DUF4127 - PFAM28P - GREMLIN Contacts

Home
GREMLIN
- Submit - Monomer
- Submit - Complex
Contacts
Metagenomics
- Contacts
- Structures
Structures
- List
Old Projects
- Complexes (2014)
- PFAM (2013)

DUF4127 - Protein of unknown function (DUF4127)

PFAM:	PF13552	Sequences: ILLVPLDDRPVNYDFPVMLAAIAGIEVVTPPRELLGNKKTPGDPDALWEWLLENAPDADAAVISLDMLLYGGLVPSRLHHLSLEELLERLERLRELKKANPNLKIYAFSTIMRLPPTSSSEEEPDYYAEYGREIFRYSYLLDKAELGGLTPEERAELAALEAEIPAEVLEDYLARRARNLAVNLALLDLVKEGVIDYLVIGQDDSAPYGLTAMEQRKLRALIAELGLEDRVLIYPGADEVGLTLLARALNDLAGYKPRVYVRYSSPDGPDTIPPYEDRPLGETVKEHIRAAGGRLVDSPEEADLVLAVNTPGDKQGEERNLKEFVDAIKEYLAAGKPVALADVAYANGADNALVELLLKRGLLDKLAAYAGWNTAGNTLGTALAQGVLALLAGTGDEAAHLEFLLLRYLDDWAYQANVRPELNAELLPAGGDPYLLYFDLDEAEAEVEERLRERLQRFAAELLPGSPFRIEIEVSLPWNRMFEIDIE	Download Alignment We filter this alignment to remove sites that have many gaps before running GREMLIN. Date: 2015_10
Length:	487 (485)
Sequences:	1090 (941)
Seq/√Len:	42.7
META:	0.656

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:

i	j	Sco	Prob
339_A	386_G	6.137	1.00
136_R	156_E	5.499	1.00
288_I	293_G	4.807	1.00
94_R	192_E	4.205	1.00
43_D	46_A	3.806	1.00
65_L	186_L	3.516	1.00
3_L	241_G	3.383	1.00
382_A	386_G	3.247	1.00
65_L	107_A	3.237	1.00
191_K	225_L	3.143	1.00
291_A	383_L	3.043	1.00
475_S	485_D	3.003	1.00
201_G	240_V	2.996	1.00
329_K	360_R	2.872	1.00
62_V	245_L	2.839	1.00
293_G	387_V	2.728	1.00
133_E	163_E	2.683	1.00
14_D	485_D	2.678	1.00
180_L	214_E	2.651	1.00
142_D	216_R	2.649	1.00
69_L	182_V	2.648	1.00
304_L	386_G	2.646	1.00
48_W	92_R	2.638	1.00
124_P	175_R	2.556	1.00
185_A	188_D	2.498	1.00
340_L	366_L	2.490	1.00
34_L	46_A	2.467	1.00
109_S	183_N	2.464	1.00
339_A	382_A	2.455	1.00
60_A	248_A	2.452	1.00
341_A	378_T	2.443	1.00
118_S	133_E	2.323	1.00
381_T	403_F	2.314	1.00
107_A	195_I	2.293	1.00
91_E	94_R	2.275	1.00
259_V	288_I	2.259	1.00
222_I	231_V	2.255	1.00
274_P	346_A	2.244	1.00
259_V	304_L	2.223	1.00
52_L	92_R	2.219	1.00
134_I	169_L	2.214	1.00
423_N	481_M	2.208	1.00
280_L	343_V	2.122	0.99
142_D	146_L	2.113	0.99
20_A	27_V	2.094	0.99
2_L	61_A	2.092	0.99
145_E	213_M	2.066	0.99
19_L	388_L	2.037	0.99
480_R	483_E	2.036	0.99
130_Y	165_P	2.020	0.99
2_L	58_A	2.015	0.99
160_L	164_I	2.014	0.99
173_L	210_L	1.994	0.99
440_L	479_N	1.993	0.99
13_Y	29_T	1.974	0.99
407_R	411_D	1.973	0.99
