GREMLIN Database
Phage_gp49_66 - Phage protein (N4 Gp49/phage Sf6 gene 66) family
PFAM: PF13876 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 80 (78)
Sequences: 2769 (1895)
Seq/√Len: 214.6
META: 0.891

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
53_A57_R2.6801.00
7_E65_V2.6031.00
13_E61_R2.5431.00
58_K62_E2.2901.00
75_L78_E2.2171.00
67_K70_P2.0361.00
5_D8_A1.9651.00
42_E67_K1.9571.00
4_E8_A1.9451.00
9_N72_E1.8631.00
72_E75_L1.7961.00
55_I59_I1.7121.00
63_N66_N1.7111.00
9_N34_R1.6931.00
6_I68_I1.5921.00
5_D9_N1.4591.00
62_E66_N1.4411.00
26_L38_T1.4371.00
3_P7_E1.4211.00
14_E32_T1.3981.00
30_V38_T1.3701.00
33_L68_I1.3561.00
11_A34_R1.3541.00
54_E58_K1.3331.00
55_I58_K1.3321.00
42_E63_N1.3261.00
26_L30_V1.2831.00
54_E57_R1.2631.00
3_P65_V1.2531.00
46_A77_K1.2381.00
61_R65_V1.2301.00
19_P24_T1.1751.00
75_L79_K1.1211.00
47_S50_N1.0571.00
29_C61_R1.0371.00
4_E7_E1.0321.00
9_N75_L1.0271.00
9_N74_Y1.0241.00
46_A76_L1.0161.00
39_V71_L1.0161.00
13_E31_L1.0151.00
12_S32_T1.0101.00
9_N78_E0.9991.00
25_T77_K0.9971.00
37_F44_A0.9891.00
26_L40_T0.9861.00
28_V40_T0.9681.00
18_A30_V0.9671.00
26_L42_E0.9581.00
1_V5_D0.9561.00
41_G60_A0.9521.00
5_D72_E0.9400.99
31_L64_A0.9220.99
69_W73_G0.9210.99
59_I62_E0.9170.99
30_V40_T0.8990.99
14_E18_A0.8790.99
16_F19_P0.8480.99
32_T38_T0.8330.99
41_G64_A0.8280.99
41_G63_N0.8250.99
27_T51_F0.8180.99
37_F70_P0.7950.98
25_T45_C0.7900.98
20_D24_T0.7880.98
14_E20_D0.7810.98
15_Y61_R0.7700.98
15_Y29_C0.7660.98
16_F21_G0.7520.98
29_C60_A0.7480.97
2_T5_D0.7470.97
31_L61_R0.7450.97
7_E61_R0.7440.97
50_N76_L0.7410.97
16_F28_V0.7110.97
39_V68_I0.7090.97
15_Y57_R0.7060.96
16_F30_V0.7010.96
38_T45_C0.6880.96
16_F20_D0.6850.96
17_T57_R0.6820.96
62_E65_V0.6790.96
27_T60_A0.6720.95
26_L44_A0.6670.95
25_T48_P0.6590.95
17_T53_A0.6520.95
18_A26_L0.6510.94
63_N67_K0.6500.94
59_I63_N0.6490.94
18_A28_V0.6470.94
73_G76_L0.6420.94
42_E45_C0.6370.94
6_I72_E0.6290.93
18_A21_G0.6140.93
45_C51_F0.6070.92
37_F43_S0.5910.91
14_E21_G0.5890.91
29_C57_R0.5880.91
10_I13_E0.5790.90
10_I65_V0.5760.90
9_N33_L0.5730.90
52_D55_I0.5710.90
18_A24_T0.5590.89
25_T38_T0.5440.87
42_E60_A0.5410.87
50_N69_W0.5390.87
29_C64_A0.5360.87
68_I72_E0.5160.84
37_F71_L0.5150.84
16_F24_T0.5140.84
60_A64_A0.5120.84
37_F46_A0.5090.84
45_C77_K0.5080.83
42_E70_P0.5040.83
25_T46_A0.5030.83
17_T21_G0.5000.83
17_T20_D0.5000.83
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2pw9A 2 0.775 8.9 0.902 Contact Map
2fggA 2 0.9375 8.8 0.902 Contact Map
4pdeA 2 0.7 8.5 0.903 Contact Map
1v5eA 4 0.95 6.5 0.908 Contact Map
2jn4A 1 0.6 5.2 0.912 Contact Map
4kgdA 4 0.9375 5.2 0.912 Contact Map
4wpyA 2 0.9125 4.7 0.914 Contact Map
3cuqA 1 0.7 4.6 0.914 Contact Map
4espA 1 0.925 4.4 0.915 Contact Map
4v2xA 2 0.5375 4.3 0.915 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0051 seconds.