DUF4331 - PFAM28P - GREMLIN Contacts

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DUF4331 - Domain of unknown function (DUF4331)

PFAM:	PF14224	Sequences: SSHREAPLISKDPKADNTDVYAFVSPDRPDTVTLIANYIPLEEPAGGPNFYEFDDDVLYEIHIDNNGDGKEDITYQFRFKTTLRNPNTFLYNTGTSLDDPNLNVRQTYTVTRVRGGGRTGTRTVLGTNLPVPPSNIGPRSTPNYAALAAQAIYTLPGSTGGRVFAGQRDDPFFVDLGAIFDLLNGAPLGPNAAGPGVDTLAGFNVHSIALEVPISCLTRDGASATNPVIGVWATASRRQVRVLGGDGTEVSGPWVQVSRLGNPLVNEVVIPLGDKDRFNASEPKDDAQFAKYVTNPELAALLNALYGLPAPTTPRTDLVAIFLTGIPGLNQPTGVTPADMLRLNTAIPPTPAPNQSRLGVLGGDLAGFPNGRRLGDDVVDIELRAVAGALLPDPAPALPLGDGVDANDAVPFLSTFPYLATP	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	422 (420)
Sequences:	4672 (3126)
Seq/√Len:	152.5
META:	0.919

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
60_E	76_Q	4.121	1.00
126_G	129_L	3.696	1.00
274_D	292_Y	3.336	1.00
382_E	386_V	3.155	1.00
368_F	382_E	2.998	1.00
169_D	198_D	2.792	1.00
360_V	365_L	2.746	1.00
238_R	254_W	2.689	1.00
43_E	203_F	2.668	1.00
265_V	270_I	2.650	1.00
130_P	153_Y	2.630	1.00
24_V	214_I	2.587	1.00
58_L	254_W	2.572	1.00
170_D	200_L	2.552	1.00
224_A	227_P	2.492	1.00
294_T	319_V	2.478	1.00
84_R	105_R	2.465	1.00
20_V	231_V	2.453	1.00
66_N	72_D	2.450	1.00
17_N	233_A	2.422	1.00
274_D	277_R	2.380	1.00
58_L	76_Q	2.367	1.00
73_I	112_R	2.346	1.00
356_S	362_G	2.320	1.00
92_N	140_S	2.294	1.00
222_A	227_P	2.226	1.00
62_H	234_T	2.226	1.00
35_I	207_S	2.225	1.00
145_A	421_T	2.224	1.00
60_E	236_S	2.222	1.00
28_R	31_T	2.204	1.00
298_L	386_V	2.195	1.00
42_E	206_H	2.139	1.00
38_Y	233_A	2.123	1.00
171_P	412_F	2.099	1.00
35_I	209_A	2.071	1.00
76_Q	113_V	2.040	1.00
295_N	300_A	2.023	1.00
38_Y	235_A	2.007	1.00
239_Q	253_P	1.976	1.00
110_V	208_I	1.975	1.00
332_P	335_V	1.965	1.00
183_L	302_L	1.963	1.00
22_A	231_V	1.950	1.00
290_A	294_T	1.921	1.00
143_N	146_A	1.920	1.00
37_N	207_S	1.899	1.00
64_D	68_D	1.871	1.00
55_D	81_T	1.861	1.00
15_A	57_V	1.850	1.00
62_H	74_T	1.843	1.00
265_V	293_V	1.837	1.00
277_R	288_Q	1.823	1.00
161_G	216_C	1.810	1.00
227_P	346_A	1.787	1.00
129_L	153_Y	1.782	1.00
145_A	149_A	1.778	1.00
329_L	333_T	1.742	1.00
179_I	268_V	1.711	1.00
232_W	340_M	1.710	1.00
62_H	71_E	1.703	1.00
214_I	345_T	1.703	1.00
154_T	162_R	1.671	1.00
82_T	105_R	1.669	1.00
18_T	37_N	1.666	1.00