126_Y	131_G	1.968	0.99
269_P	281_G	1.965	0.99
260_Y	302_A	1.957	0.99
258_R	296_V	1.949	0.99
61_A	103_L	1.927	0.99
73_L	110_T	1.878	0.99
70_Y	112_M	1.861	0.99
410_D	415_Q	1.860	0.99
97_K	196_D	1.856	0.99
261_V	295_L	1.828	0.98
17_V	29_T	1.820	0.98
283_T	376_G	1.815	0.98
268_G	310_T	1.813	0.98
137_Y	169_L	1.804	0.98
61_A	105_I	1.801	0.98
184_L	221_L	1.797	0.98
305_V	331_Y	1.795	0.98
15_F	403_F	1.772	0.98
64_S	67_M	1.754	0.98
403_F	407_R	1.749	0.98
284_V	308_V	1.746	0.98
370_A	381_T	1.745	0.98
52_L	95_E	1.733	0.98
115_P	175_R	1.728	0.98
370_A	407_R	1.719	0.98
82_S	85_E	1.708	0.97
190_V	231_V	1.708	0.97
150_T	153_E	1.707	0.97
2_L	51_L	1.685	0.97
188_D	221_L	1.667	0.97
20_A	62_V	1.662	0.97
258_R	294_R	1.653	0.97
144_A	157_L	1.639	0.97
236_G	239_E	1.627	0.97
2_L	54_N	1.625	0.97
451_L	455_L	1.624	0.97
250_N	387_V	1.624	0.97
427_L	430_G	1.623	0.97
94_R	189_L	1.614	0.96
261_V	284_V	1.606	0.96
349_A	369_Y	1.579	0.96
385_Q	400_H	1.571	0.96
187_L	227_L	1.563	0.96
11_V	15_F	1.560	0.96
275_Y	346_A	1.555	0.96
341_A	382_A	1.554	0.96
193_G	230_R	1.551	0.95
8_D	36_G	1.544	0.95
374_T	377_N	1.536	0.95
28_V	54_N	1.524	0.95
48_W	52_L	1.517	0.95
326_D	360_R	1.514	0.95
262_R	327_A	1.509	0.95
6_L	12_N	1.498	0.95
93_L	194_V	1.489	0.94
114_L	138_S	1.482	0.94
307_A	324_F	1.473	0.94
52_L	99_A	1.455	0.94
69_L	86_L	1.428	0.93
137_Y	141_L	1.417	0.93
112_M	175_R	1.412	0.93
477_P	480_R	1.411	0.93
165_P	168_V	1.410	0.93
60_A	106_Y	1.400	0.92
55_A	103_L	1.394	0.92
370_A	378_T	1.392	0.92
304_L	390_L	1.390	0.92
8_D	32_R	1.389	0.92
123_E	203_D	1.385	0.92
246_A	384_A	1.372	0.91
444_E	479_N	1.367	0.91
358_L	363_L	1.366	0.91
458_F	462_L	1.364	0.91
451_L	476_L	1.357	0.91
260_Y	305_V	1.348	0.91
205_S	211_T	1.339	0.90
95_E	99_A	1.324	0.90
309_N	324_F	1.314	0.90
201_G	234_Y	1.311	0.89
130_Y	164_I	1.311	0.89
349_A	412_W	1.305	0.89
214_E	218_L	1.304	0.89
110_T	237_A	1.296	0.89
351_N	412_W	1.295	0.89
5_P	9_R	1.293	0.89
454_R	457_R	1.288	0.89
137_Y	164_I	1.286	0.89
175_R	273_P	1.285	0.89
259_V	293_G	1.280	0.88
60_A	104_K	1.277	0.88
111_I	200_I	1.277	0.88
95_E	98_K	1.275	0.88
343_V	378_T	1.272	0.88
280_L	310_T	1.270	0.88
282_E	285_K	1.270	0.88
158_A	161_E	1.267	0.88
205_S	276_E	1.258	0.87
339_A	368_A	1.247	0.87
304_L	383_L	1.243	0.87
275_Y	317_E	1.239	0.87
87_L	182_V	1.225	0.86
202_Q	209_G	1.224	0.86
