GREMLIN Database
YjzC - YjzC-like protein
PFAM: PF14168 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 55 (54)
Sequences: 890 (572)
Seq/√Len: 77.8
META: 0.726

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
9_P46_T2.9741.00
38_E41_D2.7171.00
18_E34_E2.2871.00
6_R52_K2.2091.00
24_P27_G2.2041.00
18_E36_T2.1821.00
7_F14_P2.0871.00
12_K42_R2.0861.00
8_K52_K1.7231.00
48_N51_R1.6311.00
7_F43_F1.5740.99
37_L43_F1.5500.99
29_V32_P1.4370.99
37_L41_D1.4350.99
7_F11_E1.3820.99
22_V54_K1.3720.99
8_K11_E1.3380.98
33_R47_S1.3310.98
13_A17_G1.3150.98
47_S51_R1.3020.98
3_E28_P1.2240.97
20_I28_P1.1970.97
16_S38_E1.1520.96
22_V52_K1.0500.93
23_G27_G1.0150.92
5_T55_K0.9890.91
16_S41_D0.9760.90
6_R24_P0.9730.90
20_I29_V0.9500.89
13_A43_F0.9440.89
13_A40_G0.9400.88
8_K45_P0.9350.88
9_P52_K0.9320.88
21_E47_S0.9130.87
21_E29_V0.9000.86
14_P40_G0.8810.85
46_T50_G0.8740.84
23_G26_G0.8500.83
42_R45_P0.8210.81
8_K50_G0.7960.78
19_Y36_T0.7880.78
32_P49_K0.7840.77
19_Y53_W0.7760.77
2_G34_E0.7710.76
21_E37_L0.7610.75
19_Y43_F0.7580.75
11_E45_P0.7450.74
17_G34_E0.7390.73
35_V43_F0.7250.72
14_P54_K0.7250.72
7_F15_N0.7200.71
17_G22_V0.6760.66
2_G5_T0.6630.65
20_I34_E0.6590.64
21_E51_R0.6560.64
5_T20_I0.6440.63
14_P31_N0.6380.62
9_P55_K0.6330.61
5_T54_K0.6240.60
39_K42_R0.6100.58
21_E46_T0.6100.58
3_E6_R0.6070.58
21_E32_P0.5860.55
31_N49_K0.5840.55
11_E54_K0.5810.55
1_M40_G0.5660.53
7_F38_E0.5620.52
6_R22_V0.5610.52
16_S36_T0.5520.51
13_A36_T0.5440.50
40_G48_N0.5400.50
33_R37_L0.5370.49
31_N39_K0.5300.48
37_L42_R0.5270.48
25_R30_N0.5220.47
11_E14_P0.5210.47
9_P51_R0.5120.46
13_A38_E0.5100.46
23_G33_R0.5070.45
13_A16_S0.5040.45
9_P50_G0.5000.45
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3wnoA 2 1 4.1 0.883 Contact Map
1mscA 2 0.3091 3.7 0.885 Contact Map
2vtuJ 14 0.3091 3.6 0.885 Contact Map
2pn5A 1 1 3.3 0.888 Contact Map
2x41A 1 0.7636 3.2 0.889 Contact Map
4acqA 4 0.9636 3 0.89 Contact Map
1unaA 2 0.3273 2.6 0.894 Contact Map
4fxkA 1 0.9636 2.4 0.896 Contact Map
4bbjA 1 0.8727 2.3 0.897 Contact Map
3cu7A 2 0.9636 2.2 0.897 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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