330_N	333_T	1.663	1.00
27_D	33_T	1.655	1.00
285_D	288_Q	1.647	1.00
299_A	386_V	1.646	1.00
327_P	331_Q	1.640	1.00
17_N	38_Y	1.632	1.00
162_R	211_E	1.623	1.00
20_V	233_A	1.614	1.00
169_D	407_N	1.610	1.00
132_P	151_A	1.603	1.00
329_L	332_P	1.582	1.00
83_L	272_L	1.578	1.00
25_S	33_T	1.572	1.00
320_A	327_P	1.562	1.00
95_T	101_N	1.553	1.00
68_D	72_D	1.549	1.00
112_R	216_C	1.544	1.00
31_T	211_E	1.541	1.00
277_R	281_S	1.538	1.00
76_Q	111_T	1.497	1.00
74_T	113_V	1.475	1.00
9_I	15_A	1.468	1.00
261_G	341_L	1.462	1.00
32_V	343_L	1.462	1.00
82_T	107_T	1.454	1.00
270_I	292_Y	1.451	1.00
32_V	214_I	1.437	1.00
281_S	288_Q	1.429	1.00
52_E	104_V	1.425	1.00
237_R	243_L	1.423	1.00
393_D	396_P	1.422	1.00
148_A	168_R	1.418	1.00
281_S	289_F	1.412	1.00
349_P	366_A	1.407	1.00
80_K	107_T	1.404	1.00
164_F	168_R	1.402	1.00
95_T	99_D	1.401	1.00
351_P	354_N	1.383	1.00
171_P	419_L	1.382	1.00
53_F	165_A	1.379	1.00
75_Y	112_R	1.378	1.00
413_L	420_A	1.377	1.00
298_L	382_E	1.371	1.00
270_I	293_V	1.366	1.00
128_N	132_P	1.363	1.00
207_S	419_L	1.355	1.00
58_L	113_V	1.354	1.00
271_P	274_D	1.354	1.00
185_G	189_G	1.337	1.00
39_I	206_H	1.336	1.00
410_V	420_A	1.326	1.00
187_P	190_P	1.321	1.00
281_S	285_D	1.318	1.00
28_R	162_R	1.318	1.00
265_V	269_V	1.317	1.00
36_A	233_A	1.315	1.00
83_L	104_V	1.311	1.00
331_Q	335_V	1.301	1.00
33_T	211_E	1.298	1.00
20_V	34_L	1.295	1.00
190_P	193_A	1.290	1.00
14_K	54_D	1.283	1.00
334_G	337_P	1.283	1.00
395_A	398_L	1.277	1.00
60_E	74_T	1.276	1.00
88_T	297_E	1.275	1.00
34_L	231_V	1.260	1.00
327_P	332_P	1.256	1.00
141_T	147_L	1.255	1.00
81_T	104_V	1.255	1.00
300_A	304_A	1.254	1.00
139_R	184_N	1.254	1.00
401_G	405_D	1.250	1.00
58_L	78_R	1.248	1.00
75_Y	216_C	1.246	1.00
58_L	236_S	1.246	1.00
71_E	234_T	1.244	1.00
63_I	217_L	1.238	1.00
155_L	160_G	1.236	1.00
24_V	349_P	1.236	1.00
114_R	117_G	1.233	1.00
77_F	110_V	1.229	1.00
350_T	353_P	1.223	1.00
78_R	111_T	1.222	1.00
322_F	339_D	1.210	1.00
241_R	251_S	1.207	1.00
34_L	212_V	1.206	1.00
232_W	282_E	1.205	1.00
154_T	158_S	1.203	1.00
77_F	163_V	1.201	1.00
311_P	391_L	1.201	1.00
168_R	413_L	1.200	1.00
294_T	316_T	1.198	1.00
62_H	236_S	1.195	1.00
149_A	152_I	1.193	1.00
39_I	53_F	1.188	1.00
277_R	289_F	1.179	1.00
146_A	150_Q	1.176	1.00
