GREMLIN Database
Phage_TAC_12 - Phage tail assembly chaperone protein, TAC
PFAM: PF12363 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 111 (110)
Sequences: 517 (433)
Seq/√Len: 41.3
META: 0.576

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
19_R74_E3.6281.00
88_K92_E3.6011.00
11_L57_I3.3741.00
78_E102_F3.2591.00
87_E105_K3.2291.00
28_E33_K2.8521.00
26_S33_K2.5601.00
1_E8_E2.4501.00
22_D49_D2.4211.00
5_N72_D2.3831.00
24_K55_D2.3111.00
61_T68_P2.2531.00
21_L41_L1.9960.99
69_S72_D1.8630.98
41_L56_V1.7870.98
3_T8_E1.7650.98
15_F74_E1.7530.98
22_D34_F1.7130.97
7_K66_P1.7130.97
76_Y89_L1.6730.97
22_D51_E1.6240.96
20_E23_K1.6110.96
53_L90_F1.6100.96
44_G49_D1.5830.96
22_D38_L1.5140.94
45_L56_V1.4830.94
3_T6_G1.4690.93
58_Y70_E1.4160.92
93_V101_N1.4050.92
56_V93_V1.3620.90
95_E99_K1.3510.90
39_T106_K1.3260.89
13_F96_E1.3260.89
11_L60_A1.3140.89
44_G52_A1.2430.86
16_G20_E1.2370.86
11_L61_T1.2210.85
21_L24_K1.1980.84
81_D85_D1.1710.82
86_I110_L1.1640.82
22_D35_G1.1550.81
2_L11_L1.1550.81
21_L59_A1.1450.81
54_V74_E1.1380.80
70_E74_E1.1230.79
85_D104_K1.0910.77
25_Y41_L1.0820.77
61_T73_I1.0700.76
6_G75_E1.0680.76
65_K68_P1.0540.75
12_K82_E1.0290.73
15_F102_F1.0290.73
13_F60_A1.0280.73
23_K61_T1.0210.73
29_V32_V1.0110.72
96_E99_K1.0030.71
80_L85_D0.9890.70
97_L103_T0.9880.70
106_K109_K0.9870.70
30_E109_K0.9810.69
2_L46_L0.9100.64
72_D75_E0.8990.63
71_E75_E0.8690.60
52_A55_D0.8660.60
30_E71_E0.8650.60
58_Y67_R0.8600.59
100_S104_K0.8560.59
43_A47_D0.8520.58
17_F60_A0.8430.58
38_L45_L0.8370.57
93_V96_E0.8180.55
94_L98_K0.8060.54
100_S103_T0.8040.54
10_E64_E0.7990.54
21_L25_Y0.7940.53
89_L100_S0.7940.53
72_D76_Y0.7930.53
54_V70_E0.7600.50
77_I88_K0.7530.49
10_E65_K0.7440.48
48_G105_K0.7420.48
1_E10_E0.7410.48
12_K63_T0.7390.48
11_L59_A0.7380.48
58_Y73_I0.7290.47
57_I73_I0.7280.47
19_R77_I0.7260.47
75_E78_E0.7220.46
1_E69_S0.7130.46
103_T107_V0.7110.45
92_E95_E0.6980.44
14_G78_E0.6940.44
35_G96_E0.6910.44
46_L97_L0.6880.43
49_D106_K0.6800.43
4_I50_P0.6720.42
41_L44_G0.6720.42
15_F51_E0.6690.42
14_G17_F0.6680.41
40_Y47_D0.6670.41
12_K102_F0.6560.40
11_L73_I0.6490.40
22_D87_E0.6490.40
4_I17_F0.6480.40
41_L104_K0.6470.40
16_G19_R0.6370.39
80_L89_L0.6290.38
9_Y64_E0.6210.37
37_G43_A0.6140.37
86_I106_K0.6120.37
37_G41_L0.6100.36
22_D60_A0.6080.36
107_V110_L0.6060.36
40_Y54_V0.6060.36
48_G92_E0.6020.36
39_T110_L0.6010.36
49_D98_K0.6000.35
45_L71_E0.5980.35
3_T70_E0.5960.35
97_L107_V0.5960.35
77_I84_E0.5940.35
2_L89_L0.5910.35
69_S91_D0.5900.35
16_G75_E0.5880.34
39_T47_D0.5870.34
72_D108_K0.5830.34
7_K108_K0.5800.34
27_V99_K0.5770.34
26_S30_E0.5740.33
6_G33_K0.5740.33
16_G74_E0.5730.33
59_A73_I0.5700.33
19_R50_P0.5670.33
10_E63_T0.5660.33
21_L34_F0.5660.33
9_Y63_T0.5640.32
4_I9_Y0.5640.32
13_F93_V0.5630.32
38_L77_I0.5630.32
56_V95_E0.5610.32
84_E101_N0.5590.32
11_L68_P0.5570.32
10_E91_D0.5510.31
97_L108_K0.5470.31
35_G86_I0.5440.31
48_G87_E0.5430.31
16_G63_T0.5400.31
37_G42_V0.5390.30
67_R70_E0.5390.30
20_E60_A0.5350.30
25_Y55_D0.5340.30
5_N60_A0.5300.30
23_K33_K0.5210.29
85_D100_S0.5180.29
82_E109_K0.5180.29
60_A93_V0.5160.29
28_E71_E0.5160.29
29_V33_K0.5150.29
24_K83_E0.5100.28
34_F49_D0.5100.28
50_P81_D0.5050.28
83_E92_E0.5020.28
25_Y73_I0.5020.28
16_G62_A0.5010.28
50_P54_V0.5000.27
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
3hnwA 2 0.955 11.6 0.907 Contact Map
2qguA 1 0.5946 11.2 0.907 Contact Map
1t3uA 4 0.7838 9.2 0.911 Contact Map
1no1A 1 0.6036 9 0.911 Contact Map
2mmvA 2 0.6486 8.9 0.911 Contact Map
1fc3A 3 0.7658 8.8 0.912 Contact Map
3b09A 2 0.5495 8.8 0.912 Contact Map
3o7iA 1 0.5766 8.5 0.912 Contact Map
4jerA 1 0.6486 8.4 0.912 Contact Map
4o6uA 1 0.6036 7.9 0.913 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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