GREMLIN Database
DUF3418 - Domain of unknown function (DUF3418)
PFAM: PF11898 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 583 (579)
Sequences: 5814 (4164)
Seq/√Len: 173.0
META: 0.72

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
3_G99_G4.2251.00
248_P251_D4.1491.00
501_A559_V3.9121.00
420_E424_E3.8291.00
30_D33_E3.8101.00
419_D422_A3.6831.00
189_E215_R3.6091.00
338_E343_A3.3311.00
8_Y21_R3.3211.00
180_F265_F3.0791.00
494_H497_R3.0411.00
553_M570_Y3.0251.00
106_W110_E2.8591.00
41_H45_E2.8181.00
362_R409_D2.7951.00
196_I210_A2.7591.00
315_D419_D2.7241.00
522_E574_E2.7111.00
314_G420_E2.6661.00
305_R312_D2.6351.00
264_N279_R2.6201.00
64_E121_R2.6021.00
166_T268_V2.5491.00
454_E503_E2.5421.00
155_E158_A2.5261.00
331_G346_L2.5261.00
471_I502_I2.5121.00
115_D118_F2.5031.00
166_T266_R2.4821.00
337_D363_R2.4641.00
494_H569_A2.3581.00
217_F221_L2.3471.00
40_R82_E2.3401.00
98_S101_H2.2601.00
308_L312_D2.2431.00
307_G341_S2.2131.00
57_H118_F2.1981.00
350_P354_A2.1661.00
236_A252_W2.1391.00
151_S166_T2.1301.00
37_I41_H2.1201.00
142_R147_R2.1131.00
316_L344_L2.0961.00
550_F581_W2.0921.00
82_E86_A2.0831.00
347_F356_A2.0821.00
334_A347_F2.0791.00
140_T147_R2.0081.00
526_L578_E2.0071.00
216_A242_L1.9521.00
11_V19_V1.9331.00
120_T123_D1.9311.00
109_A113_D1.9251.00
451_A503_E1.9151.00
240_R246_R1.9071.00
27_G97_V1.9011.00
559_V566_L1.8971.00
97_V101_H1.8961.00
557_L574_E1.8751.00
551_R555_E1.8611.00
5_V26_Y1.8581.00
363_R367_L1.8571.00
480_P486_A1.8521.00
458_R507_E1.8381.00
229_G237_R1.8281.00
366_L408_L1.8191.00
550_F577_L1.8161.00
305_R308_L1.8121.00
217_F238_E1.8091.00
35_R89_D1.8071.00
310_D368_A1.8031.00
266_R277_E1.8031.00
264_N277_E1.7881.00
25_N28_R1.7831.00
4_Q25_N1.7831.00
148_L165_V1.7721.00
150_L163_V1.7711.00
104_R108_K1.7451.00
167_V175_V1.7341.00
336_V347_F1.7321.00
208_V211_P1.7311.00
52_H103_E1.7141.00
529_R578_E1.7081.00
33_E36_E1.7081.00
36_E40_R1.7061.00
50_T55_L1.6931.00
321_E328_T1.6901.00
26_Y33_E1.6751.00
236_A249_A1.6691.00
165_V180_F1.6591.00
109_A116_L1.6561.00
80_D83_A1.6481.00
276_A287_R1.6441.00
86_A90_A1.6381.00
39_I92_I1.6361.00
10_R17_P1.6341.00
276_A288_L1.6181.00
269_D273_R1.6171.00
318_E418_R1.6161.00
455_V502_I1.6161.00
283_A287_R1.6071.00
504_L565_E1.5941.00
233_D249_A1.5831.00
207_L239_L1.5831.00
253_D256_A1.5741.00
113_D116_L1.5741.00
220_R238_E1.5691.00
487_T495_L1.5561.00
38_F42_A1.5521.00
85_F89_D1.5471.00
62_L78_L1.5391.00
210_A214_A1.5361.00
337_D341_S1.5271.00
477_R527_E1.5191.00
267_V288_L1.5151.00
214_A218_L1.5041.00
338_E345_R1.4991.00
