GREMLIN Database
YWFCY - YWFCY protein
PFAM: PF14293 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 60 (59)
Sequences: 1503 (868)
Seq/√Len: 113.0
META: 0.881

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
15_F19_I3.7851.00
35_A39_W3.6051.00
43_S46_T2.9581.00
34_G37_K2.8101.00
33_Y47_D2.5951.00
3_G10_R2.4341.00
21_I25_L2.3051.00
36_F42_T2.0101.00
15_F18_L1.9491.00
1_Q6_E1.5961.00
13_L16_T1.5481.00
44_G48_R1.4951.00
10_R14_D1.4891.00
8_G45_I1.4341.00
46_T50_L1.3221.00
36_F46_T1.2150.99
56_T59_L1.1990.99
1_Q10_R1.1820.99
1_Q8_G1.1810.99
3_G6_E1.1340.99
48_R51_L1.0950.98
53_I56_T1.0650.98
14_D24_L1.0590.98
6_E10_R1.0570.98
42_T46_T1.0520.98
33_Y50_L1.0510.98
37_K42_T1.0440.98
35_A38_E1.0240.97
39_W43_S0.9710.96
8_G12_I0.9640.96
37_K47_D0.9220.95
12_I23_I0.9220.95
7_Q10_R0.9160.95
26_L30_Y0.8940.94
19_I22_L0.8840.94
8_G16_T0.8830.94
13_L17_R0.8820.94
30_Y54_Q0.8540.93
32_C35_A0.8390.92
51_L55_R0.8360.92
11_K17_R0.8180.91
7_Q19_I0.7990.90
35_A41_L0.7930.89
24_L36_F0.7910.89
25_L34_G0.7900.89
1_Q34_G0.7820.89
30_Y50_L0.7390.86
3_G7_Q0.7380.86
2_T6_E0.7290.85
13_L28_F0.7180.84
23_I51_L0.6980.83
48_R52_N0.6910.82
17_R20_S0.6610.79
15_F25_L0.6500.78
33_Y42_T0.6490.78
24_L35_A0.6390.77
44_G51_L0.6330.76
34_G51_L0.6300.76
29_Y36_F0.6240.75
45_I48_R0.6240.75
2_T10_R0.6160.74
20_S60_F0.6150.74
6_E30_Y0.6050.73
38_E44_G0.6030.73
18_L22_L0.5950.72
38_E55_R0.5920.71
18_L47_D0.5760.69
16_T23_I0.5680.68
2_T27_H0.5570.67
52_N56_T0.5550.66
4_E10_R0.5500.66
24_L27_H0.5470.65
29_Y55_R0.5460.65
52_N58_G0.5390.64
14_D17_R0.5370.64
37_K51_L0.5340.63
2_T14_D0.5340.63
37_K40_G0.5320.63
13_L25_L0.5320.63
26_L60_F0.5230.62
51_L54_Q0.5190.61
24_L40_G0.5190.61
46_T49_I0.5190.61
6_E31_Y0.5150.61
24_L44_G0.5110.60
28_F35_A0.5010.58
36_F39_W0.5010.58
33_Y36_F0.5000.58
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
4n7bA 1 0 7.7 0.894 Contact Map
3dkxA 3 0.9333 6.1 0.899 Contact Map
4f8xA 1 0.9667 6 0.899 Contact Map
4ha4A 4 0.95 5.9 0.9 Contact Map
2bs2C 2 1 5.3 0.902 Contact Map
1xyzA 1 0.9667 4.5 0.905 Contact Map
2xfrA 1 0.9833 4.2 0.906 Contact Map
4j7cI 2 1 4 0.907 Contact Map
3vx8D 1 1 3.9 0.907 Contact Map
4f9dA 1 0.95 3.9 0.908 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0045 seconds.