70_Y	179_N	1.223	0.86
8_D	39_K	1.214	0.85
477_P	483_E	1.211	0.85
476_L	484_I	1.206	0.85
268_G	311_P	1.203	0.85
49_E	53_E	1.197	0.85
351_N	417_N	1.193	0.84
156_E	159_A	1.193	0.84
176_R	214_E	1.184	0.84
117_T	175_R	1.182	0.84
114_L	211_T	1.167	0.83
132_R	136_R	1.164	0.83
221_L	224_E	1.162	0.83
97_K	103_L	1.157	0.83
324_F	328_I	1.152	0.82
410_D	413_A	1.146	0.82
126_Y	171_D	1.143	0.82
116_P	135_F	1.137	0.81
370_A	382_A	1.135	0.81
240_V	287_H	1.134	0.81
143_K	208_Y	1.129	0.81
202_Q	205_S	1.121	0.81
258_R	303_D	1.120	0.80
122_E	239_E	1.118	0.80
104_K	251_D	1.114	0.80
115_P	127_Y	1.108	0.80
66_D	108_F	1.108	0.80
94_R	194_V	1.106	0.80
140_L	157_L	1.102	0.79
54_N	57_D	1.094	0.79
149_L	153_E	1.094	0.79
140_L	160_L	1.091	0.79
81_L	89_R	1.090	0.79
86_L	182_V	1.084	0.78
12_N	241_G	1.083	0.78
64_S	108_F	1.082	0.78
135_F	142_D	1.080	0.78
325_V	356_L	1.080	0.78
239_E	377_N	1.078	0.78
415_Q	419_R	1.074	0.78
115_P	135_F	1.072	0.77
332_L	366_L	1.070	0.77
304_L	339_A	1.069	0.77
51_L	63_I	1.067	0.77
447_V	476_L	1.067	0.77
7_D	10_P	1.067	0.77
116_P	203_D	1.066	0.77
303_D	337_P	1.066	0.77
123_E	171_D	1.065	0.77
55_A	58_A	1.064	0.77
372_W	377_N	1.062	0.77
266_P	269_P	1.060	0.77
46_A	49_E	1.059	0.77
299_P	302_A	1.054	0.76
159_A	163_E	1.054	0.76
307_A	328_I	1.054	0.76
15_F	381_T	1.050	0.76
175_R	211_T	1.047	0.76
201_G	215_Q	1.043	0.75
35_L	67_M	1.041	0.75
123_E	131_G	1.039	0.75
368_A	382_A	1.033	0.75
47_L	67_M	1.030	0.75
131_G	135_F	1.028	0.74
199_V	290_A	1.027	0.74
189_L	194_V	1.026	0.74
18_M	406_L	1.020	0.74
478_W	483_E	1.018	0.74
115_P	203_D	1.018	0.74
373_N	377_N	1.017	0.74
6_L	16_P	1.014	0.73
333_A	365_K	1.013	0.73
221_L	225_L	1.009	0.73
262_R	331_Y	1.007	0.73
302_A	305_V	1.006	0.73
412_W	415_Q	1.006	0.73
304_L	387_V	1.001	0.72
197_Y	247_R	0.997	0.72
426_L	430_G	0.990	0.72
400_H	404_L	0.987	0.71
259_V	383_L	0.986	0.71
371_G	378_T	0.984	0.71
325_V	340_L	0.983	0.71
264_S	309_N	0.981	0.71
187_L	231_V	0.978	0.71
246_A	250_N	0.977	0.71
328_I	340_L	0.973	0.70
115_P	211_T	0.972	0.70
135_F	139_Y	0.972	0.70
403_F	406_L	0.971	0.70
455_L	458_F	0.969	0.70
436_L	440_L	0.968	0.70
3_L	16_P	0.967	0.70
280_L	379_L	0.966	0.70
142_D	208_Y	0.962	0.69
83_L	181_A	0.961	0.69
242_L	384_A	0.960	0.69
108_F	241_G	0.956	0.69
444_E	448_E	0.954	0.69
478_W	482_F	0.945	0.68
