O-ag_pol_Wzy - PFAM28P - GREMLIN Contacts

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O-ag_pol_Wzy - O-antigen polysaccharide polymerase Wzy

PFAM:	PF14296	Sequences: LLILLFLIGLFFNNLSFLLILLLLIFILLIIYSLKKLKIFSPYFLFLITFFLFLFGRPFLLYFFGYYDSIFGLDFFSEDIINKALLLSLLGLLSFLLGYLLFKKKKRKLNKKKILLSYNSKLIKNLRKVGLILFLISFLPFLLYLYGGLLYVLSGGYLALYTSFLSSLPGLLSLLSSFFLIALLLFLASKPSKKKLLLILLLFLLYLLLSLLTGSRGPFILLLLALLWYYFYRNRKKKKIKKKKLILLLLLAIVLLVLLSLIGYIRSGGSISSSSLLNSILDFFYEQGGSFRVLAYTIEYVDSLPNGEPYTYGKTYLYFLSGIIPNLFGLIPFPSGNSVELALEGNSLSDWLTYLLNPDAYLSGGGLGFSYIAEAYLNFGYLGVIIFMFLLGFLLRKLYKKFKRNPFLLALYLILLPNLLFLPRGSFLSFLRPLLWYLIILLIILIF	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	447 (429)
Sequences:	1343 (1297)
Seq/√Len:	62.6
META:	0.754

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
375_A	387_F	9.035	1.00
91_G	388_M	6.761	1.00
94_S	385_I	5.670	1.00
315_T	378_N	5.331	1.00
98_G	392_G	5.146	1.00
379_F	383_G	4.911	1.00
263_G	266_R	4.865	1.00
432_R	436_W	4.805	1.00
371_Y	388_M	3.701	1.00
374_E	378_N	3.484	1.00
87_L	384_V	3.297	1.00
297_T	373_A	3.251	1.00
351_W	369_F	3.210	1.00
98_G	389_F	3.181	1.00
156_G	159_A	3.137	1.00
368_G	424_R	3.012	1.00
313_G	379_F	2.887	1.00
313_G	378_N	2.663	1.00
46_F	50_F	2.634	1.00
348_L	351_W	2.605	1.00
325_P	328_F	2.603	1.00
91_G	98_G	2.594	1.00
369_F	378_N	2.544	1.00
421_F	425_G	2.347	1.00
369_F	375_A	2.317	1.00
91_G	384_V	2.299	1.00
214_G	368_G	2.276	1.00
91_G	95_F	2.258	1.00
241_K	244_K	2.246	1.00
325_P	329_G	2.246	1.00
130_G	182_A	2.187	1.00
311_T	315_T	2.151	1.00
220_I	259_L	2.145	1.00
316_Y	378_N	2.129	1.00
301_V	377_L	2.125	1.00
283_F	287_Q	2.123	1.00
102_F	393_F	2.050	1.00
130_G	137_S	2.045	1.00
370_S	424_R	2.044	1.00
433_P	436_W	2.041	1.00
329_G	332_P	2.018	1.00
371_Y	375_A	2.016	1.00
94_S	98_G	1.994	1.00
326_N	332_P	1.973	1.00
372_I	388_M	1.962	1.00
375_A	378_N	1.961	1.00
392_G	396_R	1.952	1.00
370_S	373_A	1.938	1.00
88_S	91_G	1.933	1.00
98_G	102_F	1.923	1.00
288_G	293_V	1.923	1.00
217_G	421_F	1.898	1.00
313_G	316_Y	1.864	1.00
328_F	332_P	1.835	1.00
366_G	369_F	1.833	1.00
231_F	234_N	1.829	1.00
338_S	342_A	1.827	1.00
43_Y	96_L	1.788	1.00
217_G	221_L	1.757	0.99
228_W	232_Y	1.752	0.99
326_N	329_G	1.706	0.99
157_Y	368_G	1.703	0.99
348_L	353_T	1.700	0.99
339_V	342_A	1.700	0.99
312_Y	315_T	1.661	0.99
