_S	174_R	0.555	0.28
4_R	116_G	0.552	0.28
73_L	171_K	0.552	0.28
148_N	159_V	0.551	0.28
149_K	188_F	0.550	0.27
55_I	102_A	0.548	0.27
40_E	135_E	0.547	0.27
95_T	110_A	0.547	0.27
39_A	43_K	0.547	0.27
47_F	156_L	0.547	0.27
143_A	157_R	0.545	0.27
166_D	169_V	0.544	0.27
1_Q	158_E	0.543	0.27
1_Q	151_D	0.542	0.27
19_Y	179_K	0.541	0.27
46_S	57_Y	0.537	0.27
149_K	153_E	0.537	0.27
22_G	25_G	0.531	0.26
89_V	158_E	0.531	0.26
12_L	16_L	0.529	0.26
39_A	177_R	0.527	0.26
131_E	134_E	0.527	0.26
169_V	181_L	0.526	0.26
8_L	46_S	0.526	0.26
96_A	105_T	0.525	0.26
15_R	35_A	0.524	0.26
76_G	81_R	0.523	0.26
63_A	89_V	0.523	0.26
103_Q	147_G	0.523	0.26
57_Y	69_S	0.522	0.26
105_T	112_A	0.521	0.26
86_G	141_L	0.520	0.25
81_R	86_G	0.520	0.25
93_V	97_S	0.516	0.25
32_R	183_I	0.515	0.25
13_K	166_D	0.514	0.25
114_E	141_L	0.512	0.25
60_V	185_G	0.511	0.25
98_S	142_E	0.510	0.25
69_S	78_F	0.510	0.25
21_E	30_A	0.509	0.25
90_K	162_K	0.509	0.25
103_Q	106_M	0.505	0.25
162_K	166_D	0.503	0.24
50_E	132_L	0.503	0.24
54_T	160_C	0.503	0.24
75_V	116_G	0.502	0.24
18_P	30_A	0.500	0.24

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3k62A	1	0.25	10.7	0.949	Contact Map
3msvA	2	0.4712	5	0.956	Contact Map
2wscG	1	0.3029	5	0.956	Contact Map
1yviA	1	0.6635	3.4	0.96	Contact Map
4g78A	1	0.649	3.2	0.96	Contact Map
2rawB	1	0.2692	2.9	0.961	Contact Map
2qzgA	2	0.2981	2.7	0.962	Contact Map
3a8yC	1	0.1202	2.7	0.962	Contact Map
1nfnA	1	0.2885	2.5	0.962	Contact Map
2zg6A	2	0.3173	2.2	0.963	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0073 seconds.