111_I	183_N	0.944	0.68
79_H	175_R	0.943	0.68
347_N	415_Q	0.942	0.68
115_P	124_P	0.942	0.68
222_I	233_I	0.940	0.68
18_M	21_A	0.940	0.68
100_N	104_K	0.938	0.67
2_L	55_A	0.933	0.67
187_L	200_I	0.927	0.66
2_L	28_V	0.926	0.66
288_I	295_L	0.925	0.66
309_N	350_D	0.925	0.66
1_I	245_L	0.921	0.66
120_S	125_D	0.918	0.66
379_L	383_L	0.917	0.66
6_L	9_R	0.917	0.66
263_Y	269_P	0.915	0.65
452_R	456_Q	0.915	0.65
261_V	306_L	0.912	0.65
202_Q	211_T	0.911	0.65
348_G	419_R	0.910	0.65
443_A	451_L	0.908	0.65
188_D	192_E	0.903	0.64
171_D	350_D	0.901	0.64
72_G	75_P	0.901	0.64
458_F	463_L	0.900	0.64
245_L	383_L	0.899	0.64
237_A	276_E	0.895	0.64
137_Y	161_E	0.894	0.64
171_D	203_D	0.893	0.64
459_A	463_L	0.892	0.63
4_V	47_L	0.892	0.63
37_N	40_T	0.888	0.63
204_D	377_N	0.887	0.63
222_I	227_L	0.887	0.63
234_Y	276_E	0.885	0.63
450_R	453_E	0.885	0.63
180_L	183_N	0.883	0.63
347_N	371_G	0.883	0.63
65_L	109_S	0.882	0.63
438_F	451_L	0.882	0.63
377_N	380_G	0.879	0.62
420_P	424_A	0.878	0.62
202_Q	381_T	0.875	0.62
437_Y	481_M	0.874	0.62
354_V	412_W	0.873	0.62
3_L	12_N	0.872	0.62
446_E	449_E	0.872	0.62
4_V	63_I	0.871	0.62
73_L	76_S	0.869	0.61
124_P	131_G	0.868	0.61
115_P	176_R	0.863	0.61
122_E	126_Y	0.861	0.61
110_T	241_G	0.857	0.60
440_L	451_L	0.854	0.60
176_R	287_H	0.854	0.60
4_V	68_L	0.852	0.60
300_E	305_V	0.852	0.60
195_I	198_L	0.849	0.60
2_L	57_D	0.849	0.60
249_L	388_L	0.848	0.60
87_L	185_A	0.847	0.59
112_M	176_R	0.846	0.59
136_R	140_L	0.842	0.59
276_E	376_G	0.837	0.59
35_L	279_P	0.837	0.59
234_Y	240_V	0.830	0.58
225_L	290_A	0.830	0.58
170_E	174_A	0.830	0.58
66_D	107_A	0.830	0.58
127_Y	347_N	0.827	0.58
143_K	147_G	0.827	0.58
116_P	132_R	0.826	0.57
47_L	98_K	0.824	0.57
171_D	175_R	0.823	0.57
6_L	200_I	0.819	0.57
449_E	453_E	0.814	0.56
374_T	482_F	0.813	0.56
66_D	110_T	0.811	0.56
79_H	178_R	0.810	0.56
118_S	131_G	0.808	0.56
211_T	273_P	0.808	0.56
86_L	178_R	0.808	0.56
131_G	175_R	0.808	0.56
32_R	485_D	0.808	0.56
122_E	131_G	0.807	0.56
56_P	100_N	0.806	0.56
368_A	385_Q	0.805	0.56
21_A	26_E	0.804	0.55
421_E	454_R	0.799	0.55
143_K	150_T	0.799	0.55
110_T	235_P	0.798	0.55
176_R	235_P	0.798	0.55
172_Y	202_Q	0.798	0.55
438_F	455_L	0.797	0.55
277_D	309_N	0.796	0.55
12_N	234_Y	0.795	0.55
47_L	328_I	0.794	0.54
116_P	131_G	0.794	0.54
124_P	211_T	0.793	0.54
8_D	12_N	0.793	0.54
410_D	419_R	0.791	0.54