295_A	298_I	1.659	0.99
345_G	348_L	1.621	0.99
433_P	437_Y	1.600	0.99
129_V	394_L	1.592	0.99
328_F	331_I	1.586	0.99
50_F	53_F	1.552	0.99
42_P	47_L	1.541	0.99
423_P	426_S	1.539	0.99
286_E	290_S	1.523	0.99
369_F	426_S	1.516	0.98
221_L	421_F	1.507	0.98
49_T	423_P	1.489	0.98
315_T	318_Y	1.488	0.98
138_F	142_L	1.482	0.98
337_N	341_L	1.465	0.98
133_L	246_I	1.460	0.98
39_I	42_P	1.453	0.98
376_Y	380_G	1.445	0.98
102_F	396_R	1.431	0.98
302_D	305_P	1.430	0.98
52_L	425_G	1.429	0.98
323_I	332_P	1.425	0.98
369_F	374_E	1.423	0.98
372_I	384_V	1.410	0.98
305_P	308_E	1.390	0.97
391_L	422_L	1.388	0.97
293_V	298_I	1.384	0.97
41_S	399_Y	1.380	0.97
376_Y	381_Y	1.379	0.97
56_G	288_G	1.375	0.97
324_I	328_F	1.373	0.97
292_R	295_A	1.371	0.97
87_L	372_I	1.369	0.97
397_K	401_K	1.369	0.97
53_F	369_F	1.367	0.97
370_S	374_E	1.366	0.97
316_Y	374_E	1.363	0.97
54_L	57_R	1.358	0.97
22_L	26_F	1.356	0.97
426_S	429_S	1.354	0.97
229_Y	233_R	1.325	0.96
152_V	156_G	1.321	0.96
40_F	44_F	1.317	0.96
364_G	370_S	1.310	0.96
260_S	263_G	1.309	0.96
95_F	412_Y	1.305	0.96
358_P	367_L	1.295	0.96
295_A	372_I	1.293	0.96
87_L	91_G	1.287	0.96
369_F	377_L	1.282	0.96
313_G	317_L	1.277	0.96
243_K	254_V	1.273	0.95
301_V	305_P	1.263	0.95
178_F	319_F	1.261	0.95
15_L	18_L	1.258	0.95
208_L	212_L	1.254	0.95
217_G	291_F	1.242	0.95
222_L	394_L	1.235	0.95
320_L	325_P	1.230	0.95
371_Y	374_E	1.226	0.94
284_F	287_Q	1.222	0.94
325_P	332_P	1.221	0.94
283_F	286_E	1.218	0.94
133_L	137_S	1.215	0.94
388_M	392_G	1.214	0.94
335_S	338_S	1.213	0.94
98_G	132_I	1.202	0.94
41_S	54_L	1.202	0.94
369_F	373_A	1.201	0.94
42_P	399_Y	1.194	0.94
239_K	253_I	1.190	0.93
297_T	301_V	1.190	0.93
352_L	367_L	1.183	0.93
53_F	370_S	1.175	0.93
349_S	352_L	1.163	0.93
263_G	286_E	1.158	0.93
353_T	365_G	1.158	0.93
378_N	426_S	1.156	0.92
216_R	424_R	1.153	0.92
210_S	213_T	1.150	0.92
436_W	439_I	1.149	0.92
348_L	369_F	1.142	0.92
53_F	56_G	1.140	0.92
99_Y	387_F	1.140	0.92
338_S	341_L	1.134	0.92
95_F	392_G	1.131	0.92
64_F	129_V	1.125	0.91
161_Y	361_Y	1.114	0.91
99_Y	392_G	1.097	0.90
225_A	390_L	1.097	0.90
99_Y	396_R	1.094	0.90
118_Y	390_L	1.093	0.90
284_F	387_F	1.089	0.90
291_F	295_A	1.089	0.90
338_S	374_E	1.088	0.90
426_S	432_R	1.085	0.90
87_L	381_Y	1.084	0.90
101_L	105_K	1.083	0.90
126_L	130_G	1.078	0.90
290_S	293_V	1.067	0.89