192_V217_F1.4991.00
153_R160_D1.4961.00
424_E428_E1.4951.00
192_V218_L1.4931.00
318_E350_P1.4911.00
109_A112_E1.4891.00
133_T136_D1.4881.00
451_A454_E1.4811.00
458_R503_E1.4731.00
87_F119_L1.4711.00
267_V278_G1.4651.00
274_V277_E1.4651.00
142_R145_G1.4641.00
553_M580_A1.4591.00
491_R494_H1.4531.00
189_E193_T1.4511.00
212_D215_R1.4451.00
17_P20_A1.4421.00
48_W99_G1.4411.00
280_D283_A1.4351.00
195_L232_L1.4341.00
119_L123_D1.4341.00
77_I125_L1.4261.00
357_H361_V1.4251.00
445_V484_V1.4231.00
164_T266_R1.4191.00
365_L427_L1.4151.00
304_E345_R1.4081.00
217_F235_L1.4071.00
84_L119_L1.4051.00
65_V78_L1.4021.00
452_Y456_R1.4001.00
259_P262_R1.3991.00
8_Y23_R1.3951.00
366_L405_A1.3951.00
334_A353_A1.3911.00
313_F344_L1.3881.00
319_T330_T1.3851.00
92_I102_F1.3751.00
412_F430_V1.3731.00
203_L251_D1.3561.00
337_D367_L1.3551.00
451_A500_K1.3481.00
467_A509_L1.3421.00
160_D277_E1.3391.00
526_L574_E1.3371.00
55_L88_Y1.3321.00
41_H47_E1.3271.00
519_R522_E1.3211.00
311_W314_G1.3191.00
278_G283_A1.3131.00
67_E71_K1.3131.00
402_D482_G1.3111.00
306_T343_A1.3081.00
437_T440_E1.3051.00
230_P233_D1.2951.00
493_A496_P1.2951.00
352_E356_A1.2931.00
266_R274_V1.2891.00
198_S252_W1.2881.00
512_D518_Q1.2841.00
265_F281_L1.2821.00
549_E570_Y1.2791.00
368_A427_L1.2781.00
46_G59_R1.2761.00
527_E531_Q1.2741.00
192_V235_L1.2701.00
71_K139_D1.2691.00
375_Y379_N1.2651.00
578_E582_A1.2611.00
28_R97_V1.2581.00
411_L430_V1.2571.00
471_I506_L1.2541.00
137_F186_G1.2541.00
146_L171_L1.2501.00
102_F106_W1.2441.00
571_P576_R1.2431.00
334_A357_H1.2401.00
153_R158_A1.2361.00
7_A26_Y1.2351.00
524_A528_Q1.2331.00
470_D474_Q1.2311.00
520_M524_A1.2301.00
192_V231_L1.2231.00
455_V503_E1.2201.00
307_G343_A1.2121.00
549_E580_A1.2091.00
546_A549_E1.2061.00
518_Q522_E1.2061.00
308_L313_F1.2061.00
198_S255_D1.2051.00
5_V37_I1.2021.00
45_E81_D1.2011.00
96_V101_H1.1991.00
568_T571_P1.1981.00
238_E242_L1.1951.00
207_L243_T1.1951.00
69_E75_R1.1891.00
221_L238_E1.1891.00
193_T210_A1.1821.00
353_A418_R1.1821.00
19_V22_R1.1801.00
468_L472_R1.1791.00
526_L550_F1.1791.00
11_V22_R1.1761.00
106_W114_P1.1731.00
523_V554_L1.1721.00
177_P282_A1.1691.00
150_L263_M1.1671.00
365_L426_L1.1651.00
529_R581_W1.1641.00
482_G486_A1.1631.00
308_L341_S1.1571.00
390_Y394_G1.1561.00
557_L577_L1.1531.00
533_L547_L1.1521.00
52_H102_F1.1521.00
574_E578_E1.1491.00
282_A285_R1.1491.00
448_I495_L1.1441.00
110_E114_P1.1411.00
526_L554_L1.1371.00
196_I217_F1.1371.00
183_L263_M1.1361.00
323_R328_T1.1331.00
181_E230_P1.1301.00
387_A396_V1.1271.00
66_E70_H1.1231.00
238_E241_R1.1201.00