187_L	198_L	0.788	0.54
135_F	277_D	0.788	0.54
193_G	198_L	0.784	0.54
237_A	376_G	0.784	0.54
36_G	122_E	0.779	0.53
307_A	327_A	0.779	0.53
183_N	240_V	0.777	0.53
276_E	347_N	0.774	0.53
59_D	369_Y	0.773	0.53
127_Y	131_G	0.773	0.53
111_I	375_A	0.773	0.53
389_A	400_H	0.770	0.52
123_E	126_Y	0.769	0.52
343_V	375_A	0.769	0.52
367_A	385_Q	0.767	0.52
249_L	391_L	0.766	0.52
151_P	154_R	0.765	0.52
349_A	416_A	0.765	0.52
124_P	273_P	0.765	0.52
30_P	50_W	0.760	0.51
190_V	195_I	0.758	0.51
112_M	202_Q	0.755	0.51
477_P	482_F	0.755	0.51
5_P	10_P	0.755	0.51
184_L	188_D	0.754	0.51
278_R	282_E	0.754	0.51
131_G	171_D	0.749	0.50
42_G	67_M	0.748	0.50
106_Y	197_Y	0.748	0.50
264_S	324_F	0.746	0.50
294_R	330_E	0.744	0.50
215_Q	278_R	0.744	0.50
440_L	444_E	0.743	0.50
211_T	214_E	0.740	0.49
260_Y	299_P	0.740	0.49
285_K	295_L	0.740	0.49
356_L	360_R	0.740	0.49
211_T	376_G	0.739	0.49
196_D	251_D	0.738	0.49
121_E	243_T	0.736	0.49
115_P	214_E	0.735	0.49
36_G	67_M	0.735	0.49
30_P	47_L	0.734	0.49
368_A	400_H	0.731	0.49
450_R	454_R	0.730	0.48
179_N	214_E	0.729	0.48
427_L	431_G	0.727	0.48
243_T	291_A	0.726	0.48
306_L	383_L	0.726	0.48
123_E	135_F	0.725	0.48
243_T	290_A	0.725	0.48
275_Y	345_Y	0.725	0.48
287_H	290_A	0.724	0.48
121_E	438_F	0.723	0.48
262_R	307_A	0.723	0.48
197_Y	232_L	0.722	0.48
207_P	385_Q	0.721	0.48
117_T	124_P	0.721	0.48
1_I	323_E	0.721	0.48
234_Y	287_H	0.720	0.47
321_L	324_F	0.719	0.47
203_D	240_V	0.716	0.47
237_A	240_V	0.715	0.47
202_Q	215_Q	0.714	0.47
89_R	419_R	0.714	0.47
378_T	383_L	0.713	0.47
114_L	205_S	0.711	0.47
280_L	284_V	0.710	0.47
203_D	211_T	0.709	0.46
25_I	253_A	0.706	0.46
340_L	353_L	0.705	0.46
366_L	404_L	0.704	0.46
28_V	47_L	0.704	0.46
157_L	233_I	0.703	0.46
8_D	38_K	0.700	0.46
377_N	482_F	0.699	0.46
137_Y	157_L	0.696	0.45
331_Y	338_V	0.694	0.45
112_M	205_S	0.693	0.45
421_E	450_R	0.692	0.45
188_D	225_L	0.692	0.45
306_L	341_A	0.685	0.44
131_G	347_N	0.684	0.44
325_V	332_L	0.683	0.44
36_G	209_G	0.680	0.44
188_D	420_P	0.680	0.44
118_S	211_T	0.679	0.44
137_Y	173_L	0.677	0.43
288_I	296_V	0.677	0.43
83_L	87_L	0.676	0.43
309_N	321_L	0.675	0.43
193_G	196_D	0.673	0.43
38_K	119_S	0.673	0.43
273_P	344_A	0.670	0.43
131_G	142_D	0.670	0.43
220_A	224_E	0.669	0.43
50_W	368_A	0.668	0.43
437_Y	441_D	0.667	0.43
97_K	105_I	0.667	0.43
404_L	408_Y	0.666	0.42
