GREMLIN Database
Phage_TAC_11 - Phage tail tube protein, GTA-gp10
PFAM: PF11836 Sequences:
Download Alignment
We filter this alignment to remove sites that have many gaps before running GREMLIN.

Date: 2015_10
Length: 98 (95)
Sequences: 3413 (2404)
Seq/√Len: 246.7
META: 0.834

GREMLIN Results:

Legend: The darker and larger the blue dots, the higher coevolution strength.

Residue pairs sorted by coevolution strength:
i j Sco Prob
18_T21_A3.8601.00
5_E12_E3.8411.00
7_V12_E3.3351.00
39_R49_D2.7401.00
35_A44_R2.6211.00
23_A48_R2.4801.00
26_E33_L2.4431.00
13_R63_E2.1961.00
86_R90_A2.1251.00
29_L36_L2.1161.00
55_R67_D2.1061.00
24_E59_R1.8391.00
66_T69_D1.8311.00
1_R16_R1.7331.00
55_R59_R1.6731.00
31_A39_R1.6711.00
50_L88_A1.6521.00
6_L87_I1.5961.00
28_A52_A1.4921.00
91_L95_A1.4881.00
5_E14_T1.4311.00
90_A94_A1.3471.00
3_E16_R1.3341.00
54_I91_L1.3051.00
58_L70_V1.2711.00
34_F38_E1.2631.00
7_V10_G1.2331.00
38_E44_R1.1991.00
27_A46_S1.1861.00
57_G91_L1.1611.00
75_I84_A1.1601.00
89_A93_A1.1551.00
37_V41_E1.1411.00
50_L84_A1.1291.00
83_G86_R1.1281.00
29_L52_A1.1271.00
3_E14_T1.0961.00
54_I84_A1.0791.00
31_A36_L1.0731.00
68_A72_A1.0641.00
31_A35_A1.0581.00
13_R58_L1.0321.00
29_L32_G1.0241.00
51_L77_G1.0161.00
9_G74_V1.0071.00
8_L13_R1.0011.00
30_G46_S0.9731.00
22_L33_L0.9661.00
24_E28_A0.9661.00
6_L15_L0.9641.00
83_G87_I0.9551.00
21_A56_A0.9511.00
34_F45_L0.9381.00
24_E56_A0.9361.00
8_L15_L0.9231.00
64_D72_A0.9171.00
45_L85_A0.8851.00
32_G35_A0.8801.00
19_L23_A0.8771.00
38_E42_S0.8690.99
73_A78_G0.8620.99
27_A48_R0.8610.99
94_A97_G0.8600.99
4_V7_V0.8600.99
82_A86_R0.8550.99
87_I91_L0.8480.99
51_L70_V0.8360.99
10_G75_I0.8340.99
17_L91_L0.8290.99
17_L57_G0.8280.99
88_A92_L0.8180.99
68_A71_L0.8170.99
10_G13_R0.8050.99
15_L87_I0.7990.99
69_D73_A0.7990.99
65_V73_A0.7900.99
59_R62_G0.7760.99
70_V74_V0.7720.99
52_A56_A0.7620.99
64_D67_D0.7590.99
25_L57_G0.7500.98
84_A87_I0.7460.98
52_A55_R0.7420.98
54_I88_A0.7370.98
70_V73_A0.7350.98
51_L71_L0.7250.98
15_L91_L0.6990.98
7_V76_E0.6940.97
26_E48_R0.6890.97
72_A76_E0.6860.97
85_A89_A0.6790.97
40_F53_L0.6750.97
1_R15_L0.6750.97
67_D70_V0.6730.97
38_E41_E0.6630.97
35_A38_E0.6450.96
25_L36_L0.6440.96
57_G61_G0.6430.96
81_L84_A0.6410.96
40_F92_L0.6330.96
34_F85_A0.6300.95
90_A93_A0.6290.95
34_F41_E0.6280.95
65_V69_D0.6280.95
76_E84_A0.6250.95
46_S49_D0.6250.95
34_F50_L0.6200.95
20_G24_E0.6140.95
13_R61_G0.6070.95
31_A46_S0.6050.94
25_L56_A0.6030.94
64_D68_A0.6000.94
25_L40_F0.5990.94
16_R20_G0.5930.94
25_L53_L0.5930.94
23_A47_A0.5920.94
31_A34_F0.5870.93
11_E64_D0.5840.93
40_F85_A0.5820.93
81_L85_A0.5790.93
20_G23_A0.5750.93
57_G60_G0.5740.93
19_L25_L0.5730.93
19_L47_A0.5720.93
85_A93_A0.5650.92
74_V78_G0.5610.92
58_L61_G0.5600.92
55_R65_V0.5570.92
30_G35_A0.5550.91
53_L88_A0.5520.91
9_G13_R0.5480.91
31_A37_V0.5410.90
59_R68_A0.5370.90
29_L53_L0.5200.89
77_G84_A0.5190.89
19_L77_G0.5180.88
35_A46_S0.5150.88
51_L74_V0.5130.88
38_E43_G0.5120.88
54_I57_G0.5090.88
17_L60_G0.5010.87
32_G46_S0.5000.87
Legend: The i and j are positions as given in the UniProt sequence. Only predictions with Prob ≥ 0.7 are listed. For all 3L/2 predictions, click on one of the links below.

Sco = ((raw_sco - min_sco)/(avg_sco - min_sco))/2 + 0.5
Prob = P(contact | Sco, seq80/√len)
seq80 = effective number of sequences, after reducing redundancy to 80% identity

HHsearch Results:
Legend: GREMLIN results (Prob ≥ 0.7) overlaid on top PDB hits. The grey/red filled circles underneath are pdb residue contacts (min distance < 5 Angstroms). The shade of the circles is based on the top 10 (or top 20 if e-value < 1E-20) HHsearch results which uses the overall probability and per-site alignment prob. Inter oligomeric contacts in the pdb are in shades of red.
PDB Chains Cov % HHΔ  
2lojA 1 0.2755 19.6 0.865 Contact Map
4ynxA 2 0.2755 18.9 0.866 Contact Map
2jraA 2 0.2755 17.8 0.868 Contact Map
4p1mA 4 0.9286 6.7 0.891 Contact Map
2lc0A 1 0.8469 5.3 0.896 Contact Map
4e1rA 2 0.4082 5.1 0.896 Contact Map
1t3uA 4 0.9286 4.3 0.9 Contact Map
2mmvA 2 0.7959 4.3 0.9 Contact Map
4e1pA 2 0.4082 4.2 0.901 Contact Map
1b7yB 2 0.3878 3.9 0.902 Contact Map

Sequence Conservation (Image Generated using WebLogo v3)
Legend: Color is used to show Hydrophobicity (Blue: Hydrophilic, Green: Neutral and Black: Hydrophobic). Amount of gaps is represented by width.

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