111_T	124_V	1.176	1.00
217_L	345_T	1.170	1.00
171_P	374_L	1.167	1.00
39_I	42_E	1.165	1.00
393_D	398_L	1.155	1.00
394_P	398_L	1.152	1.00
37_N	171_P	1.151	1.00
110_V	163_V	1.149	1.00
96_S	99_D	1.145	1.00
353_P	356_S	1.144	1.00
103_N	272_L	1.143	1.00
218_T	345_T	1.142	1.00
375_G	412_F	1.141	1.00
183_L	298_L	1.129	1.00
154_T	161_G	1.128	1.00
41_L	176_L	1.126	1.00
198_D	407_N	1.119	0.99
282_E	285_D	1.118	0.99
358_L	380_D	1.116	0.99
245_G	248_T	1.114	0.99
169_D	420_A	1.113	0.99
374_L	412_F	1.113	0.99
188_L	191_N	1.112	0.99
11_K	14_K	1.111	0.99
127_T	132_P	1.106	0.99
380_D	400_L	1.099	0.99
134_S	167_Q	1.094	0.99
223_S	227_P	1.093	0.99
70_K	284_K	1.092	0.99
34_L	63_I	1.089	0.99
186_A	189_G	1.088	0.99
96_S	101_N	1.087	0.99
86_P	273_G	1.084	0.99
321_I	385_A	1.083	0.99
185_G	188_L	1.082	0.99
129_L	132_P	1.082	0.99
186_A	190_P	1.080	0.99
411_P	420_A	1.078	0.99
212_V	217_L	1.077	0.99
170_D	198_D	1.073	0.99
328_G	333_T	1.059	0.99
222_A	226_N	1.058	0.99
394_P	397_A	1.055	0.99
361_L	389_A	1.054	0.99
307_G	311_P	1.053	0.99
136_I	141_T	1.046	0.99
401_G	404_V	1.044	0.99
34_L	217_L	1.039	0.99
36_A	61_I	1.035	0.99
97_L	150_Q	1.035	0.99
395_A	399_P	1.033	0.99
290_A	319_V	1.013	0.99
54_D	57_V	1.012	0.99
316_T	319_V	1.011	0.99
86_P	89_F	1.010	0.99
217_L	229_I	1.009	0.99
294_T	314_P	1.006	0.99
278_F	293_V	1.005	0.99
374_L	419_L	1.005	0.99
309_P	312_T	1.005	0.99
27_D	211_E	1.001	0.99
8_L	11_K	0.995	0.99
28_R	211_E	0.991	0.99
244_G	248_T	0.991	0.99
10_S	14_K	0.990	0.99
321_I	390_L	0.988	0.99
125_L	128_N	0.984	0.99
239_Q	255_V	0.984	0.99
290_A	337_P	0.982	0.99
109_T	124_V	0.982	0.99
97_L	151_A	0.978	0.99
1_S	260_L	0.970	0.99
104_V	272_L	0.970	0.99
15_A	235_A	0.969	0.99
75_Y	161_G	0.964	0.98
393_D	397_A	0.963	0.98
350_T	354_N	0.962	0.98
33_T	418_Y	0.961	0.98
131_V	134_S	0.960	0.98
93_T	103_N	0.956	0.98
325_G	329_L	0.955	0.98
380_D	402_D	0.954	0.98
37_N	168_R	0.953	0.98
300_A	303_N	0.949	0.98
78_R	254_W	0.949	0.98
391_L	397_A	0.939	0.98
41_L	46_G	0.937	0.98
290_A	323_L	0.933	0.98
326_I	329_L	0.933	0.98
360_V	363_G	0.932	0.98
303_N	309_P	0.932	0.98
113_V	118_R	0.930	0.98
357_R	405_D	0.928	0.98
347_I	366_A	0.922	0.98
327_P	330_N	0.919	0.98
303_N	310_A	0.917	0.98
325_G	328_G	0.915	0.98
291_K	295_N	0.914	0.98