62_V	469_R	0.665	0.42
301_E	336_K	0.665	0.42
382_A	422_L	0.665	0.42
273_P	283_T	0.664	0.42
426_L	431_G	0.663	0.42
40_T	57_D	0.662	0.42
67_M	75_P	0.662	0.42
91_E	185_A	0.660	0.42
91_E	181_A	0.660	0.42
339_A	383_L	0.658	0.42
293_G	383_L	0.658	0.42
436_L	439_D	0.654	0.41
166_A	170_E	0.654	0.41
114_L	172_Y	0.653	0.41
451_L	454_R	0.653	0.41
311_P	347_N	0.653	0.41
325_V	329_K	0.652	0.41
403_F	476_L	0.651	0.41
97_K	101_P	0.651	0.41
172_Y	486_I	0.651	0.41
280_L	385_Q	0.651	0.41
437_Y	443_A	0.649	0.41
64_S	74_V	0.648	0.41
114_L	201_G	0.645	0.41
15_F	410_D	0.645	0.41
105_I	194_V	0.645	0.41
451_L	463_L	0.644	0.40
266_P	324_F	0.643	0.40
91_E	453_E	0.643	0.40
46_A	449_E	0.643	0.40
78_L	124_P	0.641	0.40
126_Y	203_D	0.641	0.40
256_K	294_R	0.640	0.40
8_D	41_P	0.640	0.40
288_I	354_V	0.639	0.40
51_L	58_A	0.639	0.40
205_S	277_D	0.636	0.40
204_D	374_T	0.636	0.40
446_E	455_L	0.636	0.40
113_R	204_D	0.636	0.40
27_V	49_E	0.634	0.40
11_V	110_T	0.633	0.39
164_I	169_L	0.633	0.39
181_A	184_L	0.630	0.39
96_L	103_L	0.628	0.39
75_P	195_I	0.628	0.39
234_Y	376_G	0.628	0.39
143_K	338_V	0.628	0.39
202_Q	277_D	0.627	0.39
337_P	386_G	0.625	0.39
38_K	121_E	0.624	0.39
235_P	276_E	0.624	0.39
19_L	209_G	0.623	0.39
108_F	242_L	0.623	0.39
227_L	230_R	0.622	0.38
409_L	418_V	0.622	0.38
36_G	176_R	0.622	0.38
353_L	408_Y	0.621	0.38
114_L	210_L	0.619	0.38
180_L	184_L	0.619	0.38
135_F	206_A	0.618	0.38
159_A	340_L	0.616	0.38
442_E	445_A	0.615	0.38
117_T	201_G	0.615	0.38
362_L	408_Y	0.614	0.38
198_L	222_I	0.614	0.38
15_F	407_R	0.613	0.38
112_M	277_D	0.613	0.38
259_V	387_V	0.613	0.38
291_A	362_L	0.611	0.37
95_E	256_K	0.610	0.37
121_E	206_A	0.610	0.37
345_Y	475_S	0.610	0.37
42_G	209_G	0.609	0.37
436_L	455_L	0.609	0.37
137_Y	210_L	0.607	0.37
36_G	117_T	0.606	0.37
126_Y	135_F	0.604	0.37
344_A	350_D	0.603	0.37
24_G	245_L	0.603	0.37
158_A	336_K	0.602	0.37
406_L	410_D	0.601	0.37
59_D	102_N	0.600	0.36
184_L	217_K	0.600	0.36
68_L	370_A	0.599	0.36
81_L	86_L	0.599	0.36
223_A	228_E	0.599	0.36
207_P	277_D	0.598	0.36
346_A	371_G	0.597	0.36
426_L	481_M	0.597	0.36
38_K	476_L	0.597	0.36
45_D	92_R	0.597	0.36
122_E	127_Y	0.596	0.36
42_G	48_W	0.596	0.36
109_S	200_I	0.596	0.36
376_G	379_L	0.595	0.36
401_L	484_I	0.594	0.36
122_E	171_D	0.593	0.36
121_E	172_Y	0.593	0.36
104_K	196_D	0.592	0.36
110_T	381_T	0.592	0.36