290_S	352_L	1.065	0.89
146_Y	419_L	1.065	0.89
305_P	313_G	1.065	0.89
395_L	419_L	1.064	0.89
205_L	208_L	1.064	0.89
320_L	332_P	1.062	0.89
38_K	41_S	1.044	0.88
311_T	378_N	1.044	0.88
429_S	433_P	1.040	0.88
229_Y	413_L	1.039	0.88
349_S	366_G	1.039	0.88
211_L	219_F	1.038	0.88
77_S	80_I	1.038	0.88
202_L	404_R	1.037	0.88
168_L	220_I	1.031	0.87
348_L	374_E	1.029	0.87
368_G	374_E	1.027	0.87
122_L	126_L	1.025	0.87
373_A	377_L	1.024	0.87
117_S	254_V	1.023	0.87
39_I	44_F	1.019	0.87
438_L	442_L	1.017	0.87
238_K	242_K	1.015	0.87
375_A	422_L	1.008	0.86
375_A	388_M	1.007	0.86
84_A	88_S	1.007	0.86
54_L	369_F	1.001	0.86
327_L	401_K	0.996	0.86
378_N	423_P	0.995	0.85
97_L	385_I	0.994	0.85
256_L	268_G	0.991	0.85
396_R	399_Y	0.987	0.85
257_V	266_R	0.986	0.85
127_R	130_G	0.985	0.85
219_F	432_R	0.985	0.85
174_L	177_S	0.984	0.85
369_F	423_P	0.975	0.84
323_I	328_F	0.974	0.84
288_G	291_F	0.973	0.84
262_I	265_I	0.969	0.84
48_I	56_G	0.966	0.84
24_L	32_Y	0.964	0.84
54_L	423_P	0.964	0.84
288_G	368_G	0.956	0.83
146_Y	150_L	0.956	0.83
289_G	293_V	0.954	0.83
85_L	89_L	0.952	0.83
382_L	390_L	0.950	0.83
247_L	250_L	0.950	0.83
135_L	324_I	0.949	0.83
95_F	395_L	0.946	0.82
91_G	392_G	0.946	0.82
356_L	367_L	0.944	0.82
95_F	348_L	0.944	0.82
422_L	425_G	0.938	0.82
213_T	365_G	0.937	0.82
420_L	431_L	0.936	0.82
84_A	296_Y	0.930	0.81
84_A	295_A	0.928	0.81
175_L	178_F	0.928	0.81
348_L	357_N	0.923	0.81
53_F	217_G	0.922	0.81
235_R	239_K	0.915	0.80
168_L	400_K	0.914	0.80
168_L	306_N	0.914	0.80
230_Y	235_R	0.914	0.80
316_Y	375_A	0.911	0.80
369_F	425_G	0.910	0.80
143_L	258_L	0.909	0.80
129_V	144_Y	0.908	0.80
14_N	17_F	0.907	0.80
286_E	295_A	0.899	0.79
185_L	249_L	0.897	0.79
288_G	370_S	0.896	0.79
378_N	428_L	0.894	0.79
313_G	321_S	0.893	0.79
227_L	231_F	0.893	0.79
121_K	194_K	0.892	0.79
432_R	435_L	0.889	0.78
219_F	222_L	0.889	0.78
128_K	205_L	0.887	0.78
335_S	341_L	0.887	0.78
217_G	429_S	0.886	0.78
368_G	375_A	0.877	0.77
94_S	389_F	0.877	0.77
197_L	202_L	0.876	0.77
221_L	377_L	0.871	0.77
176_S	370_S	0.868	0.77
399_Y	412_Y	0.868	0.77
50_F	54_L	0.866	0.76
324_I	332_P	0.865	0.76
325_P	331_I	0.865	0.76
300_Y	369_F	0.862	0.76
43_Y	53_F	0.862	0.76
322_G	329_G	0.861	0.76
178_F	187_L	0.859	0.76
360_A	365_G	0.859	0.76
376_Y	379_F	0.858	0.76
378_N	427_F	0.858	0.76
72_G	75_F	0.856	0.76