246_D	249_E	0.913	0.98
63_I	75_Y	0.911	0.98
191_N	194_G	0.910	0.98
30_D	214_I	0.908	0.98
76_Q	118_R	0.908	0.98
396_P	399_P	0.905	0.98
27_D	31_T	0.905	0.98
24_V	30_D	0.904	0.98
17_N	20_V	0.904	0.98
262_N	382_E	0.904	0.98
407_N	412_F	0.904	0.98
307_G	310_A	0.904	0.98
25_S	28_R	0.901	0.98
79_F	208_I	0.901	0.98
407_N	410_V	0.899	0.98
20_V	260_L	0.898	0.98
11_K	54_D	0.898	0.98
107_T	130_P	0.898	0.98
84_R	98_D	0.896	0.98
395_A	400_L	0.895	0.98
176_L	179_I	0.887	0.97
387_A	398_L	0.887	0.97
12_D	237_R	0.881	0.97
355_Q	375_G	0.880	0.97
307_G	312_T	0.879	0.97
165_A	208_I	0.879	0.97
408_D	411_P	0.878	0.97
163_V	208_I	0.877	0.97
157_G	161_G	0.876	0.97
396_P	400_L	0.876	0.97
332_P	337_P	0.875	0.97
60_E	113_V	0.872	0.97
328_G	331_Q	0.871	0.97
174_V	379_V	0.870	0.97
295_N	313_T	0.870	0.97
392_P	397_A	0.868	0.97
179_I	183_L	0.866	0.97
93_T	101_N	0.864	0.97
360_V	390_L	0.864	0.97
161_G	212_V	0.862	0.97
212_V	216_C	0.855	0.97
156_P	159_T	0.853	0.97
80_K	128_N	0.853	0.97
12_D	15_A	0.852	0.97
308_L	312_T	0.850	0.97
269_V	386_V	0.847	0.97
135_N	138_P	0.845	0.97
131_V	167_Q	0.843	0.96
112_R	161_G	0.833	0.96
5_E	16_D	0.832	0.96
407_N	420_A	0.830	0.96
301_L	304_A	0.830	0.96
158_S	161_G	0.828	0.96
352_A	414_S	0.827	0.96
277_R	280_A	0.826	0.96
377_D	380_D	0.824	0.96
109_T	127_T	0.821	0.96
394_P	400_L	0.819	0.96
300_A	312_T	0.817	0.96
186_A	191_N	0.814	0.96
229_I	345_T	0.814	0.96
326_I	360_V	0.814	0.96
287_A	290_A	0.811	0.96
139_R	189_G	0.809	0.96
18_T	39_I	0.809	0.96
187_P	191_N	0.807	0.96
52_E	55_D	0.805	0.95
185_G	193_A	0.803	0.95
320_A	324_T	0.802	0.95
69_G	72_D	0.802	0.95
198_D	201_A	0.801	0.95
69_G	340_M	0.799	0.95
25_S	31_T	0.798	0.95
85_N	273_G	0.798	0.95
389_A	392_P	0.797	0.95
299_A	302_L	0.797	0.95
291_K	294_T	0.795	0.95
65_N	218_T	0.793	0.95
350_T	356_S	0.793	0.95
293_V	322_F	0.786	0.95
313_T	391_L	0.786	0.95
327_P	333_T	0.783	0.95
321_I	326_I	0.782	0.95
300_A	310_A	0.780	0.95
73_I	212_V	0.780	0.95
148_A	152_I	0.777	0.94
332_P	336_T	0.777	0.94
185_G	190_P	0.777	0.94
188_L	193_A	0.776	0.94
402_D	405_D	0.773	0.94
189_G	193_A	0.772	0.94
268_V	382_E	0.769	0.94
331_Q	337_P	0.768	0.94
323_L	338_A	0.767	0.94
153_Y	163_V	0.766	0.94
310_A	313_T	0.763	0.94
394_P	399_P	0.761	0.94
18_T	205_V	0.761	0.94