243_T	375_A	0.592	0.36
465_G	468_F	0.592	0.36
4_V	51_L	0.591	0.36
22_I	25_I	0.591	0.36
357_L	363_L	0.591	0.36
42_G	409_L	0.591	0.36
65_L	110_T	0.590	0.36
189_L	192_E	0.590	0.36
210_L	343_V	0.590	0.36
422_L	447_V	0.590	0.36
348_G	416_A	0.589	0.36
8_D	11_V	0.589	0.36
401_L	408_Y	0.589	0.36
438_F	443_A	0.587	0.35
175_R	212_A	0.587	0.35
144_A	154_R	0.586	0.35
175_R	203_D	0.586	0.35
381_T	406_L	0.586	0.35
11_V	78_L	0.586	0.35
358_L	462_L	0.585	0.35
63_I	93_L	0.585	0.35
123_E	211_T	0.584	0.35
278_R	286_E	0.584	0.35
143_K	149_L	0.584	0.35
82_S	461_E	0.583	0.35
235_P	378_T	0.582	0.35
75_P	78_L	0.581	0.35
3_L	378_T	0.581	0.35
107_A	198_L	0.580	0.35
307_A	331_Y	0.580	0.35
454_R	458_F	0.580	0.35
48_W	96_L	0.578	0.35
237_A	278_R	0.577	0.34
292_G	341_A	0.577	0.34
47_L	448_E	0.576	0.34
283_T	287_H	0.576	0.34
36_G	74_V	0.574	0.34
260_Y	336_K	0.574	0.34
366_L	408_Y	0.574	0.34
79_H	115_P	0.574	0.34
448_E	455_L	0.572	0.34
263_Y	280_L	0.572	0.34
304_L	367_A	0.570	0.34
85_E	88_E	0.569	0.34
66_D	109_S	0.568	0.34
58_A	61_A	0.568	0.34
169_L	173_L	0.567	0.34
155_A	158_A	0.567	0.34
44_P	81_L	0.566	0.34
311_P	378_T	0.566	0.34
209_G	375_A	0.565	0.33
141_L	144_A	0.565	0.33
204_D	238_D	0.564	0.33
421_E	425_E	0.563	0.33
161_E	166_A	0.563	0.33
175_R	410_D	0.562	0.33
35_L	73_L	0.561	0.33
140_L	164_I	0.561	0.33
162_A	300_E	0.561	0.33
425_E	428_P	0.561	0.33
98_K	288_I	0.560	0.33
239_E	374_T	0.559	0.33
244_L	350_D	0.558	0.33
399_A	402_E	0.558	0.33
108_F	306_L	0.558	0.33
419_R	477_P	0.558	0.33
220_A	424_A	0.556	0.33
423_N	426_L	0.556	0.33
215_Q	311_P	0.555	0.33
115_P	131_G	0.555	0.33
114_L	202_Q	0.555	0.33
302_A	336_K	0.554	0.33
299_P	305_V	0.554	0.33
95_E	312_G	0.552	0.32
422_L	476_L	0.552	0.32
45_D	89_R	0.552	0.32
12_N	110_T	0.551	0.32
87_L	188_D	0.550	0.32
201_G	235_P	0.550	0.32
288_I	349_A	0.550	0.32
13_Y	16_P	0.549	0.32
135_F	175_R	0.549	0.32
159_A	174_A	0.549	0.32
362_L	365_K	0.548	0.32
209_G	276_E	0.548	0.32
204_D	372_W	0.548	0.32
10_P	16_P	0.548	0.32
469_R	486_I	0.547	0.32
176_R	276_E	0.547	0.32
43_D	198_L	0.546	0.32
71_G	77_R	0.546	0.32
455_L	459_A	0.546	0.32
110_T	242_L	0.546	0.32
161_E	169_L	0.545	0.32
367_A	400_H	0.545	0.32
11_V	273_P	0.544	0.32
131_G	203_D	0.544	0.32
74_V	115_P	0.543	0.32
224_E	368_A	0.543	0.32
235_P	277_D	0.543	0.32
412_W	417_N	0.542	0.32