347_F357_H1.1181.00
308_L343_A1.1181.00
163_V263_M1.1131.00
575_K579_K1.1121.00
336_V356_A1.1111.00
56_A60_K1.1111.00
470_D520_M1.1111.00
192_V214_A1.1101.00
474_Q502_I1.1101.00
310_D420_E1.1101.00
517_R521_A1.1051.00
220_R241_R1.1041.00
193_T197_K1.0971.00
63_E66_E1.0911.00
26_Y34_A1.0901.00
29_I34_A1.0871.00
425_A429_A1.0841.00
106_W118_F1.0761.00
10_R20_A1.0711.00
428_E431_R1.0711.00
52_H106_W1.0691.00
220_R242_L1.0601.00
475_L502_I1.0581.00
6_V23_R1.0571.00
48_W102_F1.0561.00
306_T338_E1.0561.00
207_L213_F1.0551.00
410_R489_W1.0531.00
528_Q532_R1.0531.00
306_T345_R1.0521.00
401_D405_A1.0490.99
398_A481_P1.0460.99
82_E85_F1.0410.99
500_K504_L1.0390.99
358_R409_D1.0390.99
203_L248_P1.0340.99
198_S254_L1.0310.99
342_V363_R1.0300.99
183_L187_L1.0280.99
177_P285_R1.0250.99
143_L179_R1.0230.99
342_V367_L1.0220.99
479_V495_L1.0190.99
361_V365_L1.0170.99
36_E85_F1.0120.99
67_E70_H1.0110.99
402_D485_A1.0100.99
83_A86_A1.0070.99
229_G234_A1.0060.99
26_Y29_I1.0060.99
62_L66_E1.0040.99
12_T17_P1.0030.99
176_D179_R0.9990.99
530_Y554_L0.9980.99
356_A359_A0.9970.99
491_R549_E0.9940.99
349_T352_E0.9920.99
217_F239_L0.9910.99
72_A132_V0.9890.99
341_S363_R0.9880.99
341_S367_L0.9870.99
57_H60_K0.9860.99
247_V252_W0.9850.99
6_V25_N0.9850.99
194_A197_K0.9770.99
395_S398_A0.9750.99
338_E341_S0.9730.99
226_P229_G0.9720.99
258_P261_L0.9720.99
456_R472_R0.9710.99
527_E530_Y0.9710.99
375_Y435_V0.9680.99
444_L448_I0.9680.99
477_R555_E0.9680.99
403_L484_V0.9670.99
533_L550_F0.9640.99
321_E330_T0.9630.99
35_R39_I0.9620.99
577_L581_W0.9610.99
525_P529_R0.9600.99
65_V121_R0.9590.99
390_Y449_L0.9580.99
232_L254_L0.9550.99
494_H559_V0.9540.99
163_V187_L0.9540.99
39_I89_D0.9540.99
11_V18_I0.9520.99
195_L231_L0.9520.99
472_R476_A0.9520.99
425_A428_E0.9510.99
323_R326_G0.9500.99
530_Y534_L0.9490.99
248_P252_W0.9480.99
515_R519_R0.9470.99
549_E553_M0.9470.99
526_L557_L0.9450.99
410_R437_T0.9430.99
196_I207_L0.9430.99
88_Y119_L0.9430.99
188_L191_K0.9420.99
25_N98_S0.9400.99
194_A258_P0.9370.99
427_L431_R0.9350.99
336_V345_R0.9310.99
336_V343_A0.9310.99
61_L121_R0.9300.99
151_S266_R0.9300.99
42_A47_E0.9270.99
278_G287_R0.9210.99
164_T264_N0.9200.99
305_R343_A0.9190.99
567_G571_P0.9180.99
382_N385_K0.9180.99
3_G48_W0.9170.99
27_G34_A0.9170.99
480_P487_T0.9160.99
368_A423_F0.9150.99
9_E22_R0.9140.99
435_V439_Q0.9130.99
546_A580_A0.9110.99
50_T103_E0.9110.99
183_L257_L0.9090.99
189_E214_A0.9010.98
474_Q558_R0.8970.98
86_A89_D0.8970.98
193_T218_L0.8960.98
497_R559_V0.8950.98
467_A520_M0.8890.98
206_N213_F0.8880.98
79_V83_A0.8860.98
2_R6_V0.8830.98