45_A	199_T	0.761	0.94
78_R	109_T	0.759	0.94
126_G	132_P	0.759	0.94
145_A	148_A	0.759	0.94
302_L	387_A	0.756	0.94
383_L	400_L	0.755	0.94
384_R	397_A	0.754	0.94
31_T	159_T	0.752	0.93
173_F	374_L	0.752	0.93
168_R	419_L	0.751	0.93
407_N	411_P	0.750	0.93
96_S	150_Q	0.749	0.93
308_L	311_P	0.749	0.93
368_F	381_I	0.749	0.93
8_L	12_D	0.748	0.93
71_E	74_T	0.747	0.93
389_A	397_A	0.746	0.93
17_N	258_S	0.743	0.93
188_L	192_A	0.742	0.93
146_A	149_A	0.742	0.93
64_D	69_G	0.742	0.93
168_R	207_S	0.741	0.93
295_N	314_P	0.740	0.93
261_G	340_M	0.737	0.93
111_T	122_R	0.736	0.93
219_R	226_N	0.735	0.93
412_F	420_A	0.735	0.93
229_I	343_L	0.734	0.93
389_A	398_L	0.730	0.92
14_K	39_I	0.730	0.92
185_G	192_A	0.730	0.92
187_P	192_A	0.729	0.92
238_R	251_S	0.727	0.92
34_L	61_I	0.726	0.92
124_V	128_N	0.724	0.92
15_A	237_R	0.720	0.92
64_D	67_G	0.715	0.92
413_L	421_T	0.714	0.92
387_A	390_L	0.712	0.92
128_N	133_P	0.711	0.91
91_Y	136_I	0.711	0.91
84_R	99_D	0.708	0.91
243_L	249_E	0.707	0.91
41_L	200_L	0.705	0.91
71_E	284_K	0.705	0.91
71_E	282_E	0.704	0.91
211_E	418_Y	0.704	0.91
128_N	131_V	0.704	0.91
97_L	147_L	0.704	0.91
171_P	200_L	0.702	0.91
115_G	118_R	0.702	0.91
214_I	217_L	0.701	0.91
331_Q	334_G	0.699	0.91
43_E	202_G	0.699	0.91
24_V	27_D	0.698	0.91
265_V	322_F	0.696	0.91
361_L	365_L	0.696	0.91
126_G	130_P	0.695	0.91
9_I	17_N	0.692	0.90
271_P	297_E	0.690	0.90
53_F	79_F	0.690	0.90
265_V	339_D	0.689	0.90
380_D	401_G	0.688	0.90
114_R	118_R	0.686	0.90
358_L	361_L	0.686	0.90
245_G	250_V	0.686	0.90
129_L	134_S	0.685	0.90
32_V	229_I	0.684	0.90
328_G	332_P	0.682	0.90
110_V	165_A	0.682	0.90
2_S	5_E	0.681	0.90
148_A	413_L	0.681	0.90
268_V	379_V	0.681	0.90
274_D	291_K	0.679	0.89
58_L	238_R	0.678	0.89
262_N	368_F	0.678	0.89
406_A	411_P	0.677	0.89
169_D	202_G	0.674	0.89
262_N	322_F	0.674	0.89
95_T	100_P	0.671	0.89
298_L	301_L	0.669	0.89
108_Y	163_V	0.668	0.89
293_V	323_L	0.667	0.89
167_Q	206_H	0.666	0.89
161_G	210_L	0.664	0.88
97_L	100_P	0.663	0.88
85_N	297_E	0.662	0.88
303_N	308_L	0.660	0.88
391_L	396_P	0.658	0.88
243_L	255_V	0.658	0.88
348_P	366_A	0.657	0.88
357_R	361_L	0.656	0.88
155_L	161_G	0.656	0.88
184_N	306_Y	0.656	0.88
32_V	217_L	0.654	0.88
244_G	250_V	0.654	0.88
330_N	335_V	0.653	0.88
63_I	229_I	0.653	0.88