216_R	219_R	0.542	0.32
179_N	211_T	0.542	0.32
263_Y	281_G	0.542	0.32
15_F	36_G	0.541	0.31
260_Y	331_Y	0.541	0.31
155_A	383_L	0.541	0.31
449_E	452_R	0.540	0.31
115_P	273_P	0.537	0.31
102_N	158_A	0.537	0.31
7_D	12_N	0.536	0.31
74_V	117_T	0.536	0.31
63_I	409_L	0.535	0.31
113_R	372_W	0.535	0.31
212_A	410_D	0.535	0.31
258_R	334_A	0.534	0.31
118_S	132_R	0.534	0.31
228_E	352_A	0.534	0.31
50_W	349_A	0.533	0.31
124_P	203_D	0.532	0.31
97_K	104_K	0.532	0.31
250_N	293_G	0.531	0.31
201_G	277_D	0.531	0.31
4_V	48_W	0.531	0.31
257_P	292_G	0.529	0.30
317_E	346_A	0.529	0.30
15_F	22_I	0.529	0.30
325_V	360_R	0.527	0.30
382_A	404_L	0.525	0.30
124_P	212_A	0.525	0.30
397_E	400_H	0.523	0.30
33_E	56_P	0.523	0.30
110_T	138_S	0.522	0.30
54_N	58_A	0.521	0.30
355_E	359_K	0.521	0.30
114_L	214_E	0.521	0.30
25_I	249_L	0.520	0.30
447_V	450_R	0.520	0.30
293_G	296_V	0.518	0.30
177_A	187_L	0.517	0.30
51_L	61_A	0.517	0.30
171_D	348_G	0.516	0.29
276_E	378_T	0.515	0.29
264_S	268_G	0.513	0.29
51_L	93_L	0.513	0.29
66_D	74_V	0.513	0.29
468_F	471_E	0.512	0.29
22_I	403_F	0.512	0.29
197_Y	278_R	0.512	0.29
9_R	12_N	0.512	0.29
8_D	37_N	0.511	0.29
31_P	34_L	0.511	0.29
135_F	138_S	0.511	0.29
180_L	211_T	0.509	0.29
113_R	373_N	0.508	0.29
14_D	18_M	0.507	0.29
156_E	160_L	0.507	0.29
144_A	149_L	0.505	0.29
131_G	176_R	0.504	0.29
337_P	367_A	0.504	0.29
267_D	359_K	0.503	0.28
12_N	276_E	0.501	0.28
109_S	182_V	0.501	0.28
332_L	365_K	0.500	0.28
204_D	373_N	0.500	0.28
280_L	375_A	0.500	0.28
124_P	315_Q	0.500	0.28

Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

Text file of predictions (all 3L/2 predictions)
Generate restraints for ROSETTA Structure Modeling
Upload PDB model overlay contacts on the model

HHsearch Results:

Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.

PDB	Chains	Cov	%	HHΔ
3gfsA	5	0.3409	40.3	0.976	Contact Map
2yxgA	3	0.5216	39.8	0.976	Contact Map
2yxbA	1	0.269	34.7	0.977	Contact Map
1f6kA	3	0.5585	34.6	0.977	Contact Map
4ptzC	4	0.3532	32.8	0.977	Contact Map
4r3uC	1	0.2546	32.7	0.977	Contact Map
3w7aA	2	0.3573	30.1	0.978	Contact Map
4n4pA	3	0.5544	24.1	0.979	Contact Map
2fz5A	1	0.2587	22.6	0.979	Contact Map
2dahA	1	0.1068	21.3	0.979	Contact Map

Sequence Conservation (Image Generated using WebLogo v3)

Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0135 seconds.