38_K	42_P	0.854	0.75
422_L	430_F	0.849	0.75
235_R	238_K	0.848	0.75
94_S	382_L	0.846	0.75
230_Y	238_K	0.845	0.75
112_K	136_I	0.843	0.75
116_L	134_F	0.843	0.75
169_P	329_G	0.841	0.74
255_L	349_S	0.841	0.74
311_T	314_K	0.840	0.74
53_F	290_S	0.839	0.74
294_L	297_T	0.838	0.74
178_F	182_A	0.837	0.74
367_L	423_P	0.837	0.74
419_L	444_I	0.835	0.74
417_P	425_G	0.829	0.73
436_W	440_I	0.829	0.73
269_G	373_A	0.822	0.73
286_E	368_G	0.820	0.72
369_F	424_R	0.820	0.72
30_I	205_L	0.817	0.72
337_N	340_E	0.817	0.72
366_G	373_A	0.814	0.72
197_L	240_I	0.814	0.72
46_F	54_L	0.811	0.72
434_L	439_I	0.810	0.72
90_L	117_S	0.809	0.71
62_Y	65_G	0.809	0.71
43_Y	50_F	0.809	0.71
271_I	384_V	0.806	0.71
53_F	57_R	0.805	0.71
52_L	228_W	0.803	0.71
374_E	379_F	0.801	0.71
214_G	290_S	0.800	0.71
249_L	254_V	0.799	0.70
427_F	430_F	0.798	0.70
336_G	350_D	0.797	0.70
29_L	49_T	0.794	0.70
29_L	33_S	0.793	0.70
198_L	376_Y	0.792	0.70
230_Y	234_N	0.790	0.70
101_L	224_L	0.787	0.69
260_S	266_R	0.787	0.69
194_K	197_L	0.786	0.69
321_S	325_P	0.784	0.69
205_L	310_Y	0.784	0.69
287_Q	369_F	0.784	0.69
35_K	38_K	0.782	0.69
123_I	127_R	0.780	0.69
389_F	393_F	0.779	0.69
40_F	43_Y	0.774	0.68
317_L	320_L	0.773	0.68
97_L	101_L	0.772	0.68
433_P	438_L	0.767	0.67
157_Y	288_G	0.767	0.67
158_L	161_Y	0.766	0.67
288_G	294_L	0.766	0.67
248_L	327_L	0.764	0.67
384_V	392_G	0.762	0.67
290_S	368_G	0.760	0.67
101_L	104_K	0.760	0.67
415_L	425_G	0.758	0.66
396_R	400_K	0.758	0.66
254_V	291_F	0.757	0.66
136_I	202_L	0.756	0.66
316_Y	319_F	0.755	0.66
15_L	19_L	0.754	0.66
29_L	204_L	0.753	0.66
98_G	388_M	0.753	0.66
284_F	310_Y	0.753	0.66
357_N	367_L	0.752	0.66
262_I	281_L	0.750	0.66
78_E	382_L	0.749	0.65
252_A	257_V	0.749	0.65
224_L	283_F	0.746	0.65
376_Y	384_V	0.746	0.65
351_W	355_L	0.745	0.65
45_L	306_N	0.740	0.65
91_G	139_L	0.740	0.65
373_A	399_Y	0.737	0.64
45_L	49_T	0.735	0.64
247_L	251_L	0.735	0.64
14_N	19_L	0.735	0.64
216_R	366_G	0.731	0.64
84_A	314_K	0.729	0.63
87_L	98_G	0.727	0.63
28_L	32_Y	0.727	0.63
132_I	404_R	0.726	0.63
153_L	156_G	0.725	0.63
295_A	374_E	0.722	0.63
419_L	425_G	0.721	0.63
47_L	92_L	0.720	0.62
98_G	232_Y	0.720	0.62
374_E	426_S	0.719	0.62
52_L	56_G	0.718	0.62
91_G	94_S	0.717	0.62
293_V	383_G	0.717	0.62
84_A	376_Y	0.716	0.62
40_F	208_L	0.713	0.62
53_F	58_P	0.713	0.62
27_I	45_L	0.712	0.62