132_P	167_Q	0.653	0.88
4_R	13_P	0.652	0.88
61_I	77_F	0.652	0.88
226_N	332_P	0.651	0.87
21_Y	37_N	0.650	0.87
358_L	362_G	0.648	0.87
318_L	386_V	0.646	0.87
163_V	210_L	0.645	0.87
400_L	403_G	0.644	0.87
17_N	279_N	0.644	0.87
286_D	290_A	0.642	0.87
71_E	232_W	0.640	0.87
239_Q	242_V	0.637	0.86
135_N	141_T	0.635	0.86
147_L	151_A	0.634	0.86
218_T	227_P	0.632	0.86
102_L	141_T	0.632	0.86
335_V	338_A	0.631	0.86
51_Y	167_Q	0.630	0.86
350_T	366_A	0.628	0.86
173_F	404_V	0.628	0.86
262_N	341_L	0.625	0.85
23_F	26_P	0.624	0.85
132_P	141_T	0.624	0.85
129_L	133_P	0.624	0.85
308_L	313_T	0.623	0.85
320_A	326_I	0.621	0.85
387_A	400_L	0.621	0.85
60_E	71_E	0.621	0.85
35_I	419_L	0.621	0.85
362_G	365_L	0.620	0.85
309_P	313_T	0.615	0.84
35_I	170_D	0.614	0.84
244_G	247_G	0.614	0.84
287_A	337_P	0.613	0.84
25_S	211_E	0.612	0.84
333_T	337_P	0.609	0.84
322_F	386_V	0.609	0.84
240_V	250_V	0.606	0.83
300_A	313_T	0.605	0.83
384_R	389_A	0.604	0.83
189_G	192_A	0.603	0.83
17_N	36_A	0.603	0.83
389_A	396_P	0.602	0.83
319_V	323_L	0.602	0.83
391_L	394_P	0.601	0.83
385_A	390_L	0.600	0.83
397_A	401_G	0.598	0.83
299_A	304_A	0.598	0.83
64_D	70_K	0.597	0.83
110_V	126_G	0.594	0.82
381_I	385_A	0.593	0.82
396_P	401_G	0.591	0.82
125_L	132_P	0.590	0.82
75_Y	212_V	0.590	0.82
303_N	312_T	0.589	0.82
178_A	184_N	0.589	0.82
186_A	193_A	0.589	0.82
95_T	98_D	0.588	0.82
52_E	81_T	0.587	0.81
243_L	251_S	0.584	0.81
186_A	192_A	0.584	0.81
222_A	225_T	0.584	0.81
173_F	179_I	0.583	0.81
187_P	193_A	0.582	0.81
247_G	250_V	0.582	0.81
223_S	226_N	0.581	0.81
124_V	127_T	0.580	0.81
52_E	206_H	0.580	0.81
47_G	180_F	0.574	0.80
110_V	210_L	0.574	0.80
18_T	170_D	0.573	0.80
150_Q	153_Y	0.573	0.80
42_E	167_Q	0.573	0.80
22_A	343_L	0.573	0.80
260_L	267_E	0.572	0.80
119_T	123_T	0.572	0.80
322_F	382_E	0.570	0.80
168_R	171_P	0.569	0.79
14_K	57_V	0.569	0.79
310_A	314_P	0.568	0.79
393_D	400_L	0.566	0.79
126_G	161_G	0.566	0.79
410_V	421_T	0.565	0.79
297_E	300_A	0.564	0.79
39_I	52_E	0.564	0.79
65_N	73_I	0.562	0.79
90_L	297_E	0.562	0.79
77_F	208_I	0.561	0.79
350_T	355_Q	0.556	0.78
97_L	105_R	0.556	0.78
80_K	109_T	0.556	0.78
408_D	412_F	0.554	0.78
380_D	384_R	0.553	0.78
86_P	90_L	0.553	0.78
179_I	379_V	0.553	0.78
41_L	203_F	0.553	0.78
185_G	191_N	0.552	0.77