514_A518_Q0.8820.98
307_G367_L0.8820.98
60_K64_E0.8800.98
50_T56_A0.8800.98
357_H418_R0.8760.98
38_F102_F0.8750.98
522_E557_L0.8750.98
450_A454_E0.8740.98
365_L412_F0.8740.98
5_V38_F0.8730.98
168_P171_L0.8710.98
109_A114_P0.8710.98
93_P96_V0.8710.98
7_A29_I0.8700.98
114_P118_F0.8670.98
533_L581_W0.8650.98
275_L288_L0.8640.98
2_R23_R0.8630.98
491_R569_A0.8620.98
522_E561_L0.8610.98
183_L191_K0.8610.98
69_E76_D0.8570.98
447_A500_K0.8560.98
474_Q477_R0.8560.98
525_P574_E0.8550.98
309_T340_D0.8500.98
537_L542_A0.8490.98
165_V263_M0.8480.98
196_I214_A0.8470.98
26_Y30_D0.8460.98
527_E554_L0.8440.98
32_A94_A0.8430.98
537_L544_D0.8420.98
488_P491_R0.8410.98
309_T367_L0.8410.98
169_L275_L0.8400.98
237_R241_R0.8400.98
127_H133_T0.8390.98
40_R45_E0.8390.98
30_D36_E0.8390.98
33_E37_I0.8330.97
550_F580_A0.8330.97
240_R243_T0.8330.97
202_A205_R0.8330.97
498_Y569_A0.8320.97
361_V416_L0.8310.97
102_F110_E0.8310.97
216_A220_R0.8280.97
411_L437_T0.8280.97
529_R532_R0.8250.97
232_L236_A0.8210.97
30_D34_A0.8210.97
145_G174_Q0.8210.97
213_F243_T0.8190.97
48_W55_L0.8170.97
167_V267_V0.8160.97
508_K565_E0.8140.97
90_A123_D0.8140.97
52_H110_E0.8130.97
53_P57_H0.8100.97
106_W109_A0.8090.97
440_E443_R0.8090.97
320_V331_G0.8080.97
315_D421_A0.8060.97
337_D342_V0.8060.97
129_A132_V0.8040.97
444_L447_A0.8030.97
376_L438_A0.8020.97
198_S256_A0.7970.97
526_L529_R0.7960.97
429_A433_R0.7940.97
121_R125_L0.7890.96
65_V124_L0.7890.96
292_A296_F0.7870.96
225_P228_D0.7860.96
518_Q521_A0.7820.96
359_A362_R0.7820.96
148_L167_V0.7820.96
501_A563_A0.7810.96
213_F217_F0.7800.96
100_R104_R0.7790.96
148_L175_V0.7770.96
405_A485_A0.7770.96
215_R219_A0.7760.96
426_L429_A0.7750.96
24_V29_I0.7750.96
456_R476_A0.7700.96
491_R496_P0.7680.96
421_A425_A0.7680.96
403_L407_A0.7660.96
308_L344_L0.7650.96
56_A59_R0.7650.96
57_H61_L0.7650.96
5_V27_G0.7640.96
134_E139_D0.7640.96
42_A48_W0.7630.96
53_P56_A0.7630.96
70_H75_R0.7630.96
421_A424_E0.7630.96
530_Y547_L0.7630.96
189_E218_L0.7630.96
471_I474_Q0.7610.96
540_G544_D0.7600.96
311_W315_D0.7590.96
141_L165_V0.7570.96
567_G570_Y0.7550.95
61_L119_L0.7540.95
111_R114_P0.7540.95
545_P549_E0.7530.95
221_L234_A0.7520.95
213_F242_L0.7510.95
61_L64_E0.7510.95
504_L507_E0.7510.95
165_V265_F0.7510.95
444_L493_A0.7500.95
427_L430_V0.7490.95
307_G340_D0.7470.95
254_L262_R0.7470.95
7_A34_A0.7460.95
424_E427_L0.7450.95
149_P166_T0.7440.95
553_M572_V0.7430.95
519_R564_Q0.7430.95
101_H104_R0.7430.95
48_W52_H0.7400.95
110_E113_D0.7380.95
541_R544_D0.7380.95
422_A425_A0.7380.95
412_F426_L0.7370.95
296_F331_G0.7370.95