210_S	216_R	0.712	0.62
189_S	349_S	0.711	0.61
51_F	54_L	0.710	0.61
297_T	348_L	0.709	0.61
12_F	16_S	0.709	0.61
351_W	357_N	0.709	0.61
153_L	157_Y	0.707	0.61
55_F	89_L	0.707	0.61
53_F	225_A	0.704	0.61
27_I	385_I	0.704	0.61
397_K	400_K	0.703	0.61
48_I	392_G	0.702	0.60
353_T	392_G	0.701	0.60
297_T	369_F	0.700	0.60
12_F	15_L	0.699	0.60
201_L	328_F	0.698	0.60
124_K	155_G	0.696	0.60
201_L	205_L	0.695	0.60
30_I	209_L	0.694	0.60
173_S	240_I	0.691	0.59
54_L	370_S	0.691	0.59
224_L	257_V	0.689	0.59
286_E	289_G	0.686	0.59
96_L	290_S	0.685	0.59
251_L	255_L	0.685	0.59
203_F	219_F	0.685	0.59
369_F	421_F	0.685	0.59
118_Y	240_I	0.684	0.58
384_V	388_M	0.682	0.58
134_F	182_A	0.679	0.58
26_F	205_L	0.679	0.58
421_F	428_L	0.678	0.58
60_L	65_G	0.677	0.58
273_S	385_I	0.677	0.58
136_I	197_L	0.676	0.58
135_L	150_L	0.676	0.58
243_K	339_V	0.674	0.57
398_L	430_F	0.674	0.57
31_I	144_Y	0.672	0.57
382_L	435_L	0.671	0.57
319_F	326_N	0.670	0.57
185_L	407_F	0.670	0.57
99_Y	102_F	0.669	0.57
434_L	437_Y	0.669	0.57
92_L	428_L	0.668	0.57
203_F	372_I	0.667	0.57
143_L	254_V	0.667	0.57
30_I	33_S	0.667	0.57
305_P	310_Y	0.664	0.56
246_I	251_L	0.663	0.56
46_F	51_F	0.662	0.56
373_A	425_G	0.662	0.56
378_N	422_L	0.660	0.56
243_K	246_I	0.657	0.55
214_G	424_R	0.657	0.55
13_N	17_F	0.657	0.55
293_V	422_L	0.655	0.55
250_L	264_Y	0.655	0.55
419_L	426_S	0.655	0.55
340_E	344_E	0.655	0.55
352_L	356_L	0.653	0.55
142_L	151_Y	0.653	0.55
22_L	29_L	0.653	0.55
232_Y	379_F	0.651	0.55
327_L	348_L	0.651	0.55
170_G	181_I	0.650	0.55
255_L	407_F	0.648	0.54
88_S	294_L	0.647	0.54
84_A	291_F	0.647	0.54
36_K	41_S	0.646	0.54
301_V	304_L	0.646	0.54
216_R	352_L	0.645	0.54
261_L	297_T	0.644	0.54
85_L	300_Y	0.643	0.54
63_F	66_Y	0.643	0.54
310_Y	314_K	0.643	0.54
217_G	420_L	0.641	0.54
41_S	376_Y	0.641	0.54
91_G	383_G	0.641	0.54
44_F	48_I	0.639	0.53
207_L	392_G	0.636	0.53
378_N	388_M	0.636	0.53
91_G	372_I	0.635	0.53
378_N	383_G	0.635	0.53
338_S	348_L	0.635	0.53
319_F	325_P	0.635	0.53
275_S	282_D	0.633	0.53
180_L	386_I	0.633	0.53
219_F	372_I	0.633	0.53
162_T	211_L	0.632	0.53
94_S	101_L	0.631	0.52
74_D	136_I	0.631	0.52
130_G	140_P	0.629	0.52
137_S	140_P	0.629	0.52
304_L	430_F	0.629	0.52
217_G	329_G	0.628	0.52
14_N	23_L	0.628	0.52
91_G	371_Y	0.628	0.52
216_R	260_S	0.627	0.52
109_L	247_L	0.626	0.52
287_Q	293_V	0.626	0.52