218_T	346_A	0.551	0.77
243_L	252_G	0.551	0.77
263_P	368_F	0.550	0.77
52_E	56_D	0.550	0.77
274_D	289_F	0.550	0.77
373_R	376_D	0.546	0.77
384_R	401_G	0.545	0.77
331_Q	336_T	0.544	0.76
116_G	121_T	0.544	0.76
220_D	345_T	0.544	0.76
176_L	200_L	0.543	0.76
70_K	116_G	0.543	0.76
380_D	389_A	0.541	0.76
360_V	364_D	0.541	0.76
83_L	105_R	0.541	0.76
35_I	374_L	0.541	0.76
400_L	405_D	0.540	0.76
96_S	100_P	0.537	0.75
214_I	218_T	0.537	0.75
236_S	256_Q	0.537	0.75
184_N	191_N	0.533	0.75
123_T	126_G	0.533	0.75
87_N	292_Y	0.533	0.75
71_E	115_G	0.531	0.75
298_L	302_L	0.531	0.75
361_L	381_I	0.530	0.75
94_G	101_N	0.530	0.75
301_L	305_L	0.530	0.75
45_A	203_F	0.530	0.75
36_A	235_A	0.529	0.74
102_L	132_P	0.529	0.74
417_P	422_P	0.529	0.74
134_S	206_H	0.528	0.74
399_P	402_D	0.528	0.74
98_D	105_R	0.527	0.74
85_N	103_N	0.527	0.74
171_P	209_A	0.526	0.74
173_F	375_G	0.526	0.74
116_G	119_T	0.526	0.74
57_V	235_A	0.526	0.74
22_A	341_L	0.525	0.74
126_G	131_V	0.525	0.74
125_L	129_L	0.524	0.74
11_K	52_E	0.524	0.74
69_G	338_A	0.523	0.74
45_A	202_G	0.522	0.73
61_I	231_V	0.521	0.73
329_L	337_P	0.521	0.73
5_E	10_S	0.521	0.73
85_N	93_T	0.520	0.73
98_D	107_T	0.520	0.73
323_L	337_P	0.519	0.73
248_T	251_S	0.518	0.73
175_D	178_A	0.518	0.73
3_H	7_P	0.518	0.73
341_L	368_F	0.516	0.73
22_A	34_L	0.513	0.72
13_P	42_E	0.513	0.72
65_N	68_D	0.512	0.72
324_T	328_G	0.512	0.72
391_L	398_L	0.511	0.72
408_D	420_A	0.511	0.72
168_R	421_T	0.510	0.72
114_R	119_T	0.509	0.72
174_V	200_L	0.508	0.71
126_G	163_V	0.508	0.71
329_L	334_G	0.507	0.71
297_E	301_L	0.506	0.71
3_H	6_A	0.505	0.71
26_P	31_T	0.504	0.71
75_Y	210_L	0.501	0.70
270_I	274_D	0.501	0.70
326_I	391_L	0.501	0.70
83_L	103_N	0.500	0.70
179_I	199_T	0.500	0.70

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
2xn2A	4	0.2133	2.2	0.985	Contact Map
3af5A	1	0.1422	1.9	0.985	Contact Map
2ycbA	2	0.1422	1.8	0.985	Contact Map
2xr1A	2	0.1422	1.8	0.985	Contact Map
2yfoA	4	0.2275	1.5	0.986	Contact Map
3tguG	1	0.1185	1.5	0.986	Contact Map
1pp9G	1	0.1185	1.5	0.986	Contact Map
2znlB	1	0.0355	1.3	0.986	Contact Map
1fm0E	2	0.1185	1.1	0.987	Contact Map
3eujB	2	0.1185	1.1	0.987	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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