568_T576_R0.7370.95
507_E511_A0.7360.95
537_L540_G0.7350.95
210_A213_F0.7340.95
216_A243_T0.7340.95
110_E116_L0.7340.95
51_R56_A0.7330.95
459_L471_I0.7330.95
55_L59_R0.7320.95
359_A405_A0.7320.95
34_A37_I0.7310.95
491_R552_W0.7310.95
467_A471_I0.7300.95
317_P333_P0.7290.95
406_A441_V0.7290.95
512_D519_R0.7280.94
564_Q568_T0.7260.94
477_R531_Q0.7260.94
403_L441_V0.7250.94
229_G233_D0.7240.94
52_H55_L0.7240.94
514_A517_R0.7240.94
479_V483_F0.7230.94
447_A451_A0.7230.94
304_E343_A0.7220.94
389_A450_A0.7210.94
195_L254_L0.7210.94
10_R21_R0.7210.94
451_A455_V0.7200.94
448_I496_P0.7190.94
188_L231_L0.7190.94
173_N296_F0.7180.94
448_I479_V0.7180.94
487_T491_R0.7170.94
35_R93_P0.7160.94
360_G363_R0.7100.94
172_L281_L0.7100.94
49_D99_G0.7090.94
193_T215_R0.7090.94
334_A356_A0.7080.94
311_W367_L0.7080.94
178_E230_P0.7070.94
36_E89_D0.7060.94
371_S375_Y0.7040.93
5_V25_N0.7040.93
473_A531_Q0.7030.93
351_A354_A0.7010.93
54_F58_N0.7010.93
281_L285_R0.7000.93
507_E510_P0.7000.93
491_R570_Y0.6990.93
315_D420_E0.6980.93
254_L257_L0.6970.93
379_N439_Q0.6940.93
342_V360_G0.6940.93
503_E507_E0.6940.93
440_E493_A0.6930.93
172_L284_L0.6920.93
375_Y439_Q0.6910.93
463_K472_R0.6880.93
394_G449_L0.6880.93
13_L18_I0.6870.93
169_L288_L0.6850.93
366_L373_L0.6850.93
59_R63_E0.6840.92
369_L427_L0.6840.92
7_A24_V0.6840.92
108_K112_E0.6830.92
573_S576_R0.6820.92
526_L581_W0.6810.92
523_V527_E0.6790.92
169_L292_A0.6790.92
5_V34_A0.6780.92
236_A240_R0.6780.92
181_E232_L0.6770.92
125_L129_A0.6770.92
417_P426_L0.6760.92
456_R475_L0.6740.92
520_M523_V0.6720.92
365_L413_L0.6710.92
526_L577_L0.6710.92
473_A476_A0.6710.92
451_A499_L0.6700.92
106_W116_L0.6690.92
115_D120_T0.6690.92
159_P264_N0.6680.92
198_S257_L0.6680.92
150_L165_V0.6670.91
232_L249_A0.6660.91
436_D440_E0.6660.91
473_A527_E0.6660.91
110_E118_F0.6660.91
62_L84_L0.6650.91
190_E260_H0.6640.91
310_D424_E0.6630.91
184_V187_L0.6610.91
552_W555_E0.6600.91
208_V212_D0.6590.91
455_V499_L0.6580.91
433_R437_T0.6560.91
406_A410_R0.6550.91
465_L469_A0.6550.91
508_K519_R0.6540.91
360_G367_L0.6540.91
362_R366_L0.6540.91
64_E67_E0.6530.91
337_D360_G0.6530.91
196_I213_F0.6520.91
348_D352_E0.6500.90
84_L124_L0.6500.90
127_H131_G0.6500.90
8_Y20_A0.6500.90
560_S568_T0.6490.90
69_E74_R0.6480.90
443_R447_A0.6470.90
218_L221_L0.6470.90
29_I33_E0.6470.90
439_Q443_R0.6450.90
337_D340_D0.6440.90
309_T341_S0.6440.90
103_E106_W0.6430.90
87_F91_R0.6430.90
198_S253_D0.6430.90
550_F553_M0.6400.90
91_R123_D0.6390.90
373_L404_L0.6390.90
282_A286_A0.6390.90
237_R240_R0.6380.90
40_R85_F0.6370.90