90_L	381_Y	0.623	0.52
251_L	324_I	0.622	0.51
127_R	137_S	0.622	0.51
130_G	187_L	0.621	0.51
217_G	369_F	0.619	0.51
289_G	365_G	0.619	0.51
194_K	405_N	0.618	0.51
225_A	416_L	0.618	0.51
432_R	437_Y	0.618	0.51
375_A	427_F	0.617	0.51
127_R	152_V	0.617	0.51
317_L	378_N	0.617	0.51
310_Y	444_I	0.616	0.51
325_P	377_L	0.612	0.50
287_Q	301_V	0.611	0.50
19_L	139_L	0.611	0.50
131_L	394_L	0.611	0.50
222_L	365_G	0.610	0.50
233_R	288_G	0.610	0.50
191_P	195_K	0.608	0.50
126_L	403_K	0.608	0.50
313_G	320_L	0.606	0.50
159_A	190_K	0.606	0.50
96_L	102_F	0.605	0.49
123_I	324_I	0.605	0.49
186_F	189_S	0.605	0.49
12_F	19_L	0.604	0.49
137_S	371_Y	0.602	0.49
252_A	256_L	0.600	0.49
358_P	364_G	0.599	0.49
171_L	174_L	0.598	0.49
391_L	419_L	0.596	0.48
101_L	110_N	0.596	0.48
141_F	145_L	0.596	0.48
358_P	362_L	0.594	0.48
81_I	248_L	0.594	0.48
220_I	258_L	0.593	0.48
38_K	399_Y	0.592	0.48
337_N	342_A	0.592	0.48
50_F	220_I	0.592	0.48
157_Y	266_R	0.590	0.48
240_I	262_I	0.588	0.48
315_T	332_P	0.588	0.48
157_Y	186_F	0.587	0.47
321_S	324_I	0.585	0.47
202_L	244_K	0.585	0.47
423_P	428_L	0.584	0.47
192_S	240_I	0.584	0.47
25_I	305_P	0.583	0.47
21_L	152_V	0.582	0.47
34_L	241_K	0.582	0.47
157_Y	364_G	0.581	0.47
49_T	53_F	0.581	0.47
25_I	202_L	0.579	0.47
309_P	313_G	0.579	0.47
148_G	310_Y	0.578	0.46
58_P	62_Y	0.577	0.46
152_V	346_N	0.577	0.46
176_S	181_I	0.577	0.46
95_F	248_L	0.576	0.46
336_G	342_A	0.576	0.46
346_N	349_S	0.575	0.46
228_W	332_P	0.574	0.46
240_I	421_F	0.574	0.46
225_A	229_Y	0.573	0.46
189_S	250_L	0.573	0.46
48_I	101_L	0.570	0.45
41_S	129_V	0.570	0.45
23_L	281_L	0.569	0.45
217_G	366_G	0.568	0.45
74_D	254_V	0.568	0.45
213_T	377_L	0.568	0.45
168_L	176_S	0.567	0.45
366_G	425_G	0.567	0.45
161_Y	347_S	0.567	0.45
76_F	81_I	0.567	0.45
410_A	420_L	0.567	0.45
157_Y	173_S	0.566	0.45
31_I	139_L	0.566	0.45
215_S	367_L	0.566	0.45
353_T	369_F	0.566	0.45
228_W	357_N	0.564	0.45
371_Y	423_P	0.564	0.45
262_I	266_R	0.564	0.45
101_L	249_L	0.563	0.45
99_Y	425_G	0.560	0.44
127_R	131_L	0.560	0.44
59_F	323_I	0.559	0.44
301_V	372_I	0.559	0.44
309_P	376_Y	0.558	0.44
215_S	373_A	0.557	0.44
65_G	407_F	0.557	0.44
131_L	135_L	0.555	0.44
291_F	369_F	0.554	0.44
317_L	325_P	0.554	0.44
62_Y	66_Y	0.553	0.44
118_Y	223_L	0.553	0.44
75_F	89_L	0.553	0.44
352_L	357_N	0.552	0.43
411_L	437_Y	0.552	0.43
206_Y	374_E	0.551	0.43
417_P	439_I	0.551	0.43
82_N	372_I	0.550	0.43
266_R	288_G	0.550	0.43
176_S	183_L	0.549	0.43
48_I	193_K	0.547	0.43
148_G	164_F	0.547	0.43
99_Y	326_N	0.547	0.43
22_L	30_I	0.546	0.43
351_W	366_G	0.545	0.43
162_T	220_I	0.545	0.43
21_L	224_L	0.544	0.43
323_I	391_L	0.543	0.42
29_L	32_Y	0.541	0.42
229_Y	283_F	0.541	0.42
401_K	404_R	0.541	0.42
23_L	386_I	0.541	0.42
360_A	363_S	0.541	0.42
353_T	357_N	0.540	0.42
308_E	393_F	0.540	0.42
128_K	199_I	0.540	0.42
254_V	441_L	0.538	0.42
230_Y	395_L	0.538	0.42
259_L	404_R	0.537	0.42
381_Y	410_A	0.536	0.42
300_Y	304_L	0.536	0.42
180_L	390_L	0.535	0.42
80_I	83_K	0.534	0.41
194_K	254_V	0.534	0.41
149_L	153_L	0.534	0.41
187_L	253_I	0.533	0.41
23_L	27_I	0.532	0.41
316_Y	321_S	0.531	0.41
80_I	227_L	0.528	0.41
58_P	64_F	0.527	0.41
194_K	397_K	0.527	0.41
393_F	401_K	0.527	0.41
25_I	197_L	0.526	0.41
70_I	73_L	0.526	0.41
433_P	439_I	0.526	0.41
217_G	365_G	0.525	0.40
389_F	437_Y	0.522	0.40
29_L	393_F	0.522	0.40
249_L	263_G	0.522	0.40
284_F	288_G	0.522	0.40
58_P	256_L	0.521	0.40
113_K	133_L	0.521	0.40
196_L	252_A	0.520	0.40
305_P	351_W	0.520	0.40
115_L	398_L	0.518	0.40
200_L	207_L	0.517	0.40
252_A	274_S	0.516	0.39
339_V	343_L	0.513	0.39
60_L	67_Y	0.512	0.39
225_A	373_A	0.512	0.39
66_Y	278_N	0.512	0.39
83_K	282_D	0.512	0.39
215_S	421_F	0.511	0.39
350_D	361_Y	0.511	0.39
219_F	373_A	0.511	0.39
182_A	291_F	0.510	0.39
262_I	420_L	0.509	0.39
129_V	137_S	0.509	0.39
375_A	383_G	0.507	0.38
185_L	291_F	0.507	0.38
125_N	128_K	0.507	0.38
201_L	409_L	0.507	0.38
105_K	108_K	0.506	0.38
206_Y	411_L	0.505	0.38
241_K	251_L	0.504	0.38
46_F	221_L	0.502	0.38
178_F	185_L	0.502	0.38
145_L	152_V	0.501	0.38
345_G	351_W	0.501	0.38
261_L	265_I	0.501	0.38
218_P	358_P	0.500	0.38
29_L	47_L	0.500	0.38

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2jwaA	2	0.0984	1.8	0.969	Contact Map
3giaA	1	0.226	1.4	0.971	Contact Map
2l2tA	2	0.0984	1.2	0.972	Contact Map
1iijA	1	0.0783	1.2	0.972	Contact Map
2ks1B	1	0.0984	1.1	0.973	Contact Map
2ksfA	1	0.2304	1.1	0.973	Contact Map
2l9uA	2	0.0872	0.9	0.974	Contact Map
1v54B	1	0.1611	0.7	0.976	Contact Map
2gsmB	1	0.1834	0.7	0.976	Contact Map
4b19A	1	0.0671	0.7	0.976	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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