512_D515_R0.6360.89
62_L119_L0.6360.89
522_E525_P0.6350.89
92_I96_V0.6350.89
405_A408_L0.6350.89
163_V183_L0.6340.89
368_A424_E0.6330.89
357_H360_G0.6330.89
391_A394_G0.6330.89
102_F114_P0.6320.89
528_Q531_Q0.6310.89
193_T214_A0.6310.89
215_R218_L0.6290.89
519_R561_L0.6290.89
50_T99_G0.6290.89
76_D79_V0.6290.89
191_K263_M0.6250.89
352_E355_A0.6220.88
320_V346_L0.6210.88
213_F216_A0.6210.88
300_A303_A0.6210.88
37_I47_E0.6210.88
402_D406_A0.6200.88
28_R34_A0.6190.88
560_S564_Q0.6190.88
458_R461_G0.6150.88
206_N245_V0.6140.88
440_E489_W0.6140.88
388_L391_A0.6140.88
524_A527_E0.6130.88
68_L72_A0.6130.88
470_D558_R0.6120.88
533_L537_L0.6120.88
167_V265_F0.6120.88
102_F116_L0.6110.88
159_P259_P0.6110.88
557_L561_L0.6100.87
428_E432_A0.6090.87
319_T350_P0.6090.87
157_G259_P0.6070.87
176_D181_E0.6050.87
167_V180_F0.6050.87
249_A252_W0.6040.87
143_L176_D0.6040.87
362_R405_A0.6040.87
173_N348_D0.6030.87
447_A450_A0.6020.87
141_L150_L0.6020.87
153_R159_P0.6020.87
410_R441_V0.6020.87
141_L191_K0.5990.86
259_P279_R0.5990.86
408_L430_V0.5970.86
40_R81_D0.5970.86
516_D520_M0.5960.86
322_I331_G0.5960.86
500_K503_E0.5950.86
153_R157_G0.5950.86
496_P500_K0.5950.86
243_T252_W0.5950.86
373_L408_L0.5950.86
577_L580_A0.5940.86
538_P541_R0.5930.86
276_A284_L0.5930.86
100_R103_E0.5910.86
95_D101_H0.5910.86
456_R460_K0.5900.86
32_A36_E0.5900.86
519_R525_P0.5900.86
178_E229_G0.5890.86
532_R536_A0.5880.85
284_L288_L0.5870.85
58_N88_Y0.5860.85
313_F316_L0.5860.85
406_A484_V0.5850.85
407_A441_V0.5840.85
411_L433_R0.5840.85
494_H566_L0.5820.85
216_A219_A0.5820.85
213_F238_E0.5810.85
579_K582_A0.5790.85
167_V263_M0.5790.85
68_L76_D0.5790.85
455_V506_L0.5760.84
455_V458_R0.5760.84
208_V213_F0.5750.84
347_F353_A0.5740.84
564_Q567_G0.5730.84
305_R346_L0.5730.84
173_N289_G0.5710.84
307_G337_D0.5710.84
268_V272_G0.5710.84
473_A524_A0.5700.84
482_G485_A0.5690.84
441_V489_W0.5690.84
406_A489_W0.5690.84
484_V492_L0.5670.83
344_L361_V0.5660.83
141_L263_M0.5650.83
407_A438_A0.5630.83
491_R548_E0.5620.83
121_R124_L0.5620.83
151_S160_D0.5620.83
212_D216_A0.5620.83
383_L387_A0.5610.83
171_L174_Q0.5610.83
7_A27_G0.5610.83
106_W113_D0.5600.83
239_L243_T0.5600.83
556_E568_T0.5600.83
444_L496_P0.5600.83
547_L581_W0.5590.83
457_K461_G0.5580.82
297_A300_A0.5580.82
418_R422_A0.5570.82
166_T274_V0.5570.82
190_E193_T0.5570.82
305_R344_L0.5570.82
385_K389_A0.5570.82
452_Y502_I0.5560.82
108_K111_R0.5560.82
129_A133_T0.5560.82
563_A566_L0.5560.82
318_E353_A0.5550.82
560_S572_V0.5550.82
175_V179_R0.5540.82
69_E77_I0.5530.82
511_A515_R0.5520.82
354_A418_R0.5520.82
344_L347_F0.5520.82
236_A248_P0.5500.82
525_P578_E0.5490.81
59_R62_L0.5490.81
559_V569_A0.5490.81
299_A303_A0.5490.81
76_D126_R0.5490.81
506_L510_P0.5470.81
234_A237_R0.5460.81
70_H77_I0.5460.81
62_L65_V0.5460.81
455_V459_L0.5440.81
452_Y475_L0.5440.81
340_D363_R0.5430.81
394_G398_A0.5430.81
292_A295_A0.5430.81
531_Q534_L0.5420.81
322_I329_V0.5420.81
367_L423_F0.5400.80
369_L408_L0.5400.80
62_L124_L0.5400.80
537_L541_R0.5390.80
437_T489_W0.5390.80
568_T572_V0.5380.80
83_A126_R0.5380.80
576_R579_K0.5370.80
48_W103_E0.5370.80
382_N386_L0.5370.80
68_L77_I0.5370.80
315_D422_A0.5360.80
305_R314_G0.5360.80
4_Q27_G0.5360.80
530_Y533_L0.5360.80
195_L252_W0.5350.80
313_F335_L0.5340.80
159_P277_E0.5330.79
403_L445_V0.5330.79
397_E400_R0.5320.79
354_A416_L0.5320.79
35_R94_A0.5310.79
523_V561_L0.5310.79
191_K257_L0.5310.79
453_H457_K0.5310.79
217_F242_L0.5310.79
206_N239_L0.5300.79
372_P408_L0.5300.79
389_A446_A0.5290.79
154_F208_V0.5290.79
60_K63_E0.5290.79
184_V263_M0.5290.79
433_R440_E0.5250.78
396_V400_R0.5250.78
165_V179_R0.5250.78
55_L92_I0.5250.78
7_A69_E0.5240.78
477_R480_P0.5240.78
306_T341_S0.5230.78
390_Y393_L0.5230.78
103_E110_E0.5220.78
489_W493_A0.5220.78
125_L132_V0.5220.78
361_V417_P0.5220.78
578_E581_W0.5200.78
107_K111_R0.5200.78
195_L198_S0.5200.78
111_R116_L0.5190.78
70_H153_R0.5180.78
39_I44_V0.5160.77
296_F348_D0.5160.77
467_A517_R0.5150.77
192_V221_L0.5140.77
79_V119_L0.5140.77
408_L412_F0.5140.77
105_W116_L0.5130.77
160_D279_R0.5130.77
311_W316_L0.5130.77
521_A524_A0.5130.77
240_R252_W0.5120.77
7_A25_N0.5110.77
381_P400_R0.5110.77
95_D108_K0.5100.76
365_L369_L0.5100.76
182_W226_P0.5100.76
175_V180_F0.5100.76
523_V557_L0.5090.76
228_D234_A0.5090.76
3_G98_S0.5080.76
332_Y350_P0.5080.76
61_L65_V0.5080.76
143_L175_V0.5050.76
194_A257_L0.5040.76
203_L206_N0.5030.75
42_A55_L0.5030.75
51_R107_K0.5030.75
92_I116_L0.5020.75
187_L261_L0.5020.75
446_A450_A0.5020.75
311_W423_F0.5020.75
172_L267_V0.5010.75
182_W234_A0.5010.75
173_N331_G0.5010.75
177_P181_E0.5000.75
362_R408_L0.5000.75
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
1pd3A 2 0.0738 11.8 0.984 Contact Map
2a3dA 1 0.1235 11.2 0.984 Contact Map
3vfzA 2 0.1029 9.7 0.984 Contact Map
1wpbA 6 0.2693 8.8 0.984 Contact Map
2fkiA 1 0.1509 8.4 0.985 Contact Map
4ykcA 1 0.1063 8.1 0.985 Contact Map
4g6dA 1 0.0943 7.9 0.985 Contact Map
2ebmA 1 0.2127 7.3 0.985 Contact Map
1lbqA 2 0.3293 6.8 0.985 Contact Map
3whrA 1 0.3705 6.4 0.985 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

Page generated in 0.